theophylline has been researched along with uracil in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (29.41) | 18.7374 |
| 1990's | 9 (26.47) | 18.2507 |
| 2000's | 8 (23.53) | 29.6817 |
| 2010's | 7 (20.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Boersma, YL; Dekker, FJ; Dömling, ASS; Eleftheriadis, N; Wójcik, M; Zwinderman, MRH | 1 |
| Beitins, IZ; Kilbane, AJ; Manis, M; Silbart, LK; Weber, WW | 1 |
| Butler, MA; Kadlubar, FF; Lang, NP; Massengill, JP; Talaska, G; Teitel, CH | 1 |
| Spector, R | 1 |
| Chilcote, DD; Mrochek, JE | 1 |
| Phelps, P; Tse, RL; Urban, D | 1 |
| Bacon, V; Duffield, AM; Halpern, B; Hoyano, Y; Pereira, WE; Summons, RE | 1 |
| Chetverikov, BV; Churakov, AP; Gorodilova, AF; Volynskaia, TM | 1 |
| Connors, KA; Mollica, JA | 1 |
| Hedrick, CE; Koeppel, TA | 1 |
| Bonati, M; Garattini, S; Latini, R; Marzi, E | 1 |
| Bresnick, E; McQuilkin, SH; Nierenberg, DW | 1 |
| Galteau, MM; Gueguen, R; Pontes, ZB; Siest, G; Vincent-Viry, M | 1 |
| Jenison, RD; Pardi, A; Shields, TP; Wick, CL; Zimmermann, GR | 1 |
| Ayrton, J; Dear, GJ; Leavens, WJ; Mallett, DN; Plumb, RS | 1 |
| Bernal, ML; Fanlo, A; Juste, JL; Lanuza, J; Mayayo, E; Sáenz, MA; Sinués, B | 1 |
| Devichenskiĭ, VM; Kriukov, LN; Kriukova, LIu; Kuznetsov, SL; Leonov, ON; Mel'nik, EI; Tsirenina, ML; Vorontsov, EA | 1 |
| Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT | 1 |
| Cao, XM; Lin, SS; Lu, JF; Yi, T; Zhuo, HT | 1 |
| Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y | 1 |
| JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
| SIMON, MI; VANVUNAKIS, H | 1 |
| Li, J; Peng, XQ; Xu, JP; Zhang, J | 1 |
| Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A | 1 |
| Brea, J; Hierrezuelo, J; López-Romero, JM; Loza, MI; Pérez-González, M; Rico-Gómez, R | 1 |
| Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S | 1 |
| Chester, TL; Stalcup, AM | 1 |
| Fan, XR; Li, XY; Li, YF; Li, YP; Liu, YN; Yang, M; Yao, XC; Yin, YM; Yuan, M; Zhu, JB | 1 |
| Asakura, M; Asano, Y; Asanuma, H; Ihara, M; Kato, H; Kitakaze, M; Minamino, T; Mochizuki, N; Mori, H; Shinozaki, Y; Sugimachi, M; Yamazaki, S | 1 |
| Ahluwalia, N; Pao, CI; Pfeiffer, CM; Rybak, ME; Sternberg, MR | 1 |
34 other study(ies) available for theophylline and uracil
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.
Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Streptococcus pyogenes; Structure-Activity Relationship | 2019 |
Human N-acetylation genotype determination with urinary caffeine metabolites.
Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Gene Frequency; Genetics, Population; Genotype; Humans; Nitrogen; Pedigree; Phenotype; Theophylline; Time Factors; Uracil; Uric Acid; Xanthines | 1990 |
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites.
Topics: Acetylation; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Disease Susceptibility; Humans; Isoenzymes; Oxidation-Reduction; Phenotype; Theophylline; Uracil; Urinary Bladder Neoplasms; Xanthines | 1990 |
Hypoxanthine transport through the blood-brain barrier.
Topics: Adenine; Animals; Blood-Brain Barrier; Hypoxanthine; Hypoxanthines; Inosine; Leucine; Probenecid; Rats; Rats, Inbred Strains; Theophylline; Thiamine; Uracil | 1987 |
Use of automatic digital data acquisition and on-line computer analysis in high-resolution liquid chromatography.
Topics: Autoanalysis; Chromatography; Computers; Cyclic N-Oxides; Hippurates; Hypoxanthines; Mathematics; Methods; Niacinamide; Nicotinic Acids; Orotic Acid; Pyrimidines; Ribonucleosides; Spectrophotometry; Theophylline; Ultraviolet Rays; Uracil; Uric Acid; Xanthines | 1971 |
Polymorphonuclear leukocyte motility in vitro. VI. Effect of purine and pyrimidine analogues: possible role of cyclic AMP.
Topics: Adenine; Caffeine; Cyclic AMP; Epinephrine; Guanine; Guanosine; Humans; Hypoxanthines; Imidazoles; Leukocytes; Movement; Purines; Pyrimidines; Reserpine; Structure-Activity Relationship; Theophylline; Thymine; Uracil; Uric Acid; Xanthines | 1972 |
Chlorination studies. IV. The reaction of aqueous hypochlorous acid with pyrimidine and purine bases.
Topics: Adenine; Bromouracil; Caffeine; Chemical Phenomena; Chemistry; Guanine; Mass Spectrometry; Purines; Pyrimidines; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Theophylline; Thymine; Uracil; Xanthines | 1973 |
[Improvement of the method of production of the diacetyl derivative of 4,5-diaminouracil in the production of theophylline].
Topics: Technology, Pharmaceutical; Theophylline; Uracil | 1966 |
Modification of reaction rates by complex formation. II. Inhibition of the rate of alkaline hydrolysis of methyl trans-cinnamate by some heterocyclic compounds.
Topics: Acetates; Benzimidazoles; Caffeine; Chemical Phenomena; Chemistry; Cinnamates; Guanine; Imidazoles; Purines; Theophylline; Uracil | 1967 |
Effect of functional group substituents on the paper chromatography of purines and pyrimidines.
Topics: Adenine; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; Guanine; Hydrogen-Ion Concentration; Nitriles; Purines; Pyrimidines; Theobromine; Theophylline; Thymine; Uracil; Water; Xanthines | 1967 |
Urinary excretion of an uracilic metabolite from caffeine by rat, monkey and man.
Topics: Adult; Animals; Biotransformation; Caffeine; Humans; Macaca fascicularis; Male; Rats; Species Specificity; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1981 |
Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Genetic Variation; Humans; Male; Middle Aged; Oxidoreductases; Phenotype; Spectrophotometry, Ultraviolet; Theophylline; Time Factors; Uracil; Xanthines | 1995 |
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes.
Topics: Acetylation; Adolescent; Adult; Alleles; Arylamine N-Acetyltransferase; Caffeine; Child; Chromatography, High Pressure Liquid; Family; Female; Gene Frequency; Genes, Recessive; Humans; Male; Middle Aged; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Genetic; Theophylline; Uracil; Uric Acid; Xanthines | 1994 |
A semiconserved residue inhibits complex formation by stabilizing interactions in the free state of a theophylline-binding RNA.
Topics: Adenine; Bacteriophage T7; Base Sequence; Binding Sites; Conserved Sequence; Cytosine; DNA-Directed RNA Polymerases; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Nuclear Magnetic Resonance, Biomolecular; RNA, Viral; Theophylline; Uracil; Viral Proteins | 1998 |
Use of generic fast gradient liquid chromatography-tandem mass spectroscopy in quantitative bioanalysis.
Topics: Acetanilides; Animals; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cresols; Ketones; Mass Spectrometry; Pharmaceutical Preparations; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Theophylline; Uracil | 1998 |
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow.
Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Environmental Exposure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutagens; Rheology; Smoking; Theophylline; Time Factors; Uracil; Uric Acid; Urination; Xanthines | 1999 |
[Synthesis of uracil and theophylline derivatives and study of their effect on glucose transport in rat hepatic cells].
Topics: Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Liver; Phosphodiesterase Inhibitors; Rats; Theophylline; Uracil | 2000 |
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines | 1997 |
[HPLC determination of five caffeine metabolites].
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Theophylline; Uracil; Uric Acid; Xanthines | 1997 |
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines | 2002 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
THE DYE-SENSITIZED PHOTOOXIDATION OF PURINE AND PYRIMIDINE DERIVATIVES.
Topics: Caffeine; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Infrared Rays; Light; Manometry; Methylene Blue; Nucleosides; Oxidation-Reduction; Purines; Research; Theobromine; Theophylline; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uric Acid; Xanthines | 1964 |
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe].
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Female; Humans; Male; Mixed Function Oxygenases; Theophylline; Uracil; Uric Acid; Xanthines | 2006 |
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines | 2007 |
Synthesis of new mannosyl, galactosyl and glucosyl theophylline nucleosides with potential activity as antagonists of adenosine receptors. DEMA-induced cyclization of glycosylideneiminouracils.
Topics: Acetates; Binding, Competitive; Cyclization; Galactose; Glucose; Humans; Imines; Magnetic Resonance Spectroscopy; Mannose; Molecular Structure; Nucleosides; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recombinant Proteins; Theophylline; Uracil | 2008 |
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines | 2008 |
Interactions between minimum run time, modifier concentration, and efficiency parameters in a high performance liquid chromatography separation.
Topics: Chromatography, High Pressure Liquid; Methanol; Models, Chemical; Niacinamide; Pressure; Resorcinols; Theobromine; Theophylline; Time Factors; Uracil | 2011 |
[Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2].
Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Medicine, Tibetan Traditional; Rats; Rats, Sprague-Dawley; RNA, Messenger; Theophylline; Uracil; Uric Acid; Xanthines | 2014 |
An interaction between glucagon-like peptide-1 and adenosine contributes to cardioprotection of a dipeptidyl peptidase 4 inhibitor from myocardial ischemia-reperfusion injury.
Topics: Adenosine; Adenosine Deaminase; Animals; Apoptosis; Cardiotonic Agents; Cyclic AMP Response Element-Binding Protein; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dogs; Extracellular Signal-Regulated MAP Kinases; Female; Glucagon-Like Peptide 1; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hemodynamics; Myocardial Reperfusion Injury; Piperidines; Protein Binding; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Antagonists; Theophylline; Uracil | 2015 |
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake.
Topics: Adolescent; Adult; Biomarkers; Black or African American; Caffeine; Child; Chromatography, Liquid; Cross-Sectional Studies; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutrition Surveys; Tandem Mass Spectrometry; Theophylline; Uracil; Uric Acid; White People; Xanthines; Young Adult | 2015 |