Compounds > theophylline

theophylline and troleandomycin

theophylline has been researched along with troleandomycin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's6 (30.00)18.2507
2000's1 (5.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chidsey, C; Hudgel, D; Spector, S; Weinberger, M1
Weinberger, M1
Szefler, SJ1
Brenner, AM; Hill, MR; Kamada, AK; Szefler, SJ1
Cash, M; Shivaram, U1
Berezhinskaia, VV; Dolgova, GV1
Advenier, C; Naline, E; Pays, M; Sanceaume, M1
Farr, RS; Friedman, BF; Wald, JA1
André, P; Descotes, J; Evreux, JC1
Hemsworth, TC; Renton, KW1
Eaton, DL; Gallagher, EP; Kunze, KL; Stapleton, PL; Wienkers, LC1
Huang, SL; Ou-Yang, DS; Wu, ZL; Xie, HG; Xu, ZH; Zhou, HH1
Kobayashi, S; Kumai, T; Tanaka, M; Tateishi, T; Watanabe, M1
Boobis, AR; Edwards, RJ; Kappers, WA; Murray, S1
Reinen, J; Smit, M; Wenker, M1
Cruz, A; González-Curbelo, MÁ; León, J; Murcia, H1

Reviews

3 review(s) available for theophylline and troleandomycin

ArticleYear
Anti-inflammatory drugs in the treatment of allergic disease.
    The Medical clinics of North America, 1992, Volume: 76, Issue:4

    Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Auranofin; Bronchodilator Agents; Cromolyn Sodium; Drug Therapy, Combination; Glucocorticoids; Humans; Hydroxychloroquine; Immunoglobulins, Intravenous; Methotrexate; Quality of Life; Severity of Illness Index; Steroids; Theophylline; Troleandomycin

1992
[Macrolide antibiotics and their use in combined pharmacotherapy].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1989, Volume: 34, Issue:8

    Topics: Bacterial Infections; Depression, Chemical; Drug Interactions; Drug Therapy, Combination; Erythromycin; Humans; Metabolic Clearance Rate; Theophylline; Troleandomycin

1989
Pharmacokinetic drug interactions with macrolide antibiotics.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 15, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antipyrine; Carbamazepine; Drug Interactions; Ergot Alkaloids; Erythromycin; Humans; Kinetics; Pharmaceutical Preparations; Theophylline; Troleandomycin

1985

Trials

1 trial(s) available for theophylline and troleandomycin

ArticleYear
Effect of low-dose troleandomycin on theophylline clearance: implications for therapeutic drug monitoring.
    Pharmacotherapy, 1992, Volume: 12, Issue:2

    Topics: Adolescent; Asthma; Child; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Theophylline; Troleandomycin

1992

Other Studies

16 other study(ies) available for theophylline and troleandomycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Inhibition of theophylline clearance by troleandomycin.
    The Journal of allergy and clinical immunology, 1977, Volume: 59, Issue:3

    Topics: Drug Interactions; Humans; Theophylline; Troleandomycin

1977
TAO and theophylline.
    Hospital practice, 1978, Volume: 13, Issue:7

    Topics: Asthma; Drug Interactions; Humans; Theophylline; Troleandomycin

1978
Use of troleandomycin as a steroid-sparing agent in both asthma and chronic obstructive pulmonary disease.
    Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 1991, Volume: 2, Issue:3

    Topics: Adrenal Cortex Hormones; Aged; Asthma; Female; Humans; Lung Diseases, Obstructive; Male; Methylprednisolone; Middle Aged; Respiratory Function Tests; Spirometry; Substance-Related Disorders; Theophylline; Troleandomycin

1991
Application of theophylline metabolite assays to the exploration of liver microsome oxidative function in man.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:4

    Topics: Adult; Biotransformation; Cimetidine; Humans; Ketoconazole; Male; Microsomes, Liver; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Theophylline; Troleandomycin

1988
An improved protocol for the use of troleandomycin (TAO) in the treatment of steroid-requiring asthma.
    The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:1 Pt 1

    Topics: Adult; Aged; Asthma; Bronchospirometry; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methylprednisolone; Middle Aged; Substance Withdrawal Syndrome; Theophylline; Troleandomycin

1986
Depression of theophylline metabolism and elimination by troleandomycin and erythromycin.
    Biochemical pharmacology, 1981, Jun-01, Volume: 30, Issue:11

    Topics: Animals; Drug Interactions; Erythromycin; In Vitro Techniques; Male; Metabolic Clearance Rate; Microsomes, Liver; Rabbits; Theophylline; Troleandomycin; Uric Acid

1981
Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Cancer research, 1994, Jan-01, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aflatoxin B1; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Female; Humans; Hydroxylation; Lymphocytes; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases; Theophylline; Troleandomycin

1994
Clomipramine N-demethylation metabolism in human liver microsomes.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:5

    Topics: Adult; Clomipramine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; In Vitro Techniques; Mephenytoin; Methylation; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Troleandomycin

1998
Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Erythromycin; Half-Life; Haloperidol; Immune Sera; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Propionates; Quinine; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Theophylline; Troleandomycin

1999
Diazinon is activated by CYP2C19 in human liver.
    Toxicology and applied pharmacology, 2001, Nov-15, Volume: 177, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Diazinon; Dose-Response Relationship, Drug; Humans; Insecticides; Ketoconazole; Liver; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Recombinant Proteins; Theophylline; Troleandomycin

2001
Evaluation of Strategies for the Assessment of Drug-Drug Interactions Involving Cytochrome P450 Enzymes.
    European journal of drug metabolism and pharmacokinetics, 2018, Volume: 43, Issue:6

    Topics: Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Dihydralazine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Microsomes, Liver; Mifepristone; Paroxetine; Theophylline; Troleandomycin; Verapamil

2018
Study on the inhibitory effect of furafylline and troleandomycin in the 7-methoxyresorufin-O-demethylase and nifedipine oxidase activities in hepatic microsomes from four poultry species using high-performance liquid chromatography coupled with fluorescen
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-05, Volume: 164

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Microsomes, Liver; Nifedipine; Oxazines; Poultry; Theophylline; Troleandomycin

2019