theophylline and tretinoin

theophylline has been researched along with tretinoin in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199011 (27.50)18.7374
1990's11 (27.50)18.2507
2000's9 (22.50)29.6817
2010's9 (22.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Gudas, LJ; Rosenberg, RD; Soff, G; Weiler-Guettler, H; Yu, K1
Bottiroli, G; Colombo, A; Croce, AC; Mariani, M; Prosperi, E; Supino, R1
Abemayor, E; Lando, M; Sidell, N; Verity, MA1
Everett, MA; Fuller, BB; Iwata, M; Iwata, S1
Moore, SJ; Schiff, LJ1
Gudas, LJ; Stoner, CM1
Gudas, LJ; Roguska, MA; Wang, SY1
Haddox, MK; Maddox, AM1
Gudas, LJ; LaRosa, GJ; Wang, SY1
Gudas, LJ; Roguska, MA1
Bennett, TE; Caro, JF; Chaplinski, TJ1
Chaplinski, TJ; Niedel, JE1
Campisi, J; Gudas, LJ; Levine, RA; Wang, SY1
Gudas, LJ; Wang, SY2
Ademola, JI; Maibach, HI1
Hart, IR; Miller, N; Vile, RG1
Afink, GB; Bongcam-Rudloff, E; Joosten, PH; Mosselman, S; Nistér, M; Rademakers, PJ; Stassen, BH; Van Zoelen, EJ1
Balansky, RM; Blagoeva, PM; De Flora, S; Mircheva, ZI1
Kim, KW; Lee, HY; Lee, YH; Ryu, SH; Suh, PG1
Rogers, MB1
Shimada, T; Yamazaki, H1
Aller, P; de Blas, E; Galán, A; Garcia-Bermejo, L; Vilaboa, NE1
Daniel, MT; De Thé, H; Degos, L; Dombret, H; Gourmel, B; Guillemin, MC; Janin, A; Kogan, S; Lallemand-Breitenbach, V; Lanotte, M; Raffoux, E; Soilihi, H; Vitoux, D; Zhu, J1
Chambon, P; Faria, TN; Gudas, LJ; Zhuang, Y1
Abbruzzese, A; Beninati, S; Caraglia, M; Lentini, A; Marra, M1
Chen, S; Gudas, LJ; Sylvester, R; Tighe, AP; Xu, J1
Bruserud, O; Corbascio, M; Gjertsen, BT; Lassalle, P; Ryningen, A; Stapnes, C1
Bruserud, O; Fredly, H; Gjertsen, BT; Reikvam, H1
Bruserud, O; Døskeland, SO; Gausdal, G; Gjertsen, BT; Havemann, U; Herfindal, L; Kleppe, R; Lanotte, M; McCormack, E; Nguyen, E; Pendino, F; Rouhee, N; Schwede, F; Ségal-Bendirdjian, E; Skavland, J; Wergeland, A1

Reviews

2 review(s) available for theophylline and tretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Protein-polyamine conjugation by transglutaminase in cancer cell differentiation: review article.
    Amino acids, 2004, Volume: 26, Issue:4

    Topics: Animals; Cell Differentiation; Humans; Neoplasms; Polyamines; Proteins; Theophylline; Transglutaminases; Tretinoin; Xanthines

2004

Trials

1 trial(s) available for theophylline and tretinoin

ArticleYear
Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytokines; Female; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Palliative Care; Prognosis; Theophylline; Tretinoin; Tumor Cells, Cultured; Valproic Acid

2012

Other Studies

37 other study(ies) available for theophylline and tretinoin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Thrombomodulin gene regulation by cAMP and retinoic acid in F9 embryonal carcinoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-15, Volume: 89, Issue:6

    Topics: Animals; Base Sequence; Bucladesine; Cell Line; Cell Nucleus; Cyclic AMP; Gene Expression Regulation, Neoplastic; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptors, Cell Surface; Receptors, Thrombin; RNA, Neoplasm; Teratoma; Theophylline; Thrombin; Transcription, Genetic; Tretinoin

1992
Comparative studies on the effects of doxorubicin and differentiation inducing agents on B16 melanoma cells.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:4-5

    Topics: alpha-MSH; Animals; Cell Cycle; Cell Differentiation; Cell Survival; DNA, Neoplasm; Doxorubicin; Extracellular Space; Intracellular Fluid; Melanins; Melanoma, Experimental; Monophenol Monooxygenase; Theophylline; Tretinoin; Tumor Cells, Cultured

1992
Modulation of intracellular cyclic adenosine monophosphate levels and the differentiation response of human neuroblastoma cells.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Acetylcholinesterase; Alprostadil; Cell Differentiation; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Neuroblastoma; Norepinephrine; Theophylline; Tretinoin; Tumor Cells, Cultured

1990
Hormonal stimulation of tyrosinase activity in human foreskin organ cultures.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1990, Volume: 26, Issue:6

    Topics: Alprostadil; Black People; Bucladesine; Catechol Oxidase; Cholecalciferol; Histamine; Humans; Kinetics; Male; Melanocyte-Stimulating Hormones; Monophenol Monooxygenase; Organ Culture Techniques; Skin; Theophylline; Tretinoin; White People

1990
Effects of cyclic adenosine 3':5'-monophosphate-elevating agents and retinoic acid on differentiation in retinoid-deficient tracheal cultures.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1985, Volume: 21, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Cholera Toxin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Keratins; Phosphodiesterase Inhibitors; Retinoids; Theophylline; Trachea; Tretinoin

1985
Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells.
    Cancer research, 1989, Mar-15, Volume: 49, Issue:6

    Topics: Base Sequence; Bucladesine; Carrier Proteins; Cell Differentiation; Cloning, Molecular; DNA; Humans; Molecular Sequence Data; Receptors, Retinoic Acid; RNA, Messenger; Teratoma; Theophylline; Tretinoin

1989
Defective post-translational modification of collagen IV in a mutant F9 teratocarcinoma cell line is associated with delayed differentiation and growth arrest in response to retinoic acid.
    The Journal of biological chemistry, 1989, Sep-15, Volume: 264, Issue:26

    Topics: Animals; Ascorbic Acid; Bucladesine; Cell Differentiation; Cell Division; Cell Line; Collagen; Hydroxylation; Kinetics; Laminin; Mutation; Procollagen-Proline Dioxygenase; Protein Processing, Post-Translational; RNA, Messenger; Teratoma; Theophylline; Transcription, Genetic; Tretinoin

1989
Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells.
    Experimental cell biology, 1988, Volume: 56, Issue:1-2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Alprostadil; Bucladesine; Butyrates; Butyric Acid; Cell Division; Cyclic AMP; Dinoprostone; Enzyme Induction; Humans; Leukemia, Myeloid; Theophylline; Transglutaminases; Tretinoin; Tumor Cells, Cultured

1988
Molecular cloning of gene sequences transcriptionally regulated by retinoic acid and dibutyryl cyclic AMP in cultured mouse teratocarcinoma cells.
    Developmental biology, 1985, Volume: 107, Issue:1

    Topics: Animals; Bucladesine; Cell Differentiation; Cell Nucleus; Cells, Cultured; Cloning, Molecular; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes; Mice; Nucleic Acid Hybridization; Protein Biosynthesis; Teratoma; Theophylline; Transcription, Genetic; Tretinoin

1985
An increase in prolyl-4-hydroxylase activity occurs during the retinoic acid-induced differentiation of mouse teratocarcinoma stem cell lines F9 and P19.
    The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26

    Topics: Animals; Bucladesine; Cell Differentiation; Cell Line; Collagen; Endoderm; Fibroblasts; Immunosorbent Techniques; Kinetics; Mice; Procollagen-Proline Dioxygenase; Protein Processing, Post-Translational; Stem Cells; Teratoma; Theophylline; Tretinoin

1985
Alteration in insulin receptor expression accompanying differentiation of HL-60 leukemia cells.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Bucladesine; Cell Differentiation; Dimethyl Sulfoxide; Dinoprostone; Granulocytes; Humans; Leukemia, Experimental; Monocytes; Naphthol AS D Esterase; Nitroblue Tetrazolium; Prostaglandins E; Receptor, Insulin; Theophylline; Tretinoin; Vitamin D

1986
Cyclic AMP levels and cellular kinetics during maturation of human promyelocytic leukemia cells.
    Journal of leukocyte biology, 1986, Volume: 39, Issue:3

    Topics: Bucladesine; Cell Cycle; Cell Division; Cell Line; Cyclic AMP; Dimethyl Sulfoxide; Dinoprostone; Humans; Leukemia, Myeloid, Acute; Prostaglandins E; Protein Kinases; Theophylline; Tretinoin

1986
Butyrate inhibits the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells.
    Developmental biology, 1984, Volume: 105, Issue:2

    Topics: Acetates; Animals; Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Flow Cytometry; Mice; Plasminogen Activators; Teratoma; Theophylline; Tretinoin

1984
Isolation of cDNA clones specific for collagen IV and laminin from mouse teratocarcinoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:19

    Topics: Animals; Bucladesine; Cell Line; Cloning, Molecular; Collagen; DNA; Genes; Glycoproteins; Laminin; Mice; Neoplasms, Experimental; Nucleic Acid Hybridization; Protein Biosynthesis; RNA, Neoplasm; Teratoma; Theophylline; Tretinoin

1983
Selection and characterization of F9 teratocarcinoma stem cell mutants with altered responses to retinoic acid.
    The Journal of biological chemistry, 1984, May-10, Volume: 259, Issue:9

    Topics: Animals; Bucladesine; Cell Differentiation; Cell Division; Cell Line; Kinetics; Mice; Mutation; Neoplasm Proteins; Teratoma; Theophylline; Tretinoin

1984
Cutaneous metabolism and penetration of methoxypsoralen, betamethasone 17-valerate, retinoic acid, nitroglycerin and theophylline.
    Current problems in dermatology, 1995, Volume: 22

    Topics: Administration, Cutaneous; Adult; Betamethasone Valerate; Binding Sites; Biological Transport, Active; Decanoic Acids; Female; Glycerides; Humans; In Vitro Techniques; Liver; Male; Methoxsalen; Middle Aged; Nitroglycerin; Permeability; Propranolol; Skin; Skin Absorption; Theophylline; Tretinoin

1995
Effects of modulators of tyrosinase activity on expression of murine interleukin-2 cDNA driven by the tyrosinase promoter.
    Melanoma research, 1995, Volume: 5, Issue:2

    Topics: 3T3 Cells; Aminophylline; Animals; Consensus Sequence; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Interleukin-2; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Monophenol Monooxygenase; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Theophylline; Transfection; Tretinoin; Tumor Cells, Cultured; Up-Regulation

1995
Molecular cloning and functional characterization of the human platelet-derived growth factor alpha receptor gene promoter.
    Oncogene, 1995, Apr-20, Volume: 10, Issue:8

    Topics: Base Sequence; Bucladesine; Cloning, Molecular; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Platelet-Derived Growth Factor; TATA Box; Theophylline; Tretinoin

1995
Modulation of diethylnitrosamine carcinogenesis in rat liver and oesophagus.
    Journal of cellular biochemistry, 1994, Volume: 56, Issue:4

    Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Caffeine; Diethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Female; Liver Neoplasms, Experimental; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred Strains; Survival; Theophylline; Tretinoin

1994
Reduced expression of PLC-gamma during the differentiation of mouse F9 teratocarcinoma cells.
    Cancer letters, 1993, Volume: 68, Issue:2-3

    Topics: Animals; Blotting, Northern; Blotting, Western; Bucladesine; Cell Differentiation; Gene Expression Regulation, Neoplastic; Mice; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Teratoma; Theophylline; Tretinoin; Tumor Cells, Cultured

1993
Receptor-selective retinoids implicate retinoic acid receptor alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:1

    Topics: Animals; Benzoates; Blotting, Northern; Bone Morphogenetic Proteins; Bucladesine; Embryonal Carcinoma Stem Cells; Gene Expression Regulation, Neoplastic; Growth Substances; Mice; Neoplastic Stem Cells; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Theophylline; Tretinoin

1996
Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3

    Topics: Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Cholecalciferol; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Ethanolamines; Humans; Isoenzymes; Lauric Acids; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Omeprazole; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Paclitaxel; Prostaglandins; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline; Tretinoin; Warfarin; Xenobiotics

1999
Uncoupling of apoptosis and Jun/AP-1 activity in human promonocytic cells treated with DNA-damaging and stress-inducing agents.
    European journal of cell biology, 2000, Volume: 79, Issue:1

    Topics: Apoptosis; Cadmium Chloride; Camptothecin; Colforsin; Cyclic AMP; DNA Damage; Enzyme Inhibitors; Etoposide; Gene Expression; Heating; Humans; Monocytes; Proto-Oncogene Proteins c-jun; Theophylline; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transcription Factor AP-1; Tretinoin; U937 Cells; Uncoupling Agents

2000
In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia.
    The Journal of experimental medicine, 2002, Nov-18, Volume: 196, Issue:10

    Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Differentiation; Cell Division; Cyclic AMP; Leukemia, Promyelocytic, Acute; Mice; Mice, Transgenic; Oxides; Signal Transduction; Theophylline; Tretinoin; Tumor Cells, Cultured

2002
Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells.
    Molecular cancer research : MCR, 2003, Volume: 1, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antineoplastic Agents; Apoptosis Regulatory Proteins; Bucladesine; Carrier Proteins; Cell Differentiation; Cell Line, Tumor; Cytokines; Cytoskeletal Proteins; DNA-Binding Proteins; Forkhead Transcription Factors; GATA6 Transcription Factor; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glutamate Dehydrogenase; Glutathione Transferase; Homeodomain Proteins; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Midkine; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-myc; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Retinoic Acid; Teratocarcinoma; Theophylline; Trans-Activators; Transcription Factors; Transcriptional Activation; Tretinoin; Tumor Suppressor Proteins

2003
Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells.
    Journal of molecular biology, 2008, Mar-14, Volume: 377, Issue:1

    Topics: Animals; Binding Sites; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Embryonal Carcinoma Stem Cells; Gene Expression Regulation, Neoplastic; Genes, Reporter; Janus Kinase 2; Mercaptoethanol; Mice; Microarray Analysis; Neoplastic Stem Cells; Parathyroid Hormone; Peptides; Promoter Regions, Genetic; Proto-Oncogene Proteins pp60(c-src); Receptors, Retinoic Acid; RNA, Messenger; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Teratocarcinoma; Theophylline; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tretinoin

2008
A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid.
    Leukemia research, 2009, Volume: 33, Issue:6

    Topics: Aged; Aged, 80 and over; Blood Cell Count; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Proteoglycans; Risk Factors; Survival Analysis; Theophylline; Tretinoin; Valproic Acid

2009
Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis.
    Cell death & disease, 2013, Feb-28, Volume: 4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibiotics, Antineoplastic; Apoptosis; bcl-Associated Death Protein; Cell Line, Tumor; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Type I; Cyclic AMP-Dependent Protein Kinase Type II; Daunorubicin; Dinoprostone; Disease Progression; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; RNA Interference; RNA, Small Interfering; Theophylline; Transplantation, Heterologous; Tretinoin

2013