theophylline and thiophenes

theophylline has been researched along with thiophenes in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's6 (31.58)18.2507
2000's5 (26.32)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Frank, A1
Fryda-Kaurimsky, Z; Giesen, HK1
Cho, YW; Han, HC; Kuemmerle, HP; Oh, SY1
Bury, T; Corhay, JL; Louis, R; Radermecker, M1
Casadei, MC; Fregnan, GB; Guerzoni, P; Marchioni, CF; Moretti, M; Muratori, M; Scuri, R1
Borelli, S; Düngemann, H; Schiess, W1
Andriani, A; Chiappetta, MG; Fabiani, M1
Bowsher, RR; Cerimele, BJ; McNay, JL; Rowe, H; Schwertschlag, US1
Bruns, RF; Montamat, SC; Mudumbi, RV; Vestal, RE1
Richardt, G; Schreieck, J1
Duval, C; Galey, JB; Lagrange, A; Philippe, M; Régnier, M; Schmidt, R; Tuloup, R1
Choo, EF; Mayo, G; Shyr, Y; Sofowora, GG; Wilkinson, GR1
de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA1
Chapple, S; Collins, C; Fairman, DA1
Bergstrom, RF; Chappell, J; Hong, Q; Knadler, MP; Lobo, ED; Quinlan, T; Reddy, S; Ring, B1
Erve, JC; Vashishtha, SC; Wu, G1
Kang, HR; Kang, MG; Shim, EJ; Sohn, SW; Song, WJ1
Boico, A; Hamilton, K; Hanna, G; Irwin, D; Palmer, G; Piantadosi, CA; Radiloff, DR; Schroeder, T; Shan, S; Wu, C; Zhao, Y1

Reviews

2 review(s) available for theophylline and thiophenes

ArticleYear
[New aspects of long-term asthma therapy].
    Wiener medizinische Wochenschrift. Supplement, 1979, Volume: 54

    Topics: Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Allergens; Asthma; Chronic Disease; Cromolyn Sodium; Desensitization, Immunologic; Drug Therapy, Combination; Glucocorticoids; Humans; Parasympatholytics; Piperidines; Theophylline; Thiophenes

1979
[Platelet aggregation and antiaggregant drugs].
    Recenti progressi in medicina, 1982, Volume: 73, Issue:5

    Topics: Dipyridamole; Humans; Papaverine; Platelet Aggregation; Prostaglandins; Theophylline; Thiophenes; Thromboxane A2; Ticlopidine; Verapamil

1982

Trials

6 trial(s) available for theophylline and thiophenes

ArticleYear
[Ketotifen, a new prophylactic agent in asthma (author's transl)].
    Medizinische Klinik, 1979, Oct-19, Volume: 74, Issue:42

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Asthma; Child; Female; Humans; Ketotifen; Male; Middle Aged; Piperidines; Placebos; Theophylline; Thiophenes

1979
Comparative bronchodilatory activity of cetiedil citrate monohydrate, theophylline, orciprenaline and placebo in adult asthmatics.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:9

    Topics: Adolescent; Adult; Aged; Asthma; Azepines; Bronchodilator Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metaproterenol; Middle Aged; Placebos; Tachyphylaxis; Theophylline; Thiophenes

1978
Effects of erdosteine on sputum biochemical and rheologic properties: pharmacokinetics in chronic obstructive lung disease.
    Lung, 1990, Volume: 168, Issue:5

    Topics: Bronchitis; Chronic Disease; Double-Blind Method; Expectorants; Humans; Male; Rheology; Sputum; Theophylline; Thioglycolates; Thiophenes

1990
[Treatment of seasonal asthmatic symptoms. A multicentre trial to compare the effects of ketotifen and disodium cromoglycate (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Feb-29, Volume: 122, Issue:9

    Topics: Adrenergic beta-Agonists; Asthma; Beclomethasone; Bronchitis; Clinical Trials as Topic; Cromolyn Sodium; Histamine H1 Antagonists; Humans; Ketotifen; Piperidines; Random Allocation; Seasons; Spirometry; Theophylline; Thiophenes

1980
Effect of tibenelast (a phosphodiesterase inhibitor) and theophylline on isoproterenol-stimulated heart rate, cyclic AMP and norepinephrine levels.
    Pharmacology, 1993, Volume: 46, Issue:3

    Topics: Adult; Blood Pressure; Cyclic AMP; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Norepinephrine; Phosphodiesterase Inhibitors; Regression Analysis; Theophylline; Thiophenes

1993
In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine.
    Clinical pharmacokinetics, 2008, Volume: 47, Issue:3

    Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Interactions; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Infusions, Intravenous; Male; Microsomes, Liver; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Theophylline; Thiophenes

2008

Other Studies

11 other study(ies) available for theophylline and thiophenes

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
LY 186655, a phosphodiesterase inhibitor, inhibits histamine release from human basophils, lung and skin fragments.
    International journal of immunopharmacology, 1992, Volume: 14, Issue:2

    Topics: Adult; Basophils; Bronchodilator Agents; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lung; Skin; Theophylline; Thiophenes

1992
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2

    Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines

1993
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines

1999
Keratinocyte-melanocyte co-cultures and pigmented reconstructed human epidermis: models to study modulation of melanogenesis.
    Cellular and molecular biology (Noisy-le-Grand, France), 1999, Volume: 45, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Arbutin; Asian People; Benzofurans; Black People; Cells, Cultured; Coculture Techniques; Culture Media; Epidermal Cells; Ethnicity; Humans; Hydroquinones; Hydroxybenzoates; Indoles; Keratinocytes; Melanins; Melanocytes; Mice; Phenotype; Pyrones; Skin Pigmentation; Skin, Artificial; Theophylline; Thiophenes; Ultraviolet Rays; White People

1999
In vivo inhibition of human CYP1A2 activity by oltipraz.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:6

    Topics: Adult; Antineoplastic Agents; Caffeine; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Female; Humans; Male; Methylation; Pyrazines; Theophylline; Thiones; Thiophenes

2001
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines

2005
Progress curve analysis of CYP1A2 inhibition: a more informative approach to the assessment of mechanism-based inactivation?
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:12

    Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dihydralazine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Models, Biological; NADP; Paroxetine; Pyrazines; Resveratrol; Stilbenes; Theophylline; Thiones; Thiophenes

2007
Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs.
    Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8

    Topics: Animals; Binding Sites; Cytosol; Drug Design; Duloxetine Hydrochloride; Glutathione; Glutathione Transferase; Humans; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Quinidine; Rationalization; Rats; Structure-Activity Relationship; Theophylline; Thiophenes

2010
Severe drug hypersensitivity induced by erdosteine and doxofylline as confirmed by patch and lymphocyte transformation tests: a case report.
    Journal of investigational allergology & clinical immunology, 2012, Volume: 22, Issue:3

    Topics: Adult; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Patch Tests; Theophylline; Thioglycolates; Thiophenes

2012
The combination of theophylline and endothelin receptor antagonism improves exercise performance of rats under simulated high altitude.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Oct-15, Volume: 113, Issue:8

    Topics: Altitude; Animals; Arterial Pressure; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Endothelin Receptor Antagonists; Female; Heart Rate; Hemodynamics; Hemoglobins; Hypoxia; Isoxazoles; Oxygen; Phenylpropionates; Physical Conditioning, Animal; Piperazines; Pulmonary Artery; Purines; Pyridazines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Renal Circulation; Respiration; Sildenafil Citrate; Sulfones; Task Performance and Analysis; Theophylline; Thiophenes; Vasoconstriction

2012