theophylline has been researched along with theobromine in 529 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 276 (52.17) | 18.7374 |
| 1990's | 82 (15.50) | 18.2507 |
| 2000's | 78 (14.74) | 29.6817 |
| 2010's | 67 (12.67) | 24.3611 |
| 2020's | 26 (4.91) | 2.80 |
| Authors | Studies |
|---|---|
| Bridson, PK; Daly, JW; Hide, I | 1 |
| Daly, JW; Manning, M; Müller, CE; Shi, D | 1 |
| Cameron, IL; Lyles, MB; Rawls, HR | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Copits, B; Frausto, S; Gill, MB; Noguchi, K; Sakai, R; Sakurada, T; Shimamoto, K; Swanson, GT | 1 |
| Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
| Frantsuzova, SB | 2 |
| Collins, C; Richards, PT; Starmer, GA | 1 |
| Cardinali, DP | 1 |
| Boross, M; Holló, I | 1 |
| Bieck, P; Neuvonen, PJ; Vapaatalo, H; Westermann, E | 1 |
| Newburgh, RW; Tsuzuki, J | 1 |
| Hayashi, S; Sakaguchi, T | 1 |
| Davidson, D; Stallwood, GR | 1 |
| Kostellow, AB; Morrill, GA; Poupko, JM; Schatz, F | 1 |
| Butt, NM; Collier, HO; Cuthbert, NJ; Francis, DL; Saeed, SA | 1 |
| Porsche, E; Stefanovich, V | 1 |
| Stefanovich, V | 2 |
| Brodsky, B; Koup, JR | 1 |
| Myszka, A | 1 |
| Bada, HS; Khanna, NN; Somani, SM; Tin, AA | 1 |
| Shoyab, M | 1 |
| Cartheuser, C; Komarek, J | 1 |
| Nielsen-Kudsk, F; Pedersen, AK | 1 |
| Desiraju, RK; Mayock, RL; Sugita, ET | 1 |
| Göber, B; Kraft, R | 1 |
| Timson, J | 2 |
| Syed, IB | 1 |
| Kihlman, BA; Sturelid, S | 1 |
| Balagot, R; Ecanow, B; Takruri, H | 1 |
| Carotti, A; De Laurentis, N; Ferappi, M; Ottolino, S | 1 |
| Sved, S; Wilson, DL | 1 |
| Hossie, RD; McGilveray, IJ; Midha, KK; Sved, S | 1 |
| Amerson, E; Cook, CE; Kepler, JA; Myers, M; Taylor, GF; Twine, ME | 1 |
| Chae, YS; Shelver, WH | 1 |
| Chiou, WL; Peng, A; Peng, GW; Smith, V | 1 |
| Dechtiaruk, WA; Johnson, GF; Solomon, HM | 1 |
| Katz, ML; Kazmer, S; Mauer, I; Weinstein, D | 1 |
| Dechtiaruk, W; Johnson, GF; Solomon, HM | 1 |
| Hayashi, M; Kinoshita, M; Yamauchi, K | 1 |
| Arbin, A; Edlund, PO | 2 |
| Aeschbacher, HU; Würzner, HP | 1 |
| Wildanger, W | 1 |
| Frings, CS; Keefer, RC; Saloom, JM | 1 |
| Chapman, RA; Leoty, C | 1 |
| Davies, RJ | 1 |
| Johnson, GF; Least, CJ; Solomon, HM | 1 |
| Evenson, MA; Warren, BL | 1 |
| Jolicoeur, FB; Menard, D | 1 |
| Gonzalez, FJ; Gu, L; Kalow, W; Tang, BK | 1 |
| Fukao, K; Ishikawa, A; Iwasaki, Y; Misawa, S; Osada, A; Tanaka, E; Tsuji, K; Yamamoto, Y | 1 |
| Kaur, J; Sodhi, GS | 1 |
| Asahi, T; Kuribara, H; Tadokoro, S | 1 |
| Cayre, I; Frutos, G; González-Jimènez, J | 1 |
| Carnevale, A; Chiarotti, M; De Carolis, MP; De Giovanni, N; Muzii, U; Romagnoli, C; Tortorolo, G; Zecca, E | 1 |
| Blanchard, J; Shearer, LE; Weber, CW | 2 |
| Tanaka, E | 1 |
| Alderfer, JL; Brickmann, JA; Danilov, VI; Lautenschlager, P; Poltev, VI; Slyusarchuk, ON; Wollman, RM | 1 |
| Mante, S; Minneman, KP | 1 |
| Ferre, S; Guix, T; Jane, F; Limon, A; Parra, P | 1 |
| Musk, SR; Steel, GG | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H | 1 |
| Grimble, RF; Hart, AD | 2 |
| Kalhorn, TF; Lee, CA; Nelson, SD; Slattery, JT | 1 |
| Levy, G; Zhi, JG | 1 |
| Benowitz, NL; Brown, CR; Denaro, CP; Jacob, P; Wilson, M | 1 |
| Coffin, VL; Spealman, RD | 1 |
| Gilboe, DP | 1 |
| Holtzman, SG | 1 |
| Kunkel, SL; Larrick, J; Lynch, JP; Remick, DG; Spengler, RN; Strieter, RM; Ward, PA | 1 |
| Lupal'tsev, VI | 1 |
| Diaz, C; Gill, JM; Schiffman, SS | 1 |
| McPhee, MD; Whiting, SJ | 1 |
| El'skaia, IE; Neugodov, IuV; Popov, VV; Sokolov, GF | 1 |
| Chakraborty, J; Marks, V; Morgan, MY; Scott, NR; Stambuk, D | 1 |
| Hafkenscheid, JC; Hekster, YA; Nouws, JF; Vree, JB; Vree, TB | 1 |
| Morton, MR; Parish, RC; Spruill, WJ | 1 |
| Schiffman, SS; Warwick, ZS | 1 |
| Freyburger, G; Hammerschmidt, DE; Huh, PW; Kotasek, D; McCarthy, T; Vercellotti, GM | 1 |
| Beranger, S; Désiles, JP; Pascal, JC; Pinhas, H; Poizot, A | 1 |
| Albert, P; Alemany, J; de la Cruz, MJ; Roncero, I | 1 |
| Gerok, W; Haag, K; Holstege, A; Staiger, M | 1 |
| Halcák, L; Krizko, J; Oltman, M; Pechán, I; Pechánová, E; Zák, I | 1 |
| Cohen, IA; Converse-Swastek, K; Johnson, CE; Wesolowicz, L | 1 |
| Stavric, B | 1 |
| Abla, KA; Carney, JM; Daly, JW; Seale, TW; Shamim, MT | 1 |
| Pollard, I | 1 |
| Levy, G; Yasuhara, M | 1 |
| Gómez Reyes, D; Rojas Hidalgo, E | 1 |
| Bhargava, VO; Emodi, S; Hirate, J | 1 |
| Luke, DR; Rocci, ML; Saccar, CL | 1 |
| Pivovarova, EIa; Samsonov, AA; Vorob'ev, LP | 1 |
| Liu, DK; Owens, GF | 1 |
| Bantle, JA; Dawson, DA | 1 |
| Fischer, P; Gilhar, D; Kariv, R; Zbaida, S | 1 |
| Carney, JM; Logan, L; Seale, TW | 1 |
| Grome, JJ; Stefanovich, V | 1 |
| Ben-Zvi, Z; Gorodischer, R; Margalith, M; Warszawski, D; Yaari, A | 1 |
| Birkett, DJ; Lelo, A; Miners, JO; Robson, RA | 2 |
| Grgurinovich, N | 1 |
| Randall, JL; Scott, WJ; York, RG | 1 |
| Bucher, HU; Gautschi, K | 1 |
| Bhandal, AK; Brelvi, ZS; Studzinski, GP | 1 |
| Belinskaia, TF; Li, ED; Makoeva, LD; Margarian, AG; Sabaev, VV | 1 |
| Hodgkinson, AJ; Landon, J; Mahmod, SM; Rowell, FJ; Sidki, AM | 1 |
| Cummings, DM; Green, P; Rocci, ML; Saccar, C | 1 |
| Birkett, DJ; Lelo, A; Miners, JO; Robson, R | 1 |
| Carney, JM; Holloway, FA; Modrow, HE | 1 |
| Hurst, WJ; Martin, RA; Snyder, KP | 1 |
| Blanchard, J; Jonkman, JH; Sawers, SJ; Tang-Liu, DD | 1 |
| Belloto, RJ; Ochsner, AB; Sokoloski, TD | 1 |
| Karlaganis, G; Renner, E; Wahlländer, A | 1 |
| Gilbert, SG; Klassen, RD; Rice, DC; Stavric, B | 1 |
| Arima, M; Nakazawa, K; Tanaka, H | 1 |
| Cookman, JR; Hartley, R; Smith, IJ | 2 |
| Gardey, C; Okyayuz, GI; Rey, E; Thiroux, G; Ventura, MA | 1 |
| Becker, AB; Gillespie, CA; Simons, FE; Simons, KJ | 1 |
| Goshorn, C; Hinsvark, O; Park, YH | 1 |
| Bonati, M; Bortolotti, A; Gaspari, F; Jiritano, L | 1 |
| Nuzov, BG | 1 |
| Lichtenstein, LM | 1 |
| Mertz, DP | 1 |
| Jatlow, P | 1 |
| Lichtenstein, LM; Margolis, S | 1 |
| Varrone, S; Wolff, J | 1 |
| Bedford, JS; Bender, MA; Griggs, HG | 1 |
| Senanayake, UM; Wijesekera, RO | 1 |
| Bonting, SL; Ridderstap, AS | 1 |
| Case, RM; Scratcherd, T | 1 |
| Kurihara, K | 1 |
| Davis, RS; Hook, JB; McNeill, JH | 1 |
| Scott, WA; Solomon, B | 1 |
| Lackie, JM | 1 |
| Reiser, M; Stefanovich, V; von Pölnitz, M | 1 |
| Chapman, RA; Miller, DJ | 1 |
| Correze, C; Laudat, MH; Laudat, P; Nunez, J | 1 |
| Brenner, MJ; McNeill, JH; Muschek, LD | 1 |
| Goldman, JM; Hadley, ME | 1 |
| Blinks, JR; Bravený, P; Jewell, BR; Olson, CB | 1 |
| Beer, B; Chasin, M; Clody, DE; Vogel, JR | 1 |
| Nitz, RE; Oertel, S; Schraven, E | 1 |
| Greden, JF | 1 |
| Carrasco, L; Fernandez-Puentes, C; Vazquez, D | 1 |
| Amidon, GL | 1 |
| Czok, G | 1 |
| Lóránt, B | 1 |
| Fujii, T; Nishimura, H | 2 |
| Cornish, HH; Khanna, KL; Rao, GS | 2 |
| Fawaz, EN; Tejirian, A | 1 |
| Kakác, B; Sarsúnová, M; Semonský, M | 1 |
| Delitheos, AK; Karabali, SB; Varonos, DD | 1 |
| Campiglio, A | 1 |
| de Bree, PK; Haverkamp, J; van der Heiden, C; van Gennip, AH; Vliegenthart, JF; Wadman, SK | 1 |
| Borysiewicz, J; Porebska, A; Potec, Z | 1 |
| Bodem, G; Dengler, HJ; Ochs, H | 1 |
| Riegelman, S; Shah, VP | 1 |
| el-Darawy, ZI; Mobarak, ZM | 1 |
| Selchau, M | 1 |
| Nishikawa, H; Shio, I | 1 |
| Quadbeck, G; Tarragó-Humet, P | 1 |
| Chow, YP; Repta, AJ | 1 |
| Heftmann, E; Kurtzman, RH; Schwimmer, S | 1 |
| Marchenko, IZ; Zaslavskiĭ, ES | 1 |
| Brandes, R; Roth, HJ | 1 |
| Gräfe, G; Haller, R; Kleine, KH | 2 |
| Hüttenrauch, R; Schmeiss, U; Süss, W | 1 |
| Feigl, F; Goldstein, D; Libergott, E | 1 |
| Krupińska, J | 1 |
| Dumont, E; Kraus, L | 1 |
| Dumont, E; Kraus, LJ | 1 |
| Cohen, Y; Lesne, M; Valette, G; Wepierre, J | 1 |
| Leroux-Mamo, G; Pellerin, F | 1 |
| Franzke, C; Griehl, H; Grunert, S; Hildebrandt, R | 1 |
| Lehmann, G; Martinoid, P | 1 |
| Herz, A; Hess, R; Novoczek, G; Teschemacher, HJ | 1 |
| Mitoma, C; Neubauer, SE; Sorich, TJ | 1 |
| Franzke, C; Griehl, H; Grunert, KS; Hildebrandt, U | 1 |
| Ishida, T; Kojima, T | 1 |
| Arredondo, EG; Paul, WD; Routh, JI; Shane, NA | 1 |
| Lordi, NG; Paruta, AN; Sciarrone, BJ | 1 |
| Polánkay, V; Szász, G; Szászné Zacskó, M | 1 |
| Biedermann, J; Poethke, W | 1 |
| Boulvin, G; Chiurdoglu, G; Ottinger, R; Reisse, J | 1 |
| Gehl, A; Rink, M | 1 |
| Eckstein, M; Sulko, J | 1 |
| Goenechea, S; Paulus, W; Wienert, G | 1 |
| Reisch, J; Walker, H | 1 |
| Heunisch, E; Schmidt, G | 1 |
| Hedrick, CE; Koeppel, TA | 1 |
| Ecanow, B; Hughes, C | 1 |
| Fredholm, BB | 1 |
| Hirsh, K | 1 |
| Adewunmi, AI; Enwonwu, CO; Okolie, EE | 1 |
| Collier, HO; Cuthbert, NJ; Francis, DL | 1 |
| Herman, G; Mauduit, P; Rossignol, B | 1 |
| Kopf, GS; Lewis, CA; Vacquier, VD | 1 |
| Bourguet, J; Favard, P | 1 |
| Kimler, BF; Leeper, DB; Rowley, R; Schneiderman, MH; Snyder, MH | 1 |
| Butts-Lamb, P; Daly, JW; Padgett, W | 1 |
| Fredholm, BB; Lindgren, E | 1 |
| Matsudaira, H; Tanaka, O; Ueno, AM | 1 |
| Beyreder, J | 1 |
| Kaushal, B; Vashishat, RK | 1 |
| Hurst, WJ; Martin, RA; Tarka, SM | 1 |
| Branfman, AR; Callahan, MM; Yesair, DW | 1 |
| Spindel, E | 1 |
| Hurst, WJ; Tarka, SM | 1 |
| Spiller, MA | 1 |
| Fujii, T; Hanada, S; Nakatsuka, T | 1 |
| Arima, M; Iwasaki, S; Nakazawa, K; Tanaka, H | 1 |
| Albert, P; Alemany, J; Alvarez-Rementería, R; de la Cruz, MJ | 1 |
| Hawkins, DF; Mallett, KA; Meek, JH; Teare, AJ; Tebbutt, IH | 1 |
| Graham, HN | 1 |
| Bayton, E; Huddart, H; Shanklin, J | 1 |
| Chakraborty, J; Marks, V; Scott, NR | 1 |
| Sakabe, Y; Terada, H | 1 |
| Tarka, SM | 1 |
| Nomura, T | 1 |
| Shively, CA; Tarka, SM | 1 |
| Riegelman, S; Tang-Liu, DD; Williams, RL | 1 |
| Benignetti, G; Benvenuti, C; Fabbri, F | 1 |
| Kela, U; Trivedi, CP; Vijayvargiya, R | 1 |
| Anderson, KE; Buening, MK; Conney, AH; Fortner, JG; Kappas, A; Pantuck, CB; Pantuck, EJ | 1 |
| Kasabian, IN; Kukes, VG; Mamaeva, GG; Spesivtseva, VG | 1 |
| Bokuchava, MA; Skobeleva, NI | 1 |
| Houghton, E | 1 |
| Carney, JM | 1 |
| Kamimura, T; Mayahara, T; Ohata, H; Suzuki, K | 1 |
| Renner, HW | 1 |
| Assenza, SP; Brown, PR; Nakano, K | 1 |
| Bonati, M; Garattini, S; Latini, R; Marzi, E | 1 |
| Aizawa, Y; Kogo, H; Takeuchi, K | 2 |
| Adjei, A; Martin, A; Paruta, AN | 1 |
| Berlin, CM | 1 |
| Szeto, DW; Tse, FL | 1 |
| Deutsch, EA; Deutsch, ME | 1 |
| Aldridge, A; Neims, AH | 1 |
| Birkett, DJ; Foenander, T; Miners, JO; Wing, LM | 1 |
| Hartman, CA; Kucharczyk, N; Sofia, RD; Valia, KH | 1 |
| Coleman, AW; Coleman, JR | 1 |
| Domosławski, M; Kecik, D; Małkowska-Zwierz, W; Pawińska, M; Radomska, D; Retelska, D; Skopińska-Rózewska, E; Skopiński, P; Sobczyńska, A; Zukowska, M | 1 |
| Hirota, S; Iwazaki, A; Miyagishima, A; Nozawa, Y; Sadzuka, Y | 1 |
| Hara, K; Hieda, Y; Kageura, M; Kashimura, S | 2 |
| Hasegawa, R; Imaida, K; Ito, N; Ogiso, T; Shirai, T | 1 |
| Bump, EA; Coleman, CN; Macklis, RM; Palayoor, ST | 1 |
| Nascimento, ES; Ribeiro Neto, LM; Rieser, EM; Salvadori, MC | 1 |
| Kawauchi, S; Kosazuma, T | 1 |
| Chen, A; Lunte, CE | 1 |
| Cortijo, J; Morcillo, EJ; Orón, JD; Perpiñá, M | 1 |
| Dilly, KW; Donoso, P; Eisner, DA; Negretti, N; O'Neill, SC | 1 |
| de Carolis, AS; Pèzzola, A; Popoli, P | 1 |
| Edwards, G; Glazier, AP; Kokwaro, GO; Szwandt, IS; Ward, SA | 1 |
| Dollison, A; Espinosa, A; Ferreira, M; Jackson-Lewis, V; Jiang, H; Muthane, U; Parsons, B; Przedborski, S | 1 |
| Andersson, T; Birkett, DJ; McManus, ME; Miners, JO; Tassaneeyakul, W; Tukey, RH; Veronese, ME | 1 |
| Pollard, I; Wilkinson, JM | 1 |
| Frisella, WA; Sturm, CD; Yoon, KW | 1 |
| Wang, GF; Wu, YT; Zhang, SY | 1 |
| Kuribara, H | 1 |
| Agarwal, KC | 1 |
| Fukao, K; Ishikawa, A; Iwasaki, Y; Osada, A; Tanaka, E; Tsuji, K; Yamamoto, Y | 1 |
| Gerok, W; Holstege, A; Kurz, M; Weinbeck, M | 1 |
| Lupichuk, SM; Tabrizchi, R | 1 |
| Fink, JS; Pollack, AE | 1 |
| Hope, W; Rose'Meyer, RB; White, PJ | 1 |
| Shaban, M; Smith, RA; Stone, TW | 1 |
| Downing, J; Pollard, I; Scaramuzzi, R; Williamson, S | 1 |
| Norman, A; Rodopoulos, N | 1 |
| Abe, T; Gutterman, DD; Morgan, DA | 1 |
| Benchekroun, Y; Brazier, JL; Dautraix, S; Désage, M | 1 |
| Lunte, CE; Zhao, Y | 1 |
| Ishikura, C; Ishizuka, H; Kouno, Y; Samizo, K | 1 |
| Akaike, N; Kawa, K; Uneyama, H | 1 |
| Ji, T; Kessey, K; Mogul, DJ; Overstreet, LS; Trommer, BL | 1 |
| Cha, YN; Chung, WG | 1 |
| Chopde, CT; Ghosh, AK; Mandhane, SN | 1 |
| De Sarro, A; De Sarro, G; Grasso, S; Nava, F; Zappala, M | 1 |
| Matthews, NS; Mealey, KL; Peck, K; Taylor, TS | 1 |
| Barth, A; Janigro, D; Meno, JR; Newell, DW; Nguyen, LB; Wender, R; Winn, HR | 1 |
| Ashihara, H; Crozier, A; Ito, E | 1 |
| Doak, GJ; Reid, AR; Sawynok, J; Zarrindast, MR | 1 |
| Muszynski, MJ; Rajyaguru, JM | 1 |
| Diaz, MM; Lopez, A; Muñoz-Mingarro, D; Pozuelo, JM; Santa Maria, A | 1 |
| Abbruzzese, A; Autuori-Pezzoli, V; Beninati, S; Cardinali, M; Kleinman, HK; Lentini, A; Mattioli, P; Nicolini, L; Pietrini, A | 1 |
| Dormer, RL; McPherson, MA; Pereira, MM | 1 |
| Miura, T; Nakamura, K; Suzuki, I; Tatara, M | 1 |
| Dormer, RL; Lloyd Mills, C; McPherson, MA; Pereira, MM | 1 |
| Kaneko, S; Okada, M | 1 |
| Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K | 1 |
| Jodynis-Liebert, J; Matuszewska, A | 1 |
| Kaneko, S; Kawata, Y; Mizuno, K; Murakami, T; Okada, M; Wada, K | 1 |
| Jurklies, B; Kaelin-Lang, A; Niemeyer, G | 1 |
| Crosson, CE; Petrovich, M | 1 |
| Daly, JW; Shi, D | 1 |
| Das, M; Giri, AK; Pal, AK; Reddy, VG | 1 |
| Madhavi, YS; Madyastha, KM; Sridhar, GR; Vadiraja, BB | 1 |
| Dabek-Zlotorzynska, E; Lai, EP | 1 |
| Diao, L; Dunwiddie, TV; Jacobson, KA | 1 |
| Baer, MG; Mazzafera, P; Mohamed, RS; Saldaña, MD | 1 |
| Capasso, A | 1 |
| Horsmans, Y; Spatzenegger, M; Verbeeck, RK | 1 |
| Abdel Hadi, AA; Alkatheeri, NA; Almuhrami, AM; Barezaig, IM; Boni, NS; Elghazali, M; Wasfi, IA | 1 |
| Albani, F; Bonsi, P; Donadio, V; Liguori, R; Monari, L; Montagna, P; Vetrugno, R; Zele, I | 1 |
| Allen, DG; Hawke, TJ; Lindinger, MI | 1 |
| Kang, JH; Kang, JS; Kim, BS; Koh, HC; Lee, H; Om, SA; Shin, IC | 1 |
| Khan, SA; Means, C; Ooms, TG | 1 |
| Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM | 1 |
| Fredholm, BB; Irenius, E; Kull, B; Schulte, G | 1 |
| Caparros-Lefebvre, D; De Broucker, T; du Boisgueheneuc, F; Lannuzel, A | 1 |
| Boozer, CN; Chen, G; Heymsfield, SB; Nasser, JA; Solomon, JL; Wang, V | 1 |
| Kockler, DR; Lawson, CL; McCarthy, MW | 1 |
| Dorne, JL; Renwick, AG; Walton, K | 2 |
| Cannon, ME; Cooke, CT; McCarthy, JS | 1 |
| Andersen, T; Fogh, J | 1 |
| Hamann, M; Richter, A | 1 |
| Baroth, V; Breitkreutz, J; Gröning, R; Müller, RS | 1 |
| Shimada, H; Sugino, H; Tsuchimoto, K | 1 |
| Chen, QC; Wang, J | 1 |
| Arod, F; Dubler, E; Schmalle, HW; Schneider, A | 1 |
| Locquet, O; Magre, S; Pollard, I; Solvar, A | 1 |
| Bispo, MS; De Andrade, JB; De Oliveira, RF; Pinheiro, HL; Reis, JO; Veloso, MC | 1 |
| Arase, S; Fukui, K; Li, M; Marubayashi, A; Nakaya, Y | 1 |
| Fernández, PL; González, AG; Martín, MJ; Pablos, F | 1 |
| Brown, MP; Chou, CC; Gronwall, RR; Vickroy, TW; Webb, AI | 1 |
| Benowitz, NL; Haller, CA; Jacob, P | 1 |
| De Mello, FG; Leão-Ferreira, LR; Moussatché, N; Paes-De-Carvalho, R | 1 |
| El-sawy, KM; Hilal, R; Moustafa, H; Shalaby, SH | 1 |
| Andersson, A; Bodin, B; Carlsson, PO; Jansson, L; Källskog, O; Olsson, R | 1 |
| Gasior, M; Goldberg, SR; Jaszyna, M; Munzar, P; Witkin, JM | 1 |
| Chen, P; Ding, M; Xiao, S; Yang, H | 1 |
| Chou, CC; Vickroy, TW | 1 |
| Baer-Dubowska, W; Cichocki, M; Jodynis-Liebert, J; Matuszewska, A; Szaefer, H | 1 |
| Johnson, IM; Kumar, SG; Malathi, R | 2 |
| Chuan, D; Shao-Min, S; Yan-Li, W | 1 |
| Manesiotis, P; Theodoridis, G | 1 |
| BLAKE, M; HARRIS, LE | 2 |
| LILLY, DM; STERBENZ, FJ; TARANTOLA, V | 1 |
| JOHNSON, CC; POE, CF | 1 |
| HIGUCHI, T; LACH, JL | 1 |
| ISSANDOUCARLES, R; SEGONZAC, G; VINCENT, D | 1 |
| FLEISCHER, G | 1 |
| GIERTZ, H; OBERDORF, A; RUMMEL, W | 1 |
| BARTELS, M; BUBNOFF, M; HOCHREIN, H; SCHMID, E; TAUGNER, R; WALTZ, H; WETH, H | 1 |
| KUSCHINSKY, G; MUSCHOLL, E | 2 |
| DAVID, I | 1 |
| CHRISTMAN, AA; CORNISH, HH | 1 |
| BOLTON, S; GUTTMAN, D; HIGUCHI, T | 1 |
| BUSSE, W; HOFT, H; MARTINI, F; STOTTER, G | 1 |
| ROTH, HJ | 1 |
| KOGGE, W | 1 |
| WALTHER, H | 1 |
| CUGURRA, F; ECHINARD-GARIN, P | 1 |
| KALINOWSKA, ZE | 4 |
| SARSUNOVA, M; SCHWARZ, V | 1 |
| JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
| FUKUDA, H | 1 |
| UESUGI, Y | 1 |
| DONESON, IN; SHANKEL, DM | 1 |
| BIRON, A | 1 |
| DEMARTIIS, F; MARABELLI, M; TOFFOLI, F | 1 |
| HENDERSON, JF; MAZEL, P | 2 |
| JULICH, H | 1 |
| NOVOTNY, O | 1 |
| FIRTH, A; SMITH, WG | 1 |
| SIMON, MI; VANVUNAKIS, H | 1 |
| DIKSTEIN, S; SULMAN, FG | 1 |
| REICHERTZ, P | 1 |
| ALEXANDER, TG; MAIENTHAL, M | 1 |
| ALONSO, D; HARRIS, JB | 1 |
| KALINOWSKA, E | 1 |
| DHALA, S; RAJ, CV | 1 |
| SCHMID, E; TAUGNER, R; VON BUBNOFF, M | 1 |
| Aoshima, H; Hossain, SJ; Kiso, Y; Koda, H | 1 |
| LAGREU, R; VINCENT, D | 1 |
| HOCH, B; TOMICEK, O | 1 |
| FIELD, JB; GRAF, L; LINK, KP | 1 |
| Economou, A; Themelis, DG; Theodoridis, G; Tzanavaras, PD; Zacharis, CK | 1 |
| Flieger, J; Jodynis-Liebert, J; Juszczyk, J; Matuszewska, A | 1 |
| Ho, CM; Ho, ST; Peng, SC; Su, CK; Tsai, SK | 1 |
| Porter, BJ; Schantz, MM; Sharpless, KE; Thomas, JB; Yen, JH | 1 |
| Emara, S | 1 |
| SCHACK, JA; WAXLER, SH | 1 |
| GOFFART, M; GOUTIER, R | 1 |
| Gunasekaran, S; Ponnusamy, S; Sankari, G | 1 |
| Beijnen, JH; de Jonge, ME; den Hoed, R; Hendriks, VM; Huitema, AD; Sparidans, RW; van den Brink, W; van Ree, JM; Zandvliet, AS | 1 |
| Anstis, M; Edwards, HG; Munshi, T | 1 |
| Braasch, DA; Buddington, RK; Kimura, Y; Turner, JR | 1 |
| Miyazaki, K; Mochizuki, T; Sugawara, M; Takekuma, Y | 1 |
| Dong, C; Liu, DS; Shuang, SM; Wei, YL | 1 |
| Amado, AM; Ribeiro-Claro, PJ | 1 |
| Haskell, CF; Kennedy, DO; Milne, AL; Scholey, AB; Wesnes, KA | 1 |
| Heard, CM; Johnson, S; Moss, G; Thomas, CP | 1 |
| Belanger, K; Benowitz, NL; Bracken, MB; Grosso, LM; Holford, TR; Triche, EW | 1 |
| Arai, S; Horiuchi, Y; Inoue, H; Kobayashi-Hattori, K; Oishi, Y; Takita, T | 1 |
| Becker, SL; Callegari, E; Chen, C; Chen, X; Cianfrogna, J; Doran, AC; Doran, SD; Gibbs, JP; Hosea, N; Liu, J; Liu, X; Nelson, FR; Smith, BJ; Szewc, MA; Van Deusen, J | 1 |
| Bastos, JK; Freitas, LA; Pagliarussi, RS | 1 |
| Amado, AM; Nolasco, MM; Ribeiro-Claro, PJ | 1 |
| Fan, YJ; Lautt, WW; Ming, Z; Yang, X | 1 |
| Bonnaire, Y; Julliand, V; Lallemand, A; Respondek, F | 1 |
| Meidan, VM; Michniak, BB; Thakur, RA | 1 |
| Gartrell, BD; Reid, C | 1 |
| Feng, YQ; Lin, B; Ng, SC; Zheng, MM | 1 |
| Clark, RS; Dixon, CE; Gillespie, DG; Jackson, EK; Kochanek, PM; Puccio, AM; Sachse, KT; Wisniewski, SR | 1 |
| do Lago, CL; Nogueira, T | 1 |
| Kennedy, RA; Sriamornsak, P | 1 |
| Pawlukojc, A; Prager, M; Wischnewski, A; Wuttke, J | 1 |
| OSOL, A; TURNER, A | 1 |
| Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS | 1 |
| Boskovic, M; Injac, R; Karljikovic-Rajic, K; Prijatelj, M; Srdjenovic, B; Strukelj, B | 1 |
| Djordjevic-Milic, V; Grujic, N; Injac, R; Lepojevic, Z; Srdjenovic, B | 1 |
| Franco, R | 1 |
| Gressner, AM; Gressner, OA; Lahme, B; Siluschek, M | 1 |
| Kim, BS; Lee, HY | 1 |
| Capasso, A; Gallo, C | 1 |
| Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL | 1 |
| Gass, N; Kalinchuk, AV; Porkka-Heiskanen, T | 1 |
| Tang, BP; Wang, YQ; Zhang, HM | 1 |
| Hasegawa, T; Ishii, T; Nagata, T; Saijo, M; Takahashi, K | 1 |
| HEPPEL, LA; PEAKE, EG; PORTERFIELD, VT | 1 |
| Themelis, DG; Tzanavaras, PD; Zacharis, CK | 1 |
| Osowski, A; Pietrzak, M; Wieczorek, J; Wieczorek, Z | 1 |
| Arnaud, MJ | 1 |
| Louie, TM; Subramanian, M; Summers, RM; Yu, CL | 1 |
| Chester, TL; Stalcup, AM | 1 |
| Piriyaprasarth, S; Sriamornsak, P | 1 |
| Mokry, J; Nosalova, G | 1 |
| Bista, SR; Jahng, Y; Jeong, TC; Kang, MJ; Kang, W; Kim, E; Lee, SK; Noh, K; Seo, YM | 1 |
| Traş, B; Tumer, I; Uney, K | 1 |
| Geyer, T; Hillebrand, O; Licha, T; Nödler, K; Sauter, M | 1 |
| Duan, SM; Hu, ZA; Wang, HK; Xia, JX; Xiong, JX; Ye, JN | 1 |
| Schmidt, TC; Teutenberg, T; Wiese, S | 1 |
| Rangel, AO; Santos, JR | 1 |
| Gross, AS; McLachlan, AJ; Perera, V | 1 |
| Johnson, IM; Malathi, R; Prakash, H; Prathiba, J; Raghunathan, R | 1 |
| Dalonso, N; Petkowicz, CL | 1 |
| Bazinet, L; Blanchet, C; Bourdages, M; Bujold, E; Couillard, C; Dodin, S; Lemieux, S; Mogollon, JA; Noël, M | 1 |
| Chen, F; Lin, JM; Luo, C; Nakagawa, Y; Nakajima, H; Uchiyama, K; Zeng, H; Zhang, Y | 1 |
| Bae, SH; Bae, SK; Choi, EJ; Jang, SM; Kwon, MJ; Lee, SJ; Lee, YS; Park, JB; Zheng, YF | 1 |
| Kokot, S; Ni, Y; Xia, Z | 1 |
| Litvin, AA; Novitskaia, IaG; Viglinskaia, AO; Zherdev, VP | 1 |
| Andrisano, V; Fiori, J; Gotti, R; Guillarme, D; Naldi, M; Périat, A; Veuthey, JL | 1 |
| da Silva, JF; Gonçalves, JF; Kiyota, E; Mayer, JL; Mazzafera, P; Schimpl, FC | 1 |
| Ballanyi, K; Ciechanski, P; Mosca, EV; Roy, A; Scheibli, EC; Wilson, RJ | 1 |
| Camfield, DA; Maggini, S; Pipingas, A; Scholey, A; Silberstein, R; Stough, C; White, DJ | 1 |
| Ackermann, D; Ansermot, N; Bochud, M; Burnier, M; Eap, CB; Ehret, G; Gu, Y; Guessous, I; Martin, PY; Mohaupt, M; Paccaud, F; Pechère-Berstchi, A; Pechère-Bertschi, A; Ponte, B; Pruijm, M; Staessen, J; Vogt, B; Vuistiner, P | 1 |
| Ali, A; O'Donnell, JM; Rutherfurd-Markwick, KJ; Starck, C | 1 |
| Barbisan, F; Bochi, GV; Cargnin, LP; da Cruz, IB; da Silva, AR; Kober, H; Moresco, RN; Ribeiro, EE; Sangoi, MB; Tatsch, E; Torbitz, VD | 1 |
| Laing, T; Lake, BR; Mohamed, HA; Phillips, RM; Willans, CE | 1 |
| Kato, S; Nakajima, H; Rang, Y; Uchiyama, K; Zeng, H | 1 |
| Camandola, S; Cutler, RG; Edelhauser, MA; Malott, KF; Mattson, MP | 1 |
| Alharbi, O; Goodacre, R; Xu, Y | 1 |
| Campbell, SC; Clark, EA; Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Tak, C; Varner, MW; Yu, T | 1 |
| Cabral, FL; da Cruz, IB; da Silva, CB; Dos Santos, CB; Gonçalves, JF; Leal, DB; Lopes, ST; Machado, AK; Rezer, JF; Ruchel, JB; Schetinger, MR; Thorstenberg, ML | 1 |
| Gong, ZH; Huang, B; Jia, YX; Su, RB; Wang, ML; Wang, ZT; Yi, SP; Yu, G; Zhang, FY | 1 |
| Lopes, JA; Machado, S; Magalhães, LM; Páscoa, RN; Segundo, MA | 1 |
| Francini, A; Pierattini, EC; Raffaelli, A; Sebastiani, L | 1 |
| Bulatov, A; Kirsanov, D; Medinskaia, K; Nikolaeva, L; Timofeeva, I | 1 |
| Franco, R; Martínez-Pinilla, E; Oñatibia-Astibia, A | 2 |
| Zidek, W | 1 |
| Aswini, KK; Biju, VM; Vinu Mohan, AM | 1 |
| Islam, MM; Mitra, S; Rohman, MA; Sonu, VK | 1 |
| Alves, MG; Monteiro, JP; Oliveira, PF; Silva, BM | 1 |
| Düe, M; Kaiser, S; Kietzmann, M; Koppe, S; Machnik, M; Schänzer, W; Schenk, I; Thevis, M; Toutain, PL | 1 |
| Adamski, J; Artati, A; Bochud, M; Cornelis, MC; Eap, CB; Ehret, G; Friedrich, N; Ganna, A; Grabe, HJ; Guessous, I; Gustafsson, S; Homuth, G; Ingelsson, E; Kacprowski, T; Lind, L; Magnusson, PK; Mangino, M; Menni, C; Pedersen, NL; Pietzner, M; Pivin, E; Spector, TD; Suhre, K; Völzke, H | 1 |
| Abdalla, FH; Adefegha, SA; Braun, JBS; Castilhos, LG; da Silva, CB; de Oliveira, JS; Guedes Manzoni, A; Leal, DBR; Lopes, STA; Rubin, MA; Ruchel, JB; Signor, C; Trelles, K | 1 |
| Li, G; Row, KH; Wang, X | 1 |
| Canuto, KM; Coutinho, JP; da Silva, GS; de Brito, ES; de Jesus, RM; Nascimento, MM; Ribeiro, PRV; Zocolo, GJ | 1 |
| Oellig, C; Schunck, J; Schwack, W | 1 |
| Bender, M; Bunz, UHF; Hahn, S; Han, J; Seehafer, K; Wang, B | 1 |
| Chen, C; Feng, S; Que, L; Wang, W | 1 |
| Curulli, A; Marrosu, G; Petrucci, R; Zollo, G | 1 |
| Dong, ZB; Liang, YR; Lu, J; Ma, YX; Wu, HS; Wu, XH; Ye, JH; Zheng, XQ | 1 |
| Li, G; Row, KH | 1 |
| da Silva Morrone, M; de Mattos Pereira, L; Fonseca Moreira, JC; Giongo, A; Kich Grun, L; Kleber Silveira, A; Mautone Gomes, H; Moresco, KS; Pens Gelain, D; Rodrigues De Oliveira, R | 1 |
| Banipal, PK; Banipal, TS; Beri, A | 1 |
| Bartella, L; Di Donna, L; Mazzotti, F; Napoli, A; Siciliano, C; Sindona, G | 1 |
| Macedo, GA; Santana, ÁL | 1 |
| Liu, R; Shen, X; Sheng, L; Wu, F; Xu, H | 1 |
| Abdalla, FH; Bernardes, VM; Braun, JBS; Casali, EA; Castilhos, LG; da Cruz, IBM; de Andrade, CM; de Oliveira, JS; Leal, DBR; Manzoni, AG; Passos, DF; Ruchel, JB | 1 |
| Fávaro-Trindade, CS; Genovese, MI; Holkem, AT; Pinho, LS; Silva, MP; Thomazini, M | 1 |
| Coelho, M; Cunha, RA; Manadas, B; Mendes, VM; Tomé, AR | 1 |
| da Cruz, IBM; Dalcin, AJF; Gomes, P; Mitjans, M; Ourique, AF; Ribeiro, EE; Roggia, I; Vinardell, MP | 1 |
| Camiruaga, A; D'mello, VC; Fernández, JA; García, GA; Usabiaga, I; Wategaonkar, S | 1 |
| Ahmad, N; Ahmad, R; Al-Anaki, WS; Al-Jishi, F; Ismail, FA | 1 |
| de Camargo, AC; Pinaffi, ACDC; Sampaio, GR; Shahidi, F; Soares, MJ; Torres, EAFS | 1 |
| Hu, B; Huang, Z; Li, ZM; Wu, L; Yuan, ZC | 1 |
| Chagas Junior, GCA; Ferreira, NR; Gloria, MBA; Lopes, AS; Martins, LHDS | 1 |
| Chen, WL; Wu, SE | 1 |
| Foroughi, MM; Jahani, S; Nia, NA | 1 |
| Kennedy, M | 1 |
| Bachmann, CM; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA; Seyfried, M | 1 |
| Bachmann, CM; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA | 1 |
| Alexander-White, C; Bury, D; Clewell, HJ; Cronin, M; Desprez, B; Detroyer, A; Efremenko, A; Firman, J; Hack, E; Hewitt, NJ; Kenna, G; Klaric, M; Lester, C; Mahony, C; Ouedraogo, G; Paini, A; Schepky, A | 1 |
| Kan, K; Kimura, K; Sasamoto, T; Shindo, T; Tanaka, T | 1 |
| Ackermann, D; Ansermot, N; Bochud, M; Dhayat, NA; Eap, CB; Ehret, G; Estoppey-Younès, S; Guessous, I; Martin, PY; Melgarejo, JD; Petrovic, D; Ponte, B; Pruijm, M; Staessen, JA; Stringhini, S; Thijs, L; Vogt, B; Zhang, Z | 1 |
| Kertys, M; Kmeťová, K; Maráková, K; Mokrý, J; Pršo, K; Žideková, N | 1 |
| Celedón, JC; Forno, E; Han, YY | 1 |
| Bileck, A; Brunmair, J; Feuerstein, ML; Gerner, C; Gotsmy, M; Janker, L; Langbauer, C; Meier-Menches, SM; Neuditschko, B; Niederstaetter, L; Slany, A; Zanghellini, J | 1 |
| Guan, W; Mumford, SL; Polinski, KJ; Purdue-Smithe, A; Robinson, SL; Schisterman, EF; Schliep, KC; Silver, RM; Yeung, EH; Zhao, SK | 1 |
| Huang, PJ; Liu, J | 1 |
| Altikatoglu Yapaoz, M; Attar, A | 1 |
| Bachmann, CM; Griebsch, LV; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA; Pilz, SM; Theiss, EL; Winkler, J | 1 |
| Kinzig, M; Pietrzak-Fiećko, R; Purkiewicz, A; Sörgel, F | 1 |
| Dirikolu, L; Göktaş, EF; Güneş, E; Kabil, E; Yatanaslan, L | 1 |
| Chen, F; Cheng, R; Dai, HR; Ding, XS; Du, FF; Guo, HL; Hu, YH; Long, JY; Tian, M; Xia, Y; Xu, J | 1 |
| de Vries, MS; Ford, A; Williams, A | 1 |
25 review(s) available for theophylline and theobromine
| Article | Year |
|---|---|
Theobromine and theophylline.
Topics: Animals; Caffeine; Cells, Cultured; Chromosome Aberrations; Chromosomes; Drosophila; Escherichia coli; Humans; Mice; Mitosis; Mutagens; Mutation; Rats; Structure-Activity Relationship; Theobromine; Theophylline | 1975 |
The effects of caffeine.
Topics: Adult; Arteriosclerosis; Caffeine; Child, Preschool; Female; Humans; Hypersensitivity; Infant; Male; Middle Aged; Theobromine; Theophylline; Time Factors | 1976 |
Methylxanthines: toxicity to humans. 3. Theobromine, paraxanthine and the combined effects of methylxanthines.
Topics: Animals; Drug Synergism; Humans; Theobromine; Theophylline; Xanthines | 1988 |
[Nucleotide metabolism and gastric acid secretion].
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Caffeine; Cortisone; Cyclic AMP; Depression, Chemical; Dogs; Epinephrine; Gastric Juice; Gastric Mucosa; Glucocorticoids; Guinea Pigs; Histamine Release; Humans; Hydrazines; Imidazoles; In Vitro Techniques; Phentolamine; Phosphates; Phosphoric Monoester Hydrolases; Prednisolone; Propiophenones; Prostaglandins; Rabbits; Rats; Stimulation, Chemical; Sympatholytics; Theobromine; Theophylline; Vasodilator Agents | 1970 |
Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.
Topics: Alkylating Agents; Animals; Caffeine; Chromosome Aberrations; Cyanides; Cytarabine; Deoxyadenosines; DNA; DNA Repair; DNA Replication; DNA, Single-Stranded; Floxuridine; Hydroxyurea; Mitosis; Models, Biological; Mutagens; Radiation Genetics; Recombination, Genetic; Streptonigrin; Theobromine; Theophylline | 1974 |
[Diuretics. 47].
Topics: Acetazolamide; Carbonic Anhydrase Inhibitors; Chlormerodrin; Diuretics; Humans; Mannitol; Methazolamide; Organomercury Compounds; Pyrimidines; Sorbitol; Sulfonamides; Theobromine; Theophylline; Triazines; Urea; Xanthines | 1970 |
Effects of methylxanthines on skeletal muscle and on respiration.
Topics: Animals; Caffeine; Histamine Release; Muscle Contraction; Muscles; Respiration; Theobromine; Theophylline | 1984 |
Analytical methods for quantitation of methylxanthines.
Topics: Animals; Body Fluids; Caffeine; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Food Analysis; Humans; Methods; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 1984 |
Human disposition and some biochemical aspects of methylxanthines.
Topics: Caffeine; Contraceptives, Oral; Female; Humans; Intestinal Absorption; Kinetics; Male; Theobromine; Theophylline; Tissue Distribution | 1984 |
Action of the methylxanthines on the pituitary and pituitary-dependent hormones.
Topics: Adrenal Glands; Animals; Caffeine; Female; Growth Hormone; Humans; Male; Pituitary Gland; Prolactin; Theobromine; Theophylline; Thyroid Gland; Thyrotropin; Time Factors | 1984 |
Introduction to the chemistry, isolation, and biosynthesis of methylxanthines.
Topics: Cacao; Caffeine; Chemical Phenomena; Chemistry; Coffee; Tea; Theobromine; Theophylline | 1984 |
The chemical components of coffee.
Topics: Alkaloids; Caffeine; Carbohydrates; Coffee; Hydrocarbons; Lipids; Mycotoxins; Nitrogen; Pesticides; Phenols; Sulfur; Theobromine; Theophylline; Vitamins | 1984 |
The toxicology of cocoa and methylxanthines: a review of the literature.
Topics: Animals; Cacao; Caffeine; Diet; Female; Fetus; Fibrocystic Breast Disease; Humans; Mutagenicity Tests; Plants, Edible; Reproduction; Theobromine; Theophylline; Tissue Distribution; Xanthines | 1982 |
The biochemistry and technology of tea manufacture.
Topics: Alkaloids; Caffeine; Catechin; Fermentation; Food Handling; Food Technology; Hot Temperature; Nitrogen; Oils, Volatile; Plant Proteins; Species Specificity; Tannins; Tea; Theobromine; Theophylline | 1980 |
Uncertainty factors for chemical risk assessment: interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates.
Topics: Animals; Caffeine; Cytochrome P-450 CYP1A2; Dogs; Humans; Mice; Models, Biological; Pharmacokinetics; Probability; Rabbits; Rats; Reproducibility of Results; Risk Assessment; Species Specificity; Substrate Specificity; Theobromine; Theophylline | 2001 |
Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates.
Topics: Adult; Aged; Area Under Curve; Caffeine; Child; Cytochrome P-450 CYP1A2; Humans; Infant, Newborn; Models, Biological; Pharmacokinetics; Probability; Reproducibility of Results; Risk Assessment; Substrate Specificity; Theobromine; Theophylline; Warfarin | 2001 |
[PULMONARY EMPHYSEMA. (PATHOGENESIS, DIAGNOSIS, THERAPY)].
Topics: Acetazolamide; Blood Gas Analysis; Breathing Exercises; Bronchodilator Agents; Humans; Pulmonary Emphysema; Respiratory Function Tests; Theobromine; Theophylline | 1964 |
[Coffee and cancer].
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anticarcinogenic Agents; Caffeine; Cell Transformation, Neoplastic; Coffee; Female; Humans; Lymphocyte Activation; Male; Mice; Mice, Transgenic; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, Adenosine A2; Theobromine; Theophylline | 2008 |
Measurement of CYP1A2 activity: a focus on caffeine as a probe.
Topics: Animals; Breath Tests; Caffeine; Cytochrome P-450 CYP1A2; Humans; Saliva; Theobromine; Theophylline | 2012 |
The Role of Uric Acid and Methyl Derivatives in the Prevention of Age-Related Neurodegenerative Disorders.
Topics: Aging; Animals; Caffeine; Dietary Supplements; Humans; Mammals; Neurodegenerative Diseases; Theobromine; Theophylline; Uric Acid | 2015 |
The potential of methylxanthine-based therapies in pediatric respiratory tract diseases.
Topics: Adolescent; Apnea; Asthma; Bronchodilator Agents; Caffeine; Child; Child, Preschool; Cough; Humans; Infant; Infant, Newborn; Infant, Premature; Phosphodiesterase Inhibitors; Theobromine; Theophylline; Xanthines | 2016 |
Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks.
Topics: Animals; Cacao; Caffeine; Humans; Molecular Structure; Phytochemicals; Secondary Metabolism; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines | 2016 |
Health benefits of methylxanthines in neurodegenerative diseases.
Topics: Animals; Cacao; Caffeine; Coffee; Disease Models, Animal; Humans; Ilex paraguariensis; Meta-Analysis as Topic; Neurodegenerative Diseases; Plant Extracts; Theobromine; Theophylline; Xanthines | 2017 |
Effects of theophylline and theobromine on exercise performance and implications for competition sport: A systematic review.
Topics: Bronchodilator Agents; Exercise; Humans; Performance-Enhancing Substances; Sports; Theobromine; Theophylline | 2021 |
Methylxanthines and Neurodegenerative Diseases: An Update.
Topics: Alzheimer Disease; Animals; Caffeine; Coffee; Humans; Multiple Sclerosis; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Theobromine; Theophylline; Xanthines | 2021 |
18 trial(s) available for theophylline and theobromine
| Article | Year |
|---|---|
Dose-dependency of caffeine metabolism with repeated dosing.
Topics: Adult; Caffeine; Cardiovascular Diseases; Coffee; Dose-Response Relationship, Drug; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Random Allocation; Risk Factors; Theobromine; Theophylline | 1990 |
[Teonicol and trental in the treatment of duodenal ulcer].
Topics: Adolescent; Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Duodenal Ulcer; Humans; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate | 1986 |
Comparison of the urinary metabolite profile of caffeine in young and elderly males.
Topics: Adult; Aged; Aging; Caffeine; Glomerular Filtration Rate; Humans; Male; Random Allocation; Theobromine; Theophylline | 1985 |
The bronchodilator effect and pharmacokinetics of theobromine in young patients with asthma.
Topics: Adolescent; Asthma; Child; Female; Forced Expiratory Volume; Humans; Kinetics; Male; Theobromine; Theophylline; Time Factors | 1985 |
[Bioavailability of digoxin in fixed combinations (author's transl)].
Topics: Administration, Oral; Adult; Amines; Analysis of Variance; Coumarins; Digoxin; Drug Combinations; Esters; Ethers; Female; Glycolates; Humans; Ketones; Male; Radioimmunoassay; Theobromine; Theophylline; Time Factors | 1974 |
Use of pentoxifylline in the treatment of acute cerebrovascular insufficiency.
Topics: Acute Disease; Benzamides; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hexobendine; Humans; Male; Pentoxifylline; Retrospective Studies; Theobromine; Theophylline | 1983 |
[Use of trental and complamine in the microcirculatory disorders of diabetes mellitus].
Topics: Adult; Aged; Blood; Clinical Trials as Topic; Diabetic Angiopathies; Diabetic Nephropathies; Female; Humans; Hypoglycemic Agents; Male; Microcirculation; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate | 1980 |
An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial.
Topics: Adult; Anthropometry; Blood Pressure; Caffeine; Dietary Supplements; Double-Blind Method; Drug Combinations; Drugs, Chinese Herbal; Female; Heart Rate; Humans; Male; Middle Aged; Obesity; Theobromine; Theophylline; Triglycerides; Weight Loss | 2001 |
Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients.
Topics: Caffeine; Double-Blind Method; Female; Gastric Emptying; Humans; Ilex paraguariensis; Male; Obesity; Phytotherapy; Plant Extracts; Plant Leaves; Seeds; Stomach; Theobromine; Theophylline; Time Factors; Turnera; Ultrasonography; Weight Loss | 2001 |
Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use.
Topics: Adult; Affect; Blood Pressure; Caffeine; Central Nervous System Stimulants; Emotions; Ephedra; Ephedra sinica; Ephedrine; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Heart Rate; Humans; Male; Phenylpropanolamine; Pilot Projects; Reference Values; Theobromine; Theophylline | 2002 |
Serum metabolite/caffeine ratios as a test for liver function.
Topics: Adult; Caffeine; Female; Hepatitis, Chronic; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Theobromine; Theophylline | 2004 |
Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine.
Topics: Administration, Inhalation; Administration, Oral; Biological Availability; Caffeine; Central Nervous System Stimulants; Drug Combinations; Drug Interactions; Half-Life; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Methadone; Narcotics; Population; Theobromine; Theophylline | 2005 |
A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guaraná in humans.
Topics: Administration, Oral; Adult; Affect; Attention; Caffeine; Capsules; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Memory; Psychotropic Drugs; Reference Values; Theobromine; Theophylline | 2007 |
Urinary excretion of dietary contaminants in horses.
Topics: Animals; Atropine; Bufotenin; Caffeine; Cross-Over Studies; Doping in Sports; Dose-Response Relationship, Drug; Food Contamination; Horses; Morphine; N,N-Dimethyltryptamine; Physical Conditioning, Animal; Scopolamine; Theobromine; Theophylline | 2006 |
Blood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trial.
Topics: Adolescent; Adult; Biomarkers; Blood Pressure; Cacao; Caffeine; Candy; Catechin; Double-Blind Method; Endothelium; Energy Intake; Feasibility Studies; Female; Healthy Volunteers; Humans; Patient Compliance; Pilot Projects; Polyphenols; Pregnancy; Theobromine; Theophylline; Young Adult | 2013 |
The effect of a single dose of multivitamin and mineral combinations with and without guaraná on functional brain activity during a continuous performance task.
Topics: Adolescent; Adult; Attention; Brain; Caffeine; Calcium, Dietary; Cognition; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Evoked Potentials, Visual; Follow-Up Studies; Functional Neuroimaging; Humans; Magnesium; Neurons; Performance-Enhancing Substances; Theobromine; Theophylline; Vitamins; Young Adult; Zinc | 2017 |
The Effect of Caffeine Ingestion during Evening Exercise on Subsequent Sleep Quality in Females.
Topics: Adult; Caffeine; Contraceptives, Oral; Cross-Over Studies; Double-Blind Method; Exercise; Exercise Test; Female; Humans; Sleep; Theobromine; Theophylline; Young Adult | 2015 |
Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites.
Topics: Adult; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Pregnancy; Pregnancy Trimesters; Theobromine; Theophylline; Young Adult | 2016 |
486 other study(ies) available for theophylline and theobromine
| Article | Year |
|---|---|
Imidazodiazepinediones: a new class of adenosine receptor antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Azepines; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Imidazoles; In Vitro Techniques; Molecular Conformation; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1990 |
Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
Topics: Animals; Brain; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline; Xanthines | 1993 |
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
Topics: Acridine Orange; Intercalating Agents; Methylation; Nonlinear Dynamics; Spectrophotometry; Structure-Activity Relationship; Xanthines | 2001 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Novel N-methylated 8-oxoisoguanines from Pacific sponges with diverse neuroactivities.
Topics: Action Potentials; Animals; Behavior, Animal; Cells, Cultured; Convulsants; Crystallography, X-Ray; Excitatory Postsynaptic Potentials; Guanine; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neurons; Palau; Patch-Clamp Techniques; Porifera; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Synaptic Transmission | 2010 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
[Level of nicotinamide coenzymes in the myocardium of rats during the effects of methylxanthines (theophylline, theobromine, caffeine) and catecholamines].
Topics: Animals; Caffeine; Epinephrine; Female; Heart; Isoproterenol; Male; Myocardium; NAD; NADP; Norepinephrine; Rats; Stimulation, Chemical; Theobromine; Theophylline | 1975 |
Caffeine-phenacetin interaction in the rat: effects on absorption, metabolism and locomotor activity.
Topics: Animals; Caffeine; Dextroamphetamine; Drug Interactions; Female; Intestinal Absorption; Motor Activity; Phenacetin; Rats; Theobromine; Theophylline; Time Factors | 1977 |
Effects of pentoxifylline and theophylline on neurotransmitter uptake and release by synaptosome-rich homogenates of the rat hypothalamus.
Topics: Animals; Bucladesine; Dopamine; Glutamates; Hypothalamus; Male; Neurotransmitter Agents; Norepinephrine; Pentoxifylline; Potassium; Rats; Serotonin; Synaptosomes; Theobromine; Theophylline; Xanthines | 1977 |
Influence of methyl xanthine treatment on calcitonin effect.
Topics: Androgens; Animals; Caffeine; Calcitonin; Calcium; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Time Factors; Xanthines | 1978 |
Actions of various methylxanthines and papaverine on the synthesis of corticosterone in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Bucladesine; Caffeine; Corticosterone; Depression, Chemical; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Papaverine; Phosphodiesterase Inhibitors; Rats; Theobromine; Theophylline; Time Factors | 1975 |
Inhibition of 5'-nucleotidase in rat brain by methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Caffeine; Nucleotidases; Rats; Theobromine; Theophylline; Xanthines | 1975 |
Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine (BL 191). II. Effect of BL 191 on lipolysis in rat epididymal adipose tissue.
Topics: Adipose Tissue; Animals; Cyclic AMP; Epinephrine; Fatty Acids, Nonesterified; Kinetics; Lipid Metabolism; Male; Phosphoric Diester Hydrolases; Rats; Theobromine; Theophylline; Xanthines | 1975 |
Responses of proliferating cells to methylxanthines. Reversal of effect by colchicine.
Topics: Aminophylline; Bucladesine; Caffeine; Cell Division; Cell Nucleus; Colchicine; Mitotic Index; Plant Cells; Theobromine; Theophylline; Xanthines | 1977 |
Changes in cyclic AMP levels in the amphibian ovarian follicle following progesterone induction of meiotic maturation. Effect of phosphodiesterase inhibitors and exogenous calcium on germinal vesicle breakdown.
Topics: Animals; Anura; Bucladesine; Caffeine; Calcium; Cyclic AMP; Female; Fertilization; Leucine; Meiosis; Ovarian Follicle; Phosphodiesterase Inhibitors; Progesterone; Rana pipiens; Theobromine; Theophylline | 1977 |
Mechanism of quasi-morphine withdrawal behaviour induced by methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Humans; Male; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Xanthines | 1979 |
[The influence of pentifylline and theophylline on reaction kinetics on rat brain ATPase stimulatable by catecholamines (author's transl)].
Topics: Adenosine Triphosphatases; Animals; Brain; Catecholamines; Drug Interactions; Female; Kinetics; Magnesium; Rats; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Theobromine; Theophylline | 1979 |
Cyclic 3',5'-adenosine monophosphate phosphodiesterase (cAMP PDE) and cyclic 3',5'-guanosine monophosphate phosphodiesterase (cGMP PDE) in microvessels isolated from bovine cortex.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Calcium; Cattle; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Imidazoles; Magnesium; Microcirculation; Theobromine; Theophylline | 1979 |
Comparison of homogeneous enzyme immunoassay and high-pressure liquid chromatography for the determination of theophylline concentration in serum.
Topics: Caffeine; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Theobromine; Theophylline | 1978 |
[Cosaldon retard in the treatment of optic neuritis and macular degeneration].
Topics: Aged; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Humans; Macular Degeneration; Male; Nicotinic Acids; Optic Neuritis; Theobromine; Theophylline; Visual Acuity; Visual Fields; Xanthinol Niacinate | 1979 |
Interconversion of theophylline and caffeine in newborn infants.
Topics: Age Factors; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theobromine; Theophylline; Xanthines | 1979 |
The stimulation of murine hepatic aryl hydrocarbon hydroxylase activity in vitro by caffeine.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Binding Sites; Caffeine; DNA; Hypoxanthines; In Vitro Techniques; Mice; Microsomes, Liver; Stimulation, Chemical; Theobromine; Theophylline; Uric Acid | 1979 |
[Effect of pentoxifylline, xanthinol nicotinate and theophylline on the cardiovascular system, myocardial dynamics and left ventricular contractility of the dog in short-system, experiments].
Topics: Animals; Dogs; Hemodynamics; Myocardial Contraction; Myocardium; Oxygen Consumption; Pentoxifylline; Theobromine; Theophylline; Time Factors; Xanthinol Niacinate | 1977 |
Simultaneous and specific determination of proxyphylline, theophylline and other xanthine derivatives in serum by high pressure liquid chromatography.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Theobromine; Theophylline; Xanthines | 1978 |
Determination of theophylline and its metabolites by liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Saliva; Theobromine; Theophylline; Uric Acid; Xanthines | 1977 |
[Mass spectrophotometric degradation of theophyllidine, caffeidine and the methylxanthines caffeine, theophylline and theobromine].
Topics: Caffeine; Chemical Phenomena; Chemistry; Drug Stability; Mass Spectrometry; Theobromine; Theophylline | 1978 |
Enhancement by methylated oxypurines of the frequency of induced chromosomal aberrations.
Topics: Animals; Caffeine; Cell Line; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cricetinae; Drug Synergism; Methylation; Mutation; Plants; Purines; Theobromine; Theophylline; Thiotepa; Uric Acid | 1975 |
Water as a nonpolar partition medium.
Topics: Animals; Barbiturates; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Colon; Intestinal Absorption; Rats; Solubility; Theobromine; Theophylline; Water | 1977 |
[Theophylline and theobromine derivatives of nitrogen heterocyclic compounds].
Topics: Heterocyclic Compounds; Indicators and Reagents; Nitrogen; Theobromine; Theophylline | 1977 |
Simultaneous assay of the methylxanthine metabolites of caffeine in plasma by high performance liquid chromatography.
Topics: Caffeine; Chromatography, Liquid; Humans; Theobromine; Theophylline; Xanthines | 1977 |
High performance liquid chromatographic and mass spectrometric identification of dimethylxanthine metabolites of caffeine in human plasma.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Theobromine; Theophylline; Xanthines | 1977 |
Theophylline radioimmunoassay: synthesis of antigen and characterization of antiserum.
Topics: Animals; Antibody Formation; Caffeine; Cross Reactions; Female; Immune Sera; Male; Microchemistry; Rabbits; Radioimmunoassay; Saliva; Serum Albumin, Bovine; Theobromine; Theophylline | 1976 |
Quantitative determination of theophylline in pharmaceutical dosage forms by differential spectrophotometry.
Topics: Amobarbital; Caffeine; Capsules; Chemical Phenomena; Chemistry; Drug Stability; Ephedrine; Methods; Spectrophotometry, Ultraviolet; Tablets; Theobromine; Theophylline | 1976 |
A rapid and sensitive method for determination of theophylline in plasma and saliva by high pressure liquid chromatography.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Methods; Saliva; Theobromine; Theophylline | 1976 |
Gas-chromatographic determination of theophylline in human serum and saliva.
Topics: Asthma; Child; Chromatography, Gas; Evaluation Studies as Topic; Humans; Methods; Microchemistry; Phenobarbital; Saliva; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Ultrasonics | 1975 |
The effect of methylxanthines on chromosomes of human lyphocytes in culture.
Topics: Caffeine; Cells, Cultured; Chromosomes; Humans; Lymphocytes; Mitosis; Mutagens; Theobromine; Theophylline; Time Factors; Xanthines | 1975 |
Letter: faster gas-chromatographic procedure for theophylline.
Topics: Chromatography, Gas; Humans; Phenobarbital; Theobromine; Theophylline; Xanthines | 1975 |
N-alkylation of purines with alkyl esters of phosphorus oxy acids.
Topics: Adenine; Alkylation; Chemical Phenomena; Chemistry; Esters; Phosphoric Acids; Purines; Theobromine; Theophylline; Xanthines | 1975 |
Determination of theophylline in biological material by means of electron capture gas chromatography.
Topics: Animals; Brain Chemistry; Chromatography, Gas; In Vitro Techniques; Methods; Rats; Theobromine; Theophylline | 1975 |
Effect of methylxanthines on hepatic microsomal enzymes in the rat.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Caffeine; Male; Microsomes, Liver; Nitroanisole O-Demethylase; Proteins; Rats; Theobromine; Theophylline; Time Factors | 1975 |
[Separation of caffeine, theophylline and theobromine with assistance from high pressure liquid chromatography].
Topics: Caffeine; Chromatography, High Pressure Liquid; Theobromine; Theophylline | 1975 |
A rapid and precise method for determining theophylline in serum.
Topics: Barbiturates; Caffeine; Humans; Methods; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 1975 |
Which of caffeine's chemical relatives are able to evoke contractures in mammalian heart?
Topics: Animals; Caffeine; Guinea Pigs; Heart Ventricles; Imidazoles; In Vitro Techniques; Myocardial Contraction; Rats; Structure-Activity Relationship; Temperature; Theobromine; Theophylline; Ventricular Function; Xanthines | 1975 |
Complexes of poly(adenylic acid) with complementary monomers.
Topics: Anti-Bacterial Agents; Binding Sites; Hypoxanthines; Kinetics; Nucleic Acid Conformation; Optical Rotation; Optical Rotatory Dispersion; Poly A; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Theobromine; Theophylline; Xanthines | 1976 |
Gas-chromatographic micro-scale procedure for theophylline, with use of a nitrogen-sensitive detector.
Topics: Caffeine; Chromatography, Gas; Humans; Microchemistry; Nitrogen; Phenobarbital; Saliva; Theobromine; Theophylline; Xanthines | 1976 |
Serum theophylline analysis by high-pressure liquid chromatography.
Topics: Caffeine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Microchemistry; Structure-Activity Relationship; Theobromine; Theophylline | 1976 |
Evidence for involvement of A1 adenosine receptors in neurotensin-induced hypothermia.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Hypothermia; Male; Neurotensin; Purinergic Antagonists; Rats; Theobromine; Theophylline | 1992 |
Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
Topics: Biotransformation; Caffeine; Cloning, Molecular; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; DNA; Gene Expression; Humans; Oxidoreductases; Oxidoreductases, N-Demethylating; Theobromine; Theophylline; Vaccinia virus | 1992 |
A simple useful method for the determination of hepatic function in patients with liver cirrhosis using caffeine and its three major dimethylmetabolites.
Topics: Adult; Caffeine; Evaluation Studies as Topic; Female; Humans; Liver; Liver Cirrhosis; Male; Methods; Middle Aged; Oxidation-Reduction; Theobromine; Theophylline | 1992 |
Diuretic activity of organomercury (II) complexes of theophylline and theobromine.
Topics: Animals; Diuresis; Diuretics; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Organomercury Compounds; Rats; Rats, Sprague-Dawley; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Theobromine; Theophylline | 1992 |
Behavioral evaluation of psycho-pharmacological and psychotoxic actions of methylxanthines by ambulatory activity and discrete avoidance in mice.
Topics: Animals; Avoidance Learning; Caffeine; Male; Methamphetamine; Mice; Motor Activity; Theobromine; Theophylline | 1992 |
Fluorescence quenching of human serum albumin by xanthines.
Topics: Caffeine; Humans; Serum Albumin; Spectrometry, Fluorescence; Temperature; Theobromine; Theophylline; Thermodynamics; Tryptophan; Xanthines | 1992 |
Effectiveness and side effects of two different doses of caffeine in preventing apnea in premature infants.
Topics: Apnea; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theobromine; Theophylline | 1992 |
Methylxanthine levels in breast milk of lactating women of different ethnic and socioeconomic classes.
Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Diet Records; Educational Status; Female; Hispanic or Latino; Humans; Milk, Human; Socioeconomic Factors; Theobromine; Theophylline; White People | 1992 |
Simultaneous determination of caffeine and its primary demethylated metabolites in human plasma by high-performance liquid chromatography.
Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Theobromine; Theophylline | 1992 |
A Monte Carlo simulation of hydration of xanthine-derivatives and their stacked forms.
Topics: Caffeine; Molecular Conformation; Monte Carlo Method; Theobromine; Theophylline; Thermodynamics; Water; Xanthines | 1992 |
Caffeine inhibits forskolin-stimulated cyclic AMP accumulation in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Caffeine; Cerebral Cortex; Colforsin; Cyclic AMP; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1990 |
High-performance liquid chromatographic separation of caffeine, theophylline, theobromine and paraxanthine in rat brain and serum.
Topics: Animals; Brain Chemistry; Caffeine; Chromatography, High Pressure Liquid; Male; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 1991 |
Override of the radiation-induced mitotic block in human tumour cells by methylxanthines and its relationship to the potentiation of cytotoxicity.
Topics: Caffeine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; In Vitro Techniques; Mitosis; Theobromine; Theophylline; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xanthines | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
The effect of methylxanthines on milk volume and composition, and growth of rat pups.
Topics: Animals; Animals, Newborn; Body Weight; Caffeine; Fatty Acids; Female; Lactation; Milk; Pregnancy; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Time Factors; Xanthines | 1990 |
Effect of methylxanthines on lactational performance of rats.
Topics: Animals; Animals, Newborn; Body Weight; Caffeine; Drinking; Eating; Female; Lactation; Pregnancy; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1990 |
HPLC analysis of methylxanthines in human breast milk.
Topics: Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Milk, Human; Temperature; Theobromine; Theophylline; Xanthines | 1990 |
Effect of methylxanthines on acetaminophen hepatotoxicity in various induction states.
Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Body Temperature; Caffeine; Glutathione; Imines; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1990 |
Effect of chronic caffeine administration on theophylline concentrations required to produce seizures in rats.
Topics: Animals; Caffeine; Drug Interactions; Drug Tolerance; Kinetics; Male; Rats; Rats, Inbred Lew; Seizures; Theobromine; Theophylline | 1990 |
Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Chlordiazepoxide; Conditioning, Psychological; Male; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Saimiri; Theobromine; Theophylline; Xanthines | 1985 |
The mechanism of caffeine-enhanced glucose stimulation of liver glycogen synthase phosphatase activity.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Drug Interactions; Glucose; Glucose-6-Phosphate; Glucosephosphates; Liver; Male; Phosphoprotein Phosphatases; Rats; Structure-Activity Relationship; Theobromine; Theophylline; Time Factors; Xanthine; Xanthines | 1986 |
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1986 |
Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Assay; Bucladesine; Cyclic AMP; Dinoprostone; Lipopolysaccharides; Mice; Pentoxifylline; Theobromine; Theophylline; Tumor Necrosis Factor-alpha | 1988 |
[Use of a combination of rheopolyglucin, complamin and trental in the complex treatment of acute postoperative pancreatitis].
Topics: Acute Disease; Dextrans; Drug Therapy, Combination; Humans; Pancreatitis; Pentoxifylline; Platelet Aggregation Inhibitors; Postoperative Complications; Theobromine; Theophylline; Xanthinol Niacinate | 1988 |
Methyl xanthines enhance taste: evidence for modulation of taste by adenosine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adult; Animals; Caffeine; Female; Humans; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Taste; Theobromine; Theophylline; Xanthines | 1985 |
The effect of adenosine and adenosine analogues on methylxanthine-induced hypercalciuria in the rat.
Topics: Adenosine; Animals; Body Weight; Caffeine; Calcium; Diet; Diuresis; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1989 |
[The onset of circulatory venous gangrene of the arm and its successful treatment by thrombolysis].
Topics: Adult; Arm; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gangrene; Heparin; Humans; Infusions, Intravenous; Pentoxifylline; Subclavian Vein; Theobromine; Theophylline; Thrombolytic Therapy; Thrombosis; Xanthinol Niacinate | 1989 |
The pharmacokinetics of caffeine and its dimethylxanthine metabolites in patients with chronic liver disease.
Topics: Adult; Aged; Caffeine; Female; Half-Life; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Saliva; Theobromine; Theophylline | 1989 |
Excretion and metabolism of a series of xanthines by the turtle Pseudemys scripta elegans.
Topics: Animals; Caffeine; Theobromine; Theophylline; Turtles; Uric Acid; Xanthine; Xanthines | 1989 |
Lack of theophylline assay interference from pentoxifylline and its metabolites.
Topics: Aged; Fluorescence Polarization; Humans; Pentoxifylline; Theobromine; Theophylline | 1989 |
Use of flavor-amplified foods to improve nutritional status in elderly patients.
Topics: Aged; Aging; Amiloride; Bretylium Tosylate; Caffeine; Flavoring Agents; Humans; Inosine; Inosine Monophosphate; Nutritional Status; Smell; Taste; Theobromine; Theophylline | 1989 |
Pentoxifylline inhibits granulocyte and platelet function, including granulocyte priming by platelet activating factor.
Topics: Blood Platelets; Cell Adhesion; Cell Aggregation; Chemotaxis, Leukocyte; Endothelium, Vascular; Granulocytes; Humans; Pentoxifylline; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Superoxides; Theobromine; Theophylline; Thrombin | 1988 |
New antihistaminic theophylline or theobromine derivatives.
Topics: Acetylcholine; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Histamine H1 Antagonists; Male; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains; Serotonin Antagonists; Skin Tests; Structure-Activity Relationship; Theobromine; Theophylline | 1985 |
Changes induced by caffeine, theophylline and theobromine on calcium uptake, respiration and ATP levels in rat-liver mitochondria.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Female; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1988 |
Correlation of caffeine elimination and Child's classification in liver cirrhosis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Caffeine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Liver Cirrhosis; Male; Middle Aged; Theobromine; Theophylline | 1989 |
[Methylxanthines and enzymes which degrade adenine nucleotides].
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Deaminase; Animals; Brain; Caffeine; Female; Guinea Pigs; Liver; Male; Nucleotidases; Purine-Nucleoside Phosphorylase; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1986 |
Effect of pentoxifylline and its metabolites on three theophylline assays.
Topics: Adult; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Male; Pentoxifylline; Theobromine; Theophylline | 1988 |
Xanthine derivatives: could a further study of the mechanisms of action yield new therapeutic agents?
Topics: Caffeine; Humans; Theobromine; Theophylline | 1988 |
3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred DBA; Motor Activity; Reference Values; Theobromine; Theophylline | 1988 |
Increases in plasma concentrations of steroids in the rat after the administration of caffeine: comparison with plasma disposition of caffeine.
Topics: Animals; Caffeine; Corticosterone; Liver; Male; Progesterone; Rats; Rats, Inbred Strains; Sodium; Stress, Physiological; Testosterone; Theobromine; Theophylline | 1988 |
Rapid development of functional tolerance to caffeine-induced seizures in rats.
Topics: Animals; Brain; Caffeine; Drug Tolerance; Kinetics; Male; Rats; Rats, Inbred Lew; Seizures; Theobromine; Theophylline | 1988 |
[Therapeutic results with xanthine derivatives in the intermittent claudication syndrome in diabetic patients].
Topics: Adult; Aged; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Intermittent Claudication; Male; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate | 1988 |
Quantitation of acetaminophen and its metabolites in rat plasma after a toxic dose.
Topics: Acetaminophen; Animals; Chromatography, Liquid; Injections, Intravenous; Rats; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 1988 |
Pharmacokinetics of pentoxifylline during concomitant theophylline administration to rats.
Topics: Animals; Drug Interactions; Male; Pentoxifylline; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1987 |
Methylxanthine treatment of rats reduces 2,5-oligoadenylate synthesis in liver nuclei.
Topics: 2',5'-Oligoadenylate Synthetase; Animals; Caffeine; Cell Nucleus; Liver; Male; Poly I-C; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1987 |
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, Nonmammalian; Emetine; Fluorouracil; Hydroxyurea; Theobromine; Theophylline; Xanthines; Xenopus laevis | 1987 |
Reactions of theophylline, theobromine and caffeine with Fenton's reagent--simulation of hepatic metabolism.
Topics: Caffeine; Hydrogen Peroxide; Hydroxylation; Iron; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Theobromine; Theophylline | 1987 |
Inherent differences in sensitivity to methylxanthines among inbred mice.
Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Drug Resistance; Mice; Mice, Inbred Strains; Motor Activity; Species Specificity; Theobromine; Theophylline; Time Factors; Xanthines | 1986 |
Differential effects of methylxanthines on local cerebral blood flow and glucose utilization in the conscious rat.
Topics: Animals; Blood Flow Velocity; Brain; Caffeine; Cerebrovascular Circulation; Glucose; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1986 |
Changes in theophylline metabolism during postnatal development in rat liver slices.
Topics: Allopurinol; Animals; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Liver; Proadifen; Rats; Theobromine; Theophylline | 1986 |
Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man.
Topics: Adult; Caffeine; Humans; Kinetics; Male; Theobromine; Theophylline | 1986 |
Quantitative assessment of caffeine partial clearances in man.
Topics: Adult; Caffeine; Humans; Kinetics; Male; Theobromine; Theophylline | 1986 |
Simple and sensitive method for the simultaneous determination of enprofylline, theobromine, paraxanthine, theophylline and caffeine using high-performance liquid chromatography.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Theobromine; Theophylline; Xanthines | 1986 |
Teratogenicity of paraxanthine (1,7-dimethylxanthine) in C57BL/6J mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cleft Palate; Dose-Response Relationship, Drug; Female; Limb Deformities, Congenital; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Pregnancy; Theobromine; Theophylline | 1986 |
[Detection of caffeine, theophylline and theobromine in the umbilical cord blood and breast milk].
Topics: Caffeine; Female; Fetal Blood; Humans; Infant, Premature; Kinetics; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Theobromine; Theophylline | 1985 |
Cell cycle sensitivity of HL-60 cells to the differentiation-inducing effects of 1-alpha,25-dihydroxyvitamin D3.
Topics: Calcitriol; Cell Cycle; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Theobromine; Theophylline; Thymidine; Time Factors; Tritium | 1985 |
[Effect of beta-adrenergic blockaders and trental on plasma levels of renin and aldosterone in healthy persons during antiorthostatic hypokinesia].
Topics: Adult; Aldosterone; Humans; Immobilization; Male; Pentoxifylline; Posture; Propranolol; Renin; Theobromine; Theophylline; Time Factors | 1985 |
Direct determination of theophylline in serum by fluoroimmunoassay using highly specific antibodies.
Topics: Animals; Antibody Specificity; Caffeine; Cross Reactions; Female; Fluorescein; Fluoresceins; Fluorescent Antibody Technique; Humans; Rabbits; Sheep; Theobromine; Theophylline; Xanthines | 1985 |
Interference potential of pentoxifylline and its major metabolite with theophylline assays.
Topics: Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Pentoxifylline; Theobromine; Theophylline | 1985 |
Assessment of caffeine exposure: caffeine content of beverages, caffeine intake, and plasma concentrations of methylxanthines.
Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Coffee; Female; Humans; Male; Tea; Theobromine; Theophylline; Xanthines | 1986 |
Discriminative stimulus properties of methylxanthines and their metabolites in rats.
Topics: Animals; Caffeine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1985 |
Use of microbore high-performance liquid chromatography for the determination of caffeine, theobromine and theophylline in cocoa.
Topics: Cacao; Caffeine; Chromatography, High Pressure Liquid; Theobromine; Theophylline | 1985 |
Prediction of xanthine solubilities using statistical techniques.
Topics: Caffeine; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Solubility; Solvents; Statistics as Topic; Theobromine; Theophylline; Xanthines | 1985 |
High-performance liquid chromatographic determination of dimethylxanthine metabolites of caffeine in human plasma.
Topics: Ammonium Sulfate; Caffeine; Chromatography, High Pressure Liquid; Humans; Liver Diseases; Theobromine; Theophylline | 1985 |
The fate of chronically consumed caffeine in the monkey (Macaca fascicularis).
Topics: Animals; Biotransformation; Body Weight; Caffeine; Chromatography, High Pressure Liquid; Eating; Female; Macaca fascicularis; Milk; Theobromine; Theophylline; Time Factors | 1985 |
The effect of caffeine ingestion on pharmacokinetics of caffeine and its metabolites after a single administration in pregnant rats.
Topics: Administration, Oral; Animals; Caffeine; Female; Injections, Intravenous; Kinetics; Pregnancy; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1985 |
Improved high-performance liquid chromatographic method for the simultaneous determination of caffeine and its N-demethylated metabolites in plasma using solid-phase extraction.
Topics: Caffeine; Chromatography, High Pressure Liquid; Dealkylation; Humans; Serum Albumin, Bovine; Theobromine; Theophylline; Xanthines | 1985 |
Studies on methyl-xanthines in intact and hypophysectomised rats: differences in pharmacokinetics and adrenocortical response.
Topics: Adrenal Cortex; Animals; Blood Proteins; Caffeine; Corticosterone; Half-Life; Hematocrit; Hypophysectomy; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1985 |
Two high-performance liquid chromatographic methods for quantitation of theophylline in plasma.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 1985 |
Caffeine disposition after oral administration to pregnant rats.
Topics: Administration, Oral; Amniotic Fluid; Animals; Caffeine; Female; Fetus; Pregnancy; Rats; Theobromine; Theophylline; Time Factors | 1985 |
[Use of teonikol and trental in the combined treatment of patients with suppurative surgical infection and concomitant diabetes mellitus].
Topics: Chronic Disease; Conjunctiva; Diabetes Mellitus; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Pentoxifylline; Plethysmography, Impedance; Surgical Wound Infection; Theobromine; Theophylline; Time Factors; Xanthinol Niacinate | 1985 |
The role of cyclic AMP in inhibiting the IgE-mediated release of histamine.
Topics: Butyrates; Cyclic AMP; Depression, Chemical; Drug Synergism; Edetic Acid; Epinephrine; Hexoses; Histamine Release; Humans; Hypersensitivity, Immediate; Immunoglobulin E; In Vitro Techniques; Isoproterenol; Leukocytes; Propranolol; Theobromine; Theophylline | 1971 |
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences.
Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin | 1973 |
Histamine release in vitro: inhibition by catecholamines and methylxanthines.
Topics: Cyclic AMP; Depression, Chemical; Drug Synergism; Epinephrine; Histamine Release; Humans; Isoproterenol; Leukocytes; Theobromine; Theophylline | 1968 |
The methyl xanthines--a new class of goitrogens.
Topics: Aminophylline; Animals; Antithyroid Agents; Blood Proteins; Caffeine; Cyclic AMP; Drug Synergism; Goiter; Hypophysectomy; In Vitro Techniques; Iodine; Male; Propylthiouracil; Protein Binding; Rats; Theobromine; Theophylline; Thyroid Gland | 1969 |
A rapid micro-method for the separation, identification and estimation of the purine bases: caffeine, theobromine and theophylline.
Topics: Caffeine; Chromatography, Thin Layer; Methods; Silicon Dioxide; Theobromine; Theophylline | 1968 |
Cyclic AMP and enzyme secretion by the isolated rabbit pancreas.
Topics: Acetylcholine; Adenine Nucleotides; Amylases; Animals; Cholecystokinin; Cyclic AMP; Pancreas; Pancreatic Juice; Proteins; Rabbits; Theobromine; Theophylline | 1969 |
The actions of dibutyryl cyclic adenosine 3',5'-monophosphate and methyl xanthines on pancreatic exocrine secretion.
Topics: Animals; Caffeine; Cats; Cholecystokinin; Cyclic AMP; Drug Synergism; In Vitro Techniques; Pancreas; Pancreatic Juice; Secretin; Stimulation, Chemical; Theobromine; Theophylline; Water; Xanthines | 1972 |
Inhibition of cyclic 3',5'-nucleotide phosphodiesterase in bovine taste papillae by bitter taste stimuli.
Topics: Animals; Bacitracin; Binding, Competitive; Caffeine; Cattle; Cyclic AMP; Epithelium; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Quinine; Strychnine; Taste; Taste Buds; Theobromine; Theophylline | 1972 |
Inhibition and enhancement of the noradrenaline constrictor response by methylxanthines.
Topics: Animals; Caffeine; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Mesenteric Arteries; Norepinephrine; Perfusion; Phosphodiesterase Inhibitors; Theobromine; Theophylline | 1973 |
Cyclic 3',5'-AMP phosphodiesterase of Neurospora crassa.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Caffeine; Cations, Divalent; Chromatography, Paper; Cyclic AMP; Edetic Acid; Histamine; Imidazoles; Kinetics; Neurospora; Neurospora crassa; Phosphates; Phosphoric Diester Hydrolases; Solubility; Theobromine; Theophylline; Time Factors; Tritium | 1973 |
The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.
Topics: Adenine; Adenosine; Animals; Bucladesine; Caffeine; Cell Aggregation; Colchicine; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Leukocytes; Nucleotides, Cyclic; Rabbits; Stimulation, Chemical; Theobromine; Theophylline; Vinblastine; Xanthines | 1974 |
Inhibition of various cyclic AMP phosphodiesterases by pentifylline and theophylline.
Topics: Analysis of Variance; Animals; Aorta; Brain; Bronchi; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Kidney; Kinetics; Liver; Male; Myocardium; Phosphodiesterase Inhibitors; Rats; Serum Albumin; Theobromine; Theophylline; Tritium | 1974 |
Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart.
Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Heart Atria; Histamine; Histidine; Hydrogen-Ion Concentration; Hypoxanthines; Imidazoles; In Vitro Techniques; Naphazoline; Phentolamine; Pilocarpine; Potassium; Pyridines; Rana pipiens; Solutions; Structure-Activity Relationship; Surface Tension; Theobromine; Theophylline; Tolazoline; Xanthines | 1974 |
Hormone-dependent lipolysis in fat-cells from thyroidectomized rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Caffeine; Cell Membrane; Cyclic AMP; Epinephrine; Fluorides; Glucagon; In Vitro Techniques; Lipid Metabolism; Protein Kinases; Rats; Stimulation, Chemical; Theobromine; Theophylline; Thyroid Gland; Thyroid Hormones; Thyroidectomy | 1974 |
Interaction of four methylxanthine compounds and norepinephrine on cardiac phosphorylase activation and cardiac contractility.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Female; Guinea Pigs; Male; Myocardial Contraction; Myocardium; Nicotine; Norepinephrine; Papaverine; Phosphodiesterase Inhibitors; Phosphorylases; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines | 1973 |
Cyclic AMP and adrenergic receptors in melanophore responses to methylxanthines.
Topics: Adenine Nucleotides; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Caffeine; Catecholamines; Chromatophores; Cyclic AMP; Female; In Vitro Techniques; Lizards; Male; Melanocyte-Stimulating Hormones; Sensory Receptor Cells; Stimulation, Chemical; Theobromine; Theophylline; Xanthines | 1970 |
Influence of caffeine and other methylxanthines on mechanical properties of isolated mammalian heart muscle. Evidence for a dual mechanism of action.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atropine; Caffeine; Calcium; Calcium Isotopes; Cats; Electric Stimulation; Heart; In Vitro Techniques; Isoproterenol; Muscle Contraction; Norepinephrine; Papillary Muscles; Procaine; Propranolol; Reserpine; Strontium; Strontium Isotopes; Theobromine; Theophylline; Time Factors | 1972 |
Cyclic adenosine monophosphate phosphodiesterase in brain: effect on anxiety.
Topics: Animals; Anxiety; Barbiturates; Brain; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Cyclic AMP; Diazepam; Humans; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Punishment; Rats; Theobromine; Theophylline; Tranquilizing Agents | 1972 |
[The effect on glucose transport in the heart and brain of xanthine derivatives].
Topics: Adenylyl Cyclases; Animals; Biological Transport; Blood Glucose; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Glucagon; Glucose; Heart; Insulin; Male; Mice; Myocardium; Salicylates; Theobromine; Theophylline; Time Factors; Xanthines | 1974 |
Anxiety or caffeinism: a diagnostic dilemma.
Topics: Adult; Anxiety Disorders; Cacao; Caffeine; Carbonated Beverages; Coffee; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Humans; Male; Psychoses, Substance-Induced; Substance Withdrawal Syndrome; Substance-Related Disorders; Tea; Theobromine; Theophylline | 1974 |
The enhancement of polypeptide synthesis in mammalian systems by methylxanthines.
Topics: Aminophylline; Anemia; Animals; Caffeine; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Hydroxyapatites; Peptide Biosynthesis; Peptide Elongation Factors; Phenylalanine; Phenylhydrazines; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Transfer; Theobromine; Theophylline; Time Factors; Ultracentrifugation | 1974 |
Structure and reactivity of theobrominate and theophyllinate complexes with methyl trans-cinnamate.
Topics: Chemical Phenomena; Chemistry; Cinnamates; Ligands; Mathematics; Models, Chemical; Molecular Conformation; Structure-Activity Relationship; Theobromine; Theophylline; Thermodynamics | 1974 |
[Biological effectiveness of methyl xanthines in cocoa products].
Topics: Animals; Bronchi; Cacao; Caffeine; Cardiovascular System; Central Nervous System; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Drug Synergism; Female; Humans; Kidney; Mice; Muscles; Receptors, Drug; Theobromine; Theophylline; Xanthines | 1974 |
[The effect of methylxanthines on catecholamine and adenylate nucleotide concentration in rat myocardium].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Inosine; Inosine Nucleotides; Myocardium; Phosphorus; Rats; Stimulation, Chemical; Strophanthins; Theobromine; Theophylline; Tyramine; Xanthines | 1974 |
[Determination of substances of biochemical and bromatological interest by complex formation with heterpoly acids. The thermic properties of the complex salts].
Topics: Caffeine; Chemical Phenomena; Chemistry; Cytosine; Hot Temperature; Molybdenum; Phosphates; Phosphotungstic Acid; Silicon; Theobromine; Theophylline; Thiamine; Tungsten; Xanthines | 1974 |
Fetal hypoproteinemia associated with generalized edema caused by administration of methyl xanthines to the rat during late pregnancy.
Topics: Animals; Blood Proteins; Body Water; Body Weight; Caffeine; Edema; Female; Fetal Diseases; Fetus; Gestational Age; Hypoproteinemia; Methylation; Pregnancy; Rats; Theobromine; Theophylline; Xanthines | 1973 |
Metabolism of caffeine- 3 H in the rat.
Topics: Animals; Caffeine; Chromatography, Thin Layer; Male; Mass Spectrometry; Rats; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Tritium; Uric Acid; Xanthines | 1972 |
Inhibition of alkaline phosphatase by theophylline in vitro.
Topics: Alkaline Phosphatase; Animals; Caffeine; Cattle; Humans; In Vitro Techniques; Intestines; Phosphoenolpyruvate; Spectrophotometry; Theobromine; Theophylline | 1972 |
Mass spectrometric identification of methylxanthines and methyluric acids, the possible metabolites of caffeine.
Topics: Caffeine; Chromatography, Gas; Mass Spectrometry; Methods; Methylation; Theobromine; Theophylline; Uric Acid; Xanthines | 1972 |
[Reaction of purine derivatives with iodine used as a detection reagent. IX].
Topics: Caffeine; Indicators and Reagents; Iodine; Mercaptopurine; Methods; Purines; Spectrophotometry, Infrared; Theobromine; Theophylline | 1972 |
Inhibition of streptolysin O-induced haemolysis by theobromine sodium salicylate.
Topics: Animals; Caffeine; Erythrocytes; Hemolysis; In Vitro Techniques; Rabbits; Salicylates; Streptolysins; Theobromine; Theophylline | 1972 |
[Determination of the N-methyl group in organic substances on the micro and decimomilligram scale].
Topics: Acetanilides; Aminopyrine; Antipyrine; Caffeine; Diphenhydramine; Ephedrine; Indicators and Reagents; Methylation; Microchemistry; Theobromine; Theophylline | 1973 |
Urinary excretion of 3 -methylxanthine and related compounds in children.
Topics: Adolescent; Adult; Cacao; Caffeine; Child; Child, Preschool; Chromatography, Ion Exchange; Chromatography, Paper; Coffee; Diet; Humans; Infant; Intellectual Disability; Mass Spectrometry; Methylation; Neuromuscular Diseases; Spectrophotometry, Ultraviolet; Stereoisomerism; Tea; Theobromine; Theophylline; Xanthines | 1973 |
Activity of some isatin-beta-thiosemicarbazone and hydrazine dimethylxanthine derivatives against vaccinia virus in chick cells by agar diffusion method.
Topics: Agar; Animals; Antiviral Agents; Chick Embryo; Culture Techniques; Diffusion; Fibroblasts; Hydrazones; Indoles; Methods; Piperazines; Theobromine; Theophylline; Thiosemicarbazones; Vaccinia virus; Viral Plaque Assay | 1973 |
Determination of theophylline and probenecid in biological material.
Topics: Animals; Brain Chemistry; Caffeine; Chloroform; Chromatography; Chromatography, Gas; Hydrogen-Ion Concentration; Methods; Probenecid; Solvents; Theobromine; Theophylline; Water | 1974 |
GLC determination of theophylline in biological fluids.
Topics: Barbiturates; Chromatography, Gas; Indicators and Reagents; Methods; Quaternary Ammonium Compounds; Saliva; Solvents; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Uric Acid; Xanthines | 1974 |
The use of modified cellulose papers in routine toxicological analysis. 3. Xanthine CNS stimulants and antipyretics.
Topics: Analgesics; Caffeine; Cellulose; Central Nervous System; Chromatography, Paper; Paper; Theobromine; Theophylline; Xanthines | 1974 |
Effect of caffeine on adenylosuccinate lyase synthesis in Bacillus subtilis.
Topics: Bacillus subtilis; Caffeine; Culture Media; Dactinomycin; Lyases; Nucleosides; Nucleotides; Oxidoreductases; Puromycin; Succinates; Theobromine; Theophylline; Time Factors; Transferases; Xanthines | 1969 |
[Experimental studies of the influence of xanthine derivatives on cerebral metabolism].
Topics: Animals; Blood-Brain Barrier; Brain; Electroencephalography; Glucose; Hypoxia, Brain; Oxygen; Rats; Theobromine; Theophylline; Xanthines | 1972 |
Effect of theobromine, theophylline and caffeine on the mitosis of human lymphocytes.
Topics: Caffeine; Cells, Cultured; Colchicine; Female; Humans; Lectins; Lymphocytes; Male; Methods; Mitosis; Sex Factors; Theobromine; Theophylline | 1972 |
Complexation of acetaminophen with methyl xanthines.
Topics: Acetaminophen; Caffeine; Calorimetry; Chemistry, Pharmaceutical; Kinetics; Magnetic Resonance Spectroscopy; Solubility; Spectrophotometry; Spectrum Analysis; Theobromine; Theophylline | 1972 |
Caffeine metabolism by Penicillium roqueforti.
Topics: Caffeine; Carbon Isotopes; Chromatography, Thin Layer; Dealkylation; Penicillium; Theobromine; Theophylline | 1971 |
[Case of theophedrine poisoning].
Topics: Adolescent; Brain; Humans; Male; Movement Disorders; Theobromine; Theophylline | 1971 |
[Synthesis and properties of some Mannich bases of theophylline, 8-bromotheophylline and theobromine].
Topics: Chemical Phenomena; Chemistry; Theobromine; Theophylline | 1965 |
[Synthesis and nuclear resonance spectroscopic study of some theobromine- and theophylline- derivatives].
Topics: Magnetic Resonance Spectroscopy; Spectrum Analysis; Theobromine; Theophylline | 1969 |
[Solubilization of purines].
Topics: Caffeine; Polyvinyls; Purines; Solubility; Theobromine; Theophylline | 1969 |
Teratogenic actions of some methylated xanthines in mice.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Female; Fetus; Injections, Intraperitoneal; Male; Mice; Pregnancy; Teratoma; Theobromine; Theophylline | 1969 |
[Synthesis of substituted bis-xanthines].
Topics: Amines; Chemistry, Pharmaceutical; Ethers, Cyclic; Methylation; Theobromine; Theophylline; Xanthines | 1969 |
Detection of theophylline and theobromine by reactions with mercury (II) cyanide.
Topics: Caffeine; Chemical Phenomena; Chemistry; Cyanides; Mercury; Theobromine; Theophylline; Xanthines | 1970 |
[Pharmacologic properties of hydrazine derivatives of methylxanthines].
Topics: Animals; Cardiovascular System; Cats; Central Nervous System; Diuresis; Guinea Pigs; Hydrazines; Muscle, Smooth; Rabbits; Rats; Theobromine; Theophylline | 1970 |
[Factors influencing behaviour in thin-layer chromatography. 2. Thin-layer chromatography of caffeine, theophylline and theobromine on pH gradient layers].
Topics: Caffeine; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Theobromine; Theophylline | 1970 |
[Factors influencing behavior in thin-layer chromatography. I. The influence of the pH value in thin-layer chromatography of caffeine theophylline and theobromine on uniform layers].
Topics: Acids; Ammonia; Caffeine; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Theobromine; Theophylline | 1970 |
[Interaction between xanthines and noradrenaline- 3 H in the isolated rat heart].
Topics: Animals; Caffeine; Cardiac Output; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Myocardium; Norepinephrine; Perfusion; Rats; Theobromine; Theophylline; Tritium | 1970 |
[Titrations in concentrated saline medium: application to the argentimetric determination of theophylline and theobromine].
Topics: Potentiometry; Silver; Theobromine; Theophylline | 1971 |
[On the occurrence of theophylline in coffee].
Topics: Caffeine; Chromatography, Thin Layer; Coffee; Theobromine; Theophylline | 1967 |
[Studies on caffeine from synthesis and biosynthesis].
Topics: Caffeine; Chromatography; Chromatography, Thin Layer; Methods; Pharmacopoeias as Topic; Plants, Medicinal; Theobromine; Theophylline | 1967 |
Permeation of purine derivatives into the cerebrospinal fluid of dogs.
Topics: Amphetamine; Animals; Benzoates; Blood-Brain Barrier; Caffeine; Dogs; Ethylenediamines; Theobromine; Theophylline | 1968 |
The effect of caffeine on drug metabolism.
Topics: Acetanilides; Aminopyrine; Animals; Caffeine; Enzyme Induction; Ethionine; Liver; Microsomes; Nitrobenzenes; Puromycin; Rats; Theobromine; Theophylline | 1968 |
[On the theobromine and theophylline content of raw coffee and tea].
Topics: Chromatography, Thin Layer; Coffee; Methods; Spectrum Analysis; Tea; Theobromine; Theophylline | 1968 |
[Diuretic effect of purine derivatives based on the perfusion of the isolated kidney of dogs].
Topics: Animals; Caffeine; Diuretics; Dogs; Glomerular Filtration Rate; Kidney; Oxygen Consumption; Perfusion; Potassium; Sodium; Theobromine; Theophylline; Time Factors; Vascular Resistance | 1968 |
Determination of caffeine in serum and urine.
Topics: Benzene; Caffeine; Indicators and Reagents; Methods; Spectrum Analysis; Theobromine; Theophylline | 1969 |
Solubility profiles for the xanthines in dioxane--water mixtures.
Topics: Caffeine; Dioxins; Solubility; Spectrophotometry; Theobromine; Theophylline | 1965 |
[A new method for thin-layer chromatographic separation of caffeine, theobromin and theophylline].
Topics: Caffeine; Chromatography, Thin Layer; In Vitro Techniques; Theobromine; Theophylline | 1965 |
[Quantitative determination of hydroxyethyltheophylline and hydroxypropyltheobromine with the aid of their polyiodides].
Topics: Chemistry Techniques, Analytical; Iodides; Theobromine; Theophylline | 1965 |
[Study of solvent effect on nuclear magnetic resonance. I. Caffeine and its derivatives].
Topics: Caffeine; Hydrocarbons, Halogenated; Magnetic Resonance Spectroscopy; Solvents; Theobromine; Theophylline | 1965 |
[Thin-layer chromatographic separation of some purine derivatives, including uric acid].
Topics: Adenine; Caffeine; Chromatography, Thin Layer; Guanine; Hypoxanthines; Purines; Theobromine; Theophylline; Uric Acid; Xanthines | 1966 |
New drugs in xanthine derivatives XXVI. Pyridylthioethyl derivatives of theobromine and theophylline, and products of their oxidation.
Topics: Chemistry, Organic; Organic Chemistry Phenomena; Oxidation-Reduction; Pyridines; Sulfones; Sulfoxides; Theobromine; Theophylline; Xanthines | 1966 |
[Detection of caffeine, theophylline, theobromine and some of their derivatives by thin layer chromatography].
Topics: Blood Chemical Analysis; Caffeine; Chromatography, Thin Layer; Humans; Indicators and Reagents; Male; Solvents; Theobromine; Theophylline; Urine | 1966 |
[Gas chromatographic separation of various xanthine derivatives].
Topics: Caffeine; Chromatography, Gas; Theobromine; Theophylline; Xanthines | 1966 |
[Determination of Theobromine and its metabolites in urine].
Topics: Caffeine; Chromatography, Paper; Food Contamination; Humans; Spectrophotometry; Theobromine; Theophylline; Xanthines | 1966 |
Effect of functional group substituents on the paper chromatography of purines and pyrimidines.
Topics: Adenine; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; Guanine; Hydrogen-Ion Concentration; Nitriles; Purines; Pyrimidines; Theobromine; Theophylline; Thymine; Uracil; Water; Xanthines | 1967 |
Electrical conductivity of a docusate sodium coacervate system.
Topics: Caffeine; Chemical Phenomena; Chemistry, Physical; Cytoplasm; Dioctyl Sulfosuccinic Acid; Electric Conductivity; Glucose; Glucosephosphates; Humans; Models, Biological; Succinates; Sucrose; Theobromine; Theophylline | 1984 |
Central nervous system pharmacology of the dietary methylxanthines.
Topics: Acetylcholine; Adolescent; Adult; Aged; Body Weight; Caffeine; Central Nervous System; Diet; Dopamine; Dose-Response Relationship, Drug; Feeding Behavior; Female; Humans; Lethal Dose 50; Male; Middle Aged; Motor Activity; Norepinephrine; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Serotonin; Sleep; Substance-Related Disorders; Theobromine; Theophylline | 1984 |
Antimalarial activity of inhibitors of ADP-ribosyl transferase against Plasmodium yoelii infection in mice. 1. Preliminary data.
Topics: Animals; Antimalarials; Benzamides; Chloroquine; Drug Evaluation, Preclinical; Malaria; Male; Mice; Niacinamide; Nucleotidyltransferases; Plasmodium; Poly(ADP-ribose) Polymerases; Theobromine; Theophylline | 1982 |
Character and meaning of quasi-morphine withdrawal phenomena elicited by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Humans; Hypoxanthines; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Phosphodiesterase Inhibitors; Pyrimidines; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Triazoles; Xanthines | 1981 |
A tentative explanation of the stimulatory effect of methylxanthines (pentoxifylline and isobutylmethylxanthine) on the secretory process in rat extraorbital lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Lacrimal Apparatus; Male; Norepinephrine; Pentoxifylline; Proteins; Rats; Rats, Inbred Strains; Sympathomimetics; Theobromine; Theophylline; Xanthines | 1981 |
Characterization of basal and methylxanthine-stimulated Ca2+ transport in abalone spermatozoa.
Topics: 1-Methyl-3-isobutylxanthine; Aminophylline; Animals; Biological Transport, Active; Caffeine; Calcium; Hydrogen-Ion Concentration; Kinetics; Male; Mollusca; Potassium Cyanide; Spermatozoa; Theobromine; Theophylline; Xanthines | 1984 |
Effects of pentoxifylline and various methylxanthine derivatives on transepithelial water permeability of frog urinary bladder.
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Epithelium; Osmosis; Pentoxifylline; Permeability; Rana esculenta; Theobromine; Theophylline; Urinary Bladder; Vasopressins; Water; Xanthines | 1981 |
Modification of radiation-induced division delay by caffeine analogues and dibutyryl cyclic AMP.
Topics: Animals; Bucladesine; Caffeine; Cell Division; Cells, Cultured; Cricetinae; Cricetulus; Female; Ovary; Theobromine; Theophylline; X-Rays | 1982 |
Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Brain; Caffeine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theobromine; Theophylline; Xanthines | 1983 |
Inhibition of soluble 5'-nucleotidase from rat brain by different xanthine derivatives.
Topics: 5'-Nucleotidase; Animals; Brain; Kinetics; Male; Nucleotidases; Rats; Rats, Inbred Strains; Solubility; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines | 1983 |
Inhibition of gamma-ray dose-rate effects by D2O and inhibitors of poly(ADP-ribose) synthetase in cultured mammalian L5178Y cells.
Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Cobalt Radioisotopes; Deuterium; Deuterium Oxide; Dose-Response Relationship, Radiation; Gamma Rays; Leukemia L5178; Leukemia, Experimental; Mice; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerase Inhibitors; Theobromine; Theophylline; Water | 1984 |
Effect of colchicine & methylated purines on UV-induced mitotic gene conversion in Saccharomyces cerevisiae.
Topics: Caffeine; Colchicine; Gene Conversion; Genes, Fungal; Mitosis; Saccharomyces cerevisiae; Theobromine; Theophylline; Ultraviolet Rays | 1983 |
Potentiating effects of methylxanthines on teratogenicity of mitomycin C in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Caffeine; Drug Synergism; Female; Mice; Mice, Inbred ICR; Mitomycin; Mitomycins; Pregnancy; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines | 1983 |
Caffeine and its dimethylxanthines and fetal cerebral development in rat.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Caffeine; Female; Fetus; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1984 |
[Effect of theophylline and theobromine on cell respiration and calcium transport in isolated rat liver mitochondria].
Topics: Animals; Biological Transport, Active; Caffeine; Calcium; Female; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1984 |
Caffeine, theophylline and theobromine in pregnancy.
Topics: Caffeine; Female; Humans; Pregnancy; Theobromine; Theophylline | 1984 |
Tea: the plant and its manufacture; chemistry and consumption of the beverage.
Topics: Beverages; Caffeine; Drinking; Flavanones; Flavins; Flavonoids; Food Handling; Humans; Tea; Theobromine; Theophylline | 1984 |
Influence of some common methylxanthines on contractile responses and calcium mobilization of ileal, vas deferens and bladder smooth muscle.
Topics: Animals; Caffeine; Calcium; Ileum; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Urinary Bladder; Vas Deferens; Xanthines | 1983 |
Determination of caffeine, theophylline and theobromine in serum and saliva using high-performance liquid chromatography.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Saliva; Theobromine; Theophylline | 1984 |
Simultaneous determination of caffeine and its N-demethylated metabolites in umbilical cord plasma using high-performance liquid chromatography.
Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Dealkylation; Female; Fetal Blood; Humans; Infant; Theobromine; Theophylline | 1984 |
High-performance liquid chromatographic determination of theobromine, theophylline and caffeine in food products.
Topics: Beverages; Cacao; Caffeine; Candy; Chromatography, High Pressure Liquid; Coffee; Hydrogen-Ion Concentration; Theobromine; Theophylline | 1984 |
Comparative inhibiting effects of methylxanthines on urethan-induced tumors, malformations, and presumed somatic mutations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Caffeine; DNA Repair; Lung Neoplasms; Mice; Mice, Inbred ICR; Theobromine; Theophylline; Urethane; Xanthines | 1983 |
Theobromine metabolism and pharmacokinetics in pregnant and nonpregnant Sprague-Dawley rats.
Topics: Animals; Female; Kinetics; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1983 |
Disposition of caffeine and its metabolites in man.
Topics: Adult; Biotransformation; Caffeine; Female; Humans; Kinetics; Male; Theobromine; Theophylline | 1983 |
[Therapeutic efficacy of pentoxifylline in peripheral artery diseases: its clinical value].
Topics: Aged; Arterial Occlusive Diseases; Blood Viscosity; Female; Humans; Male; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate | 1983 |
Inhibitory effects of methylxanthines on the activity of xanthine oxidase.
Topics: Animals; Brain; Buffaloes; Caffeine; Female; In Vitro Techniques; Kidney; Kinetics; Lung; Milk; Myocardium; Rats; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase; Xanthines | 1980 |
Regulation of human drug metabolism by dietary factors.
Topics: Adult; Antipyrine; Biotransformation; Caffeine; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Half-Life; Humans; Metabolic Clearance Rate; Oxidation-Reduction; Pharmaceutical Preparations; Theobromine; Theophylline; Vegetables | 1980 |
Deuteromethylation of dimethylxanthines: a gas chromatographic mass spectrometric method for confirmatory analysis in horse urine extracts.
Topics: Animals; Doping in Sports; Gas Chromatography-Mass Spectrometry; Horses; Theobromine; Theophylline | 1982 |
Effects of caffeine, theophylline and theobromine on scheduled controlled responding in rats.
Topics: Animals; Behavior, Animal; Caffeine; Conditioning, Operant; Male; Rats; Rats, Inbred Strains; Reinforcement Schedule; Theobromine; Theophylline; Xanthines | 1982 |
Effects of methylxanthines on superprecipitation of myosin B extracted from rabbit fast skeletal muscle.
Topics: Animals; Caffeine; Chemical Precipitation; Muscle Proteins; Muscles; Myosins; Rabbits; Solubility; Theobromine; Theophylline; Xanthines | 1982 |
Sister chromatid exchanges induced by methylxanthines contained in coffee, tea and cocoa.
Topics: Animals; Bone Marrow; Caffeine; Coca; Coffee; Cricetinae; Cricetulus; Crossing Over, Genetic; Plants, Medicinal; Sister Chromatid Exchange; Tea; Theobromine; Theophylline; Xanthines | 1982 |
Reversed-phase liquid chromatographic investigation of UV-absorbing low-molecular-weight compounds in saliva.
Topics: Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Humans; Molecular Weight; Saliva; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Time Factors | 1982 |
Urinary excretion of an uracilic metabolite from caffeine by rat, monkey and man.
Topics: Adult; Animals; Biotransformation; Caffeine; Humans; Macaca fascicularis; Male; Rats; Species Specificity; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1981 |
[Effect of methylxanthines on urinary prostaglandin E excretion of rats acutely loaded with salt and water (author's transl)].
Topics: Animals; Caffeine; Diuresis; Electrolytes; Isotonic Solutions; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium Chloride; Theobromine; Theophylline; Water | 1981 |
Extended Hildebrand Solubility Approach: methylxanthines in mixed solvents.
Topics: Caffeine; Chemical Phenomena; Chemistry, Physical; Dioxanes; Solubility; Solvents; Theobromine; Theophylline; Water; Xanthines | 1981 |
Excretion of methylxanthines in human milk.
Topics: Adult; Beverages; Caffeine; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Infant; Infant, Newborn; Kinetics; Lactation; Milk, Human; Pregnancy; Saliva; Theobromine; Theophylline | 1981 |
Effects of methylxanthines on urinary prostaglandin E excretion in rats.
Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Electrolytes; Indomethacin; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1981 |
Reversed-phase high-performance liquid chromatographic determination of caffeine and its N-demethylated metabolites in dog plasma.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Dogs; Male; Reference Values; Theobromine; Theophylline; Time Factors | 1981 |
A study of caffeine in tea.
Topics: Caffeine; Methods; Tea; Theobromine; Theophylline | 1980 |
Relationship between the clearance of caffeine and its 7-N-demethylation in developing beagle puppies.
Topics: Aging; Animals; Caffeine; Dealkylation; Dogs; Female; Kinetics; Theobromine; Theophylline; Xanthines | 1980 |
The simultaneous determination of theophylline, theobromine and caffeine in plasma by high performance liquid chromatography.
Topics: Adult; Caffeine; Child; Chromatography, High Pressure Liquid; Humans; Theobromine; Theophylline | 1980 |
Simultaneous determination of dyphylline and theophylline in human plasma by high-performance liquid chromatography.
Topics: Asthma; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Humans; Reference Values; Theobromine; Theophylline | 1980 |
Characterization of the methylxanthine-induced propagated wave phenomenon in striated muscle.
Topics: Animals; Caffeine; Chick Embryo; Halothane; Histocytochemistry; Muscle Contraction; Muscles; Quinine; Theobromine; Theophylline | 1980 |
The effect of TPP, theophylline and theobromine on the angiogenic activity of mononuclear leucocytes obtained from diabetic patients with proliferative retinopathy.
Topics: Adolescent; Adult; Amino Acids; Animals; Carbohydrates; Child; Diabetic Retinopathy; Drug Combinations; Humans; Humic Substances; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Soil; Theobromine; Theophylline; Uronic Acids | 1993 |
Effects of methylxanthine derivatives on adriamycin concentration and antitumor activity.
Topics: Animals; Caffeine; Carcinoma, Ehrlich Tumor; Doxorubicin; Drug Synergism; Male; Mice; Pentoxifylline; Theobromine; Theophylline | 1995 |
Highly sensitive and rapid determination of theophylline, theobromine and caffeine in human plasma and urine by gradient capillary high-performance liquid chromatography-frit-fast atom bombardment mass spectrometry.
Topics: Caffeine; Capillary Action; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Fast Atom Bombardment; Theobromine; Theophylline | 1995 |
Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats.
Topics: Administration, Oral; Animals; Biological Assay; Body Weight; Caffeine; Coffee; Diethylnitrosamine; Glutathione Transferase; Glyoxal; Liver; Liver Neoplasms; Male; Organ Size; Pyruvaldehyde; Rats; Rats, Inbred F344; Theobromine; Theophylline | 1995 |
Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells.
Topics: 2-Aminopurine; Animals; Apoptosis; Caffeine; DNA Damage; Dose-Response Relationship, Radiation; G2 Phase; Kinetics; Linear Energy Transfer; Lymphoma, T-Cell; Mice; Mitosis; Theobromine; Theophylline; Tumor Cells, Cultured | 1995 |
Determination of xanthines by high-performance liquid chromatography and thin-layer chromatography in horse urine after ingestion of Guaraná powder.
Topics: Administration, Oral; Animals; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Combinations; Horses; Regression Analysis; Reproducibility of Results; Seeds; Theobromine; Theophylline; Xanthines | 1994 |
Effects of caffeine and related methylxanthines on fetal mouse palates cultured in vitro.
Topics: Animals; Caffeine; Chi-Square Distribution; Female; Male; Mice; Mice, Inbred ICR; Organ Culture Techniques; Palate; Theobromine; Theophylline; Xanthines | 1994 |
Microdialysis sampling coupled on-line to fast microbore liquid chromatography.
Topics: Acetaminophen; Animals; Caffeine; Chromatography, High Pressure Liquid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Theobromine; Theophylline | 1995 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; Electric Stimulation; Extracellular Space; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serum Albumin, Bovine; Theobromine; Theophylline; Verapamil; Xanthines | 1993 |
[Development of the method for analysis of theophylline and its related compounds using capillary high-performance liquid chromatography/fast atom bombardment-mass spectrometry].
Topics: Caffeine; Chromatography, High Pressure Liquid; Hair; Humans; Spectrometry, Mass, Fast Atom Bombardment; Theobromine; Theophylline | 1994 |
Comparison of the effects of caffeine and other methylxanthines on [Ca2+]i in rat ventricular myocytes.
Topics: Animals; Caffeine; Calcium; Cell Membrane Permeability; Chemical Phenomena; Chemistry, Physical; Fluorescent Dyes; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Myocardium; Rats; Solubility; Theobromine; Theophylline; Xanthines | 1994 |
Modulation of striatal adenosine A1 and A2 receptors induces rotational behaviour in response to dopaminergic stimulation in intact rats.
Topics: Adenosine; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dopamine; Injections, Intraperitoneal; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1994 |
Metabolism of caffeine and theophylline in rats with malaria and endotoxin-induced fever.
Topics: Administration, Oral; Animals; Caffeine; Endotoxins; Fever; Injections, Intravenous; Malaria; Male; Metabolic Clearance Rate; Plasmodium berghei; Rats; Rats, Wistar; Theobromine; Theophylline | 1993 |
Adenosine receptor antagonists potentiate dopamine receptor agonist-induced rotational behavior in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Bromocriptine; Male; Motor Activity; Oxidopamine; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Theobromine; Theophylline; Time Factors; Xanthines | 1993 |
Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms.
Topics: Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Oxidoreductases; Theobromine; Theophylline; Uric Acid | 1994 |
Accumulation of theophylline, theobromine and paraxanthine in the fetal rat brain following a single oral dose of caffeine.
Topics: Animals; Biotransformation; Brain; Caffeine; Chromatography, High Pressure Liquid; Female; Pregnancy; Rats; Rats, Wistar; Theobromine; Theophylline; Xanthines | 1993 |
Attenuation of potassium cyanide-mediated neuronal cell death by adenosine.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Neurons; Osmolar Concentration; Potassium Cyanide; Purinergic Antagonists; Theobromine; Theophylline | 1993 |
[Determination of six main components in compound theophylline tablet by convolution curve method after prior separation by column partition chromatography].
Topics: Aminopyrine; Chromatography; Drug Combinations; Quality Control; Tablets; Theobromine; Theophylline | 1993 |
Enhancement of the behavioral toxicity induced by combined administration of ethanol with methylxanthines: evaluation by discrete avoidance in mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Caffeine; Drug Synergism; Ethanol; Male; Mice; Mice, Inbred Strains; Theobromine; Theophylline; Xanthines | 1993 |
Modulation of vasopressin actions on human platelets by plasma adenosine and theophylline: gender differences.
Topics: Adenosine; Adult; Arginine Vasopressin; Blood Platelets; Female; Humans; Male; Middle Aged; Platelet Aggregation; Serotonin; Sex Characteristics; Theobromine; Theophylline | 1993 |
Comparison of hepatic drug-oxidizing activity after simultaneous administration of two probe drugs, caffeine and trimethadione, to human subjects.
Topics: Adult; Caffeine; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Half-Life; Humans; Liver; Male; Middle Aged; Oxidation-Reduction; Oxygenases; Theobromine; Theophylline; Trimethadione | 1993 |
Excretion of caffeine and its primary degradation products into bile.
Topics: Adult; Aged; Bile; Bilirubin; Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Theobromine; Theophylline; Time Factors | 1993 |
Vasodilatation produced by adenosine in isolated rat perfused mesenteric artery: a role for endothelium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Glyburide; Male; Mesenteric Arteries; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Suramin; Theobromine; Theophylline; Vasodilation; Vasodilator Agents | 1995 |
Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway.
Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Caffeine; Dopamine Agonists; Ergolines; Genes, fos; Globus Pallidus; Immunohistochemistry; Male; Neostriatum; Neural Pathways; Phosphodiesterase Inhibitors; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine; Theobromine; Theophylline | 1995 |
The role of adenosine in the hypotensive actions of morphine.
Topics: Adenosine; Animals; Blood Pressure; Female; Guanethidine; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1995 |
Purine suppression of proliferation of Sertoli-like TM4 cells in culture.
Topics: Adenosine; Animals; Caffeine; Cell Division; Cells, Cultured; Male; Mice; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1; Sertoli Cells; Theobromine; Theophylline | 1995 |
Pharmacokinetics of caffeine in the oestrogen-implanted ovariectomized ewe.
Topics: Animals; Area Under Curve; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Implants; Estradiol; Estrus Synchronization; Female; Half-Life; Injections, Intravenous; Ovariectomy; Sheep; Theobromine; Theophylline | 1996 |
Assessment of dimethylxanthine formation from caffeine in healthy adults: comparison between plasma and saliva concentrations and urinary excretion of metabolites.
Topics: Adult; Caffeine; Female; Humans; Male; Saliva; Theobromine; Theophylline | 1996 |
Role of adenosine receptor subtypes in neural stunning of sympathetic coronary innervation.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Male; Myocardial Stunning; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sympathetic Nervous System; Theobromine; Theophylline; Vasoconstriction; Xanthines | 1997 |
Isotopic effects on retention times of caffeine and its metabolites 1,3,7-trimethyluric acid, theophylline, theobromine and paraxanthine.
Topics: Animals; Caffeine; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Kidney; Male; Rats; Rats, Wistar; Theobromine; Theophylline; Uric Acid | 1997 |
Determination of caffeine and its metabolites by micellar electrokinetic capillary electrophoresis.
Topics: Animals; Beverages; Buffers; Caffeine; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Rats; Sodium Dodecyl Sulfate; Tablets; Theobromine; Theophylline; Uric Acid | 1997 |
[Development of syringe-type off line pre-column and simultaneous quantitation of four xanthine derivatives (caffeine, theobromine, theophylline and paraxanthine) in serum].
Topics: Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Humans; Theobromine; Theophylline; Xanthines | 1997 |
Inhibitory effect of methylxanthines on glycine-induced Cl current in dissociated rat hippocampal neurons.
Topics: Animals; Caffeine; Chloride Channels; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Pentoxifylline; Pyramidal Cells; Rats; Rats, Wistar; Theobromine; Theophylline; Xanthines | 1993 |
A role for adenosine A2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adenosine; Animals; Hippocampus; Long-Term Potentiation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1997 |
Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes.
Topics: Animals; Biotransformation; Caffeine; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Methimazole; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Proadifen; Rats; Rats, Sprague-Dawley; Species Specificity; Theobromine; Theophylline | 1997 |
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antagonists; Haloperidol; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Scopolamine; Theobromine; Theophylline; Xanthines | 1997 |
Convulsant effects of some xanthine derivatives in genetically epilepsy-prone rats.
Topics: 1-Methyl-3-isobutylxanthine; Acoustic Stimulation; Animals; Caffeine; Convulsants; Dyphylline; Electroencephalography; Epilepsy; Female; Lipid Metabolism; Male; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines | 1997 |
Comparative pharmacokinetics of caffeine and three metabolites in clinically normal horses and donkeys.
Topics: Animals; Caffeine; Equidae; Female; Horses; Male; Metabolic Clearance Rate; Species Specificity; Theobromine; Theophylline; Time Factors | 1997 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Enzyme Inhibitors; Hippocampus; Neurons; Neurotoxins; Nitric Oxide; Organ Culture Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1997 |
Theophylline metabolism in higher plants.
Topics: Plants; Tea; Theobromine; Theophylline | 1997 |
Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine.
Topics: Animals; Behavior, Animal; Body Temperature; Edema; Histamine Release; Injections, Subcutaneous; Male; Pain; Plethysmography; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline | 1997 |
Sensitization of Burkholderia cepacia to antibiotics by cationic drugs.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Azithromycin; Burkholderia cepacia; Cations; Ceftazidime; Dibucaine; Diphenhydramine; Drug Therapy, Combination; Famotidine; Gentamicins; Lidocaine; Microbial Sensitivity Tests; Structure-Activity Relationship; Theobromine; Theophylline | 1998 |
Evaluation of the toxicity of guarana with in vitro bioassays.
Topics: Animals; Caffeine; Cell Division; CHO Cells; Cricetinae; Drug Combinations; Indicators and Reagents; Neutral Red; Organic Chemicals; Photobacterium; Plant Extracts; Proteins; Seeds; Tetrazolium Salts; Theobromine; Theophylline | 1998 |
Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation.
Topics: Animals; Caffeine; Cell Adhesion; Cell Division; Collagen; Laminin; Lung Neoplasms; Male; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Neoplasm Invasiveness; Theobromine; Theophylline; Transglutaminases; Tumor Cells, Cultured | 1998 |
CPT (8-cyclopentyl theophylline) corrects CFTR antibody inhibited mucin secretion.
Topics: Adrenergic beta-Agonists; Animals; Antibodies; Cells, Cultured; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Isoproterenol; Mucins; Purinergic P1 Receptor Antagonists; Rats; Submandibular Gland; Theobromine; Theophylline | 1998 |
Effect of guarana on exercise in normal and epinephrine-induced glycogenolytic mice.
Topics: Animals; Blood Glucose; Caffeine; Drug Combinations; Epinephrine; Fasting; Glycogen; Male; Maltose; Mice; Physical Conditioning, Animal; Seeds; Theobromine; Theophylline | 1998 |
Actions of adenosine A1 and A2 receptor antagonists on CFTR antibody-inhibited beta-adrenergic mucin secretion response.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies; Chromatography, Gel; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electrophoresis, Cellulose Acetate; Mucins; Phosphorylation; Precipitin Tests; Purinergic P1 Receptor Antagonists; Rats; Receptors, Adrenergic, beta; Submandibular Gland; Theobromine; Theophylline | 1998 |
Pharmacological interactions between magnesium ion and adenosine on monoaminergic system in the central nervous system.
Topics: Adenosine; Animals; Biogenic Monoamines; Caffeine; Carbamazepine; Central Nervous System; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Magnesium; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline; Visual Cortex | 1998 |
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents | 1999 |
Effect of toluidines and dinitrotoluenes on caffeine metabolic ratio in rat.
Topics: Animals; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Dealkylation; Dinitrobenzenes; Male; Rats; Rats, Wistar; Theobromine; Theophylline; Toluidines | 1999 |
Interaction between purinoceptor subtypes on hippocampal serotonergic transmission using in vivo microdialysis.
Topics: Adenosine Triphosphate; Animals; Hippocampus; Male; Microdialysis; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Serotonin; Theobromine; Theophylline; Thionucleotides | 1999 |
Effects of adenosinergic agents on the vascular resistance and on the optic nerve response in the perfused cat eye.
Topics: Adenosine; Animals; Cats; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Female; Optic Nerve; Perfusion; Phenethylamines; Photic Stimulation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retina; Theobromine; Theophylline; Vascular Resistance | 1999 |
Contributions of adenosine receptor activation to the ocular actions of epinephrine.
Topics: Adenosine; Adrenergic Agonists; Animals; Aqueous Humor; Epinephrine; Inosine; Intraocular Pressure; Ophthalmic Solutions; Pupil; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Chronic effects of xanthines on levels of central receptors in mice.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain Chemistry; Caffeine; Calcium Channels; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Drug Interactions; Gene Expression Regulation; Male; Mice; Nerve Tissue Proteins; Pentoxifylline; Radioligand Assay; Receptors, Cholinergic; Receptors, Drug; Receptors, GABA; Receptors, Purinergic P1; Receptors, Serotonin; Theobromine; Theophylline; Xanthines | 1999 |
Mutagenic and genotoxic effects of theophylline and theobromine in Salmonella assay and in vivo sister chromatid exchanges in bone marrow cells of mice.
Topics: Animals; Bone Marrow Cells; Bronchodilator Agents; Humans; Male; Mice; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium; Sister Chromatid Exchange; Theobromine; Theophylline | 1999 |
Purification and partial characterization of caffeine oxidase--A novel enzyme from a mixed culture consortium.
Topics: Caffeine; Klebsiella; Oxidation-Reduction; Oxygenases; Rhodococcus; Substrate Specificity; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase | 1999 |
Separation of theophylline, caffeine and related drugs by normal-phase capillary electrochromatography.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Electric Conductivity; Electrophoresis, Capillary; Hydrochlorothiazide; Molecular Structure; Niacin; Phenylbutazone; Theobromine; Theophylline | 1999 |
An adenosine A3 receptor-selective agonist does not modulate calcium-activated potassium currents in hippocampal CA1 pyramidal neurons.
Topics: Adenosine; Animals; Calcium; Hippocampus; In Vitro Techniques; Male; Potassium Channels; Purinergic P1 Receptor Agonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Extraction of purine alkaloids from maté (Ilex paraguariensis) using supercritical CO(2).
Topics: Beverages; Caffeine; Carbon Dioxide; Chromatography, High Pressure Liquid; Magnoliopsida; Pressure; Solubility; Theobromine; Theophylline | 1999 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2000 |
Differential activities of CYP1A isozymes in hepatic and intestinal microsomes of control and 3-methylcholanthrene-induced rats.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Induction; Enzyme Inhibitors; Injections, Intraperitoneal; Intestine, Small; Ketoconazole; Liver; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Wistar; Theobromine; Theophylline | 2000 |
The pharmacokinetics, metabolism and urinary detection time of caffeine in camels.
Topics: Animals; Area Under Curve; Caffeine; Camelus; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Injections, Intravenous; Male; Protein Binding; Regression Analysis; Statistics, Nonparametric; Theobromine; Theophylline | 2000 |
Myoglobinuria after ingestion of extracts of guarana, Ginkgo biloba and kava.
Topics: Adult; Caffeine; Drug Combinations; Ginkgo biloba; Humans; Kava; Male; Myoglobinuria; Plant Extracts; Plants, Medicinal; Theobromine; Theophylline | 2000 |
Paraxanthine, a caffeine metabolite, dose dependently increases [Ca(2+)](i) in skeletal muscle.
Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Hindlimb; In Vitro Techniques; Intracellular Membranes; Male; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Osmolar Concentration; Procaine; Theobromine; Theophylline | 2000 |
Mediation of the cardiovascular response to spinal gamma-aminobutyric acid(B) receptor stimulation by adenosine A(1) receptors in anesthetized rats.
Topics: Adenosine; Amino Acids, Neutral; Animals; Baclofen; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Spinal Cord; Sympathetic Nervous System; Theobromine; Theophylline | 2000 |
Suspected caffeine and ephedrine toxicosis resulting from ingestion of an herbal supplement containing guarana and ma huang in dogs: 47 cases (1997-1999).
Topics: Animals; Caffeine; Central Nervous System Stimulants; Dietary Supplements; Dog Diseases; Dogs; Drug Combinations; Ephedrine; Female; Male; Phytotherapy; Retrospective Studies; Theobromine; Theophylline | 2001 |
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase | 2001 |
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.
Topics: Adenosine; Animals; Caffeine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Theophylline; Transfection | 2001 |
[Cerebral infarction in a patient consuming MaHuang extract and guarana].
Topics: Adult; Caffeine; Cerebral Angiography; Cerebral Infarction; Drug Combinations; Ephedrine; Female; Humans; Theobromine; Theophylline | 2001 |
Seizure activity and unresponsiveness after hydroxycut ingestion.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Citrates; Drug Combinations; Drugs, Chinese Herbal; Ephedra sinica; Ephedrine; Humans; Male; Phytotherapy; Picolinic Acids; Plant Preparations; Polysaccharides; Seizures; Theobromine; Theophylline | 2001 |
Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products.
Topics: Adult; Beverages; Caffeine; Drug Combinations; Fatal Outcome; Female; Food, Organic; Humans; Mitral Valve Prolapse; Theobromine; Theophylline; Ventricular Fibrillation | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
Nanoparticles in plant extracts--factors which influence the formation of nanoparticles in black tea infusions.
Topics: Absorptiometry, Photon; Caffeine; Microspheres; Models, Molecular; Particle Size; Plant Extracts; Tea; Theobromine; Theophylline | 2001 |
Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
Topics: Adenosine; Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Ischemia; Ischemic Preconditioning; Kidney; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery Obstruction; Renal Circulation; Reperfusion Injury; Theobromine; Theophylline; Time Factors; Ultrasonography, Doppler, Pulsed; Xanthines | 2001 |
Simultaneous determination of artificial sweeteners, preservatives, caffeine, theobromine and theophylline in food and pharmaceutical preparations by ion chromatography.
Topics: Caffeine; Chromatography, Liquid; Food Analysis; Food Preservatives; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet; Sweetening Agents; Theobromine; Theophylline | 2001 |
Platinum complexes of oxopurines: cis-bis(theophyllinato-N7)bis(triphenylphosphine)platinum(II) and cis-chloro(theobrominato-N1)bis(triphenylphosphine)platinum(II) ethanol hemisolvate.
Topics: Antineoplastic Agents; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Organoplatinum Compounds; Theobromine; Theophylline | 2002 |
Effects of caffeine and its reactive metabolites theophylline and theobromine on the differentiating testis.
Topics: Animals; Caffeine; Cell Differentiation; Female; Gestational Age; Leydig Cells; Male; Maternal-Fetal Exchange; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Seminiferous Tubules; Testis; Theobromine; Theophylline | 2001 |
Simultaneous determination of caffeine, theobromine, and theophylline by high-performance liquid chromatography.
Topics: Beverages; Caffeine; Calibration; Chromatography, High Pressure Liquid; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 2002 |
Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.
Topics: Adenosine; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium; Cells, Cultured; Dermis; DNA Primers; Endothelial Growth Factors; Gene Expression; Hair; Humans; Hypertrichosis; Lymphokines; Minoxidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Antagonists; Receptors, Drug; Receptors, Purinergic P1; Sulfonylurea Receptors; Theobromine; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2001 |
Study of catechin and xanthine tea profiles as geographical tracers.
Topics: Caffeine; Catechin; China; Chromatography, High Pressure Liquid; Gallic Acid; India; Japan; Kenya; Sri Lanka; Tea; Theobromine; Theophylline; Xanthines | 2002 |
Continuous measurement of caffeine and two metabolites in blood and skeletal muscle of unrestrained adult horses by semi-automated in vivo microdialysis.
Topics: Animals; Area Under Curve; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Female; Horses; Injections, Intravenous; Microdialysis; Muscle, Skeletal; Reproducibility of Results; Theobromine; Theophylline | 2001 |
Inhibition of vaccinia virus replication by adenosine in BSC-40 cells: involvement of A(2) receptor-mediated PKA activation.
Topics: Adenosine; Animals; Antiviral Agents; Carrier Proteins; Cell Line; Coculture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Intracellular Signaling Peptides and Proteins; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Theobromine; Theophylline; Vaccinia virus; Virus Replication | 2002 |
Electronic structure of some adenosine receptor antagonists. III. Quantitative investigation of the electronic absorption spectra of alkyl xanthines.
Topics: Caffeine; Purinergic P1 Receptor Antagonists; Spectrum Analysis; Theobromine; Theophylline | 2002 |
Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators.
Topics: Adenosine; Animals; Dipyridamole; Glucose; Islets of Langerhans; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Theobromine; Theophylline; Vagotomy; Vasodilator Agents; Xanthines | 2002 |
Caffeine potentiates the discriminative-stimulus effects of nicotine in rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Differential Threshold; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Ganglionic Stimulants; Generalization, Stimulus; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Theobromine; Theophylline; Vasodilator Agents | 2002 |
[Direct determination of purine bases in tea by reversed-phase high performance liquid chromatography].
Topics: Caffeine; Chromatography, High Pressure Liquid; Tea; Theobromine; Theophylline | 1999 |
Antagonism of adenosine receptors by caffeine and caffeine metabolites in equine forebrain tissues.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Horses; Male; Neostriatum; Prosencephalon; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Theophylline | 2003 |
Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine.
Topics: Animals; Biotransformation; Caffeine; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ellagic Acid; Enzyme Induction; Glutathione Transferase; Hydrolyzable Tannins; Hydroxybenzoates; Kidney; Liver; Male; Oxidoreductases; Rats; Rats, Wistar; Theobromine; Theophylline; Toluidines | 2003 |
De-intercalation of ethidium bromide and acridine orange by xanthine derivatives and their modulatory effect on anticancer agents: a study of DNA-directed toxicity enlightened by time correlated single photon counting.
Topics: Acridine Orange; Antineoplastic Agents; Caffeine; DNA; Ethidium; Fluorescent Dyes; Humans; Intercalating Agents; Models, Biological; Photons; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 2003 |
RNA binding efficacy of theophylline, theobromine and caffeine.
Topics: Animals; Caffeine; RNA, Fungal; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Theobromine; Theophylline | 2003 |
Study on the paper substrate room temperature phosphorescence of theobromine, caffeine and theophylline and analytical application.
Topics: Aminophylline; Cacao; Caffeine; Coffee; Hydrogen-Ion Concentration; Luminescence; Metals, Heavy; Paper; Spectrometry, Fluorescence; Tea; Temperature; Theobromine; Theophylline | 2003 |
Selective solid-phase extraction sorbent for caffeine made by molecular imprinting.
Topics: Beverages; Caffeine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Humans; Hydrogen-Ion Concentration; Polymers; Theobromine; Theophylline | 2002 |
The action of solubilizing agents on the solubility of xanthine derivatives in water. II. The application of conductimetric titrations to the study of xanthine combinations.
Topics: Caffeine; Diuretics; Solubility; Theobromine; Theophylline; Water; Xanthine; Xanthines | 1952 |
The action of solubilizing agents on the solubility of xanthine derivatives in water. III. The application of cryoscopy to the study of caffeine, theophylline, and theobromine with solubilizing agents.
Topics: Caffeine; Diuretics; Solubility; Theobromine; Theophylline; Water; Xanthines | 1952 |
Growth promotion in carnivorous protozoa by substituted purines.
Topics: Animals; Caffeine; Eukaryota; Guanine; Humans; Invertebrates; Purines; Theobromine; Theophylline | 1953 |
Toxicity of caffeine, theobromine and theophylline.
Topics: Caffeine; Diuretics; Humans; Theobromine; Theophylline | 1953 |
Investigation of complexes formed in solution by caffeine. VI. Comparison of complexing behaviors of methylated xanthines with p-aminobenzoic acid, salicylic acid, acetylsalicylic acid, and p-hydroxybenzoic acid.
Topics: 4-Aminobenzoic Acid; Aspirin; Benzoates; Caffeine; Hydroxybenzoates; Pharmaceutical Solutions; Salicylic Acid; Solutions; Theobromine; Theophylline; Xanthines | 1954 |
Action of purine alkaloids and caffeine drugs on hyaluronidase.
Topics: Caffeine; Coffee; Hyaluronoglucosaminidase; Plants; Tea; Theobromine; Theophylline | 1954 |
[Studies on the theophylline content in tea leaves].
Topics: Humans; Tea; Theobromine; Theophylline | 1956 |
[Pharmacology of water-soluble theobromine derivatives].
Topics: Theobromine; Theophylline; Water | 1956 |
[Comparative experiments on new, water-soluble derivatives of theobromine and theophylline].
Topics: Theobromine; Theophylline; Water | 1956 |
[Effect of theophylline, caffeine and theobromine on contraction force, excitability refractory period and spontaneous frequency in isolated cat myocardium].
Topics: Animals; Caffeine; Cats; Felis; Heart; Myocardium; Theobromine; Theophylline | 1956 |
[Contractile action of methylxanthines].
Topics: Caffeine; Humans; Muscle Contraction; Theobromine; Theophylline; Xanthines | 1957 |
A study of the metabolism of theobromine, theophylline, and caffeine in man.
Topics: Body Fluids; Caffeine; Humans; Male; Theobromine; Theophylline | 1957 |
Complexes formed in solution by homologs of caffeine; interactions between p-hydroxybenzoic acid and ethyl, propyl, and butyl derivatives of theobromine, and theophylline.
Topics: Caffeine; Hydroxybenzoates; Pharmaceutical Solutions; Solutions; Theobromine; Theophylline | 1957 |
[Effect of new theophylline and theobromine derivatives on the contracting power of the heart muscle].
Topics: Blood Vessels; Humans; Myocardium; Theobromine; Theophylline | 1958 |
[Rational heart therapy with digoxin-purine body combinations].
Topics: Adenosine; Digoxin; Diuretics; Heart Diseases; Humans; Purines; Theobromine; Theophylline | 1959 |
[Aminolysis of epoxides. III. Preparation of beta-hydroxyalkyl-dimethyl-purines; double decomposition of theophylline & theobromine with 1,2-epoxides].
Topics: Epoxy Compounds; Purines; Theobromine; Theophylline | 1959 |
[Therapy of heart disease in the aged with a new theophylline-theobromine combination].
Topics: Aged; Heart Diseases; Humans; Theobromine; Theophylline | 1959 |
[The action of caffeine, theobromine and theophylline on the isolated phrenicus-diaphragm preparation of the rat in different extracellular concentrations of potassium and calcium ions].
Topics: Abdominal Muscles; Animals; Caffeine; Calcium; Calcium, Dietary; Diaphragm; Ions; Muscles; Potassium; Rats; Theobromine; Theophylline | 1961 |
[Some aspects of the pharmacological activity of a new theophylline: 1-hexyl-3, 7-dimethylxanthine (SK-7)].
Topics: Humans; Theobromine; Theophylline | 1960 |
[Studies on the coulometric determination of caffeine, theobromine and theophylline. I. Chlorocoulometric microdetermination of caffeine].
Topics: Caffeine; Theobromine; Theophylline | 1963 |
[Some possibilities for the use of thin-layer chromatography without binding agents in drug analysis. 3. Qualitative detection of purines and barbiturates used in prescriptions].
Topics: Aminophylline; Barbiturates; Caffeine; Chromatography, Thin Layer; Phenobarbital; Purines; Substance Abuse Detection; Theobromine; Theophylline | 1963 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
[STUDIES ON THE SYNTHESES OF XANTHINE DERIVATIVES. V. SYNTHESES OF SOME 7-(2-HYDROXY-3-ALKYLAMINOPROPYL)THEOPHYLINE AND 1-(2-HYDROXY-3-ALKYLAMINOPROPYL)THEOBROMINE AND THEIR DERIVATIVES].
Topics: Chemistry, Pharmaceutical; Coronary Disease; Pharmacology; Pharmacy; Pregnenes; Research; Theobromine; Theophylline; Vasodilator Agents; Xanthine; Xanthines | 1963 |
[EFFECTS OF VARIOUS NATURAL ORGANIC SUBSTANCES AND AMINO ACIDS ON THE BLOOD SURGAR LEVEL AND EXPERIMENTAL STUDIES ON ORAL HYPOGLYCEMIC AGENTS].
Topics: Amino Acids; Animals; Bile Acids and Salts; Blood Chemical Analysis; Blood Glucose; Caffeine; Chlorpropamide; Creatine; Creatinine; Cystine; Diabetes Mellitus, Experimental; Hippurates; Hypoglycemic Agents; Injections; Injections, Intravenous; Metformin; Pathology; Pharmacology; Rats; Research; Salts; Theobromine; Theophylline; Tyrosine | 1963 |
MUTATIONAL SYNERGISM BETWEEN RADIATIONS AND METHYLATED PURINES IN ESCHERICHIA COLI.
Topics: Caffeine; Escherichia coli; Light; Mutation; Pharmacology; Purines; Research; Streptomycin; Theobromine; Theophylline; Ultraviolet Rays | 1964 |
[CURRENT THERAPEUTIC METHODS IN THE THOROUGH TREATMENT OF ASTHMA].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Allergic Agents; Asthma; Bloodletting; Child; Climate; Cortisone; Desensitization, Immunologic; gamma-Globulins; Histamine H1 Antagonists; Humans; Hyperthermia, Induced; Immunotherapy, Active; Mineral Waters; Penicillins; Progesterone; Psychotherapy; Radiotherapy; Respiratory Therapy; Surgical Procedures, Operative; Testosterone; Tetracycline; Theobromine; Theophylline | 1963 |
[TERTIARY AND QUATERNARY BASES DERIVED FROM XANTHINIC DIOXOLANES].
Topics: Dioxolanes; Heterocyclic Compounds; Research; Theobromine; Theophylline | 1963 |
DEMETHYLATION OF PURINE ANALOGS BY MICROSOMAL ENZYMES FROM MOUSE LIVER.
Topics: Animals; Antimetabolites; Caffeine; Carcinoma; Carcinoma, Ehrlich Tumor; Liver; Mercaptopurine; Metabolism; Mice; Purines; Pyrimidines; Research; Sulfhydryl Compounds; Theobromine; Theophylline | 1964 |
[THERAPEUTIC POSSIBILITIES IN TINNITUS].
Topics: Acetazolamide; Blood Vessels; Calcium; Glucose; Hearing Disorders; Humans; Injections; Iodine; Nerve Endings; Niacin; Nicotinic Acids; Pharmaceutical Preparations; Physiology; Procaine; Theobromine; Theophylline; Tinnitus; Toxicology | 1964 |
THE ANTI-ANAPHYLACTIC ACTIVITY OF THEOPHYLLINE AND SOME RELATED XANTHINE DERIVATIVES.
Topics: Anaphylaxis; Anti-Allergic Agents; Caffeine; Diuretics; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Lipids; Lung; Pharmacology; Research; Theobromine; Theophylline; Xanthine; Xanthines | 1964 |
THE DYE-SENSITIZED PHOTOOXIDATION OF PURINE AND PYRIMIDINE DERIVATIVES.
Topics: Caffeine; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Infrared Rays; Light; Manometry; Methylene Blue; Nucleosides; Oxidation-Reduction; Purines; Research; Theobromine; Theophylline; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uric Acid; Xanthines | 1964 |
MECHANISM OF MELANOPHORE DISPERSION.
Topics: Adrenocorticotropic Hormone; Animals; Anura; Arsenicals; Benzoates; Caffeine; Calcium Chloride; Chromatophores; Cyanides; Fluoroacetates; Glyceraldehyde; Iodoacetates; Melanocyte-Stimulating Hormones; Melanophores; Mercury; Norepinephrine; Pharmacology; Pigmentation; Potassium; Research; Theobromine; Theophylline | 1964 |
[THE EFFECT OF 7-(2-HYDROXY-3-(N-2-HYDROXYETHYL-N-METHYLAMINO)-PROPYL-THEOPHYLLINE NICOTINATE AND OTHER PURINE BODIES ON THE RESPIRATION AND ELECTROCARDIOGRAM OF GUINEA PIGS AND RATS IN HISTOTOXIC OXYGEN DEFICIENCY].
Topics: Cyanides; Electrocardiography; Guinea Pigs; Hypoxia; Niacin; Nicotinic Acids; Oxygen; Pharmacology; Potassium; Purines; Rats; Research; Respiration; Theobromine; Theophylline; Toxicology | 1963 |
ASSIGNMENT OF THE N-METHYL HYDROGEN NMR PEAKS OF CAFFEINE.
Topics: Caffeine; Chemistry, Pharmaceutical; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pharmacy; Research; Theobromine; Theophylline | 1964 |
EFFECT OF XANTHINES AND HISTAMINE ON ION TRANSPORT AND RESPIRATION BY FROG GASTRIC MUCOSA.
Topics: Anura; Caffeine; Chlorides; Epithelium; Fatty Acids; Gastric Juice; Gastric Mucosa; Glucuronates; Histamine; Ion Exchange; Ion Transport; Metabolism; Muscle, Smooth; Pharmacology; Research; Stomach; Theobromine; Theophylline; Xanthines | 1965 |
ON THE RELATIONSHIP BETWEEN LIPID SOLUBILITY AND MICROSOMAL METABOLISM OF DRUGS.
Topics: Animals; Barbiturates; Lipids; Liver; Metabolism; Mice; Microsomes; Nucleosides; Purines; Puromycin; Pyrimidines; Rats; Research; Solubility; Theobromine; Theophylline; Thiazoles; Tyrosine | 1965 |
[STUDIES ON THE COULOMETRIC DETERMINATION OF CAFFEINE, THEOBROMINE AND THEOPHYLLINE. V. CHLOROCOULOMETRIC MICRODETERMINATION OF THEOPHYLLINE AFTER ALKALINE HYDROLYSIS].
Topics: Caffeine; Hydrolysis; Research; Theobromine; Theophylline | 1964 |
[STUDIES ON THE COULOMETRIC DETERMINATION OF CAFFEINE, THEOBROMINE AND THEOPHYLLINE. VI. CHLOROCOULOMETRIC MICRODETERMINATION OF COMPONENTS IN A MIXTURE OF CAFFEINE, THEOPHYLLINE AND THEOBROMINE].
Topics: Caffeine; Research; Theobromine; Theophylline | 1964 |
[STUDIES ON THE COULOMETRIC DETERMINATION OF CAFFEINE, THEOBROMINE AND THEOPHYLLINE. 3. CHLORO-COULOMETRIC MICRODETERMINATION OF CAFFEINE AFTER ITS ALKALINE HYDROLYSIS WITH THE USE OF 2 METHODS].
Topics: Caffeine; Chemistry Techniques, Analytical; Hydrolysis; Microchemistry; Research; Theobromine; Theophylline | 1964 |
[STUDIES ON THE COULOMETRIC DETERMINATION OF CAFFEINE, THEOBROMINE AND THEOPHYLLINE. IV. BROMO-COULOMETRIC MICRODETERMINATION OF CAFFEINE AFTER ALKALINE HYDROLYSIS].
Topics: Caffeine; Chemistry Techniques, Analytical; Hydrolysis; Microchemistry; Research; Theobromine; Theophylline | 1964 |
EFFECT OF NATURALLY OCCURRING XANTHINES ON BACTERIA. I. ANTIMICROBIAL ACTION AND POTENTIATING EFFECT ON ANTIBIOTIC SPECTRA.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacillus subtilis; Bacteria; Caffeine; Candida; Citrates; Corynebacterium diphtheriae; Enterobacter; Enterobacter aerogenes; Escherichia coli; Klebsiella; Mycobacterium; Pharmacology; Proteus; Pseudomonas aeruginosa; Research; Salmonella paratyphi A; Salmonella typhi; Sarcina; Shigella dysenteriae; Staphylococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Streptomycin; Tetracycline; Theobromine; Theophylline; Xanthines | 1965 |
[Henodynamic effect of purine bodies in unanesthetized dog; comparative studies on caffeine, theobromine, theophylline, euphylline, hydroxyethyltheophylline and dihydroxypropyltheophylline].
Topics: Aminophylline; Animals; Caffeine; Dogs; Dyphylline; Ethylenediamines; Purines; Theobromine; Theophylline; Xanthines | 1955 |
Effects of coffee components on the response of GABA(A) receptors expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Cattle; Coffea; Drug Synergism; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Oocytes; Plant Extracts; Receptors, GABA-A; Theobromine; Theophylline; Xenopus laevis | 2003 |
[Comparison of the effect of some puric alkaloids (caffeine, theobromine, theophylline and theophylline-ethylenediamine) on cholinesterase].
Topics: Alkaloids; Aminophylline; Caffeine; Cholinesterases; Humans; Theobromine; Theophylline | 1950 |
[Argentometric determination of theophylline and theobromine].
Topics: Humans; Theobromine; Theophylline | 1950 |
The effect of methylxanthines on the hypocoagulability induced by chloroform in the dog.
Topics: Animals; Caffeine; Chloroform; Dogs; Hemostatics; Prothrombin; Theobromine; Theophylline; Xanthines | 1952 |
Automated sample preparation based on the sequential injection principle. Solid-phase extraction on a molecularly imprinted polymer coupled on-line to high-performance liquid chromatography.
Topics: Automation; Caffeine; Chromatography, High Pressure Liquid; Polymers; Theobromine; Theophylline | 2004 |
The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System; Synaptic Transmission; Theobromine; Theophylline; Triazines; Triazoles | 2004 |
Determination of caffeine, theobromine, and theophylline in standard reference material 2384, baking chocolate, using reversed-phase liquid chromatography.
Topics: Cacao; Caffeine; Chromatography, High Pressure Liquid; Reference Standards; Theobromine; Theophylline | 2004 |
Simultaneous determination of caffeine, theophylline and theobromine in human plasma by on-line solid-phase extraction coupled to reversed-phase chromatography.
Topics: Buffers; Caffeine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Methanol; Phosphates; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Theobromine; Theophylline | 2004 |
An ultraviolet spectrophotometric method for the determination of theophylline and theobromine in blood and tissues.
Topics: Humans; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 1949 |
[Methylxanthines in the group of potassium sensitizers].
Topics: Caffeine; Humans; Nervous System Physiological Phenomena; Physiology; Potassium; Theobromine; Theophylline; Xanthines | 1950 |
Vibrational spectral investigation on xanthine and its derivatives--theophylline, caffeine and theobromine.
Topics: Caffeine; Carbon; Hydrogen; Kinetics; Molecular Structure; Nitrogen; Oxygen; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Theobromine; Theophylline; Vibration; Xanthines | 2005 |
Raman spectroscopic characterisations and analytical discrimination between caffeine and demethylated analogues of pharmaceutical relevance.
Topics: Alkaloids; Caffeine; Models, Chemical; Spectroscopy, Fourier Transform Infrared; Theobromine; Theophylline; Xanthine | 2005 |
Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine.
Topics: 3-O-Methylglucose; Adenosine; Adenosine Monophosphate; Animals; Colforsin; Female; Glucose; Intestinal Absorption; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Signal Transduction; Sodium-Glucose Transporter 1; Stimulation, Chemical; Theobromine; Theophylline | 2005 |
Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites.
Topics: Animals; Biological Transport; Caffeine; CHO Cells; Cricetinae; Cricetulus; Humans; Molecular Structure; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Theobromine; Theophylline; Uric Acid; Xanthines | 2005 |
Study for luminescence performance of three methyl xanthine derivatives.
Topics: Caffeine; Fluorescence; Hydrogen-Ion Concentration; Luminescent Measurements; Molecular Structure; Spectrometry, Fluorescence; Temperature; Theobromine; Theophylline; Xanthines | 2005 |
Comment on vibrational spectral investigation on xanthine and its derivatives-theophylline, caffeine and theobromine.
Topics: Caffeine; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Theobromine; Theophylline; Vibration | 2005 |
In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana.
Topics: Adhesives; Administration, Cutaneous; Animals; Caffeine; Catechin; In Vitro Techniques; Paullinia; Plant Extracts; Polyethylene Glycols; Propylene Glycol; Skin; Skin Absorption; Swine; Theobromine; Theophylline; Water | 2006 |
Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction.
Topics: Adult; Biomarkers; Caffeine; Chi-Square Distribution; Connecticut; Cytochrome P-450 Enzyme System; Female; Fetal Blood; Fetal Growth Retardation; Humans; Massachusetts; Maternal-Fetal Exchange; Mothers; Pregnancy; Pregnancy Outcome; Risk Factors; Statistics, Nonparametric; Theobromine; Theophylline | 2006 |
Regulation of the body fat percentage in developmental-stage rats by methylxanthine derivatives in a high-fat diet.
Topics: Abdominal Fat; Animals; Body Weight; Caffeine; Cholesterol; Diet; Dietary Fats; Eating; Liver; Male; Rats; Rats, Sprague-Dawley; Theobromine; Theophylline; Triglycerides; Xanthines | 2006 |
Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentration.
Topics: Animals; Blood-Brain Barrier; Brain; Drug Evaluation, Preclinical; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Theobromine; Theophylline | 2006 |
Fluid bed drying of guarana (Paullinia cupana HBK) extract: effect of process factors on caffeine content.
Topics: Caffeine; Desiccation; Drug Compounding; Plant Extracts; Rheology; Theobromine; Theophylline | 2006 |
Computationally-assisted approach to the vibrational spectra of molecular crystals: study of hydrogen-bonding and pseudo-polymorphism.
Topics: Caffeine; Computer Simulation; Crystallization; Hydrogen Bonding; Models, Molecular; Molecular Structure; Spectroscopy, Fourier Transform Infrared; Theobromine; Theophylline; Vibration | 2006 |
Contribution of hepatic adenosine A1 receptors to renal dysfunction associated with acute liver injury in rats.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Chemical and Drug Induced Liver Injury; Denervation; Disease Models, Animal; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Renal Insufficiency; Sodium; Theobromine; Theophylline; Thioacetamide; Urine; Xanthines | 2006 |
Transdermal and buccal delivery of methylxanthines through human tissue in vitro.
Topics: Administration, Buccal; Administration, Cutaneous; Caffeine; Central Nervous System Stimulants; Excipients; Humans; In Vitro Techniques; Mouth Mucosa; Oleic Acid; Permeability; Skin; Skin Absorption; Solubility; Theobromine; Theophylline; Xanthenes | 2007 |
Death by chocolate: a fatal problem for an inquisitive wild parrot.
Topics: Animals; Animals, Wild; Cacao; Caffeine; Fatal Outcome; Male; Parrots; Theobromine; Theophylline; Xanthines | 2007 |
Development of in-tube solid-phase microextraction coupled to pressure-assisted CEC and its application to the analysis of propranolol enantiomers in human urine.
Topics: Caffeine; Capillary Electrochromatography; Pressure; Propranolol; Solid Phase Microextraction; Theobromine; Theophylline | 2007 |
Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humans.
Topics: Adult; Aging; Brain Injuries; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Ethanol; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Male; Prospective Studies; Theobromine; Theophylline; Treatment Outcome | 2008 |
Determination of caffeine in coffee products by dynamic complexation with 3,4-dimethoxycinnamate and separation by CZE.
Topics: Anions; Beverages; Binding Sites; Caffeine; Chlorogenic Acid; Cinnamates; Coffee; Electric Conductivity; Electrophoresis, Capillary; Hydrophobic and Hydrophilic Interactions; Kinetics; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Spectrophotometry, Ultraviolet; Theobromine; Theophylline | 2007 |
Effect of drug solubility on release behavior of calcium polysaccharide gel-coated pellets.
Topics: Alginates; Caffeine; Calcium Compounds; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Gels; Kinetics; Particle Size; Pectins; Pharmaceutical Preparations; Solubility; Surface Properties; Theobromine; Theophylline | 2007 |
Inelastic neutron scattering study of methyl groups rotation in some methylxanthines.
Topics: Caffeine; Methylation; Models, Chemical; Models, Molecular; Neutron Diffraction; Rotation; Spectrum Analysis; Theobromine; Theophylline; Thermodynamics; Xanthines | 2007 |
The spectrophotometric determination of the dissociation constants of theophylline, theobromine, and caffeine.
Topics: Caffeine; Humans; Spectrophotometry; Theobromine; Theophylline | 1949 |
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2008 |
Determination of caffeine and associated compounds in food, beverages, natural products, pharmaceuticals, and cosmetics by micellar electrokinetic capillary chromatography.
Topics: Acetaminophen; Antipyrine; Aspirin; Beverages; Biological Products; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Codeine; Cosmetics; Food Analysis; Linear Models; Pharmaceutical Preparations; Salicylic Acid; Theobromine; Theophylline | 2008 |
Simultaneous HPLC determination of caffeine, theobromine, and theophylline in food, drinks, and herbal products.
Topics: Beverages; Caffeine; Chromatography, High Pressure Liquid; Food Analysis; Plant Preparations; Theobromine; Theophylline; Xanthines | 2008 |
Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells.
Topics: Animals; Blotting, Western; Caffeine; Cells, Cultured; Connective Tissue Growth Factor; DNA Primers; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Hepatocytes; Inhibitory Concentration 50; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; Theobromine; Theophylline | 2009 |
Grafting of molecularly imprinted polymers on iniferter-modified carbon nanotube.
Topics: Binding Sites; Biosensing Techniques; Caffeine; Kinetics; Microscopy, Electron, Scanning; Molecular Imprinting; Molecular Structure; Nanotubes, Carbon; Polymers; Theobromine; Theophylline | 2009 |
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2009 |
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines | 2009 |
The role of the basal forebrain adenosine receptors in sleep homeostasis.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Catheterization; Electrodes, Implanted; Electroencephalography; Homeostasis; Male; Prosencephalon; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sleep; Sleep Deprivation; Theobromine; Theophylline | 2009 |
The interaction of lysozyme with caffeine, theophylline and theobromine in solution.
Topics: Animals; Binding Sites; Caffeine; Chickens; Energy Transfer; Kinetics; Muramidase; Protein Conformation; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Theobromine; Theophylline | 2010 |
[Rapid determination of theophylline, theobromine and caffeine in dietary supplements containing guarana by ultra-performance liquid chromatography].
Topics: Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dietary Supplements; Mass Spectrometry; Paullinia; Theobromine; Theophylline | 2009 |
The lipotropic activity of caffeine, theobromine and theophylline.
Topics: Caffeine; Lipotropic Agents; Theobromine; Theophylline | 1947 |
Rapid determination of methylxanthines in real samples by high-performance liquid chromatography using the new FastGradient narrow-bore monolithic column.
Topics: Beverages; Caffeine; Carbonated Beverages; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Coffee; Food Analysis; Food Contamination; Limit of Detection; Pharmaceutical Preparations; Reproducibility of Results; Tablets; Tea; Theobromine; Theophylline; Water; Xanthines | 2010 |
Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation.
Topics: Acridine Orange; Antineoplastic Agents; Biophysical Phenomena; Caffeine; Carcinogens; Chlorophyll; Chlorophyllides; Diet; DNA; Humans; Male; Mutagens; Neoplasms; Theobromine; Theophylline; Xanthines | 2010 |
Pharmacokinetics and metabolism of natural methylxanthines in animal and man.
Topics: Animals; Caffeine; Female; Humans; Male; Metabolic Networks and Pathways; Theobromine; Theophylline; Tissue Distribution; Xanthines | 2011 |
Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source.
Topics: Amino Acid Sequence; Bacterial Proteins; Caffeine; Carbon; Formaldehyde; Heme Oxygenase (Decyclizing); Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Weight; Nitrogen; Pseudomonas putida; Sequence Alignment; Substrate Specificity; Theobromine; Theophylline; Xanthines | 2011 |
Interactions between minimum run time, modifier concentration, and efficiency parameters in a high performance liquid chromatography separation.
Topics: Chromatography, High Pressure Liquid; Methanol; Models, Chemical; Niacinamide; Pressure; Resorcinols; Theobromine; Theophylline; Time Factors; Uracil | 2011 |
Effect of source variation on drug release from HPMC tablets: linear regression modeling for prediction of drug release.
Topics: Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Compressive Strength; Drug Compounding; Drug Design; Drug Industry; Excipients; Forecasting; Hypromellose Derivatives; Linear Models; Methylcellulose; Models, Chemical; Molecular Weight; Pharmaceutical Preparations; Solubility; Tablets; Theobromine; Theophylline; Viscosity | 2011 |
The influence of the PDE inhibitors on cough reflex in guinea pigs.
Topics: Animals; Antitussive Agents; Bronchial Hyperreactivity; Citric Acid; Cough; Guinea Pigs; Male; Ovalbumin; Phosphodiesterase Inhibitors; Reflex; Theobromine; Theophylline | 2011 |
Effects of rutaecarpine on the metabolism and urinary excretion of caffeine in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Drug Interactions; Enzyme Induction; Indole Alkaloids; Quinazolines; Rats; Rats, Sprague-Dawley; Theobromine; Theophylline; Vasodilator Agents | 2011 |
Measurements of caffeine and plasma metabolite/caffeine ratios as a test for hepatic drug-oxidizing capacity in goats.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Female; Goats; Liver; Oxidation-Reduction; Reference Standards; Theobromine; Theophylline | 2011 |
Caffeine as an indicator for the quantification of untreated wastewater in karst systems.
Topics: Biodegradation, Environmental; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Environmental Monitoring; Germany; Groundwater; Seasons; Sewage; Tandem Mass Spectrometry; Theobromine; Theophylline; Water Movements; Water Pollutants, Chemical | 2012 |
Presynaptic inhibition of GABAergic synaptic transmission by adenosine in mouse hypothalamic hypocretin neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neural Inhibition; Neuropeptides; Orexins; Patch-Clamp Techniques; Presynaptic Terminals; Purinergic Antagonists; Synaptic Transmission; Theobromine; Theophylline; Valine | 2012 |
A general strategy for performing temperature-programming in high performance liquid chromatography--further improvements in the accuracy of retention time predictions of segmented temperature gradients.
Topics: Aspartame; Caffeine; Chromatography, High Pressure Liquid; Food Additives; Linear Models; Models, Chemical; Reproducibility of Results; Rutin; Temperature; Theobromine; Theophylline | 2012 |
Development of a chromatographic low pressure flow injection system: application to the analysis of methylxanthines in coffee.
Topics: Beverages; Caffeine; Chromatography, Liquid; Coffee; Flow Injection Analysis; Food Analysis; Limit of Detection; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 2012 |
Spectral analysis of naturally occurring methylxanthines (theophylline, theobromine and caffeine) binding with DNA.
Topics: Caffeine; DNA; Spectroscopy, Fourier Transform Infrared; Theobromine; Theophylline | 2012 |
Guarana powder polysaccharides: characterisation and evaluation of the antioxidant activity of a pectic fraction.
Topics: Antioxidants; Caffeine; Paullinia; Pectins; Plant Extracts; Seeds; Theobromine; Theophylline | 2012 |
A piezoelectric drop-on-demand generator for accurate samples in capillary electrophoresis.
Topics: Bronchodilator Agents; Caffeine; Electrophoresis, Microchip; Equipment Design; Limit of Detection; Sample Size; Theobromine; Theophylline | 2013 |
Simultaneous quantification of caffeine and its three primary metabolites in rat plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Theobromine; Theophylline | 2013 |
Simultaneous determination of caffeine, theophylline and theobromine in food samples by a kinetic spectrophotometric method.
Topics: Beverages; Caffeine; Kinetics; Neural Networks, Computer; Spectrophotometry; Theobromine; Theophylline; Xanthines | 2013 |
[Evaluation of pharmacokinetic interaction of aphobazole with CYP1A2 drug-substrate in experiments].
Topics: Administration, Oral; Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Benzimidazoles; Biotransformation; Caffeine; Chromatography, Gas; Cytochrome P-450 CYP1A2; Cytochromes; Drug Administration Schedule; Drug Interactions; Male; Morpholines; Rats; Theobromine; Theophylline | 2013 |
UHPLC determination of catechins for the quality control of green tea.
Topics: Caffeine; Calibration; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Geography; Kinetics; Mass Spectrometry; Micelles; Plant Extracts; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tea; Theobromine; Theophylline | 2014 |
Molecular and biochemical characterization of caffeine synthase and purine alkaloid concentration in guarana fruit.
Topics: Alkaloids; Amino Acid Sequence; Base Sequence; Caffeine; Fruit; Methylation; Methyltransferases; Molecular Structure; Paullinia; Plant Leaves; Purines; Seeds; Theobromine; Theophylline; Xanthines | 2014 |
Methylxanthine reversal of opioid-induced respiratory depression in the neonatal rat: mechanism and location of action.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Apnea; Brain Stem; Carotid Body; Central Nervous System Stimulants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Phrenic Nerve; Quinazolines; Rats, Sprague-Dawley; Respiration; Theobromine; Theophylline; Tissue Culture Techniques; Triazoles; Xanthines | 2014 |
Associations of ambulatory blood pressure with urinary caffeine and caffeine metabolite excretions.
Topics: Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Hypertension; Male; Middle Aged; Prevalence; Theobromine; Theophylline | 2015 |
Genoprotective and hepatoprotective effects of Guarana (Paullinia cupana Mart. var. sorbilis) on CCl4-induced liver damage in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Carbon Tetrachloride; DNA Damage; Dose-Response Relationship, Drug; Hepatocytes; Liver Diseases; Male; Rats; Rats, Wistar; Silymarin; Theobromine; Theophylline | 2016 |
Synthesis and anticancer activity of silver(I)-N-heterocyclic carbene complexes derived from the natural xanthine products caffeine, theophylline and theobromine.
Topics: Antineoplastic Agents; Biological Products; Caffeine; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Hydrophobic and Hydrophilic Interactions; Methane; Molecular Conformation; Silver; Theobromine; Theophylline; Xanthine | 2015 |
Quantitative on-line concentration for capillary electrophoresis with inkjet sample introduction technique.
Topics: Caffeine; Electrophoresis, Capillary; Limit of Detection; Theobromine; Theophylline | 2015 |
Simultaneous multiplexed quantification of caffeine and its major metabolites theobromine and paraxanthine using surface-enhanced Raman scattering.
Topics: Caffeine; Humans; Limit of Detection; Machine Learning; Neural Networks, Computer; Spectrum Analysis, Raman; Surface Properties; Theobromine; Theophylline | 2015 |
Hypercholesterolemia and Ecto-enzymes of Purinergic System: Effects of Paullinia cupana.
Topics: Adenosine Deaminase; Animals; Caffeine; Cholesterol; Cholesterol, LDL; Diet, High-Fat; Hypercholesterolemia; Lymphocytes; Male; Paullinia; Plant Preparations; Rats; Rats, Wistar; Theobromine; Theophylline | 2016 |
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Interleukin-1beta; Medicine, Chinese Traditional; Mice; Monoterpenes; Motor Activity; Paclitaxel; Pain Measurement; Theobromine; Theophylline; Xanthines | 2015 |
Rapid assessment of bioactive phenolics and methylxanthines in spent coffee grounds by FT-NIR spectroscopy.
Topics: Caffeic Acids; Caffeine; Catechin; Chlorogenic Acid; Coffee; Spectroscopy, Near-Infrared; Theobromine; Theophylline; Waste Products | 2016 |
Degradation of exogenous caffeine by Populus alba and its effects on endogenous caffeine metabolism.
Topics: Biodegradation, Environmental; Caffeine; Chromatography, High Pressure Liquid; Hydroponics; Plant Leaves; Plant Roots; Plant Stems; Populus; Tandem Mass Spectrometry; Theobromine; Theophylline; Water Pollutants, Chemical | 2016 |
Correction.
Topics: Adult; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Circadian Rhythm; Cross-Sectional Studies; Female; Humans; Hypertension; Male; Middle Aged; Prevalence; Theobromine; Theophylline | 2016 |
Stepwise injection potentiometric determination of caffeine in saliva using single-drop microextraction combined with solvent exchange.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Liquid Phase Microextraction; Potentiometry; Saliva; Theobromine; Theophylline | 2016 |
[Coffee lowers in a study blood pressure].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Caffeine; Female; Humans; Male; Theobromine; Theophylline | 2015 |
Molecularly imprinted poly(4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid) modified glassy carbon electrode as an electrochemical theophylline sensor.
Topics: Caffeine; Carbon; Dielectric Spectroscopy; Electrochemical Techniques; Electrodes; Humans; Hydrogen-Ion Concentration; Limit of Detection; Microscopy, Atomic Force; Molecular Imprinting; Polymers; Theobromine; Theophylline; Tin Compounds | 2016 |
Lysozyme binding ability toward psychoactive stimulant drugs: Modulatory effect of colloidal metal nanoparticles.
Topics: Animals; Binding Sites; Chickens; Colloids; Fluorescence; Gold; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Metal Nanoparticles; Molecular Docking Simulation; Muramidase; Protein Binding; Silver; Spectrometry, Fluorescence; Theobromine; Theophylline; Vasodilator Agents | 2016 |
Control of methylxanthines in the competition horse: pharmacokinetic/pharmacodynamic studies on caffeine, theobromine and theophylline for the assessment of irrelevant concentrations.
Topics: Animals; Caffeine; Chromatography, Liquid; Horses; Theobromine; Theophylline; Xanthines | 2017 |
Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.
Topics: Antigens, CD; Basic Helix-Loop-Helix Transcription Factors; Caffeine; CD83 Antigen; Coffee; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Genome-Wide Association Study; Humans; Immunoglobulins; Male; Membrane Glycoproteins; Polymorphism, Single Nucleotide; Receptors, Aryl Hydrocarbon; Theobromine; Theophylline; White People | 2016 |
Guarana (Paullinia cupana) ameliorates memory impairment and modulates acetylcholinesterase activity in Poloxamer-407-induced hyperlipidemia in rat brain.
Topics: Acetylcholinesterase; Animals; Blood Glucose; Brain; Caffeine; Cholesterol; Hyperlipidemias; Male; Maze Learning; Paullinia; Plant Extracts; Poloxamer; Rats; Rats, Wistar; Recognition, Psychology; Statistics, Nonparametric; Surface-Active Agents; Theobromine; Theophylline | 2017 |
Magnetic Solid-phase Extraction with Fe₃O₄/Molecularly Imprinted Polymers Modified by Deep Eutectic Solvents and Ionic Liquids for the Rapid Purification of Alkaloid Isomers (Theobromine and Theophylline) from Green Tea.
Topics: Ferric Compounds; Ionic Liquids; Magnetic Phenomena; Microscopy, Electron, Scanning; Molecular Imprinting; Solid Phase Extraction; Solvents; Spectroscopy, Fourier Transform Infrared; Tea; Theobromine; Theophylline | 2017 |
Chemical profiling of guarana seeds (Paullinia cupana) from different geographical origins using UPLC-QTOF-MS combined with chemometrics.
Topics: Biflavonoids; Brazil; Caffeine; Catechin; Chromatography, High Pressure Liquid; Mass Spectrometry; Paullinia; Phenols; Proanthocyanidins; Seeds; Theobromine; Theophylline | 2017 |
Determination of caffeine, theobromine and theophylline in Mate beer and Mate soft drinks by high-performance thin-layer chromatography.
Topics: Beer; Caffeine; Carbonated Beverages; Chromatography, Thin Layer; Food Analysis; Theobromine; Theophylline | 2018 |
Poly(para-phenyleneethynylene)-Sensor Arrays Discriminate 22 Different Teas.
Topics: Alkynes; Biosensing Techniques; Caffeine; Camellia sinensis; Ethers; Plant Leaves; Tea; Theobromine; Theophylline | 2018 |
An aptamer nanopore-enabled microsensor for detection of theophylline.
Topics: Animals; Aptamers, Nucleotide; Biosensing Techniques; Bronchodilator Agents; Caffeine; Cattle; Equipment Design; Limit of Detection; Nanopores; Plant Extracts; Theobromine; Theophylline; Vasodilator Agents | 2018 |
A new insight into the oxidative mechanism of caffeine and related methylxanthines in aprotic medium: May caffeine be really considered as an antioxidant?
Topics: Antioxidants; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Solvents; Theobromine; Theophylline | 2018 |
Different Catabolism Pathways Triggered by Various Methylxanthines in Caffeine-Tolerant Bacterium
Topics: Biodegradation, Environmental; Caffeine; Drug Tolerance; Gardens; Metabolic Networks and Pathways; Pseudomonas putida; Soil; Soil Microbiology; Substrate Specificity; Tea; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines | 2018 |
Ternary deep eutectic solvent magnetic molecularly imprinted polymers for the dispersive magnetic solid-phase microextraction of green tea.
Topics: Catechin; Magnetic Fields; Molecular Imprinting; Polymers; Silicon Dioxide; Solid Phase Microextraction; Solvents; Tea; Theobromine; Theophylline | 2018 |
Guarana (Paullinia cupana Mart.) alters gut microbiota and modulates redox status, partially via caffeine in Wistar rats.
Topics: Animals; Antioxidants; Caffeine; Dysbiosis; Gastrointestinal Microbiome; Male; Oxidation-Reduction; Oxidative Stress; Paullinia; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Seeds; Theobromine; Theophylline | 2018 |
Effect of potassium chloride on the solvation behavior of caffeine, theophylline and theobromine: Volumetric, viscometric, calorimetry and spectroscopic approach.
Topics: Caffeine; Calorimetry; Magnetic Resonance Spectroscopy; Potassium Chloride; Spectrophotometry; Temperature; Theobromine; Theophylline; Thermodynamics; Viscosity; Water | 2018 |
A rapid method for the assay of methylxanthines alkaloids: Theobromine, theophylline and caffeine, in cocoa products and drugs by paper spray tandem mass spectrometry.
Topics: Cacao; Caffeine; Chromatography, High Pressure Liquid; Food Analysis; Limit of Detection; Pharmaceutical Preparations; Reproducibility of Results; Tandem Mass Spectrometry; Theobromine; Theophylline | 2019 |
Effects of hydroalcoholic and enzyme-assisted extraction processes on the recovery of catechins and methylxanthines from crude and waste seeds of guarana (Paullinia cupana).
Topics: Antioxidants; Caffeine; Catechin; Paullinia; Phenol; Plant Extracts; Seeds; Theobromine; Theophylline; Xanthines | 2019 |
Study on the interaction and antioxidant activity of theophylline and theobromine with SOD by spectra and calculation.
Topics: Antioxidants; Malondialdehyde; Molecular Docking Simulation; Spectrometry, Fluorescence; Superoxide Dismutase; Theobromine; Theophylline | 2019 |
Lipotoxicity-associated inflammation is prevented by guarana (
Topics: Adenosine; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperlipidemias; Inflammation; Lymphocytes; Male; Rats; Rats, Wistar; Simvastatin; Theobromine; Theophylline | 2021 |
Production and characterization of solid lipid microparticles loaded with guaraná (Paullinia cupana) seed extract.
Topics: alpha-Amylases; alpha-Glucosidases; Anti-Obesity Agents; Caffeine; Catechin; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Freeze Drying; Fruit; Lipase; Particle Size; Paullinia; Phenols; Plant Extracts; Seeds; Theobromine; Theophylline | 2019 |
Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve.
Topics: Caffeine; Chromatography, Liquid; Humans; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Theobromine; Theophylline | 2019 |
Protective effect of guarana-loaded liposomes on hemolytic activity.
Topics: Animals; Antioxidants; Caffeine; Drug Compounding; Hemolysis; Liposomes; Particle Size; Protective Agents; Rats; Theobromine; Theophylline | 2020 |
Revisiting the spectroscopy of xanthine derivatives: theobromine and theophylline.
Topics: Photoelectron Spectroscopy; Spectrophotometry; Theobromine; Theophylline; Xanthines | 2019 |
Solvent and temperature effect of accelerated solvent extraction (ASE) coupled with ultra-high-pressure liquid chromatography (UHPLC-PDA) for the determination of methyl xanthines in commercial tea and coffee.
Topics: Caffeine; Chromatography, High Pressure Liquid; Coffee; Sensitivity and Specificity; Solvents; Tea; Temperature; Theobromine; Theophylline; Xanthines | 2020 |
Insoluble-Bound Polyphenols Released from Guarana Powder: Inhibition of Alpha-Glucosidase and Proanthocyanidin Profile.
Topics: alpha-Glucosidases; Brazil; Caffeine; Diabetes Mellitus, Type 2; Dietary Supplements; Glycoside Hydrolase Inhibitors; Humans; Medicine, Traditional; Paullinia; Phytochemicals; Plant Extracts; Polyphenols; Proanthocyanidins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Theobromine; Theophylline | 2020 |
In vivo solid-phase microextraction swab sampling of environmental pollutants and drugs in human body for nano-electrospray ionization mass spectrometry analysis.
Topics: Caffeine; Environmental Pollutants; Human Body; Humans; Imidazoles; Mouth; Nanotechnology; Nicotine; Skin; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization; Theobromine; Theophylline | 2020 |
Chemical implications and time reduction of on-farm cocoa fermentation by Saccharomyces cerevisiae and Pichia kudriavzevii.
Topics: Amines; Cacao; Caffeine; Catechin; Chocolate; Farms; Fermentation; Food Microbiology; Hydrogen-Ion Concentration; Phenols; Pichia; Saccharomyces cerevisiae; Temperature; Theobromine; Theophylline; Time Factors | 2021 |
Exploring the Association between Urine Caffeine Metabolites and Urine Flow Rate: A Cross-Sectional Study.
Topics: Adult; Aged; Caffeine; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Nutrition Surveys; Theobromine; Theophylline; Urination | 2020 |
Simultaneous determination of theobromine, theophylline, and caffeine using a modified electrode with petal-like MnO
Topics: Caffeine; Electrodes; Manganese Compounds; Nanostructures; Oxides; Theobromine; Theophylline | 2021 |
Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells.
Topics: Alzheimer Disease; Caffeine; Cell Line, Tumor; Gene Expression Regulation; Genes, Essential; Humans; Neuroblastoma; Pentoxifylline; Principal Component Analysis; Theobromine; Theophylline; Transcription, Genetic; Xanthines | 2020 |
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Topics: Animals; Caffeine; Cosmetics; Eating; Humans; Risk Assessment; Theobromine; Theophylline; Toxicity Tests; Xanthines | 2021 |
[Determination of Caffeine, Theobromine, and Theophylline in Chocolate Using LC-MS].
Topics: Caffeine; Chocolate; Chromatography, Liquid; Reproducibility of Results; Tandem Mass Spectrometry; Theobromine; Theophylline | 2021 |
Investigating the Relations Between Caffeine-Derived Metabolites and Plasma Lipids in 2 Population-Based Studies.
Topics: Adult; Belgium; Caffeine; Cholesterol; Cholesterol, HDL; Chromatography, High Pressure Liquid; Female; Humans; Lipids; Male; Middle Aged; Switzerland; Tandem Mass Spectrometry; Theobromine; Theophylline; Triglycerides; Xanthines | 2021 |
Simultaneous determination of caffeine and its metabolites in rat plasma by UHPLC-MS/MS.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry; Theobromine; Theophylline; Uric Acid | 2021 |
Urinary caffeine and caffeine metabolites, asthma, and lung function in a nationwide study of U.S. adults.
Topics: Adult; Asthma; Bronchodilator Agents; Caffeine; Coffee; Cross-Sectional Studies; Humans; Lung; Nutrition Surveys; Theobromine; Theophylline | 2022 |
Finger sweat analysis enables short interval metabolic biomonitoring in humans.
Topics: Adult; Biological Monitoring; Biotransformation; Caffeine; Chlorogenic Acid; Chromatography, Liquid; Coffee; Female; Fingers; Humans; Male; Metabolomics; Middle Aged; Principal Component Analysis; Sweat; Tandem Mass Spectrometry; Theobromine; Theophylline | 2021 |
Maternal caffeine intake and DNA methylation in newborn cord blood.
Topics: Adult; Caffeine; DNA Methylation; Epigenesis, Genetic; Female; Fetal Blood; Gestational Age; Humans; Infant, Newborn; Male; Maternal Exposure; Middle Aged; Pregnancy; Theobromine; Theophylline | 2022 |
Selection of Aptamers for Sensing Caffeine and Discrimination of Its Three Single Demethylated Analogues.
Topics: Beverages; Caffeine; Calorimetry; Humans; Oligonucleotides; Theobromine; Theophylline | 2022 |
The analysis of methylxanthine fractions obtained from Camellia sinensis cultivated in Turkey and effects on the in vitro inhibition of CYP2D6 enzyme.
Topics: Caffeine; Camellia sinensis; Cytochrome P-450 CYP2D6; Tea; Theobromine; Theophylline; Turkey | 2023 |
Methylxanthines Induce a Change in the AD/Neurodegeneration-Linked Lipid Profile in Neuroblastoma Cells.
Topics: Alzheimer Disease; Caffeine; Cell Line, Tumor; Cholesterol; Humans; Lipids; Neural Stem Cells; Neuroblastoma; Neurodegenerative Diseases; Pentoxifylline; Theobromine; Theophylline; Triglycerides; Xanthines | 2022 |
Caffeine, Paraxanthine, Theophylline, and Theobromine Content in Human Milk.
Topics: Caffeine; Chromatography, Liquid; Female; Humans; Milk, Human; Tandem Mass Spectrometry; Theobromine; Theophylline | 2022 |
Simultaneous quantification of caffeine and its main metabolites by gas chromatography mass spectrometry in horse urine.
Topics: Animals; Caffeine; Gas Chromatography-Mass Spectrometry; Horses; Solid Phase Extraction; Theobromine; Theophylline | 2022 |
Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC-ESI-MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water as a surrogate matrix.
Topics: Animals; Apnea; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature; Rats; Tandem Mass Spectrometry; Theobromine; Theophylline; Water | 2022 |
New light on the use of
Topics: Belize; Cacao; Clay; Guatemala; History, Ancient; Seeds; Theobromine; Theophylline | 2022 |