theophylline has been researched along with suramin in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.56) | 18.7374 |
| 1990's | 20 (51.28) | 18.2507 |
| 2000's | 13 (33.33) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Edwards, GA; Hoyle, CH | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Buchou, T; Charollais, RH; Fagot, D; Mester, J | 1 |
| Hollingsworth, M; Piper, AS | 3 |
| Bohmann, C; Rump, LC; Schaible, U; von Kügelgen, I | 1 |
| Bailey, SJ; Hourani, SM | 1 |
| Burnstock, G; Vials, AJ | 1 |
| Bjur, RA; Hashimoto, T; Hattori, K; Ishii, R; Shinozuka, K; Takeuchi, K; Westfall, DP | 1 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L | 1 |
| Lupichuk, SM; Tabrizchi, R | 1 |
| Dale, N; Gilday, D | 1 |
| Burnstock, G; Hoyle, CH; Pintor, J; Ziganshin, AU | 1 |
| Chen, YH; Fu, WM; Lee, KF; Liou, JC | 1 |
| Begnini, J; Bellot, RG; De-La-Vega, DD; Frussa-Filho, R; Jimenez-Bernal, RE; Lopes, FP; Mello, CF; Schwartz, CC | 1 |
| Brodie, MJ; Ross, FM; Stone, TW | 1 |
| Edwards, FA; Robertson, SJ | 1 |
| Kang, Y; McCarthy, M; Neary, JT; Zuniga, S | 1 |
| Boeynaems, JM; Communi, D; Robaye, B | 1 |
| Nikbakht, MR; Stone, TW | 2 |
| Spyer, KM; Thomas, T | 1 |
| O'Kane, EM; Stone, TW | 1 |
| Ralevic, V | 1 |
| Bültmann, R; Starke, K | 1 |
| Imamura, H; Kido, M; Lu, K; Ninomiya, H; Otani, H; Uchiyama, T | 1 |
| Héja, L; Kardos, J; Kovács, I; Lasztóczi, B; Sági, G; Szárics, E | 1 |
| Arvola, L; Bertelsen, G; Hassaf, D; Ytrehus, K | 1 |
| Burnstock, G; Grishin, SN; Kamaliev, RR; Zefirov, AL; Ziganshin, AU; Ziganshina, LE | 1 |
| Neary, JT; Washburn, KB | 1 |
| Andersson, M; Aronsson, P; Ericsson, T; Giglio, D | 1 |
| Grishin, SN; Kamaliev, RR; Teplov, AY; Ziganshin, AU | 1 |
| Gabdrakhmanov, AI; Grishin, SN; Khairullin, AE; Ziganshin, AU; Ziganshin, BA; Ziganshina, LE; Zobov, VV | 1 |
39 other study(ies) available for theophylline and suramin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Activation of P1- and P2Y-purinoceptors by ADP-ribose in the guinea-pig taenia coli, but not of P2X-purinoceptors in the vas deferens.
Topics: Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Apamin; Colon; Dipyridamole; Guinea Pigs; Male; Receptors, Purinergic; Suramin; Theophylline; Triazines; Vas Deferens | 1992 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
ATP modulates the efferent function of capsaicin-sensitive neurones in guinea-pig isolated atria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Neurons, Efferent; Receptors, Purinergic; Suramin; Theophylline | 1992 |
Mitogenic activity of phorbol esters and insulin-like growth factor 1 in chemically transformed mouse fibroblasts BP-A31: independent effects and differential sensitivity to inhibition by 3-isobutyl-1-methyl xanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Insulin; Insulin-Like Growth Factor I; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Somatomedins; Suramin; Tetradecanoylphorbol Acetate; Theophylline | 1989 |
The purinoceptors of the guinea-pig isolated taenia caeci.
Topics: Adenosine; Animals; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Theophylline | 1995 |
Alpha-adrenoceptor modulation of norepinephrine and ATP release in isolated kidneys of spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Hypertension; Kidney; Norepinephrine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Suramin; Tetrodotoxin; Theophylline; Yohimbine | 1995 |
Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladder.
Topics: Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Muscle Contraction; Muscle, Smooth; Organ Specificity; Receptors, Purinergic P2; Suramin; Theophylline; Thionucleotides; Urinary Bladder; Vas Deferens | 1994 |
The effect of suramin on vasodilator responses to ATP and 2-methylthio-ATP in the Sprague-Dawley rat coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Vessels; Drug Interactions; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Perfusion; Rats; Rats, Sprague-Dawley; Suramin; Theophylline; Thionucleotides; Vasodilation; Vasodilator Agents | 1994 |
Purinergic facilitation of norepinephrine release from adrenergic nerves of rabbit ear artery.
Topics: 2-Chloroadenosine; Adenosine Triphosphate; Animals; Arteries; Ear, External; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptors, Purinergic; Regional Blood Flow; Suramin; Sympathetic Nervous System; Theophylline | 1993 |
Blockade of adenosine receptors unmasks a stimulatory effect of ATP on cardiac contractility.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Stimulation, Chemical; Suramin; Theophylline; Triazines; Xanthines | 1993 |
Vasodilatation produced by adenosine in isolated rat perfused mesenteric artery: a role for endothelium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Glyburide; Male; Mesenteric Arteries; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Suramin; Theobromine; Theophylline; Vasodilation; Vasodilator Agents | 1995 |
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spasm; Suramin; Theophylline; Thioinosine; Thionucleotides; Uridine Triphosphate; Uterus | 1996 |
Regulation of rhythmic movements by purinergic neurotransmitters in frog embryos.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Culture Techniques; Embryo, Nonmammalian; Glutamic Acid; Ion Channel Gating; Motor Neurons; Movement; N-Methylaspartate; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spinal Cord; Suramin; Swimming; Synapses; Theophylline; Xenopus | 1996 |
The activation of P1- and P2-purinoceptors in the guinea-pig left atrium by diadenosine polyphosphates.
Topics: Analysis of Variance; Animals; Depression, Chemical; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Male; Myocardial Contraction; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Thioinosine; Trachea | 1996 |
Regulation of quantal transmitter secretion by ATP and protein kinases at developing neuromuscular synapses.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine Triphosphate; Animals; Cells, Cultured; Coculture Techniques; Embryo, Nonmammalian; Enzyme Inhibitors; Evoked Potentials; Kinetics; Muscle, Skeletal; Neuromuscular Junction; Neurons; Protein Kinases; Quantum Theory; Suramin; Synapses; Synaptic Transmission; Theophylline; Triazines; Xenopus laevis | 1997 |
Antinociceptive effect of purine nucleotides.
Topics: Analgesics; Animals; Caffeine; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Purine Nucleotides; Quinidine; Receptors, Purinergic P1; Receptors, Purinergic P2; Rosaniline Dyes; Suramin; Theophylline | 1996 |
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline | 1998 |
ATP and glutamate are released from separate neurones in the rat medial habenula nucleus: frequency dependence and adenosine-mediated inhibition of release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Aniline Compounds; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Habenula; Male; Neurons; Nucleotidases; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, Purinergic P1; Suramin; Synaptic Transmission; Synaptic Vesicles; Theophylline | 1998 |
Mitogenic signaling from P1 and P2 purinergic receptors to mitogen-activated protein kinase in human fetal astrocyte cultures.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Astrocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Activation; Fetus; Humans; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2; Signal Transduction; Suramin; Theophylline | 1998 |
Pharmacological characterization of the human P2Y11 receptor.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol 1,4,5-Trisphosphate; Phosphoadenosine Phosphosulfate; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Theophylline; Thionucleotides; Time Factors; Triazines; Tumor Cells, Cultured | 1999 |
Suramin-sensitive suppression of paired-pulse inhibition by adenine nucleotides in rat hippocampal slices.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Hippocampus; Male; Nerve Tissue Proteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
ATP as a mediator of mammalian central CO2 chemoreception.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Chemoreceptor Cells; Dose-Response Relationship, Drug; Iontophoresis; Male; Medulla Oblongata; Microelectrodes; Neurons; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Suramin; Theophylline | 2000 |
Complex hippocampal responses to ATP: fade due to nucleotidase inhibition and P2-receptor-mediated adenosine release.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Enzyme Inhibitors; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Characterisation of ATP-induced facilitation of transmission in rat hippocampus.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Caffeine; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Theophylline | 2000 |
Mechanism of prolonged vasorelaxation to ATP in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Animals; Capsaicin; Cardiotonic Agents; Cardiovascular Agents; Charybdotoxin; Drug Interactions; Electric Stimulation; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Mesenteric Arteries; Neurons, Afferent; Ouabain; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Tetraethylammonium; Theophylline; Vasodilation | 2001 |
Nucleotide-evoked relaxation of rat vas deferens--a possible role for endogenous ATP released upon alpha(1)-adrenoceptor stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Norepinephrine; Nucleotides; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Pyrophosphatases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Suramin; Theophylline; Thionucleotides; Triazines; Vas Deferens; Vasoconstrictor Agents | 2001 |
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure | 2002 |
Characterisation of an uridine-specific binding site in rat cerebrocortical homogenates.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Bromouracil; Cell Fractionation; Cerebral Cortex; Dizocilpine Maleate; Kainic Acid; Kinetics; Male; Rats; Rats, Wistar; Suramin; Synaptic Membranes; Theophylline; Uridine | 2003 |
Positive inotropic and sustained anti-beta-adrenergic effect of diadenosine pentaphosphate in human and guinea pig hearts. Role of dinucleotide receptors and adenosine receptors.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dinucleoside Phosphates; Female; Guinea Pigs; Heart Atria; Humans; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Purinergic Antagonists; Receptors, Purinergic P2; Suramin; Theophylline; Vasoconstrictor Agents | 2004 |
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Potassium Chloride; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana ridibunda; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Temperature; Theophylline | 2005 |
P2 purinergic receptors signal to STAT3 in astrocytes: Difference in STAT3 responses to P2Y and P2X receptor activation.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Serine; Signal Transduction; STAT3 Transcription Factor; Suramin; Theophylline; Thymidine; Time Factors; Tritium; Uridine Triphosphate | 2006 |
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Antagonism; Electric Stimulation; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Theophylline; Uracil Nucleotides; Urinary Bladder; Xanthines | 2010 |
Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Rana ridibunda; Receptors, Purinergic P1; Signal Transduction; Suramin; Theophylline | 2011 |
Effects of ATP and adenosine on contraction amplitude of rat soleus muscle at different temperatures.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Hypothermia; Male; Muscle Contraction; Muscle, Skeletal; Nicotinic Antagonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Temperature; Theophylline; Tubocurarine | 2017 |