theophylline and rifampin

theophylline has been researched along with rifampin in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (39.47)	18.7374
1990's	4 (10.53)	18.2507
2000's	8 (21.05)	29.6817
2010's	11 (28.95)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Iwainsky, H; Wiesner, B; Winsel, K	1
Polk, RE	1
Adebayo, GI; Akintonwa, A; Mabadeje, AF	1
Baciewicz, AM	1
Harman, EM	1
Crepaldi, G; Jemmolo, RM; Lirussi, F; Muraca, M; Nassuato, G; Okolicsanyi, L; Orlando, R; Strazzabosco, M	1
Baciewicz, AM; Bekemeyer, WB; Self, TH	1
van Assendelft, AH	1
Dal Negro, R; De Conti, F; Trevisan, F; Turco, P	1
Halawa, B	1
Marney, SR	1
Gray, BJ; Jamieson, AP; Moxham, J; Powell-Jackson, PR; Williams, R	1
Kleitke, B; Wollenberger, A	1
Birkett, DJ; Miners, JO; Robson, RA; Wing, LM	1
Henderson, RP; Lieberman, PL; Self, TH; Straughn, AB	1
Self, MM; Self, TH; Straughn, AB; Taylor, WS; Worden, JP	1
Narang, RK; Rajagopalan, PT; Rao, S; Singh, SK	1
Bachmann, KA; Jauregui, L	1
Bruzzese, VL; Gillum, JG; Israel, DS; Polk, RE; Sesler, JM	1
Adedoyin, A; Branch, RA; Frye, RF; Romkes, M; Wilson, JW	1
Ahn, HC; Lee, YC	1
Akamatsu, T; Chida, K; Inui, N; Karayama, M; Namiki, N; Tanaka, S; Uchida, S; Watanabe, H	1

Reviews

6 review(s) available for theophylline and rifampin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Clinical pharmacology in optimization of therapy of lung diseases]. Zeitschrift fur Erkrankungen der Atmungsorgane, 1991, Volume: 177, Issue:1-2 Topics: Antitubercular Agents; Asthma; Biotransformation; Ethionamide; Humans; Isoniazid; Metabolic Clearance Rate; Rifampin; Theophylline; Tuberculosis, Pulmonary	1991
Drug-drug interactions with ciprofloxacin and other fluoroquinolones. The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A Topics: Antacids; Caffeine; Ciprofloxacin; Cyclosporins; Drug Interactions; Humans; Intestinal Absorption; Rifampin; Theophylline	1989
Oral contraceptive drug interactions. Therapeutic drug monitoring, 1985, Volume: 7, Issue:1 Topics: Acetaminophen; Anti-Anxiety Agents; Anti-Bacterial Agents; Benzodiazepines; Contraceptives, Oral; Drug Interactions; Female; Glucocorticoids; Humans; Kinetics; Male; Pregnancy; Rifampin; Theophylline	1985
The effect of drugs on bile flow and composition. An overview. Drugs, 1986, Volume: 31, Issue:5 Topics: Animals; Bile; Bile Acids and Salts; Cats; Chlorpromazine; Cholagogues and Choleretics; Cholesterol; Clofibrate; Colchicine; Cricetinae; Dehydrocholic Acid; Diuretics; Dogs; Enterohepatic Circulation; Estrogens; Glucagon; Guinea Pigs; Humans; Insulin; Liver; Macaca mulatta; Phospholipids; Rabbits; Rats; Rifampin; Rifamycins; Somatostatin; Theophylline; Ursodeoxycholic Acid	1986
Asthma: recent developments in treatment. Southern medical journal, 1985, Volume: 78, Issue:9 Topics: Acute Disease; Aminophylline; Aspirin; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Budesonide; Calcium Channel Blockers; Cromolyn Sodium; Humans; Parasympatholytics; Pregnenediones; Rifampin; Theophylline	1985

Trials

4 trial(s) available for theophylline and rifampin

Article	Year
Effect of rifampicin on theophylline pharmacokinetics in human beings. The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:11 Topics: Adult; Drug Synergism; Humans; Middle Aged; Rifampin; Theophylline	1994
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid	1993
Induction of theophylline clearance by rifampin and rifabutin in healthy male volunteers. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:8 Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2; Enzyme Induction; Humans; Male; Rifabutin; Rifampin; Theophylline	1996
The clearance of theophylline is increased during the initial period of tuberculosis treatment. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2003, Volume: 7, Issue:6 Topics: Adult; Aged; Antitubercular Agents; Bronchodilator Agents; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Theophylline; Time Factors; Tuberculosis, Pulmonary	2003

Other Studies

28 other study(ies) available for theophylline and rifampin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Attenuation of rifampicin-induced theophylline metabolism by diltiazem/rifampicin coadministration in healthy volunteers. European journal of clinical pharmacology, 1989, Volume: 37, Issue:2 Topics: Adult; Diltiazem; Half-Life; Humans; Male; Rifampin; Theophylline	1989
Pulmonary problems of pregnancy. Comprehensive therapy, 1985, Volume: 11, Issue:5 Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Drug Therapy, Combination; Ethambutol; Female; Heparin; Humans; Infant, Newborn; Isoniazid; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Infectious; Pulmonary Embolism; Rifampin; Theophylline; Tuberculosis, Pulmonary	1985
Update on rifampin drug interactions. Archives of internal medicine, 1987, Volume: 147, Issue:3 Topics: Adrenergic beta-Antagonists; Cyclosporins; Digoxin; Drug Interactions; Humans; Ketoconazole; Phenytoin; Rifampin; Theophylline; Verapamil	1987
Adverse drug reactions checklist. British medical journal (Clinical research ed.), 1987, Feb-28, Volume: 294, Issue:6571 Topics: Female; Humans; Middle Aged; Rifampin; Theophylline	1987
Rifampicin-isoniazid and delayed elimination of theophylline: a case report. International journal of clinical pharmacology research, 1988, Volume: 8, Issue:4 Topics: Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Lung Diseases, Obstructive; Male; Middle Aged; Recurrence; Rifampin; Theophylline; Time Factors; Tuberculosis, Pulmonary	1988
[Interactions of theophylline with erythromycin, rifampicin and lincomycin]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Jun-27, Volume: 43, Issue:26 Topics: Adult; Bronchitis; Chronic Disease; Drug Interactions; Drug Therapy, Combination; Dyphylline; Erythromycin; Humans; Lincomycin; Male; Middle Aged; Rifampin; Theophylline	1988
Effect of rifampicin administration on theophylline pharmacokinetics in humans. The American review of respiratory disease, 1985, Volume: 131, Issue:6 Topics: Adult; Asthma; Drug Interactions; Humans; Kinetics; Lung Diseases, Obstructive; Male; Rifampin; Theophylline	1985
Ribonucleic acid and protein synthesis in rat heart mitochondria isolated after aortic constriction, strenuous physical exercise, total myocardial ischemia, and theophylline treatment. Recent advances in studies on cardiac structure and metabolism, 1973, Volume: 3 Topics: Animals; Cardiomegaly; Cell Nucleus; Cell-Free System; Chloramphenicol; Coronary Circulation; Cyclic AMP; DNA-Directed RNA Polymerases; Ischemia; Male; Mitochondria, Muscle; Muscle Proteins; Myocardium; Physical Exertion; Rats; Rifampin; RNA; Theophylline	1973
Theophylline-rifampicin interaction: non-selective induction of theophylline metabolic pathways. British journal of clinical pharmacology, 1984, Volume: 18, Issue:3 Topics: Adult; Biotransformation; Cytochrome P-450 Enzyme System; Dealkylation; Drug Interactions; Humans; Male; Oxidation-Reduction; Rifampin; Theophylline	1984
Effect of rifampin on theophylline disposition. Therapeutic drug monitoring, 1984, Volume: 6, Issue:2 Topics: Administration, Oral; Adult; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Rifampin; Theophylline	1984
Noneffect of rifampin on theophylline disposition in rabbits. Research communications in chemical pathology and pharmacology, 1982, Volume: 38, Issue:3 Topics: Animals; Kinetics; Male; Rabbits; Rifampin; Theophylline	1982
In vivo modulation of CYP enzymes by quinidine and rifampin. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:4 Topics: Acetylation; Administration, Oral; Adrenergic alpha-Antagonists; Adult; Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Enzyme Inhibitors; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Quinidine; Reference Values; Rifampin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline	2000
Chronological effects of rifampicin discontinuation on cytochrome P450 activity in healthy Japanese volunteers, using the cocktail method. Clinical pharmacology and therapeutics, 2013, Volume: 94, Issue:6 Topics: Adult; Antibiotics, Antitubercular; Asian People; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Imidazoles; Losartan; Male; Midazolam; Omeprazole; Rifampin; Tetrazoles; Theophylline; Time Factors; Withholding Treatment	2013