theophylline and quinidine

theophylline has been researched along with quinidine in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (40.86)	18.7374
1990's	16 (17.20)	18.2507
2000's	20 (21.51)	29.6817
2010's	19 (20.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aubé, J; Chu, YK; Chung, D; Golden, JE; Guo, H; Jonsson, CB; McKellip, S; Noah, JW; Rasmussen, L; Roy, S; Schroeder, CE; Smith, LH; Smith, RA; Sosa, M; Sotsky, J; Tower, NA; White, EL; Yao, T	1
Bajda, M; Brus, B; Czerwińska, P; Filipek, B; Gobec, S; Malawska, B; Sałat, K; Więckowska, A; Więckowski, K	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bienkowski, P; Bucki, A; Gobec, S; Godyń, J; Głuch-Lutwin, M; Kazek, G; Knez, D; Kołaczkowski, M; Malawska, B; Marcinkowska, M; Mierzejewski, P; Sienkiewicz-Jarosz, H; Siwek, A; Wichur, T; Więckowska, A; Więckowski, K; Zaręba, P	1
Farmer, JB; Farrar, DG	1
Scott, WA; Solomon, B	1
Bair, CH; Huang, JD	1
Matsuda, T; Mori, M; Tsushima, H	1
Burlina, A; Paleari, CD; Secchiero, S; Zaninotto, M	1
Bachmann, KA; Madhira, MS; Rankin, GO	1
Huddart, H; Lynch, M	1
Savage, AO; Unekwe, PC	1
Huang, JD	1
Lennard, MS; Loft, S; Otton, SV; Poulsen, HE; Tucker, GT	1
Bachmann, KA; Forney, RB; Jauregui, L; Martin, M; Nunlee, M; Schwartz, J	1
Bottorff, MB; Hunt, BA; Lalonde, RL; Self, TH	1
Bodmeier, R; Chen, HG	1
Jenkins, LC; Scoates, PJ	1
Dodd, NJ; Houslay, MD; Needham, L	1
Ceroni, G; Dorigo, P; Gaion, RM; Giacometti, A; Maragno, I; Valentini, E	1
Castellani, W; Chou, D; Galen, RS; Matzen, RN; Van Lente, F	1
Devine, JE	1
Caron, G; Sheehan, M	1
Suzuki, H	1
Atanga, GK; Savage, AO	1
Pitterle, ME; Sorkness, CA; Wiederholt, JB	1
Goodman, HM; Schimmel, RJ	1
Fain, JN; Pointer, RH	1
Bowman, WC; Hall, MT	1
Homola, D; Rotrekl, J; Srnová, V	1
Kośmider, S; Maślankiewicz, A; Tendera, M; Tuganowki, W	1
Praël, E; Strubelt, O	1
Huttman, DH	1
Martin, W	1
Ishikawa, Y; Takahashi, T; Yamamura, T	1
Horikoshi, I; Nishimura, Y; Takeguchi, N	1
Bauer, V; Kuriyama, H; Matusák, O	1
Kulkarni, SK; Mehta, AK	1
Klotz, U	1
DiGregorio, GJ; Fruncillo, RJ	1
Ojewole, JA	1
Ng, PK	1
Bonora, MR; Guaglio, R; Rondanelli, R; Terzoni, PA	1
Frierson, JL; Honig, CR	1
Busselen, P	1
Fernandez, IP; Herrera Carranza, J; Mac-Kay, MV; Sancez Burson, J	1
Bachmann, KA; Jauregui, L	1
Bayliss, MK; Eddershaw, PJ; Herriott, D; Manchee, GR; Park, GR; Ranshaw, LE; Tarbit, MH	1
Begnini, J; Bellot, RG; De-La-Vega, DD; Frussa-Filho, R; Jimenez-Bernal, RE; Lopes, FP; Mello, CF; Schwartz, CC	1
Jones, BC; Smith, DA; Tyman, CA	1
Akbaş, N; Barlas, A; Küçükhüseyin, C; Oncel, H; Payat, M; Silan, C	1
Hata, T; Iwasaki, K; Kaneko, H; Shiraga, T; Suzuki, A; Tozuka, Z	1
Adedoyin, A; Branch, RA; Frye, RF; Romkes, M; Wilson, JW	1
Airarat, W; Cha-on, U; Kukongviriyapan, U; Kukongviriyapan, V; Simajareuk, S	1
Beckurts, KT; Brachtendorf, L; Fuhr, U; Hölscher, AH; Jetter, A	1
Hyland, R; Jones, BC; Smith, DA	1
Chiba, K; Kobayashi, K; Shimada, N; Urashima, K	1
BRAVENY, P; HLAVKOVA STEJSKALOVA, J; HUSAKOVA, B; KRUTA, V	1
FOERSTER, K; KROETZ, C	1
Fouda, HG; Khojasteh-Bakht, SC; Prakash, C; Rossulek, MI	1
Gottesdiener, KM; Kari, PP; Marbury, T; Miller, JL; Mistry, GC; Rodrigues, AD; Simpson, RC; Wagner, JA; Winchell, GA	1
Fuhr, U; Kober, S; Mutschler, E; Spahn-Langguth, H; Zaigler, M	1
Capasso, A; Gallo, C	1
Erve, JC; Vashishtha, SC; Wu, G	1
Camenisch, G; Chibale, K; Huth, F; Njuguna, NM; Schiller, H; Umehara, KI	1
Brignole, M; Deharo, JC; Franceschi, F; Guieu, R; Hourdain, J; Koutbi, L; Perrin, T	1

Reviews

3 review(s) available for theophylline and quinidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Calcium channel blockers as inhibitors of drug metabolism. Chest, 1989, Volume: 96, Issue:2 Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Carbamazepine; Cyclosporins; Digitalis Glycosides; Drug Interactions; Humans; Liver; Prazosin; Quinidine; Theophylline	1989
Anaesthetic implications of calcium channel blockers. Canadian Anaesthetists' Society journal, 1985, Volume: 32, Issue:4 Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Asthma; Calcium; Calcium Channel Blockers; Dantrolene; Digoxin; Drug Interactions; Esophagus; Humans; Hyperkalemia; Intracranial Pressure; Malignant Hyperthermia; Neuromuscular Blocking Agents; Quinidine; Theophylline; Vasoconstriction	1985

Trials

3 trial(s) available for theophylline and quinidine

Article	Year
[Use of Coritrate in the prevention of paroxysmal tachycardia]. Vnitrni lekarstvi, 1973, Volume: 19, Issue:9 Topics: Adult; Aged; Ajmaline; Cardiac Glycosides; Clinical Trials as Topic; Drug Combinations; Female; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Procainamide; Quinidine; Tachycardia, Paroxysmal; Theophylline	1973
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid	1993
The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist. Journal of clinical pharmacology, 2005, Volume: 45, Issue:6 Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Area Under Curve; Carbon Radioisotopes; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fomepizole; Half-Life; Humans; Ketoconazole; Male; Microsomes, Liver; Pyrazoles; Pyrimidinones; Quinidine; Receptors, Adrenergic, alpha-1; Sulfaphenazole; Theophylline	2005

Other Studies

87 other study(ies) available for theophylline and quinidine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus. Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20 Topics: Animals; Antiviral Agents; Benzamides; Drug Evaluation, Preclinical; Encephalitis Virus, Venezuelan Equine; Encephalomyelitis, Venezuelan Equine; Heterocyclic Compounds, 2-Ring; Mice, Inbred C3H; Mice, Inbred C57BL; Piperazines; Quinazolinones; Small Molecule Libraries; Structure-Activity Relationship; Virus Replication	2014
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo. Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10 Topics: Acetylcholinesterase; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Humans; Indans; Indoles; Male; Memory; Mice; Models, Molecular; Neuroprotective Agents; Phthalimides; Piperidines; Protein Aggregates; Scopolamine; Structure-Activity Relationship	2015
Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT European journal of medicinal chemistry, 2016, Nov-29, Volume: 124 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Catalytic Domain; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Drug Design; Humans; Kinetics; Ligands; Male; Models, Molecular; Molecular Targeted Therapy; Protein Conformation; Rats; Rats, Wistar; Receptors, Serotonin	2016
Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle. The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:10 Topics: Adenine; Adenosine; Animals; Dipyridamole; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Propranolol; Quinidine; Theophylline; Trachea	1976
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations. Journal of bacteriology, 1975, Volume: 122, Issue:2 Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline	1975
Drugs in the elderly. The Medical letter on drugs and therapeutics, 1979, May-18, Volume: 21, Issue:10 Topics: Aged; Analgesics; Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diuretics; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypnotics and Sedatives; Male; Psychotropic Drugs; Quinidine; Theophylline	1979
Effect of theophylline on the intestinal clearance of drugs in rats. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:6 Topics: Algorithms; Animals; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Male; Models, Biological; Perfusion; Quinidine; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Theophylline; Urea	1992
Antidiuretic effects of purinoceptor agonists injected into the hypothalamic paraventricular nucleus of water-loaded, ethanol-anesthetized rats. Neuropharmacology, 1992, Volume: 31, Issue:6 Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diuresis; Ethanol; Male; Osmotic Pressure; Paraventricular Hypothalamic Nucleus; Quinidine; Rats; Rats, Wistar; Receptors, Purinergic; Stereotaxic Techniques; Theophylline; Time Factors	1992
Performance of a fluorescence polarization immunoassay system evaluated by therapeutic monitoring of four drugs. Therapeutic drug monitoring, 1992, Volume: 14, Issue:4 Topics: Amikacin; Calibration; Drug Monitoring; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Gentamicins; Humans; Pharmaceutical Preparations; Quinidine; Reference Standards; Theophylline	1992
The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances. Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:1 Topics: Animals; Antipyrine; Cobalt; Ethosuximide; Liver; Male; Mixed Function Oxygenases; Proadifen; Quinidine; Rats; Rats, Inbred Strains; Succinimides; Theophylline	1992
Purinergic modulation of field stimulation responses of rat and human vas deferens smooth muscle. General pharmacology, 1991, Volume: 22, Issue:5 Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Electric Stimulation; Guanethidine; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinidine; Rats; Receptors, Purinergic; Theophylline; Urinary Bladder; Vas Deferens; Vasodilator Agents	1991
The effects of electrical stimulation, adenosine and adenosine-5'-triphosphate (ATP) on mouse rectal muscle. Pharmacological research, 1991, Volume: 23, Issue:4 Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Dipyridamole; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Isotonic Solutions; Male; Mice; Muscle Contraction; Muscle, Smooth; Physostigmine; Potassium Chloride; Quinidine; Rectum; Temperature; Theophylline	1991
Role of unstirred water layer in the exsorption of quinidine. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:6 Topics: Animals; Chemical Phenomena; Chemistry, Physical; Diffusion; Intestinal Absorption; Male; Pectins; Perfusion; Quinidine; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Serum Albumin, Bovine; Theophylline; Thiopental	1990
Characterization of metronidazole metabolism by human liver microsomes. Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8 Topics: Acetone; Adult; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mephenytoin; Metronidazole; Microsomes, Liver; Middle Aged; Nifedipine; Phenacetin; Quinidine; Theophylline; Tolbutamide	1991
The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism. Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:5 Topics: Antipyrine; Carbamazepine; Glucuronosyltransferase; Humans; Liver; Lorazepam; Male; Metabolic Clearance Rate; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Polycyclic Compounds; Quinidine; Smoking; Theophylline; Valproic Acid	1990
Evaluation of biodegradable poly(lactide) pellets prepared by direct compression. Journal of pharmaceutical sciences, 1989, Volume: 78, Issue:10 Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Compounding; Microscopy, Electron, Scanning; Molecular Weight; Polyesters; Propranolol; Quinidine; Solubility; Spectrophotometry, Infrared; Theophylline; Viscosity	1989
Quinidine and melittin both decrease the fluidity of liver plasma membranes and both inhibit hormone-stimulated adenylate cyclase activity. Biochimica et biophysica acta, 1987, May-12, Volume: 899, Issue:1 Topics: Adenylyl Cyclases; Animals; Bee Venoms; Cell Membrane; Electron Spin Resonance Spectroscopy; Kinetics; Liver; Male; Melitten; Membrane Fluidity; Quinidine; Rats; Rats, Inbred Strains; Theophylline; Thermodynamics	1987
The response of isolated guinea-pig aorta to amrinone. Journal of autonomic pharmacology, 1988, Volume: 8, Issue:1 Topics: Adenosine; Adenosine Deaminase; Amrinone; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Quinidine; Theophylline	1988
Application of the EXPERT consultation system to accelerated laboratory testing and interpretation. Clinical chemistry, 1986, Volume: 32, Issue:9 Topics: Adolescent; Adult; Aged; Artificial Intelligence; Bilirubin; Blood Glucose; Chemistry Techniques, Analytical; Diagnosis, Computer-Assisted; Digoxin; Female; Gilbert Disease; Hemoglobins; Hemolysis; Humans; Laboratories; Liver; Male; Middle Aged; Quinidine; Theophylline; Thyroxine	1986
Assessment of the Corvac blood collection tube for drug specimen processing. Therapeutic drug monitoring, 1986, Volume: 8, Issue:2 Topics: Blood Specimen Collection; Humans; Lidocaine; Pentobarbital; Pharmaceutical Preparations; Phenytoin; Quinidine; Theophylline; Time Factors	1986
Evaluation of an automated system (Optimate) for substrate-labeled fluorescent immunoassays. Therapeutic drug monitoring, 1985, Volume: 7, Issue:1 Topics: Anti-Bacterial Agents; Carbamazepine; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Indicators and Reagents; Methods; Phenobarbital; Phenytoin; Primidone; Quinidine; Theophylline	1985
Electrical responses of smooth muscle cells of the rabbit ear artery to adenosine triphosphate. The Journal of physiology, 1985, Volume: 359 Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cocaine; Dose-Response Relationship, Drug; Ear, External; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Phentolamine; Quinidine; Rabbits; Theophylline	1985
Effect of adenosine 5'triphosphate (ATP) on the isolated rectum of the rainbow lizard Agama agama. General pharmacology, 1985, Volume: 16, Issue:3 Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Chloride; Carbachol; Dipyridamole; In Vitro Techniques; Lizards; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Potassium Chloride; Quinidine; Rectum; Theophylline	1985
Use of serum drug concentrations in outpatient clinics. American journal of hospital pharmacy, 1985, Volume: 42, Issue:7 Topics: Carbamazepine; Digoxin; Humans; Medication Systems, Hospital; Outpatient Clinics, Hospital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Quinidine; Theophylline; Wisconsin	1985
Release of pre-formed free fatty acids from adipose tissue: acceleration by cyclic AMP. Endocrinology, 1972, Volume: 90, Issue:5 Topics: Adipose Tissue; Animals; Butyrates; Culture Media; Cyclic AMP; Depression, Chemical; Drug Synergism; Epididymis; Epinephrine; Fatty Acids, Nonesterified; Hypophysectomy; In Vitro Techniques; Insulin; Male; Pituitary Gland; Quinacrine; Quinidine; Rats; Stimulation, Chemical; Theophylline	1972
Response of isolated white fat cells to anti-malarial drugs. Biochemical pharmacology, 1973, Dec-01, Volume: 22, Issue:23 Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Antimalarials; Bucladesine; Chloroquine; Drug Synergism; Fatty Acids, Nonesterified; Female; Glycerol; Norepinephrine; Primaquine; Proteins; Quinacrine; Quinidine; Rats; Theophylline; Triglycerides	1973
Inhibition of rabbit intestine mediated by alpha- and beta-adrenoceptors. British journal of pharmacology, 1970, Volume: 38, Issue:2 Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cyclic AMP; Epinephrine; Female; Imidazoles; Intestines; Isoproterenol; Male; Phenylephrine; Quinidine; Rabbits; Receptors, Drug; Sympathomimetics; Theophylline	1970
The effect of quinidine bis-(7-theophyline acetate) on the isolated papillary muscle of the rabbit heart. Experientia, 1973, Sep-15, Volume: 29, Issue:9 Topics: Action Potentials; Animals; Drug Combinations; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscles; Papillary Muscles; Quinidine; Rabbits; Theophylline	1973
[Pharmacological effects on the contraction frequency of isolated rat portal vein]. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 198, Issue:2 Topics: Aconitum; Animals; Atropine; Caffeine; Carbachol; Epinephrine; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Nitrites; Norepinephrine; Papaverine; Peptides; Phentolamine; Portal Vein; Propranolol; Quinidine; Rats; Rats, Inbred Strains; Reserpine; Strophanthins; Theophylline; Tyramine	1972
[Aspirin in the treatment of myocardial infarct]. Giornale di clinica medica, 1971, Volume: 52, Issue:10 Topics: Aspirin; Bicarbonates; Blood Coagulation; Blood Sedimentation; Gastrointestinal Diseases; Hematuria; Heparin; Humans; Myocardial Infarction; Papaverine; Phenobarbital; Quinidine; Theophylline	1971
[Therapy of heart diseases]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968, Apr-01, Volume: 88, Issue:7 Topics: Digitalis Glycosides; Electroconvulsive Therapy; Heart Diseases; Oxygen Inhalation Therapy; Pacemaker, Artificial; Quinidine; Sympatholytics; Theophylline	1968
[Intoxication with Coritrat (an anti-arrhythmia combination drug)]. Munchener medizinische Wochenschrift (1950), 1969, Feb-21, Volume: 111, Issue:8 Topics: Adult; Anti-Arrhythmia Agents; Barbiturates; Electrocardiography; Heart; Humans; Hypokalemia; Kidney; Male; Meprobamate; Methods; Pancreas; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Suicide; Theophylline	1969
[Action of adenosine 5'-triphosphate and effects of various purinergic receptor blocking agents on the movements of an isolated guinea pig gallbladder]. Nihon Heikatsukin Gakkai zasshi, 1983, Volume: 19, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Apamin; Atropine; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phentolamine; Propranolol; Quinidine; Receptors, Cell Surface; Receptors, Purinergic; Tetrodotoxin; Theophylline	1983
Ca2+ removal effects on bullfrog gastric mucosa in the presence of drugs. The Japanese journal of physiology, 1980, Volume: 30, Issue:6 Topics: Animals; Bucladesine; Calcimycin; Calcium; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Potassium; Quinidine; Rana catesbeiana; Theophylline	1980
Non-cholinergic, non-adrenergic responses to nerve stimulation of different regions of the guinea-pig small intestine. Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 319, Issue:2 Topics: Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Intestine, Small; Male; Membrane Potentials; Muscle Contraction; Norepinephrine; Quinidine; Synaptic Transmission; Theophylline	1982
Evidence for the presence of P1- and P2-purinoceptors in rat caecum. Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 264, Issue:2 Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Cecum; Cyclic AMP; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline	1983
Performance of a new automated substrate-labeled fluorescence immunoassay system evaluated by comparative therapeutic monitoring of five drugs. Therapeutic drug monitoring, 1984, Volume: 6, Issue:3 Topics: Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Stability; Fluorescent Antibody Technique; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Spectrometry, Fluorescence; Theophylline	1984
Pharmacokinetics of pentobarbital, quinidine, lidocaine, and theophylline in the thermally injured rat. Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:8 Topics: Animals; Burns; Dialysis; Kinetics; Lidocaine; Male; Pentobarbital; Quinidine; Rats; Rats, Inbred Strains; Theophylline	1984
Non-cholinergic, non-adrenergic responses of the rainbow lizard isolated rectum to transmural electrical stimulation. Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:7 Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Female; In Vitro Techniques; Lizards; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Parasympathetic Nervous System; Quinidine; Rectum; Sympathetic Nervous System; Theophylline	1983
Phenytoin-theophylline-quinidine interaction. The New England journal of medicine, 1983, 03-24, Volume: 308, Issue:12 Topics: Adult; Aged; Drug Interactions; Female; Humans; Male; Middle Aged; Phenytoin; Quinidine; Theophylline	1983
Prediction of multiple-dose blood level curves of drugs administered four times daily at non-uniform dosing intervals. International journal of bio-medical computing, 1981, Volume: 12, Issue:3 Topics: Absorption; Administration, Oral; Child; Computers; Drug Administration Schedule; Humans; Models, Biological; Pharmaceutical Preparations; Quinidine; Tetracycline; Theophylline	1981
Clinical pharmacokinetics: the pharmacological monitoring of plasmatic levels in therapy. International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:2 Topics: Digoxin; Drug Administration Schedule; Gentamicins; Humans; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Salicylates; Theophylline	1980
Role of adenosine in exercise vasodilation in dog gracilis muscle. The American journal of physiology, 1980, Volume: 238, Issue:5 Topics: Adenosine; Animals; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Muscle Contraction; Muscles; Quinidine; Theophylline; Vasodilation	1980
Effects of caffeine and other substances on sodium- and calcium-independent efflux in cyanide poisoned goldfish ventricles. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:2 Topics: Animals; Biological Transport, Active; Caffeine; Calcium; Cyanides; Goldfish; In Vitro Techniques; Myocardium; Naphazoline; Quinidine; Sarcoplasmic Reticulum; Theophylline	1980
An in vitro study of the influence of a drug's molecular weight on its overall (Clt), diffusive (Cld) and convective (Clc) clearance through dialysers. Biopharmaceutics & drug disposition, 1995, Volume: 16, Issue:1 Topics: Convection; Diffusion; Digoxin; Kinetics; Models, Chemical; Molecular Weight; Pharmaceutical Preparations; Quinidine; Renal Dialysis; Theophylline; Tobramycin; Vancomycin	1995
The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:5 Topics: Adrenergic beta-Agonists; Albuterol; Biomarkers; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfiram; Humans; Isoenzymes; Ketoconazole; Microsomes, Liver; Midazolam; Molecular Structure; Oxidation-Reduction; Quinidine; Recombinant Proteins; Salmeterol Xinafoate; Sulfaphenazole; Theophylline	1996
Antinociceptive effect of purine nucleotides. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1996, Volume: 29, Issue:10 Topics: Analgesics; Animals; Caffeine; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Purine Nucleotides; Quinidine; Receptors, Purinergic P1; Receptors, Purinergic P2; Rosaniline Dyes; Suramin; Theophylline	1996
Identification of the cytochrome P450 isoforms involved in the O-demethylation of 4-nitroanisole in human liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:10 Topics: Adult; Aged; Anisoles; Anti-Infective Agents; Anticoagulants; Antifungal Agents; Antimalarials; Binding, Competitive; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Kinetics; Male; Methylation; Microsomes, Liver; Middle Aged; Quinidine; Substrate Specificity; Sulfaphenazole; Theophylline	1997
On the mechanisms of adenosine induced pulmonary vasoconstriction in rats. Journal of basic and clinical physiology and pharmacology, 1997, Volume: 8, Issue:4 Topics: Adenosine; Adrenergic Antagonists; Animals; Cyclooxygenase Inhibitors; Cyproheptadine; Dihydroergotoxine; Endothelium, Vascular; Female; Flavonoids; Ginkgo biloba; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Plant Extracts; Platelet Activating Factor; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Quinidine; Rats; Rats, Sprague-Dawley; Theophylline; Vasoconstriction	1997
Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3 Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dibenzothiepins; Enzyme Inhibitors; Humans; Immune Sera; Isoenzymes; Ketoconazole; Microsomes, Liver; Oxidation-Reduction; Quinidine; Recombinant Proteins; Theophylline	1999
In vivo modulation of CYP enzymes by quinidine and rifampin. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:4 Topics: Acetylation; Administration, Oral; Adrenergic alpha-Antagonists; Adult; Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Enzyme Inhibitors; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Quinidine; Reference Values; Rifampin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline	2000
Alteration of drug kinetics in rats following exposure to trichloroethylene. Pharmacology, 2001, Volume: 63, Issue:2 Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Hypnotics and Sedatives; Male; Pentobarbital; Pharmacokinetics; Phosphodiesterase Inhibitors; Quinidine; Rats; Rats, Sprague-Dawley; Sex Factors; Solvents; Theophylline; Trichloroethylene	2001
Cytochrome P450 enzymes contributing to demethylation of maprotiline in man. Pharmacology & toxicology, 2002, Volume: 90, Issue:3 Topics: Cells, Cultured; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzymes; Humans; Ketoconazole; Kinetics; Maprotiline; Mephenytoin; Microsomes, Liver; Models, Biological; Quinidine; Sulfaphenazole; Theophylline	2002
Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:5 Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Oxidation-Reduction; Pyrimidines; Quinidine; Sulfaphenazole; Theophylline; Triazoles; Voriconazole	2003
Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:7 Topics: Aniline Compounds; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; DNA, Complementary; Enzyme Inhibitors; Gene Expression; Humans; Isoenzymes; Ketoconazole; Methoxsalen; Microsomes, Liver; Quinidine; Rats; Steroid 16-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Sulfaphenazole; Theophylline	2003
[RESTORATION OF MYOCARDIAL CONTRACTILITY AND INOTROPIC EFFECTS (OUABAIN, QUINIDINE, TYRAMINE, THEOPHYLLINE AND ACETYLCHOLINE) IN GUINEA PIGS AND RATS]. Scripta medica, 1963, Volume: 36 Topics: Acetylcholine; Guinea Pigs; Muscle Contraction; Myocardium; Ouabain; Quinidine; Rats; Research; Strophanthins; Theophylline; Tyramine	1963
[ANTI-ARRHYTHMIC SUBSTANCES IN THE TREATMENT OF THE HEART]. Medizinische Klinik, 1965, Apr-09, Volume: 60 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Drug Therapy; Heart; Humans; Meprobamate; Phenobarbital; Procainamide; Quinidine; Rauwolfia; Tachycardia; Tachycardia, Paroxysmal; Theophylline; Ventricular Fibrillation	1965
Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543. Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:12 Topics: Adolescent; Adult; Aged; Chromans; Coumarins; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Ketoconazole; Kinetics; Male; Mephenytoin; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Quinidine; Receptors, Leukotriene B4; Recombinant Proteins; Sulfaphenazole; Theophylline	2003
Rate-limiting biotransformation of triamterene is mediated by CYP1A2. International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:7 Topics: Caffeine; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Humans; Hydroxylation; Ketoconazole; Kinetics; Microsomes, Liver; Omeprazole; Quinidine; Substrate Specificity; Sulfuric Acid Esters; Theophylline; Triamterene	2005
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence. Current drug safety, 2009, Volume: 4, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline	2009
Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs. Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8 Topics: Animals; Binding Sites; Cytosol; Drug Design; Duloxetine Hydrochloride; Glutathione; Glutathione Transferase; Humans; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Quinidine; Rationalization; Rats; Structure-Activity Relationship; Theophylline; Thiophenes	2010
Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction. Drug metabolism and personalized therapy, 2016, 12-01, Volume: 31, Issue:4 Topics: Acetates; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Phenotype; Quinidine; Quinolines; Sulfaphenazole; Sulfides; Theophylline; Ticlopidine	2016
Theophylline as an adjunct to control malignant ventricular arrhythmia associated with early repolarization. Pacing and clinical electrophysiology : PACE, 2018, Volume: 41, Issue:5 Topics: Anti-Arrhythmia Agents; Child; Defibrillators, Implantable; Disopyramide; Humans; Male; Quinidine; Recurrence; Tachycardia, Ventricular; Theophylline; Vasodilator Agents	2018