theophylline and quercetin

theophylline has been researched along with quercetin in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199014 (50.00)18.7374
1990's2 (7.14)18.2507
2000's4 (14.29)29.6817
2010's6 (21.43)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Al-Nadaf, AH; Al-Sha'er, MA; Khanfar, MA; Taha, MO1
Corvaisier, S; Cresteil, T; Dallemagne, P; El Kihel, L; Jourdan, JP; Lecoutey, C; Legay, R; Malzert-Fréon, A; Rochais, C; Since, M; Sopkova-de Oliveira Santos, J1
Andrisano, V; Apperley, KYP; Bartolini, M; Baschieri, A; Basso, M; Chen, HH; De Simone, A; Guardigni, M; Keillor, JW; Kobrlova, T; Milelli, A; Montanari, S; Soukup, O; Valgimigli, L1
Cheng, M; Fang, Y; Guo, J; Jin, Y; Liu, J; Wan, Y; Wang, R; Xie, SS; Zhang, Z; Zhou, W1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Chayoth, R; Graziani, Y; Winikoff, J1
Lazarus, SC; Osborne, ML; Sommerhoff, CP1
Barrett, KE; Metcalfe, DD1
Barrett, KE; Metcalfe, DD; Szucs, EF1
Fox, CC; Kagey-Sobotka, A; Lichtenstein, LM; Wolf, EJ1
Brahmi, Z; Steele, TA1
De Sousa, RC; Grosso, A1
Atkinson, G; Ennis, M; Pearce, FL1
Ennis, M; Pearce, FL; Truneh, A; White, JR1
Kurose, M; Saeki, K1
Drzewiecki, G; Krishnarao, D; Middleton, E1
Pearce, FL; Truneh, A2
Kurose, M1
Pearce, FL; White, JR1
Dănilă, G; Olinescu, R; Păduraru, I; Petrariu, D; Saramet, A1
Chadwick, LR; Guo, J; Nikolic, D; Pauli, GF; van Breemen, RB1
Alexander, SP1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Other Studies

28 other study(ies) available for theophylline and quercetin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Algorithms; Dose-Response Relationship, Drug; Drug Discovery; Humans; Ligands; Models, Molecular; Molecular Structure; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship

2014
Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment.
    European journal of medicinal chemistry, 2016, May-23, Volume: 114

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzyl Compounds; Cell Proliferation; Dose-Response Relationship, Drug; Humans; KB Cells; Models, Molecular; Molecular Structure; Protein Aggregates; Protein Binding; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured

2016
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Oct-20, Volume: 139

    Topics: Alzheimer Disease; Animals; Cinnamates; Dose-Response Relationship, Drug; Free Radical Scavengers; Glycogen Synthase Kinase 3 beta; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

2017
Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzothiazoles; Benzylamines; Biphenyl Compounds; Butyrylcholinesterase; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Electrophorus; Horses; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neuroprotective Agents; Picrates; Rats; Structure-Activity Relationship; Sulfonic Acids; Xanthones

2021
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
Regulation of cyclic AMP level and lactic acid production in Ehrlich ascites tumor cells.
    Biochimica et biophysica acta, 1977, Apr-27, Volume: 497, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cyclic AMP; Kinetics; Lactates; Male; Mice; Mice, Inbred ICR; Prostaglandins E; Quercetin; Theophylline

1977
Effect of inhibitors on histamine release from mast cells recovered by bronchoalveolar lavage in basenji-greyhound and mongrel dogs.
    Agents and actions, 1990, Volume: 31, Issue:3-4

    Topics: Animals; Bronchoalveolar Lavage Fluid; Calcimycin; Cromolyn Sodium; Dogs; Histamine Release; Mast Cells; Nedocromil; Quercetin; Quinolones; Theophylline

1990
The histologic and functional characterization of enzymatically dispersed intestinal mast cells of nonhuman primates: effects of secretagogues and anti-allergic drugs on histamine secretion.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:3

    Topics: Animals; Calcimycin; Cell Separation; Cells, Cultured; Cromolyn Sodium; Haplorhini; Histamine Release; Immunoglobulin E; Intestine, Small; Lasalocid; Mast Cells; p-Methoxy-N-methylphenethylamine; Quercetin; Theophylline

1985
Mast cell heterogeneity in higher animals: a comparison of the properties of autologous lung and intestinal mast cells from nonhuman primates.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Sep-15, Volume: 137, Issue:6

    Topics: Animals; Bucladesine; Haplorhini; Histamine Release; Immunoglobulin E; Intestines; Isoproterenol; Lung; Mast Cells; Quercetin; SRS-A; Staining and Labeling; Substance P; Theophylline

1986
Comparison of human lung and intestinal mast cells.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Cells, Cultured; Cromolyn Sodium; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Intestinal Mucosa; Lung; Mast Cells; Quercetin; Rats; Theophylline; Thioxanthenes; Xanthones

1988
Phosphatidylinositol metabolism accompanies early activation events in tumor target cell-stimulated human natural killer cells.
    Cellular immunology, 1988, Apr-01, Volume: 112, Issue:2

    Topics: Adult; Bucladesine; Calcium; Cell Line; Cytotoxicity, Immunologic; Extracellular Space; Humans; Killer Cells, Natural; Kinetics; Leukemia, Erythroblastic, Acute; Lymphocyte Activation; Phosphatidylinositols; Quercetin; Theophylline

1988
Forskolin mimics the hydrosmotic action of vasopressin in the urinary bladder of toads Bufo marinus.
    The Journal of physiology, 1985, Volume: 365

    Topics: Animals; Bufo marinus; Colforsin; Cyclic AMP; Diamide; Diterpenes; In Vitro Techniques; Methohexital; Osmosis; Quercetin; Theophylline; Urinary Bladder; Vasopressins; Water

1985
Inhibition of histamine release induced by compound 48/80 and peptide 401 in the presence and absence of calcium. Implications for the mode of action of anti-allergic compounds.
    Agents and actions, 1980, Volume: 10, Issue:3

    Topics: Animals; Bee Venoms; Bucladesine; Calcium; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Glycolysis; Histamine Antagonists; Histamine Release; Hypersensitivity; Male; p-Methoxy-N-methylphenethylamine; Peptides; Quercetin; Rats; Theophylline

1980
Inhibition of histamine secretion from mast cells.
    Nature, 1981, Jan-15, Volume: 289, Issue:5794

    Topics: Animals; Antigens; Calcimycin; Calcium; Cells, Cultured; Cromolyn Sodium; Cyclic AMP; Histamine Release; Mast Cells; Quercetin; Rats; Theophylline

1981
Histamine release from rat mast cells sensitized with mouse antiserum.
    Agents and actions, 1981, Volume: 11, Issue:1-2

    Topics: Animals; Antibodies; Calcium; Cromolyn Sodium; Histamine Release; Immunoglobulin E; Male; Mast Cells; Mice; Quercetin; Rats; Theophylline

1981
Quercetin: an inhibitor of antigen-induced human basophil histamine release.
    Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 127, Issue:2

    Topics: Antigens; Basophils; Buffers; Calcium; Cyclic AMP; Deuterium; Flavonoids; Histamine Release; Humans; Leukocytes; Quercetin; Rutin; Theophylline; Time Factors

1981
Effect of anti-allergic compounds on histamine release from rat peritoneal mast cells treated with concanavalin A.
    International archives of allergy and applied immunology, 1981, Volume: 66, Issue:1

    Topics: Animals; Bucladesine; Concanavalin A; Cromolyn Sodium; Dose-Response Relationship, Drug; Edetic Acid; Histamine Release; Mast Cells; Phosphatidylserines; Quercetin; Rats; Tetrazoles; Theophylline; Thioxanthenes; Xanthones

1981
Inhibition of anaphylactic histamine release from heterologously sensitized mast cells: differential effects of drugs which interfere with calcium influx.
    Acta medica Okayama, 1981, Volume: 35, Issue:5

    Topics: Animals; Antigens; Biological Transport; Calcium; Cromolyn Sodium; Histamine Release; Immunization; Immunoglobulin E; Male; Mast Cells; Mice; Mice, Inbred BALB C; Quercetin; Rats; Rats, Inbred Strains; Theophylline; Verapamil

1981
Effect of anti-allergic compounds on anaphylactic histamine secretion from rat peritoneal mast cells in the presence and absence of exogenous calcium.
    Immunology, 1982, Volume: 46, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Anaphylaxis; Animals; Ascitic Fluid; Bronchodilator Agents; Calcium; Cromolyn Sodium; Cyclic AMP; Dose-Response Relationship, Drug; Female; Histamine Release; Male; Mast Cells; Quercetin; Rats; Rats, Inbred Strains; Theophylline; Thioxanthenes; Xanthones

1982
Effect of cyclic AMP, disodium cromoglycate and other anti-allergic drugs on histamine secretion from rat mast cells stimulated with the calcium ionophore ionomycin.
    Agents and actions, 1984, Volume: 14, Issue:2

    Topics: Animals; Bronchodilator Agents; Calcium; Cromolyn Sodium; Cyclic AMP; Ethers; Female; Histamine H1 Antagonists; Histamine Release; Ionomycin; Ionophores; Kinetics; Male; Mast Cells; Quercetin; Rats; Rats, Inbred Strains; Theophylline; Thioxanthenes; Xanthones

1984
Direct detection of the antioxidant activity of a new flavonic derivative using the chemiluminescence method.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:5

    Topics: Antioxidants; Drug Combinations; Free Radicals; Hydrogen Peroxide; Kinetics; Luminescent Measurements; Oxidation-Reduction; Quercetin; Rutin; Solutions; Spectrophotometry, Infrared; Theophylline

1996
Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.).
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Dealkylation; Enzyme Inhibitors; Flavanones; Humans; Humulus; Hydroxylation; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quercetin; Theophylline; Xanthones

2006
Flavonoids as antagonists at A1 adenosine receptors.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:11

    Topics: Adenosine A1 Receptor Antagonists; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Conductivity; Female; Flavonoids; Guinea Pigs; Ileum; Male; Muscle Contraction; Quercetin; Radioligand Assay; Receptor, Adenosine A1; Theophylline; Xanthines

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007