theophylline has been researched along with propylthiouracil in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (40.74) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Robison, GA; Thompson, WJ; Van Inwegen, RG | 1 |
| Barney, CC; Field, FP; Fregly, MJ; Katovich, MJ | 1 |
| Dasler, R; Fregly, MJ; Lutherer, LO; Tyler, PE | 1 |
| Varrone, S; Wolff, J | 1 |
| Desbarats-Schönbaum, ML; Koves, E; Laansoo, M; Schönbaum, E; Sellers, EA | 1 |
| Vaughan, M | 1 |
| Bastomsky, CH; McKenzie, JM; Zakarija, M | 2 |
| Armstrong, KJ; Robison, GA; Stouffer, JE; Thompson, WJ; Van Inwegen, RG | 1 |
| Granner, DK; Halmi, NS | 1 |
| Imura, H; Inada, M; Ishii, H; Kuma, K; Mashio, Y; Matsuzuka, F; Naito, K; Nishikawa, M; Tanaka, K | 1 |
| Koibuchi, N; Ma, HT; Matsuzaki, S; Reuse, S | 1 |
| Sitar, DS | 1 |
| Gharaibeh, SF; Jaradat, A; Obeidat, WM | 1 |
1 review(s) available for theophylline and propylthiouracil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
26 other study(ies) available for theophylline and propylthiouracil
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Cyclic nucleotide phosphodiesterases and thyroid hormones.
Topics: Adipose Tissue; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Epinephrine; Glycerol; Hypothyroidism; Kinetics; Lipid Mobilization; Male; Phosphoric Diester Hydrolases; Propylthiouracil; Protein Kinases; Rats; Theophylline; Thyroid Gland; Thyroid Hormones; Time Factors; Triiodothyronine; Xanthines | 1975 |
Catecholamine-thyroid hormone interaction in cold-acclimated rats.
Topics: Acclimatization; Animals; Blood Pressure; Body Temperature; Body Temperature Regulation; Catecholamines; Cold Temperature; Female; Heart Rate; Isoproterenol; Propranolol; Propylthiouracil; Rats; Skin Temperature; Theophylline; Thyroid Hormones | 1979 |
Reversal by theophylline of some changes characteristically accompanying hypothyroidism in rats.
Topics: Amitrole; Animals; Blood Pressure; Body Weight; Diet; Drug Evaluation, Preclinical; Growth; Heart Rate; Hypothyroidism; Iodine; Male; Oxygen Consumption; Propylthiouracil; Rats; Theophylline; Thyroid Gland | 1978 |
The methyl xanthines--a new class of goitrogens.
Topics: Aminophylline; Animals; Antithyroid Agents; Blood Proteins; Caffeine; Cyclic AMP; Drug Synergism; Goiter; Hypophysectomy; In Vitro Techniques; Iodine; Male; Propylthiouracil; Protein Binding; Rats; Theobromine; Theophylline; Thyroid Gland | 1969 |
Effects of low concentrations of thyroid stimulating hormone: pharmacological experiments in vitro.
Topics: Animals; Drug Synergism; Guinea Pigs; Iodides; Iodine Isotopes; Ouabain; Potassium; Propylthiouracil; Theophylline; Thyroid Function Tests; Thyroid Gland; Thyrotropin | 1970 |
An in vitro effect of triiodothyronine on rat adipose tissue.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cycloheximide; Epinephrine; Fatty Acids; Glucagon; Glucose; Glycerides; In Vitro Techniques; Propylthiouracil; Rats; Theophylline; Thyrotropin; Triiodothyronine | 1967 |
Thyroid hydrolysis of cyclic AMP as influenced by thyroid gland activity.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Cyclic AMP; Depression, Chemical; Diet; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Iodine; Kinetics; Male; Nucleotidases; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Propylthiouracil; Rats; Stimulation, Chemical; Theophylline; Thyroid Gland; Thyroid Hormones; Thyrotropin; Tritium | 1971 |
Stimulation of the adenyl cyclase-cyclic AMP system in the thyroid of the rat.
Topics: Adenylyl Cyclases; Animals; Carbon Isotopes; Cyclic AMP; Diet; In Vitro Techniques; Iodine; Male; Phosphorus Isotopes; Propylthiouracil; Prostaglandins; Radioimmunoassay; Rats; Theophylline; Thyroid Gland; Thyroid Hormones; Thyrotropin; Tritium | 1973 |
Effects of thyroid hormone deficiency on cyclic adenosine 3':5'-monophosphate and control of lipolysis in fat cells.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Bucladesine; Cell Membrane; Centrifugation, Density Gradient; Cyclic AMP; Epinephrine; Glucagon; Hypothyroidism; Lipid Metabolism; Lipid Mobilization; Male; Phosphoric Diester Hydrolases; Propylthiouracil; Rats; Theophylline; Triiodothyronine; Tritium | 1974 |
Lack of positive correlation between adenyl cyclase activity and iodide transport in rat thyroids.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Hypophysectomy; Iodides; Iodine Isotopes; Male; Organ Size; Phosphorus Isotopes; Pituitary Gland; Propylthiouracil; Rats; Theophylline; Thyroid Gland; Thyrotropin; Tritium | 1972 |
Induction of outer and inner ring monodeiodinases in human thyroid gland by thyrotropin.
Topics: Bucladesine; Culture Techniques; Dactinomycin; Enzyme Induction; Graves Disease; Humans; Iodide Peroxidase; Kinetics; Peroxidases; Propylthiouracil; Theophylline; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1983 |
Acute inhibitory effect of excess iodide on ornithine decarboxylase in the thyroid of propylthiouracil-treated rats.
Topics: Animals; Blotting, Northern; Bucladesine; Depression, Chemical; Hypothyroidism; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Potassium Iodide; Propylthiouracil; Rats; Rats, Wistar; RNA, Messenger; Theophylline; Thyroid Gland | 1996 |
Old drugs - old people - new insights.
Topics: Aging; Humans; Morphine; Pharmaceutical Preparations; Pharmacology, Clinical; Propylthiouracil; Theophylline | 2005 |
The Influence of Drugs Solubilities and Chitosan-TPP Formulation Parameters on the Mean Hydrodynamic Diameters and Drugs Entrapment Efficiencies into Chitosan-TPP Nanoparticles.
Topics: Antipyrine; Ascorbic Acid; Chitosan; Drug Carriers; Hydrodynamics; Nanoparticles; Particle Size; Polymers; Propylthiouracil; Solubility; Theophylline | 2022 |