theophylline has been researched along with prazosin in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (30.23) | 18.7374 |
| 1990's | 11 (25.58) | 18.2507 |
| 2000's | 11 (25.58) | 29.6817 |
| 2010's | 8 (18.60) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H; Takashima, S | 1 |
| Reid, A; Sawynok, J | 1 |
| Goldie, RG; Paterson, JW; Rigby, PJ; Spina, D | 1 |
| Majewski, H; Murphy, TV | 1 |
| Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Bottorff, MB; Hunt, BA; Lalonde, RL; Self, TH | 1 |
| Gotoh, K; Hori, M; Iwai, K; Iwakura, K; Kagiya, T; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J | 1 |
| Connolly, E; Nedergaard, J | 1 |
| Kantoh, M; Kusunoki, M; Takahashi, T; Utsunomiya, J; Yamamura, T | 1 |
| Muramatsu, I | 1 |
| Advenier, C; Boukef, K; Fehri, B | 1 |
| Galloway, MP; Reinhard, JF; Roth, RH | 1 |
| Curtis-Prior, PB; Tan, S | 1 |
| Berlan, M; Carpene, C; Dang-Tran, L; Lafontan, M | 1 |
| Chujo, M; Hori, M; Inoue, M; Kitakaze, M; Minamino, T; Mori, H; Morioka, T; Node, K; Shinozaki, Y; Takeda, H | 1 |
| Bohmann, C; Rump, LC; Schaible, U; von Kügelgen, I | 1 |
| Athari, A; Hänecke, K; Jungermann, K | 1 |
| el-Sawalhi, MM; Ismail, NA; Megahed, YM; Shaheen, AA | 1 |
| Hashimoto, T; Ishii, R; Kunitomo, M; Shinozuka, K; Takeuchi, K | 1 |
| Chien, GL; Davis, RF; Haessler, R; Kuzume, K; Van Winkle, DM; Wolff, RA | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| Camacho, SA; Diamond, I; Figueredo, VM; Miyamae, M; Zhou, HZ | 1 |
| Chiba, S; Yang, XP | 1 |
| Awan, MM; Forresti, S; Makaula, S; Opie, LH; Sack, MN | 1 |
| Georgiev, VP; Pechlivanova, DM | 1 |
3 review(s) available for theophylline and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Calcium channel blockers as inhibitors of drug metabolism.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Carbamazepine; Cyclosporins; Digitalis Glycosides; Drug Interactions; Humans; Liver; Prazosin; Quinidine; Theophylline | 1989 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
40 other study(ies) available for theophylline and prazosin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Endogenous adenosine blunts beta-adrenoceptor-mediated inotropic response in hypoperfused canine myocardium.
Topics: Adenosine; Animals; Coronary Disease; Dogs; Heart; Isoproterenol; Myocardial Contraction; Prazosin; Receptors, Adrenergic, beta; Theophylline | 1992 |
Noradrenergic and purinergic involvement in spinal antinociception by 5-hydroxytryptamine and 2-methyl-5-hydroxytryptamine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Oxidopamine; Pain; Phentolamine; Prazosin; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Purinergic; Serotonin; Spinal Cord; Theophylline; Yohimbine | 1991 |
Alpha 1-adrenoceptor function and autoradiographic distribution in human asthmatic lung.
Topics: Adult; Asthma; Autoradiography; Bronchi; Carbachol; Humans; In Vitro Techniques; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Lung; Male; Middle Aged; Muscle Relaxation; Muscle Tonus; Phenylephrine; Pindolol; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Theophylline | 1989 |
Modulation of noradrenaline release in slices of rat kidney cortex through alpha 1- and alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Indomethacin; Kidney Cortex; Male; Methoxamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Theophylline | 1989 |
Comparison between sympathetic adrenergic and purinergic transmission in the dog mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Cocaine; Dogs; Female; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Theophylline | 1989 |
Adenosine-induced hyperemia attenuates myocardial ischemia in coronary microembolization in dogs.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Embolism; Microspheres; Myocardium; Prazosin; Theophylline; Vasodilation | 1989 |
Beta-adrenergic modulation of Ca2+ uptake by isolated brown adipocytes. Possible involvement of mitochondria.
Topics: Adipose Tissue, Brown; Animals; Biological Transport, Active; Calcium; Colforsin; Cricetinae; Cyclic AMP; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Mesocricetus; Mitochondria; Norepinephrine; Palmitic Acids; Prazosin; Receptors, Adrenergic, beta; Theophylline | 1988 |
Different innervation mechanisms between the lesser and greater curvature of guinea pig antrum.
Topics: Animals; Apamin; Atropine; Chymotrypsin; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phentolamine; Prazosin; Propranolol; Pyloric Antrum; Tetrodotoxin; Theophylline; Vasoactive Intestinal Peptide; Yohimbine | 1989 |
The effect of reserpine on sympathetic, purinergic neurotransmission in the isolated mesenteric artery of the dog: a pharmacological study.
Topics: Adenosine Diphosphate; Animals; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Mesenteric Arteries; Neuropeptides; Potassium Chloride; Prazosin; Receptors, Purinergic; Reserpine; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Tyramine | 1987 |
[Effect of alpha and beta-blockaders on the anti-inflammatory effects of adrenaline and an adrenaline and theophylline combination].
Topics: Animals; Carrageenan; Drug Combinations; Drug Therapy, Combination; Edema; Epinephrine; Female; Isoproterenol; Male; Prazosin; Propranolol; Rats; Theophylline | 1988 |
Noradrenergic modulation of serotonin synthesis and metabolism. II. Stimulation by 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Serotonin; Theophylline; Tryptophan | 1983 |
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine | 1984 |
Alpha-2 adrenergic antilipolytic effect in dog fat cells: incidence of obesity and adipose tissue localization.
Topics: Adipose Tissue; Animals; Clonidine; Dogs; Epinephrine; Isoproterenol; Lipolysis; Obesity; Prazosin; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Yohimbine | 1982 |
Bidirectional effects of aminophylline on myocardial ischemia.
Topics: Adenosine; Aminophylline; Animals; Coronary Circulation; Dogs; Heart; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Prazosin; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P1; Reproducibility of Results; Theophylline | 1995 |
Alpha-adrenoceptor modulation of norepinephrine and ATP release in isolated kidneys of spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Hypertension; Kidney; Norepinephrine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Suramin; Tetrodotoxin; Theophylline; Yohimbine | 1995 |
Prostaglandin F2 alpha and D2 release from primary Ito cell cultures after stimulation with noradrenaline and ATP but not adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Dinoprost; Endothelium; Kupffer Cells; Liver; Male; Norepinephrine; Prazosin; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Stimulation, Chemical; Theophylline | 1994 |
Combined effect of adenosine, alpha adrenergic and adenosine antagonists on serum insulin and insulin secretion from rat pancreatic islets.
Topics: Adenosine; Animals; Drug Interactions; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Prazosin; Rats; Rats, Wistar; Theophylline; Xanthines; Yohimbine | 1994 |
Effect of 8-sulfophenyl theophylline on endogenous noradrenaline release from sympathetic nerves of the rabbit ear artery.
Topics: Animals; Arteries; Ear; Electric Stimulation; Norepinephrine; Peripheral Nerves; Prazosin; Purinergic P1 Receptor Antagonists; Rabbits; Sympathetic Nervous System; Theophylline | 1996 |
Adrenergic activation confers cardioprotection mediated by adenosine, but is not required for ischemic preconditioning.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Norepinephrine; Phentolamine; Prazosin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Tyramine | 1996 |
Alcohol consumption reduces ischemia-reperfusion injury by species-specific signaling in guinea pigs and rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Blood Pressure; Coronary Circulation; Creatine Kinase; Diastole; Guinea Pigs; Heart; Ischemic Preconditioning; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Prazosin; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reference Values; Signal Transduction; Species Specificity; Theophylline; Ventricular Function, Left | 1998 |
Adrenergic-purinergic interactions on vasoconstrictor responses to periarterial electric nerve stimulation in canine splenic arteries.
Topics: Adenosine Triphosphate; Animals; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nervous System Physiological Phenomena; Perfusion; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Splenic Artery; Sympatholytics; Theophylline; Yohimbine | 1999 |
Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Anti-Arrhythmia Agents; Benzophenanthridines; Caprylates; Decanoic Acids; Deoxyglucose; Enzyme Inhibitors; Glucose; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardium; Phenanthridines; Prazosin; Propranolol; Rats; Rats, Long-Evans; Signal Transduction; Theophylline | 2000 |
Effects of single and long-term theophylline treatment on the threshold of mechanical nociception: contribution of adenosine A1 and alpha2-adrenoceptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analgesics; Animals; Male; Pain Measurement; Pain Threshold; Prazosin; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline | 2005 |