theophylline and pentoxifylline

theophylline has been researched along with pentoxifylline in 88 studies

Research

Studies (88)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (29.55)	18.7374
1990's	28 (31.82)	18.2507
2000's	18 (20.45)	29.6817
2010's	11 (12.50)	24.3611
2020's	5 (5.68)	2.80

Authors

Authors	Studies
Hasegawa, T; Iwasaki, N; Konno, K; Kurita, M; Miyamoto, K; Ohshima, T; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y	1
Topliss, JG; Yoshida, F	1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Andersen, OA; Demartino, JA; Rao, FV; van Aalten, DM; Vora, KA	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Gwizdek-Wiśniewska, A; Piosik, J; Ulanowska, K; Wegrzyn, G	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Gołuński, G; Iermak, I; Piosik, J; Rychłowski, M; Woziwodzka, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Bucki, A; Chłoń-Rzepa, G; Gawalska, A; Jankowska, A; Kołaczkowski, M; Pawłowski, M; Pociecha, K; Ślusarczyk, M; Świerczek, A; Wyska, E	1
Cardinali, DP	1
Cartheuser, C; Komarek, J	1
Boksay, I; Csanyi, V; Gervai, J; Lajtha, A	1
Bang, YJ; Danielpour, D; Kim, KY; Kim, SJ; Myers, CE; O'Reilly, MA; Trepel, JB	1
Gottehrer, A; Vaughan, LM	1
Blaskó, G; Hermecz, I; Kapui, Z; Sarkadi, B; Szentmiklósi, P; Tardos, L	1
McCall, JL; Parry, BR; Tuckey, JA	1
Bardenheuer, H; Madel, C; Peter, K; Pöch, G; Thiel, M	1
Schmid-Schönbein, GW; Wong, PM	1
Mitsumoto, Y; Mohri, T; Ohkubo, T	1
Goto, M; Hayashi, S; Sakurai, M; Tanaka, Y	1
Cummings, DM; Ellison, MJ; Horner, RD; Willis, SE	1
Kunkel, SL; Larrick, J; Lynch, JP; Remick, DG; Spengler, RN; Strieter, RM; Ward, PA	1
Lupal'tsev, VI	1
El'skaia, IE; Neugodov, IuV; Popov, VV; Sokolov, GF	1
Sasaki, T; Tomita, K; Tsuchiya, H	1
Morton, MR; Parish, RC; Spruill, WJ	1
Freyburger, G; Hammerschmidt, DE; Huh, PW; Kotasek, D; McCarthy, T; Vercellotti, GM	1
Cohen, IA; Converse-Swastek, K; Johnson, CE; Wesolowicz, L	1
Gómez Reyes, D; Rojas Hidalgo, E	2
Grossmann, K; Knischka, A	1
Luke, DR; Rocci, ML; Saccar, CL	1
Pivovarova, EIa; Samsonov, AA; Vorob'ev, LP	1
Belinskaia, TF; Li, ED; Makoeva, LD; Margarian, AG; Sabaev, VV	1
Cummings, DM; Green, P; Rocci, ML; Saccar, C	1
Nuzov, BG	1
Aparicio, M; Basabe, JC; Cresto, JC; Fabiano de Bruno, L; Karabatas, L	1
Herman, G; Mauduit, P; Rossignol, B	1
Argel, MI; Chiappe, GE; Chiappe, LE; Cingolani, HE; Grassi, AO; Vittone, L	1
Bourguet, J; Favard, P	1
Beyreder, J	1
Benignetti, G; Benvenuti, C; Fabbri, F	1
Kasabian, IN; Kukes, VG; Mamaeva, GG; Spesivtseva, VG	1
Himberg, JJ; Johnsson, R	1
Hirota, S; Iwazaki, A; Miyagishima, A; Nozawa, Y; Sadzuka, Y	1
Moriuchi, H; Yuizono, T	1
Chapman, MG; Forman, RG; Gearon, CM; Guglielmino, A; Lanzafame, F	1
Hatake, K; Hishida, S; Marukawa, S; Wakabayashi, I	1
Beleta, J; Bou, J; Cardelús, I; Cortijo, J; Gristwood, RW; Llenas, J; Morcillo, E	1
Alléra, A; Eisenhut, T; Endres, S; Gebert, U; Moeller, J; Schönharting, MM; Semmler, J	1
Baudet, S; Binet, JL; Mentz, F; Merle-Béral, H; Ouaaz, F	1
Langermans, JA; Seijmonsbergen, EM; van der Meide, PH; van Furth, AM; van Furth, R	1
Binet, JL; Leblond, V; Mentz, F; Merle-Beral, H	1
Barancík, M; Breier, A; Stefanková, Z	1
Akaike, N; Kawa, K; Uneyama, H	1
Koren, R; Liberman, UA; Ravid, A; Saati, N	1
Aparicio, M; Cambar, J; Potier, M	1
Braune, J; Ebert, U; Grossmann, M; Kirch, W	1
Bitter-Suermann, S; Burdon, D; Entzian, P; Ernst, M; Schlaak, M; Zabel, P	1
Buratti, T; Dunzendorfer, S; Herold, M; Kähler, CM; Reinisch, N; Schratzberger, P; Tilg, H; Wiedermann, CJ	1
Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M	1
Daly, JW; Shi, D	1
Freichel, OL; Lippold, BC	1
Baba, A; Enomoto, R; Lee, E; Matsuda, T; Mori, K; Takuma, K	1
Boobis, AR; Edwards, RJ; Murray, BP; Murray, S; Odupitan, AO	1
Ghofrani, HA; Grimminger, F; Leuchte, H; Roehl, A; Schermuly, RT; Seeger, W; Walmrath, D; Weissmann, N	1
Savage, N; Uboldi, AD	1
Czyz, A; Gwizdek-Wiśniewska, A; Ochociński, J; Piosik, J; Ulanowska, K; Wegrzyn, G	1
Finocchiaro, S; Levine, RA; Nandi, J; Ong, G; Saud, B	1
Ulanowska, K; Wegrzyn, G	1
Anderson, CM; Thwaites, DT	1
Balwinski, KM; Mitchell, SA	1
Gwizdek-Wiśniewska, A; Piosik, J; Woziwodzka, A	1
Cohen, JD; Gallegos, AC; Lau, SS; Mastrandrea, NJ; Monks, TJ; Tham, KY	1
Brooks, MB; Divers, TJ; Hernandez, D; Ness, SL; Stokol, T; Yeo, WM	1
Byrne, PG; Keogh, LM; Silla, AJ	1
Bronskill, SE; Cheng, Y; Kalia, LV; Lacoste, AMB; Maclagan, LC; Marras, C; Tadrous, M; Visanji, NP	1
Bachmann, CM; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA; Seyfried, M	1
DuMontier, SP; Ganapathiraju, I; Kable, TJ; Mohr, JD; Sabates, BL; Smith, HL; Trump, MW; Wall, GC	1
Chen, DD; Le Grange, JM; Zhang, JN; Zheng, XF; Zhou, LQ; Zhu, XL	1
Bachmann, CM; Griebsch, LV; Grimm, HS; Grimm, MOW; Hartmann, T; Janitschke, D; Lauer, AA; Pilz, SM; Theiss, EL; Winkler, J	1

Reviews

4 review(s) available for theophylline and pentoxifylline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effect of xanthine-related compounds on a theophylline assay using theophylline oxidase. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:12 Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Oxidoreductases; Oxypurinol; Pentoxifylline; Theophylline; Xanthines	1992
Methylxanthines in surgery: a bright future? The Australian and New Zealand journal of surgery, 1992, Volume: 62, Issue:4 Topics: Humans; Neoplasms; Pentoxifylline; Respiratory Distress Syndrome; Shock, Septic; Surgical Procedures, Operative; Theophylline; Xanthines	1992
Pharmacological stimulation of sperm motility. Human reproduction (Oxford, England), 1994, Volume: 9, Issue:2 Topics: Caffeine; Deoxyadenosines; Humans; Infertility, Male; Male; Pentoxifylline; Relaxin; Sperm Motility; Theophylline	1994

Trials

6 trial(s) available for theophylline and pentoxifylline

Article	Year
Influence of pentoxifylline on steady-state theophylline serum concentrations from sustained-release formulations. Pharmacotherapy, 1990, Volume: 10, Issue:6 Topics: Adolescent; Adult; Delayed-Action Preparations; Drug Interactions; Female; Humans; Male; Middle Aged; Pentoxifylline; Theophylline	1990
[Teonicol and trental in the treatment of duodenal ulcer]. Sovetskaia meditsina, 1986, Issue:10 Topics: Adolescent; Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Duodenal Ulcer; Humans; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate	1986
Use of pentoxifylline in the treatment of acute cerebrovascular insufficiency. European neurology, 1983, Volume: 22 Suppl 1 Topics: Acute Disease; Benzamides; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hexobendine; Humans; Male; Pentoxifylline; Retrospective Studies; Theobromine; Theophylline	1983
[Use of trental and complamine in the microcirculatory disorders of diabetes mellitus]. Sovetskaia meditsina, 1980, Issue:2 Topics: Adult; Aged; Blood; Clinical Trials as Topic; Diabetic Angiopathies; Diabetic Nephropathies; Female; Humans; Hypoglycemic Agents; Male; Microcirculation; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate	1980
Dilatory effects of phosphodiesterase inhibitors on human hand veins in vivo. European journal of clinical pharmacology, 1998, Volume: 54, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Amrinone; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enoximone; Female; Hand; Humans; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Vasodilation; Vasodilator Agents; Veins	1998
Effects of various antiplatelet drugs on ex vivo platelet activation induced by equine herpesvirus type 1. American journal of veterinary research, 2016, Volume: 77, Issue:12 Topics: Animals; Aspirin; Clopidogrel; Cross-Over Studies; Double-Blind Method; Female; Flow Cytometry; Herpesviridae Infections; Herpesvirus 1, Equid; Horse Diseases; Horses; Male; Pentoxifylline; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Theophylline; Ticlopidine	2016

Other Studies

78 other study(ies) available for theophylline and pentoxifylline

Article	Year
Bronchodilator activity of xanthine derivatives substituted with functional groups at the 1- or 7-position. Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10 Topics: Administration, Oral; Animals; Bronchial Spasm; Bronchodilator Agents; Guinea Pigs; Heart Rate; Male; Mice; Muscle Relaxation; Structure-Activity Relationship; Trachea; Xanthines	1993
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11 Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes. Chemistry & biology, 2005, Volume: 12, Issue:9 Topics: Chitinases; Enzyme Inhibitors; Models, Molecular; Molecular Structure; Protein Binding; Xanthines	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Impaired mutagenic activities of MPDP(+) (1-methyl-4-phenyl-2,3-dihydropyridinium) and MPP(+) (1-methyl-4-phenylpyridinium) due to their interactions with methylxanthines. Bioorganic & medicinal chemistry, 2007, Aug-01, Volume: 15, Issue:15 Topics: 1-Methyl-4-phenylpyridinium; Caffeine; Calorimetry; Drug Interactions; Models, Molecular; Molecular Structure; Mutagens; Pentoxifylline; Pyridinium Compounds; Spectrophotometry, Atomic; Vibrio	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Modulation of acridine mutagen ICR191 intercalation to DNA by methylxanthines--analysis with mathematical models. Bioorganic & medicinal chemistry, 2013, Jun-01, Volume: 21, Issue:11 Topics: Aminacrine; Animals; Caffeine; Cattle; DNA; Drug Antagonism; Epithelial Cells; Intercalating Agents; Kidney; Kinetics; Models, Chemical; Mutagens; Nitrogen Mustard Compounds; Pentoxifylline; Salmonella typhimurium; Theophylline; Thermodynamics	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Novel butanehydrazide derivatives of purine-2,6-dione as dual PDE4/7 inhibitors with potential anti-inflammatory activity: Design, synthesis and biological evaluation. European journal of medicinal chemistry, 2018, Feb-25, Volume: 146 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanes; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 7; Dose-Response Relationship, Drug; Drug Design; Endotoxemia; Humans; Hydrazines; Lipopolysaccharides; Male; Molecular Structure; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Structure-Activity Relationship	2018
Effects of pentoxifylline and theophylline on neurotransmitter uptake and release by synaptosome-rich homogenates of the rat hypothalamus. Neuropharmacology, 1977, Volume: 16, Issue:11 Topics: Animals; Bucladesine; Dopamine; Glutamates; Hypothalamus; Male; Neurotransmitter Agents; Norepinephrine; Pentoxifylline; Potassium; Rats; Serotonin; Synaptosomes; Theobromine; Theophylline; Xanthines	1977
[Effect of pentoxifylline, xanthinol nicotinate and theophylline on the cardiovascular system, myocardial dynamics and left ventricular contractility of the dog in short-system, experiments]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:10 Topics: Animals; Dogs; Hemodynamics; Myocardial Contraction; Myocardium; Oxygen Consumption; Pentoxifylline; Theobromine; Theophylline; Time Factors; Xanthinol Niacinate	1977
The influence of methylxanthines on precursor incorporation into protein and RNA of mouse brain. Brain research, 1976, Nov-26, Volume: 117, Issue:2 Topics: Aminophylline; Animals; Animals, Newborn; Brain; Cycloheximide; Isoleucine; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Penicillins; Pentoxifylline; RNA; Streptomycin; Theophylline; Time Factors; Uridine; Xanthines	1976
Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3. Proceedings of the National Academy of Sciences of the United States of America, 1992, Apr-15, Volume: 89, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; Aprotinin; Blotting, Northern; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leupeptins; Male; Pentoxifylline; Phenylmethylsulfonyl Fluoride; Prostatic Neoplasms; RNA, Neoplasm; Theophylline; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured	1992
Comparative studies of drotaverine--acephyllinate (Depogen) and pentoxifylline (Trental). Thrombosis research, 1992, Jun-15, Volume: 66, Issue:6 Topics: Animals; Cell Aggregation; Drug Combinations; Drug Evaluation, Preclinical; Erythrocytes; Humans; Leukocytes; Papaverine; Pentoxifylline; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Factor 3; Rabbits; Theophylline	1992
Pentoxifylline does not act via adenosine receptors in the inhibition of the superoxide anion production of human polymorphonuclear leukocytes. Biochemical and biophysical research communications, 1991, Oct-15, Volume: 180, Issue:1 Topics: Adenosine; Dose-Response Relationship, Drug; Drug Combinations; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Purinergic Antagonists; Receptors, Purinergic; Superoxides; Theophylline	1991
Attenuation of spontaneous pseudopod formation in human neutrophils by pentoxifylline. Cell biophysics, 1991, Volume: 18, Issue:3 Topics: Actins; Adult; Complement C5a; Cytoplasm; Dose-Response Relationship, Drug; Endotoxins; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pseudopodia; Receptors, Purinergic; Theophylline; Time Factors	1991
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives. Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2 Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines	1991
Effect of xanthine derivatives on hippocampal long-term potentiation. Brain research, 1990, Jul-02, Volume: 522, Issue:1 Topics: Animals; Cyclic AMP; Electrodes; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Pentoxifylline; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline; Xanthines	1990
Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline. Biochemical and biophysical research communications, 1988, Sep-30, Volume: 155, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Assay; Bucladesine; Cyclic AMP; Dinoprostone; Lipopolysaccharides; Mice; Pentoxifylline; Theobromine; Theophylline; Tumor Necrosis Factor-alpha	1988
[Use of a combination of rheopolyglucin, complamin and trental in the complex treatment of acute postoperative pancreatitis]. Klinicheskaia khirurgiia, 1988, Issue:11 Topics: Acute Disease; Dextrans; Drug Therapy, Combination; Humans; Pancreatitis; Pentoxifylline; Platelet Aggregation Inhibitors; Postoperative Complications; Theobromine; Theophylline; Xanthinol Niacinate	1988
[The onset of circulatory venous gangrene of the arm and its successful treatment by thrombolysis]. Vestnik khirurgii imeni I. I. Grekova, 1989, Volume: 143, Issue:11 Topics: Adult; Arm; Drug Therapy, Combination; Female; Fibrinolytic Agents; Gangrene; Heparin; Humans; Infusions, Intravenous; Pentoxifylline; Subclavian Vein; Theobromine; Theophylline; Thrombolytic Therapy; Thrombosis; Xanthinol Niacinate	1989
[DNA repair and drug resistance: enhancement of the effects of anticancer agents by DNA repair inhibitors]. Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:3 Pt 2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Caffeine; Cell Division; Child; Cisplatin; DNA Repair; Doxorubicin; Drug Resistance; Drug Synergism; Humans; Male; Middle Aged; Osteosarcoma; Pentoxifylline; Theophylline; Tumor Cells, Cultured	1989
Lack of theophylline assay interference from pentoxifylline and its metabolites. Therapeutic drug monitoring, 1989, Volume: 11, Issue:3 Topics: Aged; Fluorescence Polarization; Humans; Pentoxifylline; Theobromine; Theophylline	1989
Pentoxifylline inhibits granulocyte and platelet function, including granulocyte priming by platelet activating factor. The Journal of laboratory and clinical medicine, 1988, Volume: 112, Issue:2 Topics: Blood Platelets; Cell Adhesion; Cell Aggregation; Chemotaxis, Leukocyte; Endothelium, Vascular; Granulocytes; Humans; Pentoxifylline; Platelet Activating Factor; Platelet Adhesiveness; Platelet Aggregation; Superoxides; Theobromine; Theophylline; Thrombin	1988
Effect of pentoxifylline and its metabolites on three theophylline assays. Clinical pharmacy, 1988, Volume: 7, Issue:6 Topics: Adult; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Male; Pentoxifylline; Theobromine; Theophylline	1988
[Therapeutic results with xanthine derivatives in the intermittent claudication syndrome in diabetic patients]. Revista clinica espanola, 1988, Volume: 182, Issue:1 Topics: Adult; Aged; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Intermittent Claudication; Male; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate	1988
[Intra-arterial therapy of arterial occlusive diseases of the extremities]. Zeitschrift fur arztliche Fortbildung, 1987, Volume: 81, Issue:17 Topics: Actihaemyl; Adenosine Triphosphate; Anti-Bacterial Agents; Arterial Occlusive Diseases; Drug Therapy, Combination; Female; Humans; Infusion Pumps; Infusions, Intra-Arterial; Ischemia; Leg; Male; Middle Aged; Nicotinyl Alcohol; Pentoxifylline; Theophylline; Tissue Extracts	1987
Pharmacokinetics of pentoxifylline during concomitant theophylline administration to rats. Pharmaceutical research, 1987, Volume: 4, Issue:5 Topics: Animals; Drug Interactions; Male; Pentoxifylline; Rats; Rats, Inbred Strains; Theobromine; Theophylline	1987
[Xanthinic derivatives in the treatment of intermittent claudication syndrome in diabetic patients]. Revista clinica espanola, 1986, Volume: 179, Issue:3 Topics: Diabetes Complications; Diabetic Angiopathies; Drug Therapy, Combination; Humans; Intermittent Claudication; Pentoxifylline; Theophylline; Xanthinol Niacinate	1986
[Effect of beta-adrenergic blockaders and trental on plasma levels of renin and aldosterone in healthy persons during antiorthostatic hypokinesia]. Kardiologiia, 1985, Volume: 25, Issue:6 Topics: Adult; Aldosterone; Humans; Immobilization; Male; Pentoxifylline; Posture; Propranolol; Renin; Theobromine; Theophylline; Time Factors	1985
Interference potential of pentoxifylline and its major metabolite with theophylline assays. American journal of hospital pharmacy, 1985, Volume: 42, Issue:12 Topics: Biotransformation; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Pentoxifylline; Theobromine; Theophylline	1985
[Use of teonikol and trental in the combined treatment of patients with suppurative surgical infection and concomitant diabetes mellitus]. Klinicheskaia meditsina, 1985, Volume: 63, Issue:12 Topics: Chronic Disease; Conjunctiva; Diabetes Mellitus; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Pentoxifylline; Plethysmography, Impedance; Surgical Wound Infection; Theobromine; Theophylline; Time Factors; Xanthinol Niacinate	1985
A comparative study of two insulin secretion inhibitors: somatostatin and diazoxide. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1982, Volume: 14, Issue:7 Topics: Animals; Arginine; Calcimycin; Diazoxide; Glucose; Imidazoles; Insulin; Insulin Antagonists; Insulin Secretion; Male; Pentoxifylline; Rats; Rats, Inbred Strains; Somatostatin; Theophylline; Tubulin	1982
A tentative explanation of the stimulatory effect of methylxanthines (pentoxifylline and isobutylmethylxanthine) on the secretory process in rat extraorbital lacrimal gland. Scandinavian journal of clinical and laboratory investigation. Supplementum, 1981, Volume: 156 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Lacrimal Apparatus; Male; Norepinephrine; Pentoxifylline; Proteins; Rats; Rats, Inbred Strains; Sympathomimetics; Theobromine; Theophylline; Xanthines	1981
Effect of phosphodiesterase inhibitors on heart contractile behaviour, protein kinase activity and cyclic nucleotide levels. Journal of molecular and cellular cardiology, 1980, Volume: 12, Issue:10 Topics: Animals; Cyclic AMP; Cyclic GMP; Myocardial Contraction; Myocardium; Nucleotides, Cyclic; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Theophylline	1980
Effects of pentoxifylline and various methylxanthine derivatives on transepithelial water permeability of frog urinary bladder. Scandinavian journal of clinical and laboratory investigation. Supplementum, 1981, Volume: 156 Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Epithelium; Osmosis; Pentoxifylline; Permeability; Rana esculenta; Theobromine; Theophylline; Urinary Bladder; Vasopressins; Water; Xanthines	1981
[Therapeutic efficacy of pentoxifylline in peripheral artery diseases: its clinical value]. La Clinica terapeutica, 1983, Feb-28, Volume: 104, Issue:4 Topics: Aged; Arterial Occlusive Diseases; Blood Viscosity; Female; Humans; Male; Middle Aged; Pentoxifylline; Theobromine; Theophylline; Xanthinol Niacinate	1983
Thrombocyte aggregation in hereditary spherocytosis. Clinica chimica acta; international journal of clinical chemistry, 1982, Mar-12, Volume: 119, Issue:3 Topics: Adenosine Diphosphate; Adult; Chromium Radioisotopes; Collagen; Epinephrine; Female; Humans; Male; Middle Aged; Pentoxifylline; Platelet Aggregation; Ristocetin; Spherocytosis, Hereditary; Splenectomy; Theophylline	1982
Effects of methylxanthine derivatives on adriamycin concentration and antitumor activity. Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:6 Topics: Animals; Caffeine; Carcinoma, Ehrlich Tumor; Doxorubicin; Drug Synergism; Male; Mice; Pentoxifylline; Theobromine; Theophylline	1995
Pentoxifylline prevents a decrease in arterial oxygen tension in oleic acid-induced lung injury. Critical care medicine, 1995, Volume: 23, Issue:2 Topics: Airway Resistance; Animals; Blood Pressure; Capillary Permeability; Carbon Dioxide; Guinea Pigs; Hydrogen-Ion Concentration; Hypoxia; Oleic Acid; Oleic Acids; Oxygen; Pentoxifylline; Prospective Studies; Pulmonary Circulation; Respiratory Distress Syndrome; Theophylline	1995
Vasorelaxant effects of oxpentifylline and theophylline on rat isolated aorta. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:5 Topics: Animals; Aorta, Thoracic; Arginine; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Pentoxifylline; Rats; Rats, Wistar; Theophylline; Vasodilator Agents	1994
Investigation into the role of phosphodiesterase IV in bronchorelaxation, including studies with human bronchus. British journal of pharmacology, 1993, Volume: 108, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aged; Animals; Asthma; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoenzymes; Isoproterenol; Male; Middle Aged; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Theophylline; Xanthines	1993
Xanthine derivatives: comparison between suppression of tumour necrosis factor-alpha production and inhibition of cAMP phosphodiesterase activity. Immunology, 1993, Volume: 78, Issue:4 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Pentoxifylline; Theophylline; Tumor Necrosis Factor-alpha; Xanthines	1993
[In vitro induction of apoptosis in chronic lymphoid leukemia B lymphocytes by theophylline: therapeutic applications]. Bulletin de l'Academie nationale de medecine, 1995, Volume: 179, Issue:7 Topics: Aged; Antineoplastic Agents, Alkylating; Apoptosis; Asthma; B-Lymphocytes; Bronchodilator Agents; Chlorambucil; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Pentoxifylline; Remission Induction; Theophylline; Time Factors; Tumor Cells, Cultured; Vasodilator Agents	1995
Effect of xanthine derivates and dexamethasone on Streptococcus pneumoniae-stimulated production of tumor necrosis factor alpha, interleukin-1 beta (IL-1 beta), and IL-10 by human leukocytes. Clinical and diagnostic laboratory immunology, 1995, Volume: 2, Issue:6 Topics: Caffeine; Cytokines; Dexamethasone; Glucocorticoids; Humans; Interleukin-1; Interleukin-10; Leukocytes; Pentoxifylline; Streptococcus pneumoniae; Theophylline; Tumor Necrosis Factor-alpha; Xanthines	1995
Synergistic action of alkylating agents and methylxanthine derivatives in the treatment of chronic lymphocytic leukemia. Leukemia, 1995, Volume: 9, Issue:12 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Xanthines	1995
Overcoming of P-glycoprotein mediated vincristine resistance of L1210/VCR mouse leukemic cells could be induced by pentoxifyline but not by theophylline and caffeine. Neoplasma, 1996, Volume: 43, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Calcium; Calcium Channels; Drug Interactions; Drug Resistance, Neoplasm; Leukemia L1210; Mice; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha; Vincristine	1996
Inhibitory effect of methylxanthines on glycine-induced Cl current in dissociated rat hippocampal neurons. Annals of the New York Academy of Sciences, 1993, Dec-20, Volume: 707 Topics: Animals; Caffeine; Chloride Channels; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Pentoxifylline; Pyramidal Cells; Rats; Rats, Wistar; Theobromine; Theophylline; Xanthines	1993
1,25-dihydroxyvitamin D3 and agents that increase intracellular adenosine 3',5'-monophosphate synergistically inhibit fibroblast proliferation. In vitro cellular & developmental biology. Animal, 1997, Volume: 33, Issue:4 Topics: 24,25-Dihydroxyvitamin D 3; 3',5'-Cyclic-AMP Phosphodiesterases; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Mice; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline	1997
Protective effect of three xanthine derivatives (theophylline, caffeine and pentoxifylline) against the cyclosporin A-induced glomerular contraction in isolated glomeruli and cultured mesangial cells. Nephron, 1997, Volume: 77, Issue:4 Topics: Animals; Caffeine; Cells, Cultured; Cyclosporine; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Immunosuppressive Agents; In Vitro Techniques; Kidney Glomerulus; Male; Muscle Contraction; Pentoxifylline; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines	1997
Differences in the anti-inflammatory effects of theophylline and pentoxifylline: important for the development of asthma therapy? Allergy, 1998, Volume: 53, Issue:8 Topics: Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Blood Cells; Cells, Cultured; Female; Humans; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Male; Middle Aged; Pentoxifylline; Phytohemagglutinins; Reactive Oxygen Species; Theophylline; Tumor Necrosis Factor-alpha; Xanthines	1998
Mediator-dependent effects of pentoxifylline on endothelium for transmigration of neutrophils. Immunopharmacology, 1999, Volume: 41, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adjuvants, Immunologic; Bucladesine; Cell Adhesion; Cell Movement; Endothelium, Vascular; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-1; Interleukin-8; Lipopolysaccharides; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha	1999
Effects of phosphodiesterase inhibitors on cytokine production by microglia. Multiple sclerosis (Houndmills, Basingstoke, England), 1999, Volume: 5, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines	1999
Chronic effects of xanthines on levels of central receptors in mice. Cellular and molecular neurobiology, 1999, Volume: 19, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain Chemistry; Caffeine; Calcium Channels; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Drug Interactions; Gene Expression Regulation; Male; Mice; Nerve Tissue Proteins; Pentoxifylline; Radioligand Assay; Receptors, Cholinergic; Receptors, Drug; Receptors, GABA; Receptors, Purinergic P1; Receptors, Serotonin; Theobromine; Theophylline; Xanthines	1999
A new oral erosion controlled drug delivery system with a late burst in the release profile. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 50, Issue:3 Topics: Administration, Oral; Carboxylic Acids; Colloids; Delayed-Action Preparations; Drug Delivery Systems; Excipients; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Pentoxifylline; Polyvinyl Alcohol; Solubility; Tablets; Theophylline	2000
Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model. British journal of pharmacology, 2001, Volume: 133, Issue:6 Topics: Alkaloids; Animals; Animals, Newborn; Apoptosis; Astrocytes; Carbazoles; Cell Survival; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytochrome c Group; Dipyridamole; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Indoles; Mitochondria; Pentoxifylline; Peptide Hydrolases; Phosphodiesterase Inhibitors; Purinones; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Theophylline; Vinca Alkaloids	2001
Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline. Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:3 Topics: Acetaminophen; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Caffeine; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inhibitory Concentration 50; Kinetics; Magnesium Chloride; Microsomes, Liver; Mixed Function Oxygenases; Models, Chemical; Pentoxifylline; Phenacetin; Protein Binding; Serum Albumin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline; Time Factors; Tromethamine; Xanthines	2001
Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Antihypertensive Agents; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epoprostenol; Hypertension, Pulmonary; Nebulizers and Vaporizers; Pentoxifylline; Phosphodiesterase Inhibitors; Pressure; Pulmonary Gas Exchange; Rabbits; Theophylline; Vasoconstrictor Agents; Ventilation-Perfusion Ratio	2001
The adenylate cyclase activator forskolin partially protects L929 cells against tumour necrosis factor-alpha-mediated cytotoxicity via a cAMP-independent mechanism. Cytokine, 2002, Sep-07, Volume: 19, Issue:5 Topics: Adenylyl Cyclases; Cell Death; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cyclosporine; DNA Fragmentation; Humans; Pentoxifylline; Theophylline; Time Factors; Tumor Necrosis Factor-alpha	2002
Methylxanthines (caffeine, pentoxifylline and theophylline) decrease the mutagenic effect of daunomycin, doxorubicin and mitoxantrone. Acta biochimica Polonica, 2005, Volume: 52, Issue:4 Topics: Antimutagenic Agents; Caffeine; Cell Survival; Daunorubicin; Doxorubicin; Mitoxantrone; Mutagenicity Tests; Pentoxifylline; Structure-Activity Relationship; Theophylline; Vibrio; Xanthenes	2005
Inhibition of TNF-alpha improves indomethacin-induced enteropathy in rats by modulating iNOS expression. Digestive diseases and sciences, 2005, Volume: 50, Issue:9 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Down-Regulation; Ileitis; Indomethacin; Inflammation; Jejunal Diseases; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Theophylline; Tumor Necrosis Factor-alpha; Up-Regulation	2005
Mutagenic activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Journal of applied genetics, 2006, Volume: 47, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aminoacridines; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Caffeine; Central Nervous System Stimulants; Doxorubicin; Free Radical Scavengers; Mutagenicity Tests; Neurotoxins; Nitrogen Mustard Compounds; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Vibrio	2006
Regulation of intestinal hPepT1 (SLC15A1) activity by phosphodiesterase inhibitors is via inhibition of NHE3 (SLC9A3). Biochimica et biophysica acta, 2007, Volume: 1768, Issue:7 Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport Systems; Caco-2 Cells; Caffeine; Dipeptides; Humans; Hydrogen-Ion Concentration; Pentoxifylline; Peptide Transporter 1; Phosphodiesterase Inhibitors; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Symporters; Theophylline	2007
A framework to investigate drug release variability arising from hypromellose viscosity specifications in controlled release matrix tablets. Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:6 Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Hydrochlorothiazide; Hypromellose Derivatives; Kinetics; Lactose; Methylcellulose; Models, Chemical; Molecular Weight; Pentoxifylline; Pharmaceutical Preparations; Solubility; Tablets; Technology, Pharmaceutical; Theophylline; Viscosity	2008
Caffeine, pentoxifylline and theophylline form stacking complexes with IQ-type heterocyclic aromatic amines. Bioorganic chemistry, 2011, Volume: 39, Issue:1 Topics: Amines; Caffeine; Calorimetry; Carcinogens; Heterocyclic Compounds; Mutagenicity Tests; Pentoxifylline; Salmonella typhimurium; Spectrum Analysis; Theophylline; Vibrio; Xanthines	2011
cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma. Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:2 Topics: Animals; Benzenesulfonates; Bucladesine; Carcinoma, Renal Cell; Cell Line; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cytosol; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Hydroquinones; Kidney Neoplasms; Male; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Niacinamide; Pentoxifylline; Phenylurea Compounds; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Pyridines; Rats; RNA, Small Interfering; Signal Transduction; Sorafenib; Theophylline; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins	2011
Sperm motility activation in the critically endangered booroolong frog: the effect of medium osmolality and phosphodiesterase inhibitors. Reproduction, fertility, and development, 2017, Volume: 29, Issue:11 Topics: Animals; Anura; Caffeine; Fertilization in Vitro; Male; Osmolar Concentration; Pentoxifylline; Phosphodiesterase Inhibitors; Semen Analysis; Sperm Motility; Spermatozoa; Theophylline	2017
Identifying drugs with disease-modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology. Pharmacoepidemiology and drug safety, 2020, Volume: 29, Issue:8 Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Artificial Intelligence; Case-Control Studies; Dexamethasone; Female; Humans; Insurance Claim Review; Male; Ontario; Parkinson Disease; Pentoxifylline; Pharmacoepidemiology; Theophylline	2020
Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells. International journal of molecular sciences, 2020, Nov-27, Volume: 21, Issue:23 Topics: Alzheimer Disease; Caffeine; Cell Line, Tumor; Gene Expression Regulation; Genes, Essential; Humans; Neuroblastoma; Pentoxifylline; Principal Component Analysis; Theobromine; Theophylline; Transcription, Genetic; Xanthines	2020
Pentoxifylline or theophylline use in hospitalized COVID-19 patients requiring oxygen support. The clinical respiratory journal, 2021, Volume: 15, Issue:7 Topics: Adult; COVID-19; Humans; Oxygen; Pentoxifylline; Retrospective Studies; RNA, Viral; SARS-CoV-2; Theophylline; Treatment Outcome	2021
Impacts of anti-inflammatory phosphodiesterase inhibitors on a murine model of chronic pulmonary inflammation. Pharmacology research & perspectives, 2021, Volume: 9, Issue:4 Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Cyclopropanes; Disease Models, Animal; Histone Deacetylase 2; Interleukin-8; Lung; Male; Mice, Inbred C57BL; Nicotiana; Pentoxifylline; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Smoke; Smoking; Theophylline; Tumor Necrosis Factor-alpha	2021
Methylxanthines Induce a Change in the AD/Neurodegeneration-Linked Lipid Profile in Neuroblastoma Cells. International journal of molecular sciences, 2022, Feb-18, Volume: 23, Issue:4 Topics: Alzheimer Disease; Caffeine; Cell Line, Tumor; Cholesterol; Humans; Lipids; Neural Stem Cells; Neuroblastoma; Neurodegenerative Diseases; Pentoxifylline; Theobromine; Theophylline; Triglycerides; Xanthines	2022