theophylline and pentostatin

theophylline has been researched along with pentostatin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lichtenstein, LM; Peachell, PT; Schleimer, RP1
Chagoya de Sanchez, V; Souness, JE; Stouffer, JE1
Krnjević, K; Zhu, PJ1
Ito, S; Mikawa, H; Tsuruta, S1
Franklin, PH; Murray, TF; Zhang, G1
Byrd, JC; Flinn, IW; Goodrich, A; Grever, MR; Lucas, MA; Park, K; Shinn, C; Waselenko, JK; Willis, CR1
Adanin, S; Jonjev, ZS; Law, WR; Nardulli, BA; Sam, AD; Yalovetskiy, IV1
Byrd, JC; Diehl, LF; Flinn, IW; Goodrich, A; Grever, MR; Lucas, M; Park, K; Reese, A; Waselenko, JK; Willis, CR1

Reviews

1 review(s) available for theophylline and pentostatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for theophylline and pentostatin

ArticleYear
A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.
    Annals of hematology, 2006, Volume: 85, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Maximum Tolerated Dose; Middle Aged; Pentostatin; Recurrence; Remission Induction; Survival Rate; Theophylline

2006

Other Studies

10 other study(ies) available for theophylline and pentostatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Inhibition by adenosine of histamine and leukotriene release from human basophils.
    Biochemical pharmacology, 1989, Jun-01, Volume: 38, Issue:11

    Topics: 2-Chloroadenosine; Adenosine; Basophils; Coformycin; Histamine Release; Humans; In Vitro Techniques; Pentostatin; SRS-A; Structure-Activity Relationship; Theophylline

1989
Effect of N6-methyladenosine on fat-cell glucose metabolism. Evidence for two modes of action.
    Biochemical pharmacology, 1982, Dec-15, Volume: 31, Issue:24

    Topics: Adenosine; Adipose Tissue; Animals; Coformycin; Cyclic AMP; Fatty Acids; Glucose; Glycerol; In Vitro Techniques; Male; Nucleosides; Oxidation-Reduction; Pentostatin; Rats; Rats, Inbred Strains; Theophylline

1982
Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions.
    Neuroscience, 1994, Volume: 63, Issue:2

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Electrophysiology; Hippocampus; Hypoxia; Pentostatin; Rats; Rats, Sprague-Dawley; Reference Values; Synaptic Transmission; Theophylline

1994
Effects of adenosine and its analogues on actin polymerization in human polymorphonuclear leucocytes.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:2

    Topics: Actins; Adenosine; Adenosine Deaminase; Biopolymers; Complement C5a; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Platelet Activating Factor; Theophylline

1993
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicuculline; Cerebral Cortex; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Seizures; Theophylline; Thioinosine

1993
Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders.
    Seminars in oncology, 2000, Volume: 27, Issue:2 Suppl 5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cause of Death; Chlorambucil; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease Progression; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Immunosuppressive Agents; Leukemia; Lymphoma; Neoplasm Recurrence, Local; Pentostatin; Phosphodiesterase Inhibitors; Theophylline

2000
Inhibiting adenosine deaminase modulates the systemic inflammatory response syndrome in endotoxemia and sepsis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:5

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Bacterial Infections; Blood; Chronic Disease; Endotoxemia; Enzyme Inhibitors; Inflammation; Interleukin-1; Interleukin-10; Liver; Male; Pentostatin; Peroxides; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spleen; Theophylline; Tumor Necrosis Factor-alpha

2002