theophylline has been researched along with pefloxacin in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Christ, W | 1 |
| Kawane, H; Niki, Y; Soejima, R; Sumi, M; Umeki, S | 1 |
| Baars, AM; van Herwaarden, CL; Vree, TB; Wijnands, WJ | 2 |
| Bouquet, S; Couet, W; Delon, A; Faury, P; Greco, WR; Levasseur, LM | 1 |
| Bois, FY; Brochot, C; Couet, W; Gelman, A; Marchand, S | 1 |
12 other study(ies) available for theophylline and pefloxacin
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Central nervous system toxicity of quinolones: human and animal findings.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Ciprofloxacin; Dogs; Drug Interactions; Fleroxacin; Fluoroquinolones; gamma-Aminobutyric Acid; Humans; Injections, Intraventricular; Narcotic Antagonists; Pefloxacin; Quinolizines; Seizures; Theophylline | 1990 |
New synthetic quinolone antibacterial agents and serum concentration of theophylline.
Topics: Adult; Anti-Infective Agents; Chemical Phenomena; Chemistry; Ciprofloxacin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Pipemidic Acid; Theophylline | 1987 |
Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Enoxacin; Female; Humans; Male; Middle Aged; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
The influence of the 4-quinolones ciprofloxacin, pefloxacin and ofloxacin on the elimination of theophylline.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Middle Aged; Norfloxacin; Ofloxacin; Oxazines; Pefloxacin; Quinolines; Theophylline | 1987 |
Development of a new quantitative approach for the isobolographic assessment of the convulsant interaction between pefloxacin and theophylline in rats.
Topics: Animals; Anti-Infective Agents; Drug Interactions; Male; Mathematical Computing; Models, Biological; Monte Carlo Method; Pefloxacin; Rats; Rats, Sprague-Dawley; Seizures; Theophylline; Vasodilator Agents | 1998 |
Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats.
Topics: Animals; Drug Interactions; Male; Norfloxacin; Pefloxacin; Rats; Rats, Sprague-Dawley; Seizures; Theophylline | 2004 |