theophylline has been researched along with naloxone in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (44.78) | 18.7374 |
| 1990's | 9 (13.43) | 18.2507 |
| 2000's | 18 (26.87) | 29.6817 |
| 2010's | 8 (11.94) | 24.3611 |
| 2020's | 2 (2.99) | 2.80 |
| Authors | Studies |
|---|---|
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Barlow, D; Ciarlo, L; Dimmito, MP; Houseknecht, KL; Lei, W; Macedonio, G; Mollica, A; Novellino, E; Pieretti, S; Stefanucci, A; Streicher, JM | 1 |
| Paalzow, G | 1 |
| Collier, HO; Francis, DL; Roy, AC | 1 |
| Butt, NM; Collier, HO; Cuthbert, NJ; Francis, DL; Saeed, SA | 1 |
| Bhargava, HN; Ho, LK; Loh, HH; Way, EL | 1 |
| De Koninck, Y; Henry, JL | 1 |
| Locke, RG; Salvia, JV | 1 |
| DeLander, GE; Hopkins, CJ | 1 |
| Doi, T; Kuzuna, S; Maki, Y | 1 |
| Kleven, MS; Sparber, SB | 1 |
| Baba, S; Takeda, T; Tanaka, C; Taniyama, K | 1 |
| Puurunen, J | 1 |
| Lombard, RM; Zwillich, CW | 1 |
| Otsuka, H | 1 |
| Dowell, RT; Eldridge, FL; Paydarfar, D; Scott, SC | 1 |
| Arslan, P; Foresta, C; Scandellari, C; Tramarin, A | 1 |
| Barthó, L; Holzer, P; Lippe, IT; Saria, A | 1 |
| Henry, JL; Salter, MW | 1 |
| Askew, WE; Charalampous, KD | 1 |
| Ho, IK; Loh, HH; Way, EL | 1 |
| Collier, HO | 1 |
| Collier, HO; Francis, DL; Henderson, G; Schneider, C | 1 |
| Collier, HO; Tucker, JF | 1 |
| Collier, HO; Cuthbert, NJ; Francis, DL | 1 |
| Galloway, MP; Roth, RH | 1 |
| Grant, SJ; Redmond, DE | 1 |
| Beubler, E; Lembeck, F | 1 |
| Kandasamy, SB; Williams, BA | 3 |
| Contreras, E; Juica, S; Tamayo, L | 1 |
| Brailowsky, S; Guerrero-Muñoz, F; Luján, M; Shkurovich, M | 1 |
| McQueen, DS; Ribeiro, JA | 1 |
| Gabrilovac, J | 1 |
| Kromer, W | 1 |
| Joran, ME; Murphy, DJ; Renninger, JE | 1 |
| Begnini, J; Bellot, RG; De-La-Vega, DD; Frussa-Filho, R; Jimenez-Bernal, RE; Lopes, FP; Mello, CF; Schwartz, CC | 1 |
| Adeghate, E; Djali, PK; Singh, J | 1 |
| Gautier, H; Murariu, C | 1 |
| Capasso, A | 1 |
| Hasegawa, T; Itoh, A; Mamiya, T; Nabeshima, T; Nakayama, S; Noda, Y; Shiotani, T | 1 |
| Rao, VS; Santos, FA | 1 |
| Arai, I; Hashimoto, Y; Kurachi, M; Takano, N | 1 |
| Galligan, JJ; Ren, J | 1 |
| Kato, M; Mobarakeh, JI; Nishino, S; Sakurada, S; Takahashi, K; Watanabe, H; Yanai, K | 1 |
| Amico, MC; Morrone, LA; Palmery, M; Romanelli, L; Tucci, P; Valeri, P | 2 |
| Cavalcante, IJ; Lima, MA; Maia, JL; Melo, CM; Rao, VS; Santos, FA; Silveira, ER; Vieira, GA | 1 |
| Baird, JC; Kraemer, WJ; Mahler, DA; Murray, JA; Ward, J; Waterman, LA; Zhang, X | 1 |
| Capasso, A; Gallo, C | 1 |
| Berdeaux, A; Chenoune, M; Cohen, MV; Darbera, L; Downey, JM; Ghaleh, B; Lidouren, F; Tissier, R | 1 |
| Beardsley, PM; Elder, HJ; Walentiny, DM | 1 |
5 review(s) available for theophylline and naloxone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacologic manipulation of the respiratory control center in the infant.
Topics: Almitrine; Doxapram; Drug Therapy; Humans; Infant; Infant, Newborn; Naloxone; Progesterone; Prostaglandins; Respiratory Center; Respiratory Insufficiency; Respiratory Muscles; Theophylline | 1990 |
Medical therapy of obstructive sleep apnea.
Topics: Almitrine; Central Nervous System Stimulants; Diet, Reducing; Humans; Intubation; Male; Naloxone; Nasopharynx; Obesity; Oxygen Inhalation Therapy; Piperazines; Positive-Pressure Respiration; Progesterone; Protriptyline; Sleep Apnea Syndromes; Theophylline | 1985 |
[Are respiratory stimulants necessary? Yes].
Topics: Almitrine; Central Nervous System Stimulants; Doxapram; Humans; Naloxone; Piperazines; Progesterone; Respiration, Artificial; Respiratory Insufficiency; Theophylline | 1987 |
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
1 trial(s) available for theophylline and naloxone
| Article | Year |
|---|---|
Endogenous opioids modify dyspnoea during treadmill exercise in patients with COPD.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; beta-Endorphin; Bronchodilator Agents; Double-Blind Method; Dyspnea; Exercise Test; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid Peptides; Oxygen Consumption; Pulmonary Disease, Chronic Obstructive; Spirometry; Theophylline | 2009 |
61 other study(ies) available for theophylline and naloxone
| Article | Year |
|---|---|
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.
Topics: Administration, Intravenous; Analgesics, Opioid; Animals; CHO Cells; Cricetulus; Female; Humans; Infusions, Subcutaneous; Male; Mice; Models, Molecular; Opioid Peptides; Pain; Peptides, Cyclic; Receptors, Opioid | 2020 |
Naloxone antagonizes theophylline-induced potentiation of morphine inhibition of a nociceptive reaction in rats.
Topics: Analgesics; Animals; Drug Interactions; Electric Stimulation; Male; Morphine; Naloxone; Pimozide; Rats; Theophylline; Time Factors; Vocalization, Animal | 1979 |
Morphone abstinence and quasi-abstinence effects after phosphodiesterase inhibitors and naloxone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Morphine; Naloxone; Phosphodiesterase Inhibitors; Prostaglandins; Rats; Structure-Activity Relationship; Substance Withdrawal Syndrome; Theophylline; Time Factors; Xanthines | 1975 |
Mechanism of quasi-morphine withdrawal behaviour induced by methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Humans; Male; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Xanthines | 1979 |
Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Cyclic GMP; Cycloheximide; Drug Tolerance; Humans; Mice; Morphine; Naloxone; Phosphodiesterase Inhibitors; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline | 1975 |
Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord.
Topics: Adenosine; Adenosine Monophosphate; Animals; Bicuculline; Cats; Evoked Potentials; Iontophoresis; Membrane Potentials; Naloxone; Neurons; Pain; Physical Stimulation; Purinergic Antagonists; Spinal Cord; Strychnine; Synapses; Theophylline; Vibration | 1992 |
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines | 1986 |
Spinal antinociceptive effects of adenosine compounds in mice.
Topics: Adenine Nucleotides; Adenosine; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Substance P; Theophylline | 1987 |
Morphine blocks and naloxone enhances suppression of operant behavior by low doses of 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Body Temperature; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Theophylline | 1989 |
Putative mechanisms involved in excitatory and inhibitory effects of somatostatin on intestinal motility.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; Female; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Somatostatin; Theophylline; Yohimbine | 1989 |
Role of putative neurotransmitters in the central gastric antisecretory effect of prostaglandin E2 in rats.
Topics: 5,6-Dihydroxytryptamine; Adrenergic alpha-Antagonists; Animals; Dinoprostone; Dioxanes; Female; Fenclonine; Gastric Juice; Histamine Antagonists; Hydroxydopamines; Idazoxan; Injections, Intraventricular; Male; Naloxone; Neurotransmitter Agents; Oxidopamine; Phentolamine; Propranolol; Prostaglandins E; Rats; Rats, Inbred Strains; Sulpiride; Theophylline | 1985 |
Role of endogenous adenosine in recurrent generalized seizures.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Cats; Cerebral Cortex; Dipyridamole; Doxapram; Naloxone; Penicillins; Receptors, Purinergic; Reference Values; Seizures; Theophylline | 1989 |
Effects of a met-enkephalin analogue on motility, O2 consumption, and ATP content of human spermatozoa.
Topics: Adenosine Triphosphate; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Survival; Cyclic AMP; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Humans; Male; Naloxone; Oligomycins; Oxygen Consumption; Sperm Motility; Spermatozoa; Theophylline; Time Factors | 1985 |
Neuropeptide Y inhibits excitatory enteric neurons supplying the circular muscle of the guinea pig small intestine.
Topics: Animals; Apamin; Atropine; Ceruletide; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Female; Guanethidine; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Neurons; Neuropeptide Y; Phentolamine; Reflex; Theophylline | 1987 |
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration | 1987 |
Effect of non-opiate antagonists on stereospecific opiate receptor binding of tritiated naloxone.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Binding, Competitive; Brain; Bucladesine; Filtration; Fluorides; Isoproterenol; Levorphanol; Male; Mice; Naloxone; Phenoxybenzamine; Pimozide; Propranolol; Receptors, Drug; Structure-Activity Relationship; Theophylline; Tritium | 1974 |
Effect of cyclic AMP on morphine analgesia tolerance and physical dependence.
Topics: Analgesia; Animals; Cyclic AMP; Drug Tolerance; Humans; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome; Theophylline | 1972 |
The concept of the quasi-abstinence effect and its use in the investigation of dependence mechanisms.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Hormones; Humans; Naloxone; Phosphodiesterase Inhibitors; Rats; Serotonin; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline | 1974 |
Quasi morphine-abstinence syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; Drug Synergism; Heroin; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Rats; Substance Withdrawal Syndrome; Theophylline | 1974 |
Character and meaning of quasi-morphine withdrawal phenomena elicited by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Humans; Hypoxanthines; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Phosphodiesterase Inhibitors; Pyrimidines; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Triazoles; Xanthines | 1981 |
Clonidine prevents methylxanthine stimulation of norepinephrine metabolism in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Brain; Cerebellum; Clonidine; Diazepam; Hippocampus; Kinetics; Male; Naloxone; Norepinephrine; Rats; Rats, Inbred Strains; Theophylline | 1983 |
Clonidine suppresses methylxanthine induced quasi-morphine withdrawal syndrome.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Behavior, Animal; Clonidine; Humans; Male; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome; Theophylline | 1982 |
Inhibition by morphine of prostaglandin E1-stimulated secretion and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum in vivo.
Topics: Alprostadil; Animals; Antidiarrheals; Body Water; Cyclic AMP; Female; Intestinal Secretions; Jejunum; Morphine; Naloxone; Prostaglandins E; Rats; Rats, Inbred Strains; Theophylline | 1980 |
Cholecystokinin-octapeptide-induced hyperthermia in guinea-pigs.
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Injections, Intraventricular; Male; Naloxone; Phenoxybenzamine; Sincalide; Theophylline | 1983 |
Hyperthermic effects of centrally injected (D-ala2, N-Me-Phe4, Met-(O)5-ol)-enkephalin (FK 33-824) in rabbits and guinea-pigs.
Topics: Animals; Body Temperature; Cyclic AMP; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Guinea Pigs; Indomethacin; Injections, Intraventricular; Male; Naloxone; Norepinephrine; Phenoxybenzamine; Prostaglandins; Rabbits; Theophylline | 1983 |
Hyperthermic responses to central injections of some peptide and non-peptide opioids in the guinea-pig.
Topics: Animals; Body Temperature; Endorphins; Fever; Guinea Pigs; Indomethacin; Iodipamide; Naloxone; Narcotics; Norepinephrine; Phenoxybenzamine; Theophylline | 1983 |
Sensitivity changes after morphine treatment in the mouse uterus.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Drug Tolerance; Female; In Vitro Techniques; Mice; Morphine; Naloxone; Serotonin; Theophylline; Uterine Contraction | 1982 |
Morphine-theophylline interaction: antagonism or facilitation?
Topics: Animals; Calcium; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Lethal Dose 50; Mice; Morphine; Motor Activity; Naloxone; Synaptosomes; Theophylline | 1981 |
Effect of adenosine on carotid chemoreceptor activity in the cat.
Topics: Adenosine; Aminophylline; Animals; Carotid Arteries; Cats; Chemoreceptor Cells; Electrophysiology; Female; Male; Naloxone; Theophylline | 1981 |
Leu-enkephalin modulates the migration inhibition of mouse splenocytes induced by cAMP-elevating agents.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Migration Inhibition; Cell Movement; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; In Vitro Techniques; Mice; Mice, Inbred CBA; Naloxone; Spleen; Theophylline | 1993 |
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline | 1995 |
Effects of adenosine agonists and antagonists on pulmonary ventilation in conscious rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Bronchoconstriction; Bronchodilator Agents; Lung; Male; Naloxone; Narcotics; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Theophylline; Vasodilator Agents; Xanthines | 1993 |
Antinociceptive effect of purine nucleotides.
Topics: Analgesics; Animals; Caffeine; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Purine Nucleotides; Quinidine; Receptors, Purinergic P1; Receptors, Purinergic P2; Rosaniline Dyes; Suramin; Theophylline | 1996 |
Immunohistochemistry and secretory effects of leucine enkephalin in the isolated pig lacrimal gland.
Topics: Animals; Atropine; Enkephalin, Leucine; Eye Proteins; Female; Immunohistochemistry; In Vitro Techniques; Lacrimal Apparatus; Male; Naloxone; Neurons; Perfusion; Phentolamine; Propranolol; Swine; Theophylline | 1998 |
Neuromodulators and hypoxic hypothermia in the rat.
Topics: Adenosine; Animals; Body Temperature; Carbon Monoxide; Hypothermia; Hypoxia; Male; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Theophylline | 1998 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2000 |
Attenuation of the development of morphine dependence/tolerance by nefiracetam: involvement of adenosine 3':5'-cyclic monophosphate system.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Cyclic AMP; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Phosphodiesterase Inhibitors; Psychotropic Drugs; Pyrrolidinones; Substance Withdrawal Syndrome; Theophylline; Xanthines | 2000 |
Possible role of mast cells in cineole-induced scratching behavior in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Cyclohexanols; Cyproheptadine; Diphenhydramine; Eucalyptol; Histamine H1 Antagonists; Male; Mast Cells; Mice; Monoterpenes; Naloxone; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Serotonin Antagonists; Terpenes; Theophylline | 2002 |
Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice.
Topics: Alprostadil; Animals; Antipruritics; Behavior, Animal; Capsaicin; Chlorpheniramine; Cyproheptadine; Dermatitis, Atopic; Dexamethasone; Dibucaine; Male; Mice; Mice, Inbred Strains; Naloxone; Pinacidil; Pruritus; Tacrolimus; Theophylline; Time Factors | 2004 |
Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum.
Topics: Acetylcholine; Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Animals; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Estriol; Excitatory Postsynaptic Potentials; GABA Antagonists; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Iontophoresis; Male; Mecamylamine; Myenteric Plexus; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Nicotinic Antagonists; Peptides; Picrotoxin; Piperazines; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Serotonin 5-HT1 Receptor Antagonists; Theophylline; Time Factors | 2005 |
Enhanced antinociception by intracerebroventricularly and intrathecally-administered orexin A and B (hypocretin-1 and -2) in mice.
Topics: Analgesics; Animals; Gene Expression; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Neuropeptides; Nociceptin; Opioid Peptides; Orexin Receptors; Orexins; Pain Measurement; Purinergic P1 Receptor Antagonists; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Theophylline; Xanthines | 2005 |
Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Cholecystokinin; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Receptor, Adenosine A1; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Theophylline | 2005 |
Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Benzoxazines; Cholecystokinin; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naloxone; Naphthalenes; Narcotic Antagonists; Neurons; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rimonabant; Substance Withdrawal Syndrome; Theophylline | 2005 |
12-Acetoxyhawtriwaic acid lactone, a diterpene from Egletes viscosa, attenuates capsaicin-induced ear edema and hindpaw nociception in mice: possible mechanisms.
Topics: Analgesics; Animals; Asteraceae; Capsaicin; Diterpenes; Diterpenes, Clerodane; Ear; Edema; Flowers; Glyburide; Hindlimb; Lactones; Male; Mice; Naloxone; Nociceptors; Substance P; Theophylline; TRPV Cation Channels | 2006 |
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2009 |
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial Infarction; Naloxone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Opioid; Receptors, Purinergic P1; Theophylline; Time Factors | 2012 |
Theophylline reverses oxycodone's but not fentanyl's respiratory depression in mice while caffeine is ineffective against both opioids.
Topics: Analgesics, Opioid; Animals; Caffeine; Fentanyl; Male; Mice; Naloxone; Narcotic Antagonists; Oxycodone; Respiratory Insufficiency; Theophylline | 2023 |