theophylline has been researched along with n(6)-cyclopentyladenosine in 81 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.23) | 18.7374 |
| 1990's | 52 (64.20) | 18.2507 |
| 2000's | 23 (28.40) | 29.6817 |
| 2010's | 5 (6.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, A; Nonaka, H; Shimada, J; Suzuki, F | 1 |
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Bey, P; Demeter, DA; Dudley, MW; Lentz, NL; Meng, EC; Ogden, AM; Peet, NP; Weintraub, HJ | 1 |
| Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD | 1 |
| Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| El-Tayeb, A; Inamdar, GS; Li, W; Müller, CE; Scheiff, AB; Sudarsanam, V; Vasu, KK; Yerande, SG | 1 |
| Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Garaschuk, O; Kovalchuk, Yu; Krishtal, O | 1 |
| Brink, A; Fuder, H; Meincke, M; Tauber, U | 1 |
| Fredholm, BB; Gerwins, P | 1 |
| Földes, FF; Nagano, O; Nakatsuka, H; Ohta, Y; Reich, D; Sperlagh, B; Vizi, ES | 1 |
| Abramson, SB; Cronstein, BN; Hirschhorn, R; Levin, RI; Philips, M; Weissmann, G | 1 |
| Kurth, CD; Wagerle, LC | 1 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Contreras, E; Germany, A | 1 |
| Cronstein, BN; Salmon, JE | 1 |
| Durcan, MJ; Morgan, PF | 1 |
| Huguenard, JR; Ulrich, D | 1 |
| Burnstock, G; Ralevic, V; Rubino, A | 1 |
| Appel, S; Danhof, M; IJzerman, AP; Langemeijer, MW; Mathôt, RA | 1 |
| He, RR; Li, YL | 2 |
| Bickler, PE; Buck, LT | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K | 1 |
| Apaya, RP; IJzerman, AP; Price, SL; Soudijn, W; van der Wenden, EM | 1 |
| Martin, PL; Potts, AA | 1 |
| Delle Donne, KT; Sonsalla, PK | 1 |
| de Carolis, AS; Pèzzola, A; Popoli, P | 1 |
| Crosson, CE; DeBenedetto, R; Gidday, JM | 1 |
| Carruthers, AM; Fozard, JR | 2 |
| Appel, S; Danhof, M; IJzerman, AP; Mathôt, RA; Soudijn, W; van Schaick, EA | 1 |
| Bartus, RT; Jacobson, KA; Paul, IA; Von Lubitz, DK | 1 |
| Frisella, WA; Sturm, CD; Yoon, KW | 1 |
| Joad, JP; Kott, KS | 1 |
| Bruns, RF; Montamat, SC; Mudumbi, RV; Vestal, RE | 1 |
| Adeyemo, O; Buchanan, P; Jain, N; Kemp, N; Stone, TW | 1 |
| Ali, S; Metzger, WJ; Mustafa, SJ | 1 |
| Nilsson, GE; Sundin, L | 1 |
| Hettinger-Smith, BD; Leid, M; Murray, TF | 1 |
| DeLander, GE; Keil, GJ | 1 |
| Abe, T; Gutterman, DD; Morgan, DA | 1 |
| Broadley, KJ; Maddock, HL | 1 |
| Friedman, E; Gao, E; Horwitz, J; Johnson, MD; Roberts, J; Snyder, DL | 1 |
| Byford, AM; Gauthier, NS; Headrick, JP; Linden, J; Matherne, GP | 1 |
| Broadley, KJ; Ford, WR | 1 |
| Chopde, CT; Ghosh, AK; Mandhane, SN | 1 |
| Hettinger, BD; Leid, M; Murray, TF | 1 |
| Bockaert, J; Manzoni, O; Pujalte, D; Williams, J | 1 |
| Beukers, MW; Dalpiaz, A; IJzerman, AP; Schofield, PR; Townsend-Nicholson, A | 1 |
| Gupta, YK; Malhotra, J | 2 |
| Lambertz, M; Langer, SF; Langhorst, P; Schmidt, HD | 1 |
| Kitamura, Y; Matsuoka, Y; Ohta, S; Okazaki, M; Sekino, Y; Takata, K; Taniguchi, T | 1 |
| Broadley, KJ; Gardner, NM | 1 |
| Capasso, A | 1 |
| Martinez-Tica, JF; Zornow, MH | 1 |
| Georgiev, V; Kambourova, T; Tchekalarova, J | 1 |
| Hamann, M; Richter, A | 1 |
| Cheng, JT; Chi, TC; Liu, IM | 1 |
| Othman, T; Rivkees, SA; Schwartz, M; Turner, CP; Yan, H | 1 |
| Rao, VS; Santos, FA | 1 |
| Homayoun, H; Khavandgar, S; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Lobner, D | 1 |
| Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
| Kimura, M; Saitoh, N; Takahashi, T | 1 |
| Bueters, TJ; Joosen, MJ; van Helden, HP | 1 |
| Antoniou, K; Ferre, S; Goldberg, SR; Highkin, JL; Hockemeyer, J; Justinova, Z; Munzar, P; Pappas, LA; Segal, PN; Solinas, M | 1 |
| Ho, CM; Ho, ST; Peng, SC; Su, CK; Tsai, SK | 1 |
| Herrero, JF; Ramos-Zepeda, G; Rosenow, S; Schröder, W | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Sato, K | 1 |
| Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Müller, CE; Schindler, CW; Tella, SR; Thorndike, EB | 1 |
| de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA | 1 |
| Georgiev, VP; Pechlivanova, DM | 1 |
| Brown, R; Fredholm, BB; Lai, EY; Mrowka, R; Patzak, A; Persson, AE; Persson, PB; Spielmann, N; Steege, A | 1 |
| Fan, W; Kaplan, GB; Klufas, MA; Leite-Morris, KA | 1 |
| Capasso, A; Gallo, C | 1 |
| Berdeaux, A; Chenoune, M; Cohen, MV; Darbera, L; Downey, JM; Ghaleh, B; Lidouren, F; Tissier, R | 1 |
| Ichinose, TK; Li, C; Minic, Z; O'Leary, DS; Scislo, TJ | 1 |
2 review(s) available for theophylline and n(6)-cyclopentyladenosine
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
Fluorescent ligands for adenosine receptors.
Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 2013 |
79 other study(ies) available for theophylline and n(6)-cyclopentyladenosine
| Article | Year |
|---|---|
8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; Corpus Striatum; Guinea Pigs; Humans; Molecular Conformation; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Receptors, Purinergic; Stereoisomerism; Structure-Activity Relationship; Xanthines | 1992 |
A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.
Topics: Adenosine; Animals; Dogs; Humans; Molecular Conformation; Molecular Structure; Protein Binding; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines | 1990 |
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity | 1994 |
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines | 1998 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.
Topics: Adenosine A1 Receptor Antagonists; Animals; Drug Design; Humans; Molecular Structure; Rats; Receptor, Adenosine A1; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 2010 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Adenosine-dependent enhancement by methylxanthines of excitatory synaptic transmission in hippocampus of rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Theophylline | 1992 |
Purinoceptor-mediated modulation by endogenous and exogenous agonists of stimulation-evoked [3H]noradrenaline release on rat iris.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Iris; Male; Norepinephrine; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synaptic Transmission; Theophylline; Xanthines | 1992 |
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Muscle, Smooth; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Type C Phospholipases; Virulence Factors, Bordetella | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; Dipyridamole; Electric Stimulation; In Vitro Techniques; Magnesium; Male; Mice; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Purinergic Antagonists; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline; Tritium; Tubocurarine; Xanthines | 1992 |
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens, CD; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Humans; Macrophage-1 Antigen; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1992 |
Cerebrovascular reactivity to adenosine analogues in 0.6-0.7 gestation and near-term fetal sheep.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Cerebrovascular Circulation; Female; Fetus; Gestational Age; Pregnancy; Sheep; Theophylline; Vasodilator Agents | 1992 |
Adenosine receptors involved in the inhibitory control of non-adrenergic non-cholinergic neurotransmission in guinea-pig atria belong to the A1 subtype.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Atrial Function; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Male; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Reserpine; Synaptic Transmission; Theophylline | 1991 |
Adenosine analogs attenuate tolerance-dependence on alprazolam.
Topics: Adenosine; Alprazolam; Animals; Drug Tolerance; Male; Mice; Phenylisopropyladenosine; Substance-Related Disorders; Theophylline | 1991 |
Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antigens, Differentiation; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Humans; In Vitro Techniques; Neutrophils; Pertussis Toxin; Phagocytosis; Phenylisopropyladenosine; Receptors, Fc; Receptors, IgG; Receptors, Purinergic; Superoxides; Theophylline; Virulence Factors, Bordetella | 1990 |
NECA-induced hypomotility in mice: evidence for a predominantly central site of action.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Central Nervous System; Male; Mice; Motor Activity; Receptors, Purinergic; Theophylline | 1989 |
Purinergic inhibition of GABA and glutamate release in the thalamus: implications for thalamic network activity.
Topics: Adenosine; Animals; Bicuculline; Electric Conductivity; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Quinoxalines; Rats; Receptors, Purinergic P1; Synapses; Thalamus; Theophylline | 1995 |
Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline.
Topics: Adenosine; Animals; Blood Pressure; Blood Proteins; Heart Rate; Male; Models, Chemical; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1995 |
Effects of N6-cyclopentyladenosine on afterdepolarizations and triggered activity induced by isoproterenol in guinea pig papillary muscle.
Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Papillary Muscles; Theophylline | 1995 |
Role of adenosine in NMDA receptor modulation in the cerebral cortex of an anoxia-tolerant turtle (Chrysemys picta belli).
Topics: Adenosine; Animals; Calcium; Cerebral Cortex; Female; Fluorometry; Fura-2; Glutamates; Hypoxia, Brain; Male; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Theophylline; Turtles | 1995 |
Effects of xanthine derivatives in a light/dark test in mice and the contribution of adenosine receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Interactions; Light; Male; Mice; Phenethylamines; Purinergic P1 Receptor Antagonists; Structure-Activity Relationship; Theophylline; Xanthines | 1994 |
Relative binding orientations of adenosine A1 receptor ligands--a test case for Distributed Multipole Analysis in medicinal chemistry.
Topics: Adenosine; Computer Graphics; Drug Design; Electrochemistry; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Xanthines | 1995 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; MPTP Poisoning; Receptors, Purinergic P1; Theophylline; Tyrosine 3-Monooxygenase | 1994 |
Electrophysiological effects of N6-cyclopentyl-adenosine and [-]-N6-[phenylisopropyl]-adenosine on pacemaker cells in sinoatrial node of guinea pigs.
Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Female; Glyburide; Guinea Pigs; Male; Microelectrodes; Phenylisopropyladenosine; Sinoatrial Node; Theophylline | 1993 |
Modulation of striatal adenosine A1 and A2 receptors induces rotational behaviour in response to dopaminergic stimulation in intact rats.
Topics: Adenosine; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dopamine; Injections, Intraperitoneal; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1994 |
Functional evidence for retinal adenosine receptors.
Topics: Adenosine; Animals; Cattle; Dopamine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Receptors, Purinergic P1; Retina; Retinal Vessels; Swine; Theophylline; Vasodilation | 1994 |
The cardiovascular effects of selective adenosine A1 and A2 receptor agonists in the pithed rat: no role for glibenclamide-sensitive potassium channels.
Topics: Adenosine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cardiovascular System; Cyclopentanes; Glyburide; Heart Rate; Male; Parasympatholytics; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Sensitivity and Specificity; Theophylline; Time Factors | 1993 |
High-performance liquid chromatography of the adenosine A1 agonist N6-cyclopentyladenosine and the A1 antagonist 8-cyclopentyltheophylline and its application in a pharmacokinetic study in rats.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Ligands; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1993 |
Effect of pertussis toxin treatment on the putative adenosine A3 receptor-mediated hypotensive response in the rat.
Topics: Adenosine; Adenylate Cyclase Toxin; Animals; Blood Pressure; CHO Cells; Cricetinae; Heart Rate; Male; Pertussis Toxin; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Virulence Factors, Bordetella | 1993 |
Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Spatial Behavior; Theophylline | 1993 |
Attenuation of potassium cyanide-mediated neuronal cell death by adenosine.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Neurons; Osmolar Concentration; Potassium Cyanide; Purinergic Antagonists; Theobromine; Theophylline | 1993 |
Effect of adenosine receptor ligands on cAMP content in human airways and peripheral lung.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Aged; Child; Cromolyn Sodium; Cyclic AMP; Female; Humans; Ligands; Lung; Male; Middle Aged; Phenethylamines; Receptors, Purinergic; Respiratory System; Theophylline; Xanthines | 1993 |
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines | 1993 |
Anxiolytic activity of adenosine receptor activation in mice.
Topics: Adenosine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Male; Maze Learning; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
Simultaneous measurement of cyclopentyladenosine-induced contraction and intracellular calcium in bronchial rings from allergic rabbits and it's antagonism.
Topics: Adenosine; Animals; Bronchi; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth; Rabbits; Theophylline | 1996 |
Branchial and systemic roles of adenosine receptors in rainbow trout: an in vivo microscopy study.
Topics: Adenosine; Animals; Blood Circulation; Branchial Region; Female; Male; Oncorhynchus mykiss; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilator Agents | 1996 |
Chronic exposure to adenosine receptor agonists and antagonists reciprocally regulates the A1 adenosine receptor-adenylyl cyclase system in cerebellar granule cells.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cerebellum; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 1996 |
Altered sensory behaviors in mice following manipulation of endogenous spinal adenosine neurotransmission.
Topics: Adenosine; Animals; Deoxyadenosines; Grooming; Male; Mice; Neurotransmitter Agents; Pain; Spinal Cord; Substance P; Theophylline | 1996 |
Role of adenosine receptor subtypes in neural stunning of sympathetic coronary innervation.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Male; Myocardial Stunning; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sympathetic Nervous System; Theobromine; Theophylline; Vasoconstriction; Xanthines | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilation | 1996 |
The effect of age on adenosine A1 receptor function in the rat heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Carbachol; Cardiovascular Agents; Cell Membrane; Colforsin; Heart; Isoproterenol; Male; Muscarinic Agonists; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sulfonic Acids; Theophylline | 1997 |
Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia.
Topics: Adenosine; Analysis of Variance; Animals; Cell Membrane; Coronary Vessels; Female; Heart; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Radioligand Assay; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Theophylline; Vascular Resistance | 1997 |
Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1997 |
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antagonists; Haloperidol; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Scopolamine; Theobromine; Theophylline; Xanthines | 1997 |
Cyclopentyladenosine-induced homologous down-regulation of A1 adenosine receptors (A1AR) in intact neurons is accompanied by receptor sequestration but not a reduction in A1AR mRNA expression or G protein alpha-subunit content.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Cerebellum; Down-Regulation; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Neurons; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Tritium; Xanthines | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyridamole; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Thioinosine; Vasodilator Agents; Xanthines | 1998 |
Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
Topics: Adenosine; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; CHO Cells; Cricetinae; Entropy; Humans; Kinetics; Point Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Theophylline; Thermodynamics; Threonine; Transfection; Xanthines | 1998 |
Effect of adenosinergic modulation on the anticonvulsant effect of phenobarbitone and carbamazepine.
Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Convulsants; Drug Combinations; Male; Pentylenetetrazole; Phenobarbital; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1999 |
Interbeat interval variability in isolated working rat hearts at various dynamic conditions and temperatures.
Topics: Adenosine; Animals; Cardiac Output; Cardiotonic Agents; Chi-Square Distribution; Electrocardiography; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted; Temperature; Theophylline; Vasodilator Agents; Ventricular Function, Left | 1999 |
Endogenous adenosine protects CA1 neurons from kainic acid-induced neuronal cell loss in the rat hippocampus.
Topics: Adenosine; Animals; Apoptosis; Disease Models, Animal; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Histocompatibility Antigens Class II; Injections, Intraventricular; Kainic Acid; Macrophage-1 Antigen; Male; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Phosphorylation; Proto-Oncogene Proteins c-jun; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1999 |
Resistance to antagonism of atrial P(1) purinoceptor responses in the presence of K(+) channel blockade.
Topics: 4-Aminopyridine; Adenosine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Heart Atria; Male; Myocardial Contraction; Potassium Channel Blockers; Propranolol; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Reserpine; Signal Transduction; Theophylline | 1999 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2000 |
Influence of adenosine agonists and antiepileptic drugs on theophylline-induced seizures in rats.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Male; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Seizures; Theophylline | 1998 |
Effects of adenosine agonists and an antagonist on excitatory transmitter release from the ischemic rabbit hippocampus.
Topics: Adenosine; Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Electroencephalography; Extracellular Space; Glutamic Acid; Hippocampus; Hypothermia, Induced; Injections, Intravenous; Microdialysis; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion; Theophylline; Xanthines | 2000 |
Interaction between angiotensin IV and adenosine A(1) receptor related drugs in passive avoidance conditioning in rats.
Topics: 2-Chloroadenosine; Adenosine; Angiotensin II; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
Activation of adenosine A1 receptors by drugs to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Adenosine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Streptozocin; Theophylline; Triglycerides; Xanthines | 2000 |
A1 adenosine receptor activation induces ventriculomegaly and white matter loss.
Topics: Adenosine; Animals; Animals, Newborn; Body Weight; Cell Count; Cerebral Cortex; Cerebral Ventricles; Drug Combinations; Drug Interactions; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Microscopy, Electron; Myelin Basic Protein; Nerve Degeneration; Nerve Fibers, Myelinated; Neuroglia; Neurons; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Telencephalon; Theophylline | 2002 |
Possible role of mast cells in cineole-induced scratching behavior in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Cyclohexanols; Cyproheptadine; Diphenhydramine; Eucalyptol; Histamine H1 Antagonists; Male; Mast Cells; Mice; Monoterpenes; Naloxone; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Serotonin Antagonists; Terpenes; Theophylline | 2002 |
The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics, Opioid; Animals; Learning; Male; Memory; Mice; Morphine; Receptors, Purinergic P1; Theophylline; Vasodilator Agents | 2002 |
Saturation of neuroprotective effects of adenosine in cortical culture.
Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular Space; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2002 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
Topics: Adenosine; Animals; Auditory Pathways; Baclofen; Blotting, Western; Brain Stem; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Neural Inhibition; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Synaptophysin; Tetrodotoxin; Theophylline | 2003 |
Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning.
Topics: Adenosine; Animals; Bradycardia; Chemical Warfare Agents; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Heart Diseases; Hypotension; Injections, Intramuscular; Male; Poisoning; Purinergic P1 Receptor Agonists; Rats; Sarin; Theophylline | 2004 |
Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Methamphetamine; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Xanthines | 2003 |
The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System; Synaptic Transmission; Theobromine; Theophylline; Triazines; Triazoles | 2004 |
Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials, Motor; Female; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Reflex, Monosynaptic; Spinal Cord; Spinal Nerve Roots; Stress, Mechanical; Theophylline | 2004 |
Adenosine A(1)-receptor-mediated tonic inhibition of glutamate release at rat hippocampal CA3-CA1 synapses is primarily due to inhibition of N-type Ca(2+) channels.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; Rats; Rats, Wistar; Receptor, Adenosine A1; Synapses; Synaptic Transmission; Theophylline | 2004 |
Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
Effects of single and long-term theophylline treatment on the threshold of mechanical nociception: contribution of adenosine A1 and alpha2-adrenoceptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analgesics; Animals; Male; Pain Measurement; Pain Threshold; Prazosin; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline | 2005 |
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Angiotensin II; Animals; Arterioles; Feedback; Female; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Purines; Receptor, Adenosine A1; Receptors, Adenosine A2; Theophylline; Triazines; Triazoles; Vasoconstriction; Vasodilation | 2006 |
Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Biomarkers; Cerebral Cortex; Dose-Response Relationship, Drug; Gene Expression Regulation; Limbic System; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Theophylline; Ventral Tegmental Area | 2009 |
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2009 |
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial Infarction; Naloxone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Opioid; Receptors, Purinergic P1; Theophylline; Time Factors | 2012 |
Activation of NTS A(1) adenosine receptors inhibits regional sympathetic responses evoked by activation of cardiopulmonary chemoreflex.
Topics: Adenosine; Animals; Biguanides; Blood Pressure; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Dose-Response Relationship, Drug; Feedback, Physiological; Heart Rate; Lung; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Theophylline | 2012 |