theophylline has been researched along with morphine in 94 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (42.55) | 18.7374 |
| 1990's | 18 (19.15) | 18.2507 |
| 2000's | 21 (22.34) | 29.6817 |
| 2010's | 12 (12.77) | 24.3611 |
| 2020's | 3 (3.19) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Paalzow, G | 1 |
| Ho, IK | 1 |
| Collier, HO; Francis, DL; Roy, AC | 2 |
| Butt, NM; Collier, HO; Cuthbert, NJ; Francis, DL; Saeed, SA | 1 |
| Bhargava, HN; Ho, LK; Loh, HH; Way, EL | 1 |
| Jhamandas, K; Sawynok, J; Sutak, M | 1 |
| Andersson, KE | 2 |
| Larochelle, P; Ogilvie, RI | 1 |
| Knoll, J; Vizi, ES | 1 |
| Burks, TF; Grubb, MN | 1 |
| Jhamandas, KH; Sawynok, J | 1 |
| DeLander, GE; Mosberg, HI; Porreca, F | 1 |
| Calignano, A; Mancuso, F; Persico, P; Sorrentino, L | 1 |
| Sawynok, J; Sweeney, MI; White, TD | 1 |
| Duan, DS; Eiger, S; Lameh, J; Sadée, W; Yu, VC | 1 |
| Ono, H; Vasko, MR | 1 |
| Espey, MJ; Reid, A; Sawynok, J | 1 |
| al-Rafai, S; Bernhardt, A; Kaiser, H; Klimpel, L; Lang, U; Niesel, HC | 1 |
| Lucas, ML; McEwan, GT | 1 |
| Holroyde, MC; Jackson, DM; Leeson, ME; Norris, AA | 1 |
| Dunwiddie, TV; Lupica, CR | 1 |
| Beaumier, P; Fenwick, JD; Kwong, E; Leavitt, R; Mendonca, M; Nespolo, R; Stevenson, AJ; Todi, F; Weber, MP; Young, L | 1 |
| DeLander, GE; Hopkins, CJ | 1 |
| Kleven, MS; Sparber, SB | 1 |
| Ahlijanian, MK; Takemori, AE | 1 |
| Kharin, NA; Komissarov, IV; Serdiuk, SE | 1 |
| Peterson, GR; Shuster, L; Werner, I | 1 |
| Ho, IK; Loh, HH; Way, EL | 2 |
| Castillo, S; Contreras, E; Quijada, L | 1 |
| Collier, HO; Francis, DL; Henderson, G; Schneider, C | 1 |
| Laplace, JP; Ruckebusch, Y | 1 |
| Burgison, RM; Dietz, AJ | 1 |
| Collier, HO; Tucker, JF | 1 |
| Gaion, RM; Trento, M | 1 |
| Sedman, AJ | 1 |
| Beubler, E | 1 |
| Beubler, E; Lembeck, F | 1 |
| Kienlen, J | 1 |
| Elliott, J; Jhamandas, K; Notman, H; Sutak, M | 1 |
| Contreras, E; Juica, S; Tamayo, L | 1 |
| Badawy, AA; Morgan, CJ | 1 |
| Stone, TW | 1 |
| Brailowsky, S; Guerrero-Muñoz, F; Luján, M; Shkurovich, M | 1 |
| Clement, JG; Gallant, CA | 1 |
| Magyar, K; Somogyi, GT; Vizi, ES | 1 |
| Nikfar, S; Zarrindast, MR | 1 |
| Graham, NB; McNeill, ME | 1 |
| Hope, W; Rose'Meyer, RB; White, PJ | 1 |
| Ansell, RJ; Mosbach, K; Ramström, O | 1 |
| Blaho, K; Merigian, K | 1 |
| Forró, G; Pap, A | 1 |
| Jarvis, MF; Kowaluk, EA; Lynch, JJ | 1 |
| Hasegawa, T; Itoh, A; Mamiya, T; Nabeshima, T; Nakayama, S; Noda, Y; Shiotani, T | 1 |
| Gouardères, C; Jhamandas, K; Sutak, M; Zajac, JM | 1 |
| Woodside, JR | 1 |
| Fathollahi, Y; Khalili, M; Semnanian, S | 1 |
| Homayoun, H; Khavandgar, S; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Epstein, OI; Ratushnyak, AS; Shtark, MB; Simonova, OG; Zapara, TA | 1 |
| DELPHAUT, J; LANZA, M; SARLES, H | 1 |
| AUROUSSEAU, M; BATHELLIER, C; KORNOWSKI, H; PESSON, M | 1 |
| Sitar, DS | 1 |
| Barzegari, AA; Ghoshooni, H; Haeri-Rohani, A; Sahraei, H; Salimi, SH; Sepehri, H; Shams, J; Zarrindast, MR | 1 |
| Jhamandas, K; McNaull, B; Sutak, M; Trang, T | 1 |
| Bonnaire, Y; Julliand, V; Lallemand, A; Respondek, F | 1 |
| Fan, W; Kaplan, GB; Klufas, MA; Leite-Morris, KA | 1 |
| Capasso, A; Gallo, C | 1 |
| Goineau, S; Guillaume, P; Picard, S; Rompion, S | 1 |
| Berdeaux, A; Chenoune, M; Cohen, MV; Darbera, L; Downey, JM; Ghaleh, B; Lidouren, F; Tissier, R | 1 |
| Kleine-Brüggeney, M; Kranke, P; Stamer, UM | 1 |
| Radke, K; Radke, OC | 1 |
| Roche, N | 1 |
| Aminyavari, S; Asgari Taei, A; Farahmandfar, M; Naghizadeh, A; Riahi, E; Saberian, H; Torkaman-Boutorabi, A | 1 |
| Dousti Kataj, P; Ghaffari, K; Torkaman-Boutorabi, A; Vousooghi, N | 1 |
8 review(s) available for theophylline and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Opiates, cyclic nucleotides, and xanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Behavior, Animal; Brain; Caffeine; Cyclic AMP; Dopamine; Enzyme Activation; Humans; Lung; Morphine; Narcotics; Prostaglandins E; Theophylline; Xanthines | 1976 |
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
Cimetidine-drug interactions.
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Chlormethiazole; Cimetidine; Drug Interactions; Humans; Ketoconazole; Kidney; Lidocaine; Morphine; Penicillins; Theophylline | 1984 |
[Effects of acidosis on the action of drugs used in anesthesia and intensive care].
Topics: Acidosis; Anesthetics; Anesthetics, Local; Carrier Proteins; Catecholamines; Critical Care; Heparin; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Morphine; Muscle Relaxants, Central; Narcotics; Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Theophylline | 1983 |
[Prophylaxis and therapy of postdural puncture headache--a critical evaluation of treatment options].
Topics: Adrenocorticotropic Hormone; Adult; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Patch, Epidural; Caffeine; Central Nervous System Stimulants; Diagnosis, Differential; Dura Mater; Female; Humans; Injections, Spinal; Morphine; Post-Dural Puncture Headache; Pregnancy; Serotonin Antagonists; Theophylline; Vasodilator Agents | 2011 |
[Post-dural puncture headache].
Topics: Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Blood Patch, Epidural; Caffeine; Central Nervous System Stimulants; Diagnosis, Differential; Dura Mater; Humans; Morphine; Needles; Post-Dural Puncture Headache; Theophylline; Vasodilator Agents | 2013 |
Systemic Medications in Chronic Obstructive Pulmonary Disease: Use and Outcomes.
Topics: Administration, Oral; Adrenal Cortex Hormones; alpha 1-Antitrypsin; Animals; Azithromycin; Humans; Macrolides; Morphine; Oxidative Stress; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Theophylline; Treatment Outcome; Xanthines | 2021 |
1 trial(s) available for theophylline and morphine
| Article | Year |
|---|---|
Urinary excretion of dietary contaminants in horses.
Topics: Animals; Atropine; Bufotenin; Caffeine; Cross-Over Studies; Doping in Sports; Dose-Response Relationship, Drug; Food Contamination; Horses; Morphine; N,N-Dimethyltryptamine; Physical Conditioning, Animal; Scopolamine; Theobromine; Theophylline | 2006 |
85 other study(ies) available for theophylline and morphine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Naloxone antagonizes theophylline-induced potentiation of morphine inhibition of a nociceptive reaction in rats.
Topics: Analgesics; Animals; Drug Interactions; Electric Stimulation; Male; Morphine; Naloxone; Pimozide; Rats; Theophylline; Time Factors; Vocalization, Animal | 1979 |
Effect of pharmacological manipulation on pentobarbital response.
Topics: Aminooxyacetic Acid; Animals; Drug Interactions; Fenclonine; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Morphine; Pargyline; Pentobarbital; Sleep; Theophylline; Time Factors; Tremorine | 1975 |
Morphone abstinence and quasi-abstinence effects after phosphodiesterase inhibitors and naloxone.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Morphine; Naloxone; Phosphodiesterase Inhibitors; Prostaglandins; Rats; Structure-Activity Relationship; Substance Withdrawal Syndrome; Theophylline; Time Factors; Xanthines | 1975 |
Mechanism of quasi-morphine withdrawal behaviour induced by methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Humans; Male; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Theobromine; Theophylline; Xanthines | 1979 |
Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Cyclic GMP; Cycloheximide; Drug Tolerance; Humans; Mice; Morphine; Naloxone; Phosphodiesterase Inhibitors; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline | 1975 |
Antagonism of morphine action on brain acetylcholine release by methylxanthines and calcium.
Topics: Acetylcholine; Animals; Brain; Caffeine; Calcium; Chlorpromazine; Morphine; Rats; Theophylline; Xanthines | 1978 |
[Conventional treatment of left ventricular failure in relation to modern pharmacologic possibilities].
Topics: Digitalis Glycosides; Diuretics; Heart Failure; Humans; Morphine; Theophylline | 1978 |
Effect of drugs on effective vascular compliance in acute heart failure.
Topics: Acute Disease; Animals; Aorta, Thoracic; Coronary Vessels; Dogs; Ethacrynic Acid; Heart Failure; Male; Morphine; Nitroglycerin; Pharmacology; Phenoxybenzamine; Theophylline | 1975 |
The inhibitory effect of adenosine and related nucleotides on the release of acetylcholine.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Cholecystokinin; Electric Stimulation; Guinea Pigs; Ileum; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Ouabain; Rats; Theophylline; Xylazine | 1976 |
Selective antagonism of the intesinal stimulatory effects of morphine by isoproterenol prostalglandin E1 and theophylline.
Topics: Acetylcholine; Animals; Depression, Chemical; Dogs; Female; In Vitro Techniques; Intestines; Isoproterenol; Male; Methoxamine; Morphine; Muscle Contraction; Norepinephrine; Prostaglandins E; Stimulation, Chemical; Theophylline | 1975 |
Inhibition of acetylcholine release from cholinergic nerves by adenosine, adenine nucleotides and morphine: antagonism by theophylline.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Male; Morphine; Muscle Contraction; Neurons; Parasympathetic Nervous System; Theophylline | 1976 |
Involvement of adenosine in antinociception produced by spinal or supraspinal receptor-selective opioid agonists: dissociation from gastrointestinal effects in mice.
Topics: Adenosine; Analgesia; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastric Emptying; Gastrointestinal Motility; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Opioid; Spinal Cord; Theophylline | 1992 |
Adenosine release in morphine-induced hypotension in rats.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Blood Pressure; Dipyridamole; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Male; Morphine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Tetrabenazine; Theophylline | 1992 |
Intracerebroventricular morphine releases adenosine and adenosine 3',5'-cyclic monophosphate from the spinal cord via a serotonergic mechanism.
Topics: Adenosine; Animals; Cyclic AMP; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Neurotoxins; Nociceptors; Purinergic Antagonists; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Theophylline | 1991 |
Regulation of cyclic AMP by the mu-opioid receptor in human neuroblastoma SH-SY5Y cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Kinetics; Morphine; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Theophylline; Vasoactive Intestinal Peptide | 1990 |
Adenosine analogs do not inhibit the potassium-stimulated release of substance P from rat spinal cord slices.
Topics: Adenosine; Animals; In Vitro Techniques; Male; Morphine; Neurons, Afferent; Neurotransmitter Agents; Potassium; Potassium Chloride; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Theophylline | 1990 |
8-Phenyltheophylline reverses the antinociceptive action of morphine in the periaqueductal gray.
Topics: 5,7-Dihydroxytryptamine; Adenosine; Analgesia; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Injections, Spinal; Male; Morphine; Norepinephrine; Oxidopamine; Periaqueductal Gray; Rats; Rats, Inbred Strains; Spinal Cord; Theophylline | 1991 |
[Epidural blockade for analgesia and treatment of acute pancreatitis].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Cholangiopancreatography, Endoscopic Retrograde; Dihydroergotamine; Drug Combinations; Humans; Hypotension; Middle Aged; Morphine; Pancreatitis; Prospective Studies; Respiration, Artificial; Theophylline | 1991 |
The effect of E. coli STa enterotoxin on the absorption of weakly dissociable drugs from rat proximal jejunum in vivo.
Topics: Amphetamine; Animals; Bacterial Toxins; Colforsin; Electrolytes; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Lidocaine; Male; Morphine; Perfusion; Phenytoin; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Theophylline | 1990 |
Modulation of neurogenic inflammation in rat trachea.
Topics: Albuterol; Animals; Cromolyn Sodium; Dexamethasone; Electric Stimulation; Inflammation; Male; Methysergide; Morphine; Rats; Theophylline; Thiorphan; Trachea; Vagus Nerve | 1990 |
Release of endogenous adenosine does not mediate electrophysiological responses to morphine in the hippocampus in vitro.
Topics: Adenosine; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Morphine; Rats; Rats, Inbred Strains; Synapses; Theophylline; Time Factors | 1990 |
The influence of furosemide on plasma elimination and urinary excretion of drugs in standardbred horses.
Topics: Acepromazine; Animals; Clenbuterol; Clonixin; Codeine; Drug Interactions; Female; Fentanyl; Furosemide; Horses; Injections, Intravenous; Morphine; Pentazocine; Phenylbutazone; Physical Exertion; Premedication; Theophylline | 1990 |
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines | 1986 |
Morphine blocks and naloxone enhances suppression of operant behavior by low doses of 3-isobutyl-1-methylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Body Temperature; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Theophylline | 1989 |
Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Nalorphine; Norepinephrine; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
[Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig].
Topics: Adenosine; Animals; Baclofen; Clonidine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Myenteric Plexus; Receptors, Cholinergic; Receptors, Neurotransmitter; Theophylline | 1987 |
Choline acetyltransferase and acetylcholinesterase in cultured brain cells from chick embryos.
Topics: Acetylcholinesterase; Acyltransferases; Ammonia; Animals; Brain; Centrifugation; Chick Embryo; Cocaine; Creatine Kinase; Culture Techniques; Cyclic AMP; DNA; Fluorouracil; Histocytochemistry; Microscopy, Phase-Contrast; Morphine; Nerve Tissue Proteins; Spectrophotometry; Theophylline; Thyroxine | 1971 |
Effect of cyclic AMP on morphine analgesia tolerance and physical dependence.
Topics: Analgesia; Animals; Cyclic AMP; Drug Tolerance; Humans; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome; Theophylline | 1972 |
Cyclic adenosine monophosphate antagonism of morphine analgesia.
Topics: Adenylyl Cyclases; Analgesia; Animals; Brain; Cyclic AMP; Dihydroxyphenylalanine; Drug Interactions; Drug Tolerance; Male; Mice; Mice, Inbred ICR; Morphine; Pargyline; Serine; Theophylline; Time Factors; Tryptophan | 1973 |
Effect of drugs that modify 3',5'-AMP concentrations on morphine analgesia.
Topics: Analgesia; Animals; Cyclic AMP; Drug Synergism; Female; Fluorides; Imidazoles; Mice; Morphine; Propranolol; Sodium Chloride; Theophylline | 1972 |
Quasi morphine-abstinence syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; Drug Synergism; Heroin; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Rats; Substance Withdrawal Syndrome; Theophylline | 1974 |
[Pharmacologic changes in feeding behavior: food intake and rumination in sheep].
Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Cerebral Cortex; Chlorpromazine; Digestion; Digitalis Glycosides; Eating; Imipramine; Iproniazid; Lanatosides; Mescaline; Methylphenidate; Morphine; Ouabain; Pentobarbital; Psychopharmacology; Reticulum; Rumen; Sheep; Theophylline | 1968 |
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium.
Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental | 1968 |
The role of adrenergic, purinergic and opiate receptors in the control of prostacyclin-induced contraction in the guinea-pig ileum.
Topics: Animals; Epoprostenol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Phenylisopropyladenosine; Receptors, Adrenergic; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Purinergic; Theophylline | 1984 |
Pharmacological aspects on the treatment of CHF.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Cardiac Glycosides; Diuretics; Heart Failure; Heart Rate; Hemodynamics; Humans; Morphine; Myocardial Contraction; Theophylline; Vasodilator Agents | 1981 |
Influence of vasoactive intestinal polypeptide on net water flux and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum.
Topics: Adenylyl Cyclases; Animals; Atropine; Body Water; Cyclic AMP; Female; Gastrointestinal Hormones; Jejunum; Morphine; Rats; Theophylline; Vasoactive Intestinal Peptide | 1980 |
Inhibition by morphine of prostaglandin E1-stimulated secretion and cyclic adenosine 3',5'-monophosphate formation in the rat jejunum in vivo.
Topics: Alprostadil; Animals; Antidiarrheals; Body Water; Cyclic AMP; Female; Intestinal Secretions; Jejunum; Morphine; Naloxone; Prostaglandins E; Rats; Rats, Inbred Strains; Theophylline | 1980 |
Antagonism of enkephalin action on acetylcholine release by methylxanthines: lack of a purine link.
Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Enkephalins; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Rats; Theophylline; Xanthines | 1983 |
Sensitivity changes after morphine treatment in the mouse uterus.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Drug Tolerance; Female; In Vitro Techniques; Mice; Morphine; Naloxone; Serotonin; Theophylline; Uterine Contraction | 1982 |
Tryptophan and tryptophan pyrrolase in haem regulation. The role of lipolysis and direct displacement of serum-protein-bound tryptophan in the opposite effects of administration of endotoxin, morphine, palmitate, salicylate and theophylline on rat liver 5
Topics: 5-Aminolevulinate Synthetase; Animals; Carboxylic Acids; Endotoxins; Heme; Lipolysis; Lipopolysaccharides; Liver; Male; Morphine; Rats; Rats, Inbred Strains; Theophylline; Tryptophan; Tryptophan Oxygenase | 1982 |
Theophylline does not affect morphine inhibition of the isolated vas deferens.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Morphine; Theophylline; Vas Deferens | 1981 |
Morphine-theophylline interaction: antagonism or facilitation?
Topics: Animals; Calcium; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Lethal Dose 50; Mice; Morphine; Motor Activity; Naloxone; Synaptosomes; Theophylline | 1981 |
Methylxanthines antagonize adenosine but not morphine inhibition in guinea pig ileum.
Topics: Adenosine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Theophylline; Xanthines | 1981 |
Evidence that morphine and opioid peptides do not share a common pathway with adenosine in inhibiting acetylcholine release from isolated intestine.
Topics: Acetylcholine; Adenosine; Animals; Electric Stimulation; Endorphins; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Intestines; Morphine; Muscle, Smooth; Myenteric Plexus; Theophylline | 1981 |
Different influences of adenosine receptor agonists and antagonists on morphine antinociception in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dipyridamole; Dose-Response Relationship, Drug; Male; Mice; Morphine; Nociceptors; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Tail; Theophylline | 1994 |
Properties controlling the diffusion and release of water-soluble solutes from poly(ethylene oxide) hydrogels. 1. Polymer composition.
Topics: Aminophylline; Biocompatible Materials; Caffeine; Diffusion; Drug Carriers; Drug Delivery Systems; Gels; Models, Chemical; Morphine; Polyethylene Glycols; Polyurethanes; Solubility; Theophylline; Water | 1993 |
The role of adenosine in the hypotensive actions of morphine.
Topics: Adenosine; Animals; Blood Pressure; Female; Guanethidine; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1995 |
Towards artificial antibodies prepared by molecular imprinting.
Topics: Antibodies; Atrazine; Binding, Competitive; Corticosterone; Cross Reactions; Diazepam; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocortisone; Kinetics; Methylglucosides; Molecular Mimicry; Morphine; Polymers; Propranolol; Radioimmunoassay; Stereoisomerism; Theophylline; Yohimbine | 1996 |
The role of pharmacology and forensics in the death of an asthmatic.
Topics: Administration, Inhalation; Adult; Albuterol; Asthma; Fatal Outcome; Heroin; Humans; Lung; Male; Morphine; Pulmonary Edema; Rhinitis, Allergic, Perennial; Substance-Related Disorders; Theophylline | 1995 |
[The effect of theophylline preparations on morphine-induced spasm of Oddi's sphincter in man].
Topics: Adult; Aged; Aminophylline; Analgesics, Opioid; Cardiotonic Agents; Female; Humans; Male; Middle Aged; Morphine; Spasm; Sphincter of Oddi; Theophylline | 1998 |
An adenosine kinase inhibitor attenuates tactile allodynia in a rat model of diabetic neuropathic pain.
Topics: Adenosine Kinase; Animals; Anti-Bacterial Agents; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Morphine; Narcotics; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Streptozocin; Theophylline; Tubercidin | 1999 |
Attenuation of the development of morphine dependence/tolerance by nefiracetam: involvement of adenosine 3':5'-cyclic monophosphate system.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Cyclic AMP; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Phosphodiesterase Inhibitors; Psychotropic Drugs; Pyrrolidinones; Substance Withdrawal Syndrome; Theophylline; Xanthines | 2000 |
Role of adenosine in the spinal antinociceptive and morphine modulatory actions of neuropeptide FF analogs.
Topics: Adenosine; Analgesics, Opioid; Animals; Male; Morphine; Oligopeptides; Rats; Rats, Sprague-Dawley; Spinal Cord; Theophylline | 2000 |
Female smokers have increased postoperative narcotic requirements.
Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Gynecologic Surgical Procedures; Humans; Medical Records; Morphine; Nicotine; Pain, Postoperative; Postoperative Care; Retrospective Studies; Smoking; Smoking Cessation; Theophylline; Therapeutic Equivalency | 2000 |
Caffeine increases paragigantocellularis neuronal firing rate and induces withdrawal signs in morphine-dependent rats.
Topics: Adenosine; Analgesics, Opioid; Animals; Caffeine; Electrophysiology; Male; Medulla Oblongata; Microinjections; Morphine; Morphine Dependence; Neurons; Purinergic P1 Receptor Agonists; Rats; Substance Withdrawal Syndrome; Theophylline | 2001 |
The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics, Opioid; Animals; Learning; Male; Memory; Mice; Morphine; Receptors, Purinergic P1; Theophylline; Vasodilator Agents | 2002 |
Reaction of neurons to alkaloid agonists of opioid receptors during modulation of phosphodiesterases.
Topics: Alkaloids; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Lymnaea; Membrane Potentials; Models, Biological; Morphine; Neurons; Phosphoric Diester Hydrolases; Receptors, Opioid; Signal Transduction; Theophylline | 2003 |
[Effect of morphine, papaverine, theophylline and khellin on biliary manometric tests in the dog under chloralose sedation].
Topics: Anesthesia; Animals; Biliary Tract; Chloralose; Dogs; Humans; Khellin; Manometry; Morphine; Papaverine; Theophylline | 1956 |
[CHEMICAL AND PHARMACODYNAMIC STUDY OF 8-PIPERIDYLTHEOPHYLLINES].
Topics: Acetylcholine; Animals; Barium; Blood Pressure; Chlorides; Diuresis; Dogs; Duodenum; Heart; Mice; Morphine; Muscle Relaxants, Central; Muscle, Smooth; Pharmacology; Piperidines; Rabbits; Rats; Research; Respiration; Theophylline | 1964 |
Old drugs - old people - new insights.
Topics: Aging; Humans; Morphine; Pharmaceutical Preparations; Pharmacology, Clinical; Propylthiouracil; Theophylline | 2005 |
Theophylline inhibits tolerance and sensitization induced by morphine: a conditioned place preference paradigm study in female mice.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Female; Mice; Morphine; Narcotics; Phosphodiesterase Inhibitors; Reinforcement, Psychology; Theophylline | 2006 |
Inhibition of tolerance to spinal morphine antinociception by low doses of opioid receptor antagonists.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Hyperalgesia; Injections, Spinal; Male; Morphine; Naltrexone; Narcotic Antagonists; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Somatostatin; Theophylline | 2007 |
Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Biomarkers; Cerebral Cortex; Dose-Response Relationship, Drug; Gene Expression Regulation; Limbic System; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Theophylline; Ventral Tegmental Area | 2009 |
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2009 |
Ventilatory function assessment in safety pharmacology: optimization of rodent studies using normocapnic or hypercapnic conditions.
Topics: Animals; Guinea Pigs; Hypercapnia; Male; Mice; Mice, Inbred BALB C; Models, Animal; Morphine; Pharmacology; Plethysmography, Whole Body; Rats; Rats, Wistar; Respiratory Physiological Phenomena; Species Specificity; Theophylline | 2010 |
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial Infarction; Naloxone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Opioid; Receptors, Purinergic P1; Theophylline; Time Factors | 2012 |
Effect of histone acetylation on maintenance and reinstatement of morphine-induced conditioned place preference and ΔFosB expression in the nucleus accumbens and prefrontal cortex of male rats.
Topics: Acetylation; Animals; Behavior, Animal; Conditioning, Classical; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Male; Morphine; Narcotics; Nucleus Accumbens; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Theophylline; Vorinostat | 2021 |
Pre-mating administration of theophylline could prevent the transgenerational effects of maternal morphine dependence on offspring anxiety behavior: The role of dopamine receptors.
Topics: Animals; Anxiety; Anxiety Disorders; Female; Male; Morphine; Morphine Dependence; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Theophylline | 2023 |