theophylline and montelukast

theophylline has been researched along with montelukast in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.45)18.2507
2000's17 (54.84)29.6817
2010's11 (35.48)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bachmann, K; Ebel, D; Huhn, RD; Hunt, TL; Jauregui, L; Larson, P; Malmstrom, K; Miller, K; Peszek, I; Reese, JH; Reiss, TF; Schwartz, J; Scott, M; Shingo, S; Sullivan, TJ1
Szefler, SJ1
Eren, A; Sipit, T; Taci, N; Yurdakul, AS1
Keeley, D; McKean, M1
Shah, AR; Shah, KV; Sharples, LD; Solanki, RN1
Allayee, H; Cohen, RI; Dixon, AE; Holbrook, JT; Irvin, CG; Lima, JJ; Shade, DM; Skloot, GS; Smith, LJ; Wise, RA1
Katsunuma, T; Kondo, N; Morikawa, A; Odajima, Y1
Alluri, R; Currie, GP; Nair, A1
Allayee, H; Conti, DV; Hartiala, J; Irvin, CG; Lee, W; Lima, JJ; Mehrabian, M1
Brantly, ML; Eden, E; Holbrook, JT; Turino, GM; Wise, RA1
Mastronarde, JG; Olopade, CO; Scharf, SM; Shade, DM; Wise, RA1
Kremer, HJ; Lecheler, J; Maus, J; Munzel, U; Nguyen, DT; Petzold, U; Pfannebecker, B1
Ilango, K; Nageswari, AD; Rajanandh, MG2
Camenisch, G; Chibale, K; Huth, F; Njuguna, NM; Schiller, H; Umehara, KI1
Bellon, H; Heigl, T; Hoet, P; Lammertyn, E; Mathyssen, C; Pilette, C; Sacreas, A; Vanaudenaerde, BM; Vandermeulen, E; Verleden, GM; Verleden, SE; Vos, R; Vriens, H1
Al-Huniti, N; Bui, KH; Cheung, SYA; Johnson, TN; Li, J; Xu, H; Zhou, D; Zhou, W1
Athari, SS; Ma, Y; Tu, Y; Yang, XH1

Reviews

3 review(s) available for theophylline and montelukast

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Asthma: the new advances.
    Advances in pediatrics, 2000, Volume: 47

    Topics: Acetates; Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Glucocorticoids; Humans; Leukotriene Antagonists; Pulmonary Ventilation; Quinolines; Risk Factors; Severity of Illness Index; Sulfides; Theophylline

2000
Asthma and other wheezing disorders in infants and children.
    Clinical evidence, 2004, Issue:11

    Topics: Acetates; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Cromolyn Sodium; Cyclopropanes; Drug Therapy, Combination; Humans; Infant; Ipratropium; Nebulizers and Vaporizers; Nedocromil; Quinolines; Respiratory Sounds; Sulfides; Theophylline

2004

Trials

12 trial(s) available for theophylline and montelukast

ArticleYear
Effect of montelukast on single-dose theophylline pharmacokinetics.
    American journal of therapeutics, 1998, Volume: 5, Issue:3

    Topics: Acetates; Administration, Oral; Adult; Anti-Asthmatic Agents; Bronchodilator Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Interactions; Drug Monitoring; Humans; Injections, Intravenous; Leukotriene Antagonists; Male; Quinolines; Sulfides; Theophylline; Time Factors

1998
Comparative efficacy of once-daily therapy with inhaled corticosteroid, leukotriene antagonist or sustained-release theophylline in patients with mild persistent asthma.
    Respiratory medicine, 2003, Volume: 97, Issue:12

    Topics: Acetates; Administration, Inhalation; Adrenergic beta-2 Receptor Antagonists; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Delayed-Action Preparations; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Sulfides; Theophylline; Treatment Outcome

2003
Double-blind, randomised, controlled trial assessing controller medications in asthma.
    Respiration; international review of thoracic diseases, 2006, Volume: 73, Issue:4

    Topics: Acetates; Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Middle Aged; Patient Selection; Quinolines; Sulfides; Theophylline

2006
Effect of obesity on clinical presentation and response to treatment in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2006, Volume: 43, Issue:7

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclopropanes; Cytokines; Disease Progression; Double-Blind Method; Female; Forced Expiratory Volume; Gastroesophageal Reflux; Humans; Male; Middle Aged; Obesity; Quinolines; Risk Factors; Sleep Wake Disorders; Sulfides; Theophylline; Treatment Outcome; Vital Capacity

2006
Clinical trial of low-dose theophylline and montelukast in patients with poorly controlled asthma.
    American journal of respiratory and critical care medicine, 2007, Feb-01, Volume: 175, Issue:3

    Topics: Acetates; Administration, Inhalation; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Flow Rates; Glucocorticoids; Humans; Leukotriene Antagonists; Lung; Male; Middle Aged; Quinolines; Severity of Illness Index; Sulfides; Theophylline; Treatment Outcome

2007
A randomized open-label comparative study of montelukast versus theophylline added to inhaled corticosteroid in asthmatic children.
    Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:3

    Topics: Acetates; Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Delayed-Action Preparations; Female; Humans; Leukotriene Antagonists; Male; Quinolines; Sulfides; Theophylline

2006
The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics.
    Chest, 2007, Volume: 132, Issue:3

    Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Interleukin-6; Lipids; Male; Middle Aged; Quinolines; Risk Factors; Sulfides; Theophylline

2007
Prevalence of alpha-1 antitrypsin deficiency in poorly controlled asthma--results from the ALA-ACRC low-dose theophylline trial.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2007, Volume: 44, Issue:8

    Topics: Acetates; Adolescent; Adult; Aged; alpha 1-Antitrypsin Deficiency; Asthma; Bronchodilator Agents; Cohort Studies; Cyclopropanes; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Phenotype; Prevalence; Quinolines; Statistics, Nonparametric; Sulfides; Theophylline; United States

2007
Sleep quality in asthma: results of a large prospective clinical trial.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2008, Volume: 45, Issue:3

    Topics: Acetates; Adult; Asthma; Bronchodilator Agents; Cyclopropanes; Double-Blind Method; Female; Humans; Leukotriene Antagonists; Male; Quality of Life; Quinolines; Respiratory Function Tests; Sleep Wake Disorders; Sulfides; Surveys and Questionnaires; Theophylline

2008
Prevention of exercise-induced asthma by a fixed combination of disodium cromoglycate plus reproterol compared with montelukast in young patients.
    Arzneimittel-Forschung, 2008, Volume: 58, Issue:6

    Topics: Acetates; Adolescent; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Bronchodilator Agents; Child, Preschool; Cromolyn Sodium; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Combinations; Exercise Test; Female; Forced Expiratory Flow Rates; Humans; Male; Metaproterenol; Quinolines; Sulfides; Theophylline

2008
Pulmonary function assessment in mild to moderate persistent asthma patients receiving montelukast, doxofylline, and tiotropium with budesonide: a randomized controlled study.
    Clinical therapeutics, 2014, Apr-01, Volume: 36, Issue:4

    Topics: Acetates; Adult; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Formoterol Fumarate; Humans; Male; Middle Aged; Quinolines; Respiratory Function Tests; Sulfides; Theophylline; Tiotropium Bromide

2014
Assessment of montelukast, doxofylline, and tiotropium with budesonide for the treatment of asthma: which is the best among the second-line treatment? A randomized trial.
    Clinical therapeutics, 2015, Feb-01, Volume: 37, Issue:2

    Topics: Acetates; Adolescent; Adult; Asthma; Bronchodilator Agents; Budesonide; Cyclopropanes; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Quinolines; Respiratory Function Tests; Sulfides; Theophylline; Tiotropium Bromide

2015

Other Studies

16 other study(ies) available for theophylline and montelukast

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Drugs for asthma.
    The Medical letter on drugs and therapeutics, 1999, Jan-15, Volume: 41, Issue:1044

    Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bone Density; Bronchial Spasm; Bronchodilator Agents; Child; Child, Preschool; Choice Behavior; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth; Humans; Hydroxyurea; Indoles; Infant, Newborn; Ipratropium; Lactation; Leukotriene Antagonists; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Tachycardia; Theophylline; Tosyl Compounds

1999
Drugs for asthma.
    The Medical letter on drugs and therapeutics, 2000, Mar-06, Volume: 42, Issue:1073

    Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Spasm; Child; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth Disorders; Humans; Hydroxyurea; Indoles; Ipratropium; Lactation; Leukotriene Antagonists; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Theophylline; Tosyl Compounds

2000
Montelukast and theophylline: no use or some use in persistent asthma?
    American journal of respiratory and critical care medicine, 2007, May-15, Volume: 175, Issue:10

    Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Humans; Quinolines; Randomized Controlled Trials as Topic; Sulfides; Theophylline

2007
Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction.
    Drug metabolism and personalized therapy, 2016, 12-01, Volume: 31, Issue:4

    Topics: Acetates; Cyclopropanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Ketoconazole; Phenotype; Quinidine; Quinolines; Sulfaphenazole; Sulfides; Theophylline; Ticlopidine

2016
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options.
    Transplant international : official journal of the European Society for Organ Transplantation, 2017, Volume: 30, Issue:4

    Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome

2017
Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.
    Clinical pharmacology and therapeutics, 2018, Volume: 104, Issue:1

    Topics: Acetates; Analgesics, Opioid; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Bronchodilator Agents; Child; Child, Preschool; Cyclopropanes; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diclofenac; Esomeprazole; Histamine H1 Antagonists, Non-Sedating; Humans; Infant; Infant, Newborn; Itraconazole; Lansoprazole; Loratadine; Models, Biological; Ondansetron; Pharmaceutical Preparations; Pharmacokinetics; Proton Pump Inhibitors; Quinolines; Serotonin Antagonists; Sufentanil; Sulfides; Theophylline; Tramadol

2018
Survey the effect of drug treatment on modulation of cytokines gene expression in allergic rhinitis.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Albuterol; Animals; Budesonide; Cytokines; Disease Models, Animal; Gene Expression; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Rhinitis, Allergic; Theophylline

2023