theophylline and methotrexate

theophylline has been researched along with methotrexate in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (20.00)	18.7374
1990's	15 (30.00)	18.2507
2000's	11 (22.00)	29.6817
2010's	14 (28.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bar-Eli, M; Callily, R; Cohen, H; Wahba, A	1
Henderson, GB; Huennekens, FM; Zevely, EM	1
Azizkhan, JC; Speeg, KV; Stromberg, K	1
Alt, FW; Kellems, RE; Morhenn, VB; Pfendt, EA; Schimke, RT	1
Savage, RL	1
Ito, K	1
Szefler, SJ	1
Cochran, JE; Cott, GR; Erzurum, SC; Glynn-Barnhart, AM; Leff, JA; Martin, RJ; Szefler, SJ	2
Guss, S; Portnoy, J	1
Knoblauch, A; Osterwalder, JJ	1
Bradley, CR; Conner, DP; Peck, CC	1
Almirez, RG; Bradley, CR; Conner, DP; Peck, CC; Rhyne, PR	1
Alkaysi, HN; Gharaibeh, AM; Salem, MA	1
Cataldi, TR; Palmisano, F; Zambonin, PG	1
Catovsky, D; Das, KC; Hoffbrand, V; Tripp, E	1
Gewirtz, DA; Goldman, ID; Randolph, JK	1
Johnson, LF; Wiedemann, LM; Wu, JS	1
Bendas, CM; D'Antonio, LE	1
Abbondandolo, A; Bonatti, S; Bozzo, S; Miele, M; Moro, F; Ottaggio, L; Simili, M	1
Coffey, MJ; Eschenbacher, WL; McCune, WJ; Ramesh, S; Sanders, G; Toews, GB; Tsien, A; Weber, RW	1
Diaz, JD; Ledford, DK; Lockey, RF; Seleznick, MJ; Stewart, GE; Trudeau, WL	1
Reisman, JJ	1
Aboleneen, H; Backes, D; Simpson, J	1
Barnes, PJ	1
Cronstein, BN; Desai, A; McCrary, CT; Montesinos, MC; Posadas, I; Yap, JS	1
Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Minamino, T; Mori, H; Node, K; Ogai, A; Ogita, H; Sanada, S; Shinozaki, Y; Takashima, S; Tomoike, H	1
Cronstein, B; Haskó, G	1
Bergdahl, E; Sundqvist, KG; Talme, T	1
Griss, R; Johnsson, K; Schena, A; Xue, L; Yu, Q	1

Reviews

6 review(s) available for theophylline and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drugs and breast milk. Journal of human nutrition, 1977, Volume: 31, Issue:6 Topics: Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticoagulants; Anticonvulsants; Cyclophosphamide; Female; Hormones; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Iodides; Male; Methotrexate; Milk, Human; Narcotics; Pharmaceutical Preparations; Propranolol; Psychotropic Drugs; Sulfonamides; Theophylline; Thiouracil; Tolbutamide	1977
Anti-inflammatory drugs in the treatment of allergic disease. The Medical clinics of North America, 1992, Volume: 76, Issue:4 Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Auranofin; Bronchodilator Agents; Cromolyn Sodium; Drug Therapy, Combination; Glucocorticoids; Humans; Hydroxychloroquine; Immunoglobulins, Intravenous; Methotrexate; Quality of Life; Severity of Illness Index; Steroids; Theophylline; Troleandomycin	1992
Advances in respiratory therapeutics in children. Current opinion in pediatrics, 1993, Volume: 5, Issue:2 Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Inflammatory Agents; Asthma; Bronchiolitis, Viral; Bronchodilator Agents; Budesonide; Child; Cystic Fibrosis; Hemosiderosis; Humans; Infant, Newborn; Lung Diseases; Methotrexate; Pregnenediones; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Theophylline	1993
Immunomodulation as asthma therapy: where do we stand? The European respiratory journal. Supplement, 1996, Volume: 22 Topics: Adjuvants, Immunologic; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Bacterial Agents; Antibodies, Monoclonal; Asthma; Bronchodilator Agents; Cell Adhesion; Cromolyn Sodium; Cyclosporine; Cytokines; Gold; Humans; Immunoglobulin G; Immunosuppressive Agents; Macrolides; Methotrexate; Nedocromil; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Theophylline	1996
Methylxanthines and inflammatory cells. Handbook of experimental pharmacology, 2011, Issue:200 Topics: Animals; Caffeine; Humans; Immune System; Inflammation; Methotrexate; Receptors, Purinergic P1; Theophylline	2011

Trials

4 trial(s) available for theophylline and methotrexate

Article	Year
Effect of low-dose methotrexate on the disposition of glucocorticoids and theophylline. The Journal of allergy and clinical immunology, 1991, Volume: 88, Issue:2 Topics: Adult; Aged; Double-Blind Method; Drug Interactions; Female; Glucocorticoids; Humans; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Theophylline	1991
[Randomized and controlled single-case study--a scientific method for individual and difficult therapy decisions in clinical practice exemplified with methotrexate use in asthma]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1991, Oct-22, Volume: 80, Issue:43 Topics: Adult; Asthma; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Methotrexate; Prednisone; Theophylline	1991
The role of methotrexate in the management of steroid-dependent asthma. Chest, 1994, Volume: 105, Issue:1 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Asthma; Bronchodilator Agents; Double-Blind Method; Forced Expiratory Volume; Humans; Lung; Methotrexate; Middle Aged; Peak Expiratory Flow Rate; Placebos; Prednisone; Prospective Studies; Pulmonary Ventilation; Spirometry; Theophylline; Vital Capacity	1994
Comparison of oral pulse methotrexate with placebo in the treatment of severe glucocorticosteroid-dependent asthma. The Journal of allergy and clinical immunology, 1994, Volume: 94, Issue:3 Pt 1 Topics: Administration, Oral; Adult; Aged; Asthma; Chronic Disease; Double-Blind Method; Drug Tolerance; Female; Forced Expiratory Volume; Humans; Lung; Male; Methotrexate; Middle Aged; Placebos; Prednisone; Theophylline	1994

Other Studies

40 other study(ies) available for theophylline and methotrexate

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Neutrophil chemotaxis in psoriasis. Acta dermato-venereologica, 1979, Volume: 59, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Child; Cyclic AMP; Cyclic GMP; Epidermis; Ethylenediamines; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neutrophils; Phosphodiesterase Inhibitors; Psoriasis; Skin; Theophylline	1979
Cyclic adenosine 3':5'-monophosphate and methotrexate transport in L1210 cells. Cancer research, 1978, Volume: 38, Issue:3 Topics: Animals; Azides; Biological Transport, Active; Cells, Cultured; Cyclic AMP; Glucose; Leukemia L1210; Methotrexate; Prostaglandins E; Theophylline; Xanthines	1978
Isolation of function human trophoblast cells and their partial characterization in primary cell culture. In vitro, 1978, Volume: 14, Issue:7 Topics: Cell Line; Cell Separation; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Humans; Methotrexate; Theophylline; Trophoblasts	1978
Polyoma virus and cyclic AMP-mediated control of dihydrofolate reductase mRNA abundance in methotrexate-resistant mouse fibroblasts. The Journal of biological chemistry, 1979, Jan-25, Volume: 254, Issue:2 Topics: Bucladesine; Cell Line; Cell Transformation, Viral; Culture Media; Cyclic AMP; Drug Resistance; Kinetics; Methotrexate; Polyomavirus; Prostaglandins E; Protein Biosynthesis; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Theophylline	1979
[Current concept on therapy of asthma and pollenosis]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Mar-10, Volume: 81, Issue:3 Topics: Adrenergic beta-Agonists; Allergens; Animals; Asthma; Bronchial Provocation Tests; Desensitization, Immunologic; Humans; Methotrexate; Mites; Parasympatholytics; Pollen; Rhinitis, Allergic, Seasonal; Theophylline	1992
Pharmacokinetics of low-dose methotrexate in adult asthmatics. Pharmacotherapy, 1992, Volume: 12, Issue:5 Topics: Adolescent; Adult; Aged; Asthma; Drug Administration Schedule; Female; Half-Life; Humans; Injections, Intramuscular; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Theophylline	1992
Methotrexate treatment of severe asthma in children. Pediatrics, 1992, Volume: 89, Issue:4 Pt 1 Topics: Adolescent; Albuterol; Asthma; Beclomethasone; Body Height; Body Weight; Child; Child, Preschool; Cromolyn Sodium; Female; Forced Expiratory Volume; Humans; Male; Maximal Expiratory Flow Rate; Methotrexate; Prednisone; Spirometry; Theophylline; Vital Capacity	1992
Noninvasive transdermal chemical collection. I. In vitro adsorption characteristics of gel/charcoal matrices. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1990, Volume: 3, Issue:4 Topics: Absorption; Charcoal; Gels; Methotrexate; Pharmacology; Polyvinyl Alcohol; Povidone; Skin; Theophylline	1990
Noninvasive transdermal chemical collection. II. In vitro and in vivo skin permeability studies. Skin pharmacology : the official journal of the Skin Pharmacology Society, 1990, Volume: 3, Issue:4 Topics: Animals; Charcoal; Gels; Humans; Methotrexate; Parathion; Permeability; Pharmacology; Rats; Skin; Solubility; Theophylline	1990
High-performance liquid chromatographic determination of methotrexate in plasma. Therapeutic drug monitoring, 1990, Volume: 12, Issue:2 Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Methotrexate; Spectrophotometry, Ultraviolet; Theophylline	1990
Determination of the antineoplastic agent methotrexate in body fluids by high-performance liquid chromatography with electrochemical detection. Journal of chromatography, 1985, Nov-08, Volume: 344 Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Indicators and Reagents; Methotrexate; Polarography; Theophylline	1985
Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis. British journal of haematology, 1973, Volume: 25, Issue:4 Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Culture Techniques; Cyclic AMP; Dactinomycin; Deoxyuridine; DNA; Folic Acid; Humans; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; Mitosis; Phosphodiesterase Inhibitors; Puromycin; RNA; Theophylline; Thymidine; Tritium	1973
Efflux in isolated hepatocytes as a possible correlate of secretion in vivo: induced exit of the folic acid analog methotrexate, by dibutyryl cyclic AMP or isobutyl methyl xanthine. Biochemical and biophysical research communications, 1981, Jul-30, Volume: 101, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Bucladesine; In Vitro Techniques; Kinetics; Liver; Male; Methotrexate; Rats; Theophylline	1981
Inhibition of dihydrofolate reductase gene expression following serum withdrawal or db-cAMP addition in methotrexate-resistant mouse fibroblasts. Experimental cell research, 1982, Volume: 141, Issue:1 Topics: Animals; Blood; Bucladesine; Cell Line; DNA; Gene Expression Regulation; Interphase; Kinetics; Methotrexate; Mice; Polyribosomes; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Theophylline	1982
Enhancement of methotrexate activity by theophylline in HeLa cell cultures. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1981, Volume: 168, Issue:1 Topics: Cell Division; Cell Survival; HeLa Cells; Humans; Methotrexate; Theophylline	1981
p53 expression in normal versus transformed mammalian cells. Carcinogenesis, 1995, Volume: 16, Issue:10 Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Aspartic Acid; Burkitt Lymphoma; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; CHO Cells; Cholera Toxin; Cricetinae; Drug Resistance; Embryo, Mammalian; Gene Expression; Genes, p53; Humans; Immunohistochemistry; L Cells; Lymphocytes; Methotrexate; Mice; Phosphonoacetic Acid; Reference Values; Theophylline; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1995
Determination of methotrexate in serum by high-performance liquid chromatography. Journal of chromatography. B, Biomedical applications, 1996, Jun-07, Volume: 681, Issue:2 Topics: Acetonitriles; Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Humans; Methotrexate; Sensitivity and Specificity; Theophylline	1996
Reversal of the antiinflammatory effects of methotrexate by the nonselective adenosine receptor antagonists theophylline and caffeine: evidence that the antiinflammatory effects of methotrexate are mediated via multiple adenosine receptors in rat adjuvant Arthritis and rheumatism, 2000, Volume: 43, Issue:3 Topics: Animals; Ankle Joint; Anti-Inflammatory Agents; Arthritis, Experimental; Arthrography; Caffeine; Female; Methotrexate; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred Lew; Theophylline	2000
Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts. Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:4 Topics: 2-Aminoadipic Acid; Adenosine; Animals; Cardiotonic Agents; Dogs; Methotrexate; Myocardial Infarction; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline	2004
Methotrexate and its therapeutic antagonists caffeine and theophylline, target a motogenic T-cell mechanism driven by thrombospondin-1 (TSP-1). European journal of immunology, 2016, Volume: 46, Issue:5 Topics: Caffeine; Cytokines; Gene Expression Regulation; Gene Silencing; Humans; Immunosuppressive Agents; Low Density Lipoprotein Receptor-Related Protein-1; Methotrexate; Mitogens; RNA, Small Interfering; T-Lymphocytes; Theophylline; Thrombospondin 1	2016
Bioluminescent Antibodies for Point-of-Care Diagnostics. Angewandte Chemie (International ed. in English), 2017, 06-12, Volume: 56, Issue:25 Topics: Antibodies; Biosensing Techniques; Complementarity Determining Regions; Energy Transfer; Humans; Immunoassay; Luminescent Measurements; Luminescent Proteins; Methotrexate; Point-of-Care Systems; Quinine; Reproducibility of Results; Theophylline	2017