theophylline and lomefloxacin

theophylline has been researched along with lomefloxacin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chen, J; Chen, X; Huang, L; Li, X; Sun, Y1
Huang, L; Li, X; Meng, F; Miao, H; Sun, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bai, P; Chen, C; Hu, K; Li, T; Liu, W; Ma, Q; Pan, W; Peng, K; Sang, Z; Yu, L; Zhang, X1
Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL1
An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T1
Healy, DP; Polk, RE; Schoenle, JR; Stotka, J1
Cornel, JH; Martea, M; Vree, TB; Wijnands, GJ1
Atkinson, HC; Begg, EJ; Frampton, CM; Robson, RA; Saunders, DA1
LeBel, M; St-Laurent, M; Vallée, F1
Apichartpichean, R; Hasegawa, T; Kuzuya, T; Muraoka, I; Nadai, M; Takagi, K1
Nix, DE; Norman, A; Schentag, JJ1
Fuhr, U; Harder, S; Staib, AH; Wack, C1
Cantoni, V; Melani, AS; Pirrelli, M; Sarlo, F1

Reviews

1 review(s) available for theophylline and lomefloxacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for theophylline and lomefloxacin

ArticleYear
Lack of interaction between lomefloxacin and caffeine in normal volunteers.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4

    Topics: 4-Quinolones; Adult; Anti-Infective Agents; Caffeine; Double-Blind Method; Drug Interactions; Fluoroquinolones; Half-Life; Humans; Male; Quinolones; Theophylline

1991
Comparative effects of ciprofloxacin and lomefloxacin on the oxidative metabolism of theophylline.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:4

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Drug Interactions; Fluoroquinolones; Humans; Male; Oxidation-Reduction; Quinolones; Random Allocation; Theophylline

1990

Other Studies

13 other study(ies) available for theophylline and lomefloxacin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine

2013
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Inhibitory Concentration 50; Ligands; Peptide Fragments; Permeability; Protein Aggregates

2014
Design, synthesis and evaluation of novel ferulic acid-memoquin hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2016, 05-15, Volume: 26, Issue:10

    Topics: Alkanes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Coumaric Acids; Drug Design; Drug Evaluation, Preclinical; Ethylamines; Humans; Hydrogen Peroxide; Neuroprotective Agents; PC12 Cells; Rats

2016
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species

2017
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram

2019
The effect of multiple-dose oral lomefloxacin on theophylline metabolism in man.
    Chest, 1990, Volume: 98, Issue:6

    Topics: 4-Quinolones; Administration, Oral; Adult; Anti-Infective Agents; Drug Administration Schedule; Drug Interactions; Female; Fluoroquinolones; Humans; Injections, Intravenous; Kidney; Male; Quinolones; Theophylline

1990
Influence of lomefloxacin on the pharmacokinetics of theophylline.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:6

    Topics: 4-Quinolones; Adult; Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Humans; Male; Metabolic Clearance Rate; Quinolones; Theophylline

1990
Kinetic interaction between theophylline and a newly developed quinolone, NY-198.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:7

    Topics: 4-Quinolones; Adult; Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Humans; Male; Quinolones; Theophylline

1989
Effect of lomefloxacin on theophylline pharmacokinetics.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:7

    Topics: 4-Quinolones; Adult; Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Half-Life; Humans; Immunoenzyme Techniques; Male; Quinolones; Theophylline

1989
Interaction of quinolones with the theophylline metabolism in man: investigations with lomefloxacin and pipemidic acid.
    International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:6

    Topics: 4-Quinolones; Adult; Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Interactions; Fluoroquinolones; Humans; Male; Nicotinic Acids; Pipemidic Acid; Quinolines; Quinolones; Theophylline

1989
Safety and effectiveness of lomefloxacin in patients with acute exacerbation of chronic bronchitis (AECB) chronically treated with oral theophyllines.
    Journal of chemotherapy (Florence, Italy), 2001, Volume: 13, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Infective Agents; Bronchitis; Cross-Sectional Studies; Female; Fluoroquinolones; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Theophylline

2001