theophylline and isoniazid

theophylline has been researched along with isoniazid in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (24.32)	18.7374
1990's	10 (27.03)	18.2507
2000's	7 (18.92)	29.6817
2010's	11 (29.73)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Bleyer, H; Franke, G; Siegmund, W; Walter, R; Zeruesenay, D; Zschiesche, M	1
Desta, Z; Steingruber, M	1
Iwainsky, H; Wiesner, B; Winsel, K	1
Self, TH; Thompson, JR	1
Santoso, B	1
Cabezas, R; Izquierdo, I; Jané, F; Torrent, J	1
Harman, EM	1
Dal Negro, R; De Conti, F; Trevisan, F; Turco, P	1
Höglund, P; Nilsson, LG; Paulsen, O	1
Buselmaier, W; Propping, P; Röhrborn, G	1
Williams, MH	1
Fabro, S; Sieber, SM	1
Bachrach, SJ; Karp, RJ; Moskowitz, S	1
Jang, IJ; Kim, SW; Lee, KH; Lee, SH; Lee, SW; Oh, SJ; Shin, SG; Yim, DS	1
Benowitz, NL; Blanc, PD; Dyer, JE; Kearney, TE; Olson, KR	1
Delanty, N; French, JA; Vaughan, CJ	1
Bonner, AB; Peterson, SL; Weir, MR	1
Hahn, IH; Varney, S	1
Ahn, HC; Lee, YC	1
BESSON, H; DEBAY, A	1
Lee, JH; Lee, MG; Yang, KH	1
Churakov, AV; Drozd, KV; Manin, AN; Perlovich, GL	1

Reviews

4 review(s) available for theophylline and isoniazid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Clinical pharmacology in optimization of therapy of lung diseases]. Zeitschrift fur Erkrankungen der Atmungsorgane, 1991, Volume: 177, Issue:1-2 Topics: Antitubercular Agents; Asthma; Biotransformation; Ethionamide; Humans; Isoniazid; Metabolic Clearance Rate; Rifampin; Theophylline; Tuberculosis, Pulmonary	1991
Malnutrition in chronic illness of childhood with special reference to pulmonary disease. Clinics in chest medicine, 1980, Volume: 1, Issue:3 Topics: Child; Chronic Disease; Diet Therapy; Histamine H1 Antagonists; Humans; Isoniazid; Lung Diseases; Nutrition Disorders; Protein-Energy Malnutrition; Risk; Steroids; Theophylline	1980
Medical causes of seizures. Lancet (London, England), 1998, Aug-01, Volume: 352, Issue:9125 Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Bronchodilator Agents; Coma; Confusion; Drug-Related Side Effects and Adverse Reactions; Electroencephalography; Ethanol; Humans; Isoniazid; Multiple Organ Failure; Phenytoin; Seizures; Status Epilepticus; Substance Withdrawal Syndrome; Theophylline; Water-Electrolyte Imbalance	1998

Trials

1 trial(s) available for theophylline and isoniazid

Article	Year
The clearance of theophylline is increased during the initial period of tuberculosis treatment. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2003, Volume: 7, Issue:6 Topics: Adult; Aged; Antitubercular Agents; Bronchodilator Agents; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Theophylline; Time Factors; Tuberculosis, Pulmonary	2003

Article

Year

The clearance of theophylline is increased during the initial period of tuberculosis treatment.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2003, Volume: 7, Issue:6

Topics: Adult; Aged; Antitubercular Agents; Bronchodilator Agents; Drug Interactions; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Theophylline; Time Factors; Tuberculosis, Pulmonary

2003

Other Studies

32 other study(ies) available for theophylline and isoniazid

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Pharmacokinetic interactions between isoniazid and theophylline in rats. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:11 Topics: Animals; Chromatography, High Pressure Liquid; Drug Interactions; Half-Life; Isoniazid; Male; Rats; Rats, Wistar; Theophylline	1992
Pharmacodynamic interactions between isoniazid and theophylline in mice and rats, and the influence of pyridoxine. Die Pharmazie, 1992, Volume: 47, Issue:7 Topics: Animals; Brain; Caffeine; Convulsants; Drug Interactions; Isoniazid; Male; Mice; Pyridoxine; Rats; Rats, Inbred Strains; Theophylline	1992
Theophylline and isoniazid. British journal of clinical pharmacology, 1990, Volume: 30, Issue:6 Topics: Humans; Isoniazid; Male; Metabolic Clearance Rate; Theophylline	1990
Lowering of theophylline clearance by isoniazid in slow and rapid acetylators. British journal of clinical pharmacology, 1990, Volume: 29, Issue:5 Topics: Acetylation; Adult; Half-Life; Humans; Isoniazid; Male; Middle Aged; Phenotype; Theophylline	1990
Theophylline-isoniazid interaction. DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:2 Topics: Adult; Drug Interactions; Female; Humans; Isoniazid; Lung Diseases, Obstructive; Metabolic Clearance Rate; Theophylline; Tuberculosis, Gastrointestinal	1989
Pulmonary problems of pregnancy. Comprehensive therapy, 1985, Volume: 11, Issue:5 Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Drug Therapy, Combination; Ethambutol; Female; Heparin; Humans; Infant, Newborn; Isoniazid; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Infectious; Pulmonary Embolism; Rifampin; Theophylline; Tuberculosis, Pulmonary	1985
Rifampicin-isoniazid and delayed elimination of theophylline: a case report. International journal of clinical pharmacology research, 1988, Volume: 8, Issue:4 Topics: Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Lung Diseases, Obstructive; Male; Middle Aged; Recurrence; Rifampin; Theophylline; Time Factors; Tuberculosis, Pulmonary	1988
Interaction between isoniazid and theophylline. European journal of respiratory diseases, 1987, Volume: 70, Issue:2 Topics: Acetylation; Adult; Drug Interactions; Female; Humans; Isoniazid; Kinetics; Male; Middle Aged; Theophylline	1987
[Critical view on intra-animal culture of microorganisms, a method for the detection of chemically-induced mutations]. Arzneimittel-Forschung, 1973, Volume: 23, Issue:6 Topics: Alkanesulfonates; Bacteria; Captan; Chloramphenicol; Cyclophosphamide; Dichlorvos; Escherichia coli; Isoniazid; Microbial Sensitivity Tests; Mutagens; Mutation; Neurospora crassa; Nitrosoguanidines; Piperazines; Salmonella typhimurium; Serratia marcescens; Streptozocin; Theophylline	1973
Special problems in respiratory diseases. Geriatrics, 1974, Volume: 29, Issue:6 Topics: Adrenal Cortex Hormones; Aged; Aging; Anti-Bacterial Agents; Anticoagulants; Asthma; Bronchodilator Agents; Drug Interactions; Epinephrine; Humans; Hypnotics and Sedatives; Infections; Isoniazid; Lung; Lung Diseases, Obstructive; Lung Neoplasms; Phenytoin; Pulmonary Embolism; Respiratory Tract Diseases; Theophylline; Tranquilizing Agents; Tuberculosis, Pulmonary	1974
Identification of drugs in the preimplantation blastocyst and in the plasma, uterine secretion and urine of the pregnant rabbit. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:1 Topics: Animals; Barbiturates; Caffeine; Carbon Isotopes; DDT; Embryo Implantation; Endometrium; Female; Isoniazid; Molecular Weight; Nicotine; Ovum; Pregnancy; Rabbits; Radioisotope Dilution Technique; Theophylline; Thiopental; Tritium; Uterus; Xanthines	1971
CYP1A2 activity as a risk factor for bladder cancer. Journal of Korean medical science, 1994, Volume: 9, Issue:6 Topics: Acetylation; Adult; Aged; Amines; Carcinoma, Transitional Cell; Case-Control Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Disease Susceptibility; Enzyme Induction; Female; Humans; Isoniazid; Korea; Logistic Models; Male; Methylation; Metoprolol; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Smoking; Theophylline; Uric Acid; Urinary Bladder Neoplasms	1994
Seizures associated with poisoning and drug overdose. The American journal of emergency medicine, 1993, Volume: 11, Issue:6 Topics: Adolescent; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Causality; Cause of Death; Child; Cocaine; Diphenhydramine; Drug Overdose; Humans; Isoniazid; Middle Aged; Poisoning; Population Surveillance; Retrospective Studies; Seizures; Theophylline	1993
Seizures induced by theophylline and isoniazid in mice. Veterinary and human toxicology, 1999, Volume: 41, Issue:3 Topics: Animals; Antitubercular Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Isoniazid; Mice; Pyridoxal Phosphate; Pyridoxine; Seizures; Theophylline	1999
Pyridoxine treatment for seizures induced by theophylline and isoniazid? Veterinary and human toxicology, 1999, Volume: 41, Issue:5 Topics: Animals; Drug Interactions; Isoniazid; Mice; Pyridoxine; Seizures; Theophylline	1999
[POTENTIATION BY THEOPHYLLINE AND CAFFEINE OF THE CONVULSANT EFFECTS AND TOXICITY OF ISONIAZID]. Annales pharmaceutiques francaises, 1964, Volume: 22 Topics: Caffeine; Convulsants; Isoniazid; Pharmacology; Rats; Research; Seizures; Theophylline; Toxicology	1964
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU. The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1 Topics: Animals; Area Under Curve; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activators; Half-Life; Infusions, Intravenous; Isoniazid; Metabolic Clearance Rate; Methylcholanthrene; Orphenadrine; Phosphodiesterase Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Theophylline; Uric Acid; Weight Gain	2008
Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Mar-01, Volume: 99 Topics: Aminosalicylic Acid; Antitubercular Agents; Caffeine; Crystallization; Crystallography, X-Ray; Drug Stability; Isoniazid; Models, Molecular; Niacinamide; Powder Diffraction; Pyrazinamide; Solubility; Theophylline; X-Ray Diffraction	2017