theophylline and interleukin-8

theophylline has been researched along with interleukin-8 in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's6 (25.00)18.2507
2000's6 (25.00)29.6817
2010's9 (37.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Driver, AG; Kukoly, CA; Metzger, WJ; Mustafa, SJ1
Bernstein, IL1
Bierman, CW1
Kobayashi, J; Kurita, C; Nagai, H; Nakao, T; Usami, E; Watanabe, S; Yamazaki, F; Yoshimura, T1
Inagaki, N; Kobayashi, J; Kurita, C; Nagai, H; Nagao, T; Nakao, T; Tanaka, H; Usami, E; Watanabe, S; Yamazaki, F; Yoshimura, T1
Church, MK; Holgate, ST; Shute, JK; Tenor, H1
Buratti, T; Dunzendorfer, S; Herold, M; Kähler, CM; Reinisch, N; Schratzberger, P; Tilg, H; Wiedermann, CJ1
Isumi, T; Koyama, S; Kubo, K; Masubuchi, T; Nagai, S; Sato, E; Takamizawa, A1
Dent, G; Djukanović, R; Hidi, R; Holgate, ST; Liu, E; Schudt, C; Timmermans, S1
Adcock, IM; Barnes, PJ; Cosio, BG; Ito, K; Jazrawi, E; Tsaprouni, L1
Ashitani, J; Iiboshi, H; Katoh, S; Matsumoto, N; Mukae, H; Nakazato, M; Sano, A1
Chen, YH; Ding, YL; Geng, B; Lu, M; Tang, CS; Yao, WZ1
Hagiwara, K; Kanazawa, M; Kikuchi, I; Kikuchi, S; Kobayashi, T; Nagata, M; Takaku, Y1
Hylkema, MN; Postma, DS; Timens, W; Versluis, M1
Akiyoshi, K; Izumi, T; Korematsu, S; Maeda, T; Miyahara, H; Nagakura, T; Okazaki, N; Suenobu, S; Yamamoto, K1
Feng, MX; Qu, JM; Zhang, J1
Deng, W; Gong, Y; Li, Q; Ren, L; Sun, X; Wan, H1
Druey, KM; Frith, K; Hsu, P; Kakakios, A; Stone, KD; Wong, M; Xie, Z1
Goud, M; Haghi, M; Traini, D; Young, PM; Zhu, B1
Ammit, AJ; Oliver, BG; Patel, BS; Rahman, MM; Rumzhum, NN; Verrills, NM1
Agusti, A; Barnes, PJ; Córdova, R; Cosío, BG; Gea, J; Iglesias, A; Palou, A; Pascual, S; Peces-Barba, G; Rodriguez-Roisin, R; Shafiek, H; Sibila, O; Yanez, A1
Bellon, H; Heigl, T; Hoet, P; Lammertyn, E; Mathyssen, C; Pilette, C; Sacreas, A; Vanaudenaerde, BM; Vandermeulen, E; Verleden, GM; Verleden, SE; Vos, R; Vriens, H1
Ammit, AJ; Baehring, G; Kugel, MJ; Patel, BS1
Chen, DD; Le Grange, JM; Zhang, JN; Zheng, XF; Zhou, LQ; Zhu, XL1

Reviews

1 review(s) available for theophylline and interleukin-8

ArticleYear
Postgraduate course presentation. Cromolyn sodium in the treatment of asthma: changing concepts.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4

    Topics: Administration, Intranasal; Airway Obstruction; Animals; Asthma; Bronchial Spasm; Chemotactic Factors; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Guinea Pigs; Haplorhini; Histamine Release; Humans; Interleukin-8; Long-Term Care; Mast Cells; Sulfur Dioxide; Theophylline

1981

Trials

4 trial(s) available for theophylline and interleukin-8

ArticleYear
Postgraduate course presentation. Cromolyn sodium in the treatment of asthma: changing concepts.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4

    Topics: Administration, Intranasal; Airway Obstruction; Animals; Asthma; Bronchial Spasm; Chemotactic Factors; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind Method; Guinea Pigs; Haplorhini; Histamine Release; Humans; Interleukin-8; Long-Term Care; Mast Cells; Sulfur Dioxide; Theophylline

1981
Long-term treatment with theophylline reduces neutrophils, interleukin-8 and tumor necrosis factor-alpha in the sputum of patients with chronic obstructive pulmonary disease.
    Pulmonary pharmacology & therapeutics, 2007, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Bronchodilator Agents; Cell Line; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Interleukin-8; Lipopolysaccharides; Male; Neutrophils; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Spirometry; Sputum; Theophylline; Time Factors; Tumor Necrosis Factor-alpha

2007
Effect of theophylline on endogenous hydrogen sulfide production in patients with COPD.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:1

    Topics: Aged; Blood Cell Count; Bronchodilator Agents; Female; Humans; Hydrogen Sulfide; Interleukin-8; Male; Middle Aged; Nitric Oxide; Phosphodiesterase Inhibitors; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests; Sputum; Theophylline

2008
Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial.
    Chest, 2016, Volume: 150, Issue:1

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aged; Anti-Inflammatory Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inflammation; Interleukin-6; Interleukin-8; Male; Middle Aged; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Symptom Flare Up; Theophylline; Treatment Outcome

2016

Other Studies

20 other study(ies) available for theophylline and interleukin-8

ArticleYear
Bronchial challenge with adenosine causes the release of serum neutrophil chemotactic factor in asthma.
    The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 1

    Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Male; Middle Aged; Neutrophils; Theophylline

1991
A comparison of late reactions to antigen and exercise.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 2

    Topics: Albuterol; Antigens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Chemotactic Factors; Cromolyn Sodium; Forced Expiratory Volume; Histamine Release; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Interleukin-8; Mast Cells; Methacholine Chloride; Methacholine Compounds; Respiratory Hypersensitivity; Skin Tests; Theophylline

1984
Effect of theophylline on the production of interleukin-1 beta, tumor necrosis factor-alpha, and interleukin-8 by human peripheral blood mononuclear cells.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cells, Cultured; Cytokines; Endotoxins; Humans; Interleukin-1; Interleukin-8; Lipopolysaccharides; Monocytes; Phytohemagglutinins; Theophylline; Tumor Necrosis Factor-alpha

1995
Inhibition of tumor necrosis factor-alpha and interleukin-1-beta production by beta-adrenoceptor agonists from lipopolysaccharide-stimulated human peripheral blood mononuclear cells.
    Pharmacology, 1997, Volume: 54, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cell Separation; Cells, Cultured; Clenbuterol; Cyclic AMP; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Fenoterol; Humans; Interleukin-1; Interleukin-8; Leukocytes, Mononuclear; Lipopolysaccharides; Procaterol; Propranolol; Terbutaline; Theophylline; Tumor Necrosis Factor-alpha; Vasodilator Agents

1997
Theophylline inhibits the release of eosinophil survival cytokines--is Raf-1 the protein kinase A target?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1998, Volume: 28 Suppl 3

    Topics: Bronchodilator Agents; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytokines; Enzyme-Linked Immunosorbent Assay; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoglobulin A, Secretory; Interleukin-8; Microspheres; Phospholipases A; Phospholipases A2; Theophylline; Time Factors

1998
Mediator-dependent effects of pentoxifylline on endothelium for transmigration of neutrophils.
    Immunopharmacology, 1999, Volume: 41, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adjuvants, Immunologic; Bucladesine; Cell Adhesion; Cell Movement; Endothelium, Vascular; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-1; Interleukin-8; Lipopolysaccharides; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha

1999
Procaterol inhibits IL-1beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity.
    The European respiratory journal, 1999, Volume: 14, Issue:4

    Topics: Adrenergic beta-Agonists; Bronchi; Cell Line; Chemokine CCL5; Chemotaxis, Leukocyte; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Eosinophils; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1; Interleukin-8; Intracellular Fluid; Phosphodiesterase Inhibitors; Procaterol; Radioimmunoassay; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Time Factors; Tumor Necrosis Factor-alpha

1999
Phosphodiesterase and cyclic adenosine monophosphate-dependent inhibition of T-lymphocyte chemotaxis.
    The European respiratory journal, 2000, Volume: 15, Issue:2

    Topics: Albuterol; Asthma; Bucladesine; Chemotaxis, Leukocyte; Colforsin; Cyclic AMP; Humans; Interleukin-8; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Activating Factor; Rolipram; T-Lymphocytes; Theophylline

2000
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.
    The Journal of experimental medicine, 2004, Sep-06, Volume: 200, Issue:5

    Topics: Aged; Blotting, Western; Bronchodilator Agents; Enzyme-Linked Immunosorbent Assay; Female; Glutathione; Histone Deacetylases; Humans; Hydroxamic Acids; Immunohistochemistry; Inflammation; Interleukin-8; Lipopolysaccharides; Macrophages; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Smoking; Steroids; Theophylline; Tumor Necrosis Factor-alpha; U937 Cells

2004
Theophylline attenuates the neutrophil-dependent augmentation of eosinophil trans-basement membrane migration.
    International archives of allergy and immunology, 2007, Volume: 143 Suppl 1

    Topics: Adult; Basement Membrane; Cells, Cultured; Chemotaxis, Leukocyte; Drug Evaluation, Preclinical; Eosinophils; Female; Humans; In Vitro Techniques; Interleukin-8; Leukotriene B4; Male; Neutrophils; Respiratory Burst; Superoxides; Theophylline

2007
Effects of IL-4 and IL-13 on adenosine receptor expression and responsiveness of the human mast cell line 1.
    International immunopharmacology, 2008, Volume: 8, Issue:6

    Topics: Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Bronchoconstriction; Cell Line, Tumor; Histamine Release; Humans; Interleukin-13; Interleukin-4; Interleukin-8; Mast Cells; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Theophylline; Vasodilator Agents

2008
The indication and effectiveness of low-dose erythromycin therapy in pediatric patients with bronchial asthma.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2010, Volume: 21, Issue:3

    Topics: Anti-Asthmatic Agents; Anti-Bacterial Agents; Asthma; Chemokine CCL11; Child; Child, Preschool; Dose-Response Relationship, Drug; Erythromycin; Female; Humans; Interleukin-8; Leukotriene Antagonists; Male; Pediatrics; Theophylline; Treatment Outcome; Vascular Endothelial Growth Factor A

2010
Low dose theophylline showed an inhibitory effect on the production of IL-6 and IL-8 in primary lung fibroblast from patients with COPD.
    Mediators of inflammation, 2012, Volume: 2012

    Topics: Aged; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Humans; Interleukin-6; Interleukin-8; Lung; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Real-Time Polymerase Chain Reaction; Theophylline

2012
Low-dose theophylline restores corticosteroid responsiveness in rats with smoke-induced airway inflammation.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:7

    Topics: Adrenal Cortex Hormones; Animals; Bronchoalveolar Lavage Fluid; Budesonide; Dose-Response Relationship, Drug; Histone Deacetylase 2; Inflammation; Interleukin-8; Lung; Male; Rats; Rats, Wistar; Smoke; Smoke Inhalation Injury; Smoking; Theophylline

2012
Idiopathic systemic capillary leak syndrome in children.
    Pediatrics, 2015, Volume: 135, Issue:3

    Topics: Capillary Leak Syndrome; Child; Child, Preschool; Edema; Humans; Infant; Interleukin-8; Male; Theophylline; Vasodilator Agents

2015
The formulation of a pressurized metered dose inhaler containing theophylline for inhalation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Aug-30, Volume: 76

    Topics: Administration, Inhalation; Aerosol Propellants; Aerosols; Anti-Inflammatory Agents; Bronchodilator Agents; Cell Line; Chemistry, Pharmaceutical; Drug Delivery Systems; Epithelial Cells; Equipment Design; Ethanol; Humans; Hydrocarbons, Fluorinated; Inflammation Mediators; Interleukin-8; Metered Dose Inhalers; Microscopy, Electron, Scanning; Particle Size; Pressure; Pulmonary Disease, Chronic Obstructive; Respiratory Mucosa; Solubility; Technology, Pharmaceutical; Theophylline; Tumor Necrosis Factor-alpha

2015
Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator.
    American journal of respiratory cell and molecular biology, 2016, Volume: 54, Issue:6

    Topics: A549 Cells; Anti-Inflammatory Agents; Cyclic AMP; Dual Specificity Phosphatase 1; Enzyme Activators; Formoterol Fumarate; Gene Knockdown Techniques; Humans; Interleukin-8; Lung; Myocytes, Smooth Muscle; Phosphodiesterase Inhibitors; Protein Phosphatase 2; RNA, Messenger; RNA, Small Interfering; Theophylline; Tumor Necrosis Factor-alpha; Up-Regulation

2016
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options.
    Transplant international : official journal of the European Society for Organ Transplantation, 2017, Volume: 30, Issue:4

    Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome

2017
Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect.
    Pulmonary pharmacology & therapeutics, 2017, Volume: 45

    Topics: Anti-Inflammatory Agents; Bronchi; Bronchodilator Agents; Cells, Cultured; Cyclic AMP; Cyclohexanecarboxylic Acids; Dual Specificity Phosphatase 1; Formoterol Fumarate; Humans; Inflammation; Interleukin-8; Myocytes, Smooth Muscle; Nitriles; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha

2017
Impacts of anti-inflammatory phosphodiesterase inhibitors on a murine model of chronic pulmonary inflammation.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:4

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Cyclopropanes; Disease Models, Animal; Histone Deacetylase 2; Interleukin-8; Lung; Male; Mice, Inbred C57BL; Nicotiana; Pentoxifylline; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Smoke; Smoking; Theophylline; Tumor Necrosis Factor-alpha

2021