theophylline and idazoxan

theophylline has been researched along with idazoxan in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Dieudonne, MN; Giudicelli, Y; Pecquery, R1
Dettmar, PW; Downing, OA; Roach, AG; Urquhart, CJ; Williams, RJ; Wilson, KA1
Majewski, H; Murphy, TV1
Doze, VA; Maze, M; Segal, IS; Vickery, RG; Walton, JK1
Puurunen, J1
Amobi, N; Smith, IC1
Curtis-Prior, PB; Tan, S1
Galligan, JJ; Ren, J1

Other Studies

12 other study(ies) available for theophylline and idazoxan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Characteristics of the alpha 2/beta-adrenoceptor-coupled adenylate cyclase system and their relationship with adrenergic responsiveness in hamster fat cells from different anatomical sites.
    European journal of biochemistry, 1992, Apr-15, Volume: 205, Issue:2

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Colforsin; Cricetinae; Dioxanes; Epididymis; Epinephrine; GTP-Binding Proteins; Idazoxan; Isoproterenol; Kinetics; Lipolysis; Macromolecular Substances; Male; Mesocricetus; Organ Specificity; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Skin; Theophylline

1992
Alpha 2-adrenoceptor antisecretory responses in the rat jejunum.
    Journal of autonomic pharmacology, 1990, Volume: 10, Issue:2

    Topics: Animals; Body Fluids; Brimonidine Tartrate; Dioxanes; Electric Stimulation; Electrolytes; Idazoxan; In Vitro Techniques; Jejunum; Male; Norepinephrine; Phenylephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetrodotoxin; Theophylline

1990
Modulation of noradrenaline release in slices of rat kidney cortex through alpha 1- and alpha 2-adrenoceptors.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Indomethacin; Kidney Cortex; Male; Methoxamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Theophylline

1989
Dexmedetomidine diminishes halothane anesthetic requirements in rats through a postsynaptic alpha 2 adrenergic receptor.
    Anesthesiology, 1988, Volume: 69, Issue:6

    Topics: Animals; Benzylamines; Brain; Dioxanes; Halothane; Idazoxan; Imidazoles; Male; Medetomidine; Naltrexone; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Stereoisomerism; Theophylline

1988
Role of putative neurotransmitters in the central gastric antisecretory effect of prostaglandin E2 in rats.
    British journal of pharmacology, 1985, Volume: 85, Issue:1

    Topics: 5,6-Dihydroxytryptamine; Adrenergic alpha-Antagonists; Animals; Dinoprostone; Dioxanes; Female; Fenclonine; Gastric Juice; Histamine Antagonists; Hydroxydopamines; Idazoxan; Injections, Intraventricular; Male; Naloxone; Neurotransmitter Agents; Oxidopamine; Phentolamine; Propranolol; Prostaglandins E; Rats; Rats, Inbred Strains; Sulpiride; Theophylline

1985
Effects of alpha,beta-methylene ATP on biphasic responses of rat vas deferens.
    European journal of pharmacology, 1987, Jan-06, Volume: 133, Issue:1

    Topics: Adenosine Triphosphate; Animals; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Purinergic; Theophylline; Vas Deferens

1987
Comparative effects of RX 781094, mianserin, yohimbine, rauwolscine and prazosin in reversing clonidine inhibition of MIX-stimulated lipolysis in hamster isolated white fat cells.
    Pharmacological research communications, 1984, Volume: 16, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Lipolysis; Male; Mianserin; Prazosin; Theophylline; Yohimbine

1984
Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum.
    Autonomic neuroscience : basic & clinical, 2005, Feb-07, Volume: 117, Issue:2

    Topics: Acetylcholine; Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Animals; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Estriol; Excitatory Postsynaptic Potentials; GABA Antagonists; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Iontophoresis; Male; Mecamylamine; Myenteric Plexus; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Nicotinic Antagonists; Peptides; Picrotoxin; Piperazines; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Serotonin 5-HT1 Receptor Antagonists; Theophylline; Time Factors

2005