theophylline has been researched along with ibuprofen in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (9.26) | 18.7374 |
| 1990's | 8 (14.81) | 18.2507 |
| 2000's | 17 (31.48) | 29.6817 |
| 2010's | 24 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Akamatsu, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bernaski, E; Bernstein, G; Braen, GR; Jehle, D | 1 |
| Walley, T | 1 |
| Biaggioni, I; Enayat, N; King, LS; Newman, JH; Robertson, D | 1 |
| Edlund, A; Sollevi, A; Wennmalm, A | 1 |
| Carlsson, I; Sollevi, A; Wennmalm, A | 1 |
| Bille-Hansen, V; Olsen, UB | 1 |
| Fujimoto, W; Metz, S; Robertson, RP | 1 |
| Häglund, BO; Sundelöf, LO; Upadrashta, SM | 1 |
| Bodmeier, R; Wang, J | 1 |
| Bopp, BA; Kukulka, MJ; Machinist, JM | 1 |
| Massart, B; Massart, DL; Remon, JP; Vervaet, C; Zhou, F | 1 |
| McGinity, JW; Wu, C | 1 |
| Degenhardt, V; Juergens, UR; Stöber, M; Vetter, H | 1 |
| Bujak-Gizycka, B; Kłys, M; Latacz, B; Skupień, E | 1 |
| English, JC; Swanson, JK | 1 |
| Eppel, GA; Evans, RG; Ventura, S | 1 |
| Goto, M; Hiramatsu, O; Kajiya, F; Mori, H; Ogasawara, Y; Shimokawa, H; Shinozaki, Y; Yada, T | 1 |
| Biswas, D; Ghosh, M; Mukherjee, A | 1 |
| Douroumis, D; Farrell, T; Levina, M; Nokhodchi, A; Palmer, D; Rajabi-Siahboomi, A | 1 |
| Danède, F; Delplace, C; Descamps, M; Klose, D; Kreye, F; Siepmann, F; Siepmann, J | 1 |
| Forbes, RT; Gray, J; Hulse, WL | 1 |
| Iwanaga, K; Kakemi, M; Kawai, M; Miyazaki, M | 1 |
| Aarons, L; Johnson, TN; Ogungbenro, K; Rostami-Hodjegan, A; Salem, F; Vajjah, P | 1 |
| Agarwal, K; Hicks, I; Kane, A; Kathiria, L; Kushner, J; Langdon, BA; Li, F; Ranade, G; Song, D | 1 |
| Al-Khattawi, A; Alyami, H; Ma, X; Mohammed, AR; Townsend, B | 1 |
| Chang, SY; Gong, X; Osei-Yeboah, F; Paul, S; Perumalla, SR; Shi, L; Sun, CC; Sun, WJ; Zhou, Q | 1 |
| Coboeken, K; Ince, I; Meyer, M; Schmidt, S; Schnizler, K; Somani, AA; Thelen, K; Trame, MN; Willmann, S; Zheng, S | 1 |
| Borek-Dohalska, L; Fojtikova, V; Martinkova, M; Mináriková, M; Sedláček, J; Šikut, M; Stiborová, M; Vyskočilová, E | 1 |
1 review(s) available for theophylline and ibuprofen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for theophylline and ibuprofen
| Article | Year |
|---|---|
New insights in the bronchodilatory and anti-inflammatory mechanisms of action of theophylline.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchodilator Agents; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Female; Humans; Ibuprofen; Leukotriene B4; Lipopolysaccharides; Male; Monocytes; Stimulation, Chemical; Theophylline | 1999 |
52 other study(ies) available for theophylline and ibuprofen
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Failure of gastric emptying and charcoal administration in fatal sustained-release theophylline overdose: pharmacobezoar formation.
Topics: Bezoars; Charcoal; Delayed-Action Preparations; Female; Humans; Ibuprofen; Middle Aged; Stomach; Theophylline | 1992 |
Drug interactions with OTCs.
Topics: Acetaminophen; Antacids; Aspirin; Drug Interactions; Histamine H1 Antagonists; Humans; Ibuprofen; Nonprescription Drugs; Sympathomimetics; Theophylline | 1991 |
Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Ibuprofen; Lung; Prostaglandin Endoperoxides; Pulmonary Circulation; Receptors, Purinergic; Sheep; Theophylline; Thromboxane A2; Thromboxane B2; Time Factors; Vasoconstriction | 1989 |
The role of adenosine and prostacyclin in coronary flow regulation in healthy man.
Topics: Adenosine; Adult; Coronary Circulation; Epoprostenol; Female; Humans; Ibuprofen; Male; Oxygen Consumption; Physical Exertion; Receptors, Purinergic; Theophylline | 1989 |
The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia.
Topics: Adenosine; Adult; Arteries; Constriction; Female; Forearm; Humans; Ibuprofen; Male; Muscle Contraction; Muscle Relaxation; Prostaglandins; Regional Blood Flow; Theophylline; Veins | 1987 |
Exaggerated hypotension by N-formylmethionylleucyl-phenylalanine in indomethacin pretreated rats. Role of toxic oxygen.
Topics: Animals; Ascorbic Acid; Blood Pressure; Dimethyl Sulfoxide; Endotoxins; Female; Glucagon; Hypotension; Ibuprofen; Indomethacin; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Rats; Rats, Inbred Strains; Theophylline | 1986 |
Modulation of insulin secretion by cyclic AMP and prostaglandin E: the effects of theophylline, sodium salicylate and tolbutamide.
Topics: Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Glucose; Ibuprofen; Insulin; Insulin Secretion; Islets of Langerhans; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium Salicylate; Theophylline; Tolbutamide | 1982 |
Diffusion and concentration profiles of drugs in gels.
Topics: Acetaminophen; Chlorpheniramine; Diffusion; Gels; Humans; Ibuprofen; Indomethacin; Pharmacokinetics; Temperature; Theophylline | 1993 |
Microencapsulation of drugs with aqueous colloidal polymer dispersions.
Topics: Capsules; Colloids; Delayed-Action Preparations; Ephedrine; Excipients; Guaifenesin; Ibuprofen; Microspheres; Solubility; Theophylline | 1993 |
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Anticoagulants; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hematocrit; Humans; Hydroxylation; Hydroxyurea; Ibuprofen; In Vitro Techniques; Isotope Labeling; Lipoxygenase Inhibitors; Male; Naproxen; Prednisolone; Protein Binding; Salicylates; Stereoisomerism; Terfenadine; Theophylline; Warfarin | 1995 |
Optimization of the processing of matrix pellets based on the combination of waxes and starch using experimental design.
Topics: Delayed-Action Preparations; Drug Compounding; Evaluation Studies as Topic; Humans; Ibuprofen; Starch; Theophylline; Waxes | 1998 |
Non-traditional plasticization of polymeric films.
Topics: Chlorpheniramine; Ibuprofen; Parabens; Plasticizers; Polymers; Tablets; Tensile Strength; Theophylline; Thermal Conductivity | 1999 |
[Two complex suicidal poisonings with drugs and their medicolegal aspects].
Topics: Adult; Atenolol; Chromatography, High Pressure Liquid; Diclofenac; Estazolam; Fatal Outcome; Female; Humans; Ibuprofen; Illicit Drugs; Ketoprofen; Male; Metronidazole; Naproxen; Poland; Suicide, Attempted; Theophylline; Tolperisone | 2001 |
Serum sickness-like reaction to Pamabrom.
Topics: Adult; Arm; Aspirin; Caffeine; Diagnosis, Differential; Drug Combinations; Ephedrine; Female; Humans; Leg; Phenacetin; Propanolamines; Serum Sickness; Theophylline | 2006 |
Regional vascular responses to ATP and ATP analogues in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cyclooxygenase Inhibitors; Ibuprofen; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Receptors, Purinergic P2; Regional Blood Flow; Renal Circulation; Theophylline | 2006 |
Important role of endogenous hydrogen peroxide in pacing-induced metabolic coronary vasodilation in dogs in vivo.
Topics: Animals; Antioxidants; Cardiac Pacing, Artificial; Catalase; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Dogs; Enzyme Inhibitors; Female; Hydrogen Peroxide; Ibuprofen; Male; Microcirculation; Microscopy, Fluorescence; Myocardium; Nitric Oxide; omega-N-Methylarginine; Oxygen Consumption; Potassium Channel Blockers; Tetraethylammonium; Theophylline; Vasodilation; Vasodilator Agents | 2007 |
High-altitude medicines: a short-term genotoxicity study.
Topics: Acetazolamide; Adult; Altitude Sickness; Analysis of Variance; Cell Survival; Cells, Cultured; Comet Assay; Dexamethasone; DNA; DNA Damage; Furosemide; Humans; Ibuprofen; Lymphocytes; Male; Mutagenicity Tests; Nifedipine; Theophylline | 2010 |
The influence of sodium carboxymethylcellulose on drug release from polyethylene oxide extended release matrices.
Topics: Carboxymethylcellulose Sodium; Delayed-Action Preparations; Ibuprofen; Polyethylene Glycols; Propranolol; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Theophylline; Water | 2011 |
Impact of the experimental conditions on drug release from parenteral depot systems: From negligible to significant.
Topics: Dexamethasone; Drug Implants; Ibuprofen; Infusions, Parenteral; Kinetics; Lactic Acid; Lidocaine; Lipids; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prilocaine; Propranolol; Theophylline; X-Ray Diffraction | 2012 |
A discriminatory intrinsic dissolution study using UV area imaging analysis to gain additional insights into the dissolution behaviour of active pharmaceutical ingredients.
Topics: Chemistry, Pharmaceutical; Drug Design; Ibuprofen; Indomethacin; Sodium Dodecyl Sulfate; Solubility; Spectrum Analysis, Raman; Technology, Pharmaceutical; Theophylline; Ultraviolet Rays; X-Ray Diffraction | 2012 |
Application of organogels as oral controlled release formulations of hydrophilic drugs.
Topics: Animals; Antipyrine; Delayed-Action Preparations; Drug Administration Routes; Gels; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Male; Ofloxacin; Rats; Rats, Wistar; Solubility; Soybean Oil; Stearic Acids; Suspensions; Theophylline | 2012 |
Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?
Topics: Adult; Area Under Curve; Biomedical Research; Caffeine; Child; Child, Preschool; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Itraconazole; Male; Midazolam; Models, Biological; Pharmacokinetics; Sample Size; Theophylline | 2014 |
A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes.
Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hardness; Ibuprofen; Lactose; Lubricants; Particle Size; Powders; Pressure; Solubility; Stearic Acids; Tablets; Theophylline | 2014 |
Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets.
Topics: Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Ibuprofen; Mannitol; Tablets; Theophylline | 2014 |
Dependence of tablet brittleness on tensile strength and porosity.
Topics: Amlodipine; Cellulose; Drugs, Chinese Herbal; Glyburide; Ibuprofen; Porosity; Powders; Salvia miltiorrhiza; Sildenafil Citrate; Silicon Dioxide; Stearic Acids; Tablets; Tensile Strength; Theophylline | 2015 |
Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.
Topics: Acetaminophen; Administration, Oral; Biopharmaceutics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Intestinal Absorption; Theophylline | 2016 |
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibuprofen; Imipramine; Oxazepam; Phenobarbital; Poisoning; Promethazine; Silicates; Theophylline | 2017 |