Compounds > theophylline

theophylline and hydralazine

theophylline has been researched along with hydralazine in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (47.06)	18.7374
1990's	1 (5.88)	18.2507
2000's	5 (29.41)	29.6817
2010's	3 (17.65)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Palkoski, Z; Pettinger, W; Renyi, E; Sheppard, H	1
Klaus, D; Klumpp, F; Rössler, R; Sadowski, P	2
Clark, BG; Vestal, RE	1
Chevillard, C; Saiag, B; Worcel, M	2
Chevillard, C; Mathieu, MN; Saiag, B; Worcel, M	1
Kuan, CJ; Tarng, JL; Tseng, CJ; Tung, CS	1
BRANCATI, B; SCAPELLATO, L	1

Reviews

1 review(s) available for theophylline and hydralazine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

16 other study(ies) available for theophylline and hydralazine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Angiotensin antagonism and antihypertensive activity of phosphodiesterase inhibiting agents. Life sciences. Pt. 1: Physiology and pharmacology, 1973, Jan-15, Volume: 12, Issue:2 Topics: Adult; Angiotensin II; Animals; Bethanechol Compounds; Blood Pressure; Bradykinin; Bretylium Compounds; Debrisoquin; Diazoxide; Dose-Response Relationship, Drug; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Imidazoles; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Phosphodiesterase Inhibitors; Rats; Theophylline; Vasodilator Agents	1973
[Plasma renin activity in venous renal blood and its stimulation by hydralazine and theophylline (author's transl)]. Klinische Wochenschrift, 1973, Sep-01, Volume: 51, Issue:17 Topics: Blood Pressure; Chemoreceptor Cells; Humans; Hydralazine; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Pressoreceptors; Renal Veins; Renin; Sodium; Theophylline	1973
[Renin activity in renal vein blood and its stimulation by various drugs]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79 Topics: Humans; Hydralazine; Hypertension; Hypertension, Renal; Renal Veins; Renin; Theophylline	1973
Adverse drug reactions in the elderly: case studies. Geriatrics, 1984, Volume: 39, Issue:12 Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonidine; Dienestrol; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydralazine; Lung Diseases; Male; Middle Aged; Nitrofurantoin; Pancreatitis; Papaverine; Peripheral Nervous System Diseases; Procainamide; Propranolol; Sulindac; Theophylline; Timolol	1984
Interactions between hydralazine, propildazine and purines on arterial smooth muscle. British journal of pharmacology, 1981, Volume: 73, Issue:4 Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Arteries; Hydralazine; Hydrazines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Propranolol; Purines; Pyridazines; Rats; Theophylline	1981
Hydralazine: effect on the outflow of noradrenaline and mechanical responses evoked by sympathetic nerve stimulation of the rat tail artery. British journal of pharmacology, 1980, Volume: 69, Issue:3 Topics: Animals; Arteries; Drug Interactions; Electric Stimulation; Hydralazine; In Vitro Techniques; Male; Norepinephrine; Rats; Sympathetic Nervous System; Tail; Theophylline; Time Factors; Vasoconstriction; Vasoconstrictor Agents	1980
Hydralazine: mode of action at the neuroarterial junction. Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6 Topics: Animals; Arteries; Dose-Response Relationship, Drug; Hydralazine; Hypertension; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Junction; Rats; Theophylline	1980
Effect of adenosine blockade on plasma renin activity and catecholamines. Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1993, Volume: 17, Issue:1 Topics: Adenosine; Animals; Blood Pressure; Caffeine; Consciousness; Epinephrine; Hydralazine; Kidney; Male; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renin; Renin-Angiotensin System; Secretory Rate; Sodium, Dietary; Theophylline; Xanthines	1993
[MEBUTAMATE ASSOCIATIONS IN ANTIHYPERTENSIVE THERAPY]. Minerva medica, 1963, Aug-25, Volume: 54 Topics: Antihypertensive Agents; Antipsychotic Agents; Carbamates; Ethylenediamines; Humans; Hydralazine; Hypertension; Papaverine; Reserpine; Theophylline	1963