theophylline and glyburide

theophylline has been researched along with glyburide in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (17.65)	18.7374
1990's	47 (46.08)	18.2507
2000's	23 (22.55)	29.6817
2010's	14 (13.73)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Basabe, JC; Chieri, RA; Farina, JM	2
Buitrago, A; Gylfe, E; Hellman, B; Idahl, LA; Johansson, M	1
Handler, JS; Keiser, HR; Zusman, RM	1
Blumenbach, L; Gerhards, E; Gutsche, H; Klein, W; Loge, O; Losert, W; Schillinger, E; Speck, U; Vetter, H; Wendt, H	1
Henry, JL; Li, H	1
Akai, K; Ashikawa, K; Kanatsuka, H; Komaru, T; Sato, K; Sekiguchi, N; Takishima, T; Wang, Y	1
Satoh, K; Taira, N; Yamada, H; Yoneyama, F	1
Balaban, RS; Fleming, J; Heineman, FW; Ince, C; Samaha, FF	1
Bang, L; Brønsgaard, AM; Nielsen-Kudsk, JE	1
Hellerström, C; Sandler, S; Welsh, M; Welsh, N	1
Draznin, B; Goodman, M; Leitner, JW; Steinberg, JP; Sussman, KE	1
Hellman, B; Idahl, LA; Lernmark, A; Sehlin, J; Täljedal, IB	2
Addah, SA; Crockford, PM; Powell, P	1
Loubatières, A; Loubatières-Mariani, MM	1
Howell, SL; Montague, W	1
Edwards, JC; Howell, SL; Montague, W	1
Ebert, R; Hillebrandt, O; Schwabe, U	1
Schatz, H	1
Efendić, S; Grill, V; Nylén, A; Ostenson, CG	1
Sehlin, J	1
Ashcroft, FM; Davies, AG; Paterson, DJ; Reid, JM	1
He, RR; Li, YL	3
Chiba, Y; Goto, M; Hiramatsu, O; Kajiya, F; Kimura, A; Lu, S; Ogasawara, Y; Tachibana, H; Tsujioka, K; Yada, T	1
Osmanović, SS; Pan, WJ; Shefner, SA	1
Adaniya, H; Hiraoka, M; Sawanobori, T; Yukisada, H	1
Mellemkjaer, S; Nielsen-Kudsk, JE	1
Bache, RJ; Duncker, DJ; Herrlinger, SK; Pavek, TJ; van Zon, NS	1
Abiko, Y; Hara, A	1
Chujo, M; Mohamed, MU; Mori, H; Nakazawa, H; Shinozaki, Y; Tanaka, E; Yamakawa, A	1
Downing, SE; Ilebekk, A; Kirkebøen, KA; Offstad, J	1
Akatsuka, Y; Egashira, K; Katsuda, Y; Narishige, T; Shimokawa, H; Takeshita, A; Ueno, H	1
Martin, PL; Potts, AA	1
Cohen, MV; Daly, JJ; Downey, JM; Thornton, JD; Tsuchida, A; Walsh, RS	1
Collins, P; Jiang, C	1
Carruthers, AM; Fozard, JR	1
Hurt, CM; Pelleg, A; Wang, L; Xu, J	1
Marshall, JM; Thomas, T; Turner, L	1
Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC	1
Krnjević, K; Zhu, PJ	2
Arkhammar, P; Berggren, PO; Bokvist, K; Hallberg, A; Nilsson, T; Rorsman, P; Sjöholm, A; Welsh, M; Welsh, N	1
Orito, K; Satoh, K; Taira, N	1
Angrisani, M; Cazzola, M; Loffreda, A; Matera, MG; Rossi, F	1
Lupichuk, SM; Tabrizchi, R	1
Bache, RJ; Duncker, DJ; Ishibashi, Y; van Zon, NS	1
Pfaffendorf, M; van Wezel, HB; van Zwieten, PA; Vroom, MB	1
Randall, MD	1
Brenner, HH; Burkart, V; Hartmann, B; Kolb, H	1
Bouchard, JF; Lamontagne, D	1
Armstead, WM	1
Askenasy, N; Navon, G	1
Krnjević, K; Tekkök, S; Zhao, YT	1
al-Nakkash, L; Cotton, CU	1
Dumont, L; Fontaine, E; Jasmin, G; Véronneau, M; Viau, S	1
Bari, F; Busija, DW; Louis, TM	1
Bache, RJ; Duncker, DJ; Ishibashi, Y; Zhang, J	1
André-Fouët, X; Gysembergh, A; Loufoua, J; Margonari, H; Minaire, Y; Ovize, A; Ovize, M	1
Bache, RJ; Duncker, DJ; Melchert, PJ; Traverse, JH	1
Hayashi, J; Iwai, T; Kawana, K; Nojiri, M; Takeo, S; Tanonaka, K; Yabe, K; Yamane, M; Yoshida, H	1
Imanishi, M; Satake, N; Shibata, S	1
Cinel, I; Gür, S	1
Arimura, K; Egashira, K; Shimokawa, H; Tada, H; Takeshita, A; Yamamoto, M	1
Becq, F; Bulteau, L; Dérand, R; Dormer, RL; Folli, C; Galietta, LJ; Joffre, M; Jougla, C; McNeilly, CM; Métayé, T; Mettey, Y; Morris, MR; Pereira, MM; Vierfond, JM; Zegarra-Moran, O	1
Feigl, EO; Gorman, MW; Richmond, KN; Tune, JD	1
Ralevic, V	1
Bardou, M; Dumas, J; Dumas, M; Goirand, F; Rochette, L	1
Koenig, HM; Pelligrino, DA; Santizo, RA; Xu, HL	1
Chen, S; He, RR; Li, DP	1
Dura, E; Jijakli, H; Malaisse, WJ; Oguzhan, B; Sener, A; Zhang, HX	1
Assen, YJ; Duncker, DJ; Fung, TY; Haitsma, DB; Merkus, D; Verdouw, PD	1
Dart, C; Hayabuchi, Y; Sampson, LJ; Standen, NB	1
Cavalcante, IJ; Lima, MA; Maia, JL; Melo, CM; Rao, VS; Santos, FA; Silveira, ER; Vieira, GA	1
Fujita, H; Imamaki, M; Ishida, A; Kimura, F; Miyazaki, M; Nakaya, H; Ogura, T; Sato, T; Tamagawa, M; Uemura, H	1
Bache, RJ; Chen, Y; Hou, M; Li, Y; Traverse, JH	1
Andersson, M; Aronsson, P; Ericsson, T; Giglio, D	1
Boydens, C; Maenhaut, N; Van de Voorde, J	1
Ledent, C; Mustafa, SJ; Teng, B; Tilley, S; Zhou, X	1
Chang, SY; Gong, X; Osei-Yeboah, F; Paul, S; Perumalla, SR; Shi, L; Sun, CC; Sun, WJ; Zhou, Q	1

Reviews

3 review(s) available for theophylline and glyburide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The role of calcium in insulin secretion. Nutrition reviews, 1973, Volume: 31, Issue:4 Topics: Animals; Butyrates; Calcium; Calcium Isotopes; Cyclic AMP; Glucose; Glyburide; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Obesity; Potassium; Rats; Theophylline	1973
ATP-sensitive K+ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise. Circulation research, 1998, Feb-23, Volume: 82, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Coronary Vessels; Dogs; Enzyme Inhibitors; Glyburide; Hemodynamics; Hyperemia; Nitric Oxide; Nitroarginine; Physical Exertion; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilation	1998

Other Studies

99 other study(ies) available for theophylline and glyburide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently. Chemical biology & drug design, 2016, Volume: 88, Issue:6 Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Studies on the dynamics and mechanism of glibenclamide-induced insulin secretion. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Glyburide; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Puromycin; Rats; Theophylline	1976
In vitro insulin secretion from the penguin (Pygoscelis papua) pancreas. General and comparative endocrinology, 1975, Volume: 27, Issue:1 Topics: Animals; Arginine; Birds; Cyclic AMP; Glucose; Glyburide; Insulin; Insulin Secretion; Isoproterenol; Keto Acids; Ouabain; Pancreas; Phentolamine; Propranolol; Theophylline	1975
Function of microdissected pancreatic islets cultured in a chemically defined medium. I. Insulin content and release. Diabetologia, 1975, Volume: 11, Issue:6 Topics: Animals; Arginine; Bucladesine; Culture Media; Culture Techniques; Dissection; Drug Synergism; Female; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Mice; Mice, Obese; Stimulation, Chemical; Theophylline	1975
Inhibition of vasopressin-stimulated prostaglandin E biosynthesis by chlorpropamide in the toad urinary bladder. Mechanism of enhancement of vasopressin-stimulated water flow. The Journal of clinical investigation, 1977, Volume: 60, Issue:6 Topics: Animals; Anura; Arginine Vasopressin; Chlorpropamide; Chromatography, Thin Layer; Cyclic AMP; Glyburide; Lipid Metabolism; Permeability; Prostaglandins E; Stimulation, Chemical; Structure-Activity Relationship; Theophylline; Tolbutamide; Urinary Bladder; Vasopressins; Water	1977
Gliflumide, a new oral antidiabetic of high potency and efficacy. International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2 Topics: Administration, Oral; Animals; Blood Glucose; Cricetinae; Dogs; Fatty Acids, Nonesterified; Glucose; Glyburide; Humans; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Kinetics; Pyrimidines; Rats; Stereoisomerism; Sulfonamides; Theophylline; Tolbutamide	1975
Adenosine-induced hyperpolarization is depressed by glibenclamide in rat CA1 neurones. Neuroreport, 1992, Volume: 3, Issue:12 Topics: 2-Chloroadenosine; Adenosine; Animals; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Tetrodotoxin; Theophylline	1992
Microvascular sites and mechanisms responsible for reactive hyperemia in the coronary circulation of the beating canine heart. Circulation research, 1992, Volume: 71, Issue:4 Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hyperemia; Male; Microcirculation; Microscopy; Potassium Channels; Theophylline; Vasodilation	1992
Vasodepressor mechanisms of 2-(1-octynyl)-adenosine (YT-146), a selective adenosine A2 receptor agonist, involve the opening of glibenclamide-sensitive K+ channels. European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2 Topics: Adenosine; Alkynes; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Injections, Intravenous; Male; Norepinephrine; Potassium Channels; Receptors, Purinergic; Theophylline	1992
ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo. The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 1 Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Energy Metabolism; Glyburide; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mitochondria, Heart; Oxidation-Reduction; Perfusion; Phosphates; Phosphorylation; Potassium Channels; Rabbits; Spectrum Analysis; Theophylline; Vascular Resistance; Vasomotor System	1992
Glibenclamide blocks the relaxant action of pinacidil and cromakalim in airway smooth muscle. European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3 Topics: Animals; Benzopyrans; Cromakalim; Female; Glyburide; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Pinacidil; Pyrroles; Terbutaline; Theophylline; Trachea; Verapamil	1990
Regulation of RNA metabolism in relation to insulin production and oxidative metabolism in mouse pancreatic islets in vitro. Biochimica et biophysica acta, 1986, Jun-16, Volume: 887, Issue:1 Topics: Animals; Cells, Cultured; Glucose; Glyburide; Insulin; Islets of Langerhans; Kinetics; Leucine; Male; Mice; Mice, Inbred Strains; Oxygen Consumption; RNA; Theophylline; Transcription, Genetic	1986
Control of secretion vesicle margination and lysis by glucose, IBMX, and glyburide. The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calmodulin; Cell Membrane; Cytoplasmic Granules; Exocytosis; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Somatostatin; Somatostatin; Stimulation, Chemical; Theophylline; Trifluoperazine	1985
Iodoacetamide-induced sensitization of the pancreatic beta-cells to glucose stimulation. The Biochemical journal, 1973, Volume: 132, Issue:4 Topics: Amides; Animals; Calcium; Carbon Isotopes; Dithiothreitol; Epinephrine; Female; Fructosephosphates; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Iodine Isotopes; Iodoacetates; Islets of Langerhans; Leucine; Male; Mice; Obesity; Radioimmunoassay; Theophylline; Tritium	1973
Effect of sulfonylureas on the secretion of pancreatic immunoreactive glucagon and enteric glucagon-like immunoreactivity. Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:12 Topics: Animals; Antibody Formation; Antigens; Arginine; Glucagon; Glucose; Glyburide; In Vitro Techniques; Insulin Antibodies; Pancreas; Radioimmunoassay; Rats; Sulfonylurea Compounds; Theophylline; Tolbutamide	1973
In vitro secretion of insulin after glucose, sulphonylureas, adrenergic and cholinergic substances studied by isolated perfused rat pancreas. Endocrinologia experimentalis, 1974, Volume: 8, Issue:2 Topics: Acetylcholine; Animals; Atropine; Diazoxide; Epinephrine; Glucagon; Glucose; Glyburide; Heptoses; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Ketoses; Norepinephrine; Pancreas; Parasympathomimetics; Perfusion; Phenoxybenzamine; Practolol; Propranolol; Sulfonylurea Compounds; Theophylline; Tolbutamide	1974
The pancreatic beta-cell recognition of insulin secretagogues. Comparisons of glucose with glyceraldehyde isomers and dihydroxyacetone. Archives of biochemistry and biophysics, 1974, Volume: 162, Issue:2 Topics: Acetone; Animals; Arginine; Calcium; Carbon Radioisotopes; Dinitrophenols; Epinephrine; Female; Glucosamine; Glucose; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Iodoacetates; Islets of Langerhans; Isomerism; Leucine; Male; Obesity; Phlorhizin; Theophylline; Time Factors	1974
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity. The Biochemical journal, 1973, Volume: 134, Issue:1 Topics: Animals; Arginine; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucagon; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phosphorus Isotopes; Phosphotransferases; Protein Kinases; Rats; Theophylline; Time Factors; Tolbutamide; Xanthines; Xylitol	1973
Regulation of adenylate cyclase and cyclic-AMP dependent protein kinase activities in A2-cell rich guinea-pig islets of Langerhans. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: 6, Issue:1 Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Arginine; Bucladesine; Cyclic AMP; Diazoxide; Epinephrine; Fluorides; Glucagon; Glyburide; Guinea Pigs; Islets of Langerhans; Leucine; Male; Microbial Collagenase; Phosphorus Radioisotopes; Protein Kinases; Radioimmunoassay; Streptozocin; Theophylline	1974
Role of calcium and cyclic adenosine 3',5'-monophosphate in the antilipolytic effect of tolbutamide and glibenclamide. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 286, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; Carboxylic Acids; Cyclic AMP; Epinephrine; Glucagon; Glyburide; Isoproterenol; Lipid Metabolism; Male; Norepinephrine; Rats; Theophylline; Tolbutamide	1974
[The pancreatic beta-cell in the field of current diabetology]. Acta medica Austriaca, 1974, Volume: 3, Issue:1 Topics: Blood Glucose; Cyclic AMP; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Glyburide; Growth Hormone; Humans; Hyperinsulinism; Insulin; Insulin Secretion; Liver Cirrhosis; Pancreas; Secretory Rate; Theophylline	1974
Modulation by IBMX, fasting and experimental diabetes of glibenclamide-induced islet hormone release from the perfused rat pancreas. Diabete & metabolisme, 1983, Volume: 9, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fasting; Glucagon; Glyburide; Insulin; Insulin Secretion; Male; Pancreas; Pancreatic Hormones; Rats; Rats, Inbred Strains; Somatostatin; Theophylline	1983
Are Cl- mechanisms in mouse pancreatic islets involved in insulin release? Upsala journal of medical sciences, 1981, Volume: 86, Issue:2 Topics: Animals; Cell Membrane Permeability; Chlorides; Furosemide; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Mice; Theophylline	1981
Effect of L-NMMA, cromakalim, and glibenclamide on cerebral blood flow in hypercapnia and hypoxia. The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2 Topics: Animals; Arginine; Arteries; Benzopyrans; Cerebrovascular Circulation; Cromakalim; Glyburide; Hypercapnia; Hypoxia; Nitric Oxide Synthase; omega-N-Methylarginine; Pyrroles; Rats; Theophylline; Vasodilator Agents	1995
Effects of N6-cyclopentyladenosine on afterdepolarizations and triggered activity induced by isoproterenol in guinea pig papillary muscle. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:2 Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Papillary Muscles; Theophylline	1995
Direct in vivo observation of subendocardial arteriolar response during reactive hyperemia. Circulation research, 1995, Volume: 77, Issue:3 Topics: Adenosine; Animals; Arginine; Arterioles; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Theophylline; Vasodilation	1995
Characterization of the adenosine A1 receptor-activated potassium current in rat locus ceruleus neurons. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1 Topics: 4-Aminopyridine; Adenosine; Animals; Barium; Dose-Response Relationship, Drug; Glyburide; Locus Coeruleus; Male; Membrane Potentials; Neurons; Potassium Channels; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Theophylline	1995
Role for ATP-sensitive K+ channel in the development of A-V block during hypoxia. Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:1 Topics: Action Potentials; Adenosine Triphosphate; Animals; Atrioventricular Node; Deoxyglucose; Female; Glucose; Glyburide; Heart; Heart Block; Hypoxia; In Vitro Techniques; Kinetics; Male; Perfusion; Potassium Channels; Rabbits; Theophylline; Time Factors	1995
Endogenous adenosine and ATP-sensitive potassium channel modulate anoxia-induced electrophysiological changes of pacemaker cells in sinoatrial node of guinea pigs. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:1 Topics: Action Potentials; Adenosine Deaminase; Adenosine Triphosphate; Animals; Cell Hypoxia; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Microelectrodes; Potassium Channels; Sinoatrial Node; Theophylline	1995
Glibenclamide inhibits hypoxic relaxation of isolated porcine coronary arteries under conditions of impaired glycolysis. European journal of pharmacology, 1994, Aug-03, Volume: 270, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Benzopyrans; Coronary Vessels; Cromakalim; Deoxyglucose; Endothelium, Vascular; Glyburide; Glycolysis; Hypoxia; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Swine; Theophylline; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents	1994
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade. The Journal of clinical investigation, 1995, Volume: 95, Issue:1 Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyperemia; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Nitroprusside; Oxygen Consumption; Physical Conditioning, Animal; Pinacidil; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Systole; Theophylline; Vasodilation	1995
Protective effect of hypoxia on mechanical and metabolic changes induced by hydrogen peroxide in rat hearts. The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 2 Topics: Animals; Glyburide; Heart; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Male; Myocardium; Purinergic Antagonists; Rats; Theophylline; Xanthines	1995
Modulation of adrenergic coronary vasoconstriction via ATP-sensitive potassium channel. The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2 Topics: Adenosine; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Coronary Circulation; Dogs; Electric Stimulation; Glyburide; Guanidines; Neuropeptide Y; Nitric Oxide; Norepinephrine; Peptide Fragments; Pinacidil; Potassium Channels; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction	1995
ATP gated potassium channels in acute myocardial hibernation and reperfusion. Cardiovascular research, 1994, Volume: 28, Issue:6 Topics: Adenosine Triphosphate; Animals; Glyburide; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Perfusion; Picolines; Potassium Channels; Pressure; Pyrans; Rabbits; Swine; Theophylline; Vasodilator Agents	1994
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog. Cardiovascular research, 1994, Volume: 28, Issue:6 Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Glyburide; Guanidines; Ion Channel Gating; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Vasodilator Agents; Xanthines	1994
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Theophylline; Vasodilator Agents; Xanthines	1994
Ketamine-xylazine anaesthesia permits a KATP channel antagonist to attenuate preconditioning in rabbit myocardium. Cardiovascular research, 1994, Volume: 28, Issue:9 Topics: Animals; Glyburide; Guanidines; Ketamine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline; Vasodilator Agents; Xylazine	1994
Electrophysiological effects of N6-cyclopentyl-adenosine and [-]-N6-[phenylisopropyl]-adenosine on pacemaker cells in sinoatrial node of guinea pigs. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:5 Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Female; Glyburide; Guinea Pigs; Male; Microelectrodes; Phenylisopropyladenosine; Sinoatrial Node; Theophylline	1993
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. British journal of pharmacology, 1994, Volume: 111, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline	1994
The cardiovascular effects of selective adenosine A1 and A2 receptor agonists in the pithed rat: no role for glibenclamide-sensitive potassium channels. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:2 Topics: Adenosine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cardiovascular System; Cyclopentanes; Glyburide; Heart Rate; Male; Parasympatholytics; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Sensitivity and Specificity; Theophylline; Time Factors	1993
Endogenous adenosine does not activate ATP-sensitive potassium channels in the hypoxic guinea pig ventricle in vivo. Circulation, 1994, Volume: 89, Issue:3 Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Cardiac Pacing, Artificial; Cell Hypoxia; Glyburide; Guanidines; Guinea Pigs; Heart Conduction System; Myocardium; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Stereoisomerism; Theophylline	1994
A link between adenosine, ATP-sensitive K+ channels, potassium and muscle vasodilatation in the rat in systemic hypoxia. The Journal of physiology, 1993, Volume: 472 Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Hypoxia; Muscles; Potassium; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Vasodilation	1993
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens. European journal of pharmacology, 1993, Jun-11, Volume: 237, Issue:1 Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents	1993
Adenosine release is a major cause of failure of synaptic transmission during hypoglycaemia in rat hippocampal slices. Neuroscience letters, 1993, Jun-11, Volume: 155, Issue:2 Topics: Action Potentials; Adenosine; Animals; Caffeine; Cell Hypoxia; Energy Metabolism; Evoked Potentials; Glucose; Glyburide; Hippocampus; Hypoglycemia; Neural Inhibition; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline; Tolbutamide	1993
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity. The Journal of clinical investigation, 1993, Volume: 92, Issue:4 Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Cytoplasm; Diazoxide; DNA, Neoplasm; Eflornithine; Glucose; Glyburide; Inositol Phosphates; Insulin; Insulin Secretion; Insulinoma; Kinetics; Pancreatic Neoplasms; Polyamines; Potassium; Putrescine; Rats; RNA, Messenger; Spermidine; Spermine; Tetradecanoylphorbol Acetate; Theophylline; Tolbutamide; Tumor Cells, Cultured	1993
Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs. European journal of pharmacology, 1993, Feb-09, Volume: 231, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; In Vitro Techniques; Injections, Intra-Arterial; Male; Muscle Contraction; Myocardial Contraction; Papillary Muscles; Potassium Channels; Theophylline; Vasodilation	1993
Teicoplanin with other drugs: possible pharmacological interactions. Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:1 Topics: Animals; Drug Interactions; Female; Glyburide; Hypoglycemic Agents; Male; Phenformin; Rabbits; Rats; Teicoplanin; Theophylline; Warfarin	1993
Vasodilatation produced by adenosine in isolated rat perfused mesenteric artery: a role for endothelium. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:4 Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Glyburide; Male; Mesenteric Arteries; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Suramin; Theobromine; Theophylline; Vasodilation; Vasodilator Agents	1995
Role of K+ ATP channels and adenosine in the regulation of coronary blood flow during exercise with normal and restricted coronary blood flow. The Journal of clinical investigation, 1996, Feb-15, Volume: 97, Issue:4 Topics: Adenosine; Animals; Coronary Circulation; Dogs; Glyburide; Guanidines; Hemodynamics; Myocardial Contraction; Physical Exertion; Pinacidil; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents	1996
Effect of phosphodiesterase inhibitors on human arteries in vitro. British journal of anaesthesia, 1996, Volume: 76, Issue:1 Topics: Adolescent; Adult; Amrinone; Analgesics; Anilides; Arginine; Arteries; Dipyridamole; Enoximone; Female; Glyburide; Humans; In Vitro Techniques; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Theophylline; Vasoconstriction; Vasodilation	1996
The involvement of ATP-sensitive potassium channels and adenosine in the regulation of coronary flow in the isolated perfused rat heart. British journal of pharmacology, 1995, Volume: 116, Issue:7 Topics: Adenosine; Adenosine Triphosphate; Animals; Benzopyrans; Coronary Circulation; Cromakalim; Glyburide; Heart; In Vitro Techniques; Male; Perfusion; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Theophylline; Vasoconstrictor Agents; Vasodilator Agents	1995
Metabolic activation of islet cells improves resistance against oxygen radicals or streptozocin, but not nitric oxide. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:11 Topics: Animals; Drug Resistance; Free Radicals; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Islets of Langerhans; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Theophylline	1996
Mechanisms of protection afforded by preconditioning to endothelial function against ischemic injury. The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2 Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Endothelium, Vascular; Glyburide; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Vascular Resistance	1996
Role of nitric oxide, cyclic nucleotides, and the activation of ATP-sensitive K+ channels in the contribution of adenosine to hypoxia-induced pial artery dilation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:1 Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Arteries; Blood Pressure; Cyclic AMP; Cyclic GMP; Enkephalin, Leucine; Enkephalin, Methionine; Female; Glyburide; Hypoxia; Male; Nitric Oxide; Nucleotides, Cyclic; Pia Mater; Potassium Channels; Swine; Theophylline; Vasodilation; Vasodilator Agents	1997
Adenosine release mediates cyanide-induced suppression of CA1 neuronal activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Apr-01, Volume: 17, Issue:7 Topics: Adenosine; Animals; Dipyridamole; Evoked Potentials; Excitatory Postsynaptic Potentials; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Cyanide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Theophylline; Xanthines	1997
Intermittent ischemia: energy metabolism, cellular volume regulation, adenosine and insights into preconditioning. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:6 Topics: Adenosine; Animals; Cell Size; Creatine; Energy Metabolism; Glyburide; Glycogen; Glycolysis; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Perfusion; Phosphorus; Phosphorylation; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline	1997
2-Deoxy-D-glucose-induced changes in membrane potential, input resistance, and excitatory postsynaptic potentials of CA1 hippocampal neurons. Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:5 Topics: Animals; Antimetabolites; Deoxyglucose; Electric Impedance; Glyburide; Hippocampus; Hypoglycemic Agents; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline	1997
Bovine pancreatic duct cells express cAMP- and Ca(2+)-activated apical membrane Cl- conductances. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anions; Calcium; Cattle; Cell Line; Cells, Cultured; Chelating Agents; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Egtazic Acid; Epithelial Cells; Epithelium; Glyburide; Ionomycin; Kinetics; Membrane Potentials; ortho-Aminobenzoates; Pancreatic Ducts; Theophylline	1997
Myocardial reactive hyperemia in experimental chronic heart failure: evidence for the role of K+ adenosine triphosphate-dependent channels and cyclooxygenase activity. Journal of cardiac failure, 1997, Volume: 3, Issue:3 Topics: Animals; Cardiac Output, Low; Chronic Disease; Coronary Circulation; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Glyburide; Hyperemia; Indomethacin; NG-Nitroarginine Methyl Ester; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Theophylline	1997
Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets. Stroke, 1998, Volume: 29, Issue:1 Topics: Adenosine; Adenosine Triphosphate; Administration, Topical; Analysis of Variance; Animals; Arterioles; Brain; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Female; Glyburide; Hypercapnia; Hypoglycemic Agents; Hypoxia; Injections, Intravenous; Intracranial Hypertension; Male; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Reperfusion; Swine; Theophylline; Vasodilation; Vasodilator Agents	1998
Stretch-induced protection shares a common mechanism with ischemic preconditioning in rabbit heart. The American journal of physiology, 1998, Volume: 274, Issue:3 Topics: Animals; Coronary Circulation; Elasticity; Glyburide; Heart; Hematocrit; Hemodynamics; Ischemic Preconditioning, Myocardial; Mechanoreceptors; Myocardial Infarction; Polymyxin B; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Theophylline	1998
Role of K(+)(ATP) channels and adenosine in regulation of coronary blood flow in the hypertrophied left ventricle. The American journal of physiology, 1999, Volume: 277, Issue:2 Pt 2 Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Drug Combinations; Glyburide; Hypertrophy, Left Ventricular; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline	1999
Involvement of adenosine receptor, potassium channel and protein kinase C in hypoxic preconditioning of isolated cardiomyocytes of adult rat. Japanese journal of pharmacology, 1999, Volume: 80, Issue:1 Topics: Animals; Cell Hypoxia; Cytoprotection; Drug Interactions; Glyburide; Hypoglycemic Agents; Ischemic Preconditioning, Myocardial; Male; Myocardium; Oxygen; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline	1999
Increased nitroglycerin-induced relaxation by genistein in rat aortic rings. European journal of pharmacology, 1999, Jul-21, Volume: 377, Issue:2-3 Topics: Animals; Aorta; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Genistein; Glyburide; Isoflavones; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Peptides; Phenylephrine; Phosphoric Diester Hydrolases; Protein-Tyrosine Kinases; Pyridazines; Rats; Rats, Wistar; Theophylline; Vasoconstrictor Agents; Vasodilator Agents	1999
Direct inotropic effects of propofol and adenosine on rat atrial muscle: possible mechanisms. Pharmacological research, 2000, Volume: 42, Issue:2 Topics: Adenosine; Anesthetics, Intravenous; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Glyburide; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Potassium Channel Blockers; Potassium Channels; Propofol; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Theophylline; Vasodilator Agents	2000
Coronary vascular K+ATP channels contribute to the maintenance of myocardial perfusion in dogs with pacing-induced heart failure. Japanese circulation journal, 2000, Volume: 64, Issue:9 Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Heart Failure; Myocardial Ischemia; Nitroarginine; Pacemaker, Artificial; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline	2000
Properties of CFTR activated by the xanthine derivative X-33 in human airway Calu-3 cells. American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Caffeine; Calcium Channel Blockers; Chlorides; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Iodides; Iodine Radioisotopes; Membrane Potentials; Membrane Proteins; ortho-Aminobenzoates; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Respiratory Mucosa; Theophylline; Xanthines	2000
K(ATP)(+) channels, nitric oxide, and adenosine are not required for local metabolic coronary vasodilation. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Male; Myocardium; Nitric Oxide; Nitroarginine; Oxygen; Oxygen Consumption; Physical Exertion; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rest; Theophylline; Vasodilation	2001
Mechanism of prolonged vasorelaxation to ATP in the rat isolated mesenteric arterial bed. British journal of pharmacology, 2001, Volume: 132, Issue:3 Topics: Adenosine Triphosphate; Animals; Capsaicin; Cardiotonic Agents; Cardiovascular Agents; Charybdotoxin; Drug Interactions; Electric Stimulation; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Mesenteric Arteries; Neurons, Afferent; Ouabain; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Tetraethylammonium; Theophylline; Vasodilation	2001
Effects of phosphodiesterase inhibitors on hypoxic pulmonary vasoconstriction. Influence of K(+) channels and nitric oxide. European journal of pharmacology, 2001, Apr-06, Volume: 417, Issue:1-2 Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Potassium Channels; Purinones; Rats; Rats, Wistar; Rolipram; Theophylline; Vasoconstriction	2001
Chronic estrogen depletion alters adenosine diphosphate-induced pial arteriolar dilation in female rats. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antifungal Agents; Arterioles; Calcium; Cardiovascular Agents; Endothelium, Vascular; Estrogens; Female; Glyburide; Hypoglycemic Agents; Indomethacin; Miconazole; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Ovariectomy; Peptides; Pia Mater; Potassium Channels; Rats; Rats, Sprague-Dawley; Theophylline; Vasodilation	2001
Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats. Sheng li xue bao : [Acta physiologica Sinica], 2000, Volume: 52, Issue:4 Topics: Adenosine; Animals; Blood Pressure; Glyburide; Heart Rate; Kidney; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Theophylline; Xanthines	2000
Insulinotropic action of amino acids at their physiological concentrations: I. Experiments in incubated islets. International journal of molecular medicine, 2002, Volume: 9, Issue:5 Topics: Amino Acids; Animals; Calcium; Cells, Cultured; Colforsin; Cytochalasin B; Female; Glucose; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Wistar; Theophylline	2002
Coronary blood flow regulation in exercising swine involves parallel rather than redundant vasodilator pathways. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1 Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Circulation; Enzyme Inhibitors; Female; Glyburide; Hemodynamics; Hypoglycemic Agents; In Vitro Techniques; KATP Channels; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxygen Consumption; Physical Exertion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rest; Swine; Theophylline; Vasodilation	2003
Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels. Circulation research, 2004, Nov-12, Volume: 95, Issue:10 Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Aorta; ATP-Binding Cassette Transporters; Calcitonin Gene-Related Peptide; Caveolae; Caveolin 1; Caveolins; Cell Compartmentation; Cell Fractionation; Cholesterol; Cyclic AMP-Dependent Protein Kinases; Glyburide; Guanosine Diphosphate; Ion Transport; Isoenzymes; KATP Channels; Male; Membrane Lipids; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Peptide Fragments; Pinacidil; Potassium; Potassium Channels, Inwardly Rectifying; Propranolol; Rats; Rats, Wistar; Sphingolipids; Theophylline; Thionucleotides	2004
12-Acetoxyhawtriwaic acid lactone, a diterpene from Egletes viscosa, attenuates capsaicin-induced ear edema and hindpaw nociception in mice: possible mechanisms. Planta medica, 2006, Volume: 72, Issue:7 Topics: Analgesics; Animals; Asteraceae; Capsaicin; Diterpenes; Diterpenes, Clerodane; Ear; Edema; Flowers; Glyburide; Hindlimb; Lactones; Male; Mice; Naloxone; Nociceptors; Substance P; Theophylline; TRPV Cation Channels	2006
A key role for the subunit SUR2B in the preferential activation of vascular KATP channels by isoflurane. British journal of pharmacology, 2006, Volume: 149, Issue:5 Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; ATP-Binding Cassette Transporters; Cell Line; Cells, Cultured; Coronary Circulation; Dose-Response Relationship, Drug; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glyburide; Humans; In Vitro Techniques; Isoflurane; Membrane Potentials; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Theophylline; Transfection; Vasodilation	2006
Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure. Circulation research, 2007, Jun-08, Volume: 100, Issue:11 Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Cardiac Pacing, Artificial; Coronary Circulation; Disease Models, Animal; Dogs; Exercise Test; Glyburide; Heart; Heart Failure; Oxygen Consumption; Physical Exertion; Pinacidil; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rest; Theophylline; Vasodilator Agents	2007
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder. Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:1 Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Antagonism; Electric Stimulation; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Theophylline; Uracil Nucleotides; Urinary Bladder; Xanthines	2010
Hypoxia enhances the relaxing influence of perivascular adipose tissue in isolated mice aorta. European journal of pharmacology, 2010, Sep-01, Volume: 641, Issue:2-3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adipose Tissue; Animals; Aorta, Thoracic; Arteries; Cell Hypoxia; Dinoprost; Glyburide; Guanylate Cyclase; Male; Mice; Norepinephrine; Potassium; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfides; Tetraethylammonium; Theophylline; Vasodilation	2010
Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts. American journal of physiology. Heart and circulatory physiology, 2014, Oct-01, Volume: 307, Issue:7 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Coronary Circulation; Free Radical Scavengers; Glyburide; Heart; Hydrogen Peroxide; Hyperemia; In Vitro Techniques; KATP Channels; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Potassium Channel Blockers; Pyrimidines; Receptors, Purinergic P1; Theophylline; Triazoles	2014
Dependence of tablet brittleness on tensile strength and porosity. International journal of pharmaceutics, 2015, Sep-30, Volume: 493, Issue:1-2 Topics: Amlodipine; Cellulose; Drugs, Chinese Herbal; Glyburide; Ibuprofen; Porosity; Powders; Salvia miltiorrhiza; Sildenafil Citrate; Silicon Dioxide; Stearic Acids; Tablets; Tensile Strength; Theophylline	2015