theophylline and fluvoxamine

theophylline has been researched along with fluvoxamine in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (25.00)	18.2507
2000's	10 (41.67)	29.6817
2010's	6 (25.00)	24.3611
2020's	2 (8.33)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brøsen, K; Loft, S; Lykkesfeldt, J; Maënpää, J; Pelkonen, O; Poulsen, HE; Rasmussen, BB	1
Harrington, L; van den Brekel, AM	1
Brøsen, K; Loft, S; Poulsen, HE; Rasmussen, BB; Skjelbo, E	1
Brøsen, K; Gaist, D; Jeppesen, U; Rasmussen, BB	1
DeVane, CL; Gill, HS; Hardesty, SJ; Markowitz, JS; Mundy, S	1
Dahlqvist, R; Hägg, S; Söderström, E; Spigset, O	1
Anttila, M; Karnani, H; Nyman, L; Pelkonen, O; Salonen, JS; Taavitsainen, P	1
Arand, M; Friedberg, T; Härtter, S; Hiemke, C; Oesch, F; Wang, X; Weigmann, H	1
Kharasch, ED; Kunze, KL; Levy, RH; Ragueneau, I; Trager, WF; Wang, Y; Yao, C	1
De Martin, S; Orlando, R; Padrini, R; Palatini, P; Perazzi, M; Piccoli, P	1
Brumand, K; Deemyad, T; Malihi, G; Pousti, A	1
Bergstrom, RF; Chappell, J; Hong, Q; Knadler, MP; Lobo, ED; Quinlan, T; Reddy, S; Ring, B	1
Gagne, JJ; Maio, V; Rabinowitz, C	1
De Martin, S; Orlando, R; Palatini, P; Pegoraro, P	1
Bangh, SA; Cole, JB; Meiners, RB	1
Chen, AC; Chen, HY; Cheng, HC; Kao, LT; Lee, IJ; Lu, CK; Tsai, KC; Ueng, YF; Wang, HJ	1

Reviews

2 review(s) available for theophylline and fluvoxamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Enzyme inhibition and induction in liver disease. Current clinical pharmacology, 2008, Volume: 3, Issue:1 Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Fluvoxamine; Humans; Lidocaine; Liver; Liver Diseases; Theophylline	2008

Trials

5 trial(s) available for theophylline and fluvoxamine

Article	Year
Griseofulvin and fluvoxamine interactions with the metabolism of theophylline. Therapeutic drug monitoring, 1997, Volume: 19, Issue:1 Topics: Adult; Antifungal Agents; Bronchodilator Agents; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Drug Interactions; Fluvoxamine; Griseofulvin; Humans; Male; Selective Serotonin Reuptake Inhibitors; Theophylline	1997
Lack of correlation between fluvoxamine clearance and CYP1A2 activity as measured by systemic caffeine clearance. European journal of clinical pharmacology, 1999, Volume: 54, Issue:12 Topics: Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Interactions; Fluvoxamine; Humans; Male; Selective Serotonin Reuptake Inhibitors; Theophylline	1999
Fluvoxamine-theophylline interaction: gap between in vitro and in vivo inhibition constants toward cytochrome P4501A2. Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:5 Topics: Adult; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Drug Interactions; Enzyme Inhibitors; Fluvoxamine; Humans; In Vitro Techniques; Theophylline	2001
Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2-mediated theophylline metabolism by fluvoxamine. Clinical pharmacology and therapeutics, 2006, Volume: 79, Issue:5 Topics: Adult; Antidepressive Agents; Bronchodilator Agents; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Double-Blind Method; Fluvoxamine; Humans; Liver Cirrhosis; Middle Aged; Severity of Illness Index; Theophylline	2006
In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine. Clinical pharmacokinetics, 2008, Volume: 47, Issue:3 Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Interactions; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Infusions, Intravenous; Male; Microsomes, Liver; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Theophylline; Thiophenes	2008

Other Studies

17 other study(ies) available for theophylline and fluvoxamine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine. British journal of clinical pharmacology, 1995, Volume: 39, Issue:2 Topics: Antidepressive Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Fluvoxamine; Humans; In Vitro Techniques; Microsomes, Liver; Selective Serotonin Reuptake Inhibitors; Theophylline	1995
Toxic effects of theophylline caused by fluvoxamine. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1994, Nov-01, Volume: 151, Issue:9 Topics: Aged; Drug Interactions; Female; Fluvoxamine; Humans; Lung Diseases, Obstructive; Nausea; Theophylline	1994
Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6 Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Fluvoxamine; Humans; Imipramine; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenacetin; Theophylline	1993
Fluvoxamine-induced theophylline toxicity. The American journal of psychiatry, 1997, Volume: 154, Issue:9 Topics: Adult; Comorbidity; Depressive Disorder; Drug Interactions; Female; Fluvoxamine; Half-Life; Health Care Costs; Humans; Lung Diseases, Obstructive; Theophylline	1997
Selegiline metabolism and cytochrome P450 enzymes: in vitro study in human liver microsomes. Pharmacology & toxicology, 2000, Volume: 86, Issue:5 Topics: Amphetamines; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluvoxamine; Humans; Ketoconazole; Methamphetamine; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Selegiline; Theophylline	2000
Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin. Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:2 Topics: Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP1A2; Enzyme Inhibitors; Fluvoxamine; Humans; Melatonin; Microsomes, Liver; Serotonin; Theophylline	2001
A preliminary study on the interaction of fluvoxamine and adenosine receptor on isolated Guinea-pig atria. The International journal of neuroscience, 2006, Volume: 116, Issue:12 Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Atropine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluvoxamine; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pilot Projects; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Theophylline; Xanthines	2006
Prevalence and predictors of potential drug-drug interactions in Regione Emilia-Romagna, Italy. Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:2 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Aminophylline; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Child; Child, Preschool; Ciprofloxacin; Drug Interactions; Drug Utilization; Female; Fluvoxamine; Humans; Italy; Male; Middle Aged; Outpatients; Theophylline; Warfarin	2008
Fluvoxamine used to treat COVID-19 resulting in theophylline toxicity from CYP 1A2 drug-drug interaction. Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:8 Topics: COVID-19 Drug Treatment; Cytochrome P-450 CYP1A2; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fluvoxamine; Humans; Theophylline	2022
Identification of the perpetrator imperatorin in Xin-yi-san-theophylline interaction: observed and predicted herb-drug interaction in rats. The Journal of pharmacy and pharmacology, 2023, Sep-01, Volume: 75, Issue:9 Topics: Animals; Bronchodilator Agents; Fluvoxamine; Herb-Drug Interactions; Humans; Rats; Theophylline	2023