theophylline and ethosuximide

theophylline has been researched along with ethosuximide in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's3 (15.79)18.2507
2000's3 (15.79)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE1
Campbell, DJ; Godolphin, W; Urquhart, N1
Rane, A; Wilson, JT1
Dean, PM; Edwardson, JM1
Bachmann, KA; Madhira, MS; Rankin, GO1
Baty, C; Jambou, J; Leducq, B; Richard, L1
Bachmann, KA; Jauregui, L; Martin, M; Schwartz, J; Sullivan, TJ1
Haven, GT; Kiser, EJ; Studts, D1
Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S1
Putnam, RS; Quattrone, AJ1
Bachmann, KA; Jauregui, L1

Reviews

1 review(s) available for theophylline and ethosuximide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for theophylline and ethosuximide

ArticleYear
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3

    Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid

1993

Other Studies

17 other study(ies) available for theophylline and ethosuximide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Use of saliva in therapeutic drug monitoring.
    Clinical chemistry, 1977, Volume: 23, Issue:2 PT. 1

    Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline

1977
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
    Clinical chemistry, 1979, Volume: 25, Issue:5

    Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline

1979
Clinical pharmacokinetics in infants and children.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:1

    Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline

1976
Inhibition of alloxan-induced hyperglycaemia by compounds of similar molecular structure.
    Biochemical pharmacology, 1992, Dec-01, Volume: 44, Issue:11

    Topics: Allantoin; Alloxan; Animals; Barbiturates; Blood Glucose; Caffeine; Ethosuximide; Hyperglycemia; Inositol; Male; Mice; Phenytoin; Structure-Activity Relationship; Theophylline; Uric Acid

1992
The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:1

    Topics: Animals; Antipyrine; Cobalt; Ethosuximide; Liver; Male; Mixed Function Oxygenases; Proadifen; Quinidine; Rats; Rats, Inbred Strains; Succinimides; Theophylline

1992
[Plasma determination of 7 common drugs by high performance liquid chromatography].
    Annales de biologie clinique, 1989, Volume: 47, Issue:2

    Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid

1989
Use of three probes to assess the influence of sex on hepatic drug metabolism.
    Pharmacology, 1987, Volume: 35, Issue:2

    Topics: Adult; Ethosuximide; Female; Humans; Kinetics; Liver; Male; Middle Aged; Phenytoin; Sex Factors; Theophylline

1987
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:3

    Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline

1983
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
    Clinical chemistry, 1980, Volume: 26, Issue:7

    Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline

1980
A single liquid-chromatographic procedure for therapeutic monitoring of theophylline, acetaminophen, or ethosuximide.
    Clinical chemistry, 1981, Volume: 27, Issue:1

    Topics: Acetaminophen; Blood Chemical Analysis; Buffers; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Theophylline

1981