theophylline and duloxetine hydrochloride

theophylline has been researched along with duloxetine hydrochloride in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bergstrom, RF; Chappell, J; Hong, Q; Knadler, MP; Lobo, ED; Quinlan, T; Reddy, S; Ring, B	1
Erve, JC; Vashishtha, SC; Wu, G	1

Trials

1 trial(s) available for theophylline and duloxetine hydrochloride

Article	Year
In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine. Clinical pharmacokinetics, 2008, Volume: 47, Issue:3 Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Interactions; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Infusions, Intravenous; Male; Microsomes, Liver; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Theophylline; Thiophenes	2008

Article

Year

In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine.

Clinical pharmacokinetics, 2008, Volume: 47, Issue:3

Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Cytochrome P-450 CYP1A2; Drug Interactions; Duloxetine Hydrochloride; Female; Fluvoxamine; Humans; Infusions, Intravenous; Male; Microsomes, Liver; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Theophylline; Thiophenes

2008

Other Studies

2 other study(ies) available for theophylline and duloxetine hydrochloride

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs. Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8 Topics: Animals; Binding Sites; Cytosol; Drug Design; Duloxetine Hydrochloride; Glutathione; Glutathione Transferase; Humans; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Quinidine; Rationalization; Rats; Structure-Activity Relationship; Theophylline; Thiophenes	2010

Article

Year

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013

Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs.

Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8

Topics: Animals; Binding Sites; Cytosol; Drug Design; Duloxetine Hydrochloride; Glutathione; Glutathione Transferase; Humans; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Quinidine; Rationalization; Rats; Structure-Activity Relationship; Theophylline; Thiophenes

2010