theophylline and diphenhydramine hydrochloride

theophylline has been researched along with diphenhydramine hydrochloride in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199017 (43.59)18.7374
1990's13 (33.33)18.2507
2000's2 (5.13)29.6817
2010's7 (17.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Forsberg, K; Karlsson, JA; Persson, CG; Zackrisson, C1
Kuribara, H; Tadokoro, S1
Cirillo, R; Franzone, JS; Reboani, MC1
Biglione, V; Cirillo, R; Franzone, JS; Reboani, MC1
Cravanzola, C; Franzone, JS; Grosa, G1
Armstrong, D; Loosmore, S1
Bizzarri, M; Lagana, A; Mancini, M; Marino, A1
Bagnato, G; Bottari, M; Fodale, P1
Biffignandi, P; Franzone, JS; Grossi, E1
Prueter, JC; Sherding, RG1
Jackson, RH; Salem, H1
Renovanz, HD2
Jllig, H1
Weuta, H2
Chodosh, S1
Simon, L; Simonné Talpas, G; Vinkler, E1
Worth, H1
Cochrane, M; Henry, J; Mant, T1
Di Carlo, R; Fonzo, D; Franzone, JS; Reboani, C1
Alexander, MR; Dull, WL; Kasik, J; Mustion, AL; Taylor, JW1
Braghiroli, A; Donner, CF; Grossi, E; Sacco, C1
Joki, S; Korbonits, D; Minker, E; Nuutinen, J; Saano, V; Virta, P1
De Maria, P; Galimberti, M; Ronchi, E; Villani, F1
Checchini, M; Franzini, C; Magni, M; Omboni, E; Scaglione, M; Vaccarella, A1
Arányi, P; Boér, K; Boronkay, E; Gyürky, J; Kapui, Z; Korbonits, D; Lacheretz, F; Mikus, EG; Pascal, M; Révész, J1
Guo, H; He, LY; Huang, JH; Xu, XY1
LESPAGNOL, A; LESPAGNOL, C1
GILBERT, J; ISRAUEL-ASSELAIN, R1
El-Gindy, A; Emara, S; Mostafa, A1
Mokry, J; Nosalova, G1
Adcock, JJ; Belvisi, MG; Birrell, MA; Dubuis, E; Grace, MS; Maher, SA; Wortley, MA1
Fraňová, S; Jošková, M; Kazimierová, I; Pecháňová, O; Šutovská, M1
Naveed, S; Rehman, H; Usmanghani, K1

Reviews

5 review(s) available for theophylline and diphenhydramine hydrochloride

ArticleYear
[Doxofylline: pharmacologic profile and a review of clinical studies].
    Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques, 1988, Volume: 10, Issue:5

    Topics: Animals; Antitussive Agents; Humans; Theophylline

1988
Canine chronic bronchitis.
    The Veterinary clinics of North America. Small animal practice, 1985, Volume: 15, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Antitussive Agents; Bronchitis; Bronchodilator Agents; Chronic Disease; Dog Diseases; Dogs; Drug Therapy, Combination; Expectorants; Theophylline

1985
Oral theophylline preparations--a review of their clinical efficacy in the treatment of bronchial asthma.
    Annals of allergy, 1974, Volume: 32, Issue:4

    Topics: Acute Disease; Administration, Oral; Adrenal Cortex Hormones; Antacids; Antitussive Agents; Asthma; Barbiturates; Bronchodilator Agents; Capsules; Chronic Disease; Drug Combinations; Drug Evaluation; Expectorants; Histamine H1 Antagonists; Humans; Potassium Iodide; Solutions; Tablets; Theophylline

1974
Newer drugs in the treatment of chronic bronchitis.
    The Medical clinics of North America, 1967, Volume: 51, Issue:5

    Topics: Acetylcysteine; Ampicillin; Anti-Bacterial Agents; Antitussive Agents; Bronchitis; Chronic Disease; Expectorants; Glycerol; Guaiacol; Humans; Methacycline; Peptide Hydrolases; Propylamines; Sulfadimethoxine; Sulfonamides; Theophylline; Thiazines

1967
Therapy of chronic obstructive airways disease.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antitussive Agents; Asthma; Expectorants; Humans; Lung Diseases, Obstructive; Oxygen; Respiratory Function Tests; Sympathomimetics; Theophylline

1984

Trials

9 trial(s) available for theophylline and diphenhydramine hydrochloride

ArticleYear
[Clinical evaluation of doxofylline sachets in a pediatric population].
    Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques, 1989, Volume: 11, Issue:4

    Topics: Antitussive Agents; Child; Double-Blind Method; Female; Humans; Male; Randomized Controlled Trials as Topic; Respiratory Function Tests; Respiratory Tract Diseases; Theophylline

1989
[Clinical pharmacology in the domain of pulmonology].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:4

    Topics: Acetylcholine; Adrenal Cortex Hormones; Aerosols; Antitussive Agents; Asthma; Bronchodilator Agents; Carbon Dioxide; Central Nervous System Stimulants; Citrates; Clinical Trials as Topic; Cough; Expectorants; Humans; Hydrocortisone; Isoproterenol; Lobeline; Lung Diseases; Metaproterenol; Oxygen; Pharmacology; Placebos; Spirometry; Theophylline

1970
[Clinical pharmacology in the domain of pulmonology].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:4

    Topics: Acetylcholine; Adrenal Cortex Hormones; Aerosols; Antitussive Agents; Asthma; Bronchodilator Agents; Carbon Dioxide; Central Nervous System Stimulants; Citrates; Clinical Trials as Topic; Cough; Expectorants; Humans; Hydrocortisone; Isoproterenol; Lobeline; Lung Diseases; Metaproterenol; Oxygen; Pharmacology; Placebos; Spirometry; Theophylline

1970
[Clinical investigation of a combination preparation of ampicillin, theophylline, papaverine-HCl and guaiacolglyceryl ether. 1. In form of tablets].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Acute Disease; Adult; Ampicillin; Antitussive Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Electronic Data Processing; Female; Guaifenesin; Humans; Male; Medical Records; Papaverine; Tablets; Theophylline

1974
[Clinical investigation of a combination preparation of ampicillin, theophylline, papaverine-HCl and guaiacolglyceryl ether. 2. In form of syrup].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Acute Disease; Adolescent; Ampicillin; Antitussive Agents; Auscultation; Bronchitis; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Dosage Forms; Drug Combinations; Drug Evaluation; Guaifenesin; Humans; Infant; Papaverine; Theophylline

1974
The effects of doxofylline versus theophylline on sleep architecture in COPD patients.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1995, Volume: 50, Issue:2

    Topics: Adult; Aged; Antitussive Agents; Arousal; Cross-Over Studies; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Polysomnography; Single-Blind Method; Sleep; Sleep Stages; Theophylline; Vital Capacity; Wakefulness

1995
Oral doxophylline in patients with chronic obstructive pulmonary disease.
    International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Antitussive Agents; Blood Gas Analysis; Chromatography, High Pressure Liquid; Female; Forced Expiratory Flow Rates; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Respiratory Function Tests; Spirometry; Theophylline; Treatment Outcome

1997
[Controlled clinical study of doxophylline versus aminophylline in the treatment of acute cardiorespiratory insufficiency syndromes].
    Minerva cardioangiologica, 1997, Volume: 45, Issue:4

    Topics: Aminophylline; Antitussive Agents; Bronchodilator Agents; Cardiotonic Agents; Female; Heart Failure; Humans; Male; Middle Aged; Oxygen Consumption; Respiratory Insufficiency; Syndrome; Theophylline

1997
Efficacy and safety of Linkus, Aminophylline diphenhydramine and acefyllin piperazine for the treatment of cough in children.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:3 Suppl

    Topics: Age Factors; Aminophylline; Antitussive Agents; Bronchodilator Agents; Child; Child, Preschool; Cough; Diphenhydramine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Pakistan; Pharyngitis; Sleep; Sleep Wake Disorders; Theophylline; Time Factors; Treatment Outcome

2016

Other Studies

25 other study(ies) available for theophylline and diphenhydramine hydrochloride

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Selective inhibition of cough and bronchoconstriction in conscious guinea pigs.
    Respiration; international review of thoracic diseases, 1992, Volume: 59, Issue:2

    Topics: Animals; Antitussive Agents; Bronchoconstriction; Bronchodilator Agents; Citrates; Citric Acid; Cough; Female; Guinea Pigs; Ipratropium; Lidocaine; Male; Terbutaline; Theophylline; Xanthines

1992
[Behavioral study on reduction of psychotic and behavioral disorders induced by antitussive and expectorant].
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1992, Volume: 27, Issue:2

    Topics: Animals; Antitussive Agents; Avoidance Learning; Behavior, Animal; Caffeine; Expectorants; Male; Mice; Mice, Inbred Strains; Motor Activity; Psychoses, Substance-Induced; Theophylline

1992
Pharmacological studies in animals of beta-hydroxyethyltheophylline, the major metabolite of doxofylline in humans.
    Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Animals; Antitussive Agents; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Electrocardiography; Epinephrine; Female; Guinea Pigs; Humans; Ileum; Lethal Dose 50; Male; Movement; Muscle Contraction; Muscle, Smooth; Rabbits; Rats; Receptors, Purinergic; Serotonin; Stimulation, Chemical; Theophylline; Trachea; Vagus Nerve

1991
Pharmacological and toxicological activities of a new methylxanthine derivative [7-(1,3-dithiolan-2-ylmethyl)1,3-dimethylxanthine] with antibronchospastic and mucoregulatory properties.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminophylline; Animals; Antitussive Agents; Asthma; Bronchial Spasm; Diuretics; Gastric Acidity Determination; Guinea Pigs; Mice; Rabbits; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline

1990
Kinetic and metabolic studies of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine in the rat.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:6

    Topics: Absorption; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Bronchial Spasm; Male; Rats; Rats, Inbred Strains; Theophylline; Tissue Distribution

1990
Do-Do abuse.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Adult; Antitussive Agents; Caffeine; Drug Combinations; Ephedrine; Female; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline

1990
Solid phase extraction and high performance liquid chromatographic determination of doxophylline in plasma.
    Biomedical chromatography : BMC, 1990, Volume: 4, Issue:5

    Topics: Adult; Antitussive Agents; Chromatography, High Pressure Liquid; Female; Humans; Indicators and Reagents; Male; Spectrophotometry, Ultraviolet; Theophylline

1990
[Drug therapy of asthma and bronchitis].
    Deutsches medizinisches Journal, 1971, Apr-19, Volume: 22, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Antitussive Agents; Asthma; Bronchitis; Humans; Hypnotics and Sedatives; Sympathomimetics; Theophylline

1971
[Simultaneous determination of papaverine hydrochloride throphylline and azophen in powder mixture].
    Acta pharmaceutica Hungarica, 1969, Volume: 39, Issue:6

    Topics: Antitussive Agents; Barbiturates; Bronchodilator Agents; Papaverine; Phenacetin; Theophylline

1969
[Long-term therapy of bronchial asthma].
    Fortschritte der Medizin, 1983, Mar-24, Volume: 101, Issue:11

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Bacterial Agents; Antitussive Agents; Asthma; Child; Expectorants; Humans; Long-Term Care; Sympathomimetics; Theophylline

1983
ABC of poisoning. Respiratory drugs.
    British medical journal (Clinical research ed.), 1984, Oct-27, Volume: 289, Issue:6452

    Topics: Acute Disease; Adrenergic beta-Agonists; Antitubercular Agents; Antitussive Agents; Bronchodilator Agents; Child; Humans; Infant, Newborn; Parasympatholytics; Respiratory Tract Diseases; Theophylline

1984
Pharmacological researches on 2-(7'-theophyllinemethyl)1,3-dioxolane.
    Il Farmaco; edizione scientifica, 1981, Volume: 36, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Anesthetics, Local; Animals; Antitussive Agents; Bronchial Spasm; Central Nervous System; Gastrointestinal Motility; Guinea Pigs; Hemodynamics; In Vitro Techniques; Muscle, Smooth; Rabbits; Theophylline

1981
Influence of chinoin-170, a novel antitussive, on the mucociliary activity in respiratory airways of rats, rabbits, guinea-pigs and man.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:9

    Topics: Animals; Antitussive Agents; Cilia; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Injections, Intravenous; Male; Mucociliary Clearance; Oxadiazoles; Rabbits; Rats; Rats, Wistar; Theophylline; Trachea

1993
Experimental studies on the antitussive properties of the new xanthine derivative 1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]. 2nd communication: investigations on theophylline-like activities.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:12

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Antitussive Agents; Autonomic Nervous System; Bronchodilator Agents; Electrophysiology; Female; Guinea Pigs; Hemodynamics; Histamine Antagonists; In Vitro Techniques; Male; Oxadiazoles; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Respiratory Mechanics; Theophylline

1997
[Preliminary study on the absorption, distribution and excretion of doxophylline in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:2

    Topics: Absorption; Animals; Antitussive Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Male; Rats; Rats, Wistar; Theophylline; Tissue Distribution

1997
[Recent therapeutic acquisitions related to chemical synthesis].
    Produits pharmaceutiques, 1963, Volume: 18

    Topics: Analgesics; Analgesics, Non-Narcotic; Anticoagulants; Antipyretics; Antitussive Agents; Cardiovascular Agents; Lipotropic Agents; Monoamine Oxidase Inhibitors; Muscle Relaxants, Central; Theophylline; Vasodilator Agents

1963
[TREATMENT AND PREVENTION OF CHRONIC DYSPNEIC BRONCHITIS].
    Le Poumon et le coeur, 1964, Volume: 20

    Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitussive Agents; Atropine; Balneology; Bronchitis; Bronchitis, Chronic; Chymotrypsin; Climate; Cortisone; Cysteine; Dyspnea; Ephedrine; Exercise Therapy; Heart Diseases; Humans; Hydrocortisone; Hypnotics and Sedatives; Theophylline; Trypsin; Vaccination

1964
Application and validation of chemometrics-assisted spectrophotometry and liquid chromatography for the simultaneous determination of six-component pharmaceuticals.
    Journal of pharmaceutical and biomedical analysis, 2006, May-03, Volume: 41, Issue:2

    Topics: Antitussive Agents; Bronchodilator Agents; Chromatography, High Pressure Liquid; Complex Mixtures; Diphenhydramine; Expectorants; Guaifenesin; Least-Squares Analysis; Parabens; Preservatives, Pharmaceutical; Principal Component Analysis; Reproducibility of Results; Sodium Benzoate; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Theophylline

2006
The influence of the PDE inhibitors on cough reflex in guinea pigs.
    Bratislavske lekarske listy, 2011, Volume: 112, Issue:3

    Topics: Animals; Antitussive Agents; Bronchial Hyperreactivity; Citric Acid; Cough; Guinea Pigs; Male; Ovalbumin; Phosphodiesterase Inhibitors; Reflex; Theobromine; Theophylline

2011
Theophylline inhibits the cough reflex through a novel mechanism of action.
    The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:6

    Topics: Action Potentials; Animals; Antitussive Agents; Calcium; Capsaicin; Cough; Disease Models, Animal; Ganglia, Sensory; Guinea Pigs; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Male; Nerve Fibers, Unmyelinated; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Reflex; Sensory Receptor Cells; Small-Conductance Calcium-Activated Potassium Channels; Theophylline; Vagus Nerve

2014
Effects of provinol and its combinations with clinically used antiasthmatics on airway defense mechanisms in experimental allergic asthma.
    Advances in experimental medicine and biology, 2015, Volume: 838

    Topics: Administration, Inhalation; Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Antitussive Agents; Asthma; Bronchodilator Agents; Budesonide; Drug Synergism; Drug Therapy, Combination; Guinea Pigs; Injections, Intraperitoneal; Lung; Male; Muscle, Smooth; Ovalbumin; Polyphenols; Theophylline; Tissue Culture Techniques

2015