theophylline and debrisoquin

theophylline has been researched along with debrisoquin in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (40.00)	18.7374
1990's	1 (10.00)	18.2507
2000's	4 (40.00)	29.6817
2010's	1 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Birkett, DJ; Miners, JO; Wing, LM	1
Bounameaux, Y	1
Palkoski, Z; Pettinger, W; Renyi, E; Sheppard, H	1
Bertilsson, L; Birkett, DJ; Dahlqvist, R; Eichelbaum, M; Säwe, J; Sjöqvist, F	1
Lewis, IA; Palmer, J; Pleasance, S; Scott, RJ	1
Adedoyin, A; Branch, RA; Frye, RF; Romkes, M; Wilson, JW	1
Branch, RA; Chaves-Gnecco, D; Frye, RF; Matzke, GR; Rabinovitz, M; Shaikh, OS; Zgheib, NK	1
Fuhr, U; Jetter, A; Kirchheiner, J	1

Reviews

1 review(s) available for theophylline and debrisoquin

Article	Year
Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in humans and their simultaneous use in the "cocktail" approach. Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:2 Topics: Administration, Oral; ATP-Binding Cassette Transporters; Caffeine; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Pharmaceutical Preparations; Phenotype; Theophylline; Tolbutamide	2007

Article

Year

Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in humans and their simultaneous use in the "cocktail" approach.

Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:2

Topics: Administration, Oral; ATP-Binding Cassette Transporters; Caffeine; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Pharmaceutical Preparations; Phenotype; Theophylline; Tolbutamide

2007

Trials

1 trial(s) available for theophylline and debrisoquin

Article	Year
Liver disease selectively modulates cytochrome P450--mediated metabolism. Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3 Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoenzymes; Liver Diseases; Male; Mephenytoin; Middle Aged; Muscle Relaxants, Central; Phosphodiesterase Inhibitors; Severity of Illness Index; Theophylline	2006

Article

Year

Liver disease selectively modulates cytochrome P450--mediated metabolism.

Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoenzymes; Liver Diseases; Male; Mephenytoin; Middle Aged; Muscle Relaxants, Central; Phosphodiesterase Inhibitors; Severity of Illness Index; Theophylline

2006

Other Studies

8 other study(ies) available for theophylline and debrisoquin

Article	Year
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Normal metabolism of debrisoquine and theophylline in a slow tolbutamide metaboliser. Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:3 Topics: Adult; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Isoenzymes; Isoquinolines; Male; Theophylline; Tolbutamide	1985
[Studies on the effect of various substances on platelet function with several methods]. Die Medizinische Welt, 1973, Feb-02, Volume: 24, Issue:5 Topics: Amphetamine; Anti-Anxiety Agents; Blood Platelets; Caffeine; Chlorpromazine; Debrisoquin; Dibenzazepines; Flurazepam; Guanethidine; Humans; Oxazoles; Papaverine; Phenytoin; Platelet Aggregation; Pyridines; Theophylline	1973
Angiotensin antagonism and antihypertensive activity of phosphodiesterase inhibiting agents. Life sciences. Pt. 1: Physiology and pharmacology, 1973, Jan-15, Volume: 12, Issue:2 Topics: Adult; Angiotensin II; Animals; Bethanechol Compounds; Blood Pressure; Bradykinin; Bretylium Compounds; Debrisoquin; Diazoxide; Dose-Response Relationship, Drug; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Imidazoles; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Phosphodiesterase Inhibitors; Rats; Theophylline; Vasodilator Agents	1973
Theophylline metabolism in relation to antipyrine, debrisoquine, and sparteine metabolism. Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:6 Topics: Adult; Antipyrine; Debrisoquin; Female; Humans; Isoquinolines; Male; Metabolic Clearance Rate; Middle Aged; Phenotype; Saliva; Smoking; Sparteine; Theophylline	1984
Determination of a 'GW cocktail' of cytochrome P450 probe substrates and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry. Rapid communications in mass spectrometry : RCM, 1999, Volume: 13, Issue:23 Topics: Automation; Caffeine; Chlorzoxazone; Chromatography, Gas; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Debrisoquin; Diclofenac; Glucuronidase; Humans; Indicators and Reagents; Midazolam; Reproducibility of Results; Sensitivity and Specificity; Substrate Specificity; Theophylline	1999
In vivo modulation of CYP enzymes by quinidine and rifampin. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:4 Topics: Acetylation; Administration, Oral; Adrenergic alpha-Antagonists; Adult; Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Enzyme Inhibitors; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Quinidine; Reference Values; Rifampin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline	2000