theophylline has been researched along with cyclosporine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (33.33) | 18.2507 |
| 2000's | 14 (33.33) | 29.6817 |
| 2010's | 14 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Elkamhawy, A; Hassan, AHE; Lee, J; Moon, B; Pae, AN; Park, BG; Park, HM; Park, JE; Ra, H; Roh, EJ | 1 |
| Bigler, S; Hänseler, E; Wad, N | 1 |
| Carey, D; Lee, HS; Tett, S | 1 |
| Klotz, U; Kroemer, HK | 1 |
| French, MT; Miller, JN; Palmer, DA | 1 |
| Hossain, M; Okubo, Y; Sekiguchi, M | 1 |
| Cambar, J; L'Azou, B; Lakhdar, B; Potier, M | 1 |
| Emery, DL; McClure, SJ | 1 |
| Kudoh, S; Satoh, A | 1 |
| Afargan, M; Hoffman, A; Pinto, E; Schattner, A | 1 |
| Bia, MJ; Perazella, MA | 1 |
| Hortin, GL; Landt, M; Smith, CH | 1 |
| Barnes, PJ | 1 |
| Aparicio, M; Cambar, J; Potier, M | 1 |
| Pons, G; Rey, E; Tréluyer, JM | 1 |
| Gouyon, JB; Guignard, JP; Justrabo, E; Prévot, A; Semama, DS; Tendron, A | 1 |
| Athanaselis, S; Dona, A; Koutselinis, A; Maravelias, C | 1 |
| Madsen, SS; Tipsmark, CK | 1 |
| Akdis, CA; Akdis, M; Blaser, K; Bröcker, EB; Disch, R; Schmid-Grendelmeier, P; Trautmann, A | 1 |
| Gouyon, JB; Guignard, JP; Justrabo, E; Liet, JM; Prévot, A; Semama, DS | 1 |
| Arlett, P; Bergquist, C; Gerden, B; Henderson, L; Yue, QY | 1 |
| Savage, N; Uboldi, AD | 1 |
| Lal, SM; Trivedi, H | 1 |
| Echizen, H; Kanamori, M; Takahashi, H | 1 |
| Aarabi, M; Allabi, AC; Almond, LM; Ghobadi, C; Jamei, M; Johnson, TN; Rostami-Hodjegan, A; Rowland-Yeo, K | 1 |
| Dahlgren, D; Lennernäs, H; Roos, C; Sjögren, E | 1 |
| Hodge, G; Hodge, S; Holmes, M; Jersmann, H; Reynolds, PN; Roscioli, E; Tran, HB | 1 |
6 review(s) available for theophylline and cyclosporine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The drug interaction potential of ranitidine: an update.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Cyclosporine; Drug Interactions; Humans; Psychotropic Drugs; Ranitidine; Theophylline | 1991 |
Posttransplant erythrocytosis: case report and review of newer treatment modalities.
Topics: Blood Volume; Bloodletting; Combined Modality Therapy; Cyclosporine; Diabetic Nephropathies; Diuretics; Erythrocyte Volume; Erythropoietin; Feedback; Humans; Iron Deficiencies; Kidney Transplantation; Male; Middle Aged; Polycythemia; Postoperative Complications; Theophylline | 1993 |
Immunomodulation as asthma therapy: where do we stand?
Topics: Adjuvants, Immunologic; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Bacterial Agents; Antibodies, Monoclonal; Asthma; Bronchodilator Agents; Cell Adhesion; Cromolyn Sodium; Cyclosporine; Cytokines; Gold; Humans; Immunoglobulin G; Immunosuppressive Agents; Macrolides; Methotrexate; Nedocromil; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Theophylline | 1996 |
Drug disposition in cystic fibrosis.
Topics: Absorption; Anti-Infective Agents; Ciprofloxacin; Cloxacillin; Cyclosporine; Cystic Fibrosis; Fleroxacin; Humans; Theophylline; Tissue Distribution | 1998 |
St John's wort (Hypericum perforatum): drug interactions and clinical outcomes.
Topics: Contraceptives, Oral; Cyclosporine; Digoxin; Drug Interactions; Herb-Drug Interactions; HIV Protease Inhibitors; Humans; Hypericum; Plant Extracts; Selective Serotonin Reuptake Inhibitors; Theophylline; Warfarin | 2002 |
2 trial(s) available for theophylline and cyclosporine
| Article | Year |
|---|---|
Analyses of the pattern of therapeutic drug monitoring in a university hospital laboratory. Suitability and performance of the CEDIA assays.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1992 |
A prospective, randomized, open labeled crossover trial of fosinopril and theophylline in post renal transplant erythrocytosis.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Azathioprine; Biomarkers; Blood Pressure; Blood Urea Nitrogen; Creatinine; Cross-Over Studies; Cyclosporine; Fosinopril; Hematocrit; Hemoglobins; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Polycythemia; Postoperative Complications; Potassium; Prednisone; Prospective Studies; Theophylline; Treatment Outcome; Vasodilator Agents | 2003 |
34 other study(ies) available for theophylline and cyclosporine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Drug Discovery; Hippocampus; Immunosuppressive Agents; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Molecular Docking Simulation; Neurons; Piperazines; Protein Conformation; Urea | 2017 |
Drug interactions with fluconazole.
Topics: Cross-Sectional Studies; Cyclosporine; Drug Interactions; Fluconazole; Humans; Phenytoin; Theophylline; Warfarin | 1992 |
Flow injection immunoassay using a protein A immunoreactor.
Topics: Cyclosporine; Electrochemistry; Flow Injection Analysis; Immunoassay; Spectrometry, Fluorescence; Staphylococcal Protein A; Theophylline | 1991 |
Effects of various drugs (staurosporine, herbimycin A, ketotifen, theophylline, FK506 and cyclosporin A) on eosinophil viability.
Topics: Alkaloids; Asthma; Benzoquinones; Cell Survival; Cyclosporine; Eosinophils; Humans; Ketotifen; Lactams, Macrocyclic; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Staurosporine; Tacrolimus; Theophylline | 1994 |
Evidence for a protective effect of theophylline and caffeine on cyclosporine-induced contractions in two in vitro glomerular models.
Topics: Animals; Caffeine; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Mesangium; In Vitro Techniques; Kidney Glomerulus; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Theophylline; Time Factors | 1995 |
Studies on the inhibition of rejection of Trichostrongylus colubriformis larvae from immune sheep.
Topics: Animals; Azepines; Chlorpheniramine; Cyclosporine; Dexamethasone; Indomethacin; Larva; Piroxicam; Rejection, Psychology; Sheep; Sheep Diseases; Theophylline; Triazoles; Trichostrongylosis; Trichostrongylus | 1995 |
[Basic studies on the prevention of cyclosporin A induced nephrotoxicity].
Topics: Animals; Cyclosporine; Diltiazem; Humans; Kidney; Kidney Diseases; Lymphocyte Activation; Male; Rats; Rats, Wistar; Theophylline | 1994 |
Cyclosporine enhances theophylline neurotoxicity in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Cyclosporine; Drug Synergism; Female; Injections, Intravenous; Nervous System Diseases; Rats; Seizures; Theophylline | 1994 |
Evaluation of evacuated blood-collection tubes: effects of three types of polymeric separators on therapeutic drug-monitoring specimens.
Topics: Acrylic Resins; Blood Specimen Collection; Cell Separation; Cyclosporine; Digoxin; Drug Monitoring; Ethanol; Gentamicins; Humans; Phenobarbital; Phenytoin; Polyesters; Polymers; Silicones; Theophylline | 1993 |
Protective effect of three xanthine derivatives (theophylline, caffeine and pentoxifylline) against the cyclosporin A-induced glomerular contraction in isolated glomeruli and cultured mesangial cells.
Topics: Animals; Caffeine; Cells, Cultured; Cyclosporine; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Immunosuppressive Agents; In Vitro Techniques; Kidney Glomerulus; Male; Muscle Contraction; Pentoxifylline; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1997 |
Endothelin, angiotensin II and adenosine in acute cyclosporine A nephrotoxicity.
Topics: Acute Disease; Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclosporine; Endothelins; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Perindopril; Rabbits; Renal Circulation; Theophylline; Vascular Resistance; Water | 2000 |
The importance of performing in vitro cytotoxicity testing before immunomodulation evaluation.
Topics: Antineoplastic Agents, Hormonal; Cadmium Chloride; Colorimetry; Cyclosporine; Cytotoxicity Tests, Immunologic; Dexamethasone; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Lymphocytes; Quaternary Ammonium Compounds; Theophylline; Vasodilator Agents | 2000 |
Rapid modulation of Na+/K+-ATPase activity in osmoregulatory tissues of a salmonid fish.
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclosporine; Enzyme Inhibitors; Fresh Water; Gills; In Vitro Techniques; Kidney; Okadaic Acid; Ouabain; Phosphodiesterase Inhibitors; Rubidium Radioisotopes; Seawater; Sodium-Potassium-Exchanging ATPase; Theophylline; Trout | 2001 |
Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis.
Topics: Acute Disease; Apoptosis; Cells, Cultured; Cyclosporine; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dexamethasone; fas Receptor; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Interleukin-12; Keratinocytes; Sirolimus; T-Lymphocytes; Tacrolimus; Th1 Cells; Theophylline | 2001 |
Disparate effects of chronic and acute theophylline on cyclosporine A nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Cyclosporine; Drug Administration Schedule; Glomerular Filtration Rate; Immunosuppressive Agents; Male; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 2002 |
The adenylate cyclase activator forskolin partially protects L929 cells against tumour necrosis factor-alpha-mediated cytotoxicity via a cAMP-independent mechanism.
Topics: Adenylyl Cyclases; Cell Death; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cyclosporine; DNA Fragmentation; Humans; Pentoxifylline; Theophylline; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
Developmental changes in the liver weight- and body weight-normalized clearance of theophylline, phenytoin and cyclosporine in children.
Topics: Administration, Oral; Adolescent; Age Factors; Aryl Hydrocarbon Hydroxylases; Body Surface Area; Body Weight; Child; Child, Preschool; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Infant; Infant, Newborn; Liver; Metabolic Clearance Rate; Mixed Function Oxygenases; Models, Biological; Organ Size; Phenytoin; Theophylline | 2002 |
Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.
Topics: Adolescent; Adult; Aged; Benzodiazepines; Body Weights and Measures; Caffeine; Chlorzoxazone; Computer Simulation; Cyclosporine; Female; Gastrointestinal Tract; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Obesity; Obesity, Morbid; Pharmacokinetics; Phenytoin; Regional Blood Flow; Theophylline; Young Adult | 2011 |
Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data.
Topics: Budesonide; Colon; Cyclosporine; Fenofibrate; Humans; Intestinal Absorption; Intestinal Mucosa; Lisdexamfetamine Dimesylate; Metoprolol; Nifedipine; Pyrimidines; Ranitidine; Rivastigmine; Sumatriptan; Terfenadine; Theophylline | 2015 |
Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes.
Topics: Adult; Aged; Case-Control Studies; CD28 Antigens; CD8-Positive T-Lymphocytes; Cellular Senescence; Cyclosporine; Down-Regulation; Enzyme Activation; Enzyme Activators; Female; Histone Acetyltransferases; Histone Deacetylase 2; Humans; Immunosuppressive Agents; Interferon-gamma; Male; Middle Aged; Natural Killer T-Cells; Phenotype; Prednisolone; Pulmonary Disease, Chronic Obstructive; Theophylline; Tumor Necrosis Factor-alpha | 2015 |