theophylline has been researched along with cyclic gmp in 373 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 325 (87.13) | 18.7374 |
| 1990's | 37 (9.92) | 18.2507 |
| 2000's | 6 (1.61) | 29.6817 |
| 2010's | 3 (0.80) | 24.3611 |
| 2020's | 2 (0.54) | 2.80 |
| Authors | Studies |
|---|---|
| Morishima, I | 2 |
| Chatterjee, SK; Kim, U | 1 |
| Garbers, DL; Hardman, JG | 2 |
| Keller, R; Spindler, KD; Willig, A | 1 |
| Ghanbari, H; McCarl, RL | 1 |
| Filburn, CR; Karn, J; Wyatt, GR | 1 |
| Goridis, C; Weller, M | 1 |
| Gopalakrishnan, TV; Thompson, EB | 1 |
| Christian, ST; Monti, JA; Pagel, J; Quayle, ES | 1 |
| Hamilton, J; Horwitz, BA | 1 |
| Chan, YH; Curtis-Prior, PB; Gibbons, JR | 1 |
| Parker, CW; Sullivan, TJ | 1 |
| Birnbaumer, L; Entman, ML; Garber, AJ | 1 |
| Bennett, T; Strange, PG | 1 |
| Brackett, NL; Helfman, DM; Kuo, JF; Shoji, M | 1 |
| Fawcett, CP; McCann, SM; Naor, Z; Snyder, G | 1 |
| Brown, BS; Krzanowski, JJ; Polson, JB | 1 |
| Losier, AJ; YoungLai, EV | 1 |
| Bar-Eli, M; Callily, R; Cohen, H; Wahba, A | 1 |
| Singh, M | 2 |
| Barnes, LD; Dousa, TP; Frohnert, PP; Hui, YS | 1 |
| Bogair, N; Golander, A; Spirer, Z; Zakuth, V | 1 |
| Schreiner, GF; Unanue, ER | 1 |
| Fisher, JW; George, WJ; Rodgers, GM | 1 |
| Mandel, P; Virmaux, N; Weller, M | 1 |
| Asano, T; Hidaka, H; Shimamoto, T | 1 |
| Robison, GA; Thompson, WJ; Van Inwegen, RG | 1 |
| Boynton, AL; Gillan, DJ; Isaacs, RJ; MacManus, JP; Whitfield, JF | 1 |
| Lieberman, I; Rudert, WA; Short, J; Tsukada, K | 1 |
| Bailey, RP; Lieberman, I; Rudert, WA; Short, J | 1 |
| Butcher, FR | 1 |
| Duell, EA; Voorhees, JJ | 1 |
| Cuatrecasas, P | 1 |
| Bach, JF; Bach, MA; Fournier, C | 1 |
| Peart, WS; Quesada, T; Tenyi, I | 1 |
| Ackerman, NR; Beebe, JR | 1 |
| Becker, G; Prasad, KN; Tripathy, K | 1 |
| Minakami, S; Nakagawara, A | 1 |
| Fujimura, S; Sato, S; Sugimura, T; Yoda, K | 1 |
| Minakami, S; Nakagawara, A; Takeshige, K | 1 |
| Denniss, AR; Young, JA | 1 |
| Rillema, JA; Smith, RD | 1 |
| Bourret, LA; Harvey, A; Mensi, T; Rodan, GA | 1 |
| Granger, GA; Prieur, AM | 1 |
| Chauvet, G; Goldstein, I; Hoffstein, S; Robineaux, R; Weissmann, G | 1 |
| Huberman, E; Sachs, L; Yamasaki, H | 1 |
| Rillema, JA | 2 |
| Doskeland, SO; Ueland, PM | 1 |
| Dankner, R; Parker, CW; Wedner, HJ | 1 |
| Schulz, I | 1 |
| Brachet, J; Hubert, E; Kram, R; Schutter, AP | 1 |
| Howell, SL; Montague, W; Tyhurst, M | 1 |
| Gullis, RJ; Rowe, CE | 2 |
| Dickens, MS; Lucas-Leonard, J; Roth, JS | 1 |
| Baird, CE; Hardman, JG; Wells, JN; Wu, YJ | 1 |
| Haymovits, A; Scheele, GA | 1 |
| Koyama, D; Ono, T; Tomida, M | 1 |
| Chayoth, R; DeRubertis, FR; Field, JB | 1 |
| Fawcett, CP; McCann, SM; Sundberg, DK | 1 |
| Granström, E; Malmsten, C; Samuelsson, B | 1 |
| Baker, BI | 1 |
| Huot, J; Jard, S; Penit, J | 1 |
| Anderson, LD; Rillema, JA | 1 |
| Andersson, RG; Arnqvist, HJ; Lundholm, L | 1 |
| Noguchi, Y; Okuda, K; Tadokoro, I; Takahashi, T | 1 |
| Molloy, BB; Ryan, JJ; Schmidt, MJ | 1 |
| Krnjevic, K; Van Meter, WG | 1 |
| Claycomb, WC | 1 |
| Yasunaga, K | 1 |
| Craven, PA; DeRubertis, FR | 1 |
| Davis, BB; Zenser, TV | 1 |
| Kipnis, DM; Pipeleers, DG; Pipeleers-Marichal, MA | 1 |
| Ewald, DA | 1 |
| Furihata, C; Matsushima, T; Sugimura, T; Terai, M | 1 |
| Jarrousse, C; Rosselin, G | 1 |
| Kajishima, T; Takeuchi, YK | 1 |
| Kosher, RA | 1 |
| Erlij, D; Grinstein, S | 1 |
| Lederis, K; Mathison, R | 1 |
| Capps, MJ; Itzhaki, S | 2 |
| Asano, T; Hidaka, H | 1 |
| Kalix, P | 1 |
| Dretchen, KL; Morgenroth, VH; Skirboll, LR; Standaert, FG | 1 |
| Friedman, DL; Johnson, RA; Zeilig, CE | 1 |
| Gerrard, JM; Stoddard, S; Townsend, D; White, JG; Witkop, CJ | 1 |
| Craven, PA; Davis, BB; DeRubertis, FR; Zenser, TV | 1 |
| Christoffersen, T; Wisloff, F | 1 |
| Shimizu, H; Yamamura, Y | 1 |
| Clarenbach, P; Cramer, H; Hammers, R; Lindl, T | 1 |
| Brascher, HK; Ferreira, GG; Javierre, MQ; Lima, AO; Sassine, WA | 1 |
| Kang, ES | 1 |
| Alford, BL; Barnes, EM | 1 |
| Makhlouf, GM; Schebalin, M; Zfass, AM | 1 |
| Heim, F; Mitznegg, P; Sprügel, W | 1 |
| Borysenko, JZ; Karnovsky, MJ; Ukena, TE | 1 |
| Asano, T; Hidaka, H; Ochiai, Y | 1 |
| Saito, M | 1 |
| Daly, JW; Ohga, Y | 1 |
| Atkins, D; Hunt, NH; Ingleton, PM; Martin, TJ | 1 |
| Fremuth, F | 1 |
| Biddulph, DM; Wrenn, RW | 1 |
| Ruoff, HJ | 1 |
| Horn, JP; McAfee, DA | 1 |
| Butcher, FR; Speaker, MG | 1 |
| Giroud, JP; Roch-Arveiller, M | 1 |
| Anderson, RW; Nahmias, AJ; Stanwick, TL | 1 |
| Deporter, DA | 1 |
| Cimo, PL; Gum, JR; Moake, JL; Peterson, DM; Widmer, K | 1 |
| Thomas-Morvan, C | 1 |
| Lindemann, CB | 1 |
| Garbers, DL; Kopf, GS | 1 |
| Garbers, DL; Kopf, GS; Tubb, DJ | 2 |
| Hsu, SY; McIsaac, RJ | 1 |
| Amato, RS; Leuschen, MP | 1 |
| Boyse, EA; Goldstein, G; Scheid, MP | 1 |
| Briggs, WA | 1 |
| Francini, G; Galli, M; Gennari, C; Lore, F | 1 |
| Champion, S; Jacquemin, C | 1 |
| McAfee, DA; Siegel, B; Whiting, GJ | 1 |
| McClellan, GB; Winegrad, S | 1 |
| Schumm, DE; Webb, TE | 1 |
| Bachman, S; Levine, RA; Schwartzel, EH; Talev, JN | 1 |
| Kopeć, P; Tuganowski, W | 1 |
| Chronister, RB; Defrance, JF; Marchand, JE; Stanley, JC | 1 |
| Chavin, W; Honn, KV | 1 |
| Nakai, R; Okano, K; Tomori, T; Yoshikawa, M | 1 |
| Cooper, DM; Gleed, C | 1 |
| Dobson, WJ; Ho, J; McCurdy, HD | 1 |
| Champion, S; Jacquemin, C; Piot, JM | 1 |
| Nishio, H; Segawa, T; Takagi, H | 1 |
| Bransome, ED; Carrier, GO; Kolbeck, RC; Speir, WA | 1 |
| Hays, EF; Ramsey, R | 1 |
| Cohen, H; Iancu, L; Shneur, A | 1 |
| Stefanovich, V | 2 |
| Felt, BT; Hager, PJ; Schneider, DR; Schoener, EP | 1 |
| Canfield, SP; Curwain, BP; Price, C | 1 |
| Brodin, K; Fredholm, BB; Strandberg, K | 1 |
| Endoh, M | 2 |
| Asakura, K; Kataura, A | 1 |
| Black, AC; Sandquist, D; Wamsley, JK; West, JR; Williams, TH | 1 |
| Chang, MM; Ferrendelli, JA; Kinscherf, DA; Morgan, JF | 1 |
| de Jonge, HR | 1 |
| Leichtling, BH; Roper, MD; Wagner, K; Wicks, WD; Wimalasena, J | 1 |
| Bhargava, HN; Ho, LK; Loh, HH; Way, EL | 1 |
| Kumar, S; Prasad, KN | 1 |
| Bai, L; Miyazaki, M; Namba, M; Wahid, S | 1 |
| Gauthier, C; Le Bec, A; Lugnier, C; Soustre, H | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| Angielski, S; Kuchta, G; Redlak, M; Szczepańska-Konkel, M | 2 |
| Fukuda, A; Minami, T; Nabekura, J; Oomura, Y | 1 |
| Moreno, S; Tomes, C | 1 |
| Audsley, N; Phillips, JE | 1 |
| Barrett, KE; Cohn, JA; Dharmsathaphorn, K; Huott, PA; Wasserman, SI | 1 |
| Munkres, KD | 2 |
| Brückner, R; Gramann, S; Nose, M; Schmitz, W; Scholz, H | 1 |
| Gemba, M; Mikuriya, N; Nakajima, M; Nakanishi, J | 1 |
| Morton, DB; Truman, JW | 1 |
| Adachi, S; Nagahama, Y; Tan, JD | 1 |
| Cassity, N; Martinez, JR | 1 |
| Manganiello, VC; Osborne, JC; Wada, H | 1 |
| Dage, RC; Hsieh, CP; Kariya, T; Ruberg, SJ | 1 |
| Segal, J | 1 |
| Berson, EL; Crane, WG; Pawlyk, BS; Sandberg, MA; Schmidt, SY | 1 |
| Berkowitz, AS; Preslock, JP; Wun, WS | 1 |
| Eckstein, H | 1 |
| Böhm, M; Brückner, R; Neumann, J; Nose, M; Schmitz, W; Scholz, H | 1 |
| Aghajanian, GK; Wang, YY | 1 |
| Berry, L; Brigham, KL; Graber, S; Hussein, A; Meyrick, B | 1 |
| Stieve, H | 1 |
| Kotecha, N; Neild, TO | 1 |
| Rodger, IW; Shahid, M | 1 |
| Brazdil, R; Diocee, BK; Jordan, R; Souness, JE | 1 |
| Houslay, MD; Lakey, T; Lavan, BE | 1 |
| Jope, RS; Ormandy, GC | 1 |
| Boss, GR | 1 |
| Chang, YF; Chiang, BN; Lin, CI; Tao, PL | 1 |
| Chiou, WF; Wu, CC; Yen, MH | 1 |
| De Mello, WC; van Loon, P | 1 |
| Hoshi, T; Shimada, T | 1 |
| Maley, BE; Rush, ME; Simpson, WG; Vernon, MW | 1 |
| McCaldin, B; Tenang, EM | 1 |
| Kusel, M; Lucas, ML; McEwan, GT; McKie, AT | 1 |
| Kurtz, A | 1 |
| Burgess, MN; Daniel, H; Fett, C; Lucas, ML; McEwan, GT | 1 |
| Kagamimori, S; Kakiuchi, H; Naruse, Y; Shimizu, T; Williams, WR | 1 |
| Schneider, T; Zrenner, E | 1 |
| Green, K; Mayberry, L | 1 |
| Das, C; Gilliam, EB; Green, CG; Langone, JJ; McClure, JE; Shearer, WT; Ulrich, RG | 1 |
| de Jonge, HR; van Dommelen, FS | 1 |
| Christophe, J; De Neef, P; Deschodt-Lanckman, M; Robberecht, P | 1 |
| Jones, RE; Moscona, AA; Moscona, M | 1 |
| Handler, JS; Orloff, J; Sugita, M; Urakabe, S | 1 |
| Ignarro, LJ | 1 |
| George, WJ; Ignarro, LJ | 1 |
| Manganiello, VC; Stoner, JS; Vaughan, M | 1 |
| Higgins, WJ | 1 |
| Bosch, AL; Clark, MG; Kneer, NM; Lardy, HA | 1 |
| Murad, F | 1 |
| Dukor, P; Weissmann, G; Zurier, RB | 1 |
| Beavo, JA; Hardman, JG; Sutherland, EW | 1 |
| Goldberg, ND; Hedtke, J; Lust, WD; Polson, JB; Schafer, DE; Sircar, B; Thakur, AK | 1 |
| Goldberg, ND; Lust, WD; O'Dea, RF; O'Toole, AG; Wei, S | 1 |
| Maganiello, V; Vaughan, M | 1 |
| Fleischman, DE; Pannbacker, RG; Reed, DW | 1 |
| Delcher, HK; Lebovitz, HE; Rendall, JL | 1 |
| Solomon, SS | 1 |
| Goodman, AD; Pagliara, AS; Steiner, AL | 1 |
| Adlercreutz, P; Hirschowitz, BI; Jenkins, BC; Sachs, G; Sung, CP; Wiebelhaus, VD | 1 |
| Cooper, RH; McPherson, M; Schofield, JG | 1 |
| Dietmann, K; Juhran, W; Roesch, E; Schaumann, W | 1 |
| Chasin, M; Harris, DN; Hess, SM; Phillips, MB | 1 |
| Greengard, P; McAfee, DA | 1 |
| Hrapchak, RJ; Rasmussen, H | 1 |
| Suzuki, I; Wold, WS | 2 |
| Mazzocchi, G; Nussdorfer, GC | 1 |
| Gimpel, LP; Kostyo, JL; Rillema, JA | 1 |
| Kram, R; Tomkins, GM | 1 |
| Cehovic, G; Charollais, E; Posternak, T | 1 |
| Chang, MM; Ferrendelli, JA; Kinscherf, DA | 2 |
| Sheppard, H; Tsien, WH; Wiggan, G | 1 |
| Hovi, T; Vaheri, A | 1 |
| Alpers, DH; Ferrendelli, JA; Kinzie, JL | 1 |
| Gallin, J; Goldstein, I; Hoffstein, S; Weissmann, G | 1 |
| Fink, G; Gutman, RA; Penhos, JC; Recant, L; Selawry, H; Voyles, N | 1 |
| Castor, CW | 1 |
| Cohn, M; Epstein, R; Watson, J | 1 |
| Amer, MS | 1 |
| March, RB; Rojakovick, AS | 1 |
| Manganiello, VC; Stoner, J; Vaughan, M | 1 |
| Fredholm, BB | 1 |
| Hoffstein, S; Weissmann, G; Zurier, RB | 1 |
| Ciosek, CP; Newcombe, DS; Thanassi, NM | 1 |
| Baker, JC; Fuller, RW; Snoddy, HD | 1 |
| Bevers, MM; Smits, RA; van Rijn, J; van Wijk, R | 1 |
| Schroeder, J | 1 |
| Kimura, H; Murad, F | 1 |
| Barnabei, O; Luly, P; Tomasi, V; Trevisani, A; Tria, E | 1 |
| Amrhein, N; Fischer, U | 1 |
| Gee, JB; Khandwala, AS | 1 |
| Barnes, FS; Gamow, E | 1 |
| Wolberg, WH | 1 |
| Hidaka, H; Shibuya, M | 1 |
| Diamond, J; Hartle, DK | 1 |
| Parker, CW; Sullivan, TJ; Wedner, HJ | 1 |
| Dalton, C; Hope, H; Sheppard, H | 1 |
| Bensinger, R; Chader, G; Fletcher, R; Johnson, M | 1 |
| Chambaut, AM; Herman, G; Keryer, G; Rossignol, B | 1 |
| Curtis, D; Hogan, B; Shields, R | 1 |
| Pollock, K; Shields, R | 1 |
| Vapaatalo, H | 1 |
| Lackie, JM | 1 |
| Pazdernik, TL; Uyeki, EM | 1 |
| Abramowitz, J; Chavin, W | 1 |
| Gillette, RW; McKenzie, GO; Swanson, MH | 1 |
| Klotz, U; Vapaatalo, H | 1 |
| Delerue-Le Belle, N; Fontaine, YA; Fontaine-Bertrand, E | 1 |
| Hammond, MD; Schneider, C | 1 |
| Lehotay, DC; Murphy, BE | 1 |
| Manheimer, S; Pick, E | 1 |
| Mannigel, H; Schulz, I | 1 |
| Agrawal, R; Cowden, R; Fallon, EF; Furth, E; Steiner, AL | 1 |
| Fasano, A; Ferola, A; Guandalini, S; Marchesano, G; Migliavacca, M; Rao, MC; Rubino, A | 1 |
| Antonelli, T; Bianchi, C; Caciagli, F; Lambertini, L; Veratti, E | 1 |
| Ashton, JP; Murad, F; Pearl, RG; Rosenthal, MH | 1 |
| Catena, FB; Lombardi, L; Maiolo, AT; Peracchi, M; Polli, EE | 1 |
| Stellwagen, RH; Strindent, ST | 1 |
| Andersen, O; Eriksen, PB; Fenger, M; Knudsen, PJ; Nielsen, MK | 1 |
| Stellwagen, RH; Strinden, ST | 2 |
| Brown, BS; Krzanowski, JJ; Polson, JB; Wiggins, JR | 1 |
| Andersson, RG; Börjesson, S; Nilsson, KB | 1 |
| Epstein, PM; Hersh, EM; Ross, CP; Strada, SJ; Thompson, WJ | 1 |
| Boutwell, RK; Perchellet, JP | 3 |
| Betteridge, A | 1 |
| Oleshansky, MA | 1 |
| Kramer, GL; Wells, JN | 1 |
| Frossard, N; Landry, Y; Pauli, G; Ruckstuhl, M | 1 |
| Fredholm, B; Sydbom, A; Uvnäs, B | 1 |
| Daoud, MS; Davison, JS; Pearson, GT; Petersen, OH; Singh, J | 1 |
| Boeynaems, JM; Dumont, JE; Erneux, C; Miot, F | 1 |
| Fredholm, BB; Sydbom, A | 1 |
| Amakawa, T; Hayashi, F; Inoue, H; Takagi, M; Yoshioka, T | 1 |
| Bartfai, T; Lazaridis, G; Tjörnhammar, ML | 1 |
| Kopf, GS; Lewis, CA; Vacquier, VD | 1 |
| Daniel, JW; Oleinick, NL | 1 |
| Wainwright, LK; Wainwright, SD | 2 |
| Dobbins, JW; Forrest, JN; Laurenson, JP | 1 |
| Grotendorst, GR; Schimmel, SD | 1 |
| Carpenter, CB; Strom, TB | 1 |
| Wainwright, SD | 1 |
| Bourdeaux, AM; Giudicelli, Y; Nordmann, J; Nordmann, R; Rebourcet, MC | 1 |
| Fox, A; Reinhardt, D; Schuhmacher, P; Stemmann, EA; Wegner, F | 1 |
| Argel, MI; Chiappe, GE; Chiappe, LE; Cingolani, HE; Grassi, AO; Vittone, L | 1 |
| Fang, VS; Furuhashi, N | 1 |
| Bourguignon, LY; Butman, BT; Cabatu, OG; Jacobsen, T | 1 |
| Kiefer, KA; Malarkey, WB; Matthews, RH | 1 |
| Della Torre, G; Dolcini, BM; Fanò, G; Orlacchio, A; Principato, GB | 1 |
| Kitamura, A; Miyake, Y; Okamoto, S; Shimoyama, M; Tanigawa, Y | 1 |
| Kovár, J | 1 |
| Berridge, MJ; Heslop, JP | 1 |
| Clemente, F; Estival, A; Ribet, A | 1 |
| Argenzio, RA; Whipp, SC | 1 |
| Flitney, FW; Singh, J | 1 |
| Kononenko, NI | 1 |
| Kishi, Y; Numano, F | 1 |
| Harty, RF; McGuigan, JE | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Caciagli, F; Lambertini, L; Veratti, E | 1 |
| Berti, C; Lalumera, M; Marcolongo, R; Morozzi, G; Pellegrini, R | 1 |
| de Harven, E; Liepins, A | 1 |
| Masada, M; Negishi, S; Obika, M; Ohoka, T; Wakamatsu, Y | 1 |
| Ahrens, J | 1 |
| Einstein, R; Levin, RM; Wein, AJ | 1 |
| Breuiller, M; Cedard, L; Ferre, F | 1 |
| Esakov, AI; Meshcheriakova, OD | 1 |
| De Mello, WC; Estapé-Wainwright, E | 1 |
| Abboud, HE; Dousa, TP | 1 |
| Saito, Y; Wright, EM | 1 |
| Argenzio, RA; Schmall, LM; Whipp, SC | 1 |
| Field, M; Nash, NT; Rao, MC | 1 |
| Schmidt, RR; Shipman, PM | 1 |
| Bereta, J; Bereta, M; Coffman, FD; Cohen, MC; Cohen, S; Georgoff, I | 1 |
| Usachev, Y; Verkhratsky, A | 1 |
| Banner, KH; Page, CP | 1 |
| Anfossi, G; Cavalot, F; Hahn, A; Massucco, P; Mattiello, L; Mularoni, E; Trovati, M | 1 |
| Ballou, LM; Edelmann, HM; Petritsch, C; Woscholski, R | 1 |
| Dent, G; Magnussen, H; Rabe, KF | 1 |
| Buanes, T; Christensen, G; Grotmol, T; Landsverk, T; Rødnes, JT | 1 |
| Spessert, R; Vollrath, L | 1 |
| Barnes, PJ | 1 |
| Copello, J; Heming, TA; Reuss, L | 1 |
| Field, M; Minhas, BS; Sullivan, SK | 1 |
| Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC | 1 |
| Denaro, MG; Faggio, C; Mandolfino, M; Schettino, T; Trischitta, F | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Paoletti, G; Piretto, V; Trovati, M | 1 |
| Camello, PJ; Petersen, OH; Toescu, EC | 1 |
| McCulloch, AI; Randall, MD | 1 |
| Armstead, WM | 1 |
| García de Boto, MJ; Hidalgo, A; Menéndez, L; Sánchez, M | 1 |
| Chlopicki, S; Gryglewski, RJ; Jakubowski, A; Lomnicka, M; Niezabitowski, P | 1 |
| Haskó, G; Németh, ZH; Szabó, C; Vizi, ES | 1 |
| Cornwell, TL; Cundiff, DL; Gately, S; Lincoln, TM; Soff, GA | 1 |
| Kuriu, T; Nakaoka, Y; Oosawa, Y; Watanabe, Y | 1 |
| Kildalsen, H; Sager, G; Schultz, C; Vaskinn, S | 1 |
| Fukuoka, M; Kubo, H; Nakahara, H; Nakajima, S; Ohkawa, K; Tohda, Y | 1 |
| Dasso, M; Rosenzweig, S; Spielman, AI; Yan, W | 1 |
| Christophersen, P; Jensen, BS; Olesen, SP; Schrøder, RL; Strøbaek, D | 1 |
| Baba, A; Enomoto, R; Lee, E; Matsuda, T; Mori, K; Takuma, K | 1 |
| Harayama, H; Kato, S | 1 |
| Fang, H; Liu, J; Ni, W; Xu, Y; Zhang, N; Zhang, Z | 1 |
| Baskakov, MB; D'yakova, EY; Kapilevich, LV; Kovalev, IV; Nosarev, AV | 1 |
| Abdollahi, M; Bahreini-Moghadam, A; Emami, B; Fooladian, F; Zafari, K | 1 |
| Butt, SJ; Pitman, RM | 1 |
| Drummond, CA; Fioravanti, CF; Smith, SL; Vandock, KP | 1 |
| Henkin, RI; Schmidt, L; Velicu, I | 1 |
| Aronsen, L; Lysaa, R; Orvoll, E; Ravna, AW; Sager, G | 1 |
| Chlebek, JL; Dalia, AB; Dalia, TN | 1 |
| Ahn, SH; Bae, SI; Chung, S; Hwang, Y; Lee, S; Ok, SH; Park, KE; Sim, G; Sohn, JT | 1 |
15 review(s) available for theophylline and cyclic gmp
| Article | Year |
|---|---|
A role for cyclic nucleotides and protein kinase in vertebrate photoreception.
Topics: Animals; Anura; Cattle; Cyclic AMP; Cyclic GMP; Darkness; Guanylate Cyclase; Kinetics; Light; Papaverine; Photoreceptor Cells; Protein Kinases; Retina; Rhodopsin; Species Specificity; Subcellular Fractions; Theophylline | 1976 |
Pharmacologic modulation of inflammatory mediator release by rat mast cells.
Topics: Animals; Antibodies; Calcimycin; Calcium; Catecholamines; Cell Membrane; Concanavalin A; Cyclic AMP; Cyclic GMP; Histamine Release; Humans; Immunoglobulin E; Inflammation; Kinetics; Mast Cells; p-Methoxy-N-methylphenethylamine; Prostaglandins E; Rats; Theophylline | 1976 |
The role of renal adenosine 3',5'-monophosphate in the control of erythropoietin production.
Topics: Adenine Nucleotides; Adenylyl Cyclases; Animals; Bucladesine; Cobalt; Cyclic AMP; Cyclic GMP; Enzyme Activation; Erythropoietin; Humans; Hypoxia; Kidney; Kidney Cortex; Mice; Phosphoric Diester Hydrolases; Prostaglandins; Protein Kinases; Rats; Stimulation, Chemical; Theophylline | 1975 |
Hormone receptors - their function in cell membranes and some problems related to methodology.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Bacitracin; Binding Sites; Carbachol; Cell Membrane; Cells, Cultured; Cyclic GMP; Enzyme Activation; Fibroblasts; Glucagon; Growth Hormone; Insulin; Kinetics; Lipid Mobilization; Liver; Lymphocytes; Methods; Receptors, Cell Surface; Theophylline; Thymidine | 1975 |
[Present status and prospects of platelet inhibitors].
Topics: Adenosine; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Combinations; Drug Synergism; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Prostaglandins E; Serotonin; Theophylline; Thrombosis | 1976 |
The role of cyclic nucleotides in the cell cycle.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Cyclic GMP; DNA Replication; Fibroblasts; Genetic Variation; HeLa Cells; Kinetics; Liver; Lymphocytes; Mice; Mitosis; Skin; Theophylline; Thymidine; Time Factors | 1976 |
Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues.
Topics: Adipose Tissue; Animals; Arteries; Benzyl Compounds; Caudate Nucleus; Cerebral Cortex; Cyclic GMP; Dogs; Dopamine; Erythrocytes; Ethers; Imidazoles; Mesenteric Arteries; Methyl Ethers; Muscle, Smooth; Myocardium; Norepinephrine; Organ Specificity; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Structure-Activity Relationship; Theophylline; Tyramine; Veins | 1972 |
Cyclic GMP and gastric acid secretion.
Topics: Animals; Cyclic AMP; Cyclic GMP; Depression, Chemical; Gallbladder; Gastric Juice; Glycyrrhiza; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Plants, Medicinal; Stimulation, Chemical; Theophylline; Triterpenes | 1974 |
Cyclic AMP and the immune response;.
Topics: Adrenocorticotropic Hormone; Animals; B-Lymphocytes; Bucladesine; Cell Transformation, Neoplastic; Concanavalin A; Cyclic AMP; Cyclic GMP; Humans; Immunity; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Models, Biological; Phagocytosis; Subcellular Fractions; T-Lymphocytes; Theophylline | 1974 |
Role of cyclic nucleotides in the nervous system.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Cyclic GMP; Diaphragm; Humans; Muscle Contraction; Myasthenia Gravis; Papaverine; Rats; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Tubocurarine | 1974 |
Phosphodiesterase inhibitors as tools in cyclic nucleotide research: a precautionary comment.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Cyclic AMP; Cyclic GMP; Isoenzymes; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1981 |
Cyclic nucleotides in immunosuppression--neuroendocrine pharmacologic manipulation and in vivo immunoregulation of immunity acting via second messenger systems.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Immune Tolerance; Immunity, Cellular; Isoproterenol; Lymphocyte Activation; Mice; Rats; Receptors, Cell Surface; T-Lymphocytes; Theophylline | 1980 |
Immunomodulatory actions of xanthines and isoenzyme selective phosphodiesterase inhibitors.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Humans; Isoenzymes; Muscle, Smooth; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1995 |
Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants.
Topics: Animals; Bronchi; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Humans; Muscle, Smooth; Muscle, Smooth, Vascular; Parasympatholytics; Phosphodiesterase Inhibitors; Pulmonary Artery; Theophylline | 1995 |
Cyclic nucleotides and phosphodiesterases and airway function.
Topics: Animals; Asthma; Cyclic AMP; Cyclic GMP; Humans; Isoenzymes; Muscle, Smooth; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Respiratory Physiological Phenomena; Respiratory System; Theophylline | 1995 |
1 trial(s) available for theophylline and cyclic gmp
| Article | Year |
|---|---|
Effects of theophylline on plasma levels of interleukin-4, cyclic nucleotides and pulmonary functions in patients with chronic obstructive pulmonary disease.
Topics: Aged; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Interleukin-4; Male; Maximal Expiratory Flow Rate; Middle Aged; Pulmonary Disease, Chronic Obstructive; Theophylline | 1999 |
357 other study(ies) available for theophylline and cyclic gmp
| Article | Year |
|---|---|
Cylic nucleotide phosphodiesterase in silkworm. Characterization of cyclic GMP phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Bombyx; Caffeine; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Cyclic IMP; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Molecular Weight; Nucleotides; Phosphoric Diester Hydrolases; Theophylline | 1975 |
Biochemical properties of cyclic nucleotide phosphodiesterase in metastasizing and nonmetastasizing rat mammary carcinomas.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Calcium; Cobalt; Cyclic AMP; Cyclic GMP; Depression, Chemical; Edetic Acid; Egtazic Acid; Hydrogen-Ion Concentration; Magnesium; Manganese; Neoplasm Metastasis; Nickel; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Theophylline; Zinc | 1976 |
Effects of egg factors on cyclic nucleotide metabolism in sea urchin sperm.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Aggregation; Cyclic AMP; Cyclic GMP; Egg Proteins; Female; Guanylate Cyclase; Kinetics; Male; Ovum; Sea Urchins; Seawater; Sperm-Ovum Interactions; Spermatozoa; Theophylline; Xanthines | 1976 |
Cyclic nucleotides and crustacean blood glucose levels.
Topics: Adenine; Adenosine Monophosphate; Animals; Astacoidea; Blood Glucose; Brachyura; Cyclic AMP; Cyclic GMP; Fluorides; Hemolymph; Kinetics; Male; Species Specificity; Theophylline | 1976 |
Involvement of cyclic nucleotides in the beating response of rat heart cells in culture.
Topics: Acetylcholine; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Glucagon; Hydrocortisone; Isoproterenol; Myocardial Contraction; Myocardium; Rats; Theophylline | 1976 |
Cyclic nucleotide phosphodiesterases of Hyalophora cecropia silkmoth fat body.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Bombyx; Caffeine; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Edetic Acid; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Larva; Manganese; Phosphoric Diester Hydrolases; Theophylline | 1977 |
Effect of concanavalin A on tyrosine aminotransferase in rat hepatoma tissue culture cells. Rapid reversible inactivation of soluble enzyme.
Topics: Alanine Transaminase; Animals; Carcinoma, Hepatocellular; Cell Line; Concanavalin A; Cyclic AMP; Cyclic GMP; Enzyme Induction; Fluorouracil; Kinetics; L-Lactate Dehydrogenase; Liver Neoplasms; Rats; Theophylline; Tyrosine Transaminase | 1977 |
A serotonin sensitive guanylate cyclase associated with specific neurotransmitter binding sites on isolated synaptic membranes from mature rat brain.
Topics: Animals; Binding Sites; Brain; Cyclic GMP; Guanylate Cyclase; In Vitro Techniques; Male; Neurotransmitter Agents; Rats; Serotonin; Synaptic Membranes; Theophylline | 1978 |
Adrenergic- and cyclic nucleotide-induced glycerol release from brown adipocytes.
Topics: Adenosine Monophosphate; Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Cricetinae; Cyclic AMP; Cyclic GMP; Glycerol; Isoproterenol; Male; Mesocricetus; Phenylephrine; Theophylline | 1979 |
Cyclic nucleotide phosphodiesterase activity of human normal and carcinomatous lung tissue.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Caffeine; Carcinoma, Squamous Cell; Cyclic AMP; Cyclic GMP; Female; Humans; Lung; Lung Neoplasms; Middle Aged; Phosphoric Diester Hydrolases; Theophylline | 1976 |
Cholinergic stimulation of skeletal muscle alanine and glutamine formation and release. Evidence for mediation by a nicotinic cholinergic receptor and guanosine 3':5'-monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; Alanine; Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Glutamine; Hexamethonium Compounds; Muscles; Phosphorylases; Pilocarpine; Quaternary Ammonium Compounds; Rats; Receptors, Cholinergic; Receptors, Nicotinic; Theophylline | 1978 |
Effect of a phosphodiesterase inhibitor on cyclic GMP changes induced by muscarinic agonists in mouse neuroblastoma cells [proceedings].
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic GMP; Mice; Neuroblastoma; Parasympathomimetics; Theophylline | 1978 |
Effects of phosphodiesterase inhibitors, imidazole and phosphate on cyclic CMP phosphodiesterase are different from those on cyclic AMP and cyclic GMP phosphodiesterases.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic AMP; Cyclic GMP; Imidazoles; Liver; Male; Myocardium; Organ Specificity; Papaverine; Phosphates; Phosphodiesterase Inhibitors; Rats; Theophylline | 1978 |
A possible role for cyclic GMP in mediating the effect of luteinizing hormone releasing hormone on gonadotropin release in dispersed pituitary cells of the female rat.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Theophylline | 1978 |
Methacholine-induced attenuation of methylisobutylxanthine- and isoproterenol-elevated cyclic AMP levels in isolated rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Methacholine Compounds; Myocardium; Rats; Theophylline | 1979 |
Molecular control of rabbit follicular testosterone production: role of cyclic AMP and cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Female; Ovary; Protein Biosynthesis; Puromycin; Rabbits; RNA; Testosterone; Theophylline | 1979 |
Neutrophil chemotaxis in psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Child; Cyclic AMP; Cyclic GMP; Epidermis; Ethylenediamines; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Neutrophils; Phosphodiesterase Inhibitors; Psoriasis; Skin; Theophylline | 1979 |
Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro.
Topics: Amylases; Animals; Bucladesine; Caffeine; Calcimycin; Calcium; Cholecystokinin; Cholera Toxin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Pancreas; Rats; Secretory Rate; Theophylline | 1979 |
Subcellular distribution of the enzymes related to the cellular action of vasopressin in renal medulla.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Fractionation; Cell Membrane; Cyclic AMP; Cyclic GMP; Cytosol; Fluorides; Histones; Kidney; Kidney Medulla; Kinetics; L-Lactate Dehydrogenase; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Protein Kinases; Proteins; Subcellular Fractions; Theophylline; Vasopressins | 1975 |
The influence of cyclic nucleotides (c-AMP and c-GMP) on the nitrous blue tetrazolium reduction by human polymorphonuclear leucocytes.
Topics: Ascorbic Acid; Coloring Agents; Cyclic AMP; Cyclic GMP; Drug Antagonism; Endotoxins; Humans; Leukocytes; Methylene Blue; Oxidation-Reduction; Phagocytosis; Tetrazolium Salts; Theophylline | 1975 |
The modulation of spontaneous and anti-Ig-stimulated motility of lymphocytes by cyclic nucleotides and adrenergic and cholinergic agents.
Topics: Acetylcholine; Animals; Antibodies, Anti-Idiotypic; Antigen-Antibody Complex; Atropine; B-Lymphocytes; Binding Sites; Carbachol; Cell Membrane; Cell Movement; Colchicine; Cyclic AMP; Cyclic GMP; Endocytosis; Immunoglobulins; Isoproterenol; Mice; Nucleotides, Cyclic; Parasympathomimetics; Phenylephrine; Sympathomimetics; Theophylline | 1975 |
Light-stimulated phosphorylation of rhodopsin in the retina: the presence of a protein kinase that is specific for photobleached rhodopsin.
Topics: Adenosine Triphosphate; Animals; Caseins; Cattle; Cyclic AMP; Cyclic GMP; Enzyme Activation; Histones; Light; Phosphates; Phosphodiesterase Inhibitors; Phosphorus Radioisotopes; Photic Stimulation; Photoreceptor Cells; Protein Kinases; Retinal Pigments; Rhodopsin; Theophylline | 1975 |
Cyclic 3',5'-AMP phosphodiesterase of rabbit aorta.
Topics: Animals; Aorta; Brain; Calcium; Cyclic AMP; Cyclic GMP; Enzyme Activation; Kinetics; Magnesium; Muscle, Smooth; Papaverine; Phosphoric Diester Hydrolases; Rabbits; Theophylline | 1975 |
Cyclic nucleotide phosphodiesterases and thyroid hormones.
Topics: Adipose Tissue; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Epinephrine; Glycerol; Hypothyroidism; Kinetics; Lipid Mobilization; Male; Phosphoric Diester Hydrolases; Propylthiouracil; Protein Kinases; Rats; Theophylline; Thyroid Gland; Thyroid Hormones; Time Factors; Triiodothyronine; Xanthines | 1975 |
Acetylcholine-induced initiation of thymic lymphoblast DNA synthesis and proliferation.
Topics: Acetylcholine; Animals; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; DNA; Male; Radioimmunoassay; Rats; T-Lymphocytes; Theophylline | 1975 |
Cyclic adenosine 3':5'-monophosphate and the induction of deoxyribonucleic acid synthesis in liver.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Bucladesine; Butyrates; Cyclic AMP; Cyclic GMP; DNA Replication; Enzyme Activation; Female; Glucagon; Liver; Ornithine Decarboxylase; Rats; Theophylline; Triiodothyronine | 1975 |
Nucleolar changes in liver before the onset of deoxyribonucleic acid replication.
Topics: Amino Acids; Animals; Bucladesine; Cell Nucleolus; Cyclic GMP; DNA; DNA Replication; DNA-Directed RNA Polymerases; Heparin; Kinetics; Liver; Rats; Sodium Chloride; Theophylline; Time Factors; Triiodothyronine | 1975 |
The role of calcium and cyclic nucleotides in alpha-amylase release from slices of rat parotid: studies with the divalent cation ionophore A-23187.
Topics: Amylases; Animals; Atropine; Biological Transport; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Isoproterenol; Parotid Gland; Phentolamine; Potassium; Propranolol; Rats; Stimulation, Chemical; Theophylline; Time Factors | 1975 |
Imbalanced cyclic AMP-cyclic GMP levels in psoriasis.
Topics: Animals; Bucladesine; Cell Differentiation; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; DNA; Glycogen; Humans; Mice; Papaverine; Psoriasis; Skin; Theophylline; Xanthines | 1975 |
Regulation of theta-antigen expression by agents altering cyclic AMP level and by thymic factor.
Topics: Acetylcholine; Adenosine; Animals; Antilymphocyte Serum; Azathioprine; Bucladesine; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Immune Adherence Reaction; Isoantigens; Lymphocytes; Mice; Mice, Inbred AKR; Mice, Nude; Prostaglandins; Radiation Chimera; Spleen; Theophylline; Thymectomy; Thymosin; Thymus Extracts | 1975 |
The effects of cyclic adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate and theophylline on renin secretion in the isolated perfused kidney of the rat.
Topics: Animals; Biological Assay; Cyclic AMP; Cyclic GMP; Juxtaglomerular Apparatus; Kidney; Propranolol; Rats; Renin; Theophylline | 1975 |
Effects of pharmacologic agents on release of lysosomal enzymes from alveolar mononuclear cells.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Bucladesine; Colchicine; Cyclic AMP; Cyclic GMP; Cytochalasin B; Dimethyl Sulfoxide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Leukocytes; Lysosomes; Macrophages; Microtubules; Prostaglandins E; Prostaglandins F; Pulmonary Alveoli; Theophylline | 1975 |
Differences and similarities between guanosine 3',5'-cyclic monophosphate phosphodiesterase and adenosine 3',5'-cyclic monophosphate phosphodiesterase activities in neuroblastoma cells in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Buffers; Cell Fractionation; Cells, Cultured; Clone Cells; Cyclic GMP; Deoxyribonucleases; Humans; Mice; Neuroblastoma; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Proteins; Ribonucleases; Theophylline | 1975 |
Generation of superoxide anions by leukocytes treated with cytochalasin E.
Topics: Animals; Bucladesine; Cyanides; Cyclic AMP; Cyclic GMP; Cytochalasins; Cytochrome c Group; Deoxyglucose; Ethylmaleimide; Guinea Pigs; Iodoacetates; Leukocytes; Manganese; Nitroblue Tetrazolium; Oxygen; Superoxide Dismutase; Superoxides; Theophylline | 1975 |
Morphological differentiation of cultured mouse glioblastoma cells induced by dibutyryl cyclic adenosine monophosphate.
Topics: Animals; Bucladesine; Butyrates; Cell Differentiation; Cell Line; Cells, Cultured; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Mice; Neoplasms, Experimental; Neuroglia; Theophylline; Thymidine; Time Factors | 1975 |
Effect of cyclic nucleotides on the cyanide-insensitive respiration of polymorphonuclear leucocytes.
Topics: Animals; Bucladesine; Cyanides; Cyclic AMP; Cyclic GMP; Escherichia coli; Guinea Pigs; In Vitro Techniques; Leukocytes; Methylene Blue; Microsomes, Liver; Myristic Acids; Nucleotides, Cyclic; Oxygen Consumption; Phagocytosis; Rats; Theophylline; Trypsin | 1975 |
The action of neurotransmitter hormones and analogues and cyclic nucleotides and theophylline on electrolyte transport by the excretory duct of the rabbit mandibular gland.
Topics: Acetylcholine; Animals; Atropine; Biological Transport; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Electrolytes; Female; Isoproterenol; Male; Norepinephrine; Rabbits; Salivary Glands; Theophylline | 1975 |
Effect of lithium ions on RNA synthesis in mammary gland explants of mice.
Topics: Animals; Culture Techniques; Cyclic GMP; Female; Hydrocortisone; Insulin; Ions; Lithium; Mammary Glands, Animal; Mice; Pregnancy; Prolactin; Quinine; RNA; Theophylline; Tritium; Uridine | 1975 |
Cyclic AMP and cyclic GMP: mediators of the mechanical effects on bone remodeling.
Topics: Animals; Bone and Bones; Bone Development; Chick Embryo; Cyclic AMP; Cyclic GMP; Epiphyses; Hydrostatic Pressure; Stress, Mechanical; Theophylline; Tibia | 1975 |
The effect of agents which modulate levels of the cyclic nucleotides on human lymphotoxin secretion and activity in vitro.
Topics: Bucladesine; Carbachol; Concanavalin A; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Humans; Imidazoles; Isoproterenol; Lymphocytes; Lymphotoxin-alpha; Theophylline | 1975 |
Yin/Yang modulation of lysosomal enzyme release from polymorphonuclear leukocytes by cyclic nucleotides.
Topics: Animals; Ascitic Fluid; Cells, Cultured; Colchicine; Complement C5; Cyclic AMP; Cyclic GMP; Cytochalasin B; Glucuronidase; Guinea Pigs; Humans; Hydrolases; Lysosomes; Microtubules; Models, Biological; Neutrophils; Phagocytosis; Tetradecanoylphorbol Acetate; Theophylline; Zymosan | 1975 |
Regulation of aryl hydrocarbon (benzo-(A)-pyrene) hydroxylase activity in mammalian cells. Induction of hydroxylase activity by N6,O2'-dibutyryl8 adenosine 3':5'-monophosphate and aminophylline.
Topics: Aminophylline; Benzopyrene Hydroxylase; Bucladesine; Cell Line; Cyclic AMP; Cyclic GMP; Cycloheximide; Enzyme Induction; Kinetics; Mixed Function Oxygenases; Papaverine; Theophylline | 1975 |
Effects of arachidonic acid on RNA metabolism in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Breast; Bucladesine; Cyclic GMP; Female; Indomethacin; Linoleic Acids; Mice; Oleic Acids; Pregnancy; Prolactin; Prostaglandins E; Prostaglandins F; Quinine; RNA; Stearic Acids; Theophylline; Uridine | 1975 |
A cAMP receptor from mouse liver cytosol whose binding capacity is enhanced by Mg++-ATP.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Cyclic AMP; Cyclic GMP; Cytosol; Enzyme Activation; Kinetics; Liver; Magnesium; Mice; Protein Binding; Protein Kinases; Receptors, Drug; Theophylline | 1975 |
Cyclic GMP and lectin-induced lymphocyte activation.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Humans; Lectins; Leukocytes; Lymphocyte Activation; Radioimmunoassay; Theophylline | 1975 |
The role of extracellular Ca2+ and cyclic nucleotides in the mechanism of enzyme secretion from the cat pancreas.
Topics: Animals; Calcium; Cats; Cyclic AMP; Cyclic GMP; Drug Synergism; Enzyme Induction; Female; Male; Nucleotides, Cyclic; Pancreas; Proteins; Theophylline | 1975 |
Cyclic nucleotides and amphibian development.
Topics: Ambystoma; Amphibians; Animals; Anura; Bucladesine; Cell Division; Cyclic AMP; Cyclic GMP; Embryo, Nonmammalian; Embryonic Development; Female; Oocytes; Rana temporaria; Species Specificity; Theophylline; Xenopus | 1975 |
Calcium distribution in islets of Langerhans: a study of calcium concentrations and of calcium accumulation in B cell organelles.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Bucladesine; Caffeine; Calcium; Cell Nucleus; Cyclic AMP; Cyclic GMP; Cytoplasm; Cytoplasmic Granules; Endoplasmic Reticulum; Female; Islets of Langerhans; Mitochondria; Rats; Subcellular Fractions; Theophylline; Xanthines | 1975 |
The stimulation of the phospholipase A2-acylation system of synaptic membranes of brain by cyclic nucleotides.
Topics: Acylation; Adenosine; Animals; Brain; Calcium Chloride; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Magnesium; Norepinephrine; Nucleotides, Cyclic; Oleic Acids; Phosphatidylcholines; Phospholipases; Synaptic Membranes; Theophylline | 1975 |
Induction of thymidylate synthetase activity in Tetrahymena by cyclic guanosine monophosphate.
Topics: Animals; Bucladesine; Caffeine; Cell Division; Culture Media; Cyclic GMP; Enzyme Induction; Methyltransferases; Tetrahymena pyriformis; Theophylline; Thymidylate Synthase | 1975 |
Phosphodiesterases from porcine coronary arteries: inhibition of separated forms by xanthines, papaverine, and cyclic nucleotides.
Topics: Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Enzyme Activation; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Swine; Theophylline; Xanthines | 1975 |
Cellular cyclic nucleotides and enzyme secretion in the pancreatic acinar cell.
Topics: Animals; Atropine; Carbachol; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Ceruletide; Cholecystokinin; Cyclic AMP; Cyclic GMP; Drug Interactions; Guinea Pigs; Imidazoles; In Vitro Techniques; Oxidative Phosphorylation; Pancreas; Rabbits; Receptors, Cholinergic; Theophylline | 1976 |
The enhanced production of hyaluronic acid by cultured rat fibroblast cells treated with cyclic AMP and its dibutyryl derivative.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bromodeoxyuridine; Bucladesine; Butyrates; Cell Count; Cell Division; Cell Line; Chondroitin Sulfates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glucuronates; Glucuronosyltransferase; Glycosaminoglycans; Heparitin Sulfate; Hyaluronic Acid; Prostaglandins E; Stimulation, Chemical; Theophylline | 1975 |
The content and metabolism of cyclic adenosine 3', 5'-monophosphate and cyclic guanosine 3', 5'-monophosphate in adenocarcinoma of the human colon.
Topics: Adenocarcinoma; Adenylyl Cyclases; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Humans; Intestinal Mucosa; Prostaglandins E; Theophylline | 1976 |
The involvement of cyclic-3',5'-AMP in the release of hormones from the anterior pituitary in vitro.
Topics: Adenosine Monophosphate; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Enterotoxins; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Growth Hormone; Hypothalamus; In Vitro Techniques; Luteinizing Hormone; Male; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Potassium; Prolactin; Rats; Theophylline; Thyrotropin; Thyrotropin-Releasing Hormone | 1976 |
Cyclic AMP inhibits synthesis of prostaglandin endoperoxide (PGG2) in human platelets.
Topics: Arachidonic Acids; Blood Platelets; Bucladesine; Collagen; Cyclic AMP; Cyclic GMP; Humans; Indomethacin; Peroxides; Platelet Aggregation; Prostaglandins; Prostaglandins E; Serotonin; Theophylline | 1976 |
Ability of various factors to oppose the stimulatory effect of dibutyrylcyclic AMP on the release of melanocyte-stimulating hormone by the rat pituitary in vitro.
Topics: Animals; Bucladesine; Cyclic GMP; Dopamine; In Vitro Techniques; Male; Melanocyte-Stimulating Hormones; Ouabain; Oxytocin; Peptides; Pituitary Gland; Rats; Serotonin; Theophylline | 1976 |
Neuroblastoma cell adenylate cyclase: direct activation by adenosine and prostaglandins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenylyl Cyclases; Cell Line; Cyclic GMP; Dopamine; Isoproterenol; Kinetics; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Papaverine; Prostaglandins E; Prostaglandins F; Theophylline | 1976 |
Possible interaction of cyclic nucleotides with the prolactin stimulation of casein synthesis in mouse mammary gland explants.
Topics: Animals; Bucladesine; Caseins; Cells, Cultured; Cyclic GMP; Female; Leucine; Mammary Glands, Animal; Mice; Pregnancy; Prolactin; Protein Biosynthesis; Quinine; Theophylline; Time Factors | 1976 |
Phospholipases and the effect of prolactin on uridine incorporation into RNA in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Bucladesine; Cyclic GMP; Female; Indomethacin; Mammary Glands, Animal; Organ Culture Techniques; Phospholipases; Pregnancy; Prolactin; Prostaglandins E; Quinine; Rats; RNA; Theophylline; Transcription, Genetic; Uridine | 1976 |
Influence of cyclic nucleotides on protein synthesis in vascular smooth muscle.
Topics: Aminoisobutyric Acids; Animals; Cattle; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Leucine; Mesenteric Arteries; Muscle Proteins; Muscle, Smooth; Papaverine; Theophylline | 1976 |
Effects of cytochalasin B and dibutyryl cyclic AMP on intraleukocytic bactericidal activity.
Topics: Blood Bactericidal Activity; Bucladesine; Cyclic AMP; Cyclic GMP; Cytochalasin B; Glucosephosphate Dehydrogenase; Hexosephosphates; Humans; Leukocytes; NADH, NADPH Oxidoreductases; Nitroblue Tetrazolium; Pentosephosphates; Phagocytosis; Stimulation, Chemical; Theophylline | 1976 |
Effects of kainic acid, a cyclic analogue of glutamic acid, on cyclic nucleotide accumulation in slices of rat cerebellum.
Topics: Animals; Brain Stem; Calcium; Cerebellum; Cocaine; Cyclic AMP; Cyclic GMP; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Stimulation, Chemical; Structure-Activity Relationship; Theophylline; Time Factors | 1976 |
Cyclic nucleotides in spinal cells.
Topics: Action Potentials; Animals; Cats; Cyclic AMP; Cyclic GMP; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Spine; Theophylline; Time Factors | 1976 |
The effects of noradrenaline, acetylcholine, cyclic AMP, cyclic GMP, and other agents on the concentration of unesterified fatty acids in synaptosomes and synaptic membranes.
Topics: Acetylcholine; Animals; Calcium; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Fatty Acids, Nonesterified; Fluorides; Guinea Pigs; Norepinephrine; Potassium Chloride; Sodium Chloride; Synaptic Membranes; Synaptosomes; Theophylline | 1976 |
Biochemical aspects of cardiac muscle differentiation. Possible control of deoxyribonucleic acid synthesis and cell differentiation by adrenergic innervation and cyclic adenosine 3':5'-monophosphate.
Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic GMP; DNA Replication; Heart; Isoproterenol; Muscle Proteins; Muscle, Smooth; Myocardium; Myosins; Norepinephrine; Phenylephrine; Protein Biosynthesis; Rats; Theophylline | 1976 |
Calcium-dependent regulation of guanosine 3',5'-monophosphate in renal cortex: effects of ionophore A23187 and tetracaine and evidence for independent control of adenosine 3',5'-monophosphate.
Topics: Animals; Anti-Bacterial Agents; Atropine; Calcimycin; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Glucagon; In Vitro Techniques; Isoproterenol; Kidney Cortex; Kinetics; Magnesium; Male; Parathyroid Hormone; Rats; Tetracaine; Theophylline | 1976 |
Mechanism of inhibition of organic acid transport in rabbit renal cortex by cyclic AMP.
Topics: Adenine; Animals; Biological Transport, Active; Cyclic AMP; Cyclic GMP; Iodohippuric Acid; Isoproterenol; Kidney Cortex; Kinetics; Parathyroid Hormone; Propranolol; Rabbits; Theophylline; Uric Acid | 1976 |
Regulation of tubulin synthesis in islets of Langerhans.
Topics: Animals; Cyclic AMP; Cyclic GMP; Fasting; Glucose; Glycoproteins; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Protein Biosynthesis; Rats; Theophylline; Tubulin | 1976 |
Modulation of postjunctional cholinergic sensitivity of rat diaphragm muscle by cyclic adenosine monophosphate.
Topics: Acetylcholine; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Diaphragm; Membrane Potentials; Muscle, Smooth; Neuromuscular Junction; Rats; Theophylline | 1976 |
Partial purification of adenosine 3',5'-cyclic monophosphate phosphodiesterases from rat pancreas in the presence of excess protease inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Cyclic GMP; Cyclic IMP; Isoenzymes; Kinetics; Male; Pancreas; Phosphoric Diester Hydrolases; Protease Inhibitors; Rats; Theophylline | 1976 |
Regulation by glucose and cyclic nucleotides of the glucagon and insulin release induced by amino acids.
Topics: Acetylcholine; Alanine; Amino Acids; Animals; Arginine; Bucladesine; Cyclic GMP; Drug Synergism; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Rats; Sodium Chloride; Stimulation, Chemical; Theophylline | 1975 |
Inhibitory effects of dibutyryl cyclic AMP and theophylline on the melanosome transformation in the embryonic chick pigmented retina cultured in vitro.
Topics: Adenosine Monophosphate; Bucladesine; Cells, Cultured; Cyclic GMP; Cytoplasmic Granules; Retina; Retinal Pigments; Theophylline; Time Factors | 1976 |
Inhibition of "spontaneous," notochord-induced, and collagen-induced in vitro somite chondrogenesis by cyclic AMP derivatives and theophylline.
Topics: Animals; Bucladesine; Cartilage; Cells, Cultured; Chick Embryo; Collagen; Cyclic GMP; Depression, Chemical; Embryonic Induction; Mesoderm; Nervous System; Spine; Theophylline | 1976 |
Action of insulin and cell calcium: effect of ionophore A23187.
Topics: Animals; Anti-Bacterial Agents; Bucladesine; Caffeine; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Insulin; Membrane Potentials; Methylglucosides; Muscle Contraction; Muscles; Rats; Theophylline | 1976 |
The effect of cyclic nucleotides on vasopressin release from the isolated neural lobe of normal and dehydrated rats and the intact hypothalamo-neurohypophysial system.
Topics: Animals; Cyclic AMP; Cyclic GMP; Depression, Chemical; Hypothalamus; In Vitro Techniques; Pituitary Gland, Posterior; Rats; Theophylline; Vasopressins | 1976 |
Non-histone-protein phosphorylation in rat salivary glands after treatment with isoproterenol, dibutyryladenosine cyclic monophosphate and dibutyrylguanosine cyclic monophosphate.
Topics: Animals; Bucladesine; Chromosomal Proteins, Non-Histone; Cyclic GMP; Isoproterenol; Phosphoproteins; Rats; Salivary Glands; Theophylline | 1976 |
Platelet cyclic 3':5'-nucleotide phosphodiesterase released by thrombin and calcium ionophore.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Bacterial Agents; Blood Platelets; Calcimycin; Calcium; Cyclic GMP; Enzyme Activation; Heparin; Humans; Kinetics; Papaverine; Phosphoric Diester Hydrolases; Rats; Theophylline; Thrombin | 1976 |
Depolarizing media increase the guanosine 3',5'-monophosphate content of bovine superior cervical ganglion.
Topics: Animals; Azides; Cattle; Cyclic GMP; Ganglia, Autonomic; Ganglia, Spinal; Hydrazines; In Vitro Techniques; Nicotinic Acids; Phosphodiesterase Inhibitors; Potassium; Tetracaine; Tetrodotoxin; Theophylline; Veratridine | 1976 |
Evidence for a prejunctional role of cyclic nucleotides in neuromuscular transmission.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bucladesine; Cats; Cyclic AMP; Cyclic GMP; Fluorides; Membrane Potentials; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Nucleotides, Cyclic; Synaptic Transmission; Theophylline | 1976 |
The influence of prostaglandin G2 on platelet ultrastructure and platelet secretion.
Topics: Adenosine; Blood Platelets; Bucladesine; Calcimycin; Cyclic GMP; Edetic Acid; Ethylmaleimide; Humans; Phorbols; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Serotonin; Theophylline | 1977 |
Differential inhibition of cyclic AMP and cyclic GMP hydrolysis in rat renal cortex.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Azides; Carbachol; Cyclic AMP; Cyclic GMP; Kidney Cortex; Parathyroid Hormone; Phosphoric Diester Hydrolases; Rats; Theophylline; Xanthines | 1977 |
Role of cyclic nucleotides in human lymphocyte-mediated antibody-dependent cytotoxicity.
Topics: Acetylcholine; Antibodies; Bucladesine; Carbachol; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Depression, Chemical; Drug Synergism; Histamine; Humans; Isoproterenol; Lymphocytes; Prostaglandins E; Theophylline | 1977 |
Effects of diaminopropionate, deoxyadenosine, and theophylline on stimulated formation of cyclic AMP and GMP by depolarizing agents in slices of guinea-pig cerebral cortex.
Topics: Adenosine; Alanine; Amino Acids, Diamino; Animals; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cysteine; Deoxyadenosines; Glutamates; Guinea Pigs; Histamine; In Vitro Techniques; Male; Nucleotides, Cyclic; Ouabain; Potassium; Theophylline; Veratridine; Xanthines | 1977 |
Uptake and metabolism of cyclic AMP in rabbit choroid plexus in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Monophosphate; Animals; Choroid Plexus; Cyclic AMP; Cyclic GMP; Hypoxia; In Vitro Techniques; Kinetics; Male; Nitrogen; Ouabain; Pia Mater; Rabbits; Temperature; Theophylline | 1977 |
Rosette formation by human T and B lymphocytes in the presence of adrenergic and cholinergic drugs.
Topics: Atropine; Autonomic Agents; B-Lymphocytes; Bucladesine; Butyrates; Carbachol; Cyclic AMP; Cyclic GMP; Humans; Immunologic Techniques; Isoproterenol; Lymphocytes; Papaverine; Pilocarpine; Propranolol; T-Lymphocytes; Theophylline | 1976 |
Cyclic nucleotide phosphodiesterase activities of the fetal and mature human cerebral cortex.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Carrier Proteins; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Fetus; Humans; Hydrolysis; Kinetics; Male; Phosphoric Diester Hydrolases; Polyethylene Glycols; Pregnancy; Theophylline | 1977 |
Regulation of hypoxanthine transport by cyclic nucleotides in cultured Chinese hamster lung fibroblasts.
Topics: Bucladesine; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; DNA; Fibroblasts; Glucagon; Hydroxyurea; Hypoxanthines; Insulin; Nucleotides, Cyclic; Theophylline; Thymidine; Xanthines | 1977 |
Mediation of guinea pig gastric secretion in vitro by cyclic nucleotides.
Topics: Animals; Bucladesine; Butyrates; Cyclic GMP; Dose-Response Relationship, Drug; Duodenum; Gastric Mucosa; Gastrins; Guinea Pigs; Intestinal Mucosa; Methacholine Compounds; Secretory Rate; Theophylline | 1977 |
The influence of the calcium antagonist fendiline on tone and motility of the guinea pig gut smooth muscle and the cAMP and cGMP concentrations of the isolated terminal ileum.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Digestive System; Female; Gastrointestinal Motility; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Phenethylamines; Theophylline | 1977 |
Effects of db-cAMP and theophylline on Concanavalin A binding site distribution on transformed and protease-treated cell lines.
Topics: Adenosine; Adenosine Monophosphate; Bucladesine; Butyrates; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Concanavalin A; Cyclic GMP; Receptors, Concanavalin A; Receptors, Drug; Theophylline; Trypsin | 1977 |
Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors.
Topics: Adenosine; Blood Platelets; Caffeine; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dipyridamole; Humans; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phthalazines; Platelet Aggregation; Theophylline | 1977 |
Elevation of guanosine 3',5'-monophosphate level by adenosine in cerebellar slices of guinea pig.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cerebellum; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Papaverine; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1977 |
The accumulation of cyclic AMP and cyclic GMP in guinea pig brain slices. Effect of calcium ions, norepinephrine and adenosine.
Topics: Adenosine; Animals; Brain; Calcium; Cerebellum; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Mice; Norepinephrine; Organ Specificity; Rats; Species Specificity; Theophylline | 1977 |
Rat osteogenic sarcoma cells: isolation and effects of hormones on the production of cyclic AMP and cyclic GMP.
Topics: Adrenocorticotropic Hormone; Animals; Calcitonin; Cyclic AMP; Cyclic GMP; Glucagon; Glucose; Growth Hormone; Hormones; Insulin; Isoproterenol; Nucleotides, Cyclic; Osteosarcoma; Parathyroid Hormone; Prolactin; Prostaglandins; Rats; Theophylline; Thyroxine | 1977 |
Changes in radiosensitivity induced by cyclic nucleotides and chemical radioprotection.
Topics: 5-Methoxytryptamine; Animals; beta-Aminoethyl Isothiourea; Bucladesine; Cricetinae; Cyclic AMP; Cyclic GMP; Cystamine; Nucleotides, Cyclic; Radiation Tolerance; Radiation-Protective Agents; Theophylline | 1977 |
Effects of parathyroid hormone on cyclic AMP, cyclic GMP, and efflux of calcium in isolated renal tubules.
Topics: Animals; Calcium; Cricetinae; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Kidney Tubules; Male; Parathyroid Hormone; Theophylline | 1977 |
Cyclic AMP and cyclic GMP in the rat gastric mucosa. The significance of post mortem changes and tissue fixation on the estimation of the in vivo level.
Topics: Adenylyl Cyclases; Adrenalectomy; Animals; Cyclic AMP; Cyclic GMP; Dexamethasone; Epinephrine; Female; Fixatives; Gastric Mucosa; Methods; Microwaves; Phenoxybenzamine; Phosphoric Diester Hydrolases; Postmortem Changes; Propranolol; Rats; Temperature; Theophylline; Time Factors | 1977 |
Modulation of cyclic nucleotide levels in peripheral nerve without effect on resting or compound action potentials.
Topics: Action Potentials; Animals; Anura; Carbachol; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Rana pipiens; Sciatic Nerve; Theophylline | 1977 |
Cyclic nucleotide fluctuations during steroid induced meiotic maturation of frog oocytes.
Topics: Animals; Anura; Cyclic AMP; Cyclic GMP; Female; Meiosis; Nucleotides, Cyclic; Oocytes; Oogenesis; Ovum; Progesterone; Rana pipiens; Theophylline | 1977 |
[Effect of dibutyryl cyclic AMP and 8-bromo cyclic GMP on polynucleocyte chemotaxis in vivo in rats].
Topics: Animals; Bucladesine; Calcium; Chemotaxis; Cyclic GMP; Diphosphates; Neutrophils; Rats; Theophylline | 1977 |
Interaction between cyclic nucleotides and herpes simplex viruses: productive infection.
Topics: Bucladesine; Cell Line; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Insulin; Papaverine; Simplexvirus; Theophylline | 1977 |
Cyclic AMP and the mechanism of leucocyte lysosomal enzyme release during an immediate hypersensitivity reaction in vivo.
Topics: Animals; Arthus Reaction; Bucladesine; Colchicine; Cyclic AMP; Cyclic GMP; Glucuronidase; L-Lactate Dehydrogenase; Leukocytes; Lysosomes; Male; Rats; Theophylline | 1977 |
Effects of prostaglandins, derivatives of cyclic 3':5'-AMP, theophylline, cholinergic agents and colchicine on clot retraction in dilute platelet-rich plasma and gel-separated platelet test systems.
Topics: Blood Coagulation; Blood Platelets; Calcium; Clot Retraction; Colchicine; Cyclic AMP; Cyclic GMP; Humans; Parasympathomimetics; Platelet Aggregation; Prostaglandins; Serotonin; Theophylline | 1977 |
Effect of TSH on cAMP and cGMP levels in thyroid cancers, adenomas and normal human thyroid tissue.
Topics: Adenoma; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Neoplasm Metastasis; Theophylline; Thyroid Gland; Thyroid Neoplasms; Thyrotropin | 1978 |
A cAMP-induced increase in the motility of demembranated bull sperm models.
Topics: Adenosine Monophosphate; Animals; Bucladesine; Cattle; Cell Survival; Cyanides; Cyclic AMP; Cyclic GMP; Deoxyglucose; Male; Sperm Motility; Spermatozoa; Theophylline | 1978 |
Effects of factors released from eggs and other agents on cyclic nucleotide concentrations of sea urchin spermatozoa.
Topics: Animals; Calcimycin; Cyclic AMP; Cyclic GMP; Female; Male; Ovum; Sea Urchins; Spermatozoa; Theophylline; Tissue Extracts | 1978 |
The elevation of sperm adenosine 3',5'-monophosphate concentrations by factors released from eggs requires calcium.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Magnesium; Male; Ovum; Sea Urchins; Spermatozoa; Stimulation, Chemical; Theophylline | 1978 |
Effects of theophylline and N6,O2-dibutyryl adenosine 3':5'-monophosphate on sympathetic ganglionic transmission in rats.
Topics: Acetylcholine; Animals; Bucladesine; Cyclic GMP; Electric Stimulation; Ganglia, Autonomic; In Vitro Techniques; Male; Membrane Potentials; Rats; Synaptic Transmission; Theophylline | 1978 |
The role of cyclic nucleotides in the regulation of mitotic activity in SSPE virus-infected human brain tissue.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bucladesine; Cell Line; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Imidazoles; Mitosis; Papaverine; Theophylline | 1978 |
The generation and regulation of lymphocyte populations: evidence from differentiative induction systems in vitro.
Topics: Animals; B-Lymphocytes; Cell Differentiation; Cell Separation; Cyclic AMP; Cyclic GMP; Endotoxins; Epinephrine; Imidazoles; Isoproterenol; Lymphocytes; Mice; Peptides; Poly A-U; Propranolol; Prostaglandins E; T-Lymphocytes; Theophylline; Thymopoietins | 1978 |
Effect of cyclic nucleotides on mitogen. Responsiveness of lymphocytes from patients undergoing dialysis.
Topics: Bucladesine; Cyclic GMP; Drug Synergism; Humans; Kidney Failure, Chronic; Lectins; Lymphocyte Activation; Mitogens; Renal Dialysis; Theophylline | 1978 |
Urinary excretion of cyclic adenosine 3',5'-monophosphate and cyclic guanosine 3',5'-monophosphate in malignancy.
Topics: Adult; Aged; Cyclic AMP; Cyclic GMP; Female; Glucagon; Humans; Male; Middle Aged; Neoplasms; Theophylline | 1978 |
The role of cyclic GMP in the action of carbamylcholine on the cycli AMP level in the dog thyroid.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; In Vitro Techniques; Kinetics; Prostaglandins F; Theophylline; Thyroid Gland; Thyrotropin | 1978 |
The phosphorylation of salivary gland chromatin proteins following treatment of rats with dibutyryl cyclic AMP and dibutyryl cyclic GMP.
Topics: Animals; Bucladesine; Chromatin; Cyclic GMP; Dibutyryl Cyclic GMP; DNA; Female; Parotid Gland; Phosphorylation; Rats; Salivary Glands; Submandibular Gland; Theophylline | 1978 |
Neurotransmitter and cyclic nucleotide modulation of frog cardiac contractility.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Anura; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Epinephrine; Heart; Myocardial Contraction; Myocardium; Rana pipiens; Theophylline | 1978 |
Regulation of the calcium sensitivity of the contractile system of heart muscle by the sarcolemma.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Cyclic GMP; Cytidine Triphosphate; In Vitro Techniques; Muscle Proteins; Myocardial Contraction; Phosphorylation; Sarcolemma; Theophylline | 1978 |
Effect of adenosine 3':5'-monophosphate and guanosine 3':5'-monophosphate on RNA release from isolated nuclei.
Topics: Animals; Cell Nucleus; Cyclic AMP; Cyclic GMP; Fluorides; Kinetics; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Molecular Weight; Rats; RNA; Theophylline | 1978 |
Effects of secretagogues and theophylline on canine gastric mucosal cyclic nucleotides.
Topics: Animals; Bethanechol Compounds; Cyclic AMP; Cyclic GMP; Dogs; Drug Synergism; Female; Gastric Mucosa; Histamine; Kinetics; Male; Pentagastrin; Theophylline | 1978 |
The effect of cGMP in rabbit auricle as studied by a cut-end method.
Topics: Action Potentials; Animals; Cyclic GMP; Heart; In Vitro Techniques; Myocardial Contraction; Potassium Chloride; Rabbits; Theophylline | 1978 |
Cholinergic mechanisms and short-term potentiation.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Cyclic GMP; Electric Stimulation; Evoked Potentials; Hippocampus; Neural Pathways; Physostigmine; Potassium; Rabbits; Septum Pellucidum; Synapses; Synaptic Transmission; Theophylline | 1977 |
In vitro tropic action of ACTH upon adrenocortical cyclic nucleotide (cAMP, cGMP) production and corticosterone output in blue (Prionace glauca Linnaeus) and in mako (Isurus oxyrinchus Rafinesque) sharks.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Sharks; Theophylline | 1978 |
[The effects of various vitamin D metabolites on the secretion of parathyroid hormone in monolayer cultures of bovine parathyroid cells (author's transl)].
Topics: Animals; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dihydroxycholecalciferols; Hydroxycholecalciferols; Parathyroid Glands; Parathyroid Hormone; Prostaglandins E; Theophylline | 1979 |
The action of adenosine on steroidogenesis in isolated rat adrenocortical cells.
Topics: Adenine Nucleotides; Adenosine; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Rats; Steroids; Theophylline | 1978 |
Cyclic nucleotides, cyclic nucleotide phosphodiesterase, and development in Myxococcus xanthus.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Cyclic AMP; Cyclic GMP; Glycerol; Isoleucine; Methionine; Myxococcales; Phosphates; Phosphoric Diester Hydrolases; Theophylline; Threonine | 1978 |
Comparative study of cholinergic control of cyclic nucleotides levels in pig and dog thyroid.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Kinetics; Species Specificity; Swine; Theophylline; Thyroid Gland; Thyrotropin | 1979 |
Effect of cold treatment and some drugs on the 5-hydroxytryptamine uptake by rabbit blood platelets and their ultrastructure.
Topics: Animals; Blood Platelets; Colchicine; Cold Temperature; Cyclic AMP; Cyclic GMP; Cytochalasin B; Female; In Vitro Techniques; Male; Poloxalene; Rabbits; Serotonin; Theophylline; Vinblastine | 1979 |
Apparent irrelevance of cyclic nucleotides to the relaxation of tracheal smooth muscle induced by theophylline.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Dogs; Guinea Pigs; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Theophylline; Trachea | 1979 |
Factors promoting colony stimulating activity (CSA) production in macrophages and epithelial cells.
Topics: Animals; Ascitic Fluid; Blood; Cells, Cultured; Colony-Stimulating Factors; Complement C3; Complement C5; Cyclic AMP; Cyclic GMP; Cycloheximide; Endotoxins; Epithelial Cells; Epithelium; Inulin; Latex; Lithium; Macrophages; Mice; Microspheres; Theophylline; Thymus Gland; Zymosan | 1979 |
Trials with xanthine derivatives in systemic treatment of psoriasis.
Topics: Adolescent; Adult; Aged; Aminophylline; Child; Cyclic AMP; Cyclic GMP; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Psoriasis; Skin; Theophylline | 1979 |
Starfish and horseshoe crab egg factors cause elevations of cyclic nucleotide concentrations in spermatozoa from starfish and horseshoe crabs.
Topics: Animals; Cyclic AMP; Cyclic GMP; Female; Fertilization; Horseshoe Crabs; Male; Ovum; Sea Urchins; Species Specificity; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Starfish; Theophylline | 1979 |
Influence of theophylline on concentrations of cyclic 3',5'-adenosine monophosphate and cyclic 3',5'-guanosine monophosphate of rat brain.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Brain; Cyclic AMP; Cyclic GMP; Female; Rats; Theophylline | 1979 |
Cyclic nucleotides in the rat neostriatum: push-pull perfusion studies.
Topics: Animals; Caudate Nucleus; Corpus Striatum; Cyclic AMP; Cyclic GMP; Dopamine; Dose-Response Relationship, Drug; Male; Pimozide; Rats; Theophylline | 1979 |
Acid secretion and mucosal cyclic nucleotide content of the guinea pig isolated stomach during bethanechol stimulation.
Topics: Animals; Bethanechol Compounds; Carbachol; Cyclic AMP; Cyclic GMP; Gastric Juice; Gastric Mucosa; Guinea Pigs; Stimulation, Chemical; Theophylline | 1979 |
On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; Guinea Pigs; Hydrolysis; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaverine; Theophylline; Trachea | 1979 |
Correlation of cyclic AMP and cyclic GMP levels with changes in contractile force of dog ventricular myocardium during cholinergic antagonism of positive inotropic actions of histamine, glucagon, theophylline and papaverine.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Female; Glucagon; Heart Ventricles; Histamine Antagonists; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Papaverine; Stimulation, Chemical; Theophylline | 1979 |
Cyclic 3',5'-adenosine monophosphate phosphodiesterase (cAMP PDE) and cyclic 3',5'-guanosine monophosphate phosphodiesterase (cGMP PDE) in microvessels isolated from bovine cortex.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Calcium; Cattle; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Imidazoles; Magnesium; Microcirculation; Theobromine; Theophylline | 1979 |
Metabolism of cyclic nucleotides in allergic rhinitis: studies on lymphocytes, granulocytes, and plasma level.
Topics: Adolescent; Adult; Asthma; Child; Cyclic AMP; Cyclic GMP; Granulocytes; Humans; Isoproterenol; Lymphocytes; Middle Aged; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Theophylline | 1979 |
Muscarinic cholinergic stimulation increases cyclic GMP levels in rat hippocampus.
Topics: Animals; Atropine; Bethanechol Compounds; Calcium; Cyclic GMP; Female; Hippocampus; Kinetics; Male; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Theophylline | 1979 |
Comparison of the effects of biogenic amines on cyclic GMP and cycle AMP levels in mouse cerebellum in vitro.
Topics: Adenosine; Animals; Biogenic Amines; Brain Chemistry; Calcium; Cerebellum; Culture Media; Cyclic AMP; Cyclic GMP; Dopamine; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Histamine; Male; Mice; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium; Receptors, Adrenergic; Serotonin; Theophylline; Tyrosine | 1975 |
Properties of guanylate cyclase and levels of cyclic GMP in rat small intestinal villous and crypt cells.
Topics: Adenine Nucleotides; Alloxan; Amino Acids; Animals; Anti-Bacterial Agents; Carboxylic Acids; Cyclic GMP; Epinephrine; Fluorides; Glucose; Guanosine Triphosphate; Guanylate Cyclase; Intestinal Mucosa; Intestine, Small; Kinetics; Manganese; Oxaloacetates; Phosphoenolpyruvate; Polyethylene Glycols; Prostaglandins; Rats; Theophylline | 1975 |
Effects of 6- and 8-substituted analogs of adenosine 3':5'-monophosphate on phosphoenolpyruvate carboxykinase and tyrosine aminotransferase in hepatoma cell cultures.
Topics: Animals; Butyrates; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cyclic AMP; Cyclic GMP; Enzyme Activation; Inosine Nucleotides; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorus Radioisotopes; Protein Kinases; Rats; Structure-Activity Relationship; Theophylline; Time Factors; Tritium; Tyrosine Transaminase | 1975 |
Effect of cyclic nucleotides and phosphodiesterase inhibition on morphine tolerance and physical dependence.
Topics: Adrenergic beta-Antagonists; Animals; Cyclic AMP; Cyclic GMP; Cycloheximide; Drug Tolerance; Humans; Mice; Morphine; Naloxone; Phosphodiesterase Inhibitors; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline | 1975 |
Role of cyclic AMP in differentiation of human neuroblastoma cells in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bucladesine; Butyrates; Cell Differentiation; Cell Line; Cell Survival; Cyclic AMP; Cyclic GMP; Humans; Imidazoles; Neuroblastoma; Papaverine; Prostaglandin Antagonists; Prostaglandins E; Radiation Effects; Theophylline; Tyrosine 3-Monooxygenase | 1975 |
Factors released from sea urchin eggs affect cyclic nucleotide metabolism in sperm.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Guanylate Cyclase; Male; Ovum; Sea Urchins; Spermatozoa; Theophylline | 1975 |
Effects of intracellular cyclic AMP and cyclic GMP levels on DNA synthesis of young-adult rat hepatocytes in primary culture.
Topics: Age Factors; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dipyridamole; DNA; In Vitro Techniques; Liver; Male; Rats; Theophylline | 1992 |
Cyclic nucleotide phosphodiesterases from frog atrial fibers: isolation and drug sensitivities.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium Chloride; Calmodulin; Chromatography, Ion Exchange; Cyclic GMP; Cytosol; Dipyridamole; Heart Atria; Heart Ventricles; Kinetics; Myocardium; Papaverine; Purinones; Pyrrolidinones; Rana esculenta; Rana ridibunda; Rolipram; Substrate Specificity; Theophylline | 1992 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
The role of intrarenal adenosine in glomerular action of atrial natriuretic factor.
Topics: Adenosine; Adenosine Deaminase; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dipyridamole; Glucagon; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Saralasin; Sodium; Theophylline | 1991 |
17 beta-estradiol depolarization of hypothalamic neurons is mediated by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Drug Implants; Electric Conductivity; Estradiol; Female; Guinea Pigs; Hypothalamus; Imidazoles; Membrane Potentials; Neurons; Ovariectomy; Potassium; Theophylline | 1990 |
cAMP analogs and selective inhibitors used to study low Km Mucor rouxii cAMP phosphodiesterase.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Centrifugation, Density Gradient; Cyclic AMP; Cyclic GMP; Dipyridamole; Hydrolysis; Mucor; Nicotinic Acids; Papaverine; Pyridazines; Theophylline | 1990 |
Stimulants of ileal salt transport in neuroendocrine system of the desert locust.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Central Nervous System; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Ganglia; Grasshoppers; Ileum; Insect Hormones; Neurosecretory Systems; Neurotransmitter Agents; Peptide Hydrolases; Potassium Chloride; Proteins; Rectum; Second Messenger Systems; Temperature; Theophylline; Time Factors; Tissue Extracts | 1990 |
Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cell Line; Chlorides; Cyclic AMP; Cyclic GMP; Cytosol; Electrolytes; Epithelium; Histamine; Humans; Inflammation; Kinetics; Phenylisopropyladenosine; Phosphorylation; Protein Kinases; Theophylline | 1990 |
Attenuated glomerular responses to atrial natriuretic factor in low-sodium rats is prevented by theophylline.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cyclic GMP; Glomerular Filtration Rate; Kidney Glomerulus; Male; Phosphodiesterase I; Phosphoric Diester Hydrolases; Rats; Rats, Inbred Strains; Sodium; Theophylline | 1990 |
Pharmacogenetics of cyclic guanylate, antioxidants, and antioxidant enzymes in Neurospora.
Topics: Aging; Antioxidants; Cell Differentiation; Culture Media; Cyclic GMP; Free Radicals; Gene Expression Regulation, Enzymologic; Hydroxides; Hydroxyl Radical; Mutation; Neurospora; Second Messenger Systems; Superoxide Dismutase; Theophylline | 1990 |
Pharmacogenetics of cyclic guanylate, antioxidants, and antioxidant enzymes in Saccharomyces.
Topics: Antioxidants; Catalase; Cell Differentiation; Copper; Cyclic GMP; Drug Resistance, Microbial; Free Radicals; Iron; Lighting; Mutation; Oxygen; Paraquat; Saccharomyces; Superoxide Dismutase; Theophylline; Vitamin E | 1990 |
Isoprenaline-like effects of the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine on mechanical, biochemical and electrophysiological parameters in the mammalian heart.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Calcium; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Myocardial Contraction; Stimulation, Chemical; Theophylline | 1985 |
Influence of papaverine on cyclic nucleotide level and cellular metabolism in rat kidney cortex in terms of its inhibitory effect on p-aminohippurate transport.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Aminohippuric Acids; Animals; Biological Transport; Calcium; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Kidney Cortex; Male; Mitochondria; Nucleotides, Cyclic; Ouabain; Oxygen Consumption; p-Aminohippuric Acid; Papaverine; Rats; Rats, Inbred Strains; Sodium; Theophylline | 1986 |
Steroid regulation of the peptide-mediated increase in cyclic GMP in the nervous system of the hawkmoth, Manduca sexta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Ganglia; Insect Hormones; Lepidoptera; Moths; Theophylline | 1985 |
The in vitro effects of cyclic nucleotides, cyanoketone, and cycloheximide on the production of estradiol-17 beta by vitellogenic ovarian follicles of goldfish (Carassius auratus).
Topics: 1-Methyl-3-isobutylxanthine; Androstenols; Animals; Aromatase; Bucladesine; Chorionic Gonadotropin; Cyanoketone; Cyclic AMP; Cyclic GMP; Cycloheximide; Cyprinidae; Dibutyryl Cyclic GMP; Estradiol; Female; Goldfish; Nucleotides, Cyclic; Ovarian Follicle; Theophylline; Time Factors; Vitellogenesis | 1986 |
Effects of cyclic nucleotide derivatives on acetylcholine-induced secretion from isolated, perfused rat submandibular salivary glands.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Bucladesine; Cyclic GMP; Isoproterenol; Male; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Saliva; Submandibular Gland; Theophylline | 1986 |
Effects of temperature on allosteric and catalytic properties of the cGMP-stimulated cyclic nucleotide phosphodiesterase from calf liver.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cattle; Cyclic AMP; Cyclic GMP; Kinetics; Liver; Solvents; Temperature; Theophylline | 1987 |
Effects of enoximone and isobutylmethylxanthine on contractile tension and cyclic nucleotide levels in isolated blood-perfused dog papillary muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Dogs; Enoximone; Imidazoles; In Vitro Techniques; Myocardial Contraction; Nucleotides, Cyclic; Papillary Muscles; Theophylline | 1987 |
Opposite regulatory effects of cAMP and cGMP on sugar uptake in rat thymocytes.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Carbohydrate Metabolism; Cyclic AMP; Cyclic GMP; Deoxyglucose; Epinephrine; Female; Insulin; Osmolar Concentration; Rats; Rats, Inbred Strains; Theophylline; Thymus Gland; Triiodothyronine | 1987 |
Effects of IBMX on the ERG of the isolated perfused cat eye.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Electroretinography; In Vitro Techniques; Photometry; Photoreceptor Cells; Retina; Theophylline; Time Factors | 1987 |
Differences in the cyclic nucleotide mediation of luteinizing hormone-releasing hormone action on the rat and hamster anterior pituitary gland.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cricetinae; Cyclic GMP; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; In Vitro Techniques; Kinetics; Luteinizing Hormone; Male; Mesocricetus; Pituitary Gland, Anterior; Rats; Species Specificity; Theophylline | 1988 |
3':5'-cyclic GMP in the yeast Saccharomyces cerevisiae at different metabolic conditions.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic AMP; Cyclic GMP; Glucose; Guanosine Triphosphate; Oxygen; Radioimmunoassay; Saccharomyces cerevisiae; Theophylline | 1988 |
Adenosine inhibits the positive inotropic effect of 3-isobutyl-1-methylxanthine in papillary muscles without effect on cyclic AMP or cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenosine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylisopropyladenosine; Theophylline | 1988 |
Excitation of locus coeruleus neurons by an adenosine 3',5'-cyclic monophosphate-activated inward current: extracellular and intracellular studies in rat brain slices.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Rats; Reference Values; Theophylline | 1987 |
Attenuation of endotoxin-induced cytotoxicity and prostacyclin production in cultured bovine pulmonary artery endothelial cells by phosphodiesterase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Adenylyl Cyclases; Animals; Bucladesine; Cattle; Cell Survival; Cells, Cultured; Colforsin; Cyclic GMP; Endothelium, Vascular; Ferricyanides; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitroprusside; Phosphodiesterase Inhibitors; Pulmonary Artery; Theophylline | 1988 |
On the transduction mechanism of microvillar photoreceptors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cyclic GMP; Dark Adaptation; Invertebrates; Ion Channels; Membrane Potentials; Microvilli; Phosphorylation; Photoreceptor Cells; Signal Transduction; Theophylline | 1989 |
A study of the phasic response of arterioles of the guinea pig small intestine to prolonged exposure to norepinephrine.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arterioles; Clonidine; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Isoproterenol; Membrane Potentials; Norepinephrine; Oxidation-Reduction; Propranolol; Temperature; Theophylline; Vasoconstriction; Yohimbine | 1989 |
Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Carbamates; Cardiovascular Agents; Cyclic AMP; Cyclic GMP; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Rabbits; Theophylline | 1989 |
Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22,948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Kinetics; Male; Methylene Blue; Muscle Relaxants, Central; Nitric Oxide; Phthalazines; Purinones; Pyridazines; Rats; Rats, Inbred Strains; Theophylline; Vinca Alkaloids | 1989 |
Resolution of soluble cyclic nucleotide phosphodiesterase isoenzymes, from liver and hepatocytes, identifies a novel IBMX-insensitive form.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium; Calmodulin; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Cytosol; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Sodium nitroprusside and guanosine 3',5'-monophosphate (cyclic GMP) inhibit stimulated phosphoinositide hydrolysis in rat cerebral cortical slices.
Topics: Animals; Carbachol; Cerebral Cortex; Cyclic GMP; Ferricyanides; In Vitro Techniques; Male; Nitroprusside; Phosphatidylinositols; Rats; Rats, Inbred Strains; Theophylline | 1989 |
cGMP-induced differentiation of the promyelocytic cell line HL-60.
Topics: Cell Differentiation; Cell Line; Cyclic AMP; Cyclic GMP; Flow Cytometry; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nitroprusside; Second Messenger Systems; Sodium Nitrite; Theophylline | 1989 |
Pacemaker activity is modulated by tissue levels of cyclic adenosine 3',5'-monophosphate in human atrial fibers.
Topics: Action Potentials; Adult; Atrial Function; Child, Preschool; Cyclic AMP; Cyclic GMP; Epinephrine; Female; Heart Atria; Heart Conduction System; Heart Defects, Congenital; Heart Diseases; Heart Rate; Humans; In Vitro Techniques; Male; Middle Aged; Theophylline | 1989 |
A possible mechanism of action of tetramethylpyrazine on vascular smooth muscle in rat aorta.
Topics: Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Potassium; Pyrazines; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1989 |
Further studies on the influence of cyclic nucleotides on junctional permeability in heart.
Topics: Acetylcholine; Animals; Bucladesine; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Dogs; Heart; In Vitro Techniques; Intercellular Junctions; Isoquinolines; Mathematics; Theophylline | 1987 |
Na+-dependent elevation of the acidic cell surface pH (microclimate pH) of rat jejunal villus cells induced by cyclic nucleotides and phorbol ester: possible mediators of the regulation of the Na+/H+ antiporter.
Topics: Amiloride; Animals; Bucladesine; Calcimycin; Carrier Proteins; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Hydrogen-Ion Concentration; Jejunum; Male; Microvilli; Phorbol Esters; Phorbols; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Theophylline | 1988 |
Cyclic nucleotides and suppression of follicle-stimulating hormone release by inhibin.
Topics: Animals; Calmodulin; Cells, Cultured; Cyclic AMP; Cyclic GMP; Female; Follicle Stimulating Hormone; Gonadotropins; Inhibins; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Theophylline | 1987 |
Effects of sera types and cell density on the concentration of cyclic nucleotides in normal and simian virus transformed mouse fibroblasts.
Topics: Animals; Bucladesine; Cell Division; Cell Transformation, Viral; Cells, Cultured; Cyclic AMP; Cyclic GMP; Fibroblasts; Mice; Simian virus 40; Theophylline | 1987 |
The effect of heat-stable Escherichia coli enterotoxin, theophylline and forskolin on cyclic nucleotide levels and mucosal surface (acid microclimate) pH in rat proximal jejunum in vivo.
Topics: Animals; Bacterial Toxins; Colforsin; Cyclic AMP; Cyclic GMP; Electric Conductivity; Enterotoxins; Escherichia coli Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Rats; Rats, Inbred Strains; Reference Values; Theophylline | 1988 |
Adenosine stimulates guanylate cyclase activity in vascular smooth muscle cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Theophylline; Time Factors | 1987 |
The effect of Escherichia coli STa enterotoxin and other secretagogues on mucosal surface pH of rat small intestine in vivo.
Topics: Animals; Bacterial Toxins; Cholera Toxin; Colforsin; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Jejunum; Kinetics; Male; Microelectrodes; Perfusion; Rats; Rats, Inbred Strains; Reference Values; Theophylline | 1988 |
Effects of theophylline, beta-adrenergic stimulants and prednisolone on platelet and urine cyclic guanosine monophosphate (cGMP).
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Aminophylline; Asthma; Blood Platelets; Cyclic GMP; Ethanolamines; Female; Humans; Isoproterenol; Male; Middle Aged; Prednisolone; Procaterol; Theophylline | 1988 |
[The effect of phosphodiesterase inhibitors on retinal function of the eye undergoing arterial perfusion].
Topics: Animals; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Electroretinography; Female; Imidazoles; Male; Perfusion; Phosphodiesterase Inhibitors; Photoreceptor Cells; Retina; Theophylline | 1985 |
Drug effects on the hydraulic conductivity of the isolated rabbit ciliary epithelium.
Topics: Amiloride; Animals; Body Fluids; Ciliary Body; Cyclic GMP; Epithelium; Ethacrynic Acid; Ferricyanides; Furosemide; In Vitro Techniques; Rabbits; Sympathomimetics; Theophylline | 1985 |
Cyclic AMP and theophylline enhance DNA synthesis in L cells stimulated with anti-actin IgG and [(IgG)2 protein A]2 complex by recruiting cells into S-phase.
Topics: Actins; Animals; Cyclic AMP; Cyclic GMP; DNA; Immunoglobulin G; Interphase; L Cells; Mice; Staphylococcal Protein A; Theophylline | 1985 |
Local changes in fractional saturation of cGMP- and cAMP-receptors in intestinal microvilli in response to cholera toxin and heat-stable Escherichia coli toxin.
Topics: Animals; Bacterial Toxins; Carrier Proteins; Cholera Toxin; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Ileum; Intracellular Signaling Peptides and Proteins; Jejunum; Kinetics; Male; Microvilli; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cyclic AMP; Theophylline | 1986 |
[Stimulation of cyclic AMP and cyclic GMP in rat pancreas stimulated by gastro-intestinal hormones in vivo and in vitro].
Topics: Animals; Carbamates; Ceruletide; Cholecystokinin; Choline; Cyclic AMP; Cyclic GMP; Pancreas; Peptides; Pilocarpine; Radioimmunoassay; Rats; Secretin; Theophylline | 1974 |
Does cyclic-3',5'-AMP induce glutamine synthetase in embryonic neural retina?
Topics: Animals; Chick Embryo; Chromatography, Paper; Colorimetry; Cyclic AMP; Cyclic GMP; Enzyme Induction; Epinephrine; Glutamate-Ammonia Ligase; Hydrocortisone; Norepinephrine; Organ Culture Techniques; Retina; Theophylline | 1973 |
The effect of some nucleotides and related compounds on sodium transport and water permeability of the urinary bladder of the toad.
Topics: Adenine; Animals; Biological Transport; Bufo marinus; Cyclic AMP; Cyclic GMP; Electrochemistry; Hydrogen-Ion Concentration; In Vitro Techniques; Nucleotides; Permeability; Phosphodiesterase Inhibitors; Sodium; Theophylline; Urinary Bladder; Vasopressins; Water | 1973 |
Neutral protease release from human leukocytes regulated by neurohormones and cyclic nucleotides.
Topics: Acetylcholine; Atropine; Bucladesine; Choline; Cyclic AMP; Cyclic GMP; Epinephrine; Glucuronidase; Humans; Leukocytes; Neurotransmitter Agents; Norepinephrine; Peptide Hydrolases; Phenylephrine; Pilocarpine; Propranolol; Protease Inhibitors; Stimulation, Chemical; Theophylline | 1973 |
Hormonal control of lysosomal enzyme release from human neutrophils: elevation of cyclic nucleotide levels by autonomic neurohormones.
Topics: Acetylcholine; Atropine; Cyclic AMP; Cyclic GMP; Drug Antagonism; Epinephrine; Glucuronidase; Humans; L-Lactate Dehydrogenase; Lysosomes; Neurotransmitter Agents; Neutrophils; Phentolamine; Propranolol; Stimulation, Chemical; Theophylline; Zymosan | 1974 |
Guanosine cyclic 3',5'-monophosphate and guanylate cyclase activity in guinea pig lung: effects of acetylcholine and cholinesterase inhibitors.
Topics: Acetylcholine; Animals; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Edrophonium; Epinephrine; Female; Guanylate Cyclase; Guinea Pigs; Isoproterenol; Lung; Neostigmine; Phentolamine; Physostigmine; Propranolol; Prostaglandins; Serotonin; Theophylline; Time Factors; Tritium | 1974 |
Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. 1. Adenylate and guanylate cyclases.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Bivalvia; Bucladesine; Caffeine; Cyclic AMP; Cyclic GMP; Dopamine; Guanylate Cyclase; Heart; Myocardium; Protein Binding; Serotonin; Stimulation, Chemical; Temperature; Theophylline; Tritium | 1974 |
Glucose inhibition of epinephrine stimulation of hepatic gluconeogenesis by blockade of the alpha-receptor function.
Topics: Adrenergic alpha-Antagonists; Animals; Cyclic AMP; Cyclic GMP; Epinephrine; Fructose-Bisphosphatase; Fructosephosphates; Glucagon; Gluconeogenesis; Glucose; Guanine Nucleotides; In Vitro Techniques; Isoproterenol; Kinetics; Lactates; Liver; Phenoxybenzamine; Phosphofructokinase-1; Propranolol; Pyruvates; Rats; Stimulation, Chemical; Theophylline | 1974 |
Mechanism of action of some bronchodilators. Cyclic nucleotide metabolism in tracheal preparations.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Atropine; Bronchodilator Agents; Carbachol; Choline; Cyclic AMP; Cyclic GMP; Diphenhydramine; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Phenoxybenzamine; Phenylephrine; Practolol; Propranolol; Prostaglandins; Serotonin; Theophylline; Time Factors; Trachea | 1974 |
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes.
Topics: Adenine Nucleotides; Amidohydrolases; Animals; Cathepsins; Chloroquine; Colchicine; Culture Techniques; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dimethyl Sulfoxide; Glucuronidase; Humans; Hydrolases; L-Lactate Dehydrogenase; Leukocytes; Lysosomes; Macrophages; Mice; Phagocytosis; Prostaglandins; Stimulation, Chemical; Sulfatases; Theophylline; Vinblastine; Zymosan | 1971 |
Stimulation of adenosine 3',5'-monophosphate hydrolysis by guanosine 3',5'-monophosphate.
Topics: Adenine Nucleotides; Animals; Brain; Cattle; Cell Fractionation; Chemical Precipitation; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Guanine Nucleotides; Heart; Kidney; Kinetics; Liver; Male; Myocardium; Nucleotides; Phosphoric Monoester Hydrolases; Quaternary Ammonium Compounds; Rats; Stimulation, Chemical; Sulfates; Surface-Active Agents; Theophylline; Thymus Gland; Tritium | 1971 |
The possible role of cyclic AMP in some actions of cholera toxin.
Topics: Animals; Chick Embryo; Cholera; Cyclic AMP; Cyclic GMP; Dogs; Enterotoxins; Fetal Heart; In Vitro Techniques; Insulin; Intestinal Mucosa; Intestinal Secretions; Jejunum; Muscle Contraction; Stimulation, Chemical; Theophylline | 1971 |
A role of cyclic nucleotides in brain metabolism.
Topics: Adenosine Triphosphate; Animals; Brain; Cyclic AMP; Cyclic GMP; Electroshock; Glucosyltransferases; Glycogen; Kinetics; Mice; Papaverine; Phenobarbital; Phosphoric Monoester Hydrolases; Phosphotransferases; Rats; Theophylline | 1970 |
Prostaglandin E 1 effects on adenosine 3':5'-cyclic monophosphate concentration and phosphodiesterase activity in fibroblasts (mouse L cells-tissue culture-enzyme kinetics-prostaglandin homologues).
Topics: Animals; Cells, Cultured; Chromatography, Ion Exchange; Culture Media; Cyclic AMP; Cyclic GMP; Fibroblasts; In Vitro Techniques; L Cells; Mice; Phosphoric Monoester Hydrolases; Prostaglandins; Stimulation, Chemical; Theophylline; Time Factors | 1972 |
Cyclic nucleotide phosphodiesterase: high activity in a mammalian photoreceptor.
Topics: Animals; Brain; Butyrates; Caffeine; Cattle; Centrifugation, Density Gradient; Chickens; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Hydrolysis; Kinetics; Papaverine; Phosphoric Monoester Hydrolases; Photoreceptor Cells; Rats; Retina; Theophylline; Uracil Nucleotides | 1972 |
Cyclic 3'5'adenosine monophosphate inhibition of sulfation factor activity.
Topics: Animals; Blood Proteins; Cartilage; Chick Embryo; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Depression, Chemical; Inosine Nucleotides; Rats; Somatomedins; Sulfates; Sulfur Isotopes; Theophylline; Uracil Nucleotides | 1972 |
Phosphodiesterase activity of rat and human adipose tissue.
Topics: Adipose Tissue; Animals; Brain; Butyrates; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Epididymis; Hot Temperature; Hydrocortisone; Hydrogen-Ion Concentration; Hydrolysis; Inosine Nucleotides; Male; Omentum; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Theophylline; Thymine Nucleotides; Thyroxine; Uracil Nucleotides | 1972 |
Effects of acidosis and alkalosis on 3',5'-GMP and 3',5'-AMP in renal cortex.
Topics: Acidosis; Acute Disease; Alkalosis; Animals; Bicarbonates; Cyclic AMP; Cyclic GMP; Kidney; Lung; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Sodium Chloride; Theophylline | 1972 |
Heterogeneity of 3',5'-phosphodiesterase of gastric mucosa.
Topics: Animals; Cyclic AMP; Cyclic GMP; Gastric Mucosa; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Theophylline; Urodela | 1972 |
The effect of prostaglandins on ox pituitary content of adenosine 3':5'-cyclic monophosphate and the release of growth hormone.
Topics: Animals; Calcium; Cattle; Colchicine; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Growth Hormone; In Vitro Techniques; Inosine Nucleotides; Microtubules; Perchlorates; Pituitary Gland; Prostaglandins; Protein Binding; Proteins; Radioimmunoassay; Theophylline; Time Factors; Trichloroacetic Acid; Tritium | 1972 |
The effect of cyclic adenosine- and guanosine 3',5'-monophosphate on the normal and drug-increased coronary blood flow.
Topics: Adenosine; Animals; Aorta; Benzyl Compounds; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Cyclic AMP; Cyclic GMP; Dogs; Epinephrine; Lipid Metabolism; Muscle, Smooth; Theophylline; Vasodilator Agents | 1972 |
1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases.
Topics: Adrenal Glands; Ammonium Sulfate; Animals; Brain; Caffeine; Carboxylic Acids; Cats; Cattle; Cyclic AMP; Cyclic GMP; Esters; Hydrazines; Hydrolysis; In Vitro Techniques; Kinetics; Male; Myocardium; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazoles; Pyridines; Rats; Theophylline | 1972 |
Adenosine 3',5'-monophosphate: electrophysiological evidence for a role in synaptic transmission.
Topics: Animals; Cyclic AMP; Cyclic GMP; Dopamine; Ganglia, Autonomic; Membrane Potentials; Prostaglandins; Rabbits; Synaptic Transmission; Theophylline | 1972 |
Characterization of two forms of beef heart cyclic nucleotide phosphodiesterase.
Topics: Adenosine; Aminohydrolases; Ammonium Sulfate; Animals; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Electrophoresis, Disc; Kinetics; Molecular Weight; Myocardium; Nucleotidases; Nucleotides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Theophylline; Tritium; Ultracentrifugation | 1972 |
Cyclic AMP and citric acid accumulation by Aspergillus niger.
Topics: Adenine Nucleotides; Adenosine; Aspergillus; Citrates; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Sucrose; Theophylline; Time Factors | 1973 |
Effects of 3',5'-cyclic nucleotides on adrenocortical cells of hypophysectomized rats. A stereologic and autoradiographic study.
Topics: Adrenal Glands; Animals; Autoradiography; Cyclic AMP; Cyclic GMP; Hypophysectomy; Male; Microscopy, Electron; Mitochondria; Organ Size; Rats; RNA; Theophylline; Tritium; Uridine | 1973 |
Inhibition of metabolic effects of growth hormone by various inhibitors of cyclic nucleotide phosphodiesterase.
Topics: Aminobutyrates; Animals; Biological Transport; Carbon Isotopes; Cyclic AMP; Cyclic GMP; Diaphragm; Female; Glucose; Growth Hormone; Histamine; Histidine; Hypophysectomy; Imidazoles; Insulin; Leucine; Papaverine; Phosphodiesterase Inhibitors; Pituitary Gland; Protein Biosynthesis; Quinine; Rats; Theophylline; Tritium | 1973 |
Pleiotypic control by cyclic AMP: interaction with cyclic GMP and possible role of microtubules.
Topics: Animals; Biological Transport; Cell Line; Colchicine; Cyclic AMP; Cyclic GMP; Cycloheximide; Fibroblasts; Kinetics; Leucine; Mice; Microtubules; Prostaglandin Antagonists; Prostaglandins; Stimulation, Chemical; Theophylline; Uridine; Vinblastine | 1973 |
A study of the bioloical activity and resistance to phosphodiesterase of some derivatives and analogues of cyclic AMP.
Topics: Alkylation; Animals; Biological Assay; Brain; Cyclic AMP; Cyclic GMP; Female; Growth Hormone; Kinetics; Male; Phosphoric Diester Hydrolases; Pituitary Gland; Rats; Sex Factors; Structure-Activity Relationship; Theophylline; Thyrotropin; Time Factors | 1972 |
Regulation of levels of guanosine cyclic 3',5'-monophosphate in the central nervous system: effects of depolarizing agents.
Topics: Adenosine; Animals; Central Nervous System; Cerebellum; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Mice; Mice, Inbred Strains; Neuromuscular Depolarizing Agents; Ouabain; Potassium; Synaptic Transmission; Theophylline; Time Factors; Veratrine | 1973 |
Cyclic AMP and cyclic GMP enhance growth of chick embryo fibroblasts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bucladesine; Cell Division; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Fibroblasts; Inosine Nucleotides; Kinetics; Nucleotides, Cyclic; Theophylline; Tritium; Xanthines | 1973 |
Adenosine cyclic 3':5'-monophosphate-mediated transport of neutral and dibasic amino acids in jejunal mucosa.
Topics: Amino Acids; Animals; Biological Transport, Active; Bucladesine; Carbon Radioisotopes; Cholera; Cyclic AMP; Cyclic GMP; Female; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Jejunum; Leucine; Lysine; Rats; Structure-Activity Relationship; Theophylline; Toxins, Biological; Tritium | 1973 |
Mechanisms of lysosomal enzyme release from human leukocytes: microtubule assembly and membrane fusion induced by a component of complement.
Topics: Chemotaxis; Chromatography, Gel; Colchicine; Complement System Proteins; Cyclic AMP; Cyclic GMP; Cytochalasin B; Depression, Chemical; Enzymes; Glucuronidase; Histocytochemistry; Humans; Kinetics; L-Lactate Dehydrogenase; Leukocytes; Lysosomes; Microtubules; Peroxidases; Prostaglandins; Stimulation, Chemical; Theophylline; Zymosan | 1973 |
Interaction of various stimulators and inhibitors on insulin secretion in vitro.
Topics: Animals; Bucladesine; Cyclic GMP; Diazoxide; Drug Interactions; Epinephrine; Inosine Nucleotides; Insulin; Insulin Antagonists; Insulin Secretion; Male; Nucleotides, Cyclic; Pancreas; Rats; Starvation; Stimulation, Chemical; Theophylline; Thymine Nucleotides; Time Factors; Tolbutamide | 1973 |
Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspergillus; Bucladesine; Cell Aggregation; Cell Division; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Guanosine; Theophylline | 1973 |
Connective tissue activation. VI. The effects of cylic nucleotides on human synovial cells in vitro.
Topics: Adenosine Monophosphate; Bucladesine; Butyrates; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cycloheximide; Depression, Chemical; Drug Synergism; Fibroblasts; Glucose; Glycolysis; Humans; Hyaluronic Acid; Hydrocortisone; Lactates; Nucleotides, Cyclic; Peptides; Stimulation, Chemical; Synovial Membrane; Theophylline | 1974 |
Cyclic nucleotides as intracellular mediators of the expression of antigen-sensitive cells.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antibody Formation; Antibody-Producing Cells; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Depression, Chemical; Erythrocytes; Hemolytic Plaque Technique; Immunity, Cellular; Kinetics; Mice; Papaverine; Sheep; Spleen; Theophylline | 1973 |
Characteristics of cyclic 3',5'-nucleotide phosphodiesterase from the brain of the Madagascar cockroach (Gromphadorhina portentosa).
Topics: Adenosine Triphosphate; Animals; Brain; Caffeine; Cations, Divalent; Citrates; Cockroaches; Colorimetry; Cyclic AMP; Cyclic GMP; Diphosphates; Drug Stability; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Magnesium; Organ Specificity; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridines; Reserpine; Temperature; Theophylline; Time Factors; Tritium; Xanthines | 1974 |
Effects of bradykinin and indomethacin on cyclic GMP and cyclic AMP in lung slices.
Topics: Acetylcholine; Angiotensin II; Animals; Aspirin; Bradykinin; Culture Techniques; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; Indomethacin; Isoproterenol; Lung; Peptides; Promethazine; Stimulation, Chemical; Theophylline | 1973 |
Vascular and metabolic effects of theophylline, dibuturyl cyclic AMP and dibuturyl cyclic GMP in canine subcutaneous adipose tissue in situ.
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Edetic Acid; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Lactates; Lipid Metabolism; Norepinephrine; Perfusion; Pyruvates; Regional Blood Flow; Stimulation, Chemical; Theophylline; Time Factors; Vascular Resistance | 1974 |
Leukocytes as secretory organs of inflammation.
Topics: Atropine; Blood Platelets; Bucladesine; Carbachol; Cell Survival; Cells, Cultured; Colchicine; Cyclic AMP; Cyclic GMP; Deuterium; Epinephrine; Glucuronidase; Histamine; Humans; Inflammation; Isoproterenol; Leukocytes; Lymphocytes; Monocytes; Peroxidases; Phenylephrine; Prostaglandins; Theophylline | 1973 |
Cartilage cyclic nucleotide phosphodiesterase: inhibition by anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Bucladesine; Cartilage; Cartilage, Articular; Chickens; Cyclic AMP; Cyclic GMP; Dopamine; Epinephrine; Epiphyses; Gold; Indomethacin; Kinetics; Mefenamic Acid; Oxyphenbutazone; Papaverine; Phenylbutazone; Phosphodiesterase Inhibitors; Quinolines; Structure-Activity Relationship; Sulfinpyrazone; Theophylline; Tritium | 1974 |
Elevation of hepatic phenylalanine: pyruvate aminotransferase by dibutyryl cyclic AMP in rats.
Topics: Animals; Brain; Bucladesine; Cyclic AMP; Cyclic GMP; Dactinomycin; Glucagon; Inosine Nucleotides; Kidney; Liver; Male; Muscles; Myocardium; Nucleotides, Cyclic; Organ Specificity; Phenylalanine; Pyruvates; Rats; Spectrophotometry; Theophylline; Time Factors; Transaminases | 1974 |
Heat treatment of rat liver denosine 3':5'-monophosphate phosphodiesterase. Kinetic characterization of the low affinity enzyme.
Topics: Animals; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Drug Stability; Enzyme Activation; Female; Hot Temperature; Imidazoles; Kinetics; Liver; Phosphoric Diester Hydrolases; Protein Binding; Rats; Sodium Dodecyl Sulfate; Theophylline; Time Factors; Tritium | 1974 |
Analogs of alpha-tocopherol as inhibitors of cyclic-AMP and cyclic-GMP phosphodiesterases and effects of alpha-tocopherol deficiency on cyclic AMP-controlled metabolism.
Topics: Animals; Body Weight; Cattle; Cyclic AMP; Cyclic GMP; Glycogen; Kinetics; L-Serine Dehydratase; Liver; Male; Organ Size; Phosphodiesterase Inhibitors; Rats; Structure-Activity Relationship; Theophylline; Vitamin E; Vitamin E Deficiency | 1974 |
Elevation of cyclic GMP levels in central nervous system by excitatory and inhibitory amino acids.
Topics: Aminobutyrates; Animals; Calcium; Cerebellum; Cyclic AMP; Cyclic GMP; Depression, Chemical; Glutamates; Glycine; In Vitro Techniques; Mice; Potassium; Radioimmunoassay; Sodium Chloride; Stimulation, Chemical; Theophylline | 1974 |
Cyclic nucleotide levels in incubations of guinea pig trachea.
Topics: Acetylcholine; Adrenocorticotropic Hormone; Angiotensin II; Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Epinephrine; Glucagon; Histamine; Iodine Radioisotopes; Muscle, Smooth; Phenoxybenzamine; Phenylephrine; Propranolol; Prostaglandins; Radioimmunoassay; Serotonin; Theophylline; Trachea; Tritium | 1974 |
Modulation by cyclic AMP in vitro of liver plasma membrane (Na+--K+)-ATPase and protein kinases.
Topics: Adenosine Triphosphatases; Animals; Bucladesine; Butyrates; Caffeine; Cell Membrane; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Cytosol; Epinephrine; Kinetics; Liver; Magnesium; Male; Nucleotides, Cyclic; Potassium; Propranolol; Protein Kinases; Sodium; Theophylline | 1974 |
Cyclic nucleotide phosphodiesterase of Chlamydomonas reinhardtii.
Topics: Aminophylline; Bucladesine; Caffeine; Cations, Divalent; Chlamydomonas; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Diphosphates; Drug Stability; Edetic Acid; Enzyme Activation; Hydrogen-Ion Concentration; Inosine Nucleotides; Kinetics; Nucleotides, Cyclic; Phosphates; Phosphoric Diester Hydrolases; Sulfhydryl Reagents; Temperature; Theophylline; Thymine Nucleotides; Time Factors; Tritium; Uracil Nucleotides | 1974 |
Inhibition of 2-deoxy-D-glucose transport by theophylline, caffeine and papaverine in alveolar macrophages.
Topics: Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Kinetics; Macrophages; Papaverine; Prostaglandins; Pulmonary Alveoli; Sucrose; Theophylline; Tritium | 1974 |
Chemotactic responses of human polymorphonuclear leukocytes to cyclic GMP and other compounds.
Topics: Adenosine Monophosphate; Adult; Bucladesine; Cells, Cultured; Chemotaxis; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Humans; Kaolin; Neutrophils; Theophylline; Uric Acid | 1974 |
Inhibition of leukocyte migration by human tumors. Effect on patient survival.
Topics: Breast Neoplasms; Bucladesine; Cell Migration Inhibition; Colonic Neoplasms; Culture Media; Culture Techniques; Cyclic AMP; Cyclic GMP; Drug Synergism; Humans; Leukocytes; Lung Neoplasms; Neoplasms; Proteins; Theophylline; Tuberculin Test | 1974 |
A new assay of cyclic nucleotide phosphodiesterase; its application to human serum.
Topics: Adult; Animals; Brain; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Glioblastoma; Humans; Hydrogen-Ion Concentration; Kinetics; Magnesium; Male; Methods; Middle Aged; Parkinson Disease; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rabbits; Rats; Resins, Plant; Snakes; Temperature; Theophylline; Time Factors; Tritium; Venoms | 1974 |
Cyclic nucleotide levels during spontaneous uterine contractions.
Topics: Animals; Cyclic AMP; Cyclic GMP; Estrogens; Female; Isoproterenol; Muscle Contraction; Muscle, Smooth; Rats; Theophylline; Time Factors; Uterus | 1974 |
Regulation of hormone stimulation of adipose tissue lipolysis by guanosine triphosphate.
Topics: Adenosine Triphosphate; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Epididymis; Fatty Acids, Nonesterified; Glucagon; Guanine Nucleotides; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Lipid Mobilization; Male; Norepinephrine; Prostaglandins; Rats; Spectrometry, Fluorescence; Theophylline; Thymine Nucleotides; Time Factors; Uracil Nucleotides | 1974 |
Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic-AMP and cyclic-GMP.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Cattle; Cyclic AMP; Cyclic GMP; Dark Adaptation; Enzyme Activation; Freezing; Hot Temperature; Hydrolysis; In Vitro Techniques; Light; Magnesium; Manganese; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Photoreceptor Cells; Surface-Active Agents; Theophylline; Ultrasonics | 1974 |
The calcium ionophore A 23 187 as a probe for studying the role of Ca2+ ions in the mediation of carbachol effects on rat salivary glands: protein secretion and metabolism of phospholipids and glycogen.
Topics: Animals; Anti-Bacterial Agents; Bucladesine; Calcium; Carbachol; Carbon Radioisotopes; Carboxylic Acids; Cyclic GMP; Glucose; Glycogen; Kinetics; Leucine; Male; Parotid Gland; Phosphates; Phospholipids; Phosphoproteins; Phosphorus Radioisotopes; Protein Biosynthesis; Proteins; Rats; Submandibular Gland; Theophylline; Time Factors | 1974 |
Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin.
Topics: Animals; Autoradiography; Blood Proteins; Bucladesine; Carboxy-Lyases; Cell Line; Cricetinae; Cyclic GMP; Dactinomycin; DNA; Enzyme Induction; Fibroblasts; Insulin; Kidney; Mice; Nucleotides, Cyclic; Ornithine; Prostaglandins; Stimulation, Chemical; Theophylline; Thymidine; Time Factors; Tritium | 1974 |
The adhesion of BHK and PyBHK cells to the substratum.
Topics: Animals; Cell Adhesion; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Chelating Agents; Colchicine; Cricetinae; Cyclic AMP; Cyclic GMP; Cytochalasin B; Dexamethasone; Ethylene Glycols; Kidney; Microscopy, Phase-Contrast; Microtubules; Polyomavirus; Theophylline | 1974 |
The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.
Topics: Adenine; Adenosine; Animals; Bucladesine; Caffeine; Cell Aggregation; Colchicine; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Leukocytes; Nucleotides, Cyclic; Rabbits; Stimulation, Chemical; Theobromine; Theophylline; Vinblastine; Xanthines | 1974 |
Cyclic nucleotide phosphodiesterase in silkworm: purification and properties.
Topics: Animals; Bombyx; Caffeine; Cations, Divalent; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Edetic Acid; Electrophoresis, Disc; Fluorides; Hydrogen-Ion Concentration; Hydroxyapatites; Imidazoles; Kinetics; Larva; Molecular Weight; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Theophylline | 1974 |
Enhancement of the radioprotective effects of 2-mercaptoethylamine on colony-forming cells by agents which alter cyclic nucleotide levels.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Clone Cells; Cyclic AMP; Cyclic GMP; Drug Synergism; Female; Imidazoles; In Vitro Techniques; Isoproterenol; Mercaptoethylamines; Mice; Prostaglandins; Radiation Effects; Radiation-Protective Agents; Theophylline | 1974 |
In vitro response of goldfish (Carassius auratus L.) dermal melanophores to cyclic 3',5'-nucleotides, nucleoside 5'-phosphates and methylxanthines.
Topics: Adenosine Monophosphate; Animals; Binding, Competitive; Bucladesine; Caffeine; Chromatophores; Cyclic AMP; Cyclic GMP; Cyprinidae; Cytosine Nucleotides; Goldfish; Guanine Nucleotides; Melanophores; Nucleotides; Nucleotides, Cyclic; Skin; Theophylline; Thymine Nucleotides; Time Factors; Uracil Nucleotides | 1974 |
Modification of the lymphocyte response to mitogens by cyclic AMP and GMP.
Topics: Animals; B-Lymphocytes; Bucladesine; Cell Survival; Concanavalin A; Culture Media; Cyclic GMP; Depression, Chemical; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Lectins; Leucine; Lymphocytes; Mice; Mice, Inbred BALB C; Mitogens; Protein Biosynthesis; RNA; Spleen; Stimulation, Chemical; T-Lymphocytes; Theophylline; Thymidine; Tritium; Uridine | 1974 |
Rat diaphragm cyclic nucleotide-phosphodiesterase: influence of drugs affecting skeletal muscle contractility.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Dialysis; Diaphragm; Hydrochlorothiazide; Hydrogen-Ion Concentration; In Vitro Techniques; Inosine Nucleotides; Kinetics; Male; Muscle Contraction; Muscles; Nucleotides; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Theophylline; Tubocurarine; Uracil Nucleotides; Xanthines | 1974 |
[Existence of a protein kinase activity which maybe stimulated by 3',5'-cyclic adenosine monophosphate in adipose tissue of a teleostean fish, the trout (Salmo gairdnerii R.)].
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; Cyclic AMP; Cyclic GMP; Enzyme Activation; Isoenzymes; Kinetics; Protein Kinases; Proteins; Theophylline; Trout | 1974 |
Proceedings: Cyclic nucleotides and ethanol withdrawal head-twitches in mice.
Topics: Animals; Bucladesine; Cyclic GMP; Ethanol; Head; Humans; Imidazoles; Methyltyrosines; Mice; Mice, Inbred Strains; Movement; Nucleotides; Serotonin; Substance Withdrawal Syndrome; Theophylline; Time Factors | 1974 |
Changes in spleen weight, cyclic-AMP content, and serum-corticosterone levels of rats in response to CO2.
Topics: Adrenal Glands; Animals; Carbon Dioxide; Corticosterone; Cyclic AMP; Cyclic GMP; Denervation; Hypoxia; Male; Organ Size; Pentobarbital; Phentolamine; Propranolol; Rats; Spleen; Theophylline; Tritium | 1974 |
The mechanism of action of soluble lymphocytic mediators. II. Modification of macrophage migration and migration inhibitory factor action by drugs, enzymes and cationic environment.
Topics: Animals; Ascitic Fluid; Bucladesine; Calcium; Cations, Divalent; Cell Migration Inhibition; Clostridium perfringens; Cyclic AMP; Cyclic GMP; Guinea Pigs; Lipase; Macrophage Migration-Inhibitory Factors; Macrophages; Magnesium; Male; Neuraminidase; Phospholipases; Pronase; Prostaglandins; Protein Biosynthesis; RNA; Theophylline; Trypsin; Tuberculin | 1974 |
Dependence of pancreatic enzyme secretion on extracellular Ca++ and its modification by cyclic nucleotides and thyrocalcitonin.
Topics: Acetylcholine; Amylases; Animals; Bucladesine; Calcitonin; Calcium Chloride; Cats; Cholecystokinin; Cyclic AMP; Cyclic GMP; Pancreas; Pancreatic Juice; Proteins; Theophylline | 1974 |
Cyclic guanosine and adenosine 3',5'-monophosphates in canine thyroid: localization by immunofluorescence.
Topics: Acetylcholine; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Immunochemistry; In Vitro Techniques; Physostigmine; Theophylline; Thyroid Gland; Thyrotropin | 1974 |
Effects of loperamide on intestinal ion transport.
Topics: Animals; Calcimycin; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; Dinoprostone; Ileum; Intestinal Mucosa; Ion Channels; Loperamide; Male; Piperidines; Prostaglandins E; Rabbits; Sodium; Stimulation, Chemical; Theophylline; Water-Electrolyte Balance | 1984 |
Effect of gamma-aminobutyric acid on cyclic nucleotides content of guinea-pig cerebral cortex slices.
Topics: Adenosine; alpha-Methyltyrosine; Animals; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Methyltyrosines; Neurons; Norepinephrine; Phentolamine; Picrotoxin; Reserpine; Theophylline | 1984 |
Aminophylline potentiates sodium nitroprusside-induced hypotension in the dog.
Topics: Aminophylline; Animals; Blood Pressure; Cyclic GMP; Dogs; Drug Synergism; Ferricyanides; Heart Rate; Nitroprusside; Stroke Volume; Theophylline; Vascular Resistance | 1984 |
Patterns of cyclic nucleotides in normal and leukaemic human leucocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Carbachol; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Isoproterenol; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Serotonin; Theophylline | 1980 |
The involvement of cyclic GMP in tyrosine aminotransferase degradation in rat hepatoma tissue culture cells.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Liver Neoplasms, Experimental; Manganese; Phosphodiesterase Inhibitors; Rats; Theophylline; Time Factors; Tyrosine Transaminase | 1981 |
Plasma concentrations of the cyclic nucleotides, adenosine 3',5'-monophosphate and guanosine 3'.5'-monophosphate, in healthy adults treated with theophylline.
Topics: Adrenergic beta-Agonists; Adult; Cyclic AMP; Cyclic GMP; Female; Humans; Male; Middle Aged; Theophylline | 1982 |
Inverse correlation between cyclic GMP and tyrosine aminotransferase degradation in rat hepatoma tissue culture cells.
Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Insulin; Liver Neoplasms, Experimental; Rats; Theophylline; Tyrosine Transaminase | 1982 |
Possible involvement of cGMP in the control of tyrosine aminotransferase degradation in rat hepatocytes.
Topics: Animals; Cyclic GMP; Liver; Male; Manganese; Nucleotides, Cyclic; Rats; Theophylline; Tyrosine Transaminase | 1983 |
Influence of isoproterenol and methylisobutylxanthine on the contractile and cyclic nucleotide effects of methacholine in isolated rat atria.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Interactions; Female; Heart Atria; In Vitro Techniques; Isoproterenol; Methacholine Compounds; Myocardial Contraction; Ouabain; Rats; Stimulation, Chemical; Theophylline | 1980 |
Effects of isoprenaline and 1-methyl-3-isobutylxanthine on cyclic nucleotides and cyclic AMP-dependent protein kinase in rabbit colon smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colon; Cyclic AMP; Cyclic GMP; Isoproterenol; Muscle, Smooth; Protein Kinases; Rabbits; Sodium Fluoride; Theophylline | 1980 |
Activation of human lymphocyte high affinity cyclic AMP phosphodiesterase by culture with 1-methyl-3-isobutylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adult; Azides; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Humans; Kinetics; Lymphocytes; Theophylline | 1980 |
Enhancement by 3-isobutyl-1-methylxanthine and cholera toxin of 12-O-tetradecanoylphorbol-13-acetate-stimulated cyclic nucleotide levels and ornithine decarboxylase activity in isolated epidermal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carboxy-Lyases; Cell Separation; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cyclic GMP; Epidermis; Mice; Nucleotides, Cyclic; Ornithine Decarboxylase; Phorbols; Tetradecanoylphorbol Acetate; Theophylline; Time Factors | 1980 |
Role of Ca2+ and cyclic nucleotides in the control of prostaglandin E production in the rat anterior pituitary gland.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acids; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Growth Hormone; In Vitro Techniques; Male; Pituitary Gland, Anterior; Potassium; Prostaglandins E; Rats; Theophylline | 1980 |
Stimulus-secretion coupling in rat pancreas: role of sodium, calcium and cyclic nucleotides studied by X-537A and BrX-537A.
Topics: Amylases; Animals; Atropine; Biological Transport; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Ionophores; Lasalocid; Male; Ouabain; Pancreas; Rats; Secretory Rate; Theophylline | 1980 |
Inhibition by purine compounds of cyclic GMP-stimulated cyclic AMP phosphodiesterase activity from a particulate fraction of rat striatum.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Hypoxanthines; Inosine; Male; Purines; Rats; Theophylline | 1980 |
Effects of cyclic AMP- and cyclic GMP- phosphodiesterase inhibitors on immunological release of histamine and on lung contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aza Compounds; Cromolyn Sodium; Cyclic AMP; Cyclic GMP; Cyclopentanes; Histamine Release; Humans; In Vitro Techniques; Lung; Male; Papaverine; Purinones; Pyrrolidinones; Rats; Rolipram; Theophylline | 1981 |
Evidence against a role of cyclic nucleotides in the regulation of anaphylactic histamine release in isolated rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aza Compounds; Cyclic AMP; Cyclic GMP; Histamine Release; Male; Mast Cells; Purinones; Rats; Rats, Inbred Strains; Theophylline | 1981 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carboxy-Lyases; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Mice; Ornithine Decarboxylase; Phorbols; Skin; Tetradecanoylphorbol Acetate; Theophylline; Time Factors | 1981 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1981 |
Control of pancreatic cyclic nucleotide levels and amylase secretion by noncholinergic, nonadrenergic nerves. A study employing electrical field stimulation of guinea pig segments.
Topics: Acetylcholine; Amylases; Animals; Ceruletide; Cyclic AMP; Cyclic GMP; Electric Stimulation; Epinephrine; Guinea Pigs; Kinetics; Pancreas; Potassium; Theophylline; Vasoactive Intestinal Peptide | 1981 |
Paradoxical stimulation by 1-methyl-3-isobutylxanthine of rat liver cyclic AMP phosphodiesterase activity.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Liver; Rats; Theophylline | 1982 |
On the mechanism by which theophylline inhibits histamine release from rat mast cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Antigens; Cyclic AMP; Cyclic GMP; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Species Specificity; Theophylline | 1982 |
The effect of isobutylmethylxanthine on the photoresponse and phosphorylation of phosphatidylinositol in octopus retina.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Calcium; Cyclic GMP; Darkness; Kinetics; Light; Octopodiformes; Phosphatidylinositols; Phosphorylation; Photic Stimulation; Photoreceptor Cells; Retina; Theophylline | 1983 |
Cyclic GMP efflux from liver slices.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cyclic GMP; In Vitro Techniques; Iodoacetamide; Kinetics; Liver; Male; Methylnitronitrosoguanidine; Probenecid; Rats; Rats, Inbred Strains; Theophylline | 1983 |
Regulation of abalone sperm cyclic AMP concentrations and the acrosome reaction by calcium and methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; Acrosome; Animals; Calcium; Cyclic GMP; Male; Mollusca; Sea Urchins; Spermatozoa; Theophylline; Xanthines | 1983 |
Cyclic nucleotide responses and radiation-induced mitotic delay in Physarum polycephalum.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Caffeine; Cobalt Radioisotopes; Cyclic AMP; Cyclic GMP; Gamma Rays; Mitosis; Phosphodiesterase Inhibitors; Physarum; Theophylline; Time Factors | 1984 |
Relationship between cycles in level of serotonin N-acetyltransferase activity and cyclic GMP content of cultured chick pineal glands.
Topics: 1-Methyl-3-isobutylxanthine; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Calcium Chloride; Chickens; Circadian Rhythm; Cyclic GMP; Darkness; Egtazic Acid; Etazolate; Folic Acid; Hypoxanthine; Hypoxanthines; Light; Pineal Gland; Theophylline | 1984 |
Adenosine and adenosine analogues stimulate adenosine cyclic 3', 5'-monophosphate-dependent chloride secretion in the mammalian ileum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Chlorides; Cyclic AMP; Cyclic GMP; Ileum; Kinetics; Male; Phenylisopropyladenosine; Rabbits; Theophylline | 1984 |
Alteration of cyclic nucleotide levels in phorbol 12-myristate 13-acetate treated myoblasts.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminophylline; Animals; Biological Transport, Active; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Deoxyglucose; Kinetics; Muscles; Phorbols; Tetradecanoylphorbol Acetate; Theophylline | 1980 |
Diurnal cycles in serotonin acetyltransferase activity and cyclic GMP content of cultured chick pineal glands.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Biological Clocks; Chickens; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Light; Male; Organ Culture Techniques; Pineal Gland; Theophylline | 1980 |
The time course of changes in cyclic nucleotide levels during cholinergic inhibition of positive inotropic actions of isoprenaline and theophylline in the isolated canine ventricular myocardium.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Cyclic GMP; Dogs; Drug Interactions; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Pindolol; Stimulation, Chemical; Theophylline; Time Factors; Ventricular Function | 1980 |
Evidence against the involvement of cyclic GMP in the insulin-stimulation of lipoprotein lipase activity in fat cells.
Topics: Adipose Tissue; Animals; Cyclic GMP; In Vitro Techniques; Insulin; Lipoprotein Lipase; Male; Rats; Theophylline | 1980 |
Comparison of the effects of theophylline, prednisolone and sleep withdrawal on airway obstruction and urinary cyclic AMP/cyclic GMP excretion of asthmatic children with and without nocturnal asthma.
Topics: Adolescent; Airway Obstruction; Asthma; Child; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Female; Humans; Male; Maximal Expiratory Flow Rate; Prednisolone; Sleep; Theophylline | 1980 |
Effect of phosphodiesterase inhibitors on heart contractile behaviour, protein kinase activity and cyclic nucleotide levels.
Topics: Animals; Cyclic AMP; Cyclic GMP; Myocardial Contraction; Myocardium; Nucleotides, Cyclic; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Theophylline | 1980 |
A role of guanosine 3',5'-monophosphate in human-prolactin-induced estrogen production by feminizing adrenal neoplastic cells.
Topics: Adrenal Gland Neoplasms; Cell Line; Cyclic AMP; Cyclic GMP; Estrogens; Hormones, Ectopic; Humans; Prolactin; Theophylline | 1980 |
The involvement of cAMP in lymphocyte capping.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Bucladesine; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Immunologic Capping; Lymphoma; Membrane Proteins; Mice; Rabbits; Rats; Theophylline; Thymoma | 1981 |
Interaction of calcium and cyclic nucleotides in thyroliberin-stimulated prolactin release.
Topics: Animals; Calcium; Cells, Cultured; Cobalt; Cyclic AMP; Cyclic GMP; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Theophylline; Thyrotropin-Releasing Hormone | 1981 |
Effect of theophylline and imidazole on cyclic AMP and cyclic GMP levels in active sartorius muscle of Rana esculenta.
Topics: Animals; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscles; Rana esculenta; Theophylline | 1981 |
Theophylline reduces poly (ADP-ribose) synthetase from chick embryo liver nuclei.
Topics: Animals; Cell Nucleus; Chick Embryo; Cyclic AMP; Cyclic GMP; Liver; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Theophylline | 1981 |
The relationship between variations in levels of serotonin acetyltransferase activity and cGMP content in cultured chick pineal glands.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Chickens; Circadian Rhythm; Cyclic GMP; Light; Organ Culture Techniques; Periodicity; Pineal Gland; Theophylline | 1981 |
Effects of cyclic nucleotides on growth activity of V79-1A cells.
Topics: Animals; Bucladesine; Cell Division; Cell Line; Cricetinae; Cricetulus; Cyclic AMP; Cyclic CMP; Cyclic GMP; Drug Synergism; Nucleotides, Cyclic; Theophylline | 1981 |
Changes in cyclic AMP and cyclic GMP concentrations during the action of 5-hydroxytryptamine on an insect salivary gland.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cyclic AMP; Cyclic GMP; Diptera; Female; Heterocyclic Compounds; Imines; In Vitro Techniques; Kinetics; Male; Salivary Glands; Serotonin; Theophylline | 1980 |
Adenocarcinoma of the human exocrine pancreas: presence of secretin and caerulein receptors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenocarcinoma; Animals; Ceruletide; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Mice; Pancreatic Neoplasms; Receptors, Cell Surface; Receptors, Cholecystokinin; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Secretin; Theophylline | 1981 |
Effect of Escherichia coli heat-stable enterotoxin, cholera toxin and theophylline on ion transport in porcine colon.
Topics: Animals; Biological Transport; Cholera Toxin; Colon; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enterotoxins; Escherichia coli; Intestinal Mucosa; Ions; Membrane Potentials; Swine; Theophylline | 1981 |
Evidence that cyclic GMP may regulate cyclic AMP metabolism in the isolated frog ventricle.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Myocardial Contraction; Myocardium; Rana temporaria; Receptors, Muscarinic; Theophylline | 1981 |
[Effect of theophylline on the electrical activity of the Helix pomatia neuron PPa2].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic AMP; Cyclic GMP; Electrophysiology; Ganglia; Helix, Snails; Ion Channels; Neurons; Theophylline | 1981 |
A study of the mechanism of estrogen as an antiatherosclerotic: the inhibitory effect of estrogen on A23187-induced contraction of the aortic wall.
Topics: Animals; Anti-Bacterial Agents; Aorta; Bucladesine; Calcimycin; Cyclic AMP; Cyclic GMP; Estradiol; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Theophylline | 1982 |
Effects of cyclic adenosine and cyclic guanosine nucleotides and theophylline on gastrin synthesis and secretion in rat antral organ culture.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrins; Male; Organ Culture Techniques; Pyloric Antrum; Rats; Rats, Inbred Strains; Theophylline | 1982 |
Pharmacological investigations on electrically-induced changes of cyclic nucleotides in guinea-pig brain slices.
Topics: Acetylcholine; Adenosine; Animals; Brain; Cyclic AMP; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Norepinephrine; Potassium Chloride; Tetrodotoxin; Theophylline | 1982 |
[Effect of inflammation mediators and antirheumatic drugs on the production of superoxide anion (O2-) by polymorphonuclear cells in normals and rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclic AMP; Cyclic GMP; Humans; Neutrophils; Oxygen; Prostaglandins E; Superoxides; Theophylline | 1982 |
Effects of cyclic nucleotides on the shedding of tumor cell surface membranes.
Topics: Animals; Bucladesine; Cell Line; Cell Membrane; Cyclic AMP; Cyclic GMP; Guanosine Triphosphate; Mast-Cell Sarcoma; Microscopy, Electron, Scanning; Neoplasms, Experimental; Surface Properties; Theophylline | 1982 |
Epinephrine-induced changes in the cyclic nucleotide content of fish melanoma cells.
Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic GMP; Epinephrine; Fishes; Melanocytes; Melanoma; Melanophores; Pigments, Biological; Theophylline | 1982 |
[The renaissance of theophylline therapy].
Topics: Calcium; Cyclic AMP; Cyclic GMP; Delayed-Action Preparations; Humans; Lung Diseases, Obstructive; Mast Cells; Prostaglandins E; Receptors, Histamine; Theophylline | 1982 |
Phosphodiesterase activity of the lower urinary tract.
Topics: Animals; Calmodulin; Cyclic AMP; Cyclic GMP; Dogs; Male; Muscle, Smooth; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rabbits; Theophylline; Urogenital System | 1982 |
Effects of prostaglandins on cyclic nucleotide phosphodiesterase activity in the human term placenta.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Epinephrine; Epoprostenol; Female; Humans; Kinetics; Placenta; Pregnancy; Prostaglandins; Prostaglandins E; Theophylline; Time Factors | 1982 |
[Effects of colchicine, cyclic nucleotides and biogenic amines on the chemoreceptor apparatus of the tongue].
Topics: Adenosine Monophosphate; Animals; Bucladesine; Colchicine; Cyclic AMP; Cyclic GMP; Epinephrine; Evoked Potentials; Guanosine Monophosphate; Nucleotides, Cyclic; Rana temporaria; Serotonin; Stimulation, Chemical; Taste Buds; Theophylline | 1983 |
Cyclic nucleotides and calcium: their role in the control of cell communication in the heart.
Topics: Animals; Bucladesine; Calcium; Cell Communication; Cyclic AMP; Cyclic GMP; Electric Conductivity; Intercellular Junctions; Membrane Potentials; Myocardium; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Theophylline | 1983 |
Action of adenosine on cyclic 3',5'-nucleotides in glomeruli.
Topics: Adenosine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Kinetics; Rats; Serotonin; Theophylline | 1983 |
Bicarbonate transport across the frog choroid plexus and its control by cyclic nucleotides.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicarbonates; Biological Transport, Active; Cholera Toxin; Choroid Plexus; Colforsin; Cyclic AMP; Cyclic GMP; Diterpenes; Hormones; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Nucleotides, Cyclic; Rana catesbeiana; Theophylline | 1983 |
Pathophysiologic features of swine dysentery: cyclic nucleotide-independent production of diarrhea.
Topics: Animals; Biological Transport, Active; Colon; Cyclic AMP; Cyclic GMP; Dysentery; Electrolytes; Intestinal Absorption; Intestinal Mucosa; Swine; Swine Diseases; Theophylline; Treponemal Infections; Water | 1983 |
Differing effects of cGMP and cAMP on ion transport across flounder intestine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bumetanide; Chlorides; Cyclic AMP; Cyclic GMP; Fishes; Intestinal Absorption; Potassium; Rubidium; Sodium; Theophylline | 1984 |
Age-related differential suppression of mitogenic responsiveness in murine splenocytes exposed in vitro to theophylline.
Topics: Age Factors; Animals; Concanavalin A; Cyclic AMP; Cyclic GMP; Female; Immunosuppression Therapy; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Spleen; Theophylline | 1984 |
Methylxanthines and calcium-mobilizing agents inhibit the expression of cytokine-inducible nitric oxide synthase and vascular cell adhesion molecule-1 in murine microvascular endothelial cells.
Topics: Amino Acid Oxidoreductases; Animals; Atropine; Caffeine; Calcium; Carbachol; Cell Adhesion Molecules; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Gene Expression; Hydrogen-Ion Concentration; Interferon-gamma; Ionomycin; Mice; Nitric Oxide Synthase; Rats; Recombinant Proteins; RNA, Messenger; Signal Transduction; Terpenes; Thapsigargin; Theophylline; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Xanthines | 1994 |
IBMX induces calcium release from intracellular stores in rat sensory neurones.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Biological Transport; Bucladesine; Caffeine; Calcium; Cell Compartmentation; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Endoplasmic Reticulum; Ganglia, Spinal; Neurons, Afferent; Rats; Theophylline | 1995 |
Insulin increases cyclic nucleotide content in human vascular smooth muscle cells: a mechanism potentially involved in insulin-induced modulation of vascular tone.
Topics: Arterioles; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Iloprost; Insulin; Isoflavones; Kinetics; Muscle Tonus; Muscle, Smooth, Vascular; Protein-Tyrosine Kinases; Recombinant Proteins; Theophylline | 1995 |
Activation of p70 S6 kinase and erk-encoded mitogen-activated protein kinases is resistant to high cyclic nucleotide levels in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Kinetics; Mice; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Nicotinic Acids; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Phthalazines; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Theophylline | 1995 |
Atrial natriuretic factor (ANF) does not affect ion transport in human intestine but does in porcine intestine.
Topics: Adolescent; Aged; Animals; Atrial Natriuretic Factor; Autoradiography; Biological Transport; Chloride Channels; Colon; Cyclic GMP; Female; Humans; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Ion Channels; Membrane Proteins; Middle Aged; Receptors, Atrial Natriuretic Factor; Sodium Channels; Species Specificity; Swine; Theophylline | 1993 |
Muscarinic agonists have no measurable effect on cGMP formation of rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Bethanechol; Bethanechol Compounds; Calcium; Carbachol; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Kinetics; Male; Nitroprusside; Norepinephrine; Parasympathomimetics; Pineal Gland; Rats; Rats, Sprague-Dawley; Theophylline | 1993 |
Regulation of cAMP-activated apical membrane chloride conductance in gallbladder epithelium.
Topics: Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Electrophysiology; Enzyme Activation; Epithelium; Ethers, Cyclic; Gallbladder; In Vitro Techniques; Ionomycin; Membrane Potentials; Necturus; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Theophylline | 1994 |
Bicarbonate secretion in rabbit ileum: electrogenicity, ion dependence, and effects of cyclic nucleotides.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bicarbonates; Bumetanide; Chlorides; Cyclic GMP; Ethoxzolamide; Ileum; In Vitro Techniques; Male; Rabbits; Sodium; Theophylline | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents | 1993 |
Different effects of cGMP and cAMP in the intestine of the European eel, Anguilla anguilla.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Anguilla; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Biological Transport, Active; Chlorides; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electrophysiology; Epithelium; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Peptide Fragments; Potassium; Seawater; Sodium; Structure-Activity Relationship; Swine; Theophylline; Vasoactive Intestinal Peptide; Vasodilator Agents | 1996 |
Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations.
Topics: Adenosine Diphosphate; Adult; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Insulin; Male; Nitroglycerin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Theophylline; Vasodilator Agents | 1996 |
Simultaneous presence of cAMP and cGMP exert a co-ordinated inhibitory effect on the agonist-evoked Ca2+ signal in pancreatic acinar cells.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; Pancreas; Papaverine; Phosphoric Diester Hydrolases; Signal Transduction; Theophylline | 1996 |
Modulation of vasorelaxant responses to potassium channel openers by basal nitric oxide in the rat isolated superior mesenteric arterial bed.
Topics: Animals; Benzopyrans; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Guanidines; In Vitro Techniques; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Papaverine; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Stereoisomerism; Theophylline; Vasodilation; Vasodilator Agents | 1996 |
Role of nitric oxide, cyclic nucleotides, and the activation of ATP-sensitive K+ channels in the contribution of adenosine to hypoxia-induced pial artery dilation.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Arteries; Blood Pressure; Cyclic AMP; Cyclic GMP; Enkephalin, Leucine; Enkephalin, Methionine; Female; Glyburide; Hypoxia; Male; Nitric Oxide; Nucleotides, Cyclic; Pia Mater; Potassium Channels; Swine; Theophylline; Vasodilation; Vasodilator Agents | 1997 |
Role of cyclic nucleotides in contraction induced by oxytocin in the testicular capsule of the rat in vitro.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Male; omega-N-Methylarginine; Oxytocin; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Testis; Theophylline | 1996 |
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Coronary Circulation; Cyclic GMP; Cyclooxygenase Inhibitors; Electrocardiography; Endothelins; Epoprostenol; Guinea Pigs; Hyperemia; In Vitro Techniques; Indomethacin; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Prostaglandin Antagonists; Purinergic P1 Receptor Antagonists; Purines; Theophylline | 1996 |
Amrinone and theophylline differentially regulate cytokine and nitric oxide production in endotoxemic mice.
Topics: Amrinone; Animals; Cyclic AMP; Cyclic GMP; Cytokines; Endotoxemia; Interleukin-10; Interleukin-6; Lipopolysaccharides; Male; Mice; Nitric Oxide; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha | 1997 |
Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP.
Topics: Animals; Aorta; Bucladesine; Cattle; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Isosorbide; Kinetics; Male; Muscle, Smooth, Vascular; Nitroprusside; Penicillamine; Rats; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Theophylline; Thionucleotides; Transcription, Genetic; Vasodilator Agents | 1997 |
Defect of cold-sensitive response in calmodulin mutants of Paramecium and the restoration by cyclic nucleotide.
Topics: Animals; Calmodulin; Cell Movement; Cells, Cultured; Cold Temperature; Cyclic AMP; Cyclic GMP; Membrane Potentials; Mutation; Nucleotides, Cyclic; Paramecium tetraurelia; Patch-Clamp Techniques; Radioimmunoassay; Theophylline; Thermosensing | 1997 |
Cyclic AMP stimulates the cyclic GMP egression pump in human erythrocytes: effects of probenecid, verapamil, progesterone, theophylline, IBMX, forskolin, and cyclic AMP on cyclic GMP uptake and association to inside-out vesicles.
Topics: 1-Methyl-3-isobutylxanthine; Biological Transport, Active; Colforsin; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Erythrocyte Membrane; Humans; Ion Pumps; Probenecid; Progesterone; Theophylline; Verapamil | 1998 |
Effects of theophylline on lymphocyte phosphodiesterase activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Age Factors; Aminophylline; Asthma; Bronchodilator Agents; Cyclic AMP; Cyclic GMP; Female; Humans; Injections, Intravenous; Lymphocytes; Male; Middle Aged; Phosphodiesterase Inhibitors; Sex Factors; Terbutaline; Theophylline; Time Factors | 1998 |
Possible novel mechanism for bitter taste mediated through cGMP.
Topics: Aminoquinolines; Animals; Caffeine; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Glycine Agents; Methylene Blue; Mice; Nitro Compounds; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinoxalines; Signal Transduction; Strychnine; Sulfhydryl Reagents; Taste; Theophylline | 1999 |
Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Caffeine; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Gene Expression; Humans; Magnesium; Membrane Potentials; Nitroprusside; Patch-Clamp Techniques; Potassium Channels; Recombinant Proteins; Theophylline; Transfection; Xanthines | 2000 |
Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model.
Topics: Alkaloids; Animals; Animals, Newborn; Apoptosis; Astrocytes; Carbazoles; Cell Survival; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytochrome c Group; Dipyridamole; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Indoles; Mitochondria; Pentoxifylline; Peptide Hydrolases; Phosphodiesterase Inhibitors; Purinones; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Theophylline; Vinca Alkaloids | 2001 |
Relationship between bicarbonate and cyclic nucleotide in the promoting effects on head-to-head agglutination in boar spermatozoa.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Male; Papaverine; Purinergic P1 Receptor Antagonists; Sodium Bicarbonate; Sperm Agglutination; Sperm Head; Swine; Theophylline | 2002 |
Role of cyclic nucleotides in regulation of pulmonary artery tone in rabbits.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pulmonary Artery; Rabbits; Signal Transduction; Sympathomimetics; Theophylline; Vasodilator Agents | 2003 |
Protection by sildenafil and theophylline of lead acetate-induced oxidative stress in rat submandibular gland and saliva.
Topics: Animals; Cyclic AMP; Cyclic GMP; Infusions, Parenteral; Male; Organometallic Compounds; Oxidative Stress; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Saliva; Sildenafil Citrate; Submandibular Gland; Sulfones; Theophylline | 2003 |
Indirect phosphorylation-dependent modulation of postsynaptic nicotinic acetylcholine responses by 5-hydroxytryptamine.
Topics: Acetylcholine; Animals; Central Nervous System; Cockroaches; Cyclic AMP; Cyclic GMP; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Male; Membrane Potentials; Motor Neurons; Patch-Clamp Techniques; Phosphorylation; Receptors, Nicotinic; Serotonin; Staurosporine; Synaptic Transmission; Theophylline; Time Factors | 2005 |
Cyclic 3', 5' guanosine monophosphate and larval midgut ecdysone 20-monooxygenase activity of the tobacco hornworm, Manduca sexta.
Topics: Animal Structures; Animals; Aryl Hydrocarbon Hydroxylases; Cyclic GMP; Intestines; Larva; Manduca; Radioimmunoassay; Steroid Hydroxylases; Theophylline; Time Factors | 2010 |
Relative resistance to oral theophylline treatment in patients with hyposmia manifested by decreased secretion of nasal mucus cyclic nucleotides.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cyclic AMP; Cyclic GMP; Female; Humans; Male; Middle Aged; Mucus; Olfaction Disorders; Phosphodiesterase Inhibitors; Theophylline; Treatment Failure; Young Adult | 2011 |
Modulation of high affinity ATP-dependent cyclic nucleotide transporters by specific and non-specific cyclic nucleotide phosphodiesterase inhibitors.
Topics: ATP-Binding Cassette Transporters; Caffeine; Carbolines; Cyclic AMP; Cyclic GMP; Dipyridamole; Humans; Imidazoles; Kinetics; Multidrug Resistance-Associated Proteins; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purinones; Sulfones; Tadalafil; Theophylline; Triazines; Vardenafil Dihydrochloride | 2014 |
A modular chromosomally integrated toolkit for ectopic gene expression in Vibrio cholerae.
Topics: Bacterial Proteins; Cyclic GMP; Ectopic Gene Expression; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Promoter Regions, Genetic; Riboswitch; Theophylline; Vibrio cholerae | 2020 |
Theophylline-induced endothelium-dependent vasodilation is mediated by increased nitric oxide release and phosphodiesterase inhibition in rat aorta.
Topics: Animals; Aorta; Aorta, Thoracic; Calcium; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphoric Diester Hydrolases; Rats; Theophylline; Vasodilation | 2023 |