theophylline and chlorpropamide

theophylline has been researched along with chlorpropamide in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's0 (0.00)18.2507
2000's5 (15.63)29.6817
2010's10 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Handler, JS; Keiser, HR; Zusman, RM1
Jatlow, P1
Mendoza, SA1
Earley, LE1
Ando, A; Orita, Y; Shirai, D; Takamitsu, Y; Urakabe, S1
Shirai, D; Urakabe, S1
Goren, EN; Hirsch, AH; Rosen, OM1
Appel, GB; Franki, N; Gouaux, J; Hays, RM; Lozada, ES1
Lasseter, KC; Levey, GS; McCarthy, JS; Palmer, RF1
Ozer, A; Sharp, GW1
Brown, CF; Mendoza, SA1
Handler, JS; Omachi, RS; Orloff, J; Robbie, DE1
Ariëns, EJ1
Kasirsky, G; Lawless, GB1
Clark, BG; Vestal, RE1
Bradley, MP; Forrester, IT1
UESUGI, Y1

Reviews

2 review(s) available for theophylline and chlorpropamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Oral antidiabetics. Dose, plasma concentration and effect].
    Acta diabetologica latina, 1969, Volume: 6 Suppl 1

    Topics: Acetohexamide; Adrenergic beta-Antagonists; Animals; Blood Glucose; Carbutamide; Chemical Phenomena; Chemistry; Chlorpropamide; Cyclic AMP; Diazoxide; Drug Antagonism; Drug Synergism; Glucagon; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Isoproterenol; Kidney; Liver; Sulfonamides; Sulfonylurea Compounds; Theophylline; Tolbutamide

1969

Other Studies

30 other study(ies) available for theophylline and chlorpropamide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Inhibition of vasopressin-stimulated prostaglandin E biosynthesis by chlorpropamide in the toad urinary bladder. Mechanism of enhancement of vasopressin-stimulated water flow.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:6

    Topics: Animals; Anura; Arginine Vasopressin; Chlorpropamide; Chromatography, Thin Layer; Cyclic AMP; Glyburide; Lipid Metabolism; Permeability; Prostaglandins E; Stimulation, Chemical; Structure-Activity Relationship; Theophylline; Tolbutamide; Urinary Bladder; Vasopressins; Water

1977
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences.
    American journal of clinical pathology, 1973, Volume: 59, Issue:2

    Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin

1973
Effect of chlorpropamide on the permeability of the urinary bladder of the toad and the response to vasopressin, adenosine-3',5'-monophosphate and theophylline.
    Endocrinology, 1969, Volume: 84, Issue:2

    Topics: Adenine Nucleotides; Animals; Anura; Cell Membrane Permeability; Chlorpropamide; Cyclic AMP; In Vitro Techniques; Osmosis; Stimulation, Chemical; Theophylline; Urinary Bladder; Vasopressins; Water

1969
Chlorpropamide antidiuresis.
    The New England journal of medicine, 1971, Jan-14, Volume: 284, Issue:2

    Topics: Aged; Animals; Cell Membrane Permeability; Chlorpropamide; Cyclic AMP; Diabetes Insipidus; Diabetes Mellitus; Diuresis; Drug Synergism; Humans; Rats; Theophylline; Vasopressins

1971
Effect of sulfonylureas on the permeability to water and electrical properties of the urinary bladder of the toad.
    Japanese circulation journal, 1970, Volume: 34, Issue:7

    Topics: Acetohexamide; Animals; Anura; Biguanides; Biological Transport; Calcium; Carbutamide; Cell Membrane Permeability; Chlorpropamide; Cyclic AMP; Depression, Chemical; Dinitrophenols; Electrophysiology; Epinephrine; Glutathione; Pyrimidines; Stimulation, Chemical; Sulfonic Acids; Temperature; Theophylline; Tolbutamide; Urinary Bladder; Vasopressins; Water

1970
[Action mechanism of vasopressin on biological membranes and its inhibition].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:4

    Topics: Adenine Nucleotides; Animals; Anura; Calcium; Catecholamines; Cell Membrane Permeability; Chlorpropamide; Cyclic AMP; Glutathione; In Vitro Techniques; Magnesium; Membrane Potentials; Mucous Membrane; Theophylline; Urinary Bladder; Vasopressins; Water

1971
Factors which influence cyclic AMP formation and degradation in an islet cell tumor of the Syrian hamster.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:2

    Topics: Adenoma, Islet Cell; Adenylyl Cyclases; Animals; Chlorpropamide; Chromatography, Paper; Cricetinae; Cyclic AMP; Glucagon; Insulin; Insulin Secretion; Male; Neoplasm Transplantation; Neoplasms, Experimental; Phosphoric Monoester Hydrolases; Stimulation, Chemical; Theophylline

1971
Studies of the mode of action of the sulfonylureas and phenylacetamides in enhancing the effect of vasopressin.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:4

    Topics: Acetaminophen; Adenylyl Cyclase Inhibitors; Animals; Bufo marinus; Chlorpropamide; Cyclic AMP; Drug Synergism; In Vitro Techniques; Osmosis; Phenacetin; Phosphoric Monoester Hydrolases; Prostaglandins; Stimulation, Chemical; Sulfonylurea Compounds; Theophylline; Tritium; Urinary Bladder; Vasopressins; Water

1972
The effect of sulfonylurea drugs on rabbit myocardial contractility, canine purkinje fiber automaticity, and adenyl cyclase activity from rabbit and human hearts.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:9

    Topics: Acetohexamide; Adenylyl Cyclases; Animals; Chlorpropamide; Culture Techniques; Cyclic AMP; Dogs; Heart; Heart Atria; Heart Conduction System; Humans; Membrane Potentials; Microelectrodes; Myocardium; Phenformin; Propranolol; Rabbits; Stimulation, Chemical; Sulfonylurea Compounds; Theophylline; Tolazamide; Tolbutamide

1972
Modulation of adenyl cyclase action in toad bladder by chlorpropamide: antagonism to prostaglandin E.
    European journal of pharmacology, 1973, Volume: 22, Issue:3

    Topics: Adenylyl Cyclases; Animals; Bufo marinus; Chlorpropamide; Cyclic AMP; In Vitro Techniques; Osmosis; Prostaglandin Antagonists; Prostaglandins; Theophylline; Urinary Bladder; Vasopressins; Water

1973
Effect of chlorpropamide on osmotic water flow across toad bladder and the response to vasopressin, theophylline and cyclic AMP.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 38, Issue:5

    Topics: Animals; Biological Transport; Bufo marinus; Chlorpropamide; Cyclic AMP; Diuresis; Osmosis; Theophylline; Urinary Bladder; Vasopressins; Water

1974
Effects of ADH and other agents on cyclic AMP accumulation in toad bladder epithelium.
    The American journal of physiology, 1974, Volume: 226, Issue:5

    Topics: Animals; Bufo marinus; Calcium; Chlorpropamide; Cyclic AMP; Epithelium; In Vitro Techniques; Norepinephrine; Prostaglandins; Proteins; Theophylline; Time Factors; Urinary Bladder; Vasopressins

1974
The physiological availability of methamphetamine HCl.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 4, Issue:2

    Topics: Aminobenzoates; Benzoates; Binding Sites; Biopharmaceutics; Chlorpropamide; Dialysis; Drug Interactions; Mathematics; Methamphetamine; Nitro Compounds; Protein Binding; Quinacrine; Quinolinium Compounds; Salicylates; Serum Albumin, Bovine; Theophylline

1972
Adverse drug reactions in the elderly: case studies.
    Geriatrics, 1984, Volume: 39, Issue:12

    Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonidine; Dienestrol; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydralazine; Lung Diseases; Male; Middle Aged; Nitrofurantoin; Pancreatitis; Papaverine; Peripheral Nervous System Diseases; Procainamide; Propranolol; Sulindac; Theophylline; Timolol

1984
Identification of calmodulin-like activity in human seminal plasma.
    Biochemical and biophysical research communications, 1980, Feb-12, Volume: 92, Issue:3

    Topics: Amitriptyline; Biological Transport, Active; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Calmodulin; Cell Membrane; Chlorpropamide; Erythrocyte Membrane; Erythrocytes; Hot Temperature; Humans; Kinetics; Magnesium; Male; Semen; Theophylline; Trypsin

1980
[EFFECTS OF VARIOUS NATURAL ORGANIC SUBSTANCES AND AMINO ACIDS ON THE BLOOD SURGAR LEVEL AND EXPERIMENTAL STUDIES ON ORAL HYPOGLYCEMIC AGENTS].
    Nihon Naibunpi Gakkai zasshi, 1963, Nov-20, Volume: 39

    Topics: Amino Acids; Animals; Bile Acids and Salts; Blood Chemical Analysis; Blood Glucose; Caffeine; Chlorpropamide; Creatine; Creatinine; Cystine; Diabetes Mellitus, Experimental; Hippurates; Hypoglycemic Agents; Injections; Injections, Intravenous; Metformin; Pathology; Pharmacology; Rats; Research; Salts; Theobromine; Theophylline; Tyrosine

1963