theophylline has been researched along with chlorpheniramine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (28.57) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 13 (37.14) | 29.6817 |
| 2010's | 5 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Beranger, S; Désiles, JP; Pascal, JC; Pinhas, H; Poizot, A | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Caron, G; Ermondi, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Le Fur, G; Uzan, A | 1 |
| Kopcha, M; Lordi, NG | 1 |
| Buckley, NM; Diamant, S; Frasier, ID; Owusu, K | 1 |
| Goto, S; Inagaki, N; Koda, A; Nagai, H | 1 |
| Floro, LD; Hyde, JS | 1 |
| Wellens, D | 1 |
| Kawamura, K; Onishi, R; Yamamoto, K | 1 |
| el Sayed, F; Lievens, P; Lulling, J | 1 |
| Johnson, S; Lewiston, NJ; Sloan, E | 1 |
| Emery, DL; McClure, SJ | 1 |
| Cooney, DO | 1 |
| Häglund, BO; Sundelöf, LO; Upadrashta, SM | 1 |
| Brown, C; Gentile, DA; Skoner, DP | 1 |
| McGinity, JW; Wu, C | 1 |
| Ishizaki, T; Zhao, XJ | 1 |
| Cartilier, L; Chebli, C | 1 |
| Aiedeh, K; Taha, MO | 2 |
| Peppas, NA; Siepmann, J | 1 |
| Bodmeier, R; Wesseling, M | 1 |
| Boskabady, MH; Ramazani, M; Tabei, T | 1 |
| Arai, I; Hashimoto, Y; Kurachi, M; Takano, N | 1 |
1 review(s) available for theophylline and chlorpheniramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for theophylline and chlorpheniramine
| Article | Year |
|---|---|
Theophylline and chlorpheniramine in childhood asthma. Dose requirements for children 6 to 12 years (therapeutic orphans) and young adults 13 to 18 years of age receiving cromolyn sodium prophylaxis.
Topics: Adolescent; Age Factors; Asthma; Bronchodilator Agents; Child; Chlorpheniramine; Clinical Trials as Topic; Cromolyn Sodium; Ephedrine; Histamine H1 Antagonists; Humans; Placebos; Rhinitis, Allergic, Seasonal; Theophylline | 1974 |
In vitro modulation of platelet sodium, potassium adenosine triphosphatase enzyme activity by antiallergy drugs.
Topics: Adult; Albuterol; Blood Platelets; Chlorpheniramine; Cromolyn Sodium; Humans; Hydrocortisone; Hypersensitivity; Male; Sodium-Potassium-Exchanging ATPase; Theophylline | 1993 |
32 other study(ies) available for theophylline and chlorpheniramine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
New antihistaminic theophylline or theobromine derivatives.
Topics: Acetylcholine; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Histamine H1 Antagonists; Male; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains; Serotonin Antagonists; Skin Tests; Structure-Activity Relationship; Theobromine; Theophylline | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Inhibition of 3', 5'-cyclic AMP phosphodiesterase in the guinea pig lung by a new anti-allergic: 10-(3-quinuclidinylmethyl) phenothiazine (LM 209)].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Chlorpheniramine; Cromolyn Sodium; Dexamethasone; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Phenothiazines; Phosphodiesterase Inhibitors; Promethazine; Quinuclidines; Theophylline | 1976 |
Effect of physical and chemical properties on drug release from selected thermosoftening vehicles.
Topics: Calorimetry, Differential Scanning; Chlorpheniramine; Diffusion; Drug Delivery Systems; Excipients; Fats; Oils; Parabens; Salicylates; Salicylic Acid; Temperature; Theophylline | 1992 |
Histamine or adenosine blockade alters intestinal blood flow autoregulation in swine.
Topics: Adenosine; Animals; Chlorpheniramine; Homeostasis; Intestines; Receptors, Cell Surface; Receptors, Histamine; Receptors, Histamine H1; Regional Blood Flow; Renal Circulation; Swine; Theophylline | 1988 |
Pharmacological characterization of mouse ear PCA.
Topics: Albuterol; Animals; Ascaris; Chlorpheniramine; Chromones; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Ear; Female; Histamine H1 Antagonists; Isoproterenol; Ketotifen; Male; Methysergide; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Passive Cutaneous Anaphylaxis; Serotonin Antagonists; Serum Albumin, Bovine; SRS-A; Theophylline; Tissue Extracts | 1985 |
Pharmacological reactivity of an isolated tracheal preparation of the guinea-pig.
Topics: Acetylcholine; Animals; Atropine; Barium; Chlorisondamine; Chlorpheniramine; Diphenhydramine; Ethanolamines; Guinea Pigs; Hexamethonium Compounds; Histamine; In Vitro Techniques; Isoproterenol; Muscle Contraction; Papaverine; Scopolamine; Serotonin; Theophylline; Trachea | 1966 |
[Studies on analysis of mixed anti-cold pharmaceutical preparations. IX. Application of countercurrent distribution method].
Topics: Caffeine; Chlorpheniramine; Codeine; Countercurrent Distribution; Ephedrine; Methods; Solubility; Theophylline | 1971 |
Ventilatory mechanics in the dog. Its application to quantitative study of bronchomotor active drugs.
Topics: Acetylcholine; Animals; Atropine; Chlorpheniramine; Computers, Analog; Dogs; Female; Histamine; Lung; Male; Respiratory Function Tests; Serotonin; Theophylline | 1967 |
Effect of antihistamine on pulmonary function of children with asthma.
Topics: Adolescent; Adult; Asthma; Child; Chlorpheniramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Respiration; Rhinitis, Allergic, Seasonal; Theophylline | 1982 |
Studies on the inhibition of rejection of Trichostrongylus colubriformis larvae from immune sheep.
Topics: Animals; Azepines; Chlorpheniramine; Cyclosporine; Dexamethasone; Indomethacin; Larva; Piroxicam; Rejection, Psychology; Sheep; Sheep Diseases; Theophylline; Triazoles; Trichostrongylosis; Trichostrongylus | 1995 |
In vitro adsorption of phenobarbital, chlorpheniramine maleate, and theophylline by four commercially available activated charcoal suspensions.
Topics: Adsorption; Charcoal; Chlorpheniramine; Phenobarbital; Theophylline | 1995 |
Diffusion and concentration profiles of drugs in gels.
Topics: Acetaminophen; Chlorpheniramine; Diffusion; Gels; Humans; Ibuprofen; Indomethacin; Pharmacokinetics; Temperature; Theophylline | 1993 |
Non-traditional plasticization of polymeric films.
Topics: Chlorpheniramine; Ibuprofen; Parabens; Plasticizers; Polymers; Tablets; Tensile Strength; Theophylline; Thermal Conductivity | 1999 |
An in-vitro study on the metabolism of rokitamycin and possible interactions of the drug with rat liver microsomes.
Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Chlorpheniramine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Kinetics; Macrolides; Microsomes, Liver; Miocamycin; Oxidoreductases, N-Demethylating; Rats; Theophylline | 1999 |
Effect of some physical parameters on the sustained drug-release properties of substituted amylose matrices.
Topics: Acetaminophen; Algorithms; Amylose; Analgesics, Non-Narcotic; Anti-Allergic Agents; Bronchodilator Agents; Chemical Phenomena; Chemistry, Physical; Chlorpheniramine; Delayed-Action Preparations; Drug Compounding; Excipients; Pressure; Solubility; Theophylline | 2000 |
Synthesis of iron-crosslinked hydroxamated alginic acid and its in vitro evaluation as a potential matrix material for oral sustained-release beads.
Topics: Acetaminophen; Alginates; Chlorpheniramine; Cross-Linking Reagents; Delayed-Action Preparations; Drug Carriers; Hydroxamic Acids; Spectrophotometry, Infrared; Theophylline | 2000 |
Hydrophilic matrices for controlled drug delivery: an improved mathematical model to predict the resulting drug release kinetics (the "sequential layer" model).
Topics: Chemistry, Pharmaceutical; Chlorpheniramine; Delayed-Action Preparations; Diffusion; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Reproducibility of Results; Solubility; Theophylline; Water | 2000 |
Synthesis of iron-crosslinked chitosan succinate and iron-crosslinked hydroxamated chitosan succinate and their in vitro evaluation as potential matrix materials for oral theophylline sustained-release beads.
Topics: Administration, Oral; Bronchodilator Agents; Chemistry, Pharmaceutical; Chitin; Chitosan; Chlorpheniramine; Delayed-Action Preparations; Drug Delivery Systems; Hydroxamic Acids; Iron; Solubility; Theophylline | 2001 |
Influence of plasticization time, curing conditions, storage time, and core properties on the drug release from Aquacoat-coated pellets.
Topics: Cellulose; Chlorpheniramine; Citrates; Colloids; Delayed-Action Preparations; Drug Implants; Drug Storage; Excipients; Histamine H1 Antagonists; Phosphodiesterase Inhibitors; Plasticizers; Theophylline | 2001 |
Relaxant effects of different fractions of essential oil from Carum copticum on guinea pig tracheal chains.
Topics: Animals; Bronchodilator Agents; Carum; Chlorpheniramine; Dose-Response Relationship, Drug; Ethanol; Guinea Pigs; Male; Methacholine Chloride; Muscle Relaxation; Muscle, Smooth; Phytotherapy; Plant Oils; Propranolol; Theophylline; Trachea | 2003 |
Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice.
Topics: Alprostadil; Animals; Antipruritics; Behavior, Animal; Capsaicin; Chlorpheniramine; Cyproheptadine; Dermatitis, Atopic; Dexamethasone; Dibucaine; Male; Mice; Mice, Inbred Strains; Naloxone; Pinacidil; Pruritus; Tacrolimus; Theophylline; Time Factors | 2004 |