theophylline has been researched along with chlordiazepoxide in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (60.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 7 (23.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chasin, M; Free, CA; Harris, DN; Hess, SM | 1 |
| Borowitz, JL; Peyton, JC | 1 |
| Holtzman, SG; Mumford, GK | 1 |
| Coffin, VL; Spealman, RD | 1 |
| Johnson, RF; Meredith, CG; Schenker, S; Secor, JW; Snowdy, P; Speeg, KV | 1 |
| Holloway, FA; Michaelis, RC; Modrow, HE | 1 |
| Brown, MW; Maldonado, AL; Meredith, CG; Speeg, KV | 1 |
| Christian, CD; Davis, GL; Johnson, RF; Meredith, CG; Schenker, S; Troxell, R | 1 |
| Schultz, J | 1 |
| Corsico, N; Martelli, EA | 1 |
| Beer, B; Chasin, M; Clody, DE; Vogel, JR | 1 |
| Knepil, J | 1 |
| Diemath, HE; Enge, S; Lechner, H | 1 |
| Babb, RR | 1 |
| FRIEDMAN, HT | 1 |
| THOMAS, JW | 1 |
| BLOOM, S; MARKOW, H | 1 |
| Abraham, R; Jayarajan, P; Kancharla, B; Nirogi, R; Shanmuganathan, D | 1 |
2 review(s) available for theophylline and chlordiazepoxide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Modulators of cyclic AMP systems.
Topics: Adenylyl Cyclase Inhibitors; Animals; Anti-Anxiety Agents; Anti-Infective Agents; Antipsychotic Agents; Benzodiazepines; Brain; Cats; Cells, Cultured; Chlordiazepoxide; Cyclic AMP; Guinea Pigs; Humans; In Vitro Techniques; Meprobamate; Papaverine; Phenothiazines; Phosphodiesterase Inhibitors; Platelet Aggregation; Pyridines; Rats; Stimulation, Chemical; Theophylline | 1975 |
1 trial(s) available for theophylline and chlordiazepoxide
| Article | Year |
|---|---|
An anti-asthmatic combination.
Topics: Adolescent; Adult; Aged; Asthma; Chlordiazepoxide; Clinical Trials as Topic; Drug Combinations; Ephedrine; Female; Humans; Male; Middle Aged; Phenobarbital; Theophylline | 1972 |
27 other study(ies) available for theophylline and chlordiazepoxide
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Chlordiazepoxide and theophylline alter calcium levels in subcellular fractions of rat brain cortex.
Topics: Animals; Calcium; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Male; Microsomes; Mitochondria; Rats; Subcellular Fractions; Synaptosomes; Theophylline | 1979 |
Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat?
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbolines; Chlordiazepoxide; Electric Stimulation; Hypothalamic Area, Lateral; Male; Midazolam; Phenylisopropyladenosine; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reinforcement, Psychology; Self Stimulation; Sensory Thresholds; Theophylline; Triazoles | 1991 |
Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Chlordiazepoxide; Conditioning, Psychological; Male; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Saimiri; Theobromine; Theophylline; Xanthines | 1985 |
Lack of effect of nizatidine on hepatic drug metabolism in man.
Topics: Adult; Blood Proteins; Caffeine; Chlordiazepoxide; Histamine H2 Antagonists; Humans; Kinetics; Liver; Lorazepam; Male; Nizatidine; Pharmaceutical Preparations; Protein Binding; Theophylline; Thiazoles | 1985 |
Methylxanthine discrimination in the rat: possible benzodiazepine and adenosine mechanisms.
Topics: Animals; Caffeine; Chlordiazepoxide; Conditioning, Operant; Cues; Discrimination Learning; Male; Papaverine; Pentobarbital; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Theophylline | 1985 |
Effect of ketoconazole on hepatic oxidative drug metabolism.
Topics: Adult; Chlordiazepoxide; Drug Interactions; Half-Life; Humans; Injections, Intravenous; Ketoconazole; Kinetics; Liver; Male; Mixed Function Oxygenases; Theophylline | 1985 |
Effects of influenza virus vaccine on hepatic drug metabolism.
Topics: Adult; Chlordiazepoxide; Chromatography, High Pressure Liquid; Half-Life; Humans; Influenza Vaccines; Interferon Type I; Kinetics; Liver; Lorazepam; Male; Regression Analysis; Theophylline | 1985 |
Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig and rat.
Topics: Adenosine; Animals; Benzyl Compounds; Cerebral Cortex; Chlordiazepoxide; Cyclic AMP; Diazepam; Ethers; Guinea Pigs; Histamine; Hydrazines; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Oxazepam; Phosphodiesterase Inhibitors; Pyrazoles; Pyridines; Rats; Species Specificity; Theophylline | 1974 |
On the mechanism of lipomobilizing effect of chlordiazepoxide.
Topics: Animals; Chlordiazepoxide; Cyclic AMP; Drug Synergism; Fatty Acids, Nonesterified; Female; Norepinephrine; Rats; Theophylline | 1969 |
Cyclic adenosine monophosphate phosphodiesterase in brain: effect on anxiety.
Topics: Animals; Anxiety; Barbiturates; Brain; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Cyclic AMP; Diazepam; Humans; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Punishment; Rats; Theobromine; Theophylline; Tranquilizing Agents | 1972 |
A sensitive, specific method for measuring N-acetyl-p-aminophenol (paracetamol) in blood.
Topics: Acetaminophen; Amobarbital; Chlordiazepoxide; Evaluation Studies as Topic; Humans; Indicators and Reagents; Methods; Microchemistry; Pentobarbital; Phenobarbital; Salicylates; Spectrophotometry, Ultraviolet; Theophylline | 1974 |
EEG depth leads during stereotaxic brain surgery. A report on 117 cases (5 target points, effects of 13 different drugs).
Topics: Amides; Amygdala; Antimetabolites; Asparagine; Benzoates; Brain; Brain Diseases; Cerebrovascular Circulation; Child; Chlordiazepoxide; Diazepam; Dihydroxyphenylalanine; Electroencephalography; Female; Fluphenazine; Gyrus Cinguli; Hippocampus; Humans; Hyperkinesis; Male; Methanol; Middle Aged; Parkinson Disease; Pyridines; Pyridoxine; Spasm; Stereotaxic Techniques; Thalamic Nuclei; Theophylline; Tranquilizing Agents; Triflupromazine; Vasodilator Agents | 1970 |
Drug interactions with cimetidine.
Topics: Chlordiazepoxide; Cimetidine; Diazepam; Drug Interactions; Guanidines; Humans; Phenytoin; Propranolol; Theophylline; Warfarin | 1981 |
Librium-theophylline-ephedrine compound in bronchial asthma. A double blind study in 100 patients.
Topics: Asthma; Chlordiazepoxide; Double-Blind Method; Ephedrine; Humans; Theophylline | 1963 |
Resprium (Librium-theophylline-ephedrine compound) in the treatment of bronchial asthma and respiratory allergy.
Topics: Asthma; Chlordiazepoxide; Ephedrine; Humans; Respiratory Hypersensitivity; Theophylline; Tranquilizing Agents | 1962 |
EVALUATION OF A CHLORDIAZEPOXIDE, THEOPHYLLINE, EPHEDRINE COMBINATION IN THE TREATMENT OF BRONCHIAL ASTHMA.
Topics: Asthma; Chlordiazepoxide; Ephedrine; Humans; Theophylline | 1963 |
Comparison of whole body and head out plethysmography using respiratory stimulant and depressant in conscious rats.
Topics: Animals; Chlordiazepoxide; Male; Models, Animal; Plethysmography; Plethysmography, Whole Body; Propranolol; Rats; Rats, Wistar; Respiratory Function Tests; Respiratory Physiological Phenomena; Respiratory Rate; Theophylline; Tidal Volume | 2012 |