theophylline and cephalexin

theophylline has been researched along with cephalexin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's3 (15.00)18.2507
2000's7 (35.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gubernator, K; Kansy, M; Senner, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Botta, M; Dreassi, E; Falchi, F; Maga, G; Santucci, A; Schenone, S; Zizzari, AT1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Friedman, P; Greenblatt, DJ; Pfeifer, HJ1
Abate, MA; Hammond, D1
Bachmann, K; Forney, RB; Jauregui, L; Schwartz, J1
Hempenius, J; Holtkamp, A; Jonkman, JH; Schoenmaker, R; van der Boon, WJ2
Haruta, S; Higaki, K; Kimura, T; Kurosaki, Y; Sawamoto, T1
Haruta, S; Higaki, K; Iwasaki, N; Kimura, T; Ogawara, K1
Barbero, N; Pontremoli, C; Viscardi, G; Visentin, S1

Reviews

1 review(s) available for theophylline and cephalexin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

19 other study(ies) available for theophylline and cephalexin

ArticleYear
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet

1998
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Humans; Lipids; Membranes, Artificial; Permeability; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrimidines

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Effects of three antibiotics on theophylline kinetics.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:1

    Topics: Adult; Aminophylline; Cephalexin; Drug Interactions; Erythromycin; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Tetracycline; Theophylline

1979
Theophylline toxicity, acute illness, and cefaclor administration.
    DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:4

    Topics: Acute Disease; Cefaclor; Cephalexin; Child; Drug Interactions; Humans; Male; Theophylline; Virus Diseases

1989
Impact of cefaclor on the pharmacokinetics of theophylline.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:2

    Topics: Adult; Cefaclor; Cephalexin; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Theophylline

1986
Clinical pharmacokinetics of theophylline during co-treatment with cefaclor.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:2

    Topics: Adult; Cefaclor; Cephalexin; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Theophylline; Time Factors

1986
No effect of cefaclor on theophylline pharmacokinetics.
    European journal of respiratory diseases, 1985, Volume: 66, Issue:1

    Topics: Adult; Cefaclor; Cephalexin; Female; Humans; Kinetics; Male; Theophylline

1985
Prediction of the plasma concentration profiles of orally administered drugs in rats on the basis of gastrointestinal transit kinetics and absorbability.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:4

    Topics: Administration, Oral; Ampicillin; Animals; Area Under Curve; Biological Availability; Cephalexin; Cephalosporins; Chromatography, High Pressure Liquid; Gastrointestinal Transit; Intestinal Absorption; Male; Penicillins; Pharmacokinetics; Phenolsulfonphthalein; Propranolol; Rats; Rats, Wistar; Theophylline; Vasodilator Agents

1997
Absorption behavior of orally administered drugs in rats treated with propantheline.
    Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:9

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Area Under Curve; Bronchodilator Agents; Cephalexin; Gastrointestinal Motility; Intestinal Absorption; Male; Models, Biological; Muscarinic Antagonists; Propantheline; Rats; Rats, Wistar; Theophylline

1998
Mucin-drugs interaction: The case of theophylline, prednisolone and cephalexin.
    Bioorganic & medicinal chemistry, 2015, Oct-15, Volume: 23, Issue:20

    Topics: Animals; Binding Sites; Cephalexin; Molecular Structure; Mucins; Prednisolone; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stomach; Swine; Theophylline; Thermodynamics

2015