theophylline and bumetanide

theophylline has been researched along with bumetanide in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (16.13)	18.7374
1990's	6 (19.35)	18.2507
2000's	9 (29.03)	29.6817
2010's	11 (35.48)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Olesen, KH; Sigurd, B	2
Clancy, JP; Li, M; McCann, JD; Welsh, MJ	1
Andersen, V; Munck, BG; Munck, LK; Skadhauge, E	1
al-Bazzaz, FJ; Farah, M; Tarka, C	1
Gott, AL; Gray, SM; James, AF; Leese, HJ	1
Epstein, FH; Rosa, R; Silva, P; Solomon, RJ; Taylor, M	1
Field, M; Nash, NT; Rao, MC	1
Hansen, MB	1
Field, M; Minhas, BS; Sullivan, SK	1
Bajnath, RB; Bouritius, H; Groot, JA	1
Fang, X; Gao, N; Hu, HZ; Liu, S; Wang, GD; Wang, XY; Wood, JD; Xia, Y	1
Chao, PC; Hamilton, KL	1
Bindslev, N; Hansen, MB; Kaltoft, N; Osbak, PS; Poulsen, SS; Tilotta, MC; Witte, AB	1

Reviews

1 review(s) available for theophylline and bumetanide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for theophylline and bumetanide

Article	Year
Comparative natriuretic and diuretic efficacy of theophylline ethylenediamine and of bendroflumethiazide during long-term treatment with the potent diuretic bumetanide. Permutation trial tests in patients with congestive heart failure. Acta medica Scandinavica, 1978, Volume: 203, Issue:1-2 Topics: Bendroflumethiazide; Bumetanide; Clinical Trials as Topic; Diuresis; Diuretics; Drug Evaluation; Drug Therapy, Combination; Electrolytes; Ethylenediamines; Female; Heart Failure; Humans; Male; Middle Aged; Natriuresis; Theophylline; Time Factors	1978

Article

Year

Comparative natriuretic and diuretic efficacy of theophylline ethylenediamine and of bendroflumethiazide during long-term treatment with the potent diuretic bumetanide. Permutation trial tests in patients with congestive heart failure.

Acta medica Scandinavica, 1978, Volume: 203, Issue:1-2

Topics: Bendroflumethiazide; Bumetanide; Clinical Trials as Topic; Diuresis; Diuretics; Drug Evaluation; Drug Therapy, Combination; Electrolytes; Ethylenediamines; Female; Heart Failure; Humans; Male; Middle Aged; Natriuresis; Theophylline; Time Factors

1978

Other Studies

29 other study(ies) available for theophylline and bumetanide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
The supra-additive natriuretic effect addition of theophylline ethylenediamine and bumetanide in congestive heart failure. Permutation trial tests in patients in long-term treatment with bumetanide. American heart journal, 1977, Volume: 94, Issue:2 Topics: Adult; Bumetanide; Diuretics; Drug Therapy, Combination; Ethylenediamines; Heart Failure; Humans; Long-Term Care; Natriuresis; Theophylline; Water-Electrolyte Balance	1977
Calcium-dependent regulation of airway epithelial chloride channels. The American journal of physiology, 1990, Volume: 258, Issue:2 Pt 1 Topics: Animals; Bumetanide; Calcimycin; Calcium; Cells, Cultured; Chloride Channels; Chlorides; Cyclic AMP; Dogs; Epithelium; Indomethacin; Iodides; Ion Channels; Isoproterenol; Kinetics; Membrane Proteins; Muscle, Smooth; Nitrobenzoates; Potassium; Theophylline; Trachea; Valinomycin	1990
In vitro studies of theophylline-induced changes in Na, K and Cl transport in hen (Gallus domesticus) colon suggesting bidirectional, basolateral NaK2Cl cotransport. Comparative biochemistry and physiology. A, Comparative physiology, 1990, Volume: 96, Issue:1 Topics: Animals; Biological Transport; Bumetanide; Chickens; Chlorides; Colon; Female; Intestinal Mucosa; Potassium; Sodium; Theophylline	1990
Microperfusion of sheep bronchioles. The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1 Topics: Acetazolamide; Amiloride; Animals; Biological Transport; Bronchi; Bumetanide; Cattle; Dogs; Epinephrine; Furosemide; In Vitro Techniques; Ions; Isoproterenol; Microscopy, Electron; Models, Biological; Ouabain; Perfusion; Rabbits; Respiratory Physiological Phenomena; Sheep; Species Specificity; Swine; Theophylline	1991
The mechanism and control of rabbit oviduct fluid formation. Biology of reproduction, 1988, Volume: 39, Issue:4 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Body Fluids; Bucladesine; Bumetanide; Calcimycin; Cholera Toxin; Colforsin; Fallopian Tubes; Female; Perfusion; Phorbol 12,13-Dibutyrate; Rabbits; Theophylline	1988
In vivo effect of volume expansion on rectal gland function. II. Hemodynamic changes. The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 2 Topics: Animals; Bucladesine; Bumetanide; Cyclic AMP; Dogfish; Female; Hemodynamics; Male; Oxygen Consumption; Regional Blood Flow; Salt Gland; Somatostatin; Theophylline; Water-Electrolyte Balance	1984
Differing effects of cGMP and cAMP on ion transport across flounder intestine. The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bumetanide; Chlorides; Cyclic AMP; Cyclic GMP; Fishes; Intestinal Absorption; Potassium; Rubidium; Sodium; Theophylline	1984
ICS 205-930 reduces 5-methoxytryptamine-induced short-circuit current in stripped pig jejunum. Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:3 Topics: 5-Methoxytryptamine; Animals; Atropine; Bumetanide; Drug Interactions; Electrophysiology; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indoles; Jejunum; Kinetics; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Swine; Tetrodotoxin; Theophylline; Tropisetron	1994
Bicarbonate secretion in rabbit ileum: electrogenicity, ion dependence, and effects of cyclic nucleotides. Gastroenterology, 1993, Volume: 105, Issue:6 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bicarbonates; Bumetanide; Chlorides; Cyclic GMP; Ethoxzolamide; Ileum; In Vitro Techniques; Male; Rabbits; Sodium; Theophylline	1993
Microelectrode measurements of the effects of basolateral adenosine in polarized human intestinal epithelial cells in culture. Pflugers Archiv : European journal of physiology, 1999, Volume: 437, Issue:4 Topics: Acetophenones; Adenosine; Bumetanide; Cell Line; Cell Membrane; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Humans; Intestines; Membrane Potentials; Microelectrodes; Phospholipases A; Phospholipases A2; Receptors, Purinergic P1; Theophylline	1999
Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine. European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bumetanide; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Electrolytes; Gene Expression; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Vasoactive Intestinal Polypeptide, Type I; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors; Tetrodotoxin; Theophylline; Triazines; Triazoles; Vasoactive Intestinal Peptide	2006
Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum. American journal of physiology. Cell physiology, 2009, Volume: 297, Issue:3 Topics: Animals; Bumetanide; Chloride-Bicarbonate Antiporters; Electrophysiology; Genistein; Jejunum; Male; Mice; Milrinone; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Sodium Potassium Chloride Symporter Inhibitors; Theophylline	2009
Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia. BMC gastroenterology, 2010, Jan-26, Volume: 10 Topics: Alprostadil; Biopsy; Bumetanide; Colforsin; Colon; Colorectal Neoplasms; Dinoprostone; Female; Humans; Ion Transport; Lubiprostone; Male; Middle Aged; Ouabain; Prostaglandin-Endoperoxide Synthases; Receptors, Prostaglandin E; Reference Values; Signal Transduction; Tamoxifen; Theophylline	2010