theophylline and baclofen

theophylline has been researched along with baclofen in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's7 (30.43)18.2507
2000's5 (21.74)29.6817
2010's5 (21.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Rothman, SM; Yoon, KW1
Sawynok, J; Steardo, L1
Dolphin, AC; Forda, SR; Scott, RH1
Kharin, NA; Komissarov, IV; Serdiuk, SE1
Dickson, C; Sawynok, J1
Sawynok, J1
Hosseinzadeh, H; Stone, TW1
Nicoll, RA; Perkel, DJ1
Cotman, CW; Kahle, JS1
Dunwiddie, TV; Lupica, CR; Mitchell, JB1
Cui, JG; Linderoth, B; Meyerson, BA; Sollevi, A1
Amabeoku, GJ1
Kang, JH; Kang, JS; Kim, BS; Koh, HC; Lee, H; Om, SA; Shin, IC1
Kimura, M; Saitoh, N; Takahashi, T1
Andreasen, M; Hablitz, JJ; Nedergaard, S; Skov, J1
Grant, C; Marks, L; Prior, H; South, M1

Reviews

1 review(s) available for theophylline and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for theophylline and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:5

    Topics: Adenosine; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Evoked Potentials; Hippocampus; Rats; Synapses; Synaptic Transmission; Theophylline

1991
Clonidine reverses methylxanthine-induced potentiation of baclofen antinociception.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Baclofen; Clonidine; Drug Interactions; Male; Neural Pathways; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Reaction Time; Theophylline

1985
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.
    The Journal of physiology, 1986, Volume: 373

    Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Action Potentials; Adenosine; Adenylyl Cyclases; Animals; Baclofen; Calcium; Cells, Cultured; Depression, Chemical; Ganglia, Spinal; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline

1986
[Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 104, Issue:7

    Topics: Adenosine; Animals; Baclofen; Clonidine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Myenteric Plexus; Receptors, Cholinergic; Receptors, Neurotransmitter; Theophylline

1987
Involvement of GABA in the antinociceptive effect of gamma-acetylenic GABA (GAG), an inhibitor of GABA-transaminase.
    General pharmacology, 1983, Volume: 14, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Analgesics; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Theophylline; Time Factors

1983
Theophylline-induced potentiation of the antinociceptive action of baclofen.
    British journal of pharmacology, 1983, Volume: 78, Issue:2

    Topics: Analgesics; Animals; Baclofen; Caffeine; Drug Synergism; Male; Rats; Rats, Inbred Strains; Reaction Time; Theophylline

1983
A paradoxical inhibitory effect of xanthines on hippocampal excitability in calcium-free media.
    Brain research, 1994, Sep-19, Volume: 657, Issue:1-2

    Topics: Adenosine; Animals; Baclofen; Calcium; Carbamazepine; Culture Media; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Wistar; Theophylline; Xanthines

1994
Evidence for all-or-none regulation of neurotransmitter release: implications for long-term potentiation.
    The Journal of physiology, 1993, Volume: 471

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neurotransmitter Agents; Pyramidal Cells; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Theophylline

1993
L-2-amino-4-phosphonobutanoic acid and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid reduce paired-pulse depression recorded from medial perforant path in the dentate gyrus of rat hippocampal slices.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:1

    Topics: Aminobutyrates; Animals; Atropine; Baclofen; Carbachol; Cycloleucine; Depression, Chemical; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neural Pathways; Neurotransmitter Uptake Inhibitors; Picrotoxin; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Theophylline

1993
Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:8

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Baclofen; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; Male; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic; Synapses; Theophylline

1993
Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation.
    Neuroscience letters, 1998, May-15, Volume: 247, Issue:2-3

    Topics: Adenosine; Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hindlimb; Hyperesthesia; Male; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Theophylline

1998
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
    General pharmacology, 1999, Volume: 32, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline

1999
Mediation of the cardiovascular response to spinal gamma-aminobutyric acid(B) receptor stimulation by adenosine A(1) receptors in anesthetized rats.
    Neuroscience letters, 2000, Dec-22, Volume: 296, Issue:2-3

    Topics: Adenosine; Amino Acids, Neutral; Animals; Baclofen; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Spinal Cord; Sympathetic Nervous System; Theobromine; Theophylline

2000
Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
    The Journal of physiology, 2003, Dec-01, Volume: 553, Issue:Pt 2

    Topics: Adenosine; Animals; Auditory Pathways; Baclofen; Blotting, Western; Brain Stem; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Neural Inhibition; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Synaptophysin; Tetrodotoxin; Theophylline

2003
Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.
    Cellular and molecular neurobiology, 2011, Volume: 31, Issue:4

    Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Amino Acids; Animals; Baclofen; Barium; Bee Venoms; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cesium; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Potassium Channel Blockers; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Theophylline; Xanthenes

2011
Incorporation of capillary microsampling into whole body plethysmography and modified Irwin safety pharmacology studies in rats.
    Regulatory toxicology and pharmacology : RTP, 2015, Volume: 73, Issue:1

    Topics: Animals; Baclofen; Blood Specimen Collection; Male; Plethysmography, Whole Body; Rats; Rats, Wistar; Respiratory System; Theophylline

2015