theophylline and azelastine

theophylline has been researched along with azelastine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's5 (29.41)18.2507
2000's4 (23.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bachelet, M; Hatmi, M; Havet, N; Vargaftig, BB1
Chand, N; Diamantis, W; Nolan, K; Sofia, RD1
Arimura, A; Inagaki, N; Koda, A; Miura, T; Mori, H; Nagai, H; Sakamoto, O1
Kurosawa, M1
Chand, N; Diamantis, W; Pillar, J; Sofia, RD3
Kuroiwa, H; Tomioka, S1
Kobayashi, S; Kurosawa, M; Okayama, Y1
Asamoto, H; Fujii, H; Horiuchi, Y; Iso, S; Kawakami, A; Kokura, M; Ohara, N; Ooishi, T; Sasaki, Y; Sawano, T1
Bucholtz, GA; Kemp, JP; Meltzer, EO; Middleton, E; Newton, JJ; Orgel, HA; Perhach, JL; Spector, SL; Welch, MJ1
Achterrath-Tuckermann, U; Szelenyi, I1
Bolsmann, K; Braam, U; Eichelberg, D; Greven, T; Jungbluth, C; Schmutzler, W; Zwadlo-Klarwasser, G1

Trials

1 trial(s) available for theophylline and azelastine

ArticleYear
A dose-response study of the bronchodilator action of azelastine in asthma.
    The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:6

    Topics: Adolescent; Adult; Asthma; Bronchodilator Agents; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Kinetics; Lung Volume Measurements; Middle Aged; Phthalazines; Pyridazines; Random Allocation; Theophylline

1987

Other Studies

16 other study(ies) available for theophylline and azelastine

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Azelastine potentiates the prostaglandin-induced increase of cyclic AMP content in human platelets and in guinea-pig alveolar macrophages.
    Prostaglandins, 1992, Volume: 43, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Blood Platelets; Cell Survival; Cyclic AMP; Dinoprostone; Drug Synergism; Epoprostenol; Guinea Pigs; Humans; In Vitro Techniques; Macrophages, Alveolar; Phthalazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Theophylline

1992
Inhibition of aeroallergen-induced bronchial eosinophilia by azelastine in guinea pigs.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:3

    Topics: Administration, Oral; Animals; Azepines; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Leukocyte Count; Leukocytes, Mononuclear; Male; Methylprednisolone; Phthalazines; Platelet Activating Factor; Pulmonary Eosinophilia; Theophylline; Triazoles

1992
A method for evaluating anti-allergic drugs by simultaneously induced passive cutaneous anaphylaxis and mediator cutaneous reactions.
    International archives of allergy and applied immunology, 1990, Volume: 92, Issue:3

    Topics: Albuterol; Animals; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Isoproterenol; Ketotifen; Male; ortho-Aminobenzoates; Passive Cutaneous Anaphylaxis; Phenothiazines; Phthalazines; Rats; Rats, Inbred Strains; Skin Tests; Theophylline

1990
Inhibitory effects of azelastine on protein kinase C and diphosphoinositide kinase in rat mast cells.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:2 Pt 1

    Topics: Adenine; Animals; Cytoplasmic Granules; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Leukocytes; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Phosphorus Radioisotopes; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Phthalazines; Protein Kinase C; Pyridazines; Rats; Rats, Inbred Strains; Theophylline

1990
Inhibition of allergic histamine release by azelastine and selected antiallergic drugs from rabbit leukocytes.
    International archives of allergy and applied immunology, 1985, Volume: 77, Issue:4

    Topics: Animals; Cromolyn Sodium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Ketotifen; Leukocytes; Male; Phthalazines; Pyridazines; Rabbits; Theophylline; Time Factors

1985
Inhibition of IgE-mediated allergic histamine release from rat peritoneal mast cells by azelastine and selected antiallergic drugs.
    Agents and actions, 1985, Volume: 16, Issue:5

    Topics: Animals; Astemizole; Benzimidazoles; Diphenhydramine; Histamine Release; Hypersensitivity; Immunoglobulin E; Ketotifen; Male; Mast Cells; Ovalbumin; Phosphatidylserines; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains; Theophylline

1985
Inhibition of allergic histamine release from rat peritoneal mast cells by azelastine. Interaction with selected antiasthmatic drugs.
    International archives of allergy and applied immunology, 1988, Volume: 86, Issue:3

    Topics: Albuterol; Animals; Cromolyn Sodium; Drug Interactions; Histamine H1 Antagonists; Histamine Release; Hypersensitivity; Male; Mast Cells; Peritoneal Cavity; Phthalazines; Prednisolone; Pyridazines; Rats; Rats, Inbred Strains; Theophylline

1988
[Therapeutic aspects of intractable asthma].
    Nihon Kyobu Shikkan Gakkai zasshi, 1988, Volume: 26, Issue:3

    Topics: Adult; Aged; Asthma; Cromolyn Sodium; Female; Humans; Ketotifen; Male; Middle Aged; ortho-Aminobenzoates; Phthalazines; Terbutaline; Theophylline

1988
Inhibitory effect of adenine nucleotides and anti-allergic drugs on phosphorylation of phosphatidylinositol in rat mast cell granules.
    Allergy, 1989, Volume: 44, Issue:8

    Topics: 1-Phosphatidylinositol 4-Kinase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cromolyn Sodium; Cytoplasmic Granules; Histamine H1 Antagonists; Ketotifen; Mast Cells; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Phthalazines; Rats; Theophylline

1989
[Effect of azelastine on theophylline clearance in asthma patients].
    Arerugi = [Allergy], 1988, Volume: 37, Issue:10

    Topics: Administration, Oral; Adult; Aged; Asthma; Delayed-Action Preparations; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Phthalazines; Pyridazines; Theophylline

1988
Interaction of azelastine with adenosine receptors in guinea pig trachea.
    Agents and actions, 1988, Volume: 23, Issue:3-4

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Phenylisopropyladenosine; Phthalazines; Pyridazines; Receptors, Purinergic; Theophylline; Trachea

1988
Histamine release from mast cells and monocytes: the effects of azelastine, reproterol and vitamin A-analogues.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45 Suppl 1

    Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; beta Carotene; Carotenoids; Dose-Response Relationship, Drug; Drug Combinations; Etretinate; Histamine H1 Antagonists; Histamine Release; Humans; Isotretinoin; Keratolytic Agents; Mast Cells; Metaproterenol; Monocytes; Phthalazines; Quinolines; Superoxide Dismutase; Theophylline

1996