theophylline and apomorphine

theophylline has been researched along with apomorphine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199015 (50.00)18.7374
1990's6 (20.00)18.2507
2000's5 (16.67)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lefebvre, RA; Willems, JL1
Honda, F; Notsu, Y; Satoh, H; Satoh, Y1
Pohto, P1
Georgiev, V; Markovska, V1
Georgiev, VP; Markovska, VL1
Agnati, LF; Corrodi, H; Everitt, BJ; Fuxe, K; Hökfelt, T; Löfström, A; Ungerstedt, U1
Paalzow, G; Paalzow, L1
Ferre, S; Fredholm, BB; Fuxe, K; Johansson, B; von Euler, G1
Nasir, T; Zarrindast, MR1
Brown, SJ; Evenden, JL; Gill, R; Iversen, SD; Richardson, PJ1
Baldessarini, RJ; Booth, RG1
Holtzman, SG1
Cadafalch, J; Casas, M; Ferré, S; Grau, JM; Jané, F1
Poursoltan, M; Zarrindast, MR1
Sheppard, H; Wiggan, G1
Laplace, JP; Ruckebusch, Y1
Furukawa, T; Katsuragi, T; Ushijima, I1
Fredholm, BB; Herrera-Marschitz, M; Jonzon, B; Lindström, K; Ungerstedt, U1
Ikeda, M; Watanabe, H; Watanabe, K1
Ferré, S; Giménez-Llort, L; Martínez, E1
Samini, M; Sharifzadeh, M; Zarrindast, MR1
Jurczyk, S; Katlabi, J; Malec, D; Modzelewski, J; Pawłowski, M1

Reviews

1 review(s) available for theophylline and apomorphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

29 other study(ies) available for theophylline and apomorphine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Gastric relaxation by apomorphine and ATP in the conscious dog.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:8

    Topics: Adenosine Triphosphate; Animals; Apomorphine; Dogs; Female; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Stomach; Theophylline

1979
Adenosine 3',5'-cyclic monophosphate as a possible mediator of rotational behaviour induced by dopaminergic receptor stimulation in rats lesioned unilaterally in the substantia nigra.
    European journal of pharmacology, 1976, Volume: 39, Issue:2

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Caudate Nucleus; Cyclic AMP; Denervation; Haloperidol; Male; Motor Activity; Rats; Receptors, Dopamine; Substantia Nigra; Theophylline

1976
A neuropharmacological approach to experimental bruxism.
    Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1977, Volume: 73, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Bromocriptine; Bruxism; Drug Synergism; Levodopa; Male; Mastication; Methylphenidate; Piribedil; Rats; Scopolamine; Theophylline; Time Factors

1977
Effects of apomorphine, pimoside, theophylline, meta-tolylcarbamide and diazepam on the picrotoxin convulsive-seizure threshold.
    Comptes rendus de l'Academie Bulgare des sciences : sciences mathematiques et naturelles, 1976, Volume: 29, Issue:11

    Topics: Animals; Apomorphine; Brain; Diazepam; Male; Mice; Phenylurea Compounds; Picrotoxin; Pimozide; Seizures; Theophylline

1976
Are the central dopaminergic synapses related to the convulsive-seizure threshold?--Effects of central dopaminergic drugs on the picrotoxin convulsive-seizure threshold. Interaction with diazepam, meta-tolylcarbamide and theophylline.
    Acta physiologica et pharmacologica Bulgarica, 1976, Volume: 2, Issue:4

    Topics: Animals; Apomorphine; Diazepam; Drug Interactions; Male; Mice; Phenylurea Compounds; Picrotoxin; Pimozide; Receptors, Dopamine; Seizures; Theophylline

1976
Action of dopamine receptor agonists in forebrain and hypothalamus: rotational behavior, ovulation, and dopamine turnover.
    Advances in neurology, 1975, Volume: 9

    Topics: Animals; Apomorphine; Brain; Caffeine; Dopamine; Ergot Alkaloids; Female; Hypothalamus; Limbic System; Lysergic Acid Diethylamide; Models, Biological; Motor Activity; Ovulation; Piribedil; Receptors, Drug; Sexual Behavior, Animal; Stimulation, Chemical; Telencephalon; Theophylline

1975
Enhancement of apomorphine-induced inhibition of vocalisation afterdischarge response by theophylline.
    Life sciences, 1975, Oct-10, Volume: 17, Issue:7

    Topics: Animals; Apomorphine; Depression, Chemical; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Levodopa; Male; Pain; Pimozide; Rats; Receptors, Drug; Theophylline; Vocalization, Animal

1975
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Aug-15, Volume: 88, Issue:16

    Topics: Adenosine; Animals; Apomorphine; Benzazepines; Binding, Competitive; Cell Membrane; Corpus Striatum; Dopamine; Dopamine Agents; Kinetics; Male; Phenethylamines; Phenylisopropyladenosine; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Purinergic; Salicylamides; Theophylline

1991
Methylxanthine-induced attenuation of pecking in chickens.
    British journal of pharmacology, 1991, Volume: 104, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Behavior, Animal; Caffeine; Chickens; Dipyridamole; Female; Male; Theophylline; Xanthines

1991
Striatal A2 receptor regulates apomorphine-induced turning in rats with unilateral dopamine denervation.
    Psychopharmacology, 1991, Volume: 103, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Brain Chemistry; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Oxidopamine; Rats; Receptors, Purinergic; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical; Theophylline

1991
Adenosine A2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine D2 autoreceptor activation.
    European journal of pharmacology, 1990, Aug-28, Volume: 185, Issue:2-3

    Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Apomorphine; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine Agents; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Theophylline; Tyrosine 3-Monooxygenase

1990
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline

1986
Rotational behaviour induced by theophylline in 6-OHDA nigrostriatal denervated rats is dependent on the supersensitivity of striatal dopaminergic receptors.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:3

    Topics: Animals; Apomorphine; Corpus Striatum; Denervation; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Rotation; Substantia Nigra; Theophylline

1989
Interactions of drugs acting on central dopamine receptors and cholinoceptors on yawning responses in the rat induced by apomorphine, bromocriptine or physostigmine.
    British journal of pharmacology, 1989, Volume: 96, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Atropine; Behavior, Animal; Benzazepines; Bromocriptine; Drug Interactions; Male; Physostigmine; Rats; Receptors, Cholinergic; Receptors, Dopamine; Theophylline; Yawning

1989
Different sensitivities of the phosphodiesterases (adenosine-3',5'-cyclic phosphate 3'-phosphohydrolase) of dog cerebral cortex and erythrocytes to inhibition by synthetic agents and cold.
    Biochemical pharmacology, 1971, Volume: 20, Issue:8

    Topics: Animals; Apomorphine; Benzyl Compounds; Cerebral Cortex; Cold Temperature; Cyclic AMP; Dogs; Erythrocytes; Imidazoles; In Vitro Techniques; Ketones; Papaverine; Phenylacetates; Phosphoric Monoester Hydrolases; Rats; Temperature; Theophylline

1971
[Pharmacologic changes in feeding behavior: food intake and rumination in sheep].
    Psychopharmacologia, 1968, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Cerebral Cortex; Chlorpromazine; Digestion; Digitalis Glycosides; Eating; Imipramine; Iproniazid; Lanatosides; Mescaline; Methylphenidate; Morphine; Ouabain; Pentobarbital; Psychopharmacology; Reticulum; Rumen; Sheep; Theophylline

1968
Involvement of adenosine receptor activities in aggressive responses produced by clonidine in mice.
    Psychopharmacology, 1984, Volume: 83, Issue:4

    Topics: Adenosine; Aggression; Animals; Apomorphine; Bicuculline; Clonidine; Diazepam; Dipyridamole; Humans; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1984
On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:3

    Topics: Adenosine; Animals; Apomorphine; Brain; Drug Synergism; Male; Motor Activity; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Rotation; Theophylline; Xanthines

1983
Properties of rotational behaviour produced by methylxanthine derivatives in mice with unilateral striatal 6-hydroxydopamine-induced lesions.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:4

    Topics: Animals; Apomorphine; Corpus Striatum; Humans; Hydroxydopamines; Levodopa; Male; Mice; Receptors, Dopamine; Stereotyped Behavior; Theophylline; Time Factors; Xanthines

1981
Dopamine-independent and adenosine-dependent mechanisms involved in the effects of N-methyl-D-aspartate on motor activity in mice.
    European journal of pharmacology, 1995, Mar-06, Volume: 275, Issue:2

    Topics: Adenosine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Antagonists; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Motor Activity; N-Methylaspartate; Reserpine; Theophylline

1995
Effects of adenosine analogues on apomorphine-induced penile erection in rats.
    General pharmacology, 1995, Volume: 26, Issue:8

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Male; Penile Erection; Rats; Receptors, Purinergic P1; Theophylline

1995
Synthesis and preliminary pharmacological screening of novel imidazo[2,1-f]theophylline derivatives.
    Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:9

    Topics: Amphetamine; Animals; Apomorphine; Central Nervous System Stimulants; Dopamine Agonists; Drug Antagonism; Drug Evaluation, Preclinical; Mice; Motor Activity; Seizures; Structure-Activity Relationship; Theophylline

2002