theophylline and apnea

theophylline has been researched along with apnea in 198 studies

Research

Studies (198)

Timeframe	Studies, this research(%)	All Research%
pre-1990	114 (57.58)	18.7374
1990's	40 (20.20)	18.2507
2000's	26 (13.13)	29.6817
2010's	13 (6.57)	24.3611
2020's	5 (2.53)	2.80

Authors

Authors	Studies
Davi, MJ; Rigatto, H; Sankaran, K; Seshia, MM; Simons, FE; Simons, KJ	1
Andre, M; Boutroy, MJ; Monin, P; Vert, P	1
Aranda, JV; Baltassat, P; Bethenod, M; Bory, C; Frederich, A; Porthault, M	2
Boutroy, MJ; Monin, P; Royer, RJ; Royer-Morrot, MJ; Vert, P	2
Gotay, F; Moylan, FM; Rogers, MC; Shannon, DC; Stein, IM; Todres, ID	1
Rigatto, H	1
Peabody, JL	1
Aranda, JV; Turmen, T	1
Buchanan, N	1
Erkan, NV; Gal, P; Robinson, H; Roop, C	1
Baillie, E; Jones, RA	1
Brazier, JL; Renaud, H; Ribon, B; Salle, BL	1
Heeley, AF; King, DM; Kuzemko, JA	1
Gotay, F; Shannon, DC	1
Bada, HS; Khanna, NN; Somani, SM; Tin, AA	1
Pagani, G; Petrone, M; Raponi, S	1
Aldridge, A; Aranda, JV; Haber, R; Louridas, AT; Thom, P; Vitullo, BB	1
Cartwright, D; DeBuse, P	1
Neese, AL; Soyka, LF	1
Gupta, JM; Mercer, H	1
Hommes, PM; Jarrett, TE; McClain, W; Melchior, JB; Wasserlauf, H	1
Assael, BM; Bonati, M; Caccamo, ML; Gerna, M; Latini, R; Mandelli, M; Marini, A; Sereni, F; Tognoni, G	1
Riechert, M	1
Eisenberg, W; Holzgraefe, E; Naim, M	1
Barr, PA	1
Auld, PA; Dietrich, J; Drayer, DE; Krauss, AN; Reidenberg, M	1
Drayton, MR; Gamsu, HR; Larcher, VF; Sanderson, MC; Sandhu, B	1
Frisch, H; Irnberger, E; Müller, W	1
Hart, BA; Koup, JR	1
Giacoia, G; Jusko, WJ; Koup, JR; Menke, J	1
Light, GS; Nobel, PA	1
Assael, BM; Caccamo, ML; Gerna, M; Latini, R; Mandelli, M; Marini, A; Sereni, F; Tognoni, G	1
Aranda, JV; Loughnan, PM; Neims, AH; Parsons, WD; Sitar, DS	1
Rosenfeld, CR	1
Aranda, JV; Dupont, C	1
Lucey, JF	1
Shapiro, DL; Smith, B; Uauy, R; Warshaw, JB	1
Ashavaid, TF; Merchant, RH; Sakhalkar, VS	1
Hipps, R; Lantos, J; Meadow, W; Mendez, D; Ostrowski, M	1
Johnston, DM; Kuzemko, JA	1
Hsieh, JC; Lee, TY; Lu, PK; Lui, PW	1
Eichenwald, EC; Howell, RG; Kosch, PC; Lindsey, J; Stark, R; Ungarelli, RA	1
Carnevale, A; Chiarotti, M; De Carolis, MP; De Giovanni, N; Muzii, U; Romagnoli, C; Tortorolo, G; Zecca, E	1
Brown, SS; Chin, KC; Durbin, GM; Hale, KA; Morgan, ME; Scanlon, JE	1
Brion, LP; Reinersman, G; Roth, P; Vega-Rich, C	1
Irani, AJ; Merchant, RH	1
Costa, R; Marino, A	1
Belan, MA; Cowen, CP; Mathew, OP; Thoppil, CK	1
Coutts, RT; Finer, NN; Jamali, F; Malek, F; Peliowski, A	1
Milner, AD; Stokes, GM; Upton, CJ	1
Belmont-Gómez, A; Calderón-Mandujano, B; González-Treviño, J; Juárez-Olguín, H; Prado-Serrano, A; Rodríguez-Palomares, C; Udaeta-Mora, E	1
Sacristán del Castillo, JA; Soto Alvarez, J	1
Cates, DB; Hasan, SU; Kwiatkowski, K; Rigatto, H; Seifert, B; Tay-Uyboco, J	1
Finer, NN; Peliowski, A	1
Fuglsang, G; Jakobsen, P; Kjaer Nielsen, L; Nielsen, K; Sennels, F; Thelle, T	1
Pickens, DL; Schefft, GL; Storch, GA; Thach, BT	1
Casasin Edo, T; Closa, RM; Gómez Papi, A; Tarres Roure, A	1
Huseman, CA; Nelson, RM; Varma, MM; Willett, LD	1
Finer, NN; Muttitt, SC; Rossmann, J; Tierney, AJ	1
Congdon, PJ; Faye, S; Hay, AW; Nadkarni, S	1
Finer, NN; Muttitt, SC; Tierney, AJ	1
Ballard, RA; Clyman, RI; Durand, DJ; Goodman, A; Ray, P	1
Davies, AM; Koenig, JS; Thach, BT	1
Brouillette, RT; Hunt, CE	1
Krauss, AN	1
Badonnel, Y; Bairam, A; Boutroy, MJ; Vert, P	1
Frank, M	1
Fox, WW; Spitzer, AR	2
Abbasi, S; Davis, JM; Johnson, L; Spitzer, AR	1
McCulloch, K; Vidyasagar, D	1
Gottschalk, SK; Kissling, GE; Schuth, CR; Tran, TH; Yazdani, M	1
Kusenbach, G; Reinhardt, D	1
Bergman, B; Hedner, J; Hedner, T; Jonason, J; Mueller, RA	1
Cabal, L; Rambhatla, S; Sims, ME; Wu, PY; Yau, G	1
Gal, P; Gilman, JT	1
Lyon, AJ; McIntosh, N	1
Brouard, C; de Gamarra, E; Flouvat, B; Moriette, G; Murat, I; Pajot, N; Relier, JP; Walti, H	1
Koyama, EA; Spierer, DN	1
Funke, LA	1
Bhat, AM; Chuang, L; Karoum, F; Lavenstein, B; Scanlon, JW	2
Banagale, RC; Howatt, WF; Roloff, DW	1
Haley, TJ	1
Coward, JH; Duffley, LM; Finer, NN; Peters, KL	1
Weinberger, M	1
Wennergren, G; Wennergren, M	1
Rogers, Y; Tudehope, DI	1
Aranda, JV; Beharry, K; Papageorgiou, A; Scalais, E	1
Bjure, J; Kjellmer, I; Wennergren, G	1
Bielicki, M; Sourgens, H; Staib, AH; von Loewenich, V	1
Caccamo, ML; Fesslová, V; Marimi, A; Salice, P	1
Jones, RA	1
Broberger, U; Lagercrantz, H; Milerad, J; von Euler, C	1
Lindström, B; Lönnerholm, G; Paalzow, L; Sedin, G	1
Burke, J; Loadsman, T; Tudehope, D	1
Hargreaves, DB; Lealman, GT; Mulley, BA	1
Cattamanchi, G; Pildes, RS; Singh, J; Srinivasan, G; Yeh, TF	1
Alexander, JR; Farndon, PA; Jones, RA; Kong, C; Levitt, GA; Richards, JM; Southall, DP; Wilson, AJ	1
Jaspan, JB; Pildes, RS; Shankar, H; Singh, J; Srinivasan, G; Tiruvury, A; Yeh, TF	1
Nelson, RM; Resnick, MB	1
Kelly, DH; Shannon, DC	2
Horowitz, DA; Jablonski, WJ; Mehta, KA	1
Mathew, OP; Roberts, JL; Thach, BT	1
Bergt, U; Heimann, G; Murgescu, J	1
Boyer, A; Chua, C; Khanna, NN; Menke, JA; Miller, J; Somani, SM	1
Alix, D; Berthou, F; Dreano, Y; Gouedard, H; Picart, D; Riche, C	1
Banagale, RC	1
Bada, HS; Khanna, NN; Somani, SM	2
Aranda, JV; Grondin, D; Sasyniuk, BI	1
King, KC; Takieddine, FN; Tserng, KY	1
Green, TP; Mirkin, BL	1
Baltassat, P; Bethenod, M; Bory, B; Bourgeois, J; Cottancin, G; Frederich, A; Sann, L	1
Auld, PA; Krauss, AN; Milsap, RL	2
Rigatto, H; Simons, FE; Simons, KJ	1
Khanna, NN; Somani, SM	1
Aranda, JV; Clozel, M; Howell, J	1
Assael, BM; Bonati, M; Latini, R; Marra, G; Parini, R	1
Lipowsky, G; Riechert, M; Stiegler, H; Stöckl, H	1
Gupta, JM; Koo, WW; Mercer, HP	1
Auld, PA; Krauss, AN; Milsap, RL; Myers, TF; Reidenberg, MM	1
Anderson, DG; Barr, PA; O'Loughlin, EV	1
Lagercrantz, H; Rane, A; Tunell, R	1
Giacoia, G; Hilligoss, DM; Jusko, WJ; Koup, JR	1
Eitzman, DV; Holstrum, WJ; Nelson, RM; Resnick, MB	1
Floberg, S; Lindström, B; Lönnerholm, G	1
Fozard, JR; Hannon, JP; Pfannkuche, HJ	1
Brendstrup, L; Flachs, H; Larsen, PB; Skov, L	1
Crosson, JE; Dunnigan, A; Etheridge, SP; Hesslein, PS; Milstein, S	1
Ozbag, E	1
Narang, A; Rao, R	1
Hogue, SL; Phelps, SJ	1
Brion, LP; Gonzalez, MT; Schulman, M; Sherwood, JB	1
Gaylord, M; Lorch, V; Miller, CA; Zimmerman, AW	1
Brans, YW; Kazzi, NJ; Morbach, CA	1
Berul, CI	1
Avital, A; Chernick, V; Jansen, AH; Sitar, DS	1
Calhoun, LK	1
Abedin, M; Agwunobi, J; Beeram, M; Sinkford, S; Young, M	1
Charles, BG; Flenady, VJ; Grant, TC; Lee, TC; Steer, PA	1
al-Alaiyan, S; al-Omran, A	1
Lipsky, JJ; Vassallo, R	1
Kotagal, U; Pesce, AJ; Rashkin, M	1
Fang, S; Gamsu, HR; Greenough, A; Marsden, JT; Peters, TJ; Sherwood, RA	1
Hudgel, DW; Thanakitcharu, S	1
Asoh, M; Kobayashi, S; Koitabashi, Y; Okano, YJ; Tateishi, T; Yamaguchi, A; Yoda, T	1
Adhikari, M; Botha, JH; du Preez, MJ; McFadyen, ML	1
Diderholm, B; Ewald, U; Gustafsson, J	1
Callanan, C; Davis, NM; Davis, PG; Doyle, LW; Ford, GW; Kelly, EA; Rickards, AL	1
Henderson-Smart, DJ; Steer, P	4
Henderson-Smart, DJ; Steer, PA	2
Henderson-Smart, DJ; Osborn, DA	1
Davis, PG; Henderson-Smart, DJ; Subramanian, P	1
Ahn, HW; Choi, JH; Park, KJ; Shin, WG; Suh, OK	1
Bhatia, J	1
Hudson-Mason, A; Lemke, RP; Osiovich, H; Sreenan, C	1
Jarrett, RV; Kauffman, RE; Lowry, JA; Pettett, G; Wasserman, G	1
Davis, PG; Henderson-Smart, DJ; Subramaniam, P	1
Barrington, KJ; Rich, W; Tan, K	1
Gannon, BA	1
Bhatt-Mehta, V; Schumacher, RE	1
Rieger-Fackeldey, E; Schulze, A; von Poblotzki, M	1
Wasunna, A	1
Fischer, R; Huber, RM; Lang, SM; Leitl, M; Steiner, U; Thiere, M	1
Ali, AS; Fida, NM; Islam, SI; Sheikh, AA	1
Anderson, BJ; McNamara, DG; Nixon, GM	1
Fukuda, T; Imamura, T; Irie, T; Irikura, M; Kondo, G; Kondo, Y; Maeda, T; Shin-o, T; Yukawa, E	1
Ebisu, R; Hayashi, T; Hayashi, Y; Kubo, S; Minowa, H; Ohgitani, A; Uchida, Y; Yoshida, K; Yoshizawa, H	1
Chereches-Panta, P; Culea, M; Nanulescu, MV; Palibroda, N	1
Hanada, K; Ishikawa, Y; Ito, Y; Kushida, K; Nakamura, T; Ogata, H; Saito, M; Suda, Y; Tsuchiwata, S	1
Al-Saif, S; Alvaro, R; Cates, D; Kwiatkowski, K; Manfreda, J; Qurashi, M; Rigatto, H	1
Bacopoulou, F; Markantonis, SL; Skouroliakou, M	1
De Paoli, AG; Henderson-Smart, DJ	2
Al-Matary, A; Al-Saif, S; Alvaro, RE; Cates, D; Chiu, A; Khalil, M; Kwiatkowski, K; Manfreda, J; Minski, J; Qurashi, M; Rigatto, H	1
Agnetti, A; Barbato, G; Bo, I; Carano, N; Tchana, B; Zanetti, E	1
Schoen, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Yu, T	1
Ballanyi, K; Ciechanski, P; Mosca, EV; Roy, A; Scheibli, EC; Wilson, RJ	1
Pacifici, GM	1
Franco, R; Martínez-Pinilla, E; Oñatibia-Astibia, A	1
Douchi, T; Irie, T; Irikura, M; Ishitsuka, Y; Kondo, T; Kondo, Y; Mitarai, F; Orita, Y; Shimodozono, Y; Takeda, Y	1
Onland, W; Ten Hove, CH; van Kaam, AH; Vliegenthart, RJ	1
Cho, JY; Choi, CW; Kim, BI; Kim, EK; Kim, HS; Lee, J; Lee, JA; Oh, J; Park, EA; Shin, SH; Sohn, JA; Yu, KS	1
Dong, Z; Lu, X; Lyu, Q; Mao, Y; Miao, C; Ye, C; Yu, L; Zhang, J	1
Abushanab, D; Al-Badriyeh, D; Al-Shaibi, S; Alhersh, E	1
Asakai, H; Oda, Y; Sato, A	1
Chen, F; Cheng, R; Dai, HR; Ding, XS; Du, FF; Guo, HL; Hu, YH; Long, JY; Tian, M; Xia, Y; Xu, J	1
Atallah, ÁN; Drager, LF; Lorenzi-Filho, G; Pachito, DV; Pinto, ACPN; Rocha, A	1
Bruschettini, M; Marques, KA; Moresco, L; Sjögren, A; Soll, R	1

Reviews

35 review(s) available for theophylline and apnea

Article	Year
Apnea and periodic breathing. Seminars in perinatology, 1977, Volume: 1, Issue:4 Topics: Apnea; Carbon Dioxide; Cheyne-Stokes Respiration; Humans; Hypoxia; Infant, Newborn; Infant, Premature, Diseases; Periodicity; Respiration; Respiratory Distress Syndrome, Newborn; Respiratory Function Tests; Theophylline	1977
Transcutaneous oxygen measurement to evaluate drug effects. Clinics in perinatology, 1979, Volume: 6, Issue:1 Topics: Anesthesia, Obstetrical; Apnea; Electrodes; Female; Fetal Monitoring; Humans; Infant, Newborn; Infant, Newborn, Diseases; Labor, Obstetric; Monitoring, Physiologic; Oxygen; Pregnancy; Skin; Theophylline	1979
Methylxanthines in apnea of prematurity. Clinics in perinatology, 1979, Volume: 6, Issue:1 Topics: Apnea; Caffeine; Hemodynamics; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Respiration; Theophylline	1979
Clinical pharmacology of theophylline. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jul-14, Volume: 56, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aging; Apnea; Arterioles; Biological Availability; Bronchial Spasm; Child; Diet; Drug Therapy, Combination; Forced Expiratory Volume; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intravenous; Myocardial Contraction; Smoking; Stimulation, Chemical; Theophylline; Tissue Distribution; Veins; Vital Capacity	1979
Pharmacotherapy of neonatal apnea. Indian pediatrics, 1991, Volume: 28, Issue:11 Topics: Apnea; Caffeine; Citrates; Doxapram; Drug Combinations; Humans; Infant, Newborn; Theophylline	1991
[Recent acquisitions on the pharmacology and therapeutic uses of theophylline with special reference to cardiovascular effects]. La Clinica terapeutica, 1991, Feb-28, Volume: 136, Issue:4 Topics: Adult; Angina Pectoris; Apnea; Asthma; Cardiovascular System; Child; Female; Humans; Infant, Newborn; Male; Nervous System; Theophylline	1991
Metabolism and pharmacokinetics of theophylline in human neonates, children, and adults. Drug metabolism reviews, 1983, Volume: 14, Issue:2 Topics: Adult; Age Factors; Apnea; Asthma; Biotransformation; Bradycardia; Caffeine; Child; Female; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Kinetics; Male; Methylation; Pulmonary Edema; Theophylline; Tissue Distribution	1983
The pharmacology and therapeutic use of theophylline. The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 1 Topics: Acute Disease; Adolescent; Adult; Apnea; Asthma; Bronchodilator Agents; Chemistry, Pharmaceutical; Child; Child, Preschool; Drug Stability; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline	1984
SIDS and near-SIDS (second of two parts). The New England journal of medicine, 1982, Apr-29, Volume: 306, Issue:17 Topics: Apnea; Counseling; Family; Humans; Infant; Infections; Monitoring, Physiologic; Respiration; Socioeconomic Factors; Sudden Infant Death; Theophylline	1982
Pharmacologic management of apnea of prematurity. The Journal of perinatal & neonatal nursing, 1996, Volume: 9, Issue:4 Topics: Apnea; Bronchodilator Agents; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1996
Theophylline: recent advances in the understanding of its mode of action and uses in clinical practice. Mayo Clinic proceedings, 1998, Volume: 73, Issue:4 Topics: Apnea; Apoptosis; Asthma; Calcium Channels; Capillary Leak Syndrome; Catecholamines; Erythropoietin; Humans; Immunity; Kidney; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases, Obstructive; Phosphoric Diester Hydrolases; Receptors, Purinergic P1; Theophylline	1998
Standards of laboratory practice: theophylline and caffeine monitoring. National Academy of Clinical Biochemistry. Clinical chemistry, 1998, Volume: 44, Issue:5 Topics: Apnea; Bronchodilator Agents; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Lung Diseases, Obstructive; Quality Control; Specimen Handling; Theophylline	1998
Pharmacologic treatment of sleep-disordered breathing. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:3 Topics: Acetazolamide; Antihypertensive Agents; Apnea; Bronchodilator Agents; Diuretics; Dyspnea; Evidence-Based Medicine; Female; Heart Failure; Humans; Hypercapnia; Hypoventilation; Male; Medroxyprogesterone; Myxedema; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Obesity; Progesterone Congeners; Psychotropic Drugs; Randomized Controlled Trials as Topic; Research Design; Respiratory System Agents; Sleep Apnea Syndromes; Theophylline; Thyroid Hormones	1998
Doxapram versus methylxanthine for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Aminophylline; Apnea; Doxapram; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Respiratory System Agents; Theophylline; Xanthines	2000
Caffeine versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	2000
Kinesthetic stimulation versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Apnea; Beds; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Kinesiology, Applied; Physical Stimulation; Theophylline; Xanthines	2000
Continuous positive airway pressure versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Positive-Pressure Respiration; Theophylline; Vasodilator Agents	2000
Methylxanthine treatment for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Vasodilator Agents; Xanthines	2000
Current options in the management of apnea of prematurity. Clinical pediatrics, 2000, Volume: 39, Issue:6 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Doxapram; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Xanthines	2000
Doxapram versus methylxanthine for apnea in preterm infants. The Cochrane database of systematic reviews, 2000, Issue:4 Topics: Aminophylline; Apnea; Doxapram; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Respiratory System Agents; Theophylline; Xanthines	2000
Methylxanthine treatment for apnea in preterm infants. The Cochrane database of systematic reviews, 2001, Issue:3 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline; Vasodilator Agents; Xanthines	2001
Continuous positive airway pressure versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2001, Issue:4 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Positive-Pressure Respiration; Theophylline; Vasodilator Agents	2001
Theophylline or caffeine: which is best for apnea of prematurity? Neonatal network : NN, 2000, Volume: 19, Issue:8 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Theophylline; Treatment Outcome	2000
Treatment of apnea of prematurity. Paediatric drugs, 2003, Volume: 5, Issue:3 Topics: Aminophylline; Apnea; Caffeine; Clinical Trials as Topic; Doxapram; Humans; Infant, Newborn; Infant, Premature; Respiratory System Agents; Theophylline	2003
Methylxanthines for the treatment of apnea associated with bronchiolitis and anesthesia. Paediatric anaesthesia, 2004, Volume: 14, Issue:7 Topics: Anesthesia, General; Apnea; Bronchiolitis; Caffeine; Clinical Trials as Topic; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Respiratory System Agents; Theophylline	2004
Caffeine versus theophylline for apnea in preterm infants. The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1 Topics: Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Theophylline	2010
Methylxanthine treatment for apnoea in preterm infants. The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intermittent Positive-Pressure Ventilation; Randomized Controlled Trials as Topic; Theophylline; Vasodilator Agents; Xanthines	2010
Prophylactic methylxanthine for prevention of apnoea in preterm infants. The Cochrane database of systematic reviews, 2010, Dec-08, Issue:12 Topics: Apnea; Bradycardia; Caffeine; Central Nervous System Stimulants; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Recurrence; Theophylline; Xanthines	2010
Use of methylxanthine therapies for the treatment and prevention of apnea of prematurity. Paediatric drugs, 2014, Volume: 16, Issue:2 Topics: Apnea; Caffeine; Central Nervous System Stimulants; Citrates; Drug Monitoring; Humans; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Theophylline	2014
Clinical pharmacology of theophylline in preterm infants: effects, metabolism and pharmacokinetics. Current pediatric reviews, 2014, Volume: 10, Issue:4 Topics: Apnea; Brain; Bronchodilator Agents; Humans; Infant, Newborn; Infant, Premature; Kidney; Lung; Saliva; Sleep; Theophylline	2014
The potential of methylxanthine-based therapies in pediatric respiratory tract diseases. Respiratory medicine, 2016, Volume: 112 Topics: Adolescent; Apnea; Asthma; Bronchodilator Agents; Caffeine; Child; Child, Preschool; Cough; Humans; Infant; Infant, Newborn; Infant, Premature; Phosphodiesterase Inhibitors; Theobromine; Theophylline; Xanthines	2016
Doxapram Treatment for Apnea of Prematurity: A Systematic Review. Neonatology, 2017, Volume: 111, Issue:2 Topics: Apnea; Caffeine; Doxapram; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Randomized Controlled Trials as Topic; Respiratory System Agents; Theophylline	2017
Caffeine for the Treatment of Apnea in the Neonatal Intensive Care Unit: A Systematic Overview of Meta-Analyses. Paediatric drugs, 2020, Volume: 22, Issue:4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Randomized Controlled Trials as Topic; Theophylline; Treatment Outcome	2020
Pharmacological treatment for central sleep apnoea in adults. The Cochrane database of systematic reviews, 2023, 02-27, Volume: 2 Topics: Acetazolamide; Adult; Aged; Apnea; Buspirone; Carbonic Anhydrase Inhibitors; Disorders of Excessive Somnolence; Female; Heart Failure; Humans; Hypnotics and Sedatives; Male; Sleep Apnea, Central; Theophylline; Triazolam	2023
Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants. The Cochrane database of systematic reviews, 2023, 10-04, Volume: 10 Topics: Aminophylline; Apnea; Birth Weight; Bronchopulmonary Dysplasia; Caffeine; Hearing Loss; Humans; Infant, Extremely Premature; Infant, Newborn; Randomized Controlled Trials as Topic; Theophylline	2023

Trials

21 trial(s) available for theophylline and apnea

Article	Year
Theophylline pharmacokinetics in premature infants with apnea. The Journal of pediatrics, 1976, Volume: 89, Issue:5 Topics: Apnea; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Male; Theophylline	1976
Prophylactic theophylline infusion for prevention of apnea of prematurity. Indian pediatrics, 1992, Volume: 29, Issue:11 Topics: Aminophylline; Apnea; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Infusions, Intravenous; Prospective Studies; Theophylline	1992
Caffeine or theophylline for neonatal apnoea? Archives of disease in childhood, 1992, Volume: 67, Issue:4 Spec No Topics: Apnea; Caffeine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Infant, Premature; Theophylline; Time Factors; Treatment Outcome	1992
A blinded, randomized, placebo-controlled trial to compare theophylline and doxapram for the treatment of apnea of prematurity. The Journal of pediatrics, 1990, Volume: 116, Issue:4 Topics: Apnea; Doxapram; Drug Combinations; Female; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Placebos; Randomized Controlled Trials as Topic; Single-Blind Method; Theophylline	1990
The effect of caffeine compared with theophylline in the treatment of idiopathic apnea in premature infants. Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:5 Topics: Administration, Oral; Apnea; Bradycardia; Caffeine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant, Newborn; Infant, Premature; Male; Random Allocation; Theophylline	1989
Theophylline treatment in the extubation of infants weighing less than 1,250 grams: a controlled trial. Pediatrics, 1987, Volume: 80, Issue:5 Topics: Apnea; Birth Weight; Body Weight; Clinical Trials as Topic; Humans; Infant, Low Birth Weight; Infant, Newborn; Random Allocation; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Theophylline	1987
Theophylline versus caffeine: comparative effects in treatment of idiopathic apnea in the preterm infant. The Journal of pediatrics, 1987, Volume: 110, Issue:4 Topics: Apnea; Caffeine; Double-Blind Method; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Natriuresis; Random Allocation; Respiration; Theophylline	1987
Limitations of theophylline in the treatment of apnea of prematurity. American journal of diseases of children (1960), 1985, Volume: 139, Issue:6 Topics: Apnea; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Premature, Diseases; Random Allocation; Respiration, Artificial; Theophylline	1985
Comparative efficacy of theophylline and caffeine in the treatment of idiopathic apnea in premature infants. American journal of diseases of children (1960), 1985, Volume: 139, Issue:7 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia; Theophylline	1985
An evaluation of theophylline for idiopathic apnea of infancy. Developmental pharmacology and therapeutics, 1984, Volume: 7, Issue:2 Topics: Apnea; Birth Weight; Clinical Trials as Topic; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Respiration; Sleep; Theophylline	1984
Apnoea of immaturity. 1. A controlled trial of theophylline and face mask continuous positive airways pressure. Archives of disease in childhood, 1982, Volume: 57, Issue:10 Topics: Apnea; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physiologic; Positive-Pressure Respiration; Random Allocation; Theophylline; Time Factors	1982
Aminophylline versus caffeine citrate for apnea and bradycardia prophylaxis in premature neonates. Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:4 Topics: Apnea; Bradycardia; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1995
Erythropoietin levels during theophylline treatment in premature infants. The Journal of pediatrics, 1994, Volume: 124, Issue:1 Topics: Apnea; Erythropoietin; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	1994
Comparison of the effects of theophylline and caffeine on serum erythropoietin concentration in premature infants. European journal of pediatrics, 1998, Volume: 157, Issue:5 Topics: Anemia; Apnea; Caffeine; Erythropoietin; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	1998
High-flow nasal cannulae in the management of apnea of prematurity: a comparison with conventional nasal continuous positive airway pressure. Pediatrics, 2001, Volume: 107, Issue:5 Topics: Apnea; Bradycardia; Bronchodilator Agents; Cross-Over Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intubation; Nasal Cavity; Oxygen Consumption; Positive-Pressure Respiration; Theophylline	2001
Effects of theophylline on the pattern of spontaneous breathing in preterm infants less than 1000 g of birth weight. Early human development, 2003, Volume: 72, Issue:1 Topics: Apnea; Bronchodilator Agents; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Oxygen; Respiration; Respiration, Artificial; Theophylline; Tidal Volume	2003
Theophylline and acetazolamide reduce sleep-disordered breathing at high altitude. The European respiratory journal, 2004, Volume: 23, Issue:1 Topics: Acetazolamide; Administration, Oral; Altitude; Altitude Sickness; Apnea; Autacoids; Blood Gas Analysis; Double-Blind Method; Humans; Male; Oxyhemoglobins; Polysomnography; Pulse; Sleep Apnea Syndromes; Theophylline	2004
Pharmacokinetics of theophylline in preterm neonates during the first month of life. Saudi medical journal, 2004, Volume: 25, Issue:4 Topics: Aminophylline; Apnea; Bronchodilator Agents; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Theophylline	2004
A randomized controlled trial of theophylline versus CO2 inhalation for treating apnea of prematurity. The Journal of pediatrics, 2008, Volume: 153, Issue:4 Topics: Administration, Inhalation; Apnea; Bronchodilator Agents; Carbon Dioxide; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Pilot Projects; Theophylline; Treatment Outcome	2008
Caffeine versus theophylline for apnea of prematurity: a randomised controlled trial. Journal of paediatrics and child health, 2009, Volume: 45, Issue:10 Topics: Apnea; Bronchodilator Agents; Caffeine; Central Nervous System Stimulants; Drug Therapy, Combination; Greece; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Secondary Prevention; Theophylline	2009
CO(2) inhalation as a treatment for apnea of prematurity: a randomized double-blind controlled trial. The Journal of pediatrics, 2012, Volume: 160, Issue:2 Topics: Administration, Inhalation; Apnea; Bronchodilator Agents; Carbon Dioxide; Combined Modality Therapy; Double-Blind Method; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Prospective Studies; Severity of Illness Index; Theophylline; Treatment Outcome	2012

Other Studies

142 other study(ies) available for theophylline and apnea

Article	Year
Physiologic changes induced by theophylline in the treatment of apnea in preterm infants. The Journal of pediatrics, 1978, Volume: 92, Issue:1 Topics: Apnea; Blood; Carbon Dioxide; Female; Functional Residual Capacity; Humans; Hydrogen-Ion Concentration; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Lung Volume Measurements; Male; Manitoba; Oxygen; Partial Pressure; Pulmonary Alveoli; Respiratory System; Theophylline; Tidal Volume; Work of Breathing	1978
Treatment with theophylline in near-miss sudden infant death. Lancet (London, England), 1978, Jun-10, Volume: 1, Issue:8076 Topics: Apnea; Humans; Infant; Male; Sudden Infant Death; Theophylline	1978
Biotransformation of theophylline to caffeine in premature newborn. Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101 Topics: Administration, Oral; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1978
Methylation of theophylline to caffeine in premature infants. Lancet (London, England), 1979, Apr-14, Volume: 1, Issue:8120 Topics: Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Methylation; Theophylline; Xanthines	1979
Prevention of apnea and bradycardia in low-birthweight infants. Pediatrics, 1975, Volume: 55, Issue:5 Topics: Apnea; Birth Weight; Bradycardia; Carbon Dioxide; Female; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infant, Premature, Diseases; Male; Oxygen; Partial Pressure; Theophylline	1975
Weaning very low birthweight infants from mechanical ventilation using intermittent mandatory ventilation and theophylline. Archives of disease in childhood, 1979, Volume: 54, Issue:1 Topics: Apnea; Bradycardia; Humans; Hyaline Membrane Disease; Infant, Low Birth Weight; Infant, Newborn; Respiration, Artificial; Theophylline	1979
Dosage schedule for intravenous aminophylline in apnoea of prematurity, based on pharmacokinetic studies. Archives of disease in childhood, 1979, Volume: 54, Issue:3 Topics: Aminophylline; Apnea; Drug Administration Schedule; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Infusions, Parenteral; Metabolic Clearance Rate; Theophylline	1979
Plasma xanthine levels in low birthweight infants treated or not treated with theophylline. Archives of disease in childhood, 1979, Volume: 54, Issue:3 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Milk, Human; Theophylline; Xanthines	1979
Half life of theophylline in the preterm baby with apnoeic attacks. Archives of disease in childhood, 1979, Volume: 54, Issue:3 Topics: Apnea; Half-Life; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1979
Effects of theophylline on serum and urine electrolytes in preterm infants with apnea. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Apnea; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Theophylline; Water-Electrolyte Balance	1979
Metabolism of theophylline to caffeine in premature newborn infants. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Adult; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1979
Interconversion of theophylline and caffeine in newborn infants. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Age Factors; Apnea; Biotransformation; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theobromine; Theophylline; Xanthines	1979
Caffeine, a metabolite of theophylline during the treatment of apnea in the premature infant. The Journal of pediatrics, 1979, Volume: 94, Issue:6 Topics: Apnea; Caffeine; Half-Life; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline	1979
[Treatment of apnea crisis in premature infants with a loading dose of theophylline]. Minerva pediatrica, 1979, Jan-31, Volume: 31, Issue:2 Topics: Apnea; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Injections, Intravenous; Male; Theophylline	1979
Metabolism of theophylline to caffeine in human fetal liver. Science (New York, N.Y.), 1979, Dec-14, Volume: 206, Issue:4424 Topics: Apnea; Biotransformation; Caffeine; Cells, Cultured; Gestational Age; Humans; Infant, Newborn; Liver; Methylation; Theophylline	1979
Respiratory syncytial virus with apnoea treated with theophylline. The Medical journal of Australia, 1979, Sep-22, Volume: 2, Issue:6 Topics: Apnea; Female; Humans; Infant; Nasopharyngitis; Pharyngitis; Respiratory Syncytial Viruses; Respirovirus Infections; Theophylline	1979
Development of a radioimmunoassay for theophylline. Application to studies in premature infants. Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:5 Topics: Aminophylline; Animals; Antibody Specificity; Apnea; Binding, Competitive; Cross Reactions; Goats; Humans; Infant, Newborn; Infant, Premature, Diseases; Methods; Radioimmunoassay; Theophylline; Time Factors	1977
Theophylline and apnoeas of prematurity. The Medical journal of Australia, 1977, Nov-26, Volume: 2, Issue:22 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1977
A micromethod for the determination of serum theophylline. The Journal of the American Osteopathic Association, 1978, Volume: 77, Issue:10 Topics: Apnea; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methods; Theophylline	1978
Kinetics and efficacy of theophylline in the treatment of apnea in the premature newborn. European journal of clinical pharmacology, 1978, May-31, Volume: 13, Issue:3 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline	1978
Micro-method for the determination of caffeine and theophylline allowing direct application of biological fluids to thin-layer chromatography plates. Journal of chromatography, 1978, Jul-01, Volume: 146, Issue:1 Topics: Apnea; Caffeine; Child; Child, Preschool; Chromatography, Thin Layer; Female; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Microchemistry; Saliva; Theophylline	1978
[Theophylline for prevention of apnea in premature infants (author's transl)]. Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:8 Topics: Apnea; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia; Theophylline; Vomiting	1978
Weaning very low birthweight infants from mechanical ventilation using intermittent mandatory ventilation and theophylline. Archives of disease in childhood, 1978, Volume: 53, Issue:7 Topics: Apnea; Carbon Dioxide; Humans; Hyaline Membrane Disease; Infant, Low Birth Weight; Infant, Newborn; Respiration, Artificial; Theophylline; Time Factors	1978
Alterations in state in apneic pre-term infants receiving theophylline. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:4 Topics: Aminophylline; Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Sleep; Sleep Stages; Theophylline	1978
Theophylline toxicity in a neonate. Archives of disease in childhood, 1978, Volume: 53, Issue:9 Topics: Apnea; Diseases in Twins; Glycosuria; Humans; Hyperglycemia; Infant, Newborn; Infant, Newborn, Diseases; Male; Theophylline	1978
[Prevention of neonatal apnea with theophylline (author's transl)]. Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:11 Topics: Apnea; Bradycardia; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Tachycardia; Theophylline	1978
Relationship between plasma and whole blood theophylline concentration in neonates. The Journal of pediatrics, 1979, Volume: 94, Issue:2 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Plasma; Theophylline	1979
Theophylline-induced diuresis in the neonate. The Journal of pediatrics, 1977, Volume: 90, Issue:5 Topics: Apnea; Dehydration; Diuresis; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Polyuria; Theophylline	1977
Effect of exchange transfusion on elimination of theophylline in premature neonates. The Journal of pediatrics, 1977, Volume: 91, Issue:2 Topics: Aminophylline; Apnea; Birth Weight; Dose-Response Relationship, Drug; Exchange Transfusion, Whole Blood; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1977
Pharmacokinetic aspects of theophylline in premature newborns. The New England journal of medicine, 1976, Aug-19, Volume: 295, Issue:8 Topics: Adult; Apnea; Blood Proteins; Child; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Protein Binding; Theophylline; Time Factors	1976
Letter: Questions on theophylline. Pediatrics, 1976, Volume: 58, Issue:3 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1976
Metabolic effect of theophylline in the premature neonate. The Journal of pediatrics, 1976, Volume: 89, Issue:5 Topics: Apnea; Blood Glucose; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1976
The xanthine treatment of apnea of prematurity. Pediatrics, 1975, Volume: 55, Issue:5 Topics: Aminophylline; Apnea; Bradycardia; Caffeine; Humans; Hypoxia; Infant, Newborn; Infant, Premature, Diseases; Prognosis; Theophylline; Xanthines	1975
Treatment of severe apnea in prematures with orally administered theophylline. Pediatrics, 1975, Volume: 55, Issue:5 Topics: Administration, Oral; Apnea; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Recurrence; Respiration, Artificial; Theophylline	1975
What is the legal 'standard of medical care' when there is no standard medical care? A survey of the use of home apnea monitoring by neonatology fellowship training programs in the United States. Pediatrics, 1992, Volume: 89, Issue:6 Pt 1 Topics: Aftercare; Apnea; Attitude of Health Personnel; Delivery of Health Care; Home Nursing; Humans; Infant; Intensive Care Units, Neonatal; Jurisprudence; Monitoring, Physiologic; Neonatology; Nurses; Theophylline; United States	1992
Virus-induced apnoea and theophylline. Lancet (London, England), 1992, Nov-28, Volume: 340, Issue:8831 Topics: Apnea; Humans; Infant; Infant, Newborn; Male; Respiratory Syncytial Viruses; Respirovirus Infections; Theophylline	1992
Post-operative muscle rigidity in an infant. European journal of anaesthesiology, 1992, Volume: 9, Issue:5 Topics: Anesthesia, Intravenous; Apnea; Drug Interactions; Fentanyl; Humans; Hydrocephalus; Infant; Male; Muscle Rigidity; Postoperative Complications; Theophylline; Ventriculoperitoneal Shunt	1992
Developmental changes in sequential activation of laryngeal abductor muscle and diaphragm in infants. Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:4 Topics: Apnea; Diaphragm; Electromyography; Humans; Infant, Newborn; Infant, Premature; Laryngeal Muscles; Muscle Development; Respiratory Mechanics; Respiratory Muscles; Sleep; Theophylline	1992
Effectiveness and side effects of two different doses of caffeine in preventing apnea in premature infants. Therapeutic drug monitoring, 1992, Volume: 14, Issue:1 Topics: Apnea; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Theobromine; Theophylline	1992
Low-dose doxapram for apnea unresponsive to aminophylline in very low birthweight infants. Journal of perinatology : official journal of the California Perinatal Association, 1991, Volume: 11, Issue:4 Topics: Aminophylline; Apnea; Benzyl Alcohol; Benzyl Alcohols; Dose-Response Relationship, Drug; Doxapram; Drug Synergism; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Pilot Projects; Positive-Pressure Respiration; Theophylline; Ventilator Weaning	1991
Behavioral arousal in newborn infants and its association with termination of apnea. Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 70, Issue:6 Topics: Airway Obstruction; Apnea; Arousal; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, Premature; Theophylline	1991
Lack of a pharmacokinetic interaction between doxapram and theophylline in apnea of prematurity. Developmental pharmacology and therapeutics, 1991, Volume: 16, Issue:2 Topics: Apnea; Body Weight; Doxapram; Drug Interactions; Female; Gestational Age; Half-Life; Humans; Infant, Newborn; Infant, Premature; Male; Theophylline	1991
Apnoea, bradycardia, and oxygen saturation in preterm infants. Archives of disease in childhood, 1991, Volume: 66, Issue:4 Spec No Topics: Apnea; Bradycardia; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Longitudinal Studies; Male; Monitoring, Physiologic; Oximetry; Oxygen; Partial Pressure; Theophylline; Time Factors	1991
[Post-dosage loading concentrations of theophylline and pharmacokinetic study after the fifth maintenance dosage in premature newborns with apnea]. Boletin medico del Hospital Infantil de Mexico, 1991, Volume: 48, Issue:3 Topics: Administration, Oral; Apnea; Drug Administration Schedule; Half-Life; Humans; Infant, Newborn; Infant, Premature, Diseases; Injections, Intravenous; Theophylline	1991
[Importance of monitoring theophylline and caffeine plasma levels in the management of neonatal apnea]. Anales espanoles de pediatria, 1991, Volume: 34, Issue:4 Topics: Apnea; Asphyxia Neonatorum; Caffeine; Humans; Infant, Newborn; Monitoring, Physiologic; Theophylline	1991
Clinical and physiological responses to prolonged nasogastric administration of doxapram for apnea of prematurity. Biology of the neonate, 1991, Volume: 59, Issue:4 Topics: Apnea; Doxapram; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Intubation, Gastrointestinal; Male; Respiratory Function Tests; Theophylline	1991
Characterization of prolonged apneic episodes associated with respiratory syncytial virus infection. Pediatric pulmonology, 1989, Volume: 6, Issue:3 Topics: Apnea; Female; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Respiration; Respiratory Syncytial Viruses; Respirovirus Infections; Theophylline	1989
[Monitoring theophylline in premature newborn infants]. Anales espanoles de pediatria, 1989, Volume: 30, Issue:4 Topics: Apnea; Asphyxia Neonatorum; Humans; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physiologic; Theophylline	1989
Theophylline treatment in the neonate with apnea: effect on growth hormone, thyroid hormone and TRH induced TSH secretion. Developmental pharmacology and therapeutics, 1987, Volume: 10, Issue:2 Topics: Apnea; Growth Hormone; Humans; Infant, Newborn; Theophylline; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine	1987
Neonatal apnea: diagnosis by nurse versus computer. Pediatrics, 1988, Volume: 82, Issue:5 Topics: Apnea; Computers; Heart Rate; Humans; Infant, Newborn; Monitoring, Physiologic; Nursing Assessment; Nursing Diagnosis; Sleep Apnea Syndromes; Theophylline	1988
The relationship between theophylline, caffeine and heart rate in neonates. Annals of clinical biochemistry, 1988, Volume: 25 ( Pt 4) Topics: Aminophylline; Apnea; Caffeine; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Theophylline; Xanthines	1988
The dose response of theophylline in the treatment of apnea of prematurity. The Journal of pediatrics, 1988, Volume: 112, Issue:1 Topics: Apnea; Drug Administration Schedule; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Positive-Pressure Respiration; Prospective Studies; Respiration, Artificial; Theophylline; Tidal Volume	1988
Upper airway chemoreflex responses to saline and water in preterm infants. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:4 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature; Larynx; Reflex; Sodium Chloride; Theophylline; Water	1988
Methylxanthine treatment in infants at risk for sudden infant death syndrome. Annals of the New York Academy of Sciences, 1988, Volume: 533 Topics: Apnea; Follow-Up Studies; Home Care Services; Humans; Infant; Infant, Newborn; Monitoring, Physiologic; Respiration; Retrospective Studies; Risk Factors; Sudden Infant Death; Theophylline	1988
Apnea in infancy: pathophysiology, diagnosis, and treatment. New York state journal of medicine, 1986, Volume: 86, Issue:2 Topics: Aminophylline; Apnea; Caffeine; Chemoreceptor Cells; Home Nursing; Humans; Infant; Infant, Newborn; Monitoring, Physiologic; Pulmonary Gas Exchange; Sudden Infant Death; Theophylline	1986
Theophylline: a closer look. Neonatal network : NN, 1987, Volume: 6, Issue:2 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1987
Infant apnea. Pediatric clinics of North America, 1986, Volume: 33, Issue:3 Topics: Airway Obstruction; Apnea; Bradycardia; Caffeine; Cardiography, Impedance; Home Nursing; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physiologic; Risk; Sleep; Sudden Infant Death; Theophylline; Xanthines	1986
Role of theophylline in pathogenesis of necrotizing enterocolitis. The Journal of pediatrics, 1986, Volume: 109, Issue:2 Topics: Apgar Score; Apnea; Birth Weight; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Respiratory Distress Syndrome, Newborn; Risk; Theophylline	1986
Infantile apnea. American family physician, 1986, Volume: 34, Issue:3 Topics: Apnea; Breast Feeding; Diagnosis, Differential; Gastroesophageal Reflux; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Monitoring, Physiologic; Seizures; Sleep Apnea Syndromes; Theophylline	1986
Phenobarbital increases the theophylline requirement of premature infants being treated for apnea. American journal of diseases of children (1960), 1987, Volume: 141, Issue:1 Topics: Apnea; Cerebral Hemorrhage; Drug Interactions; Humans; Infant, Newborn; Infant, Premature; Phenobarbital; Seizures; Theophylline	1987
[Peculiarities of drug therapy in childhood]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:11 Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; Drug Therapy; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Receptors, Drug; Theophylline; Tissue Distribution	1986
Characterization of adenosine-induced respiratory depression in the preterm rabbit. Biology of the neonate, 1985, Volume: 47, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Apnea; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylisopropyladenosine; Rabbits; Respiration Disorders; Theophylline; Tidal Volume; Time Factors	1985
Concerns about the Food and Drug Administration guidelines for neonatal theophylline dosing. Therapeutic drug monitoring, 1986, Volume: 8, Issue:1 Topics: Apnea; Heart Rate; Humans; Infant, Newborn; Theophylline; United States; United States Food and Drug Administration	1986
Rectal aminophylline in the management of apnoea of prematurity. Archives of disease in childhood, 1985, Volume: 60, Issue:1 Topics: Aminophylline; Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Recurrence; Suppositories; Theophylline	1985
Caffeine citrate: an alternative to theophylline for apnea in prematurity. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:10 Topics: Apnea; Caffeine; Citrates; Drug Combinations; Humans; Infant, Newborn; Theophylline	1985
[Shortening of suxamethonium-induced apnea by Akrinor]. Der Anaesthesist, 1968, Volume: 17, Issue:11 Topics: Adolescent; Adult; Anesthesia, Endotracheal; Apnea; Appendectomy; Blood Pressure; Female; Humans; Injections, Intravenous; Male; Pulse; Respiration; Succinylcholine; Theophylline	1968
Effect of theophylline on neurotransmitters in preterm infants with apnea. Clinical neuropharmacology, 1983, Volume: 6, Issue:1 Topics: Apnea; Biogenic Amines; Catecholamines; Homovanillic Acid; Humans; Infant, Newborn; Infant, Premature, Diseases; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Theophylline; Vanilmandelic Acid	1983
Apnea in newborn infants: approach to management. Resuscitation, 1984, Volume: 11, Issue:1-2 Topics: Apnea; Electrocardiography; Home Nursing; Humans; Infant, Newborn; Infant, Newborn, Diseases; Monitoring, Physiologic; Respiratory Function Tests; Risk; Sleep; Sudden Infant Death; Theophylline	1984
Neonatal breathing control mediated via the central chemoreceptors. Acta physiologica Scandinavica, 1983, Volume: 119, Issue:2 Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Cerebrospinal Fluid; Chemoreceptor Cells; Guinea Pigs; Hydrogen-Ion Concentration; Injections, Intravenous; Injections, Intraventricular; Meperidine; Oxygen; Rabbits; Respiration; Theophylline	1983
Clinical spectrum of neonatal apnoea in very low birthweight infants. Australian paediatric journal, 1984, Volume: 20, Issue:2 Topics: Apnea; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Male; Respiration, Artificial; Risk; Theophylline	1984
Ontogeny of human caffeine and theophylline metabolism. Developmental pharmacology and therapeutics, 1984, Volume: 7 Suppl 1 Topics: Adult; Aged; Apnea; Caffeine; Child; Child, Preschool; Half-Life; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Kinetics; Middle Aged; Theophylline	1984
A case of near-miss SIDS developing an abnormal respiratory reaction to hypoxia. Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:5 Topics: Apnea; Humans; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Male; Monitoring, Physiologic; Partial Pressure; Respiration; Risk; Sudden Infant Death; Theophylline	1983
T4 levels in methylxanthine-treated premature newborns. Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Retrospective Studies; Theophylline; Thyroid Gland; Thyrotropin; Thyroxine	1983
Infant apnea. An approach to management. Clinical pediatrics, 1984, Volume: 23, Issue:7 Topics: Apnea; Home Nursing; Humans; Infant; Infant, Newborn; Monitoring, Physiologic; Risk; Sudden Infant Death; Theophylline	1984
Assessment of cardiovascular effects to theophylline in premature newborns by means of serial echocardiography. Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:3 Topics: Apnea; Echocardiography; Hemodynamics; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1984
Ventilatory studies in two older infants with prolonged apnea. Acta paediatrica Scandinavica, 1980, Volume: 69, Issue:4 Topics: Apnea; Carbon Dioxide; Female; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Oxygen; Partial Pressure; Plethysmography, Impedance; Respiration; Sleep Apnea Syndromes; Theophylline	1980
Cerebrospinal fluid concentration of biogenic amine metabolites in idiopathic apnea of prematurity. Biology of the neonate, 1983, Volume: 43, Issue:1-2 Topics: Apnea; Glycols; Homovanillic Acid; Humans; Infant, Newborn; Infant, Premature, Diseases; Methoxyhydroxyphenylglycol; Phenylacetates; Theophylline	1983
Plasma theophylline and caffeine and plasma clearance of theophylline during theophylline treatment in the first year of life. European journal of clinical pharmacology, 1983, Volume: 24, Issue:3 Topics: Apnea; Caffeine; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline; Xanthines	1983
Syndrome of inappropriate antidiuretic hormone (SIADH) secretion in a preterm infant who was receiving oral theophylline. Australian paediatric journal, 1983, Volume: 19, Issue:1 Topics: Administration, Oral; Apnea; Female; Humans; Inappropriate ADH Syndrome; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1983
Plasma xanthine levels in premature infants treated for apnoea with theophylline. Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:2 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline; Xanthines	1983
Plasma glucose changes in preterm infants during oral theophylline therapy. The Journal of pediatrics, 1983, Volume: 103, Issue:3 Topics: Apnea; Blood Glucose; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1983
Undetected episodes of prolonged apnea and severe bradycardia in preterm infants. Pediatrics, 1983, Volume: 72, Issue:4 Topics: Aminophylline; Apnea; Bradycardia; Electrocardiography; Female; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Male; Monitoring, Physiologic; Respiration; Theophylline	1983
Metabolic effects of theophylline in preterm infants. The Journal of pediatrics, 1981, Volume: 98, Issue:5 Topics: Apnea; Blood Glucose; Female; Glucagon; Humans; Infant, Newborn; Infant, Premature; Insulin; Male; Theophylline	1981
Long-term outcome of premature infants treated with theophylline. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Child Development; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Intermittent Positive-Pressure Ventilation; Male; Theophylline	1981
Apnea associated with theophylline withdrawal in a term neonate. American journal of diseases of children (1960), 1982, Volume: 136, Issue:1 Topics: Apnea; Caffeine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pregnancy; Substance Withdrawal Syndrome; Theophylline	1982
The efficacy of theophylline in premature infants with mixed and obstructive apnea and apnea associated with pulmonary and neurologic disease. The Journal of pediatrics, 1982, Volume: 100, Issue:6 Topics: Airway Obstruction; Apnea; Cerebral Hemorrhage; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1982
Influence of food intake on bioavailability of theophylline in premature infants. European journal of clinical pharmacology, 1982, Volume: 22, Issue:2 Topics: Apnea; Biological Availability; Food; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intestinal Absorption; Kinetics; Theophylline	1982
Cross validation of serum to saliva relationships of caffeine, theophylline and total methylxanthines in neonates. Developmental pharmacology and therapeutics, 1982, Volume: 4, Issue:1-2 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Saliva; Theophylline; Xanthines	1982
[Use of caffeine in the treatment of apnea in premature infants]. Developmental pharmacology and therapeutics, 1982, Volume: 4 Suppl Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline; Time Factors	1982
Effect of serum caffeine level on pneumocardiogram of premature infants treated for apnea with theophylline. Medical hypotheses, 1982, Volume: 9, Issue:6 Topics: Apnea; Caffeine; Electrocardiography; False Negative Reactions; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Respiration; Theophylline	1982
Caffeine and theophylline: serum/CSF correlation in premature infants. The Journal of pediatrics, 1980, Volume: 96, Issue:6 Topics: Apnea; Blood-Brain Barrier; Caffeine; Chromatography, Liquid; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline; Xanthines	1980
Pharmacologic considerations in the therapy of neonatal apnea. Pediatric clinics of North America, 1981, Volume: 28, Issue:1 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Monitoring, Physiologic; Theophylline	1981
Theophylline metabolism in premature infants. Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:5 Topics: Aminophylline; Apnea; Biotransformation; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	1981
A method for the bedside application of first-order pharmacokinetics in therapeutic management. Therapeutic drug monitoring, 1980, Volume: 2, Issue:4 Topics: Adult; Apnea; Computers; Drug Therapy; Gentamicins; Humans; Infant, Newborn; Infant, Premature; Kinetics; Models, Biological; Pharmaceutical Preparations; Theophylline	1980
[Apnea and theophylline in the premature infant. Clinical and pharmacokinetic study in 32 premature infants]. Pediatrie, 1981, Volume: 36, Issue:2 Topics: Apnea; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Theophylline	1981
Treatment of apnea and excessive periodic breathing in the full-term infant. Pediatrics, 1981, Volume: 68, Issue:2 Topics: Apnea; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Sleep Apnea Syndromes; Theophylline	1981
Efficacy of low-dose theophylline. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Bradycardia; Heart Rate; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Sleep, REM; Theophylline	1981
Pharmacokinetics of theophylline in neonates. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kinetics; Theophylline	1981
Methylxanthines in serum, saliva, and spinal fluid of premature infants. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kinetics; Saliva; Theophylline	1981
Adverse effects of caffeine and theophylline in the newborn infant. Seminars in perinatology, 1981, Volume: 5, Issue:4 Topics: Apnea; Asphyxia Neonatorum; Caffeine; Cardiovascular System; Central Nervous System; Digestive System; Hormones; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kidney; Retina; Theophylline	1981
Theophylline distribution in the premature neonate. Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:2 Topics: Aging; Animals; Animals, Newborn; Apnea; Blood-Brain Barrier; Female; Gestational Age; Guinea Pigs; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Male; Rats; Species Specificity; Theophylline	1981
[Pharmacokinetics of theophylline and caffeine in premature infants with apnea (author's transl)]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:12 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Protein Binding; Theophylline	1981
Theophylline in treatment of apnoea of prematurity. Australian paediatric journal, 1981, Volume: 17, Issue:4 Topics: Apnea; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1981
Low-dose theophylline therapy in idiopathic apnea of prematurity. The Journal of pediatrics, 1980, Volume: 96, Issue:1 Topics: Apnea; Bradycardia; Carbon Dioxide; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Male; Respiration; Theophylline	1980
Use of salivary concentrations in the prediction of serum caffeine and theophylline concentrations in premature infants. The Journal of pediatrics, 1980, Volume: 96, Issue:3 Pt 1 Topics: Apnea; Caffeine; Humans; Infant, Newborn; Infant, Premature, Diseases; Regression Analysis; Saliva; Theophylline	1980
Bacterial infection in preterm infants during xanthine therapy for idiopathic apnoea of prematurity. Australian paediatric journal, 1980, Volume: 16, Issue:1 Topics: Aminophylline; Apnea; Bacterial Infections; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Theophylline	1980
Plasma concentration-effect relationship of theophylline in treatment of apnea in preterm infants. European journal of clinical pharmacology, 1980, Volume: 18, Issue:1 Topics: Apnea; Gestational Age; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Respiration; Theophylline; Time Factors	1980
Oxygen consumption in apneic premature infants after low-dose theophylline. Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:4 Topics: Apnea; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Oxygen Consumption; Theophylline	1980
Factors affecting theophylline pharmacokinetics in premature infants with apnea. Developmental pharmacology and therapeutics, 1980, Volume: 1, Issue:1 Topics: Age Factors; Apnea; Body Weight; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Kinetics; Male; Metabolic Clearance Rate; Regression Analysis; Theophylline	1980
Developmental outcome of premature infants treated with theophylline. Developmental pharmacology and therapeutics, 1980, Volume: 1, Issue:5 Topics: Apnea; Growth; Humans; Infant, Newborn; Infant, Premature, Diseases; Theophylline	1980
Simultaneous determination of theophylline and caffeine after extractive alkylation in small volumes of plasma by gas chromatography--mass spectrometry. Journal of chromatography, 1980, Nov-14, Volume: 221, Issue:1 Topics: Alkylation; Apnea; Caffeine; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Theophylline	1980
A role for mast cells in adenosine A3 receptor-mediated hypotension in the rat. British journal of pharmacology, 1995, Volume: 115, Issue:6 Topics: Adenosine; Animals; Antihypertensive Agents; Apnea; Cromolyn Sodium; Dose-Response Relationship, Drug; Hypotension; Injections, Intravenous; Male; Mast Cells; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Theophylline	1995
Therapeutic and diagnostic utility of adenosine during tachycardia evaluation in children. The American journal of cardiology, 1994, Jul-15, Volume: 74, Issue:2 Topics: Adenosine; Adolescent; Adult; Apnea; Arrhythmia, Sinus; Atrial Fibrillation; Atrial Function; Atrioventricular Node; Bradycardia; Child; Child, Preschool; Drug Interactions; Electrocardiography; Electrophysiology; Heart Block; Humans; Infant; Infant, Newborn; Injections, Intravenous; Tachycardia; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Ventricular; Theophylline	1994
The use of primidone in neonates with theophylline-resistant apnea. Archives of pediatrics & adolescent medicine, 1994, Volume: 148, Issue:3 Topics: Apnea; Drug Resistance; Humans; Infant, Newborn; Primidone; Theophylline	1994
Theophylline infusion for prevention of apnea of prematurity. Indian pediatrics, 1993, Volume: 30, Issue:6 Topics: Apnea; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature, Diseases; Infusions, Intravenous; Theophylline	1993
Evaluation of three theophylline dosing equations for use in infants up to one year of age. The Journal of pediatrics, 1993, Volume: 123, Issue:4 Topics: Apnea; Asthma; Bradycardia; Dose-Response Relationship, Drug; Female; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Theophylline	1993
The use of primidone in neonates with theophylline-resistant apnea. American journal of diseases of children (1960), 1993, Volume: 147, Issue:2 Topics: Apnea; Bradycardia; Drug Resistance; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Primidone; Retrospective Studies; Theophylline	1993
Effects of theophylline on plasma lipids in low-birth-weight infants (< or = 1250 g). Acta paediatrica (Oslo, Norway : 1992), 1993, Volume: 82, Issue:1 Topics: Apnea; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Lipids; Male; Theophylline; Triglycerides	1993
Higher adenosine dosage required for supraventricular tachycardia in infants treated with theophylline. Clinical pediatrics, 1993, Volume: 32, Issue:3 Topics: Adenosine; Apnea; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Theophylline	1993
Influence of prolonged adenosine receptor blockade on fetal sleep and breathing patterns. Respiration physiology, 1993, Volume: 91, Issue:2-3 Topics: Animals; Apnea; Female; Fetus; Infusions, Intravenous; Phenylisopropyladenosine; Pregnancy; Purinergic Antagonists; Receptors, Purinergic; Respiration; Sheep; Sleep; Sleep, REM; Theophylline; Xanthines	1993
Impact of theophylline use in Wolff-Parkinson-White syndrome. Journal of the National Medical Association, 1996, Volume: 88, Issue:7 Topics: Aminophylline; Apnea; Bronchodilator Agents; Cardiotonic Agents; Electrocardiography; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Respiratory Distress Syndrome, Newborn; Theophylline; Wolff-Parkinson-White Syndrome	1996
Theophylline population pharmacokinetics from routine monitoring data in very premature infants with apnoea. British journal of clinical pharmacology, 1996, Volume: 41, Issue:3 Topics: Apnea; Humans; Infant; Infant, Newborn; Retrospective Studies; Theophylline; Time Factors	1996
Theophylline concentration following equal doses of intravenous aminophylline and oral theophylline in preterm infants. American journal of perinatology, 1997, Volume: 14, Issue:3 Topics: Administration, Oral; Aminophylline; Apnea; Birth Weight; Bronchodilator Agents; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Injections, Intravenous; Theophylline	1997
Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients. Pediatric research, 1999, Volume: 45, Issue:1 Topics: Aging; Apnea; Asthma; Child, Preschool; Cytochrome P-450 CYP1A2; Humans; Infant; Infant, Newborn; Theophylline; Uric Acid; Xanthines	1999
The effect of theophylline on apnoea and hypoxaemic episodes in the premature neonate during the 1st 3 days after birth. Annals of tropical paediatrics, 1998, Volume: 18, Issue:3 Topics: Apnea; Blood Pressure; Bradycardia; Bronchodilator Agents; Caffeine; Female; Gestational Age; Humans; Hypoxia; Infant, Newborn; Infant, Small for Gestational Age; Male; Oxygen; Theophylline	1998
Effect of theophylline on glucose production and lipolysis in preterm infants (< or = 32 weeks). Pediatric research, 1999, Volume: 45, Issue:5 Pt 1 Topics: Apnea; Blood Glucose; Bronchodilator Agents; Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Gestational Age; Gluconeogenesis; Glucose; Glycerol; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Lipolysis; Liver; Regression Analysis; Theophylline	1999
Methylxanthines and sensorineural outcome at 14 years in children < 1501 g birthweight. Journal of paediatrics and child health, 2000, Volume: 36, Issue:1 Topics: Adolescent; Apnea; Bronchodilator Agents; Cerebral Palsy; Child Development; Developmental Disabilities; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Psychological Tests; Survivors; Theophylline	2000
Pharmacokinetics of theophylline and caffeine after intravenous administration of aminophylline to premature neonates in Korea. Research communications in molecular pathology and pharmacology, 1999, Volume: 105, Issue:1-2 Topics: Aminophylline; Apnea; Caffeine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Korea; Male; Theophylline	1999
Theophylline toxicokinetics in premature newborns. Archives of pediatrics & adolescent medicine, 2001, Volume: 155, Issue:8 Topics: Apnea; Bronchodilator Agents; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature, Diseases; Infusions, Intravenous; Intensive Care Units, Neonatal; Male; Respiratory Distress Syndrome, Newborn; Risk Assessment; Tachycardia, Sinus; Theophylline	2001
Apnea at discharge and gastro-esophageal reflux in the preterm infant. Journal of perinatology : official journal of the California Perinatal Association, 2002, Volume: 22, Issue:1 Topics: Apnea; Bronchodilator Agents; Gastroesophageal Reflux; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Theophylline	2002
Effects of theophylline administration and intracranial abnormalities on protective head turning response in preterm infants. East African medical journal, 2003, Volume: 80, Issue:4 Topics: Apnea; Brain; Bronchodilator Agents; Child Development; Echoencephalography; Female; Follow-Up Studies; Head; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Movement; Theophylline; Time Factors	2003
Population pharmacokinetics of theophylline in very premature Japanese infants with apnoea. Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:6 Topics: Apnea; Asian People; Bronchodilator Agents; Female; Humans; Infant, Newborn; Infant, Premature; Male; Models, Biological; Reproducibility of Results; Retrospective Studies; Theophylline	2005
Respiratory inhibition after crying in infants. Pediatrics international : official journal of the Japan Pediatric Society, 2006, Volume: 48, Issue:6 Topics: Apnea; Brain Diseases; Bronchodilator Agents; Case-Control Studies; Crying; Cysts; Female; Head; Humans; Infant; Male; Mass Screening; Oximetry; Oxygen; Polysomnography; Prognosis; Prospective Studies; Respiration; Theophylline; Treatment Outcome; Ultrasonography	2006
Reliability of salivary theophylline in monitoring the treatment for apnoea of prematurity. Journal of perinatology : official journal of the California Perinatal Association, 2007, Volume: 27, Issue:11 Topics: Aminophylline; Apnea; Bronchodilator Agents; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Respiratory Distress Syndrome, Newborn; Saliva; Sensitivity and Specificity; Statistics as Topic; Theophylline	2007
[Population pharmacokinetic analysis of two theophylline formulations in premature neonates and infants with apnea]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:4 Topics: Administration, Oral; Apnea; Bronchodilator Agents; Chemistry, Pharmaceutical; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Models, Biological; Theophylline	2008
Glycopyrrolate and theophylline for the treatment of severe pallid breath-holding spells. Pediatrics, 2013, Volume: 131, Issue:4 Topics: Apnea; Breath Holding; Female; Glycopyrrolate; Humans; Infant; Muscarinic Antagonists; Phosphodiesterase Inhibitors; Recurrence; Seizures; Syncope; Theophylline	2013
Methylxanthine reversal of opioid-induced respiratory depression in the neonatal rat: mechanism and location of action. Respiratory physiology & neurobiology, 2014, Aug-15, Volume: 200 Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Animals, Newborn; Apnea; Brain Stem; Carotid Body; Central Nervous System Stimulants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Phrenic Nerve; Quinazolines; Rats, Sprague-Dawley; Respiration; Theobromine; Theophylline; Tissue Culture Techniques; Triazoles; Xanthines	2014
Predictive Factors for Efficacy and Safety of Prophylactic Theophylline for Extubation in Infants with Apnea of Prematurity. PloS one, 2016, Volume: 11, Issue:7 Topics: Airway Extubation; Apnea; Bronchodilator Agents; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care, Neonatal; Japan; Male; Multivariate Analysis; Odds Ratio; Respiration, Artificial; Retrospective Studies; ROC Curve; Theophylline	2016
Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants. British journal of clinical pharmacology, 2017, Volume: 83, Issue:6 Topics: Aging; Apnea; Bronchodilator Agents; Cytochrome P-450 CYP1A2; Female; Genotype; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Theophylline; Uric Acid; Xanthines	2017
Factors affecting the efficacy and safety of aminophylline in treatment of apnea of prematurity in neonatal intensive care unit. Pediatrics and neonatology, 2019, Volume: 60, Issue:1 Topics: Aminophylline; Apnea; Birth Weight; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Intensive Care Units, Neonatal; Male; Odds Ratio; Retrospective Studies; ROC Curve; Theophylline	2019
Severe pallid breath-holding spells treated with low-dose theophylline. Brain & development, 2021, Volume: 43, Issue:2 Topics: Apnea; Breath Holding; Dose-Response Relationship, Drug; Heart Arrest; Humans; Infant; Male; Seizures; Syncope; Theophylline	2021
Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC-ESI-MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water as a surrogate matrix. Biomedical chromatography : BMC, 2022, Volume: 36, Issue:11 Topics: Animals; Apnea; Caffeine; Drug Monitoring; Humans; Infant, Newborn; Infant, Premature; Rats; Tandem Mass Spectrometry; Theobromine; Theophylline; Water	2022