theophylline has been researched along with amrinone in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (35.90) | 18.7374 |
| 1990's | 10 (25.64) | 18.2507 |
| 2000's | 6 (15.38) | 29.6817 |
| 2010's | 9 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bristol, JA; Cain, MH; Weishaar, RE | 1 |
| Kasugai, S; Miyamoto, K; Ohya, K; Sawanishi, H; Suzuki, H; Suzuki, N; Takagi, K; Waki, Y; Yamamoto, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Meyer, W; Scholz, H | 1 |
| Kishi, Y; Numano, F | 1 |
| Greeff, K; Schmitt, M | 1 |
| Rodger, IW; Shahid, M | 1 |
| Dorigo, P; Gaion, RM; Maragno, I; Marcomini, A; Mazzetto, S | 1 |
| Boyd, DK; Evans, DB; Quade, M; Schenden, JA; Weishaar, RE | 1 |
| Ceroni, G; Dorigo, P; Gaion, RM; Giacometti, A; Maragno, I; Valentini, E | 1 |
| Ceroni, G; Dorigo, P; Gaion, RM; Giacometti, A; Maragno, I | 1 |
| Dorigo, P; Maragno, I | 1 |
| Brown, L; Erdmann, E | 1 |
| Chesebro, JH; Morgan, JP; Pluth, JR; Puga, FJ; Schaff, HV | 1 |
| Le Jemtel, TH; Maskin, CS; Sonnenblick, EH | 1 |
| Hosokawa, T; Kojima, M; Mori, T; Yabuuchi, Y; Yamashita, S | 1 |
| Arner, P; Bolinder, J; Hagström-Toft, E; Hellmér, J | 1 |
| Fujimura, A; Harada, K; Kumagai, Y; Ohashi, K | 1 |
| Pfaffendorf, M; van Wezel, HB; van Zwieten, PA; Vroom, MB | 1 |
| Hassan, S; Mori, M; Obara, H | 1 |
| Haskó, G; Németh, ZH; Szabó, C; Vizi, ES | 1 |
| Braune, J; Ebert, U; Grossmann, M; Kirch, W | 1 |
| Arner, P; Degerman, E; Enoksson, S; Hagström-Toft, E; Large, V | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M | 1 |
| Sadan, G; Usta, C | 1 |
3 review(s) available for theophylline and amrinone
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity | 1985 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
2 trial(s) available for theophylline and amrinone
| Article | Year |
|---|---|
Comparison of venodilatory effect of amrinone and theophylline in human subjects.
Topics: Adrenergic alpha-Agonists; Adult; Amrinone; Cross-Over Studies; Dose-Response Relationship, Drug; Hand; Humans; Male; Phenylephrine; Phosphodiesterase Inhibitors; Theophylline; Vasodilation; Vasodilator Agents; Veins | 1995 |
Dilatory effects of phosphodiesterase inhibitors on human hand veins in vivo.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Amrinone; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enoximone; Female; Hand; Humans; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Theophylline; Vasodilation; Vasodilator Agents; Veins | 1998 |
34 other study(ies) available for theophylline and amrinone
| Article | Year |
|---|---|
Selective inhibitors of cyclic AMP-specific phosphodiesterase: heterocycle-condensed purines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Depression, Chemical; Heart; Isoenzymes; Male; Models, Chemical; Muscle Relaxation; Myocardium; Phosphodiesterase Inhibitors; Purines; Shrews; Trachea | 1997 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Phosphodiesterase-inhibiting properties of newer inotropic agents.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Theophylline | 1986 |
Involvement of cyclic AMP in vasodilatation by amrinone: a comparative study with 3-isobutyl-methyl-xanthine (IBMX).
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Amrinone; Animals; Aorta; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Potassium; Rabbits; Sulfonamides; Theophylline; Vasodilation | 1986 |
Interaction of phosphodiesterase inhibitors triamterene, papaverine, theophylline, IBMX and amrinone with other positive inotropic acting substances on isolated guinea-pig atria.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Colforsin; Drug Interactions; Electric Stimulation; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Male; Metaproterenol; Myocardial Contraction; Papaverine; Phosphodiesterase Inhibitors; Stimulation, Chemical; Theophylline; Triamterene | 1987 |
Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Carbamates; Cardiovascular Agents; Cyclic AMP; Cyclic GMP; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Rabbits; Theophylline | 1989 |
Amrinone potentiates catecholamine-induced lipolysis in fat cells.
Topics: Adenosine; Adipose Tissue; Amrinone; Animals; Calcium; Lipolysis; Male; Norepinephrine; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Studies aimed at elucidating the mechanism of action of CI-914, a new cardiotonic agent.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aminopyridines; Amrinone; Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dogs; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Mitochondria, Heart; Myocardial Contraction; Myocardium; Ouabain; Papaverine; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Rabbits; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Theophylline | 1985 |
The response of isolated guinea-pig aorta to amrinone.
Topics: Adenosine; Adenosine Deaminase; Amrinone; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Quinidine; Theophylline | 1988 |
Possible role of adenosine in the relaxant effect of amrinone on guinea-pig ileum.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Amrinone; Animals; Dipyridamole; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Relaxants, Central; Muscle, Smooth; Rats; Theophylline | 1987 |
Interaction of amrinone with endogenous adenosine in guinea-pig atria.
Topics: Adenosine; Adenosine Deaminase; Aminopyridines; Amrinone; Animals; Cardiac Glycosides; Cardiotonic Agents; Dipyridamole; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Reserpine; Theophylline | 1986 |
Concentration-response curves of positive inotropic agents before and after ouabain pretreatment.
Topics: Aminopyridines; Amrinone; Animals; Cardiotonic Agents; Cats; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Metaproterenol; Myocardial Contraction; Ouabain; Papillary Muscles; Phenylephrine; Stimulation, Chemical; Theophylline | 1985 |
Intracellular calcium transients in human working myocardium as detected with aequorin.
Topics: Aequorin; Aminopyridines; Amrinone; Calcium; Culture Techniques; Digitalis Glycosides; Humans; Ion Channels; Isoproterenol; Luminescent Proteins; Myocardial Contraction; Myocardium; Papillary Muscles; Theophylline; Time Factors | 1984 |
Inotropic drugs for treatment of the failing heart.
Topics: Aminophylline; Aminopyridines; Amrinone; Cardiotonic Agents; Catecholamines; Digitalis Glycosides; Glucagon; Heart Failure; Hemodynamics; Humans; Milrinone; Myocardial Contraction; Pyridones; Receptors, Adrenergic, beta; Theophylline | 1984 |
In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Cats; Dobutamine; Dogs; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phentolamine; Pindolol; Pyrazines; Quinolines; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase; Theophylline | 1984 |
Effect of phosphodiesterase inhibition with amrinone or theophylline on lipolysis and blood flow in human adipose tissue in vivo as measured with microdialysis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Adolescent; Adult; Amrinone; Blood Flow Velocity; Dialysis; Ethanol; Female; Glycerol; Humans; Isoenzymes; Kinetics; Lipolysis; Male; Middle Aged; Theophylline | 1993 |
Effect of phosphodiesterase inhibitors on human arteries in vitro.
Topics: Adolescent; Adult; Amrinone; Analgesics; Anilides; Arginine; Arteries; Dipyridamole; Enoximone; Female; Glyburide; Humans; In Vitro Techniques; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Pyridones; Theophylline; Vasoconstriction; Vasodilation | 1996 |
The vasorelaxant effects of amrinone on neonatal rabbit thoracic aortic strips.
Topics: Adrenergic beta-Antagonists; Amrinone; Animals; Animals, Newborn; Aorta, Thoracic; Colforsin; Culture Techniques; Female; Isoproterenol; Male; Phosphodiesterase Inhibitors; Rabbits; Theophylline; Vasodilator Agents | 1996 |
Amrinone and theophylline differentially regulate cytokine and nitric oxide production in endotoxemic mice.
Topics: Amrinone; Animals; Cyclic AMP; Cyclic GMP; Cytokines; Endotoxemia; Interleukin-10; Interleukin-6; Lipopolysaccharides; Male; Mice; Nitric Oxide; Phosphodiesterase Inhibitors; Theophylline; Tumor Necrosis Factor-alpha | 1997 |
Various phosphodiesterase subtypes mediate the in vivo antilipolytic effect of insulin on adipose tissue and skeletal muscle in man.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Amrinone; Blood Glucose; Dialysis Solutions; Dipyridamole; Ethanol; Female; Glycerol; Humans; Hypoglycemic Agents; Insulin; Isoenzymes; Lipolysis; Male; Middle Aged; Muscle, Skeletal; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Regional Blood Flow; Rolipram; Sterol Esterase; Theophylline; Vasodilator Agents | 1998 |
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines | 1999 |
Comparison of the effects of selective III, IV and nonselective phosphodiesterase inhibitors on isolated tracheal preparations in streptozotocin-diabetic rats.
Topics: Amrinone; Animals; Carbachol; Cardiotonic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle Relaxation; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Rolipram; Streptozocin; Theophylline; Trachea | 2000 |