theophylline and allopurinol

theophylline has been researched along with allopurinol in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (35.00)	18.7374
1990's	12 (20.00)	18.2507
2000's	15 (25.00)	29.6817
2010's	11 (18.33)	24.3611
2020's	1 (1.67)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Berizzi, A; Bird, L; Culurgioni, S; Navratilova, IH; Olsen, RHJ; Rawlins, PB; Robinson, S; Shepherd, C; Thompson, LEJ; Varzandeh, S	1
Fain, JN	1
Birkett, DJ; Farkas, J; Grygiel, JJ; Wing, LM	1
Grift, J; Ketting, D; van Bree-Blom, EJ; van Gennip, AH; Wadman, SK	1
Johnson, GF; Kiser, EJ; Witte, DL	1
Canada, AT; Seidman, J; Woodman, TF	1
Badawy, AA; Evans, M	1
Lohmann, SM; Miech, RP	1
Hossie, RD; McGilveray, IJ; Sved, S	1
Bircher, J; Brandes, A; Compagnone, D; Hille, H; Münch, B; Ullrich, D	1
Gottehrer, A; Vaughan, LM	1
Gotoh, K; Hori, M; Inoue, M; Iwai, K; Iwakura, K; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Sato, H	1
Birkett, DJ; Day, RO; Miners, JO	1
Griot, C; Peterhans, E; Richard, A; Stocker, R; Vandevelde, M	1
Loi, CM; Vestal, RE; Wei, XX	1
Raasch, RH	1
Birkett, DJ; Kjellen, G; Lelo, A; Miners, JO	1
Ben-Zvi, Z; Gorodischer, R; Margalith, M; Warszawski, D; Yaari, A	1
Günther, K; Modersohn, D; Pankau, H; Scheider, D; Tronicke, E; Uhlich, C; Urbaszek, W	1
Kolassa, N; Pfleger, K; Volkmer, I	1
Chytil, F	1
Bukowskyj, M; Munt, PW; Nakatsu, K	1
Davies, JI; Grahn, MF	1
Koroleva, TR; Korostovtsev, DS; Kozhemiakin, LA	1
Kela, U; Trivedi, CP; Vijayvargiya, R	1
Garcia, I; Segura, J; Tarrus, E	1
Cupit, GC; Powell, JR; Riegelman, S; Sheiner, LB; Vozeh, S	1
Manfredi, RL; Vesell, ES	1
Kraupp, M; Marz, R; Razavi, M	1
Furukawa, H; Kawashima, Y; Lee, RG; Takeyoshi, I; Todo, S	1
Goriki, K; Ochiai, M; Okusaki, K; Takahashi, H; Toda, K; Tokunou, H; Uehara, S	1
Du Souich, P; El-Kadi, A; Haddad, P; Serrar, H	1
Madhavi, YS; Madyastha, KM; Sridhar, GR; Vadiraja, BB	1
Miertus, S; Pizzariello, A; Stredansky, M; Svorc, J	1
Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM	1
Kostromina, KN; Parkhomenko, IM; Pavlov, AS; Simakina, EP	1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT	1
Boqué Argemi, R; Borràs Joaquina, A; Coll Artés, R; Vaqué Cabañas, A	1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A	1
Brincat, S; Hilton, R	1
Gunawardhana, L; Naik, H; Tsai, M; Wu, JT	1

Reviews

4 review(s) available for theophylline and allopurinol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effect of xanthine-related compounds on a theophylline assay using theophylline oxidase. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:12 Topics: Allopurinol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Oxidoreductases; Oxypurinol; Pentoxifylline; Theophylline; Xanthines	1992
Theophylline reassessed. Annals of internal medicine, 1984, Volume: 101, Issue:1 Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; Caffeine; Contraceptives, Oral; Cooking; Cystic Fibrosis; Drug Interactions; Erythromycin; Female; Heart Diseases; Histamine H2 Antagonists; Humans; Hypoxia; Infections; Kinetics; Liver Diseases; Lung Diseases, Obstructive; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Respiration Disorders; Sleep; Smoking; Theophylline	1984
Prevention of acute kidney injury. British journal of hospital medicine (London, England : 2005), 2008, Volume: 69, Issue:8 Topics: Acetylcysteine; Acute Kidney Injury; Allopurinol; Aminoglycosides; Amphotericin B; Antifungal Agents; Contrast Media; Dehydration; Dopamine Agonists; Glomerular Filtration Rate; Humans; Hypovolemia; Natriuretic Peptides; Renal Agents; Renal Circulation; Sodium Potassium Chloride Symporter Inhibitors; Theophylline	2008

Trials

2 trial(s) available for theophylline and allopurinol

Article	Year
Inhibition of theophylline metabolism by mexiletine in young male and female nonsmokers. Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:5 Topics: Adult; Allopurinol; Analysis of Variance; Drug Evaluation; Female; Half-Life; Humans; In Vitro Techniques; Male; Mexiletine; Smoking; Theophylline; Xanthine Oxidase	1991
The effects of xanthine oxidase inhibition by febuxostat on the pharmacokinetics of theophylline. International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:5 Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Male; Middle Aged; Theophylline; Thiazoles; Xanthine Oxidase	2012

Article

Year

Inhibition of theophylline metabolism by mexiletine in young male and female nonsmokers.

Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:5

Topics: Adult; Allopurinol; Analysis of Variance; Drug Evaluation; Female; Half-Life; Humans; In Vitro Techniques; Male; Mexiletine; Smoking; Theophylline; Xanthine Oxidase

1991

The effects of xanthine oxidase inhibition by febuxostat on the pharmacokinetics of theophylline.

International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:5

Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Male; Middle Aged; Theophylline; Thiazoles; Xanthine Oxidase

2012

Other Studies

54 other study(ies) available for theophylline and allopurinol

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments. ACS medicinal chemistry letters, 2022, Jul-14, Volume: 13, Issue:7 Topics:	2022
Effect of lipolytic agents on adenosine and AMP formation by fat cells. Biochimica et biophysica acta, 1979, Jun-21, Volume: 573, Issue:3 Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adipose Tissue; Allopurinol; Animals; Cyclic AMP; Female; In Vitro Techniques; Norepinephrine; Oleic Acids; Rats; Theophylline; Xanthine Dehydrogenase	1979
Effects of allopurinol on theophylline metabolism and clearance. Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:5 Topics: Adult; Allopurinol; Drug Administration Schedule; Humans; Kinetics; Male; Smoking; Theophylline; Xanthines	1979
Urinary excretion of methylated purines in man and in the rat after the administration of theophylline. Journal of chromatography, 1979, Aug-21, Volume: 163, Issue:4 Topics: Allopurinol; Animals; Asthma; Child; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Male; Purines; Rats; Theophylline; Xanthine Oxidase	1979
Serum uric acid determined by reversed-phase liquid chromatography with spectrophotometric detection. Clinical chemistry, 1978, Volume: 24, Issue:4 Topics: Acetaminophen; Allopurinol; Chromatography, Liquid; Drug Interactions; Humans; Methods; Oxypurinol; Salicylates; Spectrophotometry, Ultraviolet; Theophylline; Urate Oxidase; Uric Acid	1978
Interference of allopurinol and alloxanthine in ultraviolet theophylline assay. American journal of hospital pharmacy, 1977, Volume: 34, Issue:9 Topics: Allopurinol; Drug Interactions; Humans; Methods; Oxypurinol; Pyrimidines; Spectrophotometry, Ultraviolet; Theophylline	1977
The role of free serum tryptophan in the biphasic effect of acute ethanol administration on the concentrations of rat brain tryptophan, 5-hydroxytryptamine and 5-hydroxyindol-3-ylacetic acid. The Biochemical journal, 1976, Nov-15, Volume: 160, Issue:2 Topics: Allopurinol; Animals; Brain; Brain Chemistry; Ergotamine; Ethanol; Fatty Acids, Nonesterified; Hydroxyindoleacetic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Rats; Serotonin; Sucrose; Theophylline; Tryptophan; Tryptophan Oxygenase	1976
Theophylline metabolism by the rat liver microsomal system. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 196, Issue:1 Topics: Aldehyde Oxidoreductases; Animals; Cytosol; Female; Half-Life; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Proadifen; Rats; Theophylline; Time Factors; Xanthine Oxidase	1976
The human metabolism of caffeine to theophylline. Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:2 Topics: Allopurinol; Aminophylline; Biological Availability; Caffeine; Humans; Male; Theophylline; Time Factors	1976
Urinary caffeine metabolites in man. Age-dependent changes and pattern in various clinical situations. European journal of clinical pharmacology, 1992, Volume: 43, Issue:2 Topics: Adolescent; Adult; Age Factors; Allopurinol; Caffeine; Child; Cimetidine; Drug Interactions; Female; Humans; Kidney Failure, Chronic; Liver Cirrhosis; Male; Phenytoin; Smoking; Theophylline	1992
Role of oxygen-derived free radicals in myocardial edema and ischemia in coronary microvascular embolization. Circulation, 1991, Volume: 84, Issue:2 Topics: Allopurinol; Animals; Ascorbic Acid; Body Water; Cardiomyopathies; Coronary Disease; Dogs; Edema; Embolism; Free Radical Scavengers; Free Radicals; Microcirculation; Microspheres; Oxygen; Superoxide Dismutase; Theophylline	1991
1-Methylxanthine derived from theophylline as an in vivo biochemical probe of allopurinol effect. British journal of clinical pharmacology, 1991, Volume: 32, Issue:2 Topics: Adult; Allopurinol; Biomarkers; Female; Humans; Male; Oxypurinol; Theophylline; Uric Acid; Xanthines	1991
Selective degeneration of oligodendrocytes mediated by reactive oxygen species. Free radical research communications, 1990, Volume: 11, Issue:4-5 Topics: Animals; Benzamides; Brain; Cell Survival; Cells, Cultured; Demyelinating Diseases; Dogs; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Oligodendroglia; Oxygen; Superoxides; Theophylline; Xanthine; Xanthine Oxidase; Xanthines	1990
Interactions of oral antibiotics and common chronic medications. Geriatrics, 1987, Volume: 42, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Allopurinol; Ampicillin; Antacids; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Digoxin; Drug Combinations; Drug Interactions; Erythromycin; Humans; Sulfamethoxazole; Sulfonamides; Sulfonylurea Compounds; Tetracycline; Theophylline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Warfarin	1987
Paraxanthine metabolism in humans: determination of metabolic partial clearances and effects of allopurinol and cimetidine. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1 Topics: Acetylation; Adult; Allopurinol; Caffeine; Cimetidine; Cytochrome P-450 Enzyme System; Humans; Kidney; Male; Metabolic Clearance Rate; Theophylline	1989
Changes in theophylline metabolism during postnatal development in rat liver slices. Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18 Topics: Allopurinol; Animals; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Liver; Proadifen; Rats; Theobromine; Theophylline	1986
[Influence of metabolism-inhibiting as well as metabolism-accelerating and ionotropic drugs on myocardial survival time in the rat under anoxia conditions]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Aug-15, Volume: 29, Issue:16 Topics: Adrenergic beta-Antagonists; Allopurinol; Animals; Carnitine; Cell Survival; Digitoxin; Female; Heart; Hypoxia; Male; Metaproterenol; Myocardium; Norepinephrine; Practolol; Prednisolone; Propranolol; Rats; Strophanthins; Theophylline; Thiamine Pyrophosphate	1974
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:12 Topics: Alkaloids; Allopurinol; Animals; Carbon Isotopes; Cocaine; Depression, Chemical; Dipyridamole; Drug Synergism; Ethylenediamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardium; Nitroglycerin; Nucleosides; Ouabain; Papaverine; Prenylamine; Probenecid; Pyridines; Reserpine; Stimulation, Chemical; Theophylline; Triamterene; Vasodilator Agents; Verapamil	1969
Activation of liver tryptophan oxygenase by adenosine 3',5'-phosphate and by other purine derivatives. The Journal of biological chemistry, 1968, Mar-10, Volume: 243, Issue:5 Topics: Adenine Nucleotides; Adenosine Triphosphate; Allopurinol; Animals; Catalase; Hemoglobins; Hydrogen Peroxide; Hypoxanthines; Liver; Male; Nitrogen; Oxygen; Rats; Theophylline; Tryptophan Oxygenase; Uric Acid; Xanthine Oxidase	1968
Xanthine oxidase in adipose tissue: potential effects on lipolytic activity [proceedings]. Biochemical Society transactions, 1980, Volume: 8, Issue:3 Topics: Adenosine Deaminase; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Lipid Mobilization; Male; Norepinephrine; Rats; Theophylline; Xanthine Oxidase; Xanthines	1980
[Xanthine oxidase--xanthines as a system of endogenous regulation of phosphodiesterase activity]. Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 90, Issue:12 Topics: Allopurinol; Animals; Cyclic AMP; In Vitro Techniques; Liver; Molybdenum; Phosphoric Diester Hydrolases; Quaternary Ammonium Compounds; Rats; Theophylline; Xanthine Oxidase; Xanthines	1980
Inhibitory effects of methylxanthines on the activity of xanthine oxidase. Life sciences, 1980, Dec-01, Volume: 27, Issue:22 Topics: Animals; Brain; Buffaloes; Caffeine; Female; In Vitro Techniques; Kidney; Kinetics; Lung; Milk; Myocardium; Rats; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase; Xanthines	1980
Human metabolism of 7-substituted theophyllines: N3-demethylation and lack of oxidation of proxyphylline. Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:5 Topics: Aminophylline; Animals; Biotransformation; Dealkylation; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Oxidation-Reduction; Theophylline; Xanthine Oxidase	1981
Influence of allopurinol on theophylline disposition in adults. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:2 Topics: Adult; Allopurinol; Humans; Kinetics; Male; Smoking; Theophylline; Time Factors	1980
Inhibition of theophylline metabolism by long-term allopurinol administration. Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:2 Topics: Adult; Allopurinol; Dose-Response Relationship, Drug; Humans; Intestinal Absorption; Male; Metabolic Clearance Rate; Theophylline	1981
Allopurinol transport in human erythrocytes. Biochemical pharmacology, 1993, Feb-24, Volume: 45, Issue:4 Topics: Allopurinol; Biological Transport; Erythrocytes; Humans; Kinetics; Oxypurinol; Theophylline	1993
Ischemia and reperfusion injury of the human colon and ileum. Transplantation proceedings, 1996, Volume: 28, Issue:5 Topics: Adenosine; Allopurinol; Biomarkers; Colon; Glutathione; Humans; Ileum; Insulin; Intestinal Mucosa; Membrane Potentials; Muscle, Smooth; Organ Preservation; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Theophylline; Transplantation, Homologous	1996
Gout due to xanthine derivatives. British journal of rheumatology, 1997, Volume: 36, Issue:10 Topics: Allopurinol; Aminophylline; Asthma; Benzbromarone; Bronchodilator Agents; Drug Therapy, Combination; Female; Gout; Humans; Middle Aged; Probenecid; Theophylline; Uric Acid; Uricosuric Agents	1997
Cytochrome P-450 content and activity after cold storage of rat hepatocytes in university of wisconsin and sodium-lactobionate-sucrose solutions. Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1999, Volume: 5, Issue:2 Topics: Adenosine; Allopurinol; Animals; Cell Survival; Chlorpromazine; Cryopreservation; Cytochrome P-450 Enzyme System; Disaccharides; Glutathione; Insulin; Liver; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Sucrose; Theophylline	1999
Purification and partial characterization of caffeine oxidase--A novel enzyme from a mixed culture consortium. Biochemical and biophysical research communications, 1999, Sep-24, Volume: 263, Issue:2 Topics: Caffeine; Klebsiella; Oxidation-Reduction; Oxygenases; Rhodococcus; Substrate Specificity; Theobromine; Theophylline; Uric Acid; Xanthine Oxidase	1999
Selective and sensitive biosensor for theophylline based on xanthine oxidase electrode. Analytical biochemistry, 2000, Oct-15, Volume: 285, Issue:2 Topics: Biosensing Techniques; Electric Conductivity; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Monitoring, Physiologic; Sensitivity and Specificity; Substrate Specificity; Theophylline; Time Factors; Trehalose; Xanthine Oxidase; Xanthines	2000
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:2 Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase	2001
[Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 2001, Issue:8 Topics: Allopurinol; Antimetabolites; Antimetabolites, Antineoplastic; Cell Survival; Cobalt Radioisotopes; Fluorouracil; Gamma Rays; HeLa Cells; Humans; Lethal Dose 50; Mercaptopurine; Phosphodiesterase Inhibitors; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage; Tegafur; Theophylline	2001
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11 Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines	1997
[Theophylline induced gynecomastia]. Medicina clinica, 2005, May-14, Volume: 124, Issue:18 Topics: Aged; Allopurinol; Drug Interactions; Enzyme Inhibitors; Gynecomastia; Humans; Male; Theophylline; Vasodilator Agents	2005
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios. Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines	2007