theophylline has been researched along with adenosine in 1663 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 708 (42.57) | 18.7374 |
| 1990's | 657 (39.51) | 18.2507 |
| 2000's | 223 (13.41) | 29.6817 |
| 2010's | 65 (3.91) | 24.3611 |
| 2020's | 10 (0.60) | 2.80 |
| Authors | Studies |
|---|---|
| Bey, P; Demeter, DA; Dudley, MW; Lentz, NL; Meng, EC; Ogden, AM; Peet, NP; Weintraub, HJ | 1 |
| Daly, JW | 1 |
| Borea, PA; Dalpiaz, A; Gilli, G; Gilli, P; Scatturin, A; Varani, K | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Berizzi, A; Bird, L; Culurgioni, S; Navratilova, IH; Olsen, RHJ; Rawlins, PB; Robinson, S; Shepherd, C; Thompson, LEJ; Varzandeh, S | 1 |
| Kostopoulos, GK; Phillis, JW | 1 |
| Fedorko, ME; Levine, RF | 1 |
| Fredholm, BB; Hjemdahl, P | 2 |
| Farmer, JB; Farrar, DG | 1 |
| Dabney, JM; Haddy, FJ; Merrill, GF | 1 |
| Costa, E; Schwartz, JP | 1 |
| Ng, SK; Rogers, J; Sanwal, BD | 1 |
| Findlay, SR; Lichtenstein, LM; Marone, G | 1 |
| Edstrom, JP; Kirkpatrick, JR; Kostopoulos, GK; Phillis, JW | 1 |
| Daly, JW; Smellie, FW; Wells, JN | 1 |
| Laurent, P; Ristori, MT | 1 |
| Fain, JN; Wieser, PB | 1 |
| Clark, RB; Cubeddu, L; Johnson, GL; Ortmann, R; Perkins, JP; Su, YF | 1 |
| Ebert, R; Erbler, HC; Schwabe, U | 1 |
| Kalisker, A; Moore, MM; Perkins, JP; Su, YF | 1 |
| Bach, JF; Bach, MA; Fournier, C | 1 |
| Weiner, M | 1 |
| Makman, MH; Wilkening, D | 1 |
| Isaksson, O; Rosberg, S; Selstam, G | 1 |
| Mahlmann, LJ; Schooley, JC | 1 |
| Gullis, RJ; Rowe, CE | 1 |
| Carson, DA; Seegmiller, JE | 1 |
| Chen, CC; Lifrak, E; Wishnow, RM | 1 |
| Huot, J; Jard, S; Penit, J | 1 |
| Singhal, RL; Sutherland, DJ | 1 |
| Kapoor, HC; Sachar, RC | 1 |
| Carpenter, JG; Peck, WA; Schuster, RJ | 1 |
| Yasunaga, K | 1 |
| Ally, AI; Nakatsu, K | 1 |
| Deshpande, AK; Siddiqui, MA | 1 |
| Adachi, K; Halprin, KM; Iizuka, H; Levine, V | 1 |
| Roch, P; Salamin, A | 1 |
| Dretchen, KL; Morgenroth, VH; Skirboll, LR; Standaert, FG | 1 |
| Daly, JW; Dismukes, RK; Stalvey, L | 1 |
| Gerrard, JM; Stoddard, S; Townsend, D; White, JG; Witkop, CJ | 1 |
| Bär, HP; Frew, R; McKenzie, SG | 1 |
| Shimizu, H; Yamamura, Y | 1 |
| Bockaert, J; Perez, M; Premont, J | 2 |
| Ozato, K | 1 |
| Borysenko, JZ; Karnovsky, MJ; Ukena, TE | 1 |
| Asano, T; Hidaka, H; Ochiai, Y | 1 |
| Buckley, JT | 1 |
| Saito, M | 1 |
| Daly, JW; Ohga, Y | 1 |
| Heikkinen, ER | 1 |
| Finlayson, LH; Osborne, MP | 1 |
| Clanachan, AS; Johns, A; Paton, DM | 1 |
| Green, RD | 2 |
| Anderson, RG; Johansson, SR | 1 |
| Bartos, F; Chmelar, V; Kanta, J | 1 |
| Fredholm, BB; Hedqvist, P; Olundh, S | 1 |
| Cook, MA; Hamilton, JT; Okwusaba, FK | 1 |
| Sattin, A; Stone, TW; Taylor, DA | 1 |
| Mosimann, WF; Mueller, AL; Weiner, N | 1 |
| Dominguez, ML; Ribeiro, JA | 1 |
| Cooper, DM; Gleed, C | 1 |
| Muller, MJ; Paton, DM | 1 |
| Fain, JN | 2 |
| Hymson, DL; Sakai, KK; Shapiro, R | 1 |
| Newman, M; Traversa, U | 1 |
| Bonnafous, JC; Dornand, J; Mani, JC | 1 |
| Bartlett, V; Nakatsu, K; Stewart, RR | 1 |
| Moylan, RD; Westfall, TC | 1 |
| Lokhandwala, MF | 1 |
| Brodin, K; Fredholm, BB; Strandberg, K | 1 |
| Chang, MM; Ferrendelli, JA; Kinscherf, DA; Morgan, JF | 1 |
| Rall, TW; Sattin, A; Zanella, J | 1 |
| Kalix, P; Roch, P | 1 |
| Cantau, B; Huot, J; Jard, S; Pénit, J | 2 |
| Spinowitz, BS; Zadunaisky, JA | 1 |
| Baba, S; Hasegawa, M; Kobayashi, T; Murakami, K; Seki, M; Taniguchi, H; Watanabe, Y | 1 |
| Haddy, FJ | 1 |
| Andersson, KE; Sjögren, C | 2 |
| Michaelis, EK; Michaelis, ML; Myers, SL | 1 |
| Dominguez, ML; Gonçalves, MJ; Ribeiro, JA | 1 |
| Chen, WT; Dabney, JM; Haddy, FJ; Scott, JB; Swindall, BT | 1 |
| Baer, HP; Frew, R | 1 |
| Edstrom, JP; Ellis, SW; Kirkpatrick, JR; Phillis, JW | 1 |
| Deeprose, RD; Duncan, GS; Harvey, RJ; Wolberg, G; Zimmerman, TP | 1 |
| Nakanishi, H; Ohtaki, Y; Ueda, J | 1 |
| Kemper, R; Osswald, H; Schmitz, HJ | 1 |
| Colin, DA; Leray, C | 1 |
| Bieck, P; Vapaatalo, H; Westermann, E | 1 |
| Cook, MA; Hamilton, JT; Okwuasaba, FK | 1 |
| Katano, Y; Nakagawa, Y; Nakazawa, M; Takeda, K; Tsukada, T | 1 |
| Fredholm, BB | 6 |
| Harms, HH; Mulder, AH; Wardeh, G | 1 |
| Holzmann, S; Kukovetz, WR; Pöch, G; Rinner, I; Wurm, A | 1 |
| Hayashi, E; Kunitomo, M; Mori, M; Shinozuka, K; Yamada, S | 1 |
| Hjemdahl, P; Sollevi, A | 1 |
| Haddy, FJ; Scott, JB; Tabaie, HM | 1 |
| Cook, MA; Hamilton, JT; Okwasaba, FK | 1 |
| Bundman, D; Freund, M; Peterson, RN | 1 |
| Davis, CC; Khouri, EM; Olsson, RA | 1 |
| Clark, RB; Seney, MN | 1 |
| Kuschinsky, W; Wahl, M | 2 |
| Knoll, J; Vizi, ES | 1 |
| Lang, R; Oberdörster, G; Zimmer, R | 2 |
| Sjöberg, B; WAHLSTRöm, BA | 1 |
| Osswald, H | 1 |
| Blume, AJ; Foster, CJ | 1 |
| Hamilton, JT; Okwuasaba, FK | 1 |
| Bünger, R; Gerlach, E; Haddy, FJ | 1 |
| Gross, GJ; Hardman, HF; Warltier, DC | 1 |
| Jhamandas, KH; Sawynok, J | 1 |
| Davis, CJ; Khouri, EM; Olsson, RA; Patterson, RE | 1 |
| Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S | 1 |
| Ali, S; Metzger, WJ; Mustafa, SJ | 3 |
| Power, GG; Yoneyama, Y | 1 |
| Garaschuk, O; Kovalchuk, Yu; Krishtal, O | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitabatake, A; Kitakaze, M; Sato, H; Takashima, S | 2 |
| Brink, A; Fuder, H; Meincke, M; Tauber, U | 1 |
| Byczko, Z; Murphy, MG | 1 |
| Fredholm, BB; Gerwins, P | 1 |
| Furlong, TJ; Pierce, KD; Selbie, LA; Shine, J | 1 |
| Acevedo, CG; Contreras, E; Escalona, J; Huidobro-Toro, JP; Lewin, J | 1 |
| Gadd, GM; Sabie, FT | 1 |
| Földes, FF; Nagano, O; Nakatsuka, H; Ohta, Y; Reich, D; Sperlagh, B; Vizi, ES | 1 |
| DeLander, GE; Mosberg, HI; Porreca, F | 1 |
| Abramson, SB; Cronstein, BN; Hirschhorn, R; Levin, RI; Philips, M; Weissmann, G | 1 |
| Bowmer, CJ; Collis, MG; Munsey, TS; Panjehshahin, MR; Yates, MS | 1 |
| Mersmann, HJ | 3 |
| Connick, JH; Mally, J; Stone, TW | 3 |
| Broadley, KJ; Thorne, JR | 1 |
| Brown, P; Campbell, S; el Nahas, AM; Gandhi, MR; Gray, TA; Morcos, SK; Romanowski, CA | 1 |
| Carlen, PL; Cullen, N | 1 |
| Martin, PL | 2 |
| Matsuda, T; Mori, M; Tsushima, H | 1 |
| Jin, ZL; Lee, TF; Wang, LC | 1 |
| Khoo, HE; Tan, CH; Tey, HB | 2 |
| Ito, S; Mikawa, H; Tsuruta, S | 3 |
| Burnstock, G; Ralevic, V; Rubino, A | 3 |
| De Koninck, Y; Henry, JL | 1 |
| Gordh, T; Karlsten, R; Post, C | 1 |
| Kajikawa, Y; Kusachi, S; Marutani, M; Tsuji, T; Yamasaki, S | 1 |
| Berne, RM; Headrick, JP; Hynes, MR; Matherne, GP; Northington, FJ | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Ishikawa, M; Miura, I; Takeda, T; Takeuchi, K; Yanagi, S | 1 |
| Shibata, S; Tominaga, K; Watanabe, S | 1 |
| Brooks, DP; Wang, YX | 1 |
| Burnstock, G; Kirkpatrick, KA | 1 |
| Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Ragazzi, E | 1 |
| Henry, JL; Li, H | 2 |
| Kaminski, PM; Proctor, KG | 1 |
| Mentzer, RM; Van Wylen, DG; Wang, T | 1 |
| Akai, K; Ashikawa, K; Kanatsuka, H; Komaru, T; Sato, K; Sekiguchi, N; Takishima, T; Wang, Y | 1 |
| Johnston, WE; McGee, S; Toombs, CF; Vinten-Johansen, J | 1 |
| Satoh, K; Taira, N; Yamada, H; Yoneyama, F | 1 |
| Barrett, RJ; Droppleman, DA; Wright, KF | 1 |
| Bauman, LA; Gribkoff, VK | 1 |
| Arizono, K; Brady, FO; Garrett, SH; Xiong, X | 1 |
| Baumgold, J; Jacobson, KA; Nikodijevic, O | 1 |
| Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T | 1 |
| Downey, HF; Lee, SC; Mallet, RT; Shizukuda, Y; Williams, AG | 1 |
| Dux, E; Kreutzberg, GW; Schubert, P | 1 |
| Kurth, CD; Wagerle, LC | 1 |
| Calignano, A; Mancuso, F; Persico, P; Sorrentino, L | 1 |
| Chilton, EL; Lee, SS; Pak, JM | 1 |
| Favilla, S; Salvetti, A; Taddei, S; Virdis, A | 1 |
| Edbladh, M; Edström, A; Ekström, P | 1 |
| Jacobson, KA; Ji, XD; Stiles, GL | 1 |
| Ishizaka, H; Okumura, K; Tsuchiya, T; Yamabe, H; Yasue, H | 1 |
| Gobran, LI; Griese, M; Rooney, SA | 1 |
| Simmons, DA; Winegrad, AI | 1 |
| Smith, DO | 1 |
| Beckman, B; Brookins, J; Fisher, JW; Nakashima, J | 1 |
| Bardenheuer, H; Madel, C; Peter, K; Pöch, G; Thiel, M | 1 |
| Hammarström, M; Samuelson, UE; Wiklund, NP | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| Sawynok, J; Sweeney, MI; White, TD | 2 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 2 |
| Ferré, S; Fuxe, K; Rubio, A | 1 |
| Angielski, S; Kuchta, G; Redlak, M; Szczepańska-Konkel, M | 1 |
| DeLuca, B; Jovetich, M; Middlemiss, PJ; Rathbone, MP | 1 |
| Bjur, RA; Forsyth, KM; Westfall, DP | 1 |
| Collis, MG; Keddie, JR; Shaw, G | 1 |
| Lambert, NA; Teyler, TJ | 1 |
| Ferre, S; Fredholm, BB; Fuxe, K; Johansson, B; von Euler, G | 1 |
| Henry, JA; Minton, NA | 1 |
| Howell, RE; Kinnier, WJ; Muehsam, WT | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Porsius, AJ; Post, MJ; te Biesebeek, JD; van Rooij, HH; Wemer, J | 2 |
| Alexander, B; Mathie, RT | 1 |
| Bailey, SJ; Hourani, SM | 1 |
| Ono, H; Vasko, MR | 1 |
| Lichtenstein, LM; Peachell, PT; Schleimer, RP | 2 |
| Mulè, F; Postorino, A; Serio, R | 1 |
| Canonico, PL; Catania, MV; Nicoletti, F; Rampello, L; Sortino, MA | 1 |
| Ferroni, S; Mager, R; Schubert, P | 1 |
| Baba, T; Fukui, M; Moriguchi, M; Natori, Y; Takeshita, I | 1 |
| Kawamura, M; Kondo, T; Matsui, T; Nakamichi, N; Niitsu, A; Ohno, Y | 1 |
| Aassar, OS; Forrest, JN; Kelley, GG | 1 |
| de la Cruz, JP; Moron, D; Sanchez de la Cuesta, F | 1 |
| Huddart, H; Lynch, M | 1 |
| Hada, J; Hayakawa, T; Hayashi, Y; Morimoto, K; Nii, Y; Shimada, N; Shimizu, H | 1 |
| Espey, MJ; Reid, A; Sawynok, J | 1 |
| Nasir, T; Zarrindast, MR | 1 |
| Bailey, SJ; Hourani, SM; Kitchen, I; Nicholls, J | 1 |
| Cyrys, S; Daut, J; Dischner, A; von Beckerath, N | 1 |
| Ishii, N; Lue, TF; Takahashi, Y; Tanagho, EA | 1 |
| Aas, P; Walday, P | 1 |
| Marshall, JM; Neylon, M | 1 |
| Monteiro, EC; Ribeiro, JA | 1 |
| Belluco, P; Borea, PA; Dorigo, P; Gaion, RM; Maragno, I; Mosti, L | 1 |
| Mitsumoto, Y; Mohri, T; Ohkubo, T | 1 |
| Berman, RF; Jarvis, MF; Lupica, CR | 2 |
| Marshall, JM; Mian, R | 1 |
| Andén, NE; Casas, M; Ferré, S; Grabowska-Andén, M; Herrera-Marschitz, M; Ungerstedt, U | 1 |
| Bennett, MR; Karunanithi, S; Lavidis, NA | 1 |
| Allix, M; Boulu, RG; Callebert, J; Lekieffre, D; Plotkine, M | 1 |
| Christie, JM; Griffiths, TL; Holgate, ST; Parsons, ST | 2 |
| Rothman, SM; Yoon, KW | 1 |
| Lu, Z; Smith, DO | 1 |
| Ameri, A; Jurna, I | 1 |
| Broadley, KJ; Rothaul, AL; Urquhart, RA | 1 |
| Barajas-Lopez, C; North, RA; Surprenant, A | 1 |
| Arzubiaga, C; Biaggioni, I; Paul, S; Puckett, A | 1 |
| Petersen, EN | 1 |
| Savage, AO; Unekwe, PC | 1 |
| Bissonnette, JM; Hohimer, AR; Knopp, SJ | 1 |
| Bealer, SL; Proctor, KG; Stojanov, I | 1 |
| Alexander, B; Burnstock, G; Mathie, RT; Ralevic, V | 1 |
| Dulloo, AG; Girardier, L; Seydoux, J | 1 |
| Holtzman, SG; Mumford, GK | 1 |
| Geiger, JD; Lautt, WW; Legare, DJ; Zhang, Y | 2 |
| Brown, SJ; Evenden, JL; Gill, R; Iversen, SD; Richardson, PJ | 1 |
| Kaley, G; Koller, A; Messina, EJ; Rodenburg, JM; Wolin, MS | 1 |
| Wainwright, LK; Wainwright, SD | 1 |
| Daly, JW; Jacobson, KA; Nikodijević, O; Sarges, R | 1 |
| Contreras, E; Germany, A | 1 |
| Dole, WP; Heller, LJ; Mohrman, DE | 1 |
| Mally, J; Stone, TW | 3 |
| Brezis, M; Dinour, D | 1 |
| Furui, H; Kaneko, M; Satake, T; Suzuki, K; Takagi, K | 1 |
| Advenier, C; Blanc, M; Devillier, P; Gnassounou, JP | 1 |
| Barron, HV; Forrest, JN; Kelley, GG; Poeschla, EM | 1 |
| Advenier, C; Candenas, ML; Cortes, D; D'Ocón, MP; Naline, E | 1 |
| Adamo, EB; Mulè, F; Postorino, A; Serio, R | 1 |
| Pedrinelli, R; Salvetti, A; Taddei, S | 2 |
| Brown, J; Kwok, YN; McIntosh, C | 1 |
| Baldessarini, RJ; Booth, RG | 1 |
| Angello, DA; Berne, RM; Coddington, NM; Headrick, JP | 1 |
| Aranda, JV; Beharry, K; Farri, E; Laudignon, N | 1 |
| Abe, S; Hirano, Y; Hiraoka, M; Sawanobori, T | 1 |
| Brackett, LE; Daly, JW | 1 |
| Driver, AG; Kukoly, CA; Metzger, WJ; Mustafa, SJ | 1 |
| Cadnapaphornchai, P; Golembieski, A; Kellner, D; McDonald, FD | 1 |
| Caswell, AM; Leong, WS; Russell, RG | 1 |
| Kuriyama, H; Li, YJ; Suzuki, H; Zhang, GL | 1 |
| Lin, CI; Wang, GY; Wei, J | 1 |
| Martin, SE; Patterson, RE; Tidmore, WC | 1 |
| Downey, JM; Liu, GS; Olsson, RA; Stanley, AW; Thornton, J; Van Winkle, DM | 1 |
| Brown, GL; Douglas, FL; Kotake, AN; Mustafa, SJ; Sabouni, MH | 1 |
| Kulkarni, SK; Thorat, SN | 1 |
| Gilboe, DP | 1 |
| Haeberli, A; Reinhart, WH; Stark, J; Straub, PW | 1 |
| Joad, JP | 1 |
| Koos, BJ; Matsuda, K | 1 |
| Fastbom, J; Fredholm, BB | 2 |
| Isbrucker, R; Reid, A; Sawynok, J | 1 |
| Bartrup, JT; Connick, JH; Stone, TW | 1 |
| Elphick, M; Godfrey, PP; Powell, T; Taghavi, Z | 1 |
| Barrett, KE; Cohn, JA; Dharmsathaphorn, K; Huott, PA; Wasserman, SI | 1 |
| Heller, LJ; Trachte, GJ | 1 |
| Gilfillan, AM; Welton, AF; Wiggan, GA | 1 |
| Gilbertsen, RB; Lesch, ME; Schrier, DJ; Wright, CD | 1 |
| Cronstein, BN; Salmon, JE | 1 |
| Hattori, Y | 1 |
| Kato, M; Ochi, R; Yamaguchi, H | 1 |
| Howell, RE | 1 |
| Branch, RA; Deray, G; Herzer, WA; Jackson, EK; Sabra, R | 1 |
| Borgdorff, P; Verlato, G | 1 |
| Collis, MG; Nowell, CG; Poucher, SM | 1 |
| Dragunow, M | 1 |
| Lautt, WW; Lockhart, LK | 1 |
| Aranda, JV; Laudignon, N; Varma, DR | 1 |
| Lenders, JW; Smits, P; Thien, T | 1 |
| Cho, CH; Ogle, CW | 1 |
| Baumelou, A; Baumelou, B; Cacoub, P; Deray, G; Jacobs, C; Martinez, F | 1 |
| Merrell, WJ; Rush, W; Seitz, PA; ter Riet, M | 1 |
| Marangos, PJ; von Lubitz, DK | 1 |
| de Mendonça, A; Ribeiro, JA | 2 |
| Ko, KR; Ngai, AC; Winn, HR | 1 |
| Dar, MS | 1 |
| Berman, RF; Lupica, CR; Rosen, JB; Whitcomb, K | 1 |
| d'Almeida, MS; Lautt, WW; Zhang, Y | 1 |
| Britton, SL; Koch, LG; Metting, PJ | 1 |
| Brezis, M; Epstein, FH; Galicka-Piskorska, G; Rosen, S; Silva, P; Spokes, K | 1 |
| Fukumoto, T; Kuroiwa, A; Ochi, T; Tanaka, T | 1 |
| Dunwiddie, TV; Lupica, CR | 1 |
| Daly, JW; Jacobson, KA; Nikodijević, O | 1 |
| Hisa, H; Satoh, S; Yoneda, H | 1 |
| Lee, TF; Wang, LC | 1 |
| Phillis, JW | 1 |
| Fowler, JC | 4 |
| Pinard, E; Puiroud, S; Riche, D; Seylaz, J | 1 |
| Arai, A; Larson, J; Lynch, G | 1 |
| Barraco, RA; Stefano, GB | 1 |
| Barry, SR | 2 |
| Aranda, JV; Beharry, K; Farri, E; Laudignon, N; Rex, J | 1 |
| Baba, K; Hayashi, M; Maeda, T | 1 |
| Proctor, KG; Stojanov, I | 1 |
| Bidani, A; Churchill, P; Ellis, V; Gunther, S; Kontry, T; Rossi, N | 1 |
| Dux, E; Fastbom, J; Fredholm, BB; Rudolphi, K; Ungerstedt, U | 1 |
| Gustafsson, LE; Hedqvist, P; Lindbom, L; Ohlén, A; Persson, MG | 1 |
| Firth, JL; Kendall, DA | 1 |
| Berne, RM; Ely, SW; Esther, JW; Gidday, JM; Rubio, R | 1 |
| Carapella, N; Filippelli, A; Loffreda, A; Marmo, E; Matera, MG; Montanaro, C; Santagata, A; Servodio, R; Susanna, V | 1 |
| Bonifacj, JF; Hasni, H; Laborit, H | 1 |
| Hope, W; Rose'Meyer, RB | 1 |
| Bissonnette, JM; Chao, CR; Hohimer, AR; Knopp, SJ; Notoroberto, NF | 1 |
| de Jong, JW; Van der Meer, P | 1 |
| Franklin, PH; Murray, TF; Zhang, G | 2 |
| Churchill, PC; Wu, PH | 1 |
| Kitos, TE; Michaelis, ML; Mooney, T | 1 |
| Gerber, JG; Nies, AS; Payne, NA | 1 |
| Finney, MJ; Karlsson, JA; Persson, CG | 1 |
| Church, MK; Hughes, PJ | 1 |
| Anand-Srivastava, MB; Cantin, M; Gutkowska, J | 1 |
| Coffin, VL; Spealman, RD | 1 |
| Cederqvist, B; Gustafsson, LE; Wiklund, NP | 2 |
| Church, MK; Hughes, PJ; Vardey, CJ | 1 |
| Butcher, RW; Clark, RB; Proll, MA | 1 |
| Leoutsakos, A; Pearce, FL | 1 |
| Hoskins, DD; Vijayaraghavan, S | 1 |
| Birch, RE; Polmar, SH | 3 |
| Clancy, G; Pratt, AD; Welsh, MJ | 1 |
| Dolphin, AC; Forda, SR; Scott, RH | 1 |
| DeLander, GE; Hopkins, CJ | 2 |
| Fox, IH; John, D | 1 |
| Crowley, JJ; Cusack, BJ; Nielson, CP; Vestal, RE | 1 |
| Dar, MS; Wooles, WR | 1 |
| Brown, SJ; Richardson, PJ | 1 |
| Holtzman, SG | 1 |
| Dodd, PR; Johnston, GA; Watson, WE | 1 |
| Schmeichel, CJ; Thomas, LL | 1 |
| Leung, E; Woodcock, EA | 1 |
| Doi, T; Kuzuna, S; Maki, Y | 1 |
| Napier, FE; Temple, DM | 2 |
| Gensheimer, HP; Lohse, MJ; Maurer, K; Schwabe, U | 1 |
| Belloni, FL; Gerritsen, ME; Liang, BC | 1 |
| Benyon, RC; Church, MK; Hughes, PJ | 1 |
| Beek, D; Kenakin, TP | 1 |
| Silinsky, EM; Vogel, SM | 1 |
| Böhm, M; Brückner, R; Neumann, J; Nose, M; Schmitz, W; Scholz, H | 1 |
| Ribeiro, JA; Sebastião, AM | 3 |
| Haddy, FJ; O'Neill, JT; Steffen, RP | 1 |
| Bazanova, EA; Bukhova, VP; Gnezditskaia, EV; Malkina, LA | 1 |
| Jackman, SA; Nicholson, CD; Wilke, R | 1 |
| Alberts, P | 1 |
| Beermann, B; Brandt, R; Jonzon, B; Sylvén, C | 2 |
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| de Groat, WD; Theobald, RJ | 1 |
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| Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
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| Andreasen, M; Hablitz, JJ; Nedergaard, S; Skov, J | 1 |
| Masereeuw, R; Rongen, GA; van der Hoorn, JW; van der Vliet, JA; Wagener, FA; Warlé, MC; Wever, KE | 1 |
| Abel, T; Florian, C; Halassa, MM; Haydon, PG; Vecsey, CG | 1 |
| Bodnár, Z; Boissonneault, GA; Hajdu, Z; Sipka, S; Szentkereszty, Z | 1 |
| Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y | 1 |
| Hayashi, S; Kabutomori, O; Kashiwagi, H; Kurata, Y; Nishiyama, M; Suehisa, E; Tomiyama, Y; Yamanishi, H | 1 |
| Berdeaux, A; Chenoune, M; Cohen, MV; Darbera, L; Downey, JM; Ghaleh, B; Lidouren, F; Tissier, R | 1 |
| Ankarali, S; Ayyildiz, M; Marangoz, AH; Marangoz, C; Yildirim, M | 1 |
| Drew, KL; Jinka, TR; Tøien, Ø | 1 |
| Rosania, K | 1 |
| Alidzanovic, L; Brostjan, C; Brugger, P; Gnant, M; Kuehrer, I; Schauer, D; Schoppmann, SF; Sommerfeldt, S; Starlinger, P | 1 |
| Braun, JP; Geffré, A; Granat, F; Trumel, C | 1 |
| Duan, SM; Hu, ZA; Wang, HK; Xia, JX; Xiong, JX; Ye, JN | 1 |
| Boushel, R; Bucci, M; Heinonen, I; Kalliokoski, KK; Kemppainen, J; Knuuti, J; Nuutila, P | 1 |
| Abdallah, Y; Arshad, M; Aslam, M; Becker, L; Grebe, M; Gündüz, D; Härtel, FV; Krieger, U; Noll, T; Piper, HM; Sedding, DG; Voss, RK | 1 |
| Grishin, SN; Kamaliev, RR; Teplov, AY; Ziganshin, AU | 1 |
| Dale, N; Haydon, PG; Schmitt, LI; Sims, RE | 1 |
| Ichinose, TK; Li, C; Minic, Z; O'Leary, DS; Scislo, TJ | 1 |
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| Bu, B; Chen, J; Duan, S; Gao, W; He, Y; Li, Y; Tan, Z; Wang, W; Wu, X; Zeng, L; Zhang, X | 1 |
| Bourgès-Abella, N; Braun, JP; Geffré, A; Granat, F; Trumel, C | 1 |
| Gniel, HM; Martin, RL | 1 |
| Gupta, RC; Kohli, S; Lanfear, DE; Rastogi, S; Sabbah, HN; Wang, M; Zhang, K | 1 |
| Caldarone, CA; Callahan, J; Fu, YY; Kato, H; Leung, CH; Nielsen, JM; Redington, AN; Tropak, MB; Wang, L | 1 |
| Crandall, CG; Gagnon, D; Kenny, GP; McGinn, R; Swift, B | 1 |
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| Eckstein, R; Gall, C; Kraemer, L; Raczat, T; Ringwald, J; Weiss, DR | 1 |
| Joyce, W; Wang, T | 1 |
| Biesiadecki, BJ; Billman, GE; Carnes, CA; Csepe, TA; Fedorenko, O; Fedorov, VV; Glukhov, AV; Györke, S; Hage, LT; Hansen, BJ; Kalyanasundaram, A; Li, N; Lou, Q; Mohler, PJ; Weiss, R | 1 |
| Dai, YB; He, JL; He, LY; Long, Z; Pei, XM; Peng, DY; Shi, XY; Zhang, YC | 1 |
| Ledent, C; Mustafa, SJ; Teng, B; Tilley, S; Zhou, X | 1 |
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| Asakura, M; Asano, Y; Asanuma, H; Ihara, M; Kato, H; Kitakaze, M; Minamino, T; Mochizuki, N; Mori, H; Shinozaki, Y; Sugimachi, M; Yamazaki, S | 1 |
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| Gong, ZH; Huang, B; Jia, YX; Su, RB; Wang, ML; Wang, ZT; Yi, SP; Yu, G; Zhang, FY | 1 |
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| Bottoni, N; Brignole, M; Deharo, JC; Guieu, R; Iori, M; Solari, D | 1 |
| Chovelon, B; Dausse, E; Durand, G; Faure, P; Peyrin, E; Ravelet, C; Toulmé, JJ | 1 |
| Bourgès-Abella, N; Geffré, A; Granat, F; Guerlin, M; Jeunesse, E; Monzali, C; Trumel, C | 1 |
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| Bourgès-Abella, NH; Braun, JD; Geffré, A; Granat, FA; Lucarelli, LA; Trumel, C | 1 |
| Ahmed, W; Alshaikh, A; Amin, R; Bashir, M; Hassan, H; Jeon, S; Jung, D; Musch, M; Ratakonda, S; Sharma, S; Stevens, J | 1 |
| Anastasiadi, RM; Berti, F; Di Tommaso, D; Peressi, M; Pividori, M; Redivo, L; Resmini, M | 1 |
| Bottoni, N; Brignole, M; Deharo, JC; Guieu, R; Iori, M; Rivasi, G; Solari, D; Ungar, A | 1 |
| Abdalla, FH; Bernardes, VM; Braun, JBS; Casali, EA; Castilhos, LG; da Cruz, IBM; de Andrade, CM; de Oliveira, JS; Leal, DBR; Manzoni, AG; Passos, DF; Ruchel, JB | 1 |
| Kim, JW; Lee, JB; Lee, SH | 1 |
| Abriou, C; Barbay, V; Billoir, P; Chrétien, MH; Clavier, T; Fresel, M; Girault, C; Guilbert, A; Le Cam Duchez, V | 1 |
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| Aetesam-Ur-Rahman, M; Bennett, MR; Braganza, DM; Clarke, SC; Clarke, SJ; Giblett, JP; Hoole, SP; Khialani, B; Kyranis, S; West, NEJ; Zhao, TX | 1 |
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37 review(s) available for theophylline and adenosine
| Article | Year |
|---|---|
Adenosine receptors: targets for future drugs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1982 |
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Regulation of cyclic AMP content in normal and malignant brain cells.
Topics: Adenosine; Animals; Brain; Brain Neoplasms; Cerebral Cortex; Cyclic AMP; Hydroxydopamines; Isoproterenol; Kinetics; Nerve Regeneration; Norepinephrine; Papaverine; Phentolamine; Propranolol; Prostaglandins; Rats; Theophylline; Time Factors | 1975 |
[Present status and prospects of platelet inhibitors].
Topics: Adenosine; Aspirin; Blood Platelets; Cyclic AMP; Cyclic GMP; Depression, Chemical; Drug Combinations; Drug Synergism; Humans; Phosphodiesterase Inhibitors; Platelet Aggregation; Prostaglandins E; Serotonin; Theophylline; Thrombosis | 1976 |
Bioassay and pharmacologic evaluation of the adenosine hypothesis.
Topics: Adenosine; Adenosine Monophosphate; Animals; Biological Assay; Coronary Circulation; Hyperemia; Hypoxanthines; Hypoxia; Inosine; Ischemia; Kidney; Muscles; Myocardium; Physical Exertion; Regional Blood Flow; Theophylline | 1977 |
Effects of enprofylline and theophylline may show the role of adenosine.
Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesterified; Gastric Acid; Heart; Humans; Kidney; Kinetics; Lung; Natriuresis; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Seizures; SRS-A; Theophylline; Vasoconstriction; Vasodilation; Xanthines | 1986 |
[Recent data on the mechanism of action of theophylline].
Topics: Adenosine; Calcium; Calmodulin; Humans; Prostaglandin Antagonists; Theophylline | 1988 |
Cardiovascular effects of adenosine in man; possible clinical implications.
Topics: Adenosine; Cardiovascular Diseases; Cardiovascular System; Humans; Hypoxia; Ischemia; Purines; Receptors, Purinergic; Theophylline | 1986 |
[Is adenosine the mediator for the regulation of the coronary circulation and for the effect of coronarodilators? Review].
Topics: Adenosine; Adenosine Triphosphate; Aminohydrolases; Aminophylline; Animals; Calcium; Carbon Dioxide; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs; Hydrogen-Ion Concentration; Hypoxanthines; Hypoxia; Inosine; Nitroglycerin; Oxidative Phosphorylation; Oxygen Consumption; Papaverine; Partial Pressure; Prenylamine; Theophylline; Vasodilator Agents; Verapamil | 1974 |
Cyclic nucleotides in higher plants?
Topics: Adenine; Adenosine; Adenylyl Cyclases; Caffeine; Cyclic AMP; Gibberellins; Phosphoric Diester Hydrolases; Plant Growth Regulators; Plants; Protein Kinases; Theophylline | 1974 |
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
Cardiovascular and renal actions of methylxanthines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 5'-Nucleotidase; Adenosine; Alkaline Phosphatase; Animals; Bacterial Toxins; Blood Pressure; Calcium; Cerebrovascular Circulation; Heart; Heart Rate; Humans; Isoproterenol; Kidney; Myocardial Contraction; Nucleotidases; Phosphodiesterase Inhibitors; Prostaglandin Antagonists; Theophylline; Virulence Factors, Bordetella; Xanthines | 1984 |
[Animal experiments and clinical studies on the role of adenosine in bronchial asthma].
Topics: Adenosine; Adult; Animals; Asthma; Atropine; Basophils; Bronchi; Bronchodilator Agents; Cromolyn Sodium; Double-Blind Method; Female; Hexamethonium Compounds; Humans; Inosine; Lung; Male; Mast Cells; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Urethane; Vagotomy; Xanthines | 1984 |
The use of in vitro brain slices for multidisciplinary studies of synaptic function.
Topics: Adenosine; Animals; Brain; Calcium; Electric Stimulation; Electrophysiology; Guinea Pigs; Hippocampus; Methods; Nerve Tissue Proteins; Neurotransmitter Agents; Phosphorylation; Rats; Synapses; Synaptic Membranes; Synaptic Transmission; Theophylline | 1980 |
Theophylline use in asthma. Some current issues.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Asthma; Bronchi; Cardiac Output; Cyclic AMP; Drug Therapy, Combination; Humans; Kinetics; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic; Stroke Volume; Theophylline | 1984 |
Theophylline actions on adenosine receptors.
Topics: Adenosine; Humans; Lung; Lymphocytes; Mast Cells; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1980 |
[Theophylline: mechanism of action, pharmacokinetics and metabolism].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adult; Calcium; Child; Cyclic AMP; Drug Interactions; Heart Failure; Humans; Kinetics; Liver Diseases; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Respiration Disorders; Theophylline | 1981 |
Role of cyclic nucleotides in the activation-secretion response.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Humans; Mast Cells; Prostaglandins; Protein Kinases; Theophylline | 1984 |
The profile of action of enprofylline, or why adenosine antagonism seems less desirable with xanthine antiasthmatics.
Topics: Adenosine; Animals; Asthma; Bronchi; Cats; Central Nervous System; Chemical Phenomena; Chemistry; Diuresis; Guinea Pigs; Heart; Humans; Lung; Mice; Nausea; Rats; Structure-Activity Relationship; Theophylline; Xanthines | 1983 |
Acetate-induced adenosine mediated effects of ethanol.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Adenosine; Adenosine Monophosphate; Animals; Ethanol; Liver Circulation; Mice; Models, Biological; Motor Activity; Rats; Receptors, Purinergic P1; Theophylline | 1993 |
Therapeutic use of theophylline to antagonize renal effects of adenosine.
Topics: Acute Kidney Injury; Adenosine; Animals; Contrast Media; Erythropoietin; Humans; Kidney; Purinergic P1 Receptor Antagonists; Renal Circulation; Theophylline; Vasoconstriction | 1995 |
Potential role of adenosine antagonist therapy in pathological tremor disorders.
Topics: Adenosine; Adrenergic Antagonists; Brain; Corpus Striatum; Humans; Motor Activity; Motor Skills; Receptors, Purinergic P1; Theophylline; Tremor; Xanthines | 1996 |
ATP-sensitive K+ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Coronary Vessels; Dogs; Enzyme Inhibitors; Glyburide; Hemodynamics; Hyperemia; Nitric Oxide; Nitroarginine; Physical Exertion; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilation | 1998 |
Theophylline and airway inflammation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Administration, Oral; Anti-Inflammatory Agents; Asthma; Biopsy; Bronchi; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Eosinophils; Humans; Leukocyte Count; Lymphocyte Count; Theophylline | 1998 |
Asthma, adenosine, mast cells and theophylline.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Cytokines; Humans; Immunohistochemistry; Lung; Mast Cells; NF-kappa B; Theophylline | 1998 |
Adenosine. An endogenous inhibitor of arachidonic acid release and leukotriene biosynthesis in human neutrophils.
Topics: Adenosine; Animals; Arachidonic Acid; Humans; Leukotriene B4; Neutrophils; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Theophylline | 1999 |
[Pharmacological aspects of mammalian hibernation: central thermoregulation factors in hibernation cycle].
Topics: Adenosine; Animals; Body Temperature; Body Temperature Regulation; Central Nervous System; Cricetinae; Hibernation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Thyrotropin-Releasing Hormone | 2000 |
[Theophylline--contemporary views on cellular mechanism of action].
Topics: Adenosine; Animals; Calcium; Catecholamines; Enzyme Activation; Humans; Isoenzymes; Lung Diseases, Obstructive; Neuropeptides; Phosphoric Diester Hydrolases; Theophylline | 2000 |
[The effects of adenosine, interleukin-1 and theophylline on the expression of A2 adenosine receptor mRNAs in peripheral blood mononuclear cells from asthmatic patients].
Topics: Adenosine; Adolescent; Adult; Asthma; Female; Humans; Interleukin-1; Leukocytes, Mononuclear; Male; Middle Aged; Receptors, Purinergic P1; RNA, Messenger; Theophylline | 2001 |
The case for a role for adenosine in asthma: almost convincing?
Topics: Adenosine; Adenosine Deaminase; Animals; Asthma; Asthma, Exercise-Induced; Bronchial Hyperreactivity; Bronchodilator Agents; Humans; Receptors, Adenosine A2; Theophylline | 2003 |
Role of nitric oxide in the control of coronary resistance in teleosts.
Topics: Adenosine; Animals; Arginine; Coronary Circulation; Electrodes; Fishes; Guanylate Cyclase; Heart; Hypoxia; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Oxygen; Oxygen Consumption; Penicillamine; Theophylline; Time Factors; Trout; Vasodilator Agents | 2005 |
[Coffee and cancer].
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Anticarcinogenic Agents; Caffeine; Cell Transformation, Neoplastic; Coffee; Female; Humans; Lymphocyte Activation; Male; Mice; Mice, Transgenic; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, Adenosine A2; Theobromine; Theophylline | 2008 |
Effects of caffeine and theophylline on coronary hyperemia induced by adenosine or dipyridamole.
Topics: Adenosine; Animals; Caffeine; Coronary Circulation; Coronary Disease; Dipyridamole; Drug Administration Schedule; Drug Interactions; Echocardiography, Doppler; Humans; Hyperemia; Myocardial Perfusion Imaging; Positron-Emission Tomography; Practice Guidelines as Topic; Predictive Value of Tests; Theophylline; Time Factors; Vasodilator Agents | 2009 |
Adenosine receptors and the kidney.
Topics: Acute Kidney Injury; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Glomerular Filtration Rate; Humans; Kidney; Receptor, Adenosine A1; Receptors, Purinergic P1; Renin; Theophylline | 2009 |
Methylxanthines, seizures, and excitotoxicity.
Topics: Adenosine; Animals; Caffeine; Humans; Neurotoxins; Seizures; Theophylline; Xanthines | 2011 |
New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope.
Topics: Accidental Falls; Adenosine; Antihypertensive Agents; Atomoxetine Hydrochloride; Atrioventricular Node; Bradycardia; Cardiac Pacing, Artificial; Decision Trees; Deprescriptions; Fludrocortisone; Humans; Hypotension; Midodrine; Parasympathectomy; Purinergic P1 Receptor Antagonists; Risk Assessment; Sinoatrial Node; Syncope; Theophylline | 2021 |
41 trial(s) available for theophylline and adenosine
| Article | Year |
|---|---|
The use of theophylline, an adenosine antagonist in the prevention of contrast media induced nephrotoxicity.
Topics: Adenosine; Adult; Aged; Contrast Media; Female; Humans; Kidney Diseases; Male; Middle Aged; Theophylline | 1992 |
Pharmacodynamic interactions between infused adenosine and oral theophylline.
Topics: Adenosine; Administration, Oral; Adult; Blood Glucose; Drug Administration Schedule; Drug Interactions; Hemodynamics; Humans; Infusions, Intravenous; Magnesium; Male; Potassium; Pulse; Respiration; Theophylline | 1991 |
Effect of theophylline and dipyridamole on the respiratory response to isocapnic hypoxia in normal human subjects.
Topics: Adenosine; Adult; Carbon Dioxide; Computers; Dipyridamole; Double-Blind Method; Humans; Hypoxia; Male; Respiration; Respiratory System; Spirometry; Theophylline | 1991 |
The effect of theophylline on essential tremor: the possible role of GABA.
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Animals; Cerebral Cortex; Delayed-Action Preparations; Double-Blind Method; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Isoproterenol; Male; Mice; Middle Aged; N-Methylaspartate; Propranolol; Serotonin; Theophylline; Tremor | 1991 |
Adenosine receptor mediated stimulation of ventilation in man.
Topics: Adenosine; Adult; Afferent Pathways; Atropine; Chemoreceptor Cells; Cromolyn Sodium; Dipyridamole; Female; Heart Block; Humans; Hyperventilation; Male; Metoprolol; Middle Aged; Receptors, Purinergic; Respiration; Theophylline | 1989 |
Angina pectoris-like pain provoked by intravenous adenosine in healthy volunteers.
Topics: Adenosine; Adult; Aminophylline; Angina Pectoris; Female; Heart Block; Humans; Male; Theophylline | 1986 |
Contrasting effects of two xanthines, theophylline and enprofylline, on the cardio-respiratory stimulation of infused adenosine in man.
Topics: Adenosine; Adult; Blood Gas Monitoring, Transcutaneous; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Respiration; Theophylline; Xanthines | 1987 |
Specific antagonism of adenosine-induced bronchoconstriction in asthma by oral theophylline.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchi; Bronchodilator Agents; Female; Forced Expiratory Volume; Histamine; Humans; Male; Random Allocation; Theophylline | 1985 |
[Psychotropic effects of a cerebral blood circulation stimulating agent in geriatric patients].
Topics: Adenosine; Administration, Oral; Affective Symptoms; Aged; Analysis of Variance; Cerebrovascular Circulation; Clinical Trials as Topic; Humans; Intelligence Tests; Intracranial Arteriosclerosis; Learning; Memory; Placebos; Rorschach Test; Social Behavior; Theophylline | 1972 |
[Conservative treatment of chronic arterial circulation disorders using a combination of adenosine, theophylline, and sodium nicotinate (ATN)].
Topics: Adenosine; Arterial Occlusive Diseases; Clinical Trials as Topic; Drug Combinations; Humans; Nicotinic Acids; Sodium; Theophylline | 1972 |
Increase in plasma free fatty acids and natriuresis by xanthines may reflect adenosine antagonism.
Topics: Adenosine; Adult; Blood Glucose; Catecholamines; Diuresis; Fatty Acids, Nonesterified; Glucagon; Hemodynamics; Humans; Insulin; Male; Middle Aged; Natriuresis; Renin; Theophylline; Xanthines | 1984 |
Effects of theophylline on renal insufficiency in neonates with respiratory distress syndrome.
Topics: Acute Kidney Injury; Adenosine; Fatal Outcome; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Male; Respiratory Distress Syndrome, Newborn; Theophylline; Vasodilator Agents | 1995 |
Evidence of an adenosine-dependent mechanism in the hypotensive effect of L-arginine in man.
Topics: Adenosine; Adult; Analysis of Variance; Arginine; Blood Pressure; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Humans; Infusions, Intravenous; Leg; Male; Middle Aged; Plethysmography; Regional Blood Flow; Single-Blind Method; Theophylline; Vasodilation | 1995 |
Effects of intravenous theophylline on exercise-induced myocardial ischemia: II. A concentration-dependent phenomenon.
Topics: Adenosine; Aged; Blood Pressure; Cardiac Complexes, Premature; Chronic Disease; Coronary Disease; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Ischemia; Oxygen Consumption; Rest; Systole; Theophylline; Time Factors | 1993 |
Dependency on the rate of change in PaO2 of the ventilatory response to progressive hypoxia.
Topics: Adenosine; Adult; Chemoreceptor Cells; Cross-Over Studies; Humans; Hypoxia; Male; Oxygen; Partial Pressure; Premedication; Pulmonary Gas Exchange; Purinergic P1 Receptor Antagonists; Single-Blind Method; Theophylline; Time Factors | 1995 |
Muscular and cardiac adenosine-induced pain is mediated by A1 receptors.
Topics: Adenosine; Adult; Aged; Analgesics; Angina Pectoris; Dose-Response Relationship, Drug; Female; Humans; Iliac Artery; Infusions, Intra-Arterial; Male; Middle Aged; Muscular Diseases; Pain; Pain Measurement; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
Endogenous adenosine is an antiarrhythmic agent.
Topics: Adenosine; Adult; Dipyridamole; Electrocardiography; Female; Humans; Male; Middle Aged; Tachycardia, Atrioventricular Nodal Reentry; Theophylline | 1995 |
Nephrotoxicity from contrast media: attenuation with theophylline.
Topics: Adenosine; Creatinine; Diatrizoate; Dipyridamole; Humans; Iopamidol; Kidney; Kidney Diseases; Middle Aged; Osmolar Concentration; Receptors, Purinergic P1; Theophylline | 1995 |
Adenosine antagonist theophylline prevents the reduction of glomerular filtration rate after contrast media application.
Topics: Acute Kidney Injury; Adenosine; Aldosterone; Contrast Media; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Iohexol; Male; Middle Aged; Prospective Studies; Renin; Theophylline | 1994 |
Role of endogenous adenosine in hypoxic ventilatory response in humans: a study with dipyridamole.
Topics: Adenosine; Adult; Carbon Dioxide; Dipyridamole; Double-Blind Method; Humans; Hypoxia; Infusions, Intravenous; Male; Oxygen; Respiratory Mechanics; Theophylline | 1994 |
Pretreatment with theophylline does not affect adenosine-induced thallium-201 myocardial imaging.
Topics: Adenosine; Aged; Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiography; Female; Heart; Heart Rate; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Premedication; Radionuclide Imaging; Thallium Radioisotopes; Theophylline | 1993 |
Analgesic effect of bamiphylline on pain induced by intradermal injection of adenosine.
Topics: Adenosine; Adult; Analgesics; Female; Humans; Injections, Intradermal; Male; Pain; Receptors, Purinergic; Sodium Chloride; Theophylline | 1993 |
Efficacy of an adenosine antagonist, theophylline, in essential tremor: comparison with placebo and propranolol.
Topics: Adenosine; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cross-Over Studies; Double-Blind Method; Female; Humans; Infant; Male; Middle Aged; Propranolol; Psychomotor Performance; Theophylline; Tremor | 1995 |
A role for adenosine in coronary vasoregulation in man. Effects of theophylline and enprofylline.
Topics: Adenosine; Adult; Blood Pressure; Coronary Circulation; Double-Blind Method; Exercise; Female; Heart; Heart Rate; Humans; Male; Myocardium; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Theophylline; Vascular Resistance; Vasodilator Agents; Xanthines | 1995 |
Erythropoietin production in healthy volunteers subjected to controlled haemorrhage: evidence against a major role for adenosine.
Topics: Adenosine; Adult; Area Under Curve; Cardiovascular Agents; Creatinine; Dipyridamole; Erythropoietin; Hematocrit; Hemoglobins; Hemorrhage; Humans; Male; Phlebotomy; Phosphodiesterase Inhibitors; Single-Blind Method; Theophylline | 1996 |
The effect of dipyridamole and theophylline on hypercapnic ventilatory responses: the role of adenosine.
Topics: Adenosine; Administration, Oral; Adult; Analysis of Variance; Bronchodilator Agents; Carbon Dioxide; Carotid Body; Dipyridamole; Double-Blind Method; Humans; Hypercapnia; Hyperoxia; Hypoxia; Inhalation; Linear Models; Male; Neurotransmitter Agents; Placebos; Pressure; Respiration; Theophylline; Tidal Volume; Vasodilator Agents | 1997 |
Acute effect of low dose theophylline on the circulatory disturbances of cirrhosis.
Topics: Adenosine; Administration, Oral; Adult; Aged; Hemodynamics; Humans; Liver Cirrhosis; Middle Aged; Renal Circulation; Theophylline; Vasodilator Agents | 1997 |
Erythropoietin production in healthy volunteers subjected to controlled hypobaric hypoxia: further evidence against a role for adenosine.
Topics: Adenosine; Adult; Area Under Curve; Atmosphere Exposure Chambers; Dipyridamole; Erythropoietin; Humans; Hypoxia; Kidney; Male; Placebos; Reference Values; Single-Blind Method; Theophylline | 1997 |
The effect of adenosine on the reduced heart rate response to exercise in the elderly.
Topics: Adenosine; Aged; Aging; Anti-Arrhythmia Agents; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
Comparison between theophylline and spironolactone in the management of cirrhotic ascites: a randomized controlled study.
Topics: Adenosine; Aged; Ascites; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Phosphodiesterase Inhibitors; Spironolactone; Theophylline; Treatment Outcome; Water-Electrolyte Balance | 1998 |
Low-dose theophylline increases urine output in diuretic-dependent critically ill children.
Topics: Adenosine; Adolescent; Analysis of Variance; Animals; Child; Child, Preschool; Critical Illness; Cyclic AMP; Diuretics; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Monitoring; Drug Tolerance; Humans; Infant; Infant, Newborn; Male; Oliguria; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Theophylline; Urine | 1998 |
Prevention of radiocontrast-media-induced nephropathy in patients with pre-existing renal insufficiency by hydration in combination with the adenosine antagonist theophylline.
Topics: Acetylglucosaminidase; Adenosine; Aged; Combined Modality Therapy; Contrast Media; Creatinine; Double-Blind Method; Female; Fluid Therapy; Humans; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Radiography; Theophylline | 1999 |
Effect of theophylline on the warm-up phenomenon.
Topics: Adenosine; Adult; Aged; Angina Pectoris; Coronary Angiography; Coronary Disease; Cross-Over Studies; Double-Blind Method; Electrocardiography; Exercise Test; Female; Humans; Infusions, Intravenous; Ischemic Preconditioning, Myocardial; Male; Middle Aged; Purinergic P1 Receptor Antagonists; Theophylline | 1999 |
Analgesic effects of adenosine in syndrome X are counteracted by theophylline: a double-blind placebo-controlled study.
Topics: Adenosine; Analgesics; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Forearm; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Ischemia; Microvascular Angina; Middle Aged; Muscle, Skeletal; Pain Measurement; Purinergic P1 Receptor Antagonists; Theophylline | 2000 |
Does theophylline really improve acute mountain sickness?
Topics: Acute Disease; Adenosine; Adult; Altitude Sickness; Cross-Over Studies; Double-Blind Method; Humans; Male; Remission Induction; Theophylline | 2001 |
Reduced incidence of radiocontrast-induced nephropathy in ICU patients under theophylline prophylaxis: a prospective comparison to series of patients at similar risk.
Topics: Adenosine; Aged; Contrast Media; Female; Germany; Humans; Incidence; Intensive Care Units; Kidney Diseases; Male; Middle Aged; Phosphodiesterase Inhibitors; Prospective Studies; Risk Factors; Theophylline; Time Factors | 2001 |
Relation between adenosine and T-helper 1/T-helper 2 imbalance in women with preeclampsia.
Topics: Adenosine; Adult; CD4-Positive T-Lymphocytes; Female; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-2; Interleukin-4; Pre-Eclampsia; Pregnancy; Purinergic P1 Receptor Antagonists; Theophylline | 2002 |
Effectiveness of theophylline prophylaxis of renal impairment after coronary angiography in patients with chronic renal insufficiency.
Topics: Adenosine; Aged; Contrast Media; Coronary Angiography; Creatinine; Endpoint Determination; Female; Humans; Iopamidol; Kidney Diseases; Kidney Failure, Chronic; Male; Predictive Value of Tests; Prospective Studies; Regression Analysis; Risk Factors; Theophylline; Treatment Outcome; Vasodilator Agents | 2003 |
Role of endogenous adenosine in atrial fibrillation after coronary artery bypass graft.
Topics: Adenosine; Aged; Atrial Fibrillation; Coronary Artery Bypass; Double-Blind Method; Electrocardiography; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Phosphodiesterase Inhibitors; Prospective Studies; Theophylline | 2004 |
The role of theophylline in prevention of radiocontrast media-induced nephropathy.
Topics: Adenosine; Administration, Oral; Adult; Aged; Biomarkers; Contrast Media; Creatinine; Female; Glomerular Filtration Rate; Humans; Incidence; Infusions, Intravenous; Kidney; Kidney Diseases; Male; Middle Aged; Prospective Studies; Protective Agents; Risk Assessment; Risk Factors; Sodium Bicarbonate; Syria; Theophylline; Treatment Outcome; Urea | 2010 |
Beneficial effects of theophylline infusions in surgical patients with intra-abdominal hypertension.
Topics: Abdomen; Adenosine; APACHE; Biomarkers; Compartment Syndromes; Cytokines; Decompression, Surgical; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Postoperative Complications; Purinergic P1 Receptor Antagonists; Theophylline; Treatment Outcome | 2011 |
1585 other study(ies) available for theophylline and adenosine
| Article | Year |
|---|---|
A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.
Topics: Adenosine; Animals; Dogs; Humans; Molecular Conformation; Molecular Structure; Protein Binding; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines | 1990 |
Binding thermodynamics as a tool to investigate the mechanisms of drug-receptor interactions: thermodynamics of cytoplasmic steroid/nuclear receptors in comparison with membrane receptors.
Topics: Estradiol; Female; Humans; In Vitro Techniques; Male; Metribolone; Pregnenediones; Prostate; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Thermodynamics; Uterus | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Surface Plasmon Resonance Screening to Identify Active and Selective Adenosine Receptor Binding Fragments.
Topics: | 2022 |
Adenosine as a putative transmitter in the cerebral cortex. Studies with potentiators and antagonists.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Animals; Blood Pressure; Caffeine; Cerebral Cortex; Dose-Response Relationship, Drug; Hexobendine; Male; Neurotransmitter Agents; Papaverine; Rats; Receptors, Drug; Structure-Activity Relationship; Theophylline | 1975 |
Isolation of intact megakaryocytes from guinea pig femoral marrow. Successful harvest made possible with inhibitions of platelet aggregation; enrichment achieved with a two-step separation technique.
Topics: Adenosine; Animals; Bucladesine; Centrifugation; Centrifugation, Density Gradient; Guinea Pigs; Hydrogen-Ion Concentration; Maleimides; Megakaryocytes; Ouabain; Theophylline | 1976 |
Cyclic AMP-dependent and independent inhibition of lipolysis by adenosine and decreased pH.
Topics: Acidosis; Adenosine; Adenosine Deaminase; Animals; Cyclic AMP; Drug Interactions; Glycerol; Hydrogen-Ion Concentration; Lipid Mobilization; Male; Norepinephrine; Papaverine; Rats; Theophylline | 1976 |
Pharmacological studies with adenine, adenosine and some phosphorylated derivatives on guinea-pig tracheal muscle.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Propranolol; Quinidine; Theophylline; Trachea | 1976 |
Adenosine, theophylline, and perfusate pH in the isolated, perfused guinea pig heart.
Topics: Adenosine; Animals; Coronary Circulation; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; Heart Rate; Hydrogen-Ion Concentration; Male; Perfusion; Theophylline; Time Factors | 1978 |
Regulation of nerve growth factor content in a neuroblastoma cell line.
Topics: Adenosine; Animals; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Nerve Growth Factors; Neuroblastoma; Neurotransmitter Agents; Prostaglandins E; Theophylline | 1978 |
Alterations in differentiation and pyrimidine pathway enzymes in 5-azacytidine resistant variants of a myoblast line.
Topics: Adenosine; Animals; Aspartate Carbamoyltransferase; Azacitidine; Azaguanine; Bromodeoxyuridine; Cell Differentiation; Cell Fusion; Cell Line; Cytarabine; Cytidine Deaminase; Drug Resistance; Genetic Variation; Muscles; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Ouabain; Phosphotransferases; Rats; Theophylline; Thymidine; Uridine; Uridine Kinase | 1977 |
Adenosine receptor on human basophils: modulation of histamine release.
Topics: Adenosine; Adenylyl Cyclases; Basophils; Binding Sites; Cyclic AMP; Dose-Response Relationship, Immunologic; Histamine Release; Humans; Theophylline | 1979 |
Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Brain; Caffeine; Cerebral Cortex; Male; Neural Inhibition; Neurons; Rats; Synapses; Synaptic Transmission; Theophylline | 1979 |
1-Isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic AMP in brain slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Brain; Cyclic AMP; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Male; Norepinephrine; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1979 |
[The effect of hypoxia on the branchial vascular system of the perfused trout head].
Topics: Adenosine; Animals; Gills; Hypoxia; Perfusion; Regional Blood Flow; Salmonidae; Theophylline; Trout; Vascular Resistance | 1977 |
Effects of adenosine deaminase on cyclic adenosine monophosphate accumulation, lipolysis, and glucose metabolism of fat cells.
Topics: Adenosine; Adipose Tissue; Animals; Anti-Bacterial Agents; Cyclic AMP; Glucose; Glycerol; Insulin; Kinetics; Lipid Mobilization; Norepinephrine; Nucleoside Deaminases; Rats; Theophylline; Time Factors; Xanthines | 1975 |
Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Astrocytoma; Catecholamines; Cells, Cultured; Cyclic AMP; Dipyridamole; Dopamine; Drug Interactions; Epinephrine; Humans; Isoproterenol; Norepinephrine; Propranolol; Prostaglandin Antagonists; Prostaglandins; Structure-Activity Relationship; Theophylline; Time Factors; Tritium | 1975 |
Adenosine release from fat cells: effect on cyclic AMP levels and hormone actions.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Cyclic AMP; Glycerol; In Vitro Techniques; Insulin; Lipid Mobilization; Norepinephrine; Rats; Theophylline; Time Factors | 1975 |
Regulation of theta-antigen expression by agents altering cyclic AMP level and by thymic factor.
Topics: Acetylcholine; Adenosine; Animals; Antilymphocyte Serum; Azathioprine; Bucladesine; Cyclic AMP; Cyclic GMP; Cytotoxicity Tests, Immunologic; Immune Adherence Reaction; Isoantigens; Lymphocytes; Mice; Mice, Inbred AKR; Mice, Nude; Prostaglandins; Radiation Chimera; Spleen; Theophylline; Thymectomy; Thymosin; Thymus Extracts | 1975 |
Comparative effects of adenosine and adenine and guanine nucleotides on drug biotransformation in rats.
Topics: Adenine; Adenosine; Aniline Compounds; Animals; Biotransformation; Bucladesine; Cyclic AMP; Guanine Nucleotides; Hexobarbital; In Vitro Techniques; Liver; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Theophylline | 1975 |
2-Chloroadenosine-dependent elevation of adenosine 3',5'-cyclic monophosphate levels in rat caudate nucleus slices.
Topics: Adenosine; Animals; Caudate Nucleus; Cyclic AMP; Deoxyadenosines; Dopamine; Dose-Response Relationship, Drug; Etazolate; In Vitro Techniques; Male; Norepinephrine; Phosphodiesterase Inhibitors; Rats; Theophylline; Xanthines | 1975 |
Characterization of the metabolism of exogenous cyclic AMP by perfused rat heart and incubated prepubertal rat ovary.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Female; Metabolic Clearance Rate; Myocardium; Ovary; Phosphoric Diester Hydrolases; Rats; Theophylline; Time Factors | 1975 |
Adenosine, AMP, cyclic AMP, theophylline and the action and production of erythropoietin.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Cyclic AMP; Erythropoiesis; Erythropoietin; Female; Male; Mice; Rats; Species Specificity; Theophylline; Time Factors | 1975 |
The stimulation of the phospholipase A2-acylation system of synaptic membranes of brain by cyclic nucleotides.
Topics: Acylation; Adenosine; Animals; Brain; Calcium Chloride; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; Magnesium; Norepinephrine; Nucleotides, Cyclic; Oleic Acids; Phosphatidylcholines; Phospholipases; Synaptic Membranes; Theophylline | 1975 |
Effect of adenosine deaminase inhibition upon human lymphocyte blastogenesis.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Bucladesine; Cells, Cultured; Concanavalin A; Cyclic AMP; Humans; Isoproterenol; Lectins; Leucine; Lymphocytes; Norepinephrine; Nucleoside Deaminases; Theophylline; Thymidine; Uridine | 1976 |
Mode of action of Vibrio cholerae enterotoxin in cultured adrenal tumor cells.
Topics: Adenosine; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Bacterial Proteins; Bucladesine; Cells, Cultured; Cyclic AMP; Enterotoxins; Gangliosides; Immune Sera; Neoplasms, Experimental; Steroids; Theophylline; Vibrio cholerae | 1976 |
Neuroblastoma cell adenylate cyclase: direct activation by adenosine and prostaglandins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenylyl Cyclases; Cell Line; Cyclic GMP; Dopamine; Isoproterenol; Kinetics; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Papaverine; Prostaglandins E; Prostaglandins F; Theophylline | 1976 |
Cyclic 3',5'-adenosine monophosphate and accessory sex organ responses.
Topics: Adenosine; Adenylyl Cyclases; Androgens; Animals; Carbohydrate Metabolism; Cyclic AMP; Drug Synergism; Estrogens; Female; Male; Models, Biological; Prostate; Rats; Seminal Vesicles; Theophylline; Uterus | 1975 |
Stimulation of ribonuclease activity and its isoenzymes in germinating seeds of cowpea (Vigna sinensis) by gibberellic acid and adenosine-3',5-cyclic monophosphate.
Topics: Adenine; Adenine Nucleotides; Adenosine; Cyclic AMP; Cycloheximide; Dactinomycin; Gibberellins; Isoenzymes; Plant Proteins; Ribonucleases; RNA; Seeds; Theophylline | 1976 |
Adenosine-mediated stimulation of bone cell adenylate cyclase activity.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Bone and Bones; Cyclic AMP; Enzyme Activation; Kinetics; Magnesium; Rats; Theophylline | 1976 |
Adenosine inhibition of isolated rabbit ileum and antagonism by theophylline.
Topics: Adenosine; Animals; Binding Sites; Cyclic AMP; Depression, Chemical; Ileum; In Vitro Techniques; Male; Muscle Contraction; Rabbits; Structure-Activity Relationship; Theophylline; Xanthines | 1976 |
Differentiation induced by cyclic AMP in undifferentiated cells of early chick embryo in vitro.
Topics: Adenosine; Animals; Bucladesine; Cell Differentiation; Chick Embryo; Cyclic AMP; Heart; Myocardial Contraction; Myofibrils; RNA; Theophylline | 1976 |
Adenosine and adenine nucleotides stimulation of skin (epidermal) adenylate cyclase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Enzyme Activation; Inosine; Kinetics; Papaverine; Skin; Swine; Theophylline | 1976 |
Adenosine promoted accumulation of adenosine 3',5'-monophosphate in rabbit vagus nerve.
Topics: Adenosine; Animals; Cyclic AMP; Myelin Sheath; Rabbits; Theophylline; Vagus Nerve | 1976 |
A role of cyclic nucleotides in neuromuscular transmission.
Topics: Adenosine; Alloxan; Animals; Axons; Bucladesine; Cats; Cyclic AMP; Dithionitrobenzoic Acid; Electric Stimulation; Fluorides; Gallopamil; Imidazoles; Muscle Contraction; Muscle Denervation; Muscles; Nerve Endings; Neuromuscular Junction; Prostaglandins E; Synaptic Transmission; Theophylline; Verapamil | 1976 |
Behavioral activity and accumulation of cyclic AMP in brain slices of strains of mice.
Topics: Adenosine; Animals; Avoidance Learning; Brain; Cyclic AMP; Female; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Motor Activity; Norepinephrine; Theophylline | 1976 |
The influence of prostaglandin G2 on platelet ultrastructure and platelet secretion.
Topics: Adenosine; Blood Platelets; Bucladesine; Calcimycin; Cyclic GMP; Edetic Acid; Ethylmaleimide; Humans; Phorbols; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Serotonin; Theophylline | 1977 |
Effects of adenosine and related compounds on adenylate cyclase and cyclic AMP levels in smooth muscle.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Drug Interactions; Epinephrine; In Vitro Techniques; Isoproterenol; Muscle, Smooth; Rabbits; Theophylline; Xanthines | 1977 |
Effects of diaminopropionate, deoxyadenosine, and theophylline on stimulated formation of cyclic AMP and GMP by depolarizing agents in slices of guinea-pig cerebral cortex.
Topics: Adenosine; Alanine; Amino Acids, Diamino; Animals; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cysteine; Deoxyadenosines; Glutamates; Guinea Pigs; Histamine; In Vitro Techniques; Male; Nucleotides, Cyclic; Ouabain; Potassium; Theophylline; Veratridine; Xanthines | 1977 |
Adenosine-sensitive adenylate cyclase in rat striatal homogenates.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Caffeine; Corpus Striatum; Cyclic AMP; Kinetics; Male; Rats; Structure-Activity Relationship; Theophylline; Xanthines | 1977 |
Effects of ACTH, adenyl compounds, and methylxanthines on goldfish erythrophores in culture.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adrenocorticotropic Hormone; Animals; Bucladesine; Caffeine; Cells, Cultured; Chromatophores; Cyclic AMP; Cytoplasmic Granules; Dose-Response Relationship, Drug; Goldfish; Kinetics; Microscopy, Phase-Contrast; Pigments, Biological; Theophylline; Xanthines | 1977 |
Effects of db-cAMP and theophylline on Concanavalin A binding site distribution on transformed and protease-treated cell lines.
Topics: Adenosine; Adenosine Monophosphate; Bucladesine; Butyrates; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Concanavalin A; Cyclic GMP; Receptors, Concanavalin A; Receptors, Drug; Theophylline; Trypsin | 1977 |
Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors.
Topics: Adenosine; Blood Platelets; Caffeine; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dipyridamole; Humans; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phthalazines; Platelet Aggregation; Theophylline | 1977 |
Properties of human erythrocyte phosphatidylinositol kinase and inhibition by adenosine, ADP and related compounds.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Caffeine; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotides; Humans; Kinetics; Mercaptoethanol; Phosphatidylinositols; Phosphotransferases; Polyethylene Glycols; Theophylline | 1977 |
Elevation of guanosine 3',5'-monophosphate level by adenosine in cerebellar slices of guinea pig.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cerebellum; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Papaverine; Phosphodiesterase Inhibitors; Theophylline; Xanthines | 1977 |
The accumulation of cyclic AMP and cyclic GMP in guinea pig brain slices. Effect of calcium ions, norepinephrine and adenosine.
Topics: Adenosine; Animals; Brain; Calcium; Cerebellum; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Mice; Norepinephrine; Organ Specificity; Rats; Species Specificity; Theophylline | 1977 |
Experimental cerebrovascular disorders: effects of papaverine and theophylline.
Topics: Adenosine; Animals; Cerebrospinal Fluid Proteins; Cerebrovascular Disorders; Cyclic AMP; Drug Evaluation, Preclinical; Female; Male; Papaverine; Rabbits; Theophylline | 1977 |
Effect of cyclic-AMP and other compounds on electrical activity of neurohaemal tissue in Carausius.
Topics: Action Potentials; Adenosine; Animals; Bucladesine; Caffeine; Cyclic AMP; Histamine; Insecta; Nervous System; Norepinephrine; Theophylline | 1977 |
Presynaptic inhibitory actions of adenine nucleotides and adenosine on neurotransmission in the rat vas deferens.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Atropine; Depression, Chemical; Dipyridamole; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Rats; Synapses; Synaptic Transmission; Theophylline; Vas Deferens | 1977 |
Control of cyclic adenosine 3':5'-monophosphate-elevating effect of adenosine in C-1300 murine neuroblastoma in tissue culture.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Cell Line; Cyclic AMP; Drug Interactions; Guanosine; Inosine; Neuroblastoma; Prostaglandins E; Theophylline | 1977 |
Effects of isoprenaline on the time course of the cyclic AMP level in rat uterus.
Topics: Adenosine; Animals; Catechols; Corticosterone; Cyclic AMP; Dipyridamole; Female; Guanosine Triphosphate; Isoproterenol; Muscle Relaxation; Myometrium; Puromycin; Rats; Theophylline; Uterus | 1978 |
Influence of cyclic AMP on DNA synthesis in slices of regenerating rat liver.
Topics: Adenosine; Animals; Cyclic AMP; DNA; In Vitro Techniques; Liver; Liver Regeneration; Male; Rats; Theophylline; Thymidine | 1978 |
Antagonistic effects of theophylline and adenosine on adrenergic neuroeffector transmission in the rabbit kidney.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenergic Fibers; Animals; Electric Stimulation; Female; Kidney; Male; Norepinephrine; Phosphodiesterase Inhibitors; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Vasoconstriction | 1978 |
Evidence for the cell surface locus of presynaptic purine nucleotide receptors in the guinea-pig ileum.
Topics: Adenosine; Animals; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purine Nucleotides; Receptors, Neurotransmitter; Theophylline | 1978 |
Biochemical and electropharmaceutical studies with tricyclic antidepressants in rat and guinea-pig cerebral cortex.
Topics: Adenosine; Animals; Antidepressive Agents, Tricyclic; Brain; Cyclic AMP; Dipyridamole; Drug Interactions; Guinea Pigs; In Vitro Techniques; Iontophoresis; Male; Neurons; Theophylline | 1978 |
Effects of adenosine on neurally mediated norepinephrine release from the cat spleen.
Topics: Adenosine; Animals; Cats; In Vitro Techniques; Norepinephrine; Spleen; Synaptic Transmission; Theophylline | 1979 |
Mechanisms of depression of neuromuscular transmission by ATP and adenosine.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Anura; Calcium; Cyclic AMP; Female; Imidazoles; In Vitro Techniques; Male; Neural Inhibition; Neuromuscular Junction; Rats; Synaptic Transmission; Theophylline | 1978 |
The action of adenosine on steroidogenesis in isolated rat adrenocortical cells.
Topics: Adenine Nucleotides; Adenosine; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Rats; Steroids; Theophylline | 1978 |
Presynaptic inhibitory actions of 2-substituted adenosine derivatives on neurotransmission in rat vas deferens: effects of inhibitors of adenosine uptake and deamination.
Topics: Adenosine; Animals; Atropine; Coformycin; Deamination; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenoxybenzamine; Rats; Synaptic Transmission; Theophylline; Vas Deferens | 1979 |
Uptake and release of adenosine in isolated rat fat cells.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adipose Tissue; Animals; Cyclic AMP; Isoproterenol; Lipid Metabolism; Methoxamine; Norepinephrine; Nucleotidases; Papaverine; Rats; Theophylline | 1979 |
Effect of lipolytic agents on adenosine and AMP formation by fat cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adipose Tissue; Allopurinol; Animals; Cyclic AMP; Female; In Vitro Techniques; Norepinephrine; Oleic Acids; Rats; Theophylline; Xanthine Dehydrogenase | 1979 |
The effects of adenosine and adenine nucleotides on the guinea-pig vas deferens: evidence for existence of purinergic receptors.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Isatin; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Pyridines; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Theophylline; Vas Deferens | 1979 |
Stereospecific influence of oxazepam hemisuccinate on cyclic AMP accumulation elicited by adenosine in cerebral cortical slices.
Topics: Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Oxazepam; Rats; Stereoisomerism; Theophylline | 1979 |
Hormone-like action of adenosine in mouse thymocytes and splenocytes: Evidence for the existence of membrane adenosine receptors coupled to adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Male; Mice; Receptors, Drug; Spleen; Theophylline; Thymus Gland | 1979 |
Evidence for two adenine derivative receptors in rat ileum which are not involved in the nonadrenergic, noncholinergic response.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Electric Stimulation; Ileum; In Vitro Techniques; Male; Nicotine; Parasympathetic Nervous System; Rats; Receptors, Cell Surface; Sympathetic Nervous System; Theophylline | 1979 |
Effect of adenosine on adrenergic neurotransmission in the superfused rat portal vein.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Male; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Rats; Sympathetic Nervous System; Synaptic Transmission; Theophylline | 1979 |
Inhibition of cardiac sympathetic neurotransmission by adenosine.
Topics: Adenosine; Animals; Depression, Chemical; Dogs; Heart; Heart Rate; Injections, Intravenous; Sympathetic Nervous System; Synaptic Transmission; Theophylline | 1979 |
On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; Guinea Pigs; Hydrolysis; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaverine; Theophylline; Trachea | 1979 |
Comparison of the effects of biogenic amines on cyclic GMP and cycle AMP levels in mouse cerebellum in vitro.
Topics: Adenosine; Animals; Biogenic Amines; Brain Chemistry; Calcium; Cerebellum; Culture Media; Cyclic AMP; Cyclic GMP; Dopamine; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Histamine; Male; Mice; Neuromuscular Depolarizing Agents; Norepinephrine; Potassium; Receptors, Adrenergic; Serotonin; Theophylline; Tyrosine | 1975 |
Regulation of cyclic adenosine 3',5'-monophosphate levels in guinea-pig cerebral cortex by interaction of alpha adrenergic and adenosine receptor activity.
Topics: Adenosine; Animals; Brain Chemistry; Cerebral Cortex; Cyclic AMP; Diphenhydramine; Dopamine; Epinephrine; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Isoproterenol; Magnesium; Male; Norepinephrine; Phentolamine; Propranolol; Receptors, Adrenergic; Receptors, Drug; Theophylline; Tritium | 1975 |
Adenosine 3',5'-monophosphate in bovine superior cervical ganglion: effect of high extracellular potassium.
Topics: Adenosine; Animals; Cattle; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Ganglia; Ganglia, Spinal; Ganglionic Blockers; Histamine H1 Antagonists; In Vitro Techniques; Norepinephrine; Parasympatholytics; Phosphodiesterase Inhibitors; Potassium; Stimulation, Chemical; Sympatholytics; Synaptic Transmission; Theophylline | 1975 |
Adenylate cyclase from synchronized neuroblastoma cells: responsiveness to prostaglandin E1, adenosine, and dopamine during the cell cycle.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Division; Cell Line; DNA Replication; Dopamine; Enzyme Activation; Fluphenazine; Kinetics; Mice; Neuroblastoma; Prostaglandins E; Theophylline | 1977 |
Action of adenosine on chloride active transport of isolated frog cornea.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Anura; Biological Transport, Active; Chlorides; Cornea; Epinephrine; Polyphloretin Phosphate; Propranolol; Rana catesbeiana; Ribose; Theophylline | 1979 |
Restoration by adenosine and theophylline of glucose-induced insulin responsiveness in newborn rats.
Topics: Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Glucose; Insulin; Islets of Langerhans; Rats; Theophylline | 1977 |
Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Adenosine Triphosphate; Amines; Animals; Female; Guinea Pigs; Indomethacin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Parasympatholytics; Propranolol; Tetrodotoxin; Theophylline; Urinary Bladder | 1979 |
Effects of cholinoceptor blocking drugs, adrenoceptor stimulants, and calcium antagonists on the transmurally stimulated guinea-pig urinary bladder in vitro and in vivo.
Topics: Adenosine; Animals; Calcium; Electric Stimulation; Female; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Propranolol; Sympathomimetics; Theophylline; Urinary Bladder | 1979 |
Adenosine modulation of synaptosomal dopamine release.
Topics: Adenosine; Adenosine Deaminase; Animals; Corpus Striatum; Dopamine; Kinetics; Male; Potassium Chloride; Rats; Synaptosomes; Theophylline | 1979 |
Purine effects at the neuromuscular junction and their modification by theophylline, imidazole and verapamil.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Female; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Junction; Norepinephrine; Ouabain; Purine Nucleosides; Purine Nucleotides; Rats; Theophylline; Verapamil | 1979 |
Evidence from bioassay studies indicating a role for adenosine in cardiac ischemic and hypoxic dilation in the dog.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Biological Assay; Coronary Circulation; Coronary Disease; Dogs; Hyperemia; Hypoxia; Kidney; Methods; Perfusion; Theophylline; Vascular Resistance | 1979 |
Relaxation of guinea-pig fundic strip by adenosine, adenosine triphosphate and electrical stimulation: lack of antagonism by theophylline or ATP treatment.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Stomach; Theophylline | 1979 |
Theophylline antagonizes flurazepam-induced depression of cerebral cortical neurons.
Topics: Adenosine; Animals; Cerebral Cortex; Flurazepam; Male; Neurons; Rats; Theophylline | 1979 |
Inhibition of immune cell function by adenosine: biochemical studies.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Animals; Cytotoxicity, Immunologic; Homocysteine; Imidazoles; Lymphocytes; Methionine; Mice; S-Adenosylmethionine; Theophylline; Uridine | 1979 |
[Effects of adenosine compounds of the vascular bed and effects of dilazep, theophylline, and indomethacin on blood flow changes of the postocclusive renal vessels].
Topics: Adenine Nucleotides; Adenosine; Angiotensin II; Animals; Azepines; Blood Flow Velocity; Blood Vessels; Dilazep; Dogs; Drug Synergism; Female; Femoral Artery; Indomethacin; Kidney; Ligation; Male; Mesenteric Arteries; Norepinephrine; Renal Artery; Theophylline | 1977 |
Tissue content of adenosine, inosine and hypoxanthine in the rat kidney after ischemia and postischemic recirculation.
Topics: Adenosine; Animals; Hypoxanthines; Inosine; Ischemia; Kidney; Rats; Regional Blood Flow; Theophylline; Time Factors | 1977 |
Interaction of adenosine and its phosphorylated derivatives with putative purinergic receptors in the gill vascular bed of rainbow trout.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Animals; Dipyridamole; Gills; Hemodynamics; In Vitro Techniques; Receptors, Drug; Salmonidae; Theophylline; Trout | 1979 |
Action of phenylisopropyl-adenosine (PIA) on the synthesis of corticosterone in rats.
Topics: Adenosine; Adrenal Glands; Animals; Corticosterone; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Theophylline | 1977 |
Relaxations of guinea-pig fundic strip by adenosine, adenine nucleotides and electrical stimulation: antagonsism by theophylline and desensitization to adenosine and its derivatives.
Topics: Adenine Nucleotides; Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Rats; Reserpine; Stomach; Theophylline | 1977 |
Effects of aminophylline, proxyphylline and a proxyphylline-Melilotus extract-rutin mixture (theoesberiven) on the heart and the coronary circulation.
Topics: Adenosine; Aminophylline; Animals; Blood Volume; Cardiac Output; Coronary Circulation; Coumarins; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Oxygen; Oxygen Consumption; Plant Extracts; Rutin; Stimulation, Chemical; Theophylline | 1977 |
Activation of adenylate cyclase from rat striatum and tuberculum olfactorium by adenosine.
Topics: Adenosine; Adenylyl Cyclases; Animals; Corpus Striatum; Dipyridamole; Dopamine; Enzyme Activation; Male; Olfactory Bulb; Papaverine; Rats; Subcellular Fractions; Theophylline; Xanthines | 1977 |
Effect of adenosine, adenosine analogues and drugs inhibiting adenosine inactivation on lipolysis in rat fat cells.
Topics: Adenosine; Adipose Tissue; Animals; Lipid Metabolism; Male; Norepinephrine; Nucleotides; Rats; Theophylline | 1978 |
Adenosine modulates depolarization-induced release of 3H-noradrenaline from slices of rat brain neocortex.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Theophylline | 1978 |
Role of cyclic nucleotides in adenosine-mediated regulation of coronary flow.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cattle; Coronary Circulation; Coronary Vessels; Digitonin; Drug Interactions; In Vitro Techniques; Isoproterenol; Nucleotides, Cyclic; Papaverine; Phosphatidylserines; Sodium Fluoride; Sotalol; Theophylline; Time Factors | 1978 |
The development of tachyphylaxis to electrical stimulation in guinea-pig ileal longitudinal muscles and the possible participation of adenosine and adenine nucleotides.
Topics: Acetylcholine; Adenine; Adenine Nucleotides; Adenosine; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Tachyphylaxis; Theophylline | 1978 |
Antilipolytic effect of adenosine in isolated perifused fat cells.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Glycerol; In Vitro Techniques; Male; Norepinephrine; Perfusion; Rats; Theophylline | 1978 |
[Adenylate cyclase in synchronized neuroblastoma cells: enzyme response during the cell cycle].
Topics: Adenosine; Adenylyl Cyclases; Cell Division; Cell Line; Dopamine; Fluphenazine; Neuroblastoma; Prostaglandins E; Theophylline; Time Factors | 1976 |
Reduction of exercise dilation by theophylline.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; In Vitro Techniques; Muscles; Physical Exertion; Theophylline; Vasomotor System | 1977 |
Antagonism by methylxanthines of purine nucleotide-and dipyridamole-induced inhibition of peristaltic activity of the guinea pig ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Aminophylline; Animals; Dipyridamole; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Hydroxydopamines; Ileum; In Vitro Techniques; Male; Parasympatholytics; Peristalsis; Purine Nucleotides; Reserpine; Theophylline; Xanthines | 1977 |
Adenosine-sensitive adenylate cyclase in rat striatal homogenates and its relationship to dopamine- and Ca2+-sensitive adenylate cyclases.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Receptors, Drug; Theophylline; Xanthines | 1977 |
Binding of cytochalasin B to hexose transport sites on human spermatozoa and inhibition of binding by purines.
Topics: Adenosine; Binding, Competitive; Biological Transport; Cell Membrane; Cytochalasin B; Dose-Response Relationship, Drug; Fructose; Glucose; Hexoses; Humans; Male; Purines; Sperm Motility; Spermatozoa; Theophylline | 1977 |
Coronary vasoactivity of adenosine covalently linked to polylysine.
Topics: Adenosine; Animals; Blood Pressure; Cells, Cultured; Chickens; Coronary Circulation; Dogs; Erythrocytes; Fibroblasts; Heart Rate; Muscles; Oligopeptides; Peptides; Polylysine; Theophylline; Vasodilator Agents | 1977 |
Regulation of adenylate cyclase from cultured human cell lines by adenosine.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Cell Line; Enzyme Activation; Epinephrine; Guanine Nucleotides; Humans; Kinetics; Magnesium; Propranolol; Theophylline; Time Factors | 1976 |
The dilatatory action of adenosine on pial arteries of cats and its inhibition by theophylline.
Topics: Adenosine; Animals; Arteries; Cats; Female; Male; Muscle Tonus; Muscle, Smooth; Pia Mater; Theophylline; Vascular Resistance | 1976 |
The inhibitory effect of adenosine and related nucleotides on the release of acetylcholine.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Cerebral Cortex; Cholecystokinin; Electric Stimulation; Guinea Pigs; Ileum; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Ouabain; Rats; Theophylline; Xylazine | 1976 |
Influence of adenosine and lowered cerebral blood flow on the cerebrovascular effects of theophylline.
Topics: Adenosine; Animals; Blood Pressure; Body Temperature; Cerebrovascular Circulation; Dogs; Drug Interactions; In Vitro Techniques; Perfusion; Theophylline; Time Factors; Vascular Resistance | 1975 |
The effect of ATP and related compounds on spontaneous mechanical activity in the rat portal vein.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Depression, Chemical; Drug Interactions; Female; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Portal Vein; Rats; Stimulation, Chemical; Theophylline; Vascular Resistance | 1975 |
Renal effects of adenosine and their inhibition by theophylline in dogs.
Topics: Adenosine; Animals; Blood Pressure; Diuresis; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Injections, Intra-Arterial; Kidney; Male; Regional Blood Flow; Renal Artery; Sodium; Theophylline; Vascular Resistance | 1975 |
Mouse neuroblastoma adenylate cyclase. Adenosine and adenosine analogues as potent effectors of adenylate cyclase activity.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Clone Cells; Cytidine; Guanine; Guanosine; Kinetics; Mice; Neuroblastoma; Phosphorus Radioisotopes; Prostaglandins E; Ribose; Theophylline; Tolazoline; Uridine; Yohimbine | 1975 |
The effect of metoclopramide on inhibition induced by purine nucleotides, noradrenaline, and theophylline ethylenediamine on intestinal muscle and on peristalsis in vitro.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Duodenum; Ethylenediamines; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Metoclopramide; Muscle, Smooth; Norepinephrine; Organ Specificity; Peristalsis; Purine Nucleotides; Rabbits; Rats; Species Specificity; Theophylline | 1975 |
Coronary responses to dilating substances and competitive inhibition by theophylline in the isolated perfused guinea pig heart.
Topics: Adenine Nucleotides; Adenosine; Animals; Calcium; Coronary Circulation; Dipyridamole; Dose-Response Relationship, Drug; Drug Antagonism; Gallopamil; Guinea Pigs; Heart; In Vitro Techniques; Papaverine; Potassium; Temperature; Theophylline; Vasodilator Agents | 1975 |
Proceedings: Effects of adenosine and theophylline upon cerebral resistance to flow.
Topics: Adenosine; Animals; Cats; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Theophylline; Vascular Resistance | 1975 |
Effect of adenosine on myocardial oxygen balance.
Topics: Adenosine; Adenosine Monophosphate; Animals; Coronary Circulation; Dogs; Female; Heart Rate; Hypoxanthines; Inosine; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Theophylline; Ventricular Fibrillation | 1976 |
Inhibition of acetylcholine release from cholinergic nerves by adenosine, adenine nucleotides and morphine: antagonism by theophylline.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Male; Morphine; Muscle Contraction; Neurons; Parasympathetic Nervous System; Theophylline | 1976 |
Evidence for an adenosine receptor on the surface of dog coronary myocytes.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Muscle, Smooth; Oligosaccharides; Receptors, Adrenergic; Theophylline | 1976 |
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Caffeine; Electroencephalography; Male; Parasympatholytics; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1992 |
Adenosine-induced bronchoconstriction in an allergic rabbit model: antagonism by theophylline aerosol.
Topics: Adenosine; Aerosols; Anesthesia; Animals; Asthma; Bronchial Hyperreactivity; Histamine; Pollen; Rabbits; Respiratory Hypersensitivity; Theophylline | 1992 |
Plasma adenosine and cardiovascular responses to dipyridamole in fetal sheep.
Topics: Adenosine; Animals; Blood Pressure; Dipyridamole; Female; Fetus; Gestational Age; Heart Rate, Fetal; Hypoxia; Pregnancy; Purinergic Antagonists; Sheep; Theophylline | 1992 |
Adenosine-dependent enhancement by methylxanthines of excitatory synaptic transmission in hippocampus of rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Theophylline | 1992 |
Endogenous adenosine blunts beta-adrenoceptor-mediated inotropic response in hypoperfused canine myocardium.
Topics: Adenosine; Animals; Coronary Disease; Dogs; Heart; Isoproterenol; Myocardial Contraction; Prazosin; Receptors, Adrenergic, beta; Theophylline | 1992 |
Purinoceptor-mediated modulation by endogenous and exogenous agonists of stimulation-evoked [3H]noradrenaline release on rat iris.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Iris; Male; Norepinephrine; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synaptic Transmission; Theophylline; Xanthines | 1992 |
Non-eicosanoid functions of essential fatty acids: regulation of adenosine-related functions in cultured neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Calcium; Colforsin; Cyclic AMP; Eicosanoids; Fatty Acids, Essential; Fatty Acids, Unsaturated; Neuroblastoma; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured | 1992 |
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Muscle, Smooth; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Type C Phospholipases; Virulence Factors, Bordetella | 1992 |
Molecular cloning and expression of an adenosine A2b receptor from human brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; DNA; Gene Expression; Humans; Molecular Sequence Data; Receptors, Purinergic; Sequence Homology, Nucleic Acid; Theophylline; Transfection | 1992 |
Pharmacological characterization of adenosine A1 and A2 receptors in the bladder: evidence for a modulatory adenosine tone regulating non-adrenergic non-cholinergic neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Autonomic Nervous System; Dipyridamole; Electric Stimulation; Mice; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Receptors, Purinergic; Synaptic Transmission; Theophylline; Urinary Bladder | 1992 |
Effect of nucleosides and nucleotides and the relationship between cellular adenosine 3':5'-cyclic monophosphate (cyclic AMP) and germ tube formation in Candida albicans.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine Nucleotides; Adenosine; Caffeine; Candida albicans; Cyclic AMP; Theophylline | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; Dipyridamole; Electric Stimulation; In Vitro Techniques; Magnesium; Male; Mice; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Purinergic Antagonists; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline; Tritium; Tubocurarine; Xanthines | 1992 |
Involvement of adenosine in antinociception produced by spinal or supraspinal receptor-selective opioid agonists: dissociation from gastrointestinal effects in mice.
Topics: Adenosine; Analgesia; Animals; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastric Emptying; Gastrointestinal Motility; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Opioid; Spinal Cord; Theophylline | 1992 |
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens, CD; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Humans; Macrophage-1 Antigen; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1992 |
Further characterization of the protective effect of 8-cyclopentyl-1,3-dipropylxanthine on glycerol-induced acute renal failure in the rat.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acute Kidney Injury; Adenosine; Animals; Creatinine; Glycerol; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation; Theophylline; Urea | 1992 |
Adenosine-theophylline interactions on the lipolytic response to beta-adrenergic agonists in porcine adipose tissue.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Drug Interactions; Lipolysis; Male; Swine; Theophylline | 1992 |
Changes in neurotransmitter sensitivity in the mouse neocortical slice following propranolol and theophylline administration.
Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Isoproterenol; Male; Mice; N-Methylaspartate; Propranolol; Serotonin; Theophylline | 1991 |
Adenosine-induced bronchoconstriction of isolated lung and trachea from sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Immunization; In Vitro Techniques; Lung; Ovalbumin; Perfusion; Theophylline; Trachea | 1992 |
Electrophysiological actions of acetate, a metabolite of ethanol, on hippocampal dentate granule neurons: interactions with adenosine.
Topics: Acetates; Adenosine; Animals; Electrophysiology; Ethanol; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic; Theophylline | 1992 |
Relative agonist potencies of C2-substituted analogues of adenosine: evidence for adenosine A2B receptors in the guinea pig aorta.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Male; Muscle, Smooth, Vascular; Phenethylamines; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1992 |
Antidiuretic effects of purinoceptor agonists injected into the hypothalamic paraventricular nucleus of water-loaded, ethanol-anesthetized rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Diuresis; Ethanol; Male; Osmotic Pressure; Paraventricular Hypothalamic Nucleus; Quinidine; Rats; Rats, Wistar; Receptors, Purinergic; Stereotaxic Techniques; Theophylline; Time Factors | 1992 |
Decrease in cold tolerance of aged rats caused by the enhanced endogenous adenosine activity.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Body Temperature Regulation; Cold Temperature; Lysine; Male; Neck Muscles; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1992 |
Adenosine modulates cell growth in human epidermoid carcinoma (A431) cells.
Topics: Adenosine; Carcinoma, Squamous Cell; Cell Division; Humans; In Vitro Techniques; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured; Xanthines | 1992 |
Adenosine inhibits divalent cation influx across human neutrophil plasma membrane via surface adenosine A2 receptors.
Topics: Adenosine; Adenosine Deaminase; Adult; Calcium; Cations, Divalent; Cell Membrane; Humans; In Vitro Techniques; Ion Transport; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Purinergic; Theophylline | 1992 |
Prejunctional modulation of sensory-motor nerve mediated vasodilation of the rat mesenteric arterial bed by adenosine.
Topics: Adenosine; Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Neurons, Afferent; Rats; Rats, Wistar; Theophylline; Vasodilation; Vasomotor System | 1992 |
Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord.
Topics: Adenosine; Adenosine Monophosphate; Animals; Bicuculline; Cats; Evoked Potentials; Iontophoresis; Membrane Potentials; Naloxone; Neurons; Pain; Physical Stimulation; Purinergic Antagonists; Spinal Cord; Strychnine; Synapses; Theophylline; Vibration | 1992 |
Local antinociceptive and hyperalgesic effects in the formalin test after peripheral administration of adenosine analogues in mice.
Topics: Absorption; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Drug Interactions; Extremities; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain Measurement; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1992 |
NG-nitro-L-arginine attenuates flow debt repayment in the reactive hyperemic response of the open-chest dog coronary artery: contribution of endothelium-derived relaxing factor.
Topics: Adenosine; Animals; Arginine; Coronary Vessels; Dogs; Myocardial Ischemia; Nitric Oxide; Nitroarginine; Oxygen Consumption; Prostaglandins; Theophylline; Vasodilation | 1992 |
Relative responses to luminal and adventitial adenosine in perfused arteries.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arteries; Biological Transport; Blood Circulation; Dipyridamole; Histological Techniques; In Vitro Techniques; Male; Perfusion; Rabbits; Theophylline | 1992 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Effects of adenosine on cardiac performance and phosphate compounds in microembolised guinea pig hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Embolism; Guinea Pigs; Heart; Heart Diseases; Lactates; Magnetic Resonance Spectroscopy; Male; Myocardium; Perfusion; Phosphates; Theophylline | 1992 |
A neuroprotective effect of adenosine A1-receptor agonists on ischemia-induced decrease in 2-deoxyglucose uptake in rat hippocampal slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Ischemia; Deoxyglucose; Hippocampus; In Vitro Techniques; Male; Nervous System Diseases; Phenylisopropyladenosine; Purinergic Antagonists; Rats; Rats, Wistar; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1992 |
The role of adenosine in glycine-induced glomerular hyperfiltration in rats.
Topics: Adenosine; Adenosine Deaminase; Animals; Glomerular Filtration Rate; Glycine; Male; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Renal Circulation; Theophylline | 1992 |
Evidence that the inhibition of ATP release from sympathetic nerves by adenosine is a physiological mechanism.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Luciferases; Male; Muscle, Smooth; Neurons; Perfusion; Sympathetic Nervous System; Theophylline; Vas Deferens | 1992 |
Pharmacological characterization of a new purinergic receptor site in rabbit aorta.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Receptors, Purinergic; Theophylline; Thionucleotides; Vasodilation | 1992 |
Adenosine-induced hyperpolarization is depressed by glibenclamide in rat CA1 neurones.
Topics: 2-Chloroadenosine; Adenosine; Animals; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1992 |
Extracellular and intracellular actions of adenosine and related compounds in the reperfused rat intestine.
Topics: 2-Chloroadenosine; Adenosine; Aminoimidazole Carboxamide; Animals; Dipyridamole; Intestines; Male; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reperfusion Injury; Ribonucleosides; Theophylline | 1992 |
Interstitial adenosine with dipyridamole: effect of adenosine receptor blockade and adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dialysis; Dipyridamole; Dogs; Extracellular Space; Female; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Male; Purinergic Antagonists; Theophylline | 1992 |
Microvascular sites and mechanisms responsible for reactive hyperemia in the coronary circulation of the beating canine heart.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hyperemia; Male; Microcirculation; Microscopy; Potassium Channels; Theophylline; Vasodilation | 1992 |
Myocardial protective effects of adenosine. Infarct size reduction with pretreatment and continued receptor stimulation during ischemia.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Heart; Hemodynamics; Male; Methods; Myocardial Infarction; Myocardium; Rabbits; Receptors, Purinergic; Theophylline | 1992 |
Evidence that adenosine receptors in the dog left atrium are not of the typical A1 or A2 adenosine receptor subtypes.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Female; Heart Atria; In Vitro Techniques; Male; Myocardium; Norbornanes; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1992 |
Vasodepressor mechanisms of 2-(1-octynyl)-adenosine (YT-146), a selective adenosine A2 receptor agonist, involve the opening of glibenclamide-sensitive K+ channels.
Topics: Adenosine; Alkynes; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Injections, Intravenous; Male; Norepinephrine; Potassium Channels; Receptors, Purinergic; Theophylline | 1992 |
N-0861 selectively antagonizes adenosine A1 receptors in vivo.
Topics: Adenine; Adenosine; Animals; Dose-Response Relationship, Drug; Heart Rate; Injections, Intravenous; Male; Norbornanes; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1992 |
Endogenous adenosine contributes to hypoxic synaptic depression in hippocampus from young and aged rats.
Topics: Adenosine; Aging; Animals; Cell Hypoxia; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Nitrogen; Rats; Rats, Inbred F344; Synapses; Theophylline | 1992 |
Purinergic agonist induction of metallothionein.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cells, Cultured; Cladribine; Deoxyadenosines; Dose-Response Relationship, Drug; Immunoblotting; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; RNA, Messenger; Theophylline; Time Factors; Transcription, Genetic; Vasodilator Agents | 1992 |
Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding.
Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Injections, Intraperitoneal; Locomotion; Male; Mice; Receptors, Purinergic; Theophylline; Time Factors; Xanthines | 1992 |
Role of endothelium-derived relaxing factor in the in vivo renal vascular action of adenosine in dogs.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Dogs; Female; Hemodynamics; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenethylamines; Renal Circulation; Theophylline | 1992 |
Canine coronary vasodepressor responses to hypoxia are attenuated but not abolished by 8-phenyltheophylline.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; Hypoxia; Pressure; Solutions; Theophylline; Vasodilation | 1992 |
Ultrastructural localization of calcium in ischemic hippocampal slices: the influence of adenosine and theophylline.
Topics: Adenosine; Animals; Brain Ischemia; Calcium; Dendrites; Hippocampus; Male; Mitochondria; Organ Culture Techniques; Rats; Rats, Inbred Strains; Theophylline | 1992 |
Cerebrovascular reactivity to adenosine analogues in 0.6-0.7 gestation and near-term fetal sheep.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Cerebrovascular Circulation; Female; Fetus; Gestational Age; Pregnancy; Sheep; Theophylline; Vasodilator Agents | 1992 |
Adenosine release in morphine-induced hypotension in rats.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Blood Pressure; Dipyridamole; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Male; Morphine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Tetrabenazine; Theophylline | 1992 |
Adenosine receptor blockade reduces splanchnic hyperemia in cirrhotic rats.
Topics: Adenosine; Animals; Hemodynamics; Hyperemia; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Purinergic Antagonists; Rats; Rats, Inbred Strains; Splanchnic Circulation; Theophylline | 1992 |
Adenosine activates a vascular renin-angiotensin system in hypertensive subjects.
Topics: Adenosine; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arterioles; Blood Vessels; Captopril; Female; Forearm; Humans; Male; Middle Aged; Renin-Angiotensin System; Theophylline | 1992 |
Adenosine inhibition of the regeneration in vitro of adult frog sciatic sensory axons.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Imidodiphosphate; Animals; Axons; Cell Division; In Vitro Techniques; Nerve Regeneration; Neurons, Afferent; Rana temporaria; Schwann Cells; Sciatic Nerve; Theophylline; Thymidine | 1992 |
Chemical modification and irreversible inhibition of striatal A2a adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Amino Acid Sequence; Animals; Corpus Striatum; Diethyl Pyrocarbonate; Drug Antagonism; Hydroxylamine; Hydroxylamines; Molecular Sequence Data; Phenethylamines; Purinergic Antagonists; Rabbits; Radioligand Assay; Receptors, Purinergic; Theophylline; Xanthines | 1992 |
Role of endothelium-derived nitric oxide in myocardial reactive hyperemia.
Topics: Adenosine; Animals; Arginine; Cardiomyopathies; Coronary Circulation; Dogs; Drug Combinations; Endothelium, Vascular; Hyperemia; Nitric Oxide; omega-N-Methylarginine; Pharmaceutical Vehicles; Theophylline | 1992 |
A2 and P2 purine receptor interactions and surfactant secretion in primary cultures of type II cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); AMP Deaminase; Animals; Cells, Cultured; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Lung; Phosphatidylcholines; Pulmonary Surfactants; Receptors, Purinergic; Terbutaline; Theophylline; Thionucleotides; Xanthines | 1991 |
Elevated extracellular glucose inhibits an adenosine-(Na+,K+)-ATPase regulatory system in rabbit aortic wall.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Aorta, Thoracic; Child, Preschool; Colforsin; Diglycerides; Glucose; Glycerol; Homeostasis; Humans; In Vitro Techniques; Inositol; Male; Muscle, Smooth, Vascular; Phosphatidylinositols; Potassium; Rubidium; Sodium-Potassium-Exchanging ATPase; Theophylline | 1991 |
Sources of adenosine released during neuromuscular transmission in the rat.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Hydrolysis; Male; Neuromuscular Junction; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1991 |
Increased erythropoietin secretion in human hepatoma cells by N6-cyclohexyladenosine.
Topics: Adenosine; Anaerobiosis; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cyclic AMP; Erythropoietin; Humans; Hypoxia; Kinetics; Liver Neoplasms; Theophylline | 1991 |
Pentoxifylline does not act via adenosine receptors in the inhibition of the superoxide anion production of human polymorphonuclear leukocytes.
Topics: Adenosine; Dose-Response Relationship, Drug; Drug Combinations; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Purinergic Antagonists; Receptors, Purinergic; Superoxides; Theophylline | 1991 |
Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs.
Topics: Adenosine; Animals; Blood Pressure; Bucladesine; Colforsin; Coronary Circulation; Coronary Disease; Dogs; Platelet Activation; Platelet Aggregation; Theophylline | 1991 |
Adenosine modulation of neuroeffector transmission in guinea-pig uterine smooth muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Myometrium; Synaptic Transmission; Theophylline; Uterine Contraction | 1991 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
Intracerebroventricular morphine releases adenosine and adenosine 3',5'-cyclic monophosphate from the spinal cord via a serotonergic mechanism.
Topics: Adenosine; Animals; Cyclic AMP; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Neurotoxins; Nociceptors; Purinergic Antagonists; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Theophylline | 1991 |
Adenosine receptors involved in the inhibitory control of non-adrenergic non-cholinergic neurotransmission in guinea-pig atria belong to the A1 subtype.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Atrial Function; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Male; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Reserpine; Synaptic Transmission; Theophylline | 1991 |
Stimulation of adenosine A2 receptors induces catalepsy.
Topics: Adenosine; Animals; Azepines; Catalepsy; Male; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Synaptic Transmission; Theophylline | 1991 |
The role of intrarenal adenosine in glomerular action of atrial natriuretic factor.
Topics: Adenosine; Adenosine Deaminase; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dipyridamole; Glucagon; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Saralasin; Sodium; Theophylline | 1991 |
Extracellular guanosine increases astrocyte cAMP: inhibition by adenosine A2 antagonists.
Topics: Adenosine; Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Chick Embryo; Cyclic AMP; Guanosine; Purinergic Antagonists; Receptors, Purinergic; Second Messenger Systems; Theophylline; Xanthines | 1991 |
Nucleotide modulation of norepinephrine release from sympathetic nerves in the rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Male; Neurotransmitter Agents; Norepinephrine; Nucleotides; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline; Vas Deferens | 1991 |
Diuretic and saliuretic effects of 1,3-dipropyl-8-cyclopentylxanthine, a selective A1-adenosine receptor antagonist.
Topics: Adenosine; Animals; Blood Pressure; Diuresis; Electrolytes; Heart Rate; Infusions, Intravenous; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1991 |
Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Quinoxalines; Rats; Synapses; Synaptic Transmission; Theophylline | 1991 |
Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes.
Topics: Adenosine; Animals; Apomorphine; Benzazepines; Binding, Competitive; Cell Membrane; Corpus Striatum; Dopamine; Dopamine Agents; Kinetics; Male; Phenethylamines; Phenylisopropyladenosine; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Purinergic; Salicylamides; Theophylline | 1991 |
Mechanism for the emetic side effect of xanthine bronchodilators.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Bronchodilator Agents; Dose-Response Relationship, Drug; Ferrets; Male; Nausea; Phosphodiesterase Inhibitors; Theophylline; Vomiting; Xanthines | 1990 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
Adenosine enhances antigen-induced bronchoconstriction and histamine release in rat isolated lungs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens; Bronchi; Histamine Release; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
The role of adenosine in the hyperaemic response of the hepatic artery to portal vein occlusion (the 'buffer response').
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hepatic Artery; Hyperemia; In Vitro Techniques; Male; Portal Vein; Theophylline | 1990 |
A study of the purinoceptors mediating contraction in the rat colon.
Topics: Adenosine; Animals; Colon; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Substance P; Theophylline | 1990 |
Adenosine analogs do not inhibit the potassium-stimulated release of substance P from rat spinal cord slices.
Topics: Adenosine; Animals; In Vitro Techniques; Male; Morphine; Neurons, Afferent; Neurotransmitter Agents; Potassium; Potassium Chloride; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Theophylline | 1990 |
Differential regulation of human basophil and lung mast cell function by adenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Cyclic AMP; Dipyridamole; Histamine Release; Humans; Lung; Mast Cells; SRS-A; Theophylline | 1991 |
Evidence that adenosine is not involved in the non-adrenergic non-cholinergic relaxation in the rat duodenum.
Topics: Adenosine; Animals; Atropine; Duodenum; Electric Stimulation; Guanethidine; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth; Pressure; Rats; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1990 |
Adenosine deaminase increases release of excitatory amino acids through a mechanism independent of adenosine depletion.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Female; Hydrolysis; Phosphatidylinositols; Rats; Rats, Inbred Strains; Theophylline | 1991 |
Pharmacological blockade of Cl- pumps or Cl- channels reduces the adenosine-mediated depression of stimulus train-evoked Ca2+ fluxes in rat hippocampal slices.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Calcium; Chlorine; Evoked Potentials; Furosemide; Hippocampus; In Vitro Techniques; Ion Channels; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Effects of milrinone, sulmazole and theophylline on adenosine enhancement of antigen-induced bronchoconstriction and mediator release in rat isolated lungs.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Animals; Antigens; Bronchoconstriction; Chromatography, High Pressure Liquid; Histamine Release; Imidazoles; In Vitro Techniques; Lung; Male; Milrinone; Perfusion; Pyridones; Rats; Rats, Inbred Strains; Serotonin; Theophylline | 1991 |
Effects of theophylline on the selective increases in intratumoral blood flow induced by intracarotid infusion of adenosine and adenosine triphosphate in C6 glioma-transplanted rat brains.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Flow Velocity; Brain Neoplasms; Carotid Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Interactions; Glioma; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Theophylline | 1992 |
Extracellular ATP stimulates steroidogenesis in bovine adrenocortical fasciculata cells via P2 purinoceptors.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cattle; Cells, Cultured; Hydrocortisone; Receptors, Purinergic; Theophylline; Zona Fasciculata | 1991 |
Endogenous adenosine is an autacoid feedback inhibitor of chloride transport in the shark rectal gland.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport; Chlorides; Colforsin; Dogfish; Feedback; In Vitro Techniques; Inosine; Male; Salt Gland; Theophylline; Thioinosine | 1991 |
Antiplatelet effect of the pyrimido-pyrimidinic derivative RA-642.
Topics: Adenosine; Cardiotonic Agents; Dipyridamole; Dose-Response Relationship, Drug; Humans; Male; Mopidamol; Platelet Aggregation Inhibitors; Pyrimidines; Theophylline | 1991 |
Purinergic modulation of field stimulation responses of rat and human vas deferens smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Electric Stimulation; Guanethidine; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Quinidine; Rats; Receptors, Purinergic; Theophylline; Urinary Bladder; Vas Deferens; Vasodilator Agents | 1991 |
Effect of adenosine agonist (propentofylline) on rat hippocampal seizures induced by microdialysis with potassium: analysis using compressed EEG power spectrum array.
Topics: Adenosine; Animals; Electroencephalography; Evoked Potentials; Hippocampus; Male; Potassium; Rats; Rats, Inbred Strains; Seizures; Signal Processing, Computer-Assisted; Theophylline; Xanthines | 1991 |
8-Phenyltheophylline reverses the antinociceptive action of morphine in the periaqueductal gray.
Topics: 5,7-Dihydroxytryptamine; Adenosine; Analgesia; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Injections, Spinal; Male; Morphine; Norepinephrine; Oxidopamine; Periaqueductal Gray; Rats; Rats, Inbred Strains; Spinal Cord; Theophylline | 1991 |
Methylxanthine-induced attenuation of pecking in chickens.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Behavior, Animal; Caffeine; Chickens; Dipyridamole; Female; Male; Theophylline; Xanthines | 1991 |
Direct effects of adenylyl 5'-(beta,gamma-methylene)diphosphonate, a stable ATP analogue, on relaxant P1-purinoceptors in smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Hypoxic vasodilatation in isolated, perfused guinea-pig heart: an analysis of the underlying mechanisms.
Topics: Adenosine; Animals; Arginine; Coronary Vessels; Deoxyglucose; Glycolysis; Guinea Pigs; Hypoxia; Nitric Oxide; Nitroarginine; Perfusion; Potassium Channels; Receptors, Purinergic; Theophylline; Vascular Resistance; Vasodilation | 1991 |
Pharmacological effects of adenosine on canine penile erection.
Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Cavernous Sinus; Dipyridamole; Dogs; Drug Interactions; Electric Stimulation; Injections; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Penile Erection; Theophylline | 1991 |
Prejunctional stimulation of cholinergic nerves in rat airway smooth muscle by an adenosine analogue.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cholinergic Fibers; In Vitro Techniques; Male; Neuromuscular Junction; Phenethylamines; Rats; Rats, Inbred Strains; Theophylline; Xanthines | 1991 |
The role of adenosine in the respiratory and cardiovascular response to systemic hypoxia in the rat.
Topics: Adenosine; Animals; Blood Pressure; Female; Heart Rate; Hemodynamics; Hypoxia; Male; Rats; Rats, Inbred Strains; Respiration; Theophylline; Vasodilation | 1991 |
Adenosine and the bradycardiac response to vagus nerve stimulation in rats.
Topics: Acetylcholine; Adenosine; Animals; Blood Pressure; Electric Stimulation; Electrocardiography; Heart Rate; Rats; Rats, Inbred Strains; Reserpine; Theophylline; Vagus Nerve | 1991 |
An analysis of the mechanism of the inotropic action of some milrinone analogues in guinea-pig isolated atria.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Carbachol; Cardiotonic Agents; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Milrinone; Myocardial Contraction; Phenylisopropyladenosine; Propranolol; Pyridones; Reserpine; Theophylline | 1991 |
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines | 1991 |
Chronic theophylline treatment increases adenosine A1, but not A2, receptor binding in the rat brain: an autoradiographic study.
Topics: Adenosine; Animals; Autoradiography; Brain; Male; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Time Factors; Tissue Distribution | 1991 |
The role of adenosine in dilator responses induced in arterioles and venules of rat skeletal muscle by systemic hypoxia.
Topics: Adenosine; Animals; Arterioles; Muscles; Oxygen; Rats; Respiration; Theophylline; Time Factors; Vasodilation | 1991 |
Postsynaptic dopamine/adenosine interaction: II. Postsynaptic dopamine agonism and adenosine antagonism of methylxanthines in short-term reserpinized mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bromocriptine; Caffeine; Dopamine; Male; Mice; Motor Activity; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Sulpiride; Synapses; Theophylline; Xanthines | 1991 |
Probabilistic secretion of quanta from nerve terminals in toad (Bufo marinus) muscle modulated by adenosine.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Bufo marinus; Electrophysiology; In Vitro Techniques; Nerve Endings; Neuromuscular Junction; Purinergic Antagonists; Receptors, Purinergic; Seasons; Theophylline | 1991 |
Enhancement of endogenous excitatory amino acids by theophylline does not modify the behavioral and histological consequences of forebrain ischemia.
Topics: Adenosine; Amino Acids; Animals; Brain Ischemia; Dialysis; Male; Prosencephalon; Psychomotor Performance; Rats; Rats, Wistar; Theophylline | 1991 |
Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus.
Topics: Adenosine; Animals; Animals, Newborn; Baclofen; Cells, Cultured; Evoked Potentials; Hippocampus; Rats; Synapses; Synaptic Transmission; Theophylline | 1991 |
Adenosine derived from hydrolysis of presynaptically released ATP inhibits neuromuscular transmission in the rat.
Topics: Adenosine; Adenosine Triphosphate; Animals; Curare; In Vitro Techniques; Kinetics; Magnesium; Membrane Potentials; Motor Endplate; Rats; Synapses; Synaptic Transmission; Theophylline | 1991 |
Adenosine A1 and non-A1 receptors: intracellular analysis of the actions of adenosine agonists and antagonists in rat hippocampal neurons.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Electric Stimulation; Electrodes; Hippocampus; Male; Membrane Potentials; Neurons; Phenylisopropyladenosine; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synapses; Theophylline; Xanthines | 1991 |
86Rubidium efflux and negative inotropy induced by P1- and muscarinic-receptor agonists in guinea-pig left atria. Effects of potassium channel blockers.
Topics: 4-Aminopyridine; Adenosine; Amantadine; Animals; Carbachol; Drug Interactions; Guinea Pigs; Half-Life; Heart Atria; Male; Parasympathomimetics; Phenylisopropyladenosine; Potassium; Potassium Channels; Rubidium Radioisotopes; Theophylline | 1991 |
Adenosine A1 and A2 receptors mediate presynaptic inhibition and postsynaptic excitation in guinea pig submucosal neurons.
Topics: Acetylcholine; Adenosine; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Intestinal Mucosa; Male; Membrane Potentials; Neurons; Norepinephrine; Receptors, Nicotinic; Receptors, Purinergic; Theophylline | 1991 |
Caffeine and theophylline as adenosine receptor antagonists in humans.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Caffeine; Heart Rate; Humans; Male; Platelet Aggregation; Purinergic Antagonists; Receptors, Purinergic; Substance Withdrawal Syndrome; Theophylline | 1991 |
Selective protection by adenosine receptor agonists against DMCM-induced seizures.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Bicuculline; Carbolines; Convulsants; Female; Mice; Pentylenetetrazole; Phenylisopropyladenosine; Receptors, Purinergic; Seizures; Theophylline | 1991 |
The effects of electrical stimulation, adenosine and adenosine-5'-triphosphate (ATP) on mouse rectal muscle.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Dipyridamole; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Isotonic Solutions; Male; Mice; Muscle Contraction; Muscle, Smooth; Physostigmine; Potassium Chloride; Quinidine; Rectum; Temperature; Theophylline | 1991 |
The effect of centrally administered adenosine on fetal breathing movements.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Female; Fetus; Hydrogen-Ion Concentration; Injections, Intraventricular; Pregnancy; Pulmonary Gas Exchange; Respiration; Sheep; Theophylline | 1991 |
Activation of brain adenosine receptors evokes vasodilation in skin arterioles.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Brain; Cricetinae; Injections, Intraventricular; Male; Mesocricetus; Receptors, Purinergic; Skin; Theophylline; Vasodilation; Vasodilator Agents; Xanthines | 1991 |
Adenosine-induced dilatation of the rabbit hepatic arterial bed is mediated by A2-purinoceptors.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Female; Hepatic Artery; In Vitro Techniques; Liver Circulation; Male; Phenethylamines; Phenylisopropyladenosine; Portal Vein; Rabbits; Receptors, Purinergic; Theophylline; Vasodilation | 1991 |
Peripheral mechanisms of thermogenesis induced by ephedrine and caffeine in brown adipose tissue.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Regulation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Ephedrine; Male; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline; Xanthines | 1991 |
Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat?
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbolines; Chlordiazepoxide; Electric Stimulation; Hypothalamic Area, Lateral; Male; Midazolam; Phenylisopropyladenosine; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reinforcement, Psychology; Self Stimulation; Sensory Thresholds; Theophylline; Triazoles | 1991 |
Dilazep potentiation of adenosine-mediated superior mesenteric arterial vasodilation.
Topics: Adenosine; Animals; Cats; Dilazep; Dose-Response Relationship, Drug; Drug Synergism; Female; Male; Mesenteric Arteries; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1991 |
Striatal A2 receptor regulates apomorphine-induced turning in rats with unilateral dopamine denervation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Brain Chemistry; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Oxidopamine; Rats; Receptors, Purinergic; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical; Theophylline | 1991 |
Modified arteriolar responses to ATP after impairment of endothelium by light-dye techniques in vivo.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Arterioles; Endothelium, Vascular; Evans Blue; Fluorescein; Fluoresceins; Male; Muscles; Nitroprusside; Photochemistry; Rats; Rats, Inbred Strains; Theophylline; Vasodilation; Vasodilator Agents | 1991 |
Purinergic receptors have no major role in control of the circadian rhythm in rate of thymidine incorporation by cultured chick pineal glands.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Cells, Cultured; Chickens; Circadian Rhythm; Pineal Gland; Receptors, Purinergic; Theophylline; Thioinosine; Thymidine; Vasodilator Agents | 1991 |
Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Injections, Intraperitoneal; Locomotion; Male; Mice; Phenethylamines; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1991 |
Dilazep-induced vasodilation is mediated through adenosine receptors.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Cats; Chromatography, High Pressure Liquid; Dilazep; Female; Homeostasis; Male; Mesenteric Arteries; Receptors, Purinergic; Theophylline; Vasodilation | 1991 |
Adenosine analogs attenuate tolerance-dependence on alprazolam.
Topics: Adenosine; Alprazolam; Animals; Drug Tolerance; Male; Mice; Phenylisopropyladenosine; Substance-Related Disorders; Theophylline | 1991 |
Adenosine receptor blockade enhances isoproterenol-induced increases in cardiac interstitial adenosine.
Topics: Adenosine; Animals; Extracellular Space; In Vitro Techniques; Isoproterenol; Male; Myocardium; Perfusion; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Effects of adenosine on intrarenal oxygenation.
Topics: Adenosine; Animals; Kidney Cortex; Kidney Medulla; Male; Microelectrodes; Oxygen; Oxygen Consumption; Partial Pressure; Rats; Rats, Inbred Strains; Theophylline | 1991 |
Comparison of theophylline and enprofylline effects on human neutrophil superoxide production.
Topics: Adenosine; Adenosine Deaminase; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchodilator Agents; Chromatography, High Pressure Liquid; Drug Interactions; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Theophylline; Xanthines | 1990 |
Peripheral type benzodiazepine receptors and response to adenosine on the guinea-pig isolated trachea.
Topics: Adenosine; Animals; Benzodiazepines; Clonazepam; Diazepam; Dipyridamole; Drug Synergism; GABA-A Receptor Antagonists; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, GABA-A; Theophylline; Trachea | 1990 |
A1 adenosine receptors inhibit chloride transport in the shark rectal gland. Dissociation of inhibition and cyclic AMP.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Cyclic AMP; Dogfish; Female; In Vitro Techniques; Kinetics; Male; Perfusion; Receptors, Purinergic; Salt Gland; Somatostatin; Theophylline | 1990 |
Effects of cularine and other isoquinoline alkaloids on guinea-pig trachea and human bronchus.
Topics: Adenosine; Alkaloids; Animals; Bronchi; Calcium; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Isoquinolines; Male; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Papaverine; Potassium Chloride; Theophylline; Trachea | 1990 |
Evidence against purines being neurotransmitters of non-adrenergic, non-cholinergic nerves in rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomic Nervous System; Duodenum; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Purines; Rats; Rats, Inbred Strains; Tetrodotoxin; Theophylline | 1990 |
Sympathetic nervous system-dependent vasoconstriction in humans. Evidence for mechanistic role of endogenous purine compounds.
Topics: Adenosine; Adrenergic alpha-Antagonists; Adult; Dose-Response Relationship, Drug; Female; Forearm; Humans; Male; Papaverine; Purinergic Antagonists; Purines; Sympathetic Nervous System; Theophylline; Vasoconstriction | 1990 |
Augmentation of release of gastric somatostatin-like immunoreactivity by adenosine, adenosine triphosphate and their analogs.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Male; Peptides; Perfusion; Rats; Rats, Inbred Strains; Theophylline | 1990 |
Adenosine A2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine D2 autoreceptor activation.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Apomorphine; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine Agents; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Theophylline; Tyrosine 3-Monooxygenase | 1990 |
Chronic benzodiazepine treatment and cortical responses to adenosine and GABA.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Cerebral Cortex; Clonazepam; Diazepam; Electrodes; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; N-Methylaspartate; Serotonin; Theophylline | 1990 |
Adenosine modulation of non-adrenergic non-cholinergic neurotransmission in isolated guinea-pig atria.
Topics: Adenosine; Adenosine Deaminase; Adrenergic beta-Antagonists; Animals; Atropine; Calcitonin Gene-Related Peptide; Dipyridamole; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Male; Synaptic Transmission; Theophylline; Xanthines | 1990 |
Adenosine antagonism decreases metabolic but not functional recovery from ischemia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Heart; Hemodynamics; Male; Myocardium; Phosphates; Phosphocreatine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reperfusion Injury; Theophylline | 1991 |
The role of adenosine in the vascular adaptation of neonatal cerebral blood flow during hypotension.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Oxygen; Receptors, Purinergic; Swine; Theophylline; Vascular Resistance | 1991 |
External ATP-induced changes in [Ca2+]i and membrane currents in mammalian atrial myocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Cells, Cultured; Cobalt; Guinea Pigs; Heart; Heart Atria; Kinetics; Membrane Potentials; Nickel; Theophylline; Verapamil | 1991 |
Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms.
Topics: Adenosine; Animals; Carbachol; Deoxyadenosines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Purinergic; Theophylline; Thionucleosides; Trachea; Xanthine; Xanthines | 1991 |
Bronchial challenge with adenosine causes the release of serum neutrophil chemotactic factor in asthma.
Topics: Adenosine; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Male; Middle Aged; Neutrophils; Theophylline | 1991 |
Roles of adenosine and theophylline on the recovery of adenine nucleotides in postischemic cultured renal tubular cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Ischemia; Kidney Tubules; Rabbits; Theophylline | 1991 |
Theophylline is an antagonist of adenosine in human forearm arterioles.
Topics: Adenosine; Adult; Arterioles; Female; Humans; Male; Middle Aged; Receptors, Purinergic; Theophylline; Vasodilation | 1991 |
Evidence for the presence of P2-purinoceptors at the surface of human articular chondrocytes in monolayer culture.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Cartilage, Articular; Cells, Cultured; Humans; Indomethacin; Nucleotides; Pertussis Toxin; Prostaglandins E; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1991 |
Actions of dipyridamole on endogenous and exogenous noradrenaline in the dog mesenteric vein.
Topics: Adenosine; Animals; Catecholamines; Dipyridamole; Dogs; Electric Stimulation; Electrophysiology; Evoked Potentials; In Vitro Techniques; Male; Mesenteric Veins; Methoxyhydroxyphenylglycol; Microelectrodes; Neuromuscular Junction; Norepinephrine; Phentolamine; Theophylline | 1991 |
Chronic theophylline treatment in vivo increases high affinity adenosine A1 receptor binding and sensitivity to exogenous adenosine in the in vitro hippocampal slice.
Topics: Adenosine; Animals; Drug Resistance; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Time Factors | 1991 |
Depressant effect of adenosine in isolated human and canine atrial fibres.
Topics: Acetylcholine; Action Potentials; Adenosine; Animals; Atropine; Culture Media; Culture Techniques; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Heart Atria; Humans; Myocardial Contraction; Theophylline | 1991 |
Adenosine receptor blockade with 8-p-sulfophenyltheophylline aggravates coronary constriction.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Drug Synergism; Female; Hemodynamics; Male; Neuropeptide Y; Receptors, Purinergic; Regional Blood Flow; Theophylline; Vascular Resistance; Vasoconstriction | 1991 |
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.
Topics: Adenosine; Animals; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Purines; Rabbits; Receptors, Purinergic; Sulfonamides; Theophylline | 1991 |
Effects of CGS-15943A on the relaxations produced by adenosine analogs in human blood vessels.
Topics: Adenosine; Adult; Coronary Vessels; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Quinazolines; Saphenous Vein; Theophylline; Triazoles | 1990 |
Effect of MK-801 and its interaction with adenosinergic agents and carbamazepine against hypoxic stress-induced convulsions and death in mice.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbamazepine; Dipyridamole; Dizocilpine Maleate; Drug Interactions; Female; Male; Mice; Seizures; Stress, Physiological; Theophylline | 1990 |
ADP and glucose as possible synergistic partners in the stimulation of liver glycogen synthase activation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cytidine Diphosphate; Drug Synergism; Enzyme Activation; Glucose; Glycogen Synthase; Glycogen-Synthase-D Phosphatase; Guanosine Diphosphate; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Theophylline; Uridine Diphosphate | 1990 |
Influence of blood withdrawal and anticoagulant on clotting activity, hematologic data, and certain rheologic measurements.
Topics: Adenosine; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Coagulation; Blood Viscosity; Bloodletting; Citrates; Dipyridamole; Edetic Acid; Erythrocyte Deformability; Erythrocytes; Heparin; Humans; Male; Theophylline | 1990 |
Characterization of the human peripheral lung adenosine receptor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Aged; Binding, Competitive; Cromolyn Sodium; Female; Humans; Lung; Male; Middle Aged; Receptors, Purinergic; Theophylline | 1990 |
Fetal breathing, sleep state, and cardiovascular responses to adenosine in sheep.
Topics: Adenosine; Animals; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Female; Fetal Blood; Fetal Hypoxia; Fetus; Heart Rate, Fetal; Oxygen; Pregnancy; Respiration; Sheep; Sleep, REM; Theophylline | 1990 |
Effects of long-term theophylline treatment on adenosine A1-receptors in rat brain: autoradiographic evidence for increased receptor number and altered coupling to G-proteins.
Topics: Adenosine; Animals; Autoradiography; Brain; GTP-Binding Proteins; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
Adenosine mediates calcium-induced antinociception and potentiation of noradrenergic antinociception in the spinal cord.
Topics: 5,7-Dihydroxytryptamine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Drug Synergism; Hot Temperature; Hydroxydopamines; Male; Methysergide; Norepinephrine; Oxidopamine; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Serotonin; Spinal Cord; Theophylline | 1990 |
NMDA-receptor-independent effects of low magnesium: involvement of adenosine.
Topics: Action Potentials; Adenosine; Animals; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Theophylline | 1990 |
Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain Chemistry; Caffeine; Carbamazepine; Clonidine; Cyclic AMP; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenylisopropyladenosine; Purines; Receptors, Adrenergic; Sulfonamides; Theophylline; Xanthines | 1990 |
Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cell Line; Chlorides; Cyclic AMP; Cyclic GMP; Cytosol; Electrolytes; Epithelium; Histamine; Humans; Inflammation; Kinetics; Phenylisopropyladenosine; Phosphorylation; Protein Kinases; Theophylline | 1990 |
Adenosine receptor antagonism attenuates angiotensin II effects on adrenergic neurotransmission in the rabbit isolated vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Adrenergic; Receptors, Purinergic; Synaptic Transmission; Theophylline; Vas Deferens | 1990 |
Pertussis toxin pretreatment reveals differential effects of adenosine analogs on IgE-dependent histamine and peptidoleukotriene release from RBL-2H3 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cell Line; Histamine; Immunoglobulin E; Kinetics; Leukotrienes; Mast Cells; Peptides; Pertussis Toxin; Theophylline; Virulence Factors, Bordetella | 1990 |
The antiinflammatory effects of adenosine receptor agonists on the carrageenan-induced pleural inflammatory response in rats.
Topics: Adenosine; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Captopril; Carrageenan; Clonidine; Leukocyte Count; Minoxidil; Neutrophils; Pleurisy; Rats; Receptors, Purinergic; Superoxides; Theophylline | 1990 |
Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antigens, Differentiation; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Humans; In Vitro Techniques; Neutrophils; Pertussis Toxin; Phagocytosis; Phenylisopropyladenosine; Receptors, Fc; Receptors, IgG; Receptors, Purinergic; Superoxides; Theophylline; Virulence Factors, Bordetella | 1990 |
Regional difference in responsiveness of adenosine-sensitive cyclic AMP-generating systems in chronic epileptic cerebral cortex of the rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Epilepsy; In Vitro Techniques; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Mechanism of adenosine-induced inhibition of calcium current in guinea pig ventricular cells.
Topics: Adenosine; Animals; Calcium; Calcium Channels; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Models, Cardiovascular; Myocardium; Theophylline | 1990 |
Multiple mechanisms of xanthine actions on airway reactivity.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Administration, Inhalation; Aerosols; Animals; Blood Pressure; Bronchi; Bronchoconstriction; Bronchodilator Agents; Carbachol; Guinea Pigs; Heart Rate; Histamine; Lung; Male; Ovalbumin; Platelet Activating Factor; SRS-A; Theophylline; Xanthines | 1990 |
Interaction between angiotensin II and adenosine in mediating the vasoconstrictor response to intrarenal hypertonic saline infusions in the dog.
Topics: Adenosine; Angiotensin II; Animals; Captopril; Dogs; Kidney; Renal Circulation; Saline Solution, Hypertonic; Theophylline; Vasoconstriction | 1990 |
Endogenous adenosine enhances vagal negative chronotropic effect during hypoxia in the anaesthetised rabbit.
Topics: Adenosine; Anesthesia; Animals; Depression, Chemical; Female; Heart Rate; Hypoxia; Male; Rabbits; Theophylline; Vagus Nerve | 1990 |
The role of adenosine in exercise hyperaemia of the gracilis muscle in anaesthetized cats.
Topics: Adenosine; Animals; Cats; Hyperemia; Leg; Muscle Contraction; Muscles; Physical Exertion; Regional Blood Flow; Theophylline | 1990 |
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline.
Topics: Adenosine; Aminophylline; Amygdala; Animals; Brain; Carbolines; Diazepam; Flumazenil; Kindling, Neurologic; Male; Picrotoxin; Pyrazoles; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Purinergic; Rolipram; Seizures; Theophylline; Xanthines | 1990 |
Hypoxia-induced vasodilation of the feline superior mesenteric artery is not adenosine mediated.
Topics: Adenosine; Animals; Cats; Hypoxia; Isoproterenol; Mesenteric Arteries; Oxygen; Partial Pressure; Receptors, Purinergic; Theophylline; Vasodilation | 1990 |
Effects of adenosine and its analogues on isolated internal carotid arteries from newborn and adult pigs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Carotid Arteries; Dose-Response Relationship, Drug; In Vitro Techniques; Phenylisopropyladenosine; Swine; Theophylline | 1990 |
Caffeine and theophylline attenuate adenosine-induced vasodilation in humans.
Topics: Adenosine; Adolescent; Adult; Bronchodilator Agents; Caffeine; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Regional Blood Flow; Theophylline; Vasodilation; Xanthines | 1990 |
Modulatory action of adenosine on gastric function and ethanol-induced mucosal damage in rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Ethanol; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Rats; Regional Blood Flow; Stomach Diseases; Theophylline | 1990 |
A role for adenosine calcium and ischemia in radiocontrast-induced intrarenal vasoconstriction.
Topics: Acute Kidney Injury; Adenosine; Animals; Biological Transport, Active; Calcium; Contrast Media; Diatrizoate Meglumine; Diltiazem; Dogs; Female; Ischemia; Male; Renal Circulation; Sodium; Theophylline; Vasoconstriction; Verapamil | 1990 |
Adenosine decreases the minimum alveolar concentration of halothane in dogs.
Topics: Adenosine; Aminophylline; Anesthesia; Animals; Dipyridamole; Dogs; Halothane; Pulmonary Alveoli; Receptors, Purinergic; Theophylline | 1990 |
Cerebral ischemia in gerbils: postischemic administration of cyclohexyl adenosine and 8-sulfophenyl-theophylline.
Topics: Adenosine; Animals; Blood Pressure; Brain Ischemia; Drug Interactions; Female; Gerbillinae; Theophylline | 1990 |
2-Chloroadenosine decreases long-term potentiation in the hippocampal CA1 area of the rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Electric Stimulation; Electrodes, Implanted; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Synapses; Theophylline | 1990 |
Role of adenosine in regulation of regional cerebral blood flow in sensory cortex.
Topics: Adenosine; Administration, Topical; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Electric Stimulation; Evoked Potentials, Somatosensory; Inosine; Male; Pia Mater; Rats; Rats, Inbred Strains; Sciatic Nerve; Somatosensory Cortex; Theophylline; Vasodilation | 1990 |
Central adenosinergic system involvement in ethanol-induced motor incoordination in mice.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Brain; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenylisopropyladenosine; Psychomotor Performance; Receptors, Purinergic; Theophylline; Time Factors; Tissue Distribution; Tritium; Xanthines | 1990 |
Adenosine involvement in postictal events in amygdala-kindled rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amygdala; Animals; Anticonvulsants; Caffeine; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Kindling, Neurologic; Male; Rats; Seizures; Theophylline; Time Factors | 1990 |
Determination of the effectiveness of DPSPS as an adenosine receptor antagonist in vivo.
Topics: Adenosine; Animals; Cats; Female; Hepatic Artery; Isoproterenol; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Neural Conduction; Purinergic Antagonists; Theophylline; Xanthines | 1990 |
Adenosine is not essential for exercise hyperaemia in the hindlimb in conscious dogs.
Topics: Adenosine; Aminophylline; Animals; Blood Pressure; Dogs; Heart Rate; Hindlimb; Physical Exertion; Receptors, Purinergic; Regional Blood Flow; Theophylline; Vascular Resistance | 1990 |
Relation of adenosine to medullary injury in the perfused rat kidney.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport; Kidney Diseases; Kidney Medulla; Male; Perfusion; Rats; Rats, Inbred Strains; Theophylline; Thioinosine | 1990 |
Theophylline inhibits isoproterenol-induced coronary dilatation in the isolated perfused rat heart.
Topics: Adenosine; Animals; Coronary Circulation; Hemodynamics; Hyperemia; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1990 |
Release of endogenous adenosine does not mediate electrophysiological responses to morphine in the hippocampus in vitro.
Topics: Adenosine; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Morphine; Rats; Rats, Inbred Strains; Synapses; Theophylline; Time Factors | 1990 |
Characterization of the locomotor depression produced by an A2-selective adenosine agonist.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Male; Mice; Molecular Structure; Motor Activity; Phenethylamines; Receptors, Purinergic; Theophylline | 1990 |
Effects of adenosine on adrenergically induced renal vasoconstriction in dogs.
Topics: Adenosine; Anesthesia; Animals; Dipyridamole; Dogs; Electric Stimulation; Female; Kidney; Male; Norepinephrine; Renal Circulation; Sympathetic Nervous System; Theophylline; Vasoconstriction | 1990 |
Enhancement of maximal thermogenesis by reducing endogenous adenosine activity in the rat.
Topics: Adenosine; Adenosine Deaminase; Aminophylline; Animals; Body Temperature Regulation; Male; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
The selective adenosine A2 receptor agonist, CGS 21680, is a potent depressant of cerebral cortical neuronal activity.
Topics: Adenosine; Animals; Cerebral Cortex; Evoked Potentials; Male; Neural Inhibition; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Adenosine antagonists alter the synaptic response to in vitro ischemia in the rat hippocampus.
Topics: Action Potentials; Adenosine; Animals; Cell Hypoxia; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Rats; Rats, Inbred Strains; Theophylline | 1990 |
Theophylline reduces cerebral hyperaemia and enhances brain damage induced by seizures.
Topics: Adenosine; Animals; Cerebrovascular Circulation; Kainic Acid; Male; Rats; Rats, Inbred Strains; Seizures; Theophylline | 1990 |
Anoxia reveals a vulnerable period in the development of long-term potentiation.
Topics: Action Potentials; Adaptation, Physiological; Adenosine; Animals; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Rats; Theophylline | 1990 |
Pharmacological evidence for the modulation of monoamine release by adenosine in the invertebrate nervous system.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biogenic Amines; Bivalvia; Dopamine Antagonists; Dose-Response Relationship, Drug; Nervous System; Potassium; Serotonin Antagonists; Theophylline | 1990 |
Adenosine depresses spontaneous transmitter release from frog motor nerve terminals by acting at an A1-like receptor.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Membrane Potentials; Motor Neurons; Phenylisopropyladenosine; Purinergic Antagonists; Rana pipiens; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
Influence of adenosine on cerebral blood flow during hypoxic hypoxia in the newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Arteries; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Hypoxia; Injections, Intraventricular; Inosine; Oxygen; Swine; Theophylline; Vascular Resistance | 1990 |
[Effect of shakuyaku-extract on electrical stimulation induced contraction of guinea pig ileum].
Topics: Adenosine; Animals; Depression, Chemical; Drugs, Chinese Herbal; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phentolamine; Theophylline | 1990 |
Temperature-sensitive adenosine-mediated vasoconstriction in the skin microcirculation.
Topics: Adenosine; Administration, Topical; Animals; Cricetinae; Male; Mesocricetus; Microcirculation; Receptors, Purinergic; Skin; Skin Temperature; Theophylline; Vasoconstriction | 1990 |
The role of adenosine in HgCl2-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Adenosine; Animals; Dose-Response Relationship, Drug; Hemodynamics; In Vitro Techniques; Kidney; Mercuric Chloride; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Theophylline | 1990 |
Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus.
Topics: Adenosine; Animals; Gerbillinae; Ischemic Attack, Transient; Male; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Xanthines | 1990 |
Adenosine modulation of resting vascular tone in rabbit skeletal muscle.
Topics: Adenosine; Animals; Arteries; Arterioles; Dose-Response Relationship, Drug; Microcirculation; Muscles; Rabbits; Theophylline; Vasoconstriction; Vasomotor System; Xanthines | 1990 |
Inositol phospholipid hydrolysis in human brain; adenosine inhibition of the response to histamine.
Topics: 2-Chloroadenosine; Adenosine; Adult; Aged; Brain; Carbachol; Female; Histamine; Humans; In Vitro Techniques; Inositol Phosphates; Male; Middle Aged; Norepinephrine; Potassium Chloride; Serotonin; Theophylline | 1990 |
Time-dependent effects of theophylline on myocardial reactive hyperaemias in the anaesthetized dog.
Topics: Adenosine; Anesthesia; Animals; Coronary Circulation; Dogs; Female; Hyperemia; Male; Models, Biological; Oxygen Consumption; Theophylline; Time Factors | 1990 |
The effect of adenosine on the fluorescence responses of chlorotetracycline-loaded human polymorphonuclear leukocytes.
Topics: Adenosine; Adenosine Deaminase; Calcium; Cell Membrane; Chlortetracycline; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Spectrometry, Fluorescence; Theophylline | 1990 |
Role of purinergic system in tracheobronchial reactivity of healthy and bronchopathic subjects.
Topics: Adenosine; Adolescent; Adult; Aged; Albuterol; Aminophylline; Asthma; Bronchi; Bronchitis; Bronchodilator Agents; Child; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Metaproterenol; Middle Aged; Receptors, Purinergic; Theophylline; Trachea | 1990 |
Action of N6(amido-3-propyl) adenosine hydrochloride (Agr 529) on plasma corticosterone levels in rats.
Topics: Adenosine; Animals; Corticosterone; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Evidence that A2 purinoceptors are involved in endothelium-dependent relaxation of the rat thoracic aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Theophylline stimulates fetal breathing movements during hypoxia.
Topics: Adenosine; Animals; Female; Fetal Hypoxia; Fetus; Pregnancy; Respiratory Mechanics; Sheep; Theophylline | 1990 |
Inosine transiently decreases coronary flow but potentiates vasodilation by adenosine.
Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Drug Synergism; In Vitro Techniques; Inosine; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Theophylline; Time Factors; Vasodilation | 1990 |
Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dilazep; Kainic Acid; Limbic System; Male; Rats; Rats, Inbred Strains; Seizures; Theophylline | 1990 |
Theophylline down-regulates adenosine receptor function.
Topics: Adenosine; Animals; Aspartic Acid; Isoproterenol; Male; Mice; N-Methylaspartate; Receptors, Purinergic; Serotonin; Theophylline | 1990 |
2-Chloro-[3H]-adenosine binding in isolated rat kidney membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; In Vitro Techniques; Kidney; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Characteristics of adenosine binding sites in atrial sarcolemmal membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; Cattle; Endopeptidases; Heart Atria; Myocardium; Sarcolemma; Subcellular Fractions; Theophylline; Time Factors | 1985 |
Adenosine receptors on canine parietal cells modulate gastric acid secretion to histamine.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dogs; Dose-Response Relationship, Drug; Female; Gastric Acid; Histamine; In Vitro Techniques; Male; Parietal Cells, Gastric; Phenylisopropyladenosine; Prostaglandins; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Effects of bronchoconstrictors and bronchodilators on a novel human small airway preparation.
Topics: Adenosine; Adenosine Triphosphate; Bronchi; Bronchodilator Agents; Carbachol; Histamine; Humans; In Vitro Techniques; Lung; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandin D2; Prostaglandins D; Substance P; Terbutaline; Theophylline; Xanthines | 1985 |
Adenosine potentiates immunological histamine release from rat mast cells by a novel cyclic AMP-independent cell-surface action.
Topics: Adenosine; Animals; Cyclic AMP; Histamine Release; In Vitro Techniques; Male; Mast Cells; Rats; Rats, Inbred Strains; Theophylline; Time Factors | 1985 |
Adenosine-sensitive adenylate cyclase in rat anterior pituitary.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cations, Divalent; Deoxyadenosines; Female; Guanine Nucleotides; In Vitro Techniques; Phenylisopropyladenosine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Theophylline | 1985 |
Modulation of the behavioral effects of chlordiazepoxide by methylxanthines and analogs of adenosine in squirrel monkeys.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Chlordiazepoxide; Conditioning, Psychological; Male; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Saimiri; Theobromine; Theophylline; Xanthines | 1985 |
Apparent enhancement of cholinergic transmission in rabbit bronchi via adenosine A2 receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Phenylisopropyladenosine; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Substance P; Synaptic Transmission; Theophylline; Xanthines | 1986 |
Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenine Nucleotides; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Serotonin; Tachyphylaxis; Theophylline; Time Factors; Tubercidin | 1986 |
A1 and A2 adenosine receptors regulate adenylate cyclase in cultured human lung fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Line; Cyclic AMP; Fibroblasts; Humans; Lung; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1986 |
The effect of adenosine and its analogues on cyclic AMP changes and histamine secretion from rat peritoneal mast cells stimulated by various ligands.
Topics: Adenosine; Animals; Calcimycin; Concanavalin A; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Histamine Release; Immunoglobulin E; In Vitro Techniques; Ligands; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline | 1986 |
Regulation of bovine sperm motility and cyclic adenosine 3',5'-monophosphate by adenosine and its analogues.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Bicarbonates; Cattle; Cyclic AMP; Dibucaine; Male; Sperm Motility; Spermatozoa; Structure-Activity Relationship; Theophylline | 1986 |
Adenosine induced immunosuppression: the role of the adenosine receptor--adenylate cyclase interaction in the alteration of T-lymphocyte surface phenotype and immunoregulatory function.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Adult; Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Humans; Immune Tolerance; Isoproterenol; Kinetics; Receptors, Cell Surface; Receptors, Purinergic; T-Lymphocytes; Theophylline | 1986 |
Mucosal adenosine stimulates chloride secretion in canine tracheal epithelium.
Topics: 2-Chloroadenosine; Adenosine; Animals; Chlorides; Cyclic AMP; Dogs; Ion Channels; Mucous Membrane; Receptors, Cell Surface; Receptors, Purinergic; Sodium; Stimulation, Chemical; Theophylline; Trachea | 1986 |
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Action Potentials; Adenosine; Adenylyl Cyclases; Animals; Baclofen; Calcium; Cells, Cultured; Depression, Chemical; Ganglia, Spinal; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Analgesia; Animals; Caffeine; Hyperalgesia; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Nociceptors; Spinal Cord; Theophylline; Xanthines | 1986 |
Characteristics of high affinity and low affinity adenosine binding sites in human cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Cerebral Cortex; Humans; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1986 |
Therapeutic concentrations of theophylline and enprofylline potentiate catecholamine effects and inhibit leukocyte activation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adult; Bucladesine; Calcimycin; Calcium; Catecholamines; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoproterenol; Middle Aged; Neutrophils; Prostaglandins E; Theophylline; Xanthines | 1986 |
Effect of chronically administered methylxanthines on ethanol-induced motor incoordination in mice.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Brain; Caffeine; Drug Synergism; Ethanol; Kinetics; Male; Mice; Motor Activity; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
ATP release from affinity-purified rat cholinergic nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Cholinergic Fibers; Chromatography, High Pressure Liquid; Potassium Chloride; Rats; Sheep; Theophylline; Veratridine | 1987 |
Discriminative stimulus properties of caffeine in the rat: noradrenergic mediation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adrenergic alpha-Antagonists; Animals; Apomorphine; Avoidance Learning; Caffeine; Clonidine; Diazepam; Discrimination Learning; Male; Norepinephrine; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1986 |
Adenosine receptors in post-mortem human cerebral cortex and the effect of carbamazepine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Binding, Competitive; Carbamazepine; Cerebral Cortex; Humans; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Postmortem Changes; Receptors, Purinergic; Software; Theophylline | 1986 |
Methylxanthine bronchodilators potentiate multiple human neutrophil functions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Aminophylline; Bronchodilator Agents; Cell Aggregation; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Receptors, Purinergic; Superoxides; Theophylline; Xanthines | 1987 |
Effect of temperature on atrial and ventricular adenosine A1 receptors of the guinea pig.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenylyl Cyclase Inhibitors; Animals; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Receptors, Purinergic; Temperature; Theophylline | 1986 |
Spinal antinociceptive effects of adenosine compounds in mice.
Topics: Adenine Nucleotides; Adenosine; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Substance P; Theophylline | 1987 |
The relation between effects of adenosine, theophylline and enprofylline on the contractility of sensitized guinea-pig lung strips.
Topics: Adenosine; Animals; Antigens; Bronchodilator Agents; Dipyridamole; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Respiratory Muscles; SRS-A; Theophylline; Xanthines | 1987 |
Dual actions of adenosine on rat peritoneal mast cells.
Topics: Adenosine; Adenylyl Cyclases; Animals; Calcimycin; Cell Membrane; Cyclic AMP; Histamine Release; In Vitro Techniques; Male; Mast Cells; Peritoneal Cavity; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1987 |
Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Dipyridamole; Endothelium; Ethanol; Isoproterenol; Male; Microcirculation; Rabbits; Theophylline; Trifluoperazine; Xanthines | 1987 |
Adenosine inhibits immunoglobulin E-dependent histamine secretion from human basophil leukocytes by two independent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunoglobulin E; Methylation; Phospholipids; S-Adenosylmethionine; Theophylline; Tubercidin | 1987 |
Measurement of antagonist affinity for purine receptors of drugs producing concomitant phosphodiesterase blockade: the use of pharmacologic resultant analysis.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Regression Analysis; Theophylline; Vas Deferens | 1987 |
Theophylline's inhibition of antigen-induced contraction of human parenchymal strips is independent of adenosine antagonism.
Topics: Adenosine; Airway Resistance; Antigens; Bronchodilator Agents; Histamine Release; Humans; In Vitro Techniques; Lung; Respiratory Hypersensitivity; Theophylline; Xanthines | 1987 |
Independent control of channel closure and block of open channels by methylxanthines at acetylcholine receptors in frog.
Topics: Action Potentials; Adenosine; Animals; Computer Simulation; In Vitro Techniques; Ion Channels; Kinetics; Motor Endplate; Rana pipiens; Rana temporaria; Receptors, Cholinergic; Theophylline; Xanthines | 1987 |
Adenosine inhibits the positive inotropic effect of 3-isobutyl-1-methylxanthine in papillary muscles without effect on cyclic AMP or cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Adenosine; Animals; Calcium; Cyclic AMP; Cyclic GMP; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylisopropyladenosine; Theophylline | 1988 |
On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Diaphragm; Evoked Potentials; Female; In Vitro Techniques; Male; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Rats; Rats, Inbred Strains; Receptors, Purinergic; Temperature; Theophylline | 1988 |
Effect of theophylline on renal vasoactivity of acetate and adenosine.
Topics: Acetates; Adenosine; Animals; Blood Pressure; Dogs; In Vitro Techniques; Renal Circulation; Theophylline | 1988 |
[Receptors for polysaccharides of group A streptococci on human thymic lymphocytes. Stimulation of their expression by action of adenosine, theophylline and supernatant of thymocytes].
Topics: Adenosine; Adolescent; Cells, Cultured; Child; Epitopes; Fluorescent Antibody Technique; Humans; Polysaccharides, Bacterial; Receptors, Immunologic; Streptococcus pyogenes; T-Lymphocytes; Theophylline | 1988 |
Inhibition by adenosine of histamine and leukotriene release from human basophils.
Topics: 2-Chloroadenosine; Adenosine; Basophils; Coformycin; Histamine Release; Humans; In Vitro Techniques; Pentostatin; SRS-A; Structure-Activity Relationship; Theophylline | 1989 |
The ability of denbufylline to inhibit cyclic nucleotide phosphodiesterase and its affinity for adenosine receptors and the adenosine re-uptake site.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; In Vitro Techniques; Kinetics; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Thioinosine; Xanthines | 1989 |
Effects of N6,2'-O-dibutyryladenosine 3',5'-cyclic monophosphate, adenosine, and of oxotremorine and 3-isobutyl-1-methylxanthine on the electrically evoked [3H]acetylcholine secretion in the guinea-pig ileum myenteric plexus.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Bucladesine; Electric Stimulation; Guinea Pigs; Ileum; Myenteric Plexus; Oxotremorine; Physostigmine; Receptors, Muscarinic; Theophylline | 1989 |
Inhibition of porcine adipose tissue lipogenesis by beta-adrenergic agonists.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Adrenergic beta-Agonists; Animals; Caffeine; Drug Interactions; Epinephrine; Isoproterenol; Lipids; Male; Propranolol; Swine; Theophylline | 1989 |
Co-purification of A1 adenosine receptors and guanine nucleotide-binding proteins from bovine brain.
Topics: Adenosine; Affinity Labels; Animals; Brain Chemistry; Cattle; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Molecular Weight; Receptors, Purinergic; Theophylline; Thionucleotides; Xanthines | 1989 |
Adenosine receptor-mediated relaxation in coronary artery: evidence for a guanyl nucleotide-binding regulatory protein involvement.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cholera Toxin; Colforsin; Coronary Vessels; Ethylmaleimide; GTP-Binding Proteins; In Vitro Techniques; Receptors, Purinergic; Theophylline; Vasodilation | 1989 |
Metabolic effects of acetate on the heart.
Topics: Acetates; Acetic Acid; Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Coronary Circulation; Dipyridamole; Glucose; Heart; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1989 |
In vivo and in vitro evidence of an adenosine-mediated mechanism of calcium entry blocker activities.
Topics: Adenosine; Arterial Occlusive Diseases; Calcium Channel Blockers; Dipyridamole; Female; Flunarizine; Humans; Intermittent Claudication; Leg; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neutrophils; Regional Blood Flow; Superoxides; Theophylline | 1989 |
Adenosine enhancement of adrenergic neuroeffector transmission in guinea-pig pulmonary artery.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Norepinephrine; Pulmonary Artery; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Vasoconstriction; Vasodilator Agents | 1989 |
Lipolytic activity of porcine adipose tissue after preincubation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adipose Tissue; Animals; Bucladesine; Female; Insulin; Isoproterenol; Lipolysis; Male; Propranolol; Swine; Theophylline | 1989 |
The effects of purine nucleotides on transmission in vesical parasympathetic ganglia of the cat.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cats; Dihydroergotamine; Female; Ganglia, Parasympathetic; Male; Norepinephrine; Propranolol; Purine Nucleotides; Synaptic Transmission; Theophylline; Urinary Bladder | 1989 |
Diazepam enhances the inhibitory action of adenosine on transmission at the frog neuromuscular junction.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diazepam; Dipyridamole; Drug Synergism; In Vitro Techniques; Membrane Potentials; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Rana ridibunda; Synaptic Transmission; Theophylline | 1989 |
Effect of theophylline and adenosine on eosinophil function.
Topics: Adenosine; Adenosine Deaminase; Animals; Anions; Eosinophilia; Eosinophils; Guinea Pigs; Humans; In Vitro Techniques; Male; Opsonin Proteins; Receptors, Purinergic; Stimulation, Chemical; Superoxides; Theophylline; Zymosan | 1989 |
Enhanced sensitivity of heart cells to adenosine and up-regulation of receptor number after treatment of guinea pigs with theophylline.
Topics: Acetylcholine; Adenosine; Animals; Cell Membrane; Cyclic AMP; Guinea Pigs; Isoproterenol; Myocardium; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline; Up-Regulation | 1989 |
Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective adenosine receptor antagonist, on force of contraction in guinea-pig atrial and ventricular cardiac preparations.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoenzymes; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Phosphoric Diester Hydrolases; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Beneficial effects of alpha 2-adrenoceptor activity on ischemic myocardium during coronary hypoperfusion in dogs.
Topics: Acidosis; Adenosine; Animals; Blood Pressure; Clonidine; Coronary Circulation; Coronary Disease; Cyclic AMP; Dogs; Hemodynamics; Lactates; Myocardial Contraction; Myocardium; Norepinephrine; Oxygen Consumption; Propranolol; Receptors, Adrenergic, alpha; Theophylline; Vasodilation; Yohimbine | 1989 |
Coordinate regulation of adenosine A1 and A2 receptors.
Topics: Adenosine; Alprostadil; Animals; Binding Sites; Cell Line; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Ethanol; Mice; Receptors, Purinergic; Theophylline; Time Factors | 1989 |
A1-adenosine receptor-mediated inhibition of adipocyte adenylate cyclase and lipolysis in Zucker rats.
Topics: Adenosine; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Cells, Cultured; Cyclic AMP; Female; Glycerol; Lipolysis; Obesity; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Zucker; Receptors, Purinergic; Theophylline; Virulence Factors, Bordetella | 1989 |
Propentofylline and a hydroxy metabolite augment A2-receptor mediated cyclic AMP accumulation and attenuate A1-receptor mediated inhibition of acetylcholine release in the rat hippocampus.
Topics: Acetylcholine; Adenosine; Animals; Cyclic AMP; Dipyridamole; Hippocampus; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Inositol phospholipid hydrolysis and potentiation of cyclic AMP formation by noradrenaline in rat cerebral cortex slices are not mediated by the same alpha-adrenoceptor subtypes.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Hydrolysis; Inositol Phosphates; Isoproterenol; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sugar Phosphates; Theophylline; Yohimbine | 1989 |
Presynaptic modulation of sympathetic nerve transmission--an element in vasomotor control.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Hydroxydopamines; Muscles; Oxidopamine; Phentolamine; Phenylisopropyladenosine; Rana temporaria; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin; Theophylline; Vasomotor System; Video Recording; Xanthines | 1989 |
Angina pectoris, adenosine, and theophylline.
Topics: Adenosine; Angina Pectoris; Humans; Infusions, Intra-Arterial; Theophylline | 1989 |
Inhibitory effect of adenine nucleotides and anti-allergic drugs on phosphorylation of phosphatidylinositol in rat mast cell granules.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cromolyn Sodium; Cytoplasmic Granules; Histamine H1 Antagonists; Ketotifen; Mast Cells; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Phthalazines; Rats; Theophylline | 1989 |
Effects of adenosine antagonism and beta-blockade during low-flow ischaemia in rat heart.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood Pressure; Catecholamines; Coronary Disease; Heart Rate; Male; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Evidence for an adenosine A2/Ra receptor on human basophils.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Basophils; Biological Transport; Calcimycin; Histamine Release; Humans; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Thioinosine | 1985 |
Methyl xanthines enhance taste: evidence for modulation of taste by adenosine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adult; Animals; Caffeine; Female; Humans; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Taste; Theobromine; Theophylline; Xanthines | 1985 |
Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Ibuprofen; Lung; Prostaglandin Endoperoxides; Pulmonary Circulation; Receptors, Purinergic; Sheep; Theophylline; Thromboxane A2; Thromboxane B2; Time Factors; Vasoconstriction | 1989 |
Effect of ethanol on splanchnic hemodynamics in awake and unrestrained rats with portal hypertension.
Topics: Adenosine; Animals; Colon; Constriction; Ethanol; Hypertension, Portal; Ileum; Male; Portal Vein; Rats; Rats, Inbred Strains; Splanchnic Circulation; Theophylline; Veins; Venous Pressure | 1989 |
Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts.
Topics: Adenosine; Anaphylaxis; Animals; Antigens; Atrioventricular Node; Coronary Circulation; Guinea Pigs; Heart; Hemodynamics; Histamine; Hypoxia; In Vitro Techniques; Inosine; Male; Myocardium; Theophylline; Thromboxanes | 1989 |
Evidence for adenosine receptor-mediated hyperpolarization in coronary smooth muscle.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Coronary Vessels; Electrophysiology; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Chloride; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1989 |
Maintenance of hepatic arterial blood flow during hemorrhage is mediated by adenosine.
Topics: Adenosine; Animals; Body Temperature; Cats; Female; Hemorrhage; Liver Circulation; Male; Receptors, Purinergic; Splanchnic Circulation; Theophylline | 1989 |
The effect of adenosine and adenosine analogues on methylxanthine-induced hypercalciuria in the rat.
Topics: Adenosine; Animals; Body Weight; Caffeine; Calcium; Diet; Diuresis; Male; Rats; Rats, Inbred Strains; Theobromine; Theophylline; Xanthines | 1989 |
Subsensitivity of presynaptic adenosine A1-receptors in caudal arteries of spontaneously hypertensive rats.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Electric Stimulation; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Purinergic; Species Specificity; Theophylline; Vasoconstriction | 1989 |
The role of adenosine and prostacyclin in coronary flow regulation in healthy man.
Topics: Adenosine; Adult; Coronary Circulation; Epoprostenol; Female; Humans; Ibuprofen; Male; Oxygen Consumption; Physical Exertion; Receptors, Purinergic; Theophylline | 1989 |
Inhibition of renal vasoconstriction induced by intrarenal hypertonic saline by the nonxanthine adenosine antagonist CGS 15943A.
Topics: Adenosine; Animals; Dogs; Quinazolines; Receptors, Purinergic; Renal Circulation; Saline Solution, Hypertonic; Sodium Chloride; Theophylline; Triazoles; Vasoconstriction | 1989 |
Penetration of theophylline and adenosine into excised human skin from binary and ternary vehicles: effect of a nonionic surfactant.
Topics: Adenosine; Humans; In Vitro Techniques; Paraffin; Pharmaceutical Vehicles; Polidocanol; Polyethylene Glycols; Skin Absorption; Surface-Active Agents; Theophylline | 1989 |
Preservation of coronary flow reserve in stunned myocardium.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Female; Hyperemia; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Reference Values; Theophylline | 1989 |
Evaluation of adenosine agonists as potential analgesics.
Topics: Adenosine; Analgesics; Animals; Ataxia; Hypnotics and Sedatives; Male; Mice; Postural Balance; Psychomotor Performance; Theophylline | 1989 |
NECA-induced hypomotility in mice: evidence for a predominantly central site of action.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Central Nervous System; Male; Mice; Motor Activity; Receptors, Purinergic; Theophylline | 1989 |
Release of endogenous glutamate from rat cerebellar synaptosomes: interactions with adenosine and ethanol.
Topics: Adenosine; Animals; Cerebellum; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Ethanol; Glutamates; Male; Rats; Rats, Inbred Strains; Synaptosomes; Theophylline; Time Factors | 1989 |
The effect of local infusion of adenosine and adenosine analogues on local cerebral blood flow.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebrovascular Circulation; Dialysis; Injections, Intraventricular; Perfusion; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Adenosine-induced hyperemia attenuates myocardial ischemia in coronary microembolization in dogs.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Embolism; Microspheres; Myocardium; Prazosin; Theophylline; Vasodilation | 1989 |
Analysis of the direct and indirect effects of adenosine on atrial and ventricular cardiac muscle.
Topics: Adenosine; Animals; Atrial Function; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardial Contraction; Papillary Muscles; Theophylline; Tyramine; Ventricular Function | 1989 |
Adenosine antagonists delay hypoxia-induced depression of neuronal activity in hippocampal brain slice.
Topics: Action Potentials; Adenosine; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Neural Inhibition; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Central actions of adenosine on pituitary secretion of prolactin, luteinizing hormone and thyrotropin.
Topics: Adenosine; Animals; Female; Luteinizing Hormone; Male; Pituitary Gland; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Thyrotropin | 1989 |
Adenosine receptors linked to adenylate cyclase activity in human neuroblastoma cells: modulation during cell differentiation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Calcium; Cell Differentiation; Cell Line; Humans; Neuroblastoma; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured | 1989 |
Temporal relationship between A1 adenosine receptor upregulation and alterations in bicuculline seizure susceptibility in rats.
Topics: Adenosine; Animals; Bicuculline; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Seizures; Theophylline; Time Factors | 1989 |
Mechanisms involved in the action of prostaglandins as modulators of neurotransmission.
Topics: Acetylcholine; Adenosine; Animals; Blood Pressure; Dilazep; Electric Stimulation; Female; Heart Rate; In Vitro Techniques; Indomethacin; Kidney; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Prostaglandins; Rabbits; Theophylline; Xanthines | 1989 |
Characterization of human adipocyte adenosine receptors.
Topics: Adenosine; Adipose Tissue; Binding, Competitive; Cell Membrane; Cross-Linking Reagents; Humans; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Photochemistry; Receptors, Purinergic; Theophylline | 1989 |
Forskolin potentiates myocardial reactive hyperaemia in the open chest dog: the contribution of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Animals; Colforsin; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Hyperemia; Myocardium; Theophylline; Time Factors | 1989 |
Doxofylline, an adenosine-nonblocking xanthine, does not induce cardiostimulant effects.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Cardiotonic Agents; Cats; Electric Stimulation; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Theophylline | 1989 |
Postnatal changes in response to adenosine and adenine nucleotides in rat duodenum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Duodenum; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1989 |
Characterization of adenosine receptors in guinea-pig isolated left atria.
Topics: Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium Radioisotopes; Dipyridamole; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Receptors, Purinergic; Rubidium Radioisotopes; Theophylline | 1989 |
Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1 and A2 receptors in isolated tissues from guinea-pigs.
Topics: Adenosine; Animals; Aorta, Thoracic; Binding, Competitive; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Receptors, Purinergic; Theophylline; Trachea; Xanthines | 1989 |
Canine coronary vasodepressor responses to hypoxia are abolished by 8-phenyltheophylline.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart; Heart Rate; Hypoxia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Theophylline; Vascular Resistance | 1989 |
Role of adenosine in the gastric blood flow response to pentagastrin in the rat.
Topics: Adenosine; Animals; Gastric Acid; Gastric Mucosa; Male; Pentagastrin; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline; Vasodilation | 1989 |
Modulation of stimulation-evoked release of newly formed acetylcholine from mouse hemidiaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Aminopyridines; Animals; Atropine; Calcium; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Mice; Neuromuscular Junction; Oxotremorine; Tetrodotoxin; Theophylline; Xylazine | 1987 |
On the role, inactivation and origin of endogenous adenosine at the frog neuromuscular junction.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dipyridamole; In Vitro Techniques; Motor Endplate; Neuromuscular Junction; Nucleotidases; Rana ridibunda; Synaptic Transmission; Theophylline | 1987 |
On the nature of endogenous purines modulating cholinergic neurotransmission in the guinea-pig ileum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; AMP Deaminase; Animals; Cholinergic Fibers; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Purines; Synaptic Transmission; Theophylline | 1987 |
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; Bone Resorption; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cyclic AMP; Rolipram; Theophylline | 1987 |
Effect of phenylisopropyladenosine on vasopressin-dependent cyclic AMP generation in defined nephron segments from rat.
Topics: Adenosine; Animals; Cyclic AMP; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Kidney Tubules, Distal; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline; Vasopressins | 1987 |
Endogenous adenosine modulates gastric acid secretion to histamine in canine parietal cells.
Topics: Adenosine; Adenosine Deaminase; Animals; Bucladesine; Carbachol; Dipyridamole; Dogs; Female; Gastric Acid; Histamine; Male; Parietal Cells, Gastric; Receptors, Purinergic; Theophylline | 1988 |
Participation of prostaglandin E2 in the purinergic neurotransmission of gut.
Topics: Adenine Nucleotides; Adenosine; Animals; Apamin; Dinoprostone; Dipyridamole; Female; Guinea Pigs; Ileum; Indomethacin; Male; Muscle, Smooth; Prostaglandins E; Receptors, Purinergic; Synaptic Transmission; Synaptosomes; Theophylline | 1987 |
Stimulation of glycogenolysis and vasoconstriction by adenosine and adenosine analogues in the perfused rat liver.
Topics: Adenosine; Animals; Calcium; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Indomethacin; Liver; Liver Glycogen; Male; Phosphorylase a; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Vasoconstriction | 1987 |
Changes in adenosine receptors during differentiation of 3T3-F442A cells to adipocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Imidazoles; Isoproterenol; Mice; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1988 |
Histamine or adenosine blockade alters intestinal blood flow autoregulation in swine.
Topics: Adenosine; Animals; Chlorpheniramine; Homeostasis; Intestines; Receptors, Cell Surface; Receptors, Histamine; Receptors, Histamine H1; Regional Blood Flow; Renal Circulation; Swine; Theophylline | 1988 |
Adenosine promotes neutrophil chemotaxis.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Chemotaxis, Leukocyte; Drug Synergism; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Stimulation, Chemical; Superoxides; Theophylline; Zymosan | 1988 |
L-phenylisopropyladenosine (L-PIA) diminishes halothane anesthetic requirements and decreases noradrenergic neurotransmission in rats.
Topics: Adenosine; Anesthesia; Animals; Brain; Halothane; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1988 |
Evidence for A2 adenosine receptor-mediated effects on adenylate cyclase activity in rat ovarian membranes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cell Membrane; Cyclic AMP; Female; Follicle Stimulating Hormone; Ovary; Rats; Receptors, Purinergic; Theophylline | 1988 |
Evidence for adenosine A1 receptor action in rat jejunal mucosa.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Intestinal Mucosa; Jejunum; Male; Papaverine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1988 |
Presynaptic P1-purinoceptors in jejunal branches of the rabbit mesenteric artery and their possible function.
Topics: Action Potentials; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Guanosine; In Vitro Techniques; Jejunum; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Rabbits; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Thionucleosides | 1988 |
Effect of heptaminol AMP amidate, a new nucleotide derivative, on in vitro humoral immunity.
Topics: Adenosine; Adenosine Monophosphate; Amino Alcohols; Animals; Antibody Formation; Bucladesine; Cells, Cultured; Drug Interactions; Heptaminol; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Theophylline | 1988 |
Presynaptic inhibition of sympathetic fibers participating in vasodilatation in response to K+-induced contraction of frog skeletal muscle.
Topics: Adenosine; Animals; Arterioles; Biological Transport; Dipyridamole; Muscle Contraction; Muscle, Smooth, Vascular; Muscles; Phentolamine; Potassium; Rana temporaria; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synapses; Theophylline; Vasodilation | 1988 |
Effect of calcium dobesilate on platelet function.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Benzenesulfonates; Calcium Dobesilate; Collagen; Cricetinae; Cyclic AMP; Drug Interactions; Platelet Aggregation Inhibitors; Prostaglandins E; Rabbits; Serotonin; Theophylline; Thrombin | 1988 |
Presynaptic actions of carbachol and adenosine on corticostriatal synaptic transmission studied in vitro.
Topics: Action Potentials; Adenosine; Animals; Atropine; Carbachol; Cerebral Cortex; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Kynurenic Acid; Neural Pathways; Rats; Rats, Inbred Strains; Synaptic Transmission; Tetrodotoxin; Theophylline | 1988 |
Neuropeptide Y action in the rat hippocampal slice: site and mechanism of presynaptic inhibition.
Topics: Acetylcholine; Action Potentials; Adenosine; Animals; Atropine; Barium; Bicuculline; Calcium; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Neuropeptide Y; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Purinergic; Theophylline | 1988 |
Modulation of neuronal excitability by endogenous adenosine in the absence of synaptic transmission.
Topics: Action Potentials; Adenosine; Animals; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Synaptic Transmission; Temperature; Theophylline | 1988 |
Antagonism by clonidine of the adenosine-induced inhibition of the twitch contraction of the guinea-pig Oddi sphincter.
Topics: Adenosine; Alprostadil; Ampulla of Vater; Animals; Clonidine; Dipyridamole; Electric Stimulation; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Prostaglandins E; Reserpine; Sphincter of Oddi; Theophylline; Yohimbine | 1985 |
Inhibition of [3H] glutamate release from rat hippocampal slices by L-phenylisopropyladenosine.
Topics: Adenosine; Animals; Calcium; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Tetrodotoxin; Theophylline | 1985 |
Adenosine induced production of a soluble factor affecting lymphocyte activation.
Topics: Adenosine; Humans; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Suppressor Factors, Immunologic; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Theophylline | 1986 |
The adenosine receptor antagonist, 8-phenyltheophylline, causes diuresis and saliuresis in the rat.
Topics: Adenosine; Animals; Diuresis; Heart Rate; Rats; Rats, Inbred Strains; Receptors, Purinergic; Salts; Theophylline; Xanthines | 1986 |
Adenosine stimulates guanylate cyclase activity in vascular smooth muscle cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Theophylline; Time Factors | 1987 |
Pentobarbital antagonizes the A1 adenosine receptor-mediated inhibition of hippocampal neurotransmitter release.
Topics: Acetylcholine; Adenosine; Animals; Dose-Response Relationship, Drug; Hippocampus; Neurotransmitter Agents; Norepinephrine; Pentobarbital; Rabbits; Receptors, Purinergic; Theophylline | 1987 |
Central effects of adenosine analogs on stress-induced gastric ulcer formation.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Injections, Intraventricular; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Stomach Ulcer; Stress, Physiological; Theophylline | 1987 |
Neural control of shark rectal gland.
Topics: Adenosine; Animals; Bucladesine; Dogfish; Female; In Vitro Techniques; Male; Oxygen Consumption; Perfusion; Procaine; Salt Gland; Sharks; Somatostatin; Tetrodotoxin; Theophylline; Vasoactive Intestinal Peptide; Veratrine | 1988 |
Excitatory P1-purinoceptors on pre- and post-ganglionic cholinergic nerve terminals in the chick oesophagus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Chickens; Esophagus; Female; Male; Nerve Endings; Receptors, Cholinergic; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1988 |
Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Alprostadil; Bucladesine; Butyrates; Butyric Acid; Cell Division; Cyclic AMP; Dinoprostone; Enzyme Induction; Humans; Leukemia, Myeloid; Theophylline; Transglutaminases; Tretinoin; Tumor Cells, Cultured | 1988 |
Dual effects of theophylline on spontaneous transmitter release from frog motor nerve terminals.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Isotonic Solutions; Neuromuscular Junction; Neurotransmitter Agents; Phosphodiesterase Inhibitors; Rana pipiens; Receptors, Purinergic; Ringer's Solution; Theophylline; Xanthines | 1988 |
Characterization of adenosine receptors in human pulmonary arteries.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adult; Dose-Response Relationship, Drug; Humans; Middle Aged; Phenylisopropyladenosine; Pulmonary Artery; Receptors, Purinergic; Theophylline; Vasodilation | 1989 |
Role of endogenous adenosine in recurrent generalized seizures.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Cats; Cerebral Cortex; Dipyridamole; Doxapram; Naloxone; Penicillins; Receptors, Purinergic; Reference Values; Seizures; Theophylline | 1989 |
Downregulation and desensitization of A1-adenosine receptors in embryonic chicken heart.
Topics: Adenosine; Animals; Carbachol; Cell Membrane; Chick Embryo; Heart; Kinetics; Myocardium; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1989 |
Effect of theophylline on adenosine-induced bronchoconstriction.
Topics: Adenosine; Adolescent; Adult; Bronchial Diseases; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Theophylline | 1989 |
Effect of inosine on pial arterioles: potentiation of adenosine-induced vasodilation.
Topics: Adenosine; Animals; Arteries; Arterioles; Cerebrovascular Circulation; Drug Synergism; Inosine; Male; Muscle, Smooth, Vascular; Pia Mater; Rats; Rats, Inbred Strains; Theophylline; Vasodilation; Venules | 1989 |
Mechanisms underlying the supra-maximal thermogenesis elicited by aminophylline in rats.
Topics: Adenosine; Aminophylline; Animals; Body Temperature Regulation; Cold Temperature; Drug Synergism; Male; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Endogenous adenosine improves work rate to oxygen consumption ratio in catecholamine stimulated isovolumic rat heart.
Topics: Adenosine; Adenosine Deaminase; Animals; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardium; Norepinephrine; Nucleoside Deaminases; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Amrinone potentiates catecholamine-induced lipolysis in fat cells.
Topics: Adenosine; Adipose Tissue; Amrinone; Animals; Calcium; Lipolysis; Male; Norepinephrine; Rats; Rats, Inbred Strains; Theophylline | 1989 |
[Dilator effects of adenosine on rat pancreatic vessels].
Topics: Adenosine; Animals; In Vitro Techniques; Kinetics; Pancreas; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1985 |
Adenosine-induced bronchoconstriction in the guinea-pig isolated lung: interaction with theophylline and enprofylline.
Topics: Adenosine; Animals; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; In Vitro Techniques; Lung; Male; Theophylline; Xanthines | 1988 |
Evidence suggesting an Ra-type adenosine receptor in bovine coronary arteries.
Topics: Adenosine; Adenosine Deaminase; Animals; Cattle; Coronary Vessels; Inosine; Pentosyltransferases; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Norepinephrine and histamine potentiate the increases in cyclic adenosine 3':5'-monophosphate elicited by vasoactive intestinal polypeptide in mouse cerebral cortical slices: mediation by alpha 1-adrenergic and H1-histaminergic receptors.
Topics: Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Histamine; Male; Mice; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Histamine H1; Serotonin; Theophylline; Vasoactive Intestinal Peptide | 1985 |
A1 and A2 adenosine receptor activation inhibits and stimulates renin secretion of rat renal cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Egtazic Acid; Gallopamil; In Vitro Techniques; Kidney Cortex; Male; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Renin; Theophylline; Vanadates; Vanadium | 1985 |
Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Esterases; Homocysteine; Kinetics; Lysosomes; Macrophages; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Structure-Activity Relationship; Theophylline; Tubercidin | 1985 |
Adenosine-induced depression of synaptic transmission in the isolated olfactory cortex: receptor identification.
Topics: Adenosine; Animals; Central Nervous System; Colforsin; Cyclic AMP; Diterpenes; Evoked Potentials; Female; Guinea Pigs; Intracellular Membranes; Male; Norepinephrine; Olfactory Pathways; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline | 1985 |
Actions of enprofylline in the rat hippocampus.
Topics: Adenosine; Animals; Bronchodilator Agents; Cyclic AMP; Evoked Potentials; Felodipine; Hippocampus; Isoproterenol; Male; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Theophylline; Trifluoperazine; Xanthines | 1985 |
Cyclic AMP concentrations in rat neocortex and hippocampus during and following incomplete ischemia: effects of central noradrenergic neurons, prostaglandins, and adenosine.
Topics: Adenosine; Animals; Brain Ischemia; Cerebral Cortex; Cyclic AMP; Energy Metabolism; Fatty Acids, Nonesterified; Glycolysis; Hippocampus; Indomethacin; Locus Coeruleus; Male; Norepinephrine; Prostaglandins; Rats; Theophylline | 1985 |
On the mechanism of action of theophylline and caffeine.
Topics: Adenosine; Asthma; Caffeine; Calcium; Cyclic AMP; Humans; Muscle Contraction; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Adenosine modulation of synaptic responses in rat hippocampus: possible role of inhibition or activation of adenylate cyclase.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Cyclic AMP; Enzyme Activation; Hippocampus; In Vitro Techniques; Kinetics; Membrane Potentials; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Synaptic Membranes; Tetrodotoxin; Theophylline | 1985 |
On the type of receptor involved in the inhibitory action of adenosine at the neuromuscular junction.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; In Vitro Techniques; Neuromuscular Junction; Phenylisopropyladenosine; Rana ridibunda; Receptors, Cell Surface; Receptors, Purinergic; Synaptic Transmission; Theophylline | 1985 |
Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Binding, Competitive; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Cell Surface; Receptors, Purinergic; Superoxides; Theophylline | 1985 |
[Study of stereoisomers of N6-phenylisopropyladenosine on the secretion of pancreatic glucagon].
Topics: Adenosine; Animals; Glucagon; In Vitro Techniques; Pancreas; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic; Stereoisomerism; Theophylline; Time Factors | 1985 |
Adenosine-activated potassium conductance in cultured striatal neurons.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Cell Membrane; Cells, Cultured; Corpus Striatum; Electric Conductivity; Evoked Potentials; Mice; Neurons; Potassium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
PACPX--a substituted xanthine--antagonizes both the A1 and A2 subclasses of the P1-purinoceptor: antagonism of the A2 subclass is competitive but antagonism of the A1 subclass is not.
Topics: Adenosine; Animals; Binding, Competitive; Colon; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Xanthines | 1985 |
Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
Topics: Adenosine; Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Esterification; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthenes; Xanthines | 1985 |
Specific photoaffinity labelling of inhibitory adenosine receptors.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Affinity Labels; Animals; Azides; Cerebellum; Chickens; Guanylyl Imidodiphosphate; Phenylisopropyladenosine; Photochemistry; Receptors, Cell Surface; Receptors, Purinergic; Synaptic Membranes; Theophylline | 1985 |
Further evidence for involvement of adenosine-5'-triphosphate in non-adrenergic non-cholinergic relaxation of the isolated rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomic Nervous System; Chymotrypsin; Duodenum; gamma-Aminobutyric Acid; Male; Muscle Relaxation; Muscle, Smooth; Potassium; Pyrophosphatases; Rats; Rats, Inbred Strains; Theophylline | 1985 |
Theophylline-sensitive modulation of non-cholinergic excitatory neurotransmission in the guinea-pig ileum.
Topics: Adenosine; Animals; Atropine; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Synaptic Transmission; Theophylline | 1985 |
Antagonism by theophylline of the adenosine receptor agonist 5'-N-ethylcarboxamidoadenosine at the guinea pig ileum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1985 |
Possible role of adenosine in the macula densa mechanism of renin release in rabbits.
Topics: Adenosine; Animals; Arterioles; Depression, Chemical; Epithelium; Juxtaglomerular Apparatus; Kidney Tubules; Kidney Tubules, Distal; Male; Organ Culture Techniques; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Renin; Theophylline | 1985 |
Evidence for an A2-subtype adenosine receptor on pancreatic glucagon secreting cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Glucagon; In Vitro Techniques; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Theophylline | 1985 |
Evidence for an A2 adenosine receptor in guinea pig lung.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Ligands; Lung; Membranes; Pyrrolidinones; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline; Time Factors | 1985 |
Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Nalorphine; Norepinephrine; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Dual effects of adenosine and adenosine analogues on motor activity of the human fallopian tube.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Fallopian Tubes; Female; Humans; Lidocaine; Menstruation; Middle Aged; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1985 |
Evidence for adenosine receptor-mediated isoprenaline-antagonistic effects of the adenosine analogs PIA and NECA on force of contraction in guinea-pig atrial and ventricular cardiac preparations.
Topics: Action Potentials; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Dipyridamole; Female; Guinea Pigs; Heart Atria; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Ouabain; Papillary Muscles; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Accumulations of inositol phosphates and cyclic AMP in brain slices: synergistic interactions of histamine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Receptors, Cell Surface; Receptors, Purinergic; Sugar Phosphates; Theophylline | 1986 |
Adenosine inhibits locus coeruleus neurons: an intracellular study in a rat brain slice preparation.
Topics: Adenosine; Animals; Depression, Chemical; Electric Conductivity; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Adenosine receptors in papilla of human kidneys.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Enzyme Induction; Humans; Kidney Medulla; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Histamine; Isoproterenol; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
Adenosine inhibits epileptiform activity arising in hippocampal area CA3.
Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Enzyme Induction; Epilepsy; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Purinergic; Synaptosomes; Theophylline | 1986 |
Evidence against functional adenosine receptors on murine lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Male; Mice; Mitogens; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Arylazido aminopropionyl ATP (ANAPP3): interaction with adenosine receptors in longitudinal smooth muscle of the guinea-pig ileum.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Azides; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Pharmacological characterization of the receptor involved in chemoexcitation induced by adenosine.
Topics: Adenosine; Animals; Carotid Body; Cats; Hypoxia; Receptors, Cell Surface; Receptors, Purinergic; Stimulation, Chemical; Theophylline; Xanthines | 1986 |
Classification of adenosine receptors mediating antinociception in the rat spinal cord.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Male; Pain; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Spinal Cord; Theophylline | 1986 |
Purinergic modulation of the seizure threshold for pentylenetetrazol in the rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Kinetics; Male; Pentylenetetrazole; Phenylisopropyladenosine; Purines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline | 1985 |
Calcium entry blocking activity of dilazep in dog coronary artery.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Arteries; Azepines; Calcium; Calcium Channel Blockers; Coronary Vessels; Dilazep; Diltiazem; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lidoflazine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
Adenosine receptors on human lymphocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alprostadil; Binding Sites; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Histamine; Humans; In Vitro Techniques; Isoproterenol; Lymphocytes; Manganese; Neutrophils; Receptors, Purinergic; Theophylline; Vidarabine | 1986 |
The effects of adenosine agonists on human neutrophil function.
Topics: Adenosine; Cytoplasmic Granules; Exocytosis; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Superoxides; Theophylline | 1986 |
Qualitative differences in the effects of adenosine analogs on the cholinergic systems of rat striatum and hippocampus.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Corpus Striatum; Female; Glutamates; Hippocampus; In Vitro Techniques; Parasympathetic Nervous System; Parasympathomimetics; Phenylisopropyladenosine; Rats; Synaptic Transmission; Theophylline | 1986 |
Effects of adenosine and adenosine analogues on glycogen metabolism in isolated rat hepatocytes.
Topics: Adenosine; Animals; Cladribine; Cyclic AMP; Deoxyadenosines; Enzyme Activation; Glucose; Glycogen; Kinetics; Liver; Male; Phosphorylase a; Phosphorylase b; Rats; Rats, Inbred Strains; Theophylline | 1986 |
The inhibitory effects of some adenosine analogues on transmitter release at the mammalian neuromuscular junction.
Topics: 2-Chloroadenosine; Adenosine; Animals; In Vitro Techniques; Membrane Potentials; Mice; Neuromuscular Junction; Receptors, Purinergic; Synaptic Transmission; Theophylline | 1986 |
Effects of papaverine and theophylline on renal adenosine transport.
Topics: Adenosine; Animals; Biological Transport, Active; Cyclic AMP; Dipyridamole; Guanosine; Kidney; Male; Papaverine; Perfusion; Rats; Rats, Inbred Strains; Theophylline | 1986 |
Isolated rectal gland cells: oxygen consumption and hormonal stimulation.
Topics: Adenosine; Animals; Bucladesine; Chlorides; Dogfish; Hormones; Microscopy, Phase-Contrast; Monensin; Ouabain; Oxygen Consumption; Salt Gland; Sharks; Theophylline; Vasoactive Intestinal Peptide | 1986 |
[Uptake of cyclic adenosine-3,5-monophosphate by cultured mammalian cells and frog muscles].
Topics: Adenosine; Animals; Cell Line; Cells, Cultured; Chromatography, Ion Exchange; Chromatography, Paper; Cyclic AMP; In Vitro Techniques; Mice; Muscles; Rana temporaria; Theophylline; Tritium | 1986 |
An increase of tissue cyclic AMP level by adenosine in the dog pancreas without stimulation of exocrine secretion.
Topics: Adenosine; Animals; Cyclic AMP; Dogs; Female; In Vitro Techniques; Male; Pancreas; Secretin; Theophylline | 1987 |
Inhibition of renin release by analogues of adenosine in rabbit renal cortical slices.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Deoxyadenosines; Isomerism; Isoproterenol; Kidney Cortex; Male; Phenylisopropyladenosine; Rabbits; Receptors, Adrenergic, beta; Renin; Theophylline | 1987 |
The cardiac anti-adrenergic effect of adenosine.
Topics: Adenosine; Animals; Feedback; Heart; Models, Biological; Myocardial Contraction; Phosphorylases; Protein Kinases; Receptors, Adrenergic, beta; Theophylline | 1987 |
Functional evidence for adenosine A2 receptor regulation of phosphatidylcholine secretion in cultured type II pneumocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Male; Phenylisopropyladenosine; Phosphatidylcholines; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Theophylline | 1987 |
Role of adenosine in regulation of cerebral blood flow: effects of theophylline during normoxia and hypoxia.
Topics: Adenosine; Animals; Brain; Cerebrovascular Circulation; Cyclic AMP; Hypoxia; Osmolar Concentration; Pia Mater; Rats; Reference Values; Theophylline | 1987 |
Central versus peripheral mediation of responses to adenosine receptor agonists: evidence against a central mode of action.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Hippocampus; Injections, Intraperitoneal; Injections, Spinal; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1987 |
[Theophylline-induced changes in the presynaptic effects of adenosine, baclofen, clofelin and morphine in the myenteric plexus of the guinea pig].
Topics: Adenosine; Animals; Baclofen; Clonidine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Myenteric Plexus; Receptors, Cholinergic; Receptors, Neurotransmitter; Theophylline | 1987 |
Effect of adenosine on the formation of prostacyclin in the rabbit isolated heart.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Aorta; Coronary Circulation; Epoprostenol; Female; Heart; In Vitro Techniques; Male; Myocardium; Perfusion; Rabbits; Theophylline | 1988 |
Effect of hypoxia on nerve-stimulation-induced release of noradrenaline from the rabbit heart.
Topics: Adenosine; Animals; Electric Stimulation; Epoprostenol; Female; Heart; Hypoxia; Indomethacin; Male; Myocardium; Norepinephrine; Rabbits; Sympathetic Nervous System; Theophylline | 1988 |
Effect of theophylline on adenosine production in the canine myocardium.
Topics: Adenosine; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Coronary Circulation; Dogs; Female; Heart; Hydrogen-Ion Concentration; Isoproterenol; Male; Myocardium; Oxygen; Oxygen Consumption; Partial Pressure; Theophylline; Vascular Resistance | 1987 |
The adenosine receptor-mediated inhibition of noradrenaline release possibly involves an N-protein and is increased by alpha 2-autoreceptor blockade.
Topics: Adenosine; Animals; Electric Stimulation; Ethylmaleimide; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Norepinephrine; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Theophylline; Yohimbine | 1987 |
Assessment of purine-dopamine interactions in 6-hydroxydopamine-lesioned rats: evidence for pre- and postsynaptic influences by adenosine.
Topics: Adenosine; Animals; Female; Hydroxydopamines; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Levodopa; Motor Activity; Oxidopamine; Pregnancy; Purines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Theophylline | 1988 |
Psychomotor stimulant effects of methylxanthines in squirrel monkeys: relation to adenosine antagonism.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Male; Psychomotor Performance; Receptors, Purinergic; Saimiri; Stimulation, Chemical; Theophylline; Xanthines | 1988 |
P1-purinoceptors in the cerebrovascular bed of the goat in vivo.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Goats; Heart Rate; Muscle Tonus; Oxygen Consumption; Receptors, Purinergic; Theophylline; Vasodilation | 1988 |
Cerebral blood flow and interstitial fluid adenosine during hemorrhagic hypotension.
Topics: Adenosine; Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Dialysis; Extracellular Space; Hemorrhage; Homeostasis; Hypotension; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Vascular Resistance | 1988 |
The effects of dipyridamole and theophylline on rat pial vessels during hypocarbia.
Topics: Adenosine; Animals; Carbon Dioxide; Dipyridamole; Male; Pia Mater; Rats; Theophylline; Vasoconstriction | 1988 |
Theophylline antagonizes the effect of diazepam on ventricular automaticity.
Topics: Adenosine; Animals; Diazepam; Female; Flumazenil; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Theophylline; Ventricular Function | 1988 |
Inhibition of rat ventricular automaticity by adenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Atropine; Depression, Chemical; Electric Stimulation; Electrocardiography; Heart Rate; Heart Ventricles; Male; Propranolol; Rats; Rats, Inbred Strains; Stereoisomerism; Systole; Theophylline | 1985 |
Involvement of P1-purinoreceptors in the relaxing effect of adenosine in rat duodenum.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1988 |
The potential role of adenosine in regulating blood flow in the eye.
Topics: Adenosine; Animals; Dipyridamole; Eye; Female; Lasers; Papaverine; Rabbits; Regional Blood Flow; Theophylline | 1988 |
Mediation of acute ethanol-induced motor disturbances by cerebellar adenosine in rats.
Topics: Adenosine; Animals; Cerebellum; Dilazep; Dose-Response Relationship, Drug; Ethanol; Male; Motor Activity; Motor Skills; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline | 1988 |
3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred DBA; Motor Activity; Reference Values; Theobromine; Theophylline | 1988 |
Characterization of prejunctional purinoceptors on adrenergic nerves of the rat caudal artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Arteries; Azides; Electric Stimulation; Male; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline | 1988 |
Interactions of adenosine and magnesium on rat hippocampal slices.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Drug Interactions; Electric Stimulation; Hippocampus; In Vitro Techniques; Magnesium; Rats; Theophylline | 1988 |
Negative and positive influences exerted by purine compounds on isolated guinea-pig atria.
Topics: Adenine Nucleotides; Adenosine; Animals; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Purines; Receptors, Purinergic; Theophylline | 1988 |
Pharmacological classification of receptors for adenyl purines in guinea pig myometrium.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Azides; Female; Guanosine; Guinea Pigs; Myometrium; Phenylisopropyladenosine; Receptors, Purinergic; Stereoisomerism; Theophylline; Thionucleosides | 1988 |
Endothelium-dependent contraction and -independent relaxation induced by adenine nucleotides and nucleoside in the canine basilar artery.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Basilar Artery; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Male; Theophylline; Thromboxane A2; Vasoconstriction; Vasodilation | 1988 |
Gastric motor responses elicited by vagal stimulation and purine compounds in the atropine-treated rabbit.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Blood Pressure; Electric Stimulation; Female; Gastrointestinal Motility; Purines; Rabbits; Theophylline; Triazines; Vagus Nerve | 1988 |
Evidence that cholinergic axon terminals are equipped with both muscarinic and adenosine receptors.
Topics: Acetylcholine; Adenosine; Animals; Atropine; Axons; Dipyridamole; Female; Guinea Pigs; Male; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Receptors, Muscarinic; Receptors, Purinergic; Theophylline | 1988 |
Mediation by adenosine of bradycardia in rat heart during graded global ischaemia.
Topics: Adenosine; Animals; Atrioventricular Node; Bradycardia; Coronary Disease; Heart Rate; In Vitro Techniques; Male; Rats; Receptors, Purinergic; Sinoatrial Node; Theophylline | 1988 |
Adenosine modulation of vasoconstrictor responses to stimulation of sympathetic nerves and norepinephrine infusion in the superior mesenteric artery of the cat.
Topics: Adenosine; Animals; Cats; Electric Stimulation; Female; Injections, Intra-Arterial; Isoproterenol; Male; Mesenteric Arteries; Norepinephrine; Sympathetic Nervous System; Theophylline; Vasoconstriction; Vasodilation | 1988 |
Vascular escape from vasoconstriction and post-stimulatory hyperemia in the superior mesenteric artery of the cat.
Topics: Adenosine; Animals; Cats; Electric Stimulation; Female; Hyperemia; Male; Mesenteric Arteries; Norepinephrine; Ouabain; Propranolol; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1988 |
Adenosine as a modulator of sympathetic nerve-stimulation-induced release of noradrenaline from the isolated rabbit heart.
Topics: Adenosine; Animals; Electric Stimulation; Female; Heart; Male; Myocardial Contraction; Norepinephrine; Rabbits; Receptors, Purinergic; Sympathetic Nervous System; Theophylline | 1988 |
Doxofylline and theophylline are xanthines with partly different mechanisms of action in animals.
Topics: Adenosine; Aminophylline; Animals; Diuresis; Gastric Acid; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Natriuresis; Rats; Rats, Inbred Strains; Reference Values; Theophylline; Trachea | 1988 |
Parasympathetic depression of vas deferens contraction in the guinea-pig involves adenosine receptors.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Parasympathetic Nervous System; Pelvis; Receptors, Purinergic; Sympathetic Nervous System; Theophylline; Time Factors; Vas Deferens | 1988 |
ATP and other adenine compounds increase mechanical activity and inositol trisphosphate production in rat heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Atropine; Female; Heart; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Myocardial Contraction; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sugar Phosphates; Sympatholytics; Theophylline | 1988 |
Adenosine is required for myocardial insulin responsiveness in vivo.
Topics: Adenosine; Animals; Dogs; Female; Glucose; Insulin; Insulin Antagonists; Male; Myocardium; Receptors, Purinergic; Theophylline | 1988 |
[Receptors for the secretory component on human thymic lymphocytes. Stimulation of their expression as affected by adenosine, theophylline and a thymic lymphocyte supernatant].
Topics: Adenosine; Adolescent; Cell Extracts; Child; Child, Preschool; Colostrum; Female; Fluorescent Antibody Technique; Heart Defects, Congenital; Humans; Immunoglobulin A; Immunoglobulin A, Secretory; Immunoglobulin Fragments; Receptors, Immunologic; Secretory Component; T-Lymphocytes; Theophylline; Tissue Extracts | 1987 |
The selective response to adenosine of renal microvessels from hamster explants.
Topics: Adenosine; Animals; Arteries; Arterioles; Cheek; Cricetinae; Kidney Cortex; Mesocricetus; Microcirculation; Renin-Angiotensin System; Theophylline; Vasoconstriction | 1988 |
Adenosine effects on hormone-stimulated steroidogenesis in isolated bovine adrenal zona fasciculata cells.
Topics: Adenosine; Adenosine Deaminase; Adrenal Cortex; Animals; Cattle; Cosyntropin; Hydrocortisone; In Vitro Techniques; Kinetics; Phenylisopropyladenosine; Theophylline | 1988 |
Role of adenosine in coronary vasodilation during exercise.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Blood Volume; Coronary Circulation; Heart Rate; Myocardium; Oxygen Consumption; Physical Exertion; Theophylline; Vasodilation | 1988 |
Contractile effect of succinylpurines on guinea pig uterus.
Topics: Adenosine; Animals; Dipyridamole; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Receptors, Purinergic; Theophylline; Uterine Contraction | 1988 |
125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Affinity Labels; Algorithms; Animals; Binding, Competitive; Brain; Cattle; Humans; Iodine Radioisotopes; Iodobenzenes; Isotope Labeling; Kinetics; Ligands; Membranes; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Chloride; Structure-Activity Relationship; Theophylline; Xanthines | 1988 |
Propentofylline (HWA 285) protects hippocampal neurons of Mongolian gerbils against ischemic damage in the presence of an adenosine antagonist.
Topics: Adenosine; Animals; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Pyramidal Tracts; Reference Values; Theophylline; Xanthines | 1988 |
Ethanol-induced increase in portal blood flow: role of adenosine.
Topics: Adenosine; Animals; Cardiac Output; Ethanol; Kinetics; Male; Organ Specificity; Portal System; Rats; Rats, Inbred Strains; Receptors, Purinergic; Regional Blood Flow; Theophylline; Vascular Resistance | 1988 |
Adenosine and leukotrienes have a regulatory role in lung surfactant secretion in the newborn rabbit.
Topics: Adenosine; Animals; Animals, Newborn; Atropine; Chromones; Phospholipids; Pilocarpine; Pulmonary Surfactants; Rabbits; Receptors, Purinergic; SRS-A; Theophylline | 1988 |
Influence of epithelium on the responsiveness of guinea-pig isolated trachea to adenosine.
Topics: Adenosine; Animals; Dipyridamole; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle, Smooth; Theophylline; Trachea | 1988 |
Myocardial reactive hyperemia in the newborn.
Topics: Adenosine; Cerebrovascular Circulation; Dipyridamole; Humans; Hyperemia; Infant, Newborn; Myocardium; Oxygen Consumption; Theophylline | 1988 |
Tolerance and cross-tolerance to theophylline-induced stimulation of locomotor activity in rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Dextroamphetamine; Drug Tolerance; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline | 1988 |
Pharmacological basis and therapeutic efficacy of flunarizine in peripheral artery disease.
Topics: Adenosine; Aged; Calcium Channel Blockers; Female; Flunarizine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neutrophils; Theophylline; Vascular Diseases | 1988 |
Endogenous intrarenal adenosine preserves renal blood flow in one-kidney, one clip rats.
Topics: Adenosine; Angiotensin II; Animals; Atenolol; Blood Pressure; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains; Renal Circulation; Saralasin; Theophylline; Vascular Resistance | 1988 |
The response of isolated guinea-pig aorta to amrinone.
Topics: Adenosine; Adenosine Deaminase; Amrinone; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Quinidine; Theophylline | 1988 |
A1 and A2 adenosine receptor regulation of erythropoietin production.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Albuterol; Animals; Erythrocytes; Erythropoietin; Female; Hypoxia; Iron Radioisotopes; Mice; Mice, Inbred ICR; Polycythemia; Receptors, Purinergic; Theophylline | 1988 |
A reexamination of the effects induced by adenosine and its degradation products on rat fat cell lipolysis.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lipid Mobilization; Norepinephrine; Rats; Theophylline; Uric Acid | 1988 |
Dynamic cerebral and systemic circulatory effects of adenosine, theophylline and dipyridamole.
Topics: Adenosine; Animals; Blood Pressure; Cerebrovascular Circulation; Dipyridamole; Injections, Intravenous; Male; Rabbits; Receptors, Purinergic; Theophylline | 1988 |
Theophylline prevents the hypoxemia-induced renal hemodynamic changes in rabbits.
Topics: Adenosine; Animals; Animals, Newborn; Glomerular Filtration Rate; Hypoxia; Kidney; Rabbits; Renal Circulation; Theophylline | 1988 |
Adenosine plays a role in food-induced jejunal hyperemia.
Topics: Adenosine; Aminophylline; Animals; Dogs; Eating; Female; Gastrointestinal Motility; Jejunum; Kinetics; Male; Oxygen Consumption; Regional Blood Flow; Theophylline | 1988 |
Chronic theophylline exposure increases agonist and antagonist binding to A1 adenosine receptors in rat brain.
Topics: Adenosine; Animals; Brain; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1988 |
Influence of purinoceptors' agonists and antagonists on opossum internal anal sphincter.
Topics: Adenosine; Adenosine Triphosphate; Anal Canal; Animals; Electric Stimulation; Female; Male; Opossums; Receptors, Purinergic; Reference Values; Theophylline | 1988 |
Effects of adenosine and its analogues on porcine basilar arteries: are only A2 receptors involved?
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Basilar Artery; Dinoprost; Dose-Response Relationship, Drug; Phenylisopropyladenosine; Prostaglandins F; Receptors, Purinergic; Swine; Theophylline; Vasodilation; Vasodilator Agents | 1988 |
Moderate hypoxia: reactivity of pial arteries and local effect of theophylline.
Topics: Adenosine; Animals; Cats; Cerebral Arteries; Female; Hypoxia; Infusions, Intravenous; Male; Theophylline; Vasodilation | 1987 |
Interdependence of spinal adenosinergic, serotonergic and noradrenergic systems mediating antinociception.
Topics: Adenosine; Animals; Clonidine; Male; Methysergide; Mice; Nociceptors; Norepinephrine; Phentolamine; Reaction Time; Serotonin; Spinal Cord; Theophylline | 1987 |
Elevation of intrarenal adenosine by maleic acid decreases GFR and renin release.
Topics: Adenosine; Animals; Depression, Chemical; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Maleates; Renal Circulation; Renin; Sodium; Stimulation, Chemical; Theophylline | 1986 |
Chronic administration of theophylline to rats induces a post-insulin binding defect in adipocyte glucose transport.
Topics: Adenosine; Adipose Tissue; Animals; Binding Sites; Biological Transport; Glucose; Insulin; Male; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Purinergic; Theophylline | 1987 |
Further characterization of the renovascular effects of N6-cyclohexyladenosine in the isolated perfused rat kidney.
Topics: Adenosine; Animals; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1987 |
Effects of adenosine infusion into renal interstitium on renal hemodynamics.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Rats; Regional Blood Flow; Theophylline | 1987 |
Additive renal effects of indomethacin and dipyridamole in man.
Topics: Adenosine; Adolescent; Adult; Body Water; Dipyridamole; Diuresis; Drug Interactions; Female; Glomerular Filtration Rate; Humans; Indomethacin; Kidney; Kidney Diseases; Male; Middle Aged; Natriuresis; p-Aminohippuric Acid; Prostaglandins; Theophylline | 1987 |
Effects of N6-(L-phenylisopropyl)adenosine, caffeine, theophylline and rolipram on the acquisition of conditioned responses in the rabbit.
Topics: Adenosine; Animals; Caffeine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Rolipram; Theophylline | 1987 |
Electrophysiological effects of adenosine and dipyridamole on cardiac Purkinje fibers and ventricular myocardium.
Topics: Action Potentials; Adenosine; Animals; Calcium; Dipyridamole; Dogs; Guinea Pigs; Heart; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Isoproterenol; Propranolol; Purkinje Fibers; Theophylline; Ventricular Function | 1987 |
Adenosine inhibits exocytotic release of endogenous noradrenaline in rat heart: a protective mechanism in early myocardial ischemia.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Coronary Circulation; Coronary Disease; Disease Models, Animal; Electric Stimulation; Exocytosis; Heart; Male; Myocardium; Norepinephrine; Phenylisopropyladenosine; Rats; Theophylline | 1987 |
An antiadrenergic effect of adenosine on guinea-pig but not rabbit ventricles.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Papillary Muscles; Phenylisopropyladenosine; Rabbits; Species Specificity; Sympatholytics; Theophylline | 1987 |
Possible role of adenosine in the relaxant effect of amrinone on guinea-pig ileum.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Amrinone; Animals; Dipyridamole; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Relaxants, Central; Muscle, Smooth; Rats; Theophylline | 1987 |
Effects of dipyridamole and theophylline on reactive hyperaemia in subcutaneous adipose tissue in humans.
Topics: Adenosine; Adipose Tissue; Adult; Blood Pressure; Dipyridamole; Female; Humans; Male; Regional Blood Flow; Theophylline | 1987 |
Lipolysis in diabetic adipocytes: differences in response to growth hormone and adenosine.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Epinephrine; Growth Hormone; Lipolysis; Male; Rats; Theophylline | 1987 |
Effects of adenosine and theophylline on canine tracheal smooth muscle tone.
Topics: Adenine; Adenosine; Animals; Dipyridamole; Dogs; Drug Interactions; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Theophylline; Trachea | 1987 |
Transient increase in release of adenosine during rapid cardiac pacing; transient effects on overdrive suppression of ventricular automaticity.
Topics: Adenine; Adenosine; Animals; Cardiac Pacing, Artificial; Electrocardiography; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1987 |
Suppression of human polymorphonuclear leukocyte phagocytosis by adenosine analogs.
Topics: Adenosine; Dipyridamole; Dose-Response Relationship, Drug; Humans; Latex; Leukocytes; Phagocytosis; Theophylline | 1987 |
Theophylline-induced upregulation of A1-adenosine receptors associated with reduced sensitivity to convulsants.
Topics: Adenosine; Animals; Convulsants; Drug Tolerance; Kinetics; Male; Mathematics; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1987 |
Pertussis toxin reduces the antiadrenergic effect of 2-chloroadenosine on papillary muscle and the direct negative inotropic effect of 2-chloroadenosine on atrium.
Topics: 2-Chloroadenosine; Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxants, Central; Myocardial Contraction; Papillary Muscles; Pertussis Toxin; Sympatholytics; Theophylline; Virulence Factors, Bordetella | 1987 |
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration | 1987 |
Electrophysiological evidence for adenosine receptors on astrocytes of cultured rat central nervous system.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Astrocytes; Cells, Cultured; Cerebellum; Membrane Potentials; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Spinal Cord; Theophylline | 1987 |
The role of myogenic relaxation, adenosine and prostaglandins in human forearm reactive hyperaemia.
Topics: Adenosine; Adult; Arteries; Constriction; Female; Forearm; Humans; Ibuprofen; Male; Muscle Contraction; Muscle Relaxation; Prostaglandins; Regional Blood Flow; Theophylline; Veins | 1987 |
Does endogenous adenosine modulate the release of acetylcholine from motor nerve during single and repetitive stimulations in the mouse diaphragm?
Topics: Acetylcholine; Adenosine; Animals; Dipyridamole; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred ICR; Motor Endplate; Motor Neurons; Muscle Contraction; Theophylline | 1987 |
Biochemical characterization of the antagonist actions of the xanthines, PACPX (1,3-dipropyl-8(2-amino-4-chloro)phenylxanthine) and 8-PT (8-phenyltheophylline) at adenosine A1 and A2 receptors in rat brain tissue.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; In Vitro Techniques; Kinetics; Rats; Receptors, Purinergic; Theophylline; Xanthines | 1987 |
Comparative effects of theophylline and adenosine on respiratory skeletal and smooth muscle.
Topics: Adenosine; Animals; Diaphragm; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Muscles; Respiration; Theophylline; Trachea | 1986 |
Interaction of amrinone with endogenous adenosine in guinea-pig atria.
Topics: Adenosine; Adenosine Deaminase; Aminopyridines; Amrinone; Animals; Cardiac Glycosides; Cardiotonic Agents; Dipyridamole; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Reserpine; Theophylline | 1986 |
Effect of the adenosine antagonist 8-phenyltheophylline on glycerol-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenosine; Animals; Creatinine; Glycerol; Heart Rate; Inulin; Kidney; Male; Organ Size; Rats; Rats, Inbred Strains; Theophylline; Urea | 1986 |
Actions and interactions of adenosine, theophylline and enprofylline on the guinea-pig spirally cut trachea.
Topics: Adenosine; Animals; Bronchodilator Agents; Carbachol; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Theophylline; Trachea; Xanthines | 1986 |
Effect of theophylline on the initiation phase of postischemic acute renal failure in rats.
Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Body Weight; Glomerular Filtration Rate; Inulin; Male; Potassium; Rats; Rats, Inbred Strains; Renal Artery Obstruction; Renal Circulation; Sodium; Theophylline | 1986 |
Adenosine analogues. The temperature-dependence of the anticonvulsant effect and inhibition of 3H-D-aspartate release.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Aspartic Acid; Body Temperature; Dose-Response Relationship, Drug; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; Motor Activity; Potassium; Rats; Rats, Inbred Strains; Theophylline; Tritium | 1986 |
Suppression by 5'-methylthioadenosine of histamine or leukotriene-induced contraction in isolated guinea pig tracheal rings.
Topics: Adenosine; Animals; Deoxyadenosines; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Propranolol; Receptors, Purinergic; SRS-A; Tetrodotoxin; Theophylline; Thionucleosides | 1986 |
Reduction of liver plasma flow by caffeine and theophylline.
Topics: Adenosine; Adult; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Humans; Indocyanine Green; Kinetics; Liver Circulation; Male; Middle Aged; Norepinephrine; Theophylline | 1986 |
Nucleoside transporter of cerebral microvessels and choroid plexus.
Topics: Adenosine; Affinity Labels; Animals; Blood Proteins; Blood-Brain Barrier; Brain; Capillaries; Choroid Plexus; Dipyridamole; Endothelium; Female; Guanosine; Male; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Rats; Rats, Inbred Strains; Swine; Theophylline; Thioinosine; Thionucleosides | 1986 |
Effect of adenosine on atrioventricular conduction. II: Modulation of atrioventricular node transmission by adenosine in hypoxic isolated guinea pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Atrioventricular Node; Depression, Chemical; Guinea Pigs; Heart Block; Heart Conduction System; Oxygen; Perfusion; Receptors, Purinergic; Theophylline; Time Factors | 1986 |
Possible role for adenosine in local regulation of absorptive hyperemia in rat intestine.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Dose-Response Relationship, Drug; Intestinal Absorption; Jejunum; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline | 1986 |
Autoregulation of superior mesenteric artery is blocked by adenosine antagonism.
Topics: Adenosine; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Homeostasis; Isoproterenol; Male; Mesenteric Arteries; Theophylline; Vascular Resistance; Vasodilator Agents | 1986 |
Effect of theophylline on ischemically induced hippocampal damage in Mongolian gerbils: a behavioral and histopathological study.
Topics: Adenosine; Animals; Behavior, Animal; Brain Ischemia; Cerebrovascular Circulation; Gerbillinae; Hippocampus; Male; Necrosis; Receptors, Purinergic; Theophylline | 1987 |
Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-sulfophenyl)theophylline.
Topics: Adenosine; Blood Pressure; Brain; Caffeine; Heart Rate; Hemodynamics; Receptors, Purinergic; Theophylline | 1987 |
Two saturable recognition sites for (-) [125I]iodo-N6-(4-hydroxyphenyl-isopropyl)-adenosine binding on purified cardiac sarcolemma.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Cattle; Guinea Pigs; Iodine Radioisotopes; Myocardium; Phenylisopropyladenosine; Receptors, Purinergic; Sarcolemma; Theophylline | 1986 |
Characterization of the antinociceptive effects of some adenosine analogues in the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Dose-Response Relationship, Drug; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline; Xanthines | 1986 |
Purinoceptors in the rat heart.
Topics: 6-Ketoprostaglandin F1 alpha; Adenine Nucleotides; Adenosine; Animals; Chromatography, Thin Layer; Coronary Circulation; Coronary Vessels; Male; Myocardial Contraction; Perfusion; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Vasodilation | 1987 |
Effect of theophylline treatment on the functional hyperaemic and hypoxic responses of cerebrocortical microcirculation.
Topics: Adenosine; Animals; Cats; Cerebral Cortex; Cerebrovascular Circulation; Extracellular Space; Hyperemia; Hypoxia; Male; Microcirculation; NAD; Theophylline | 1986 |
An in vitro analysis of purine-mediated renal vasoconstriction in rat isolated kidney.
Topics: 2-Chloroadenosine; Adenosine; Animals; Colforsin; Male; Methoxamine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1987 |
Regulation of cerebral blood flow (CBF) during hypoxia and epileptic seizures.
Topics: 2-Chloroadenosine; Adenosine; Amobarbital; Animals; Cats; Cerebrovascular Circulation; Cyanides; Epilepsy; Hypoxia; Theophylline | 1985 |
Characterization of adenosine-induced respiratory depression in the preterm rabbit.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Apnea; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylisopropyladenosine; Rabbits; Respiration Disorders; Theophylline; Tidal Volume; Time Factors | 1985 |
Dipyridamole decreases glomerular filtration in the sodium-depleted dog. Evidence for mediation by intrarenal adenosine.
Topics: Adenosine; Animals; Dipyridamole; Dogs; Female; Glomerular Filtration Rate; Kidney; Male; Radioisotope Dilution Technique; Sodium; Theophylline | 1985 |
Effect of calcium entry blockers and adenosine on the relaxation of large and small coronary arteries.
Topics: Adenosine; Animals; Arteries; Calcium Channel Blockers; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Gallopamil; Lidoflazine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Theophylline | 1986 |
Role of adenosine in hyperemic response of coronary blood flow in microembolization.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Embolism; Hemodynamics; Hyperemia; Injections; Microspheres; Particle Size; Theophylline | 1986 |
Evidence that the intracellular effects of adenosine in the guinea-pig aorta are mediated by inosine.
Topics: Adenosine; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Inosine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Theophylline; Thioinosine | 1986 |
Calcium entry blocking activity of dilazep and other adenosine potentiating compounds in guinea-pig atria.
Topics: Adenosine; Adenosine Deaminase; Animals; Azepines; Calcium; Calcium Channel Blockers; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Atria; Isoproterenol; Lidoflazine; Myocardial Contraction; Theophylline | 1986 |
The effects of adenosine, ATP and ADP on ventricular automaticity induced by a local injury in the isolated right ventricle of the rat.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Female; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Theophylline; Ventricular Function | 1986 |
Inhibitory effect of quinacrine on myocardial reactive hyperemia in the dog.
Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Catechols; Coronary Circulation; Dogs; Female; Heart Rate; Hyperemia; Indomethacin; Male; Masoprocol; Pyrazoles; Quinacrine; Regional Blood Flow; Theophylline; Verapamil | 1985 |
Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation.
Topics: Adenosine; Aequorin; Animals; Body Fluids; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Ferrets; In Vitro Techniques; Intracellular Fluid; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Portal Vein; Potassium; Theophylline | 1985 |
Electrical responses of smooth muscle cells of the rabbit ear artery to adenosine triphosphate.
Topics: Action Potentials; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cocaine; Dose-Response Relationship, Drug; Ear, External; Female; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Phentolamine; Quinidine; Rabbits; Theophylline | 1985 |
Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes.
Topics: 2-Chloroadenosine; Adenosine; Cytochalasin B; Free Radicals; Humans; Latex; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Theophylline | 1985 |
A possible explanation for a greater discrepant suppression by adenosine and N6-cyclohexyl adenosine of the guinea-pig ileal contraction.
Topics: Adenosine; Animals; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purines; Theophylline | 1985 |
Adenosine antagonists. Lack of effect on the inhibition of kindled seizures in rats by carbamazepine.
Topics: Adenosine; Animals; Caffeine; Carbamazepine; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Seizures; Theophylline | 1985 |
The use of 8-phenyltheophylline as a competitive antagonist of adenosine and an inhibitor of the intrinsic regulatory mechanism of the hepatic artery.
Topics: Adenosine; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Hepatic Artery; Male; Regional Blood Flow; Theophylline; Vasodilation | 1985 |
Potent depressant effects of adenosine analogs on hippocampal slow-wave activity in the unanesthetized rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Depression, Chemical; Electroencephalography; Hippocampus; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Stereoisomerism; Theophylline | 1985 |
Adenosine-induced secretion in the canine trachea: modification by methylxanthines and adenosine derivatives.
Topics: Adenosine; Animals; Dogs; In Vitro Techniques; Mucous Membrane; Mucus; Stimulation, Chemical; Theophylline; Trachea; Xanthines | 1985 |
Antagonism by theophylline of respiratory inhibition induced by adenosine.
Topics: Adenosine; Animals; Cats; Injections, Intravenous; Injections, Intraventricular; Phenylisopropyladenosine; Phrenic Nerve; Respiration; Theophylline | 1985 |
Adenosine potentiates secretin-stimulated pancreatic exocrine secretion in the dog.
Topics: Adenosine; Animals; Blood Pressure; Dogs; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Electrolytes; Female; Male; Pancreas; Pancreatic Juice; Secretin; Theophylline | 1985 |
Possibilities for adenosine modulation of peristaltic reflex in guinea pig isolated ileum.
Topics: Adenosine; Animals; Atropine; Autoradiography; Dipyridamole; Gastrointestinal Motility; Guinea Pigs; Histocytochemistry; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Peristalsis; Quinacrine; Reflex; Tetrodotoxin; Theophylline | 1985 |
Dissociation of catecholamine-induced formation of adenosine 3'5'-monophosphate and release of glycerol in fat cells by prostaglandin E1, E2 and N6-phenylisopropyladenosine.
Topics: Adenosine; Adenylyl Cyclases; Adipose Tissue; Adrenergic beta-Antagonists; Animals; Butylamines; Catecholamines; Cyclic AMP; Dose-Response Relationship, Drug; Glycerol; Hormones; In Vitro Techniques; Kinetics; Norepinephrine; Phenyl Ethers; Propanolamines; Propylamines; Prostaglandins; Stimulation, Chemical; Theophylline; Time Factors; Tritium | 1974 |
Repression of alkaline phosphatase synthesis by adenine, adenosine and adenine nucleotides in an adenine auxotroph of Bacillus anthracis.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Alkaline Phosphatase; Bacillus anthracis; Caffeine; Chlorpromazine; Culture Media; Dinitrophenols; Enzyme Repression; Inosine Nucleotides; Lyases; Mutation; Phosphates; Theophylline | 1973 |
The influence on platelet aggregation of drugs that affect the accumulation of adenosine 3':5'-cyclic monophosphate in platelets.
Topics: Adenine Nucleotides; Adenosine; Blood Platelets; Carbon Isotopes; Cyclic AMP; Dipyridamole; Humans; In Vitro Techniques; Isoproterenol; Papaverine; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Prostaglandins; Theophylline | 1971 |
Formation and metabolism of cyclic AMP in the mammalian central nervous system.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Mice; Norepinephrine; Potassium; Rabbits; Rats; Theophylline | 1971 |
The mode of action of dibutyryl adenosine 3',5'-monophosphate on bone tissue in vitro.
Topics: Adenosine; Adenosine Monophosphate; Animals; Animals, Newborn; Body Fluids; Bone and Bones; Butyrates; Cattle; Chromatography, Ion Exchange; Cyclic AMP; Depression, Chemical; Female; Glucose; In Vitro Techniques; Inulin; Metabolism; Nucleotides; Phosphoric Monoester Hydrolases; Pregnancy; Rats; Serum Albumin, Bovine; Skull; Stimulation, Chemical; Theophylline; Time Factors; Tritium | 1971 |
Factors influencing the accumulation of cyclic AMP in brain tissue.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Brain; Cerebellum; Cerebral Cortex; Cyclic AMP; Diphenhydramine; Dogs; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Magnesium; Mice; Norepinephrine; Osmolar Concentration; Phosphorus Isotopes; Potassium; Potassium Chloride; Rats; Serotonin; Theophylline; Tissue Extracts; Tritium | 1970 |
The determination of nikethamide and other compounds in pharmaceutical dosage forms by thin-layer chromatography.
Topics: Adenosine; Caffeine; Chromatography, Thin Layer; Dosage Forms; Gels; Methods; Niacinamide; Silicon Dioxide; Solvents; Spectrophotometry; Strychnine; Theophylline; Ultraviolet Rays | 1971 |
Permeation of dibutyryl cAMP into HeLa cells and its convesion to monobutyryl cAMP.
Topics: Adenosine; Adenosine Monophosphate; Biological Transport; Butyrates; Cyclic AMP; HeLa Cells; Phosphotransferases; Protein Binding; Proteins; Purine Nucleotides; Theophylline; Tritium | 1972 |
Effect of phenylisopropyladenosine ((Th 162) on lipolysis in human adipose tissue slices.
Topics: Adenosine; Adipose Tissue; Butyrates; Cyclic AMP; Depression, Chemical; Drug Antagonism; Glycerol; Humans; Hypolipidemic Agents; In Vitro Techniques; Lipid Mobilization; Norepinephrine; Propylamines; Theophylline | 1970 |
Stimulation of release of adrenal catecholamine by adenosine 3':5'-cyclic monophosphate and theophylline in the absence of extracellular Ca 2+ .
Topics: Adenosine; Adenosine Monophosphate; Adrenal Glands; Animals; Butyrates; Calcium; Catecholamines; Cats; Cyclic AMP; Drug Synergism; Female; In Vitro Techniques; Male; Nicotine; Perfusion; Potassium Chloride; Stimulation, Chemical; Theophylline; Time Factors; Xanthines | 1972 |
Effect of depolarizing agents on accumulation of cyclic adenosine 3',5'-monophosphate in cerebral cortical slices.
Topics: Adenosine; Alkaloids; Animals; Brain Chemistry; Carbon Isotopes; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Ouabain; Phosphoric Diester Hydrolases; Potassium; Pregnanes; Pyrroles; Quaternary Ammonium Compounds; Rabbits; Tetrodotoxin; Theophylline; Toxins, Biological; Veratrine | 1972 |
Inhibition of platelet aggregation by chemicals and drugs.
Topics: Adenosine; Amitriptyline; Blood Coagulation; Blood Platelets; Chlorpromazine; Cyclic AMP; Fibrinogen; Imipramine; Prostaglandins; Theophylline | 1971 |
The effects of propranolol and electrical stimulation on the cyclic 3',5'-AMP content of isolated cerebral tissue.
Topics: Adenosine; Animals; Carbon Isotopes; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Guinea Pigs; Procaine; Propranolol; Theophylline; Tritium | 1972 |
The effect of adenosine on the release of the transmitter from the phrenic nerve of the rat.
Topics: Adenosine; Animals; Calcium; Cyclic AMP; Diaphragm; Electric Stimulation; Electrophysiology; In Vitro Techniques; Magnesium; Male; Neuromuscular Junction; Phrenic Nerve; Rats; Synaptic Transmission; Theophylline; Tubocurarine | 1972 |
Effects of adenosine nucleosides on adenylate cyclase, phosphodiesterase, cyclic adenosine monophosphate accumulation, and lipolysis in fat cells.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Arabinose; Cell Membrane; Cyclic AMP; Deoxyadenosines; Enzyme Activation; Feedback; Female; Fluorine; Lipid Mobilization; Norepinephrine; Nucleosides; Phosphodiesterase Inhibitors; Rats; Theophylline; Tritium | 1972 |
Adenylate cyclase, phosphodiesterases and protein kinase of rat glial cells in culture.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Biogenic Amines; Cyclic AMP; Enzyme Activation; Histones; Isoproterenol; Kinetics; Neuroglia; Phenoxybenzamine; Phosphoric Diester Hydrolases; Phosphorus Isotopes; Phosphotransferases; Propranolol; Rats; Subcellular Fractions; Temperature; Theophylline; Tritium | 1972 |
The formation and distribution of cyclic 3',5'-adenosine monophosphate in the everted guinea pig seminal vesicle sac.
Topics: Adenosine; Animals; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Male; Seminal Vesicles; Testosterone; Theophylline; Tritium | 1973 |
The effect of cyclic adenosine- and guanosine 3',5'-monophosphate on the normal and drug-increased coronary blood flow.
Topics: Adenosine; Animals; Aorta; Benzyl Compounds; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Cyclic AMP; Cyclic GMP; Dogs; Epinephrine; Lipid Metabolism; Muscle, Smooth; Theophylline; Vasodilator Agents | 1972 |
Characterization of two forms of beef heart cyclic nucleotide phosphodiesterase.
Topics: Adenosine; Aminohydrolases; Ammonium Sulfate; Animals; Cattle; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Electrophoresis, Disc; Kinetics; Molecular Weight; Myocardium; Nucleotidases; Nucleotides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Theophylline; Tritium; Ultracentrifugation | 1972 |
Cyclic AMP and citric acid accumulation by Aspergillus niger.
Topics: Adenine Nucleotides; Adenosine; Aspergillus; Citrates; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Sucrose; Theophylline; Time Factors | 1973 |
Regulation of cyclic AMP metabolism in cultured cells of the nervous system.
Topics: Adenosine; Aminobutyrates; Animals; Brain; Carbachol; Catecholamines; Cell Division; Cells, Cultured; Cyclic AMP; Dopamine; Fetus; Histamine; Isoproterenol; Mice; Neuroblastoma; Neuroglia; Neurons; Phentolamine; Prostaglandins; Rats; Serotonin; Sotalol; Theophylline; Time Factors | 1972 |
Regulation of levels of guanosine cyclic 3',5'-monophosphate in the central nervous system: effects of depolarizing agents.
Topics: Adenosine; Animals; Central Nervous System; Cerebellum; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; Mice; Mice, Inbred Strains; Neuromuscular Depolarizing Agents; Ouabain; Potassium; Synaptic Transmission; Theophylline; Time Factors; Veratrine | 1973 |
Studies on the antilipolytic effect of adenosine and related compounds in isolated fat cells.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Culture Techniques; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Glycerol; Hypoxanthines; Inosine; Insulin; Male; Norepinephrine; Rats; Theophylline; Xanthines | 1973 |
Cyclic AMP and cyclic GMP enhance growth of chick embryo fibroblasts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bucladesine; Cell Division; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Fibroblasts; Inosine Nucleotides; Kinetics; Nucleotides, Cyclic; Theophylline; Tritium; Xanthines | 1973 |
Stimulation of ornithine decarboxylase and nuclear RNA polymerase activity in rat liver by glucagon and dibutyryl cyclic amp.
Topics: Adenosine; Adrenalectomy; Animals; Bucladesine; Carbon Radioisotopes; Carboxy-Lyases; Cycloheximide; Dactinomycin; Depression, Chemical; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Female; Glucagon; Liver; Mycotoxins; Nucleotides; Ornithine; Rats; Stimulation, Chemical; Theophylline; Time Factors | 1973 |
Divergent action mechanism of cAMP and dibutyryl cAMP on cell proliferation and macromolecular synthesis in HeLa S3 cultures.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Bucladesine; Butyrates; Cell Division; Cyclic AMP; DNA, Neoplasm; Glycogen; HeLa Cells; Kinetics; Phosphodiesterase Inhibitors; RNA, Neoplasm; Theophylline; Thymidine; Tritium; Uracil Nucleotides; Uridine | 1973 |
The lysosomal system in lymphocytes--from cyclic AMP to gene activation.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bucladesine; Carbon Radioisotopes; Cell Nucleus; Cyclic AMP; DNA-Directed RNA Polymerases; Genes; Humans; Hydrolases; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Lysosomes; Templates, Genetic; Theophylline; Trypsin | 1971 |
Promotion of conidia aggregation in Aspergillus niger by cyclic AMP and 5'-GMP.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aspergillus; Bucladesine; Cell Aggregation; Cell Division; Cyclic AMP; Cyclic GMP; Guanine Nucleotides; Guanosine; Theophylline | 1973 |
Effect of dibutyryl cyclic AMP on the induction of Epstein-Barr virus in hybrid cells.
Topics: Adenosine; Adenosine Monophosphate; Antigens, Viral; Bucladesine; Butyrates; Culture Media; Cyclic AMP; Fluorescent Antibody Technique; Herpesvirus 4, Human; Hybrid Cells; Idoxuridine; Theophylline | 1973 |
Cyclic nucleotides as intracellular mediators of the expression of antigen-sensitive cells.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antibody Formation; Antibody-Producing Cells; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic GMP; Depression, Chemical; Erythrocytes; Hemolytic Plaque Technique; Immunity, Cellular; Kinetics; Mice; Papaverine; Sheep; Spleen; Theophylline | 1973 |
Cyclic 3',5'-adenosine monophosphate in isolated bone cells. II. Responses to adenosine and parathyroid hormone.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bone and Bones; Carbon Radioisotopes; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Fluorides; Guanosine; In Vitro Techniques; Parathyroid Hormone; Rats; Theophylline; Uridine | 1974 |
Effects of cyclic 3',5'-AMP and related compounds on catecholamine-induced contraction of isolated guinea-pig vas deferens.
Topics: Acetylcholine; Adenosine; Animals; Catecholamines; Cyclic AMP; Drug Synergism; Epinephrine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Receptors, Adrenergic; Theophylline; Vas Deferens | 1973 |
Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.
Topics: Adenosine; Animals; Atropine; Benzyl Compounds; Bethanechol Compounds; Calcium; Carbachol; Cyclic AMP; Electric Stimulation; Ethers; Ganglia, Spinal; Hexamethonium Compounds; Imidazoles; In Vitro Techniques; Moxisylyte; Parasympatholytics; Phenoxybenzamine; Phentolamine; Phosphodiesterase Inhibitors; Rabbits; Sotalol; Sympatholytics; Synapses; Theophylline; Time Factors | 1974 |
Inhibition of platelet aggregation by isochinoline derivatives.
Topics: Adenosine; Adenosine Diphosphate; Blood Coagulation; Blood Platelets; Calcium; Collagen; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Glucose; Humans; In Vitro Techniques; Isoproterenol; Isoquinolines; Papaverine; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Prostaglandins; Theophylline; Time Factors | 1972 |
Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase.
Topics: Adenine; Adenosine; Aminohydrolases; Animals; Carbon Radioisotopes; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Norepinephrine; Ouabain; Potassium; Theophylline; Veratrine | 1973 |
Adenosine-mediated elevation of cyclic 3':5'-adenosine monophosphate concentrations in cultured mouse neuroblastoma cells.
Topics: Acetylcholine; Adenine; Adenosine; Animals; Benzyl Compounds; Clone Cells; Cyclic AMP; Ethers; Guanine; Guanosine; Histamine; Imidazoles; Isoproterenol; Mice; Neuroblastoma; Phosphodiesterase Inhibitors; Stimulation, Chemical; Theophylline | 1973 |
Investigation of the release reaction in platelets exposed to phorbol myristate acetate.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alcohols; Blood Platelets; Carbon Radioisotopes; Cytoplasmic Granules; Diterpenes; Edetic Acid; Epinephrine; Fatty Acids; Glycogen; Histocytochemistry; Humans; L-Lactate Dehydrogenase; Microscopy, Electron; Microtubules; Mitochondria; Organoids; Phosphoric Monoester Hydrolases; Platelet Adhesiveness; Prostaglandins; Pyruvate Kinase; Serotonin; Theophylline | 1974 |
Inhibition of adenosine cyclic 3', 5'-monophosphate accumulation in fat cells by adenosine, N6-(phenylisopropyl) adenosine, and related compounds.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adipose Tissue; Aminohydrolases; Animals; Cells, Cultured; Cyclic AMP; Dipyridamole; Female; Microbial Collagenase; Norepinephrine; Papaverine; Phosphodiesterase Inhibitors; Puromycin; Rats; Theophylline; Time Factors; Xanthines | 1973 |
Adenosine-elicited accumulation of cyclic AMP in brain slices: potentiation by agents which inhibit uptake of adenosine.
Topics: Adenosine; Animals; Benzoates; Biological Transport; Bucladesine; Carbon Radioisotopes; Cerebral Cortex; Cyclic AMP; Deoxyadenosines; Dipyridamole; Drug Synergism; Ethylenediamines; Guanosine; Guinea Pigs; Histamine; Male; Norepinephrine; Papaverine; Purine Nucleosides; Structure-Activity Relationship; Theophylline; Xanthines | 1974 |
N6-substituted adenines induce cell elongation irrespective of the intracellular cyclic AMP levels.
Topics: Adenine; Adenosine; Animals; Cell Adhesion; Cell Movement; Cell-Free System; Cells, Cultured; Cyclic AMP; Fibroblasts; L Cells; Mice; Microscopy, Phase-Contrast; Phosphoric Diester Hydrolases; Purines; Theophylline; Tritium; Xanthines | 1974 |
Stimulation of cyclic adenosine 3',5'-monophosphate accumulation and lipolysis in fat cells by adenosine deaminase.
Topics: Adenosine; Adipose Tissue; Aminohydrolases; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Glycerol; In Vitro Techniques; Insulin; Lipid Metabolism; Male; Nicotinic Acids; Norepinephrine; Stimulation, Chemical; Theophylline; Time Factors | 1974 |
Cyclic adenosine 3':5'-monophosphate metabolism in normal and SV40-transformed WI-38 cells.
Topics: 1-Propanol; Adenosine; Adenylyl Cyclases; Adrenocorticotropic Hormone; Cell Line; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Cyclic AMP; Epinephrine; Fluorides; Glucagon; Histamine; Humans; Insulin; Kinetics; Lung; Norepinephrine; Prostaglandins; Simian virus 40; Theophylline; Time Factors | 1974 |
Facilitation by adenosine of the action of insulin on the accumulation of adenosine 3':5'-monophosphate, lipolysis, and glucose oxidation in isolated fat cells.
Topics: Adenosine; Adenosine Triphosphate; Adipose Tissue; Aminohydrolases; Animals; Cyclic AMP; Dipyridamole; Glucose; Insulin; Insulin Antagonists; Lipid Metabolism; Male; Norepinephrine; Oxidation-Reduction; Phosphoric Diester Hydrolases; Rats; Theophylline | 1974 |
Regulation of adenosine 3':5'-monophosphate content in human astrocytoma cells by adenosine and the adenine nucleotides.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Astrocytoma; Biological Transport; Carbon Radioisotopes; Cell Line; Chromatography, Ion Exchange; Chromatography, Paper; Clone Cells; Cyclic AMP; Humans; Kinetics; Norepinephrine; Papaverine; Phentolamine; Phosphoric Diester Hydrolases; Propranolol; Receptors, Drug; Theophylline; Time Factors; Tritium; Xanthines | 1974 |
c-AMP phosphodiesterase activity during growth and differentiation in Blastocladiella emersonii.
Topics: Adenosine; Adenosine Monophosphate; Calcium; Cell Differentiation; Culture Media; Cyclic AMP; Enzyme Activation; Fungi; Lithium; Magnesium; Phosphoric Diester Hydrolases; Potassium; Spores, Fungal; Theophylline; Tritium | 1974 |
Immunological phagocytosis: effect of drugs on phosphodiesterase activity.
Topics: Adenosine; Adenosine Monophosphate; Animals; Cyclic AMP; Depression, Chemical; Erythrocytes; Female; Imidazoles; In Vitro Techniques; Macrophages; Mice; Phagocytosis; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Sheep; Stimulation, Chemical; Theophylline; Thiazoles | 1974 |
Stimulated formation of cyclic adenosine 3':5'-monophosphate by aspartate and glutamate in cerebral cortical slices of guinea pig.
Topics: Adenine; Adenosine; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cocaine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Guinea Pigs; Kinetics; Male; Phosphoric Diester Hydrolases; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship; Theophylline | 1974 |
The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines.
Topics: Adenine; Adenosine; Animals; Bucladesine; Caffeine; Cell Aggregation; Colchicine; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Leukocytes; Nucleotides, Cyclic; Rabbits; Stimulation, Chemical; Theobromine; Theophylline; Vinblastine; Xanthines | 1974 |
Studies on lipolysis in lipid micelles isolated from adipose tissue.
Topics: Adenosine; Adenosine Monophosphate; Adipose Tissue; Animals; Bucladesine; Caffeine; Colloids; Cyclic AMP; Epididymis; Epinephrine; In Vitro Techniques; Lipid Metabolism; Macromolecular Substances; Male; Phospholipases; Rats; Theophylline | 1974 |
Rabbit testicular capsular contractions--prostaglandins, cyclic adenosine 3',5'-monophosphate and epinephrine.
Topics: Adenosine; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Ergotamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Tonus; Propranolol; Prostaglandins; Rabbits; Testis; Theophylline | 1974 |
Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig and rat.
Topics: Adenosine; Animals; Benzyl Compounds; Cerebral Cortex; Chlordiazepoxide; Cyclic AMP; Diazepam; Ethers; Guinea Pigs; Histamine; Hydrazines; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Oxazepam; Phosphodiesterase Inhibitors; Pyrazoles; Pyridines; Rats; Species Specificity; Theophylline | 1974 |
Role of cyclic adenosine 3':5'-monophosphate in the action of 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT)on hepatic and renal metabolism.
Topics: Adenosine; Adenylyl Cyclases; Animals; Blood Glucose; Carboxy-Lyases; Cyclic AMP; DDT; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Glycosuria; Kidney; Liver; Male; Models, Biological; Phosphoenolpyruvate; Phosphoric Diester Hydrolases; Pyruvate Carboxylase; Rats; Theophylline; Tritium | 1974 |
Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion.
Topics: Adenosine; Anti-Bacterial Agents; Aspirin; Atropine; Blood Platelets; Bucladesine; Calcium; Carbon Radioisotopes; Carboxylic Acids; Cyclic AMP; Cytoplasm; Deoxyglucose; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Ethylmaleimide; Humans; L-Lactate Dehydrogenase; Lanthanum; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Serotonin; Theophylline | 1974 |
Structure-activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart.
Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Heart Atria; Histamine; Histidine; Hydrogen-Ion Concentration; Hypoxanthines; Imidazoles; In Vitro Techniques; Naphazoline; Phentolamine; Pilocarpine; Potassium; Pyridines; Rana pipiens; Solutions; Structure-Activity Relationship; Surface Tension; Theobromine; Theophylline; Tolazoline; Xanthines | 1974 |
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Cyclic AMP; Hypoxanthines; In Vitro Techniques; Inosine; Isoproterenol; Muscle Contraction; Muscles; Nucleosides; Phenytoin; Propranolol; Protein Binding; Purines; Rana pipiens; Ribose; Sorbitol; Theophylline; Tritium; Uridine | 1974 |
Cyclic AMP-induced tyrosinase synthesis in Neurospora crassa.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Bucladesine; Caffeine; Catechol Oxidase; Cyclic AMP; Cycloheximide; Enzyme Induction; Neurospora; Neurospora crassa; Theophylline | 1974 |
Adenosine cyclic 3',5'-monophosphate in fetal rat brain cell cultures. I. Effect of catecholamines.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Brain; Brain Chemistry; Catecholamines; Cells, Cultured; Cyclic AMP; Dopamine; Gestational Age; Histamine; Isoproterenol; Norepinephrine; Potassium Chloride; Prostaglandins; Rats; Rats, Inbred Strains; Serotonin; Theophylline | 1972 |
Cyclic adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices. II. The role of phosphodiesterase activity in the regulation of levels of cyclic adenosine 3',5'-monophosphate.
Topics: Adenosine; Animals; Biogenic Amines; Butyrates; Carbon Isotopes; Cerebral Cortex; Cyclic AMP; Drug Synergism; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Norepinephrine; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Quaternary Ammonium Compounds; Theophylline; Tritium; Veratrine; Xanthines | 1973 |
[The effect of methylxanthines on catecholamine and adenylate nucleotide concentration in rat myocardium].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Caffeine; Inosine; Inosine Nucleotides; Myocardium; Phosphorus; Rats; Stimulation, Chemical; Strophanthins; Theobromine; Theophylline; Tyramine; Xanthines | 1974 |
The effect of carbocromen and dipyridamole on blood flow of the gastrocnemius of the dog.
Topics: Acetylcholine; Adenosine; Aminophylline; Animals; Blood Pressure; Coumarins; Diethylamines; Dipyridamole; Dogs; Electric Stimulation; Female; Glycolates; Injections, Intra-Arterial; Injections, Intravenous; Isoproterenol; Male; Muscles; Papaverine; Regional Blood Flow; Theophylline; Vasodilator Agents | 1974 |
[Comparative investigation on the vitro inhibition of adenosine decomposition by dilazep].
Topics: Adenosine; Adult; Azepines; Benzoates; Caffeine; Cell Membrane Permeability; Dipyridamole; Drug Interactions; Erythrocytes; Ethylenediamines; Humans; In Vitro Techniques; Lidoflazine; Theophylline; Vasodilator Agents | 1974 |
On the mechanism of the antagonistic action of xanthine derivatives against adenosine and coronary vasodilators.
Topics: Acetamides; Adenosine; Animals; Blood Flow Velocity; Caffeine; Cell Membrane Permeability; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Drug Interactions; Erythrocytes; Female; Glycolates; Humans; Male; Piperazines; Receptors, Drug; Structure-Activity Relationship; Theophylline; Vasodilator Agents; Xanthines; Xylenes | 1972 |
[Effect of theophylline on the vascular resistance of cerebral vessels during normal and restricted circulation and adenosine perfusion].
Topics: Adenosine; Animals; Cerebrovascular Circulation; Dogs; Perfusion; Theophylline; Vascular Resistance; Venous Pressure | 1972 |
Theophylline and adenosine at the neuromuscular junction.
Topics: Adenosine; Animals; Diaphragm; Electrophysiology; In Vitro Techniques; Neuromuscular Junction; Rats; Theophylline | 1971 |
Endogenous adenosine as a modulator of hippocampal acetylcholine release.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Caudate Nucleus; Dipyridamole; Electric Stimulation; Hippocampus; In Vitro Techniques; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline | 1984 |
Adenosine inhibits and potentiates IgE-dependent histamine release from human basophils by an A2-receptor mediated mechanism.
Topics: Adenosine; Basophils; Cyclic AMP; Dipyridamole; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Receptors, Purinergic; Theophylline; Time Factors | 1983 |
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Antagonistic effect of theophylline on the adenosine-induced decreased in renin release.
Topics: Adenosine; Angiotensin II; Animals; Blood Pressure; Cyclic AMP; Dogs; Drug Interactions; Female; Glomerular Filtration Rate; Kidney; Kidney Cortex; Lymph; Male; Natriuresis; Regional Blood Flow; Renin; Theophylline | 1984 |
Theophylline-like properties of xanthine analogs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adult; Animals; Female; Humans; In Vitro Techniques; Male; Mice; Pyrazines; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Thymidine; Xanthines | 1984 |
Basal cyclic AMP levels in human blood mononuclear cells.
Topics: Adenosine; Adenosine Deaminase; Cyclic AMP; Humans; Indomethacin; Kinetics; Monocytes; Temperature; Theophylline | 1984 |
Ionic basis of the hyperpolarizing action of adenyl compounds on sinus venosus of the tortoise heart.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Animals; Biological Transport, Active; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Ion Channels; Ions; Myocardium; Potassium; Rubidium; Theophylline; Time Factors; Turtles | 1984 |
Adenosine analogs: potentiation of bradykinin-induced plasma exudation in rat skin and prevention by caffeine and theophylline.
Topics: Adenosine; Animals; Bradykinin; Caffeine; Capillary Permeability; Cyproheptadine; Drug Synergism; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Skin; Theophylline | 1984 |
Impaired hormonal regulation of lipolysis and the interference with adenosine in adipose tissue from hyperglycemic sand rats in vitro.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Arvicolinae; Cyclic AMP; Hyperglycemia; In Vitro Techniques; Insulin; Lipolysis; Norepinephrine; Phentolamine; Rodent Diseases; Theophylline | 1984 |
Regulation of human T lymphocyte surface antigen mobility by purinergic receptors.
Topics: Adenosine; Adult; Antigens, Surface; Cyclic AMP; Female; Humans; Immunologic Capping; Leukocyte Count; Male; Phosphodiesterase Inhibitors; Receptors, Antigen, T-Cell; Receptors, Cyclic AMP; Receptors, Neurotransmitter; Receptors, Purinergic; T-Lymphocytes; Theophylline | 1984 |
Adenosine: a modulator of gastric acid secretion in vivo.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Dogs; Gastric Acid; Histamine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Vasodilation | 1984 |
Adenosine receptor mediated inhibition of noradrenaline release from slices of the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Dipyridamole; Electric Stimulation; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline; Xanthines | 1984 |
Involvement of adenosine receptor activities in aggressive responses produced by clonidine in mice.
Topics: Adenosine; Aggression; Animals; Apomorphine; Bicuculline; Clonidine; Diazepam; Dipyridamole; Humans; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
The anticonvulsive action of adenosine: a postsynaptic, dendritic action by a possible endogenous anticonvulsant.
Topics: Adenosine; Animals; Anticonvulsants; Dendrites; Evoked Potentials; Hippocampus; In Vitro Techniques; Penicillins; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Effect of gamma-aminobutyric acid on cyclic nucleotides content of guinea-pig cerebral cortex slices.
Topics: Adenosine; alpha-Methyltyrosine; Animals; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Methyltyrosines; Neurons; Norepinephrine; Phentolamine; Picrotoxin; Reserpine; Theophylline | 1984 |
Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Line; Cells, Cultured; Cyclic AMP; Glioma; Humans; Kinetics; Neuroblastoma; Phenylisopropyladenosine; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Theophylline; Vasodilator Agents | 1984 |
Changes in noradrenaline release and in beta receptor number in rat hippocampus following long-term treatment with theophylline or L-phenylisopropyladenosine.
Topics: Adaptation, Physiological; Adenosine; Animals; Cell Membrane; Dihydroalprenolol; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Time Factors | 1984 |
[Receptors for lactoferrin on human thymic lymphocytes. The stimulation of expression as affected by adenosine, theophylline and a supernatant of thymic lymphocytes].
Topics: Adenosine; Adolescent; Animals; Child; Child, Preschool; Colostrum; Female; Fluorescent Antibody Technique; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Lactoferrin; Lactoglobulins; Levamisole; Rabbits; Receptors, Cell Surface; T-Lymphocytes; Theophylline; Thymus Extracts | 1984 |
Inhibitory effect of adenosine on transmission in sympathetic ganglia.
Topics: 2-Chloroadenosine; 4-Aminopyridine; Action Potentials; Adenosine; Aminopyridines; Animals; Dipyridamole; Electric Stimulation; Female; Ganglia, Sympathetic; In Vitro Techniques; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1984 |
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Rolipram; Synaptic Transmission; Tetrodotoxin; Theophylline | 1984 |
Effects of adenosine, adenosine triphosphate and structural analogues on glucagon secretion from the perfused pancreas of rat in vitro.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glucagon; In Vitro Techniques; Male; Nucleotidases; Pancreas; Rats; Theophylline | 1984 |
Neither vasoactive intestinal peptide (VIP) nor purine derivatives may mediate non-adrenergic tracheal inhibition.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Atropine; Carbachol; Electric Stimulation; Female; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Purines; Synaptic Transmission; Theophylline; Trachea; Vasoactive Intestinal Peptide | 1984 |
Adenosine mechanisms in the regulation of breathing in the rat.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug; Heart Rate; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Respiratory Function Tests; Stereoisomerism; Theophylline; Xanthines | 1984 |
Characterization of adenosine receptors in isolated cerebral arteries of cat.
Topics: Adenosine; Animals; Cats; Cerebral Arteries; Cyclic AMP; Female; In Vitro Techniques; Male; Receptors, Purinergic; Theophylline; Vasoconstriction; Xanthines | 1983 |
Presynaptic inhibition of neurotransmission in rat vas deferens by 2-(p-methoxyphenyl) adenosine, ethyl adenosine-5'-carboxylate and N-cyclopropyl adenosine-5'-carboxamide.
Topics: Adenosine; Animals; Dipyridamole; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Synaptic Transmission; Theophylline; Vas Deferens | 1980 |
Interactions between the benzodiazepines, methylxanthines, and adenosine.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Cerebral Cortex; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Theophylline | 1980 |
Studies on modulation of transmitter release and effector responsiveness in autonomic cholinergic neurotransmission.
Topics: Acetylcholine; Adenosine; Animals; Cattle; Cholinergic Fibers; Electric Stimulation; Female; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Prostaglandins; Receptors, Muscarinic; Synaptic Transmission; Theophylline | 1980 |
Inhibition of acetylcholine turnover rate in rat hippocampus and cortex by intraventricular injection of adenosine analogs.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Cerebral Cortex; Hippocampus; Male; Neurotransmitter Agents; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Purinergic; Theophylline | 1982 |
Effects of some naturally-occurring purine ribosides on purinergic receptors in cardiac and smooth muscle.
Topics: Adenosine; Animals; Guanosine; Guinea Pigs; Heart; In Vitro Techniques; Invertebrates; Muscle Contraction; Muscle, Smooth; Muscles; Purine Nucleosides; Receptors, Drug; Receptors, Purinergic; Theophylline | 1982 |
Sites of actions of adenosine in intrinsic cholinergic nerves of ileal longitudinal muscle from guinea pig.
Topics: Adenosine; Animals; Atropine; Binding Sites; Electric Stimulation; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Parasympathetic Nervous System; Tetrodotoxin; Theophylline | 1982 |
Tracheal relaxant and cardiostimulant actions of xanthines can be differentiated from diuretic and CNS-stimulant effects. Role of adenosine antagonism?
Topics: Adenosine; Animals; Bronchodilator Agents; Cardiotonic Agents; Central Nervous System Stimulants; Diuretics; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Theophylline; Trachea; Xanthines | 1982 |
Adenosine mediates sedative action of various centrally active drugs.
Topics: Adenosine; Animals; Antipsychotic Agents; Arousal; Brain; Caffeine; Diazepam; Hypnotics and Sedatives; Phenothiazines; Rats; Receptors, Cell Surface; Receptors, Purinergic; Synapses; Synaptic Transmission; Synaptosomes; Theophylline | 1982 |
Antinociceptive effects in the rat of an adenosine analogue, N6-phenylisopropyladenosine.
Topics: Adenosine; Analgesics; Animals; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Reaction Time; Theophylline | 1983 |
An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Potassium; Rats; Theophylline | 1983 |
Adenosine decreases aspartate and glutamate release from rat hippocampal slices.
Topics: Adenosine; Animals; Aspartic Acid; Corpus Striatum; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Mass Spectrometry; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1984 |
Control of transmitter release in guinea-pig vas deferens by prejunctional P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Norepinephrine; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Vas Deferens | 1984 |
Inhibitors of epidermal cell DNA synthesis in surviving pig skin in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Division; Cyclic AMP; DNA; Epidermal Cells; Epidermis; Epinephrine; Histamine; Hydroxyurea; In Vitro Techniques; Swine; Theophylline | 1980 |
Interactions between catecholamines, methyl xanthines and adenosine in regulation of cyclic AMP accumulation in hamster adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Caffeine; Catecholamines; Cricetinae; Cyclic AMP; Epinephrine; Isoproterenol; Mesocricetus; Norepinephrine; Phentolamine; Theophylline | 1980 |
Activation of human lymphocyte high affinity cyclic AMP phosphodiesterase by culture with 1-methyl-3-isobutylxanthine.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adult; Azides; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Enzyme Activation; Humans; Kinetics; Lymphocytes; Theophylline | 1980 |
Are the anti-allergic actions of theophylline due to antagonism at the adenosine receptor.
Topics: Adenosine; Animals; Histamine Release; Hypersensitivity; In Vitro Techniques; Mast Cells; Rats; Receptors, Cell Surface; Theophylline | 1980 |
Regulatory role of adenosine in antigen-induced histamine release from the lung tissue of actively sensitized guinea pigs.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Antigens; Binding Sites; Calcimycin; Guinea Pigs; Histamine Release; In Vitro Techniques; Lung; Male; Mast Cells; Rats; Theophylline | 1980 |
Inhibition by purine compounds of cyclic GMP-stimulated cyclic AMP phosphodiesterase activity from a particulate fraction of rat striatum.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Corpus Striatum; Cyclic GMP; Dose-Response Relationship, Drug; Hypoxanthines; Inosine; Male; Purines; Rats; Theophylline | 1980 |
Methylxanthines modulate adenosine release from slices of cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Adenosine Triphosphatases; Aminophylline; Animals; Caffeine; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Male; Mice; Ouabain; Theophylline; Xanthines | 1981 |
Pharmacological modification of immunoregulatory T lymphocytes . II. Modulation of T lymphocyte cell surface characteristics.
Topics: Adenosine; Antibodies, Monoclonal; Antigen-Antibody Reactions; Cell Membrane; Cell Separation; Complement Activating Enzymes; Complement C1q; Epitopes; Guanidines; Histocompatibility Antigens Class II; Humans; Imidazoles; Impromidine; Lymphocytes; Receptors, Antigen, B-Cell; Receptors, Histamine H2; T-Lymphocytes; Theophylline | 1982 |
On the mechanism by which theophylline inhibits histamine release from rat mast cells.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Antigens; Cyclic AMP; Cyclic GMP; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Species Specificity; Theophylline | 1982 |
Differential mitogenic effects of methyl isobutyl xanthine and a tumor growth factor on G1-arrested 3T3 T proadipocytes at the predifferentiation GD state and the growth-factor deficiency GS state.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adipose Tissue; Animals; Cell Count; Cell Differentiation; Cell Line; Epidermal Growth Factor; Growth Substances; Interphase; Mice; Mitogens; Structure-Activity Relationship; Theophylline | 1983 |
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Axons; Brain; Clonidine; Diazepam; Dihydroxyphenylalanine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Endogenous adenosine inhibits excitatory transmission in the rat olfactory cortex slice.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Aspartic Acid; Central Nervous System; Cerebral Cortex; Cyclic AMP; Electric Stimulation; Male; Olfactory Pathways; Potassium; Rats; Synaptic Transmission; Theophylline | 1983 |
Agents that activate cyclic AMP-dependent protein kinase inhibit explant culture growth and mitotic activity.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cell Division; Culture Techniques; Cyclic AMP; Dinoprost; Dinoprostone; Enzyme Activation; Epinephrine; Histamine; Mitosis; Prostaglandins E; Prostaglandins F; Protein Kinases; Skin; Swine; Theophylline | 1983 |
Effects of analogues of adenosine and methyl xanthines on insulin sensitivity in soleus muscle of the rat.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Muscles; Phenylisopropyladenosine; Rats; Theophylline | 1984 |
Inhibition of the transport of adenosine, other nucleosides and hypoxanthine in novikoff rat hepatoma cells by methylxanthines, papaverine, N6-cyclohexyladenosine and N6-phenylisopropyladenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Biological Transport, Active; Caffeine; Cell Line; Hypoxanthine; Hypoxanthines; Liver Neoplasms, Experimental; Papaverine; Phenylisopropyladenosine; Rats; Theophylline; Uridine; Xanthines | 1984 |
Behavioral interaction of adenosine and methylxanthines on central purinergic systems.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Caffeine; Drug Interactions; Male; Mice; Mice, Inbred ICR; Motor Activity; Papaverine; Theophylline | 1984 |
Adenosine and adenosine analogues stimulate adenosine cyclic 3', 5'-monophosphate-dependent chloride secretion in the mammalian ileum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Chlorides; Cyclic AMP; Cyclic GMP; Ileum; Kinetics; Male; Phenylisopropyladenosine; Rabbits; Theophylline | 1984 |
Characterization of the adenosine receptor responsible for the inhibition of histamine and SRS-A release from human lung fragments.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Deoxyadenosines; Dideoxyadenosine; Dipyridamole; Guinea Pigs; Hexobendine; Histamine Release; Humans; In Vitro Techniques; Lung; Receptors, Cell Surface; Receptors, Purinergic; SRS-A; Theophylline; Time Factors | 1984 |
Adenosine inhibits and potentiates IgE-dependent histamine release from human lung mast cells by an A2-purinoceptor mediated mechanism.
Topics: Adenosine; Dipyridamole; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Kinetics; Mast Cells; Receptors, Neurotransmitter; Receptors, Purinergic; Structure-Activity Relationship; Theophylline | 1984 |
Pharmacological modification of immunoregulatory T lymphocytes. I. Effect of adenosine, H1 and H2 histamine agonists upon T lymphocyte regulation of B lymphocyte differentiation in vitro.
Topics: Adenosine; B-Lymphocytes; Cell Differentiation; Guanidines; Humans; Imidazoles; Impromidine; Lymphocyte Activation; Plasma Cells; Pokeweed Mitogens; Pyridines; Receptors, Fc; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; T-Lymphocytes; T-Lymphocytes, Regulatory; Theophylline | 1982 |
Inhibitory action of adenosine and adenosine analogs on neurotransmission in the olfactory cortex slice of guinea pig - structure-activity relationships.
Topics: Action Potentials; Adenosine; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Limbic System; Olfactory Nerve; Structure-Activity Relationship; Synapses; Synaptic Transmission; Theophylline | 1980 |
Effects of exogenous adenosine deaminase and erythro-9-(2-hydroxy-3-nonyl) adenine on intracellular cyclic AMP levels in C1300 murine neuroblastoma in tissue culture.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cell Line; Culture Techniques; Cyclic AMP; Dipyridamole; Mice; Neoplasms, Experimental; Neuroblastoma; Nucleoside Deaminases; Theophylline | 1980 |
Adenosine-binding to cerebral preparations in interpretation of adenosine activation of adenosine 3':5'-cyclic monophosphate formation [proceedings].
Topics: 2-Chloroadenosine; Adenosine; Animals; Cattle; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Kinetics; Mitochondria; Radioligand Assay; Rats; Synaptosomes; Theophylline; Tritium | 1980 |
Adenosine-induced alterations in the adenosine 3':5'-monophosphate levels in mammalian epidermis.
Topics: Adenosine; Animals; Animals, Newborn; Cyclic AMP; Dipyridamole; Humans; In Vitro Techniques; Male; Mice; Psoriasis; Skin; Theophylline | 1980 |
Rapid separation and quantitation of 3',5'-cyclic nucleotides and 5'-nucleotides in phosphodiesterase reaction mixtures using high-performance liquid chromatography.
Topics: Adenosine; Adenosine Monophosphate; Animals; Brain; Calmodulin; Cattle; Chromatography, High Pressure Liquid; Microchemistry; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Ribonucleotides; Theophylline | 1980 |
[Relationship between the tonus of the walls of the internal carotid artery and cyclic adenylmonophosphate].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Animals; Carotid Arteries; Carotid Artery, Internal; Cyclic AMP; Dogs; Muscle, Smooth, Vascular; Prostaglandins E; Theophylline; Vasoconstriction | 1980 |
Accumulations of cyclic AMP in adenine-labeled cell-free preparations from guinea pig cerebral cortex: role of alpha-adrenergic and H1-histaminergic receptors.
Topics: Adenosine; Animals; Cell-Free System; Cerebral Cortex; Cyclic AMP; Glutamates; Guinea Pigs; Histamine; Male; Metiamide; Microscopy, Electron; Norepinephrine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Histamine; Receptors, Histamine H1; Theophylline | 1980 |
Inhibitory action of adenosine on histamine- and dopamine-stimulated cardiac contractility and adenylate cyclase in guinea pigs.
Topics: Adenosine; Adenylyl Cyclases; Animals; Calcium; Cyclic AMP; Dopamine Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Myocardial Contraction; Myocardium; Theophylline | 1981 |
Inhibition of nerve-mediated contractions in isolated guinea-pig ileum by 1-methylisoguanosine, a novel purine from a sponge.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Guanosine; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Porifera; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1980 |
Change of cycle AMP level in synaptosomes from cerebral cortex; increase by adenosine derivatives.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Male; Microsomes; Mitochondria; Nucleoside Deaminases; Stimulation, Chemical; Synaptosomes; Theophylline | 1981 |
Inhibitory action of adenosine on synaptic transmission in the hippocampus of the guinea pig in vitro.
Topics: Adenosine; Animals; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Purine Nucleosides; Purine Nucleotides; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Synapses; Synaptic Transmission; Theophylline | 1980 |
Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts.
Topics: Adenosine; Cell Line; Chemical Phenomena; Chemistry; Cyclic AMP; Fibroblasts; Humans; Kinetics; Pteridines; Purines; Structure-Activity Relationship; Theophylline | 1981 |
Induction of Fc gamma receptors on a subpopulation of human T lymphocytes by adenosine and impromidine, an H2-histamine agonist.
Topics: Adenosine; B-Lymphocytes; Guanidines; Humans; Imidazoles; Impromidine; Oxidative Phosphorylation; Protein Biosynthesis; Receptors, Cell Surface; Receptors, Fc; Receptors, Histamine H2; Receptors, Purinergic; Rosette Formation; T-Lymphocytes; Theophylline | 1981 |
Alpha 2 adrenergic amines, adenosine and prostaglandins inhibit lipolysis and cyclic AMP accumulation in hamster adipocytes in the absence of extracellular sodium.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Clonidine; Cricetinae; Cyclic AMP; Lipolysis; Mesocricetus; Phenylisopropyladenosine; Prostaglandins E; Sodium; Theophylline | 1981 |
Adenosine receptor activation by adenine nucleotides requires conversion of the nucleotides to adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cyclic AMP; Humans; In Vitro Techniques; Kinetics; Nucleotidases; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Time Factors | 1980 |
Studies of human plate alpha-granule release in vivo.
Topics: Adenosine; Adult; Anticoagulants; Aspirin; beta-Thromboglobulin; Blood Platelets; Blood Specimen Collection; Bucladesine; Centrifugation; Cytoplasmic Granules; Female; Humans; Male; Middle Aged; Platelet Count; Platelet Factor 4; Prostaglandins E; Temperature; Theophylline; Thrombocytopenia; Time Factors | 1981 |
Regulation of thymocyte proliferation: effects of L-alanine, adenosine and cyclic AMP in vitro.
Topics: Adenosine; Adenosine Deaminase; Alanine; Animals; Cell Division; Cyclic AMP; Cyclopentanes; Guinea Pigs; Kinetics; Male; Mitosis; Pyrrolidinones; Rolipram; T-Lymphocytes; Theophylline | 1981 |
Antagonism of presynaptic adenosine receptors by theophylline 9-beta-D-riboside and 8-phenyltheophylline.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Male; Purine Nucleosides; Rats; Receptors, Adrenergic; Synaptic Transmission; Theophylline; Vas Deferens | 1981 |
The ontogeny of the thyrotropin-thyroid axis in early bovine embryos.
Topics: Adenosine; Animals; Bucladesine; Cattle; Dinoprostone; Embryo, Mammalian; Female; Gestational Age; Indomethacin; Kinetics; Male; Pregnancy; Prostaglandins E; Theophylline; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1981 |
The elevation of mouse thymus cell cyclic adenosine monophosphate (cAMP) by lipopolysaccharide.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cyclic AMP; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Stimulation, Chemical; Theophylline; Thymus Gland | 1981 |
Eritadenine: a new tool for investigation of the adenosine P site in plasma membranes of rat fat cells.
Topics: Adenine; Adenosine; Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Lipolysis; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1981 |
Adenosine and lipolysis.
Topics: Adenosine; Adipose Tissue; Adrenergic Fibers; Animals; Cyclic AMP; Dogs; Female; Lipolysis; Norepinephrine; Theophylline; Vasodilation | 1981 |
Presynaptic inhibition of sympathetic neurotransmission by adenosine in the rat kidney.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Kidney; Male; Norepinephrine; Rats; Rats, Inbred Strains; Renal Circulation; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Vasoconstriction | 1981 |
Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
Topics: Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Guinea Pigs; Homocysteine; Isoproterenol; Kinetics; Methylation; Receptors, Cell Surface; Receptors, Formyl Peptide; S-Adenosylmethionine; Superoxides; Theophylline | 1982 |
Pharmacological investigations on electrically-induced changes of cyclic nucleotides in guinea-pig brain slices.
Topics: Acetylcholine; Adenosine; Animals; Brain; Cyclic AMP; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Norepinephrine; Potassium Chloride; Tetrodotoxin; Theophylline | 1982 |
Adenosine-induced slow ionic currents in the Xenopus oocyte.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Chlorides; Female; Ion Channels; Membrane Potentials; Oocytes; Ovum; Potassium; Theophylline; Xenopus laevis | 1982 |
Evidence for an A2/Ra adenosine receptor in the guinea-pig trachea.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Trachea | 1982 |
Differentiation between bronchodilation and universal adenosine antagonism among xanthine derivatives.
Topics: Adenosine; Animals; Bronchodilator Agents; Dipyridamole; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Male; Mice; Motor Activity; Muscle, Smooth; Myenteric Plexus; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Trachea; Xanthines | 1982 |
Universal adenosine receptor antagonism is neither necessary nor desirable with xanthine antiasthmatics.
Topics: Adenosine; Airway Resistance; Animals; Asthma; Central Nervous System; Diuresis; Dose-Response Relationship, Drug; Humans; Mice; Natriuresis; Neural Inhibition; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline | 1982 |
Effects of caffeine and theophylline on adenosine and benzodiazepine receptors in human brain.
Topics: Adenosine; Binding, Competitive; Brain; Caffeine; Diazepam; Humans; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Purinergic; Theophylline; Xanthines | 1982 |
Bronchodilator mechanisms in bullfrog lung: differences in response to isoproterenol, theophylline and papaverine.
Topics: Adenosine; Animals; Bucladesine; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Kinetics; Lung; Papaverine; Rana catesbeiana; Theophylline | 1982 |
Adenosine--norepinephrine interactions on cyclic AMP generating system in human tumoral brain slices.
Topics: Adenosine; Adult; Aged; Brain Neoplasms; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Glioblastoma; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Propranolol; Theophylline | 1982 |
Pharmacological characterization of purinergic receptors in the rat vas deferens.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Vas Deferens | 1983 |
Abnormal adenosine-induced immunosuppression and cAMP metabolism in T lymphocytes of patients with systemic lupus erythematosus.
Topics: Adenosine; Antigens, Surface; Cyclic AMP; Drug Resistance; Humans; Immune Tolerance; Lupus Erythematosus, Systemic; Molecular Weight; Receptors, Cell Surface; Receptors, Cyclic AMP; Receptors, Fc; Receptors, Purinergic; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Theophylline | 1982 |
Effect of N6-methyladenosine on fat-cell glucose metabolism. Evidence for two modes of action.
Topics: Adenosine; Adipose Tissue; Animals; Coformycin; Cyclic AMP; Fatty Acids; Glucose; Glycerol; In Vitro Techniques; Male; Nucleosides; Oxidation-Reduction; Pentostatin; Rats; Rats, Inbred Strains; Theophylline | 1982 |
Evidence for an A1-adenosine receptor in the guinea-pig atrium.
Topics: Acetylcholine; Adenosine; Animals; Dipyridamole; Electric Stimulation; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Purine receptors in the guinea-pig internal anal sphincter.
Topics: Adenosine; Adenosine Triphosphate; Anal Canal; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Triazines | 1983 |
Modulation of myocardial cyclic AMP and vulnerability to fibrillation in the rat heart.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Coronary Vessels; Cyclic AMP; Heart; Ligation; Myocardium; Rats; Theophylline; Ventricular Fibrillation | 1983 |
Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects.
Topics: Adenosine; Adolescent; Adult; Aged; Airway Resistance; Asthma; Bronchi; Constriction, Pathologic; Cyclic AMP; Forced Expiratory Volume; Guanosine; Humans; Middle Aged; Respiratory Therapy; Sodium Chloride; Theophylline | 1983 |
Action of adenosine on cyclic 3',5'-nucleotides in glomeruli.
Topics: Adenosine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Kinetics; Rats; Serotonin; Theophylline | 1983 |
Purine receptors in the rat anococcygeus muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guanethidine; In Vitro Techniques; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Norepinephrine; Purines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
The ionic basis of adenosine receptor actions on post-ganglionic neurones in the rat.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Autonomic Fibers, Postganglionic; Calcium; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Direct effects of adenosine and adenine nucleotides on isolated human urinary bladder and their influence on electrically induced contractions.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adult; Aged; Atropine; Dipyridamole; Electric Stimulation; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Prostaglandins; Purines; Synaptic Transmission; Theophylline; Urinary Bladder | 1983 |
Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Brain; Caffeine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theobromine; Theophylline; Xanthines | 1983 |
Influence of development and reduction of fat stores on the antilipolytic alpha 2-adrenoceptor in hamster adipocytes: comparison with adenosine and beta-adrenergic lipolytic responses.
Topics: Adenosine; Adipose Tissue; Animals; Clonidine; Cricetinae; Imidazoline Receptors; Isoproterenol; Kinetics; Lipolysis; Male; Mesocricetus; Phenylisopropyladenosine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Theophylline | 1983 |
Possible role of adenosine in the CNS effects of ethanol.
Topics: Adenosine; Alcoholic Intoxication; Alcoholism; Animals; Body Temperature; Central Nervous System; Dipyridamole; Ethanol; Humans; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Substance Withdrawal Syndrome; Theophylline | 1983 |
[3H]adenosine binding to bovine coronary arteries and myocardium.
Topics: Adenosine; Animals; Binding, Competitive; Cattle; Coronary Vessels; In Vitro Techniques; Kinetics; Myocardium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Evidence for the presence of P1- and P2-purinoceptors in rat caecum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Cecum; Cyclic AMP; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Adenosine A1 receptor mediated inhibition of nerve stimulation-induced contractions of the rabbit portal vein.
Topics: Adenosine; Animals; Cocaine; Dextroamphetamine; Dipyridamole; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Portal Vein; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Modulation by unsaturated fatty acids of norepinephrine- and adenosine-induced formation of cyclic AMP in brain slices.
Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Cyclic AMP; Deoxyadenosines; Fatty Acids, Unsaturated; Guinea Pigs; Linoleic Acid; Linoleic Acids; Male; Norepinephrine; Theophylline | 1984 |
Pyrazolo [3,4-d] pyrimidines, a new class of adenosine antagonists.
Topics: Adenosine; Animals; Brain; Cyclic AMP; Guinea Pigs; Pyrazoles; Pyrimidines; Rats; Rats, Inbred Strains; Synaptosomes; Theophylline | 1983 |
Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site.
Topics: Adenosine; Animals; Aorta; Dipyridamole; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Receptors, Cell Surface; Receptors, Purinergic; Sodium Nitrite; Theophylline | 1983 |
Electrophysiological responses to adenosine analogs in rat hippocampus and cerebellum: evidence for mediation by adenosine receptors of the A1 subtype.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebellum; Electrophysiology; Hippocampus; Male; Phenylisopropyladenosine; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Evidence that the P1-purinoceptor in the guinea-pig taenia coli is an A2-subtype.
Topics: Adenosine; Animals; Colon; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Halogenated pyrrolopyrimidine analogues of adenosine from marine organisms: pharmacological activities and potent inhibition of adenosine kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenosine Kinase; Adenylyl Cyclases; Animals; Brain; Bronchodilator Agents; Cardiovascular System; Central Nervous System; Guinea Pigs; In Vitro Techniques; Male; Marine Biology; Mice; Phosphotransferases; Rats; Ribonucleosides; Theophylline; Tubercidin | 1984 |
Colchicine-induced alteration of hormone-stimulated cyclic AMP synthesis in pig skin (epidermis).
Topics: Adenosine; Adenylyl Cyclases; Animals; Colchicine; Cyclic AMP; Cytochalasin B; Epidermis; Epinephrine; Histamine; Hydrocortisone; Swine; Theophylline; Vinblastine | 1984 |
Adenosine attenuation of the electrophysiological effects of isoproterenol on canine cardiac Purkinje fibers.
Topics: Acetylcholine; Action Potentials; Adenosine; Animals; Dogs; Female; Heart Conduction System; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Potassium; Purkinje Fibers; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Behavioral sensitivity to purinergic drugs parallels ethanol sensitivity in selectively bred mice.
Topics: Adenosine; Animals; Behavior, Animal; Body Temperature; Dose-Response Relationship, Drug; Escape Reaction; Ethanol; Mice; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Sleep; Theophylline | 1984 |
Adenosine analogues depress ventilation in rabbit neonates. Theophylline stimulation of respiration via adenosine receptors?
Topics: Adenosine; Age Factors; Animals; Phenylisopropyladenosine; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Theophylline | 1984 |
Adenosine receptors on human inflammatory cells.
Topics: Adenosine; Alprostadil; Cyclic AMP; Humans; Inflammation; Kinetics; Lymphocytes; Prostaglandins E; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Pyrazolo[3,4-d]pyrimidines as adenosine antagonists.
Topics: Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Brain; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Ileum; Intracellular Membranes; Kinetics; Male; Nicotine; Phenylisopropyladenosine; Pyrazoles; Pyrimidines; Rats; Receptors, Cell Surface; Receptors, Purinergic; Synaptosomes; Theophylline | 1984 |
Indirect evidence that purinergic modulation of perivascular adrenergic neurotransmission in the portal vein is a physiological process.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Blood Vessels; Drug Interactions; Guinea Pigs; Histocytochemistry; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Portal Vein; Purines; Quinacrine; Rabbits; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Sympathetic Nervous System; Synaptic Transmission; Theophylline | 1984 |
N6-phenylisopropyladenosine stimulates in normal and inhibits in adrenalectomized rats the low KM cyclic AMP phosphodiesterase in the brain.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenal Insufficiency; Adrenalectomy; Animals; Cerebral Cortex; In Vitro Techniques; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline | 1984 |
Evidence for an inhibitory prejunctional P1-purinoceptor in the rat portal vein with characteristics of the A2 rather than of the A1 subtype.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Synaptic Transmission; Theophylline | 1984 |
Dual effect of (-)-N6-phenylisopropyl adenosine on guinea-pig trachea.
Topics: Adenosine; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Carbachol; Chromones; Drug Interactions; Guinea Pigs; In Vitro Techniques; Norepinephrine; Phenylisopropyladenosine; SRS-A; Theophylline; Trachea | 1984 |
Adenosine causes contractions in spiral strips and relaxations in transverse strips of guinea-pig trachea: studies on mechanism of action.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Theophylline; Trachea | 1984 |
Adenosine as a bronchoconstrictor mediator in asthma and its antagonism by methylxanthines.
Topics: Adenosine; Asthma; Bronchi; Humans; Immunoglobulin E; Mast Cells; Theophylline; Xanthines | 1984 |
Theophylline antagonizes cardiovascular responses to dipyridamole in man without affecting increases in plasma adenosine.
Topics: Adenosine; Adult; Blood Flow Velocity; Blood Pressure; Capillaries; Catecholamines; Dipyridamole; Heart Rate; Hemodynamics; Humans; Male; Microcirculation; Skin; Theophylline | 1984 |
8-Phenyltheophylline potentiates the electrical activity evoked in hippocampal slices.
Topics: Adenosine; Animals; Corpus Striatum; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Theophylline | 1984 |
Antagonism of the behavioral effects of L-phenylisopropyladenosine (L-PIA) by caffeine and its metabolites.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Conditioning, Psychological; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Theophylline; Xanthines | 1984 |
Prolonged inhibition of respiration following acute hypoxia in glomectomized cats.
Topics: Acute Disease; Adenosine; Animals; Carotid Body; Cats; Denervation; Extracellular Space; Hydrogen-Ion Concentration; Hypoxia; Medulla Oblongata; Phrenic Nerve; Respiration; Theophylline | 1984 |
Relaxation of rings of canine cerebral artery produced by adenosine and its analogues.
Topics: Adenosine; Animals; Apamin; Cerebral Arteries; Dogs; Female; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Serotonin; Theophylline; Vasodilation | 1984 |
Antagonism of enkephalin action on acetylcholine release by methylxanthines: lack of a purine link.
Topics: Acetylcholine; Adenosine; Animals; Caffeine; Cerebral Cortex; Enkephalins; Guinea Pigs; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Rats; Theophylline; Xanthines | 1983 |
Adenosine antagonism as an alternative mechanism of action of methylxanthines in asthma.
Topics: Adenosine; Adenosine Monophosphate; Airway Resistance; Asthma; Bronchi; Dose-Response Relationship, Drug; Guanosine; Histamine; Humans; Inosine; Theophylline | 1983 |
Inhibition of noradrenaline release from hippocampal slices by a stable adenosine analogue.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Secretory Rate; Theophylline | 1983 |
Adenosine strongly potentiates pressor responses to nicotine in rats.
Topics: Adenosine; Animals; Blood Pressure; Caffeine; Drug Synergism; Electric Stimulation; Male; Nicotine; Phenylephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline | 1984 |
Regulation of thymocyte proliferation by endogenous adenosine and adenosine deaminase.
Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Dipyridamole; DNA; Guinea Pigs; Lymphocyte Activation; Nucleoside Deaminases; Phenylisopropyladenosine; T-Lymphocytes; Theophylline | 1983 |
Adenosine reduces catecholamine contractile responses in oxygenated and hypoxic atria.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Atrial Function; Atropine; Epinephrine; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Theophylline | 1983 |
Interaction between adenosine and inotropic interventions in guinea pig atria.
Topics: Adenosine; Animals; Atrial Function; Electric Stimulation; Guinea Pigs; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Potassium; Propranolol; Theophylline | 1983 |
Mediation by the corticostriatal input of the in vivo increase in rat striatal acetylcholine content induced by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain; Corpus Striatum; Female; Kinetics; Rats; Rats, Inbred Strains; Theophylline | 1983 |
On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat.
Topics: Adenosine; Animals; Apomorphine; Brain; Drug Synergism; Male; Motor Activity; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Rotation; Theophylline; Xanthines | 1983 |
Heparin inactivation during blood storage: its prevention by blood collection in citric acid, theophylline, adenosine, dipyridamole-C.T.A.D. mixture.
Topics: Adenosine; Blood Coagulation Tests; Blood Preservation; Blood Specimen Collection; Centrifugation; Citrates; Citric Acid; Dipyridamole; Heparin; Humans; In Vitro Techniques; Temperature; Theophylline; Time Factors | 1983 |
Adenosine and ATP effects on isolated guinea pig gallbladder.
Topics: Adenosine; Adenosine Triphosphate; Animals; Culture Techniques; Drug Interactions; Gallbladder; Guanosine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Theophylline; Thionucleosides | 1983 |
Influence of adenosine on the vascular responses to sympathetic nerve stimulation in the canine subcutaneous adipose tissue.
Topics: Adenine; Adenosine; Adipose Tissue; Animals; Body Temperature; Dipyridamole; Dogs; Electric Stimulation; Female; Homeostasis; Inosine; Norepinephrine; Propranolol; Regional Blood Flow; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1983 |
Impaired blood flow autoregulation in nonfiltering kidneys: effects of theophylline administration.
Topics: Adenosine; Animals; Dogs; Homeostasis; Ischemia; Kidney; Renal Circulation; Theophylline; Vascular Resistance | 1983 |
Novel form of drug-dependence--on adenosine in guinea pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Humans; Ileum; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Substance-Related Disorders; Theophylline | 1983 |
Effects of theophylline on adenosine-induced respiratory depression in the preterm rabbit.
Topics: Adenosine; Animals; Animals, Newborn; Gestational Age; Phenylisopropyladenosine; Rabbits; Respiration; Theophylline | 1984 |
Stimulation of electrolyte secretion in rabbit colon by adenosine.
Topics: Adenosine; Animals; Bicarbonates; Chlorides; Colon; Electric Conductivity; Furosemide; In Vitro Techniques; Nucleotides, Cyclic; Rabbits; Sodium; Structure-Activity Relationship; Theophylline | 1984 |
Adenosine-induced bronchoconstriction in asthma. Antagonism by inhaled theophylline.
Topics: Adenosine; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Drug Antagonism; Female; Forced Expiratory Volume; Histamine; Humans; Male; Theophylline | 1984 |
Intracellular adenosine in isolated rat liver cells.
Topics: Adenosine; Adenosine Deaminase; Animals; Intracellular Membranes; Liver; Rats; Rats, Inbred Strains; Theophylline | 1984 |
Mitochondrial oxidative phosphorylation: tissue oxygen sensor for regulation of coronary flow.
Topics: 2,4-Dinitrophenol; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Amobarbital; Animals; Coronary Circulation; Creatine; Dinitrophenols; Energy Metabolism; In Vitro Techniques; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Rats; Rats, Inbred Strains; Theophylline | 1984 |
Adenosine and adenosine analogues increase blood flow in oral mucosa.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Dipyridamole; Mouth Mucosa; Phenylisopropyladenosine; Purines; Regional Blood Flow; Theophylline; Vascular Resistance | 1984 |
The influence of concurrently administered theophylline, ouabain and hypocapnia on coronary flow perturbations in the perfused guinea pig heart.
Topics: Adenosine; Alkalosis; Animals; Carbon Dioxide; Coronary Circulation; Guinea Pigs; Hydrogen; Ouabain; Potassium; Theophylline | 1981 |
Contribution of adenosine to arteriolar autoregulation in striated muscle.
Topics: Adenosine; Animals; Arteries; Arterioles; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscles; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline | 1983 |
An unusual excitatory action of adenosine on the ventricular muscle of the South African clawed toad (Xenopus laevis).
Topics: Adenosine; Animals; Electric Stimulation; Heart Atria; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Theophylline; Xenopus laevis | 1983 |
Evidence in support of the P1/P2 purinoceptor hypothesis in the guinea-pig taenia coli.
Topics: Adenine Nucleotides; Adenosine; Animals; Apamin; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; Male; Muscle Contraction; Purines; Receptors, Drug; Receptors, Purinergic; Theophylline | 1981 |
8-phenyltheophylline: a potent P1-purinoceptor antagonist.
Topics: Adenosine; Animals; Basilar Artery; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Rabbits; Receptors, Drug; Receptors, Purinergic; Theophylline | 1981 |
Evidence for stereospecificity of the P1-purinoceptor.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Azides; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Receptors, Drug; Receptors, Purinergic; Stereoisomerism; Theophylline; Trachea | 1982 |
Modulation of the vasoconstrictor response to adrenergic stimulation by nucleosides and nucleotides.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Male; Norepinephrine; Nucleosides; Nucleotides; Potassium Chloride; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline; Vasoconstriction | 1982 |
Can ATP stimulate P1-receptors in guinea-pig atrium without conversion to adenosine?
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biotransformation; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Receptors, Drug; Receptors, Purinergic; Theophylline | 1982 |
Two T lymphocyte subpopulations isolated from human peripheral blood following "in vitro" treatment with adenosine.
Topics: Adenine; Adenosine; Adult; Animals; Humans; In Vitro Techniques; Phytohemagglutinins; Rosette Formation; Sheep; T-Lymphocytes; Theophylline | 1980 |
Distribution of P1- and P2-purinoceptors in the guinea-pig and frog heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dipyridamole; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rana pipiens; Receptors, Drug; Receptors, Purinergic; Theophylline | 1981 |
Adenosine receptor lymphocytes in humoral immunodeficiency.
Topics: Adenosine; Adolescent; Adult; Agammaglobulinemia; Aged; Child; Humans; Immunoglobulin G; Immunoglobulin M; Leukocyte Count; Middle Aged; Receptors, Immunologic; T-Lymphocytes; Theophylline | 1981 |
The effect of a benzodiazepine, flurazepam, on the response of in vitro skeletal muscle preparations to muscle relaxants: are purines or their receptors involved?
Topics: Adenosine; Animals; Benzodiazepines; Flurazepam; In Vitro Techniques; Male; Muscles; Neuromuscular Junction; Purines; Rana pipiens; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Purinergic; Succinylcholine; Theophylline; Tubocurarine | 1982 |
Binding of 2',5'-dideoxyadenosine to brain membranes. Comparison to P-site inhibition of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Brain; Deoxyadenosines; Dideoxyadenosine; In Vitro Techniques; Kinetics; Membranes; Rats; Rats, Inbred Strains; Theophylline; Vidarabine | 1982 |
Pharmacological induced depression of E-rosette forming cells (RFC) of normal healthy subjects. Restoration by levamisole and thymopoietin pentapeptide.
Topics: Adenosine; Humans; Immune Adherence Reaction; Levamisole; Lymphocytes; Peptide Fragments; Rosette Formation; Theophylline; Thymopentin; Thymopoietins; Thymus Hormones | 1980 |
Potentiation of arginine-induced glucagon secretion by adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Drug Synergism; Glucagon; Insulin; Insulin Secretion; Male; Pancreas; Phenylisopropyladenosine; Rats; Theophylline | 1981 |
Inhibitory effect of adenosine and adenine nucleotides on potassium-evoked efflux of [3H]-noradrenaline from the rat isolated heart: lack of relationship to prostaglandins.
Topics: Adenine Nucleotides; Adenosine; Animals; Calcium; In Vitro Techniques; Indomethacin; Male; Myocardium; Norepinephrine; Potassium; Prostaglandins; Rats; Rats, Inbred Strains; Theophylline; Tritium; Tyramine | 1980 |
Augmentation by theophylline of [3H]purine release from vascular adrenergic nerves: evidence for presynaptic autoinhibition.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Vessels; Dipyridamole; In Vitro Techniques; Male; Papaverine; Phentolamine; Potassium Chloride; Purines; Rabbits; Sympathetic Nervous System; Synapses; Theophylline | 1982 |
Sedative and anticonvulsant effects of adenosine analogs in mouse and rat.
Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Body Temperature; Dose-Response Relationship, Drug; Drug Interactions; Hypnotics and Sedatives; Male; Mice; Rats; Rats, Inbred Strains; Theophylline | 1982 |
[Interrelation of the regulatory effects of adenosine, ATP and fluoride on heart adenylate cyclase].
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Enzyme Activation; Fluorides; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Myocardium; Rabbits; Sodium Fluoride; Theophylline | 1982 |
Control of coronary flow by local factors during hypoxia with and without a fall in O2 consumption.
Topics: Adenosine; Animals; Blood Flow Velocity; Coronary Circulation; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hypoxia; Male; Oxygen Consumption; Perfusion; Theophylline; Vasodilator Agents | 1982 |
Role of mitochondrial oxidative phosphorylation in regulation of coronary blood flow.
Topics: Adenosine; Amobarbital; Animals; Calcium; Coronary Circulation; Hypoxanthines; Hypoxia; Inosine; Lactates; Lactic Acid; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Physical Exertion; Rats; Theophylline | 1982 |
Rat adipocyte lipoprotein lipase activity is inhibited by theophylline and stimulated by inosine through adenosine-independent mechanisms.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Animals; Inosine; Kinetics; Lipoprotein Lipase; Male; Rats; Rats, Inbred Strains; Theophylline | 1982 |
Modulation of the release of acetylcholine from ileal synaptosomes by adenosine and adenosine 5'-triphosphate.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Calcium; Female; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Receptors, Nicotinic; Synaptosomes; Temperature; Theophylline | 1982 |
Adenosine receptors mediating cardiac depression.
Topics: 2-Chloroadenosine; Adenosine; Animals; Depression, Chemical; Guinea Pigs; Heart Atria; Male; Myocardial Contraction; Phenylisopropyladenosine; Theophylline; Xanthines | 1982 |
Effects of adenosine and its derivatives on the canine intestinal vasculature.
Topics: Adenosine; Animals; Dogs; Dose-Response Relationship, Drug; Female; Intestine, Small; Male; Muscle, Smooth, Vascular; Oxygen Consumption; Regional Blood Flow; Theophylline | 1981 |
Endogenous adenosine inhibits lipolysis induced by nerve stimulation without inhibiting noradrenaline release in canine subcutaneous adipose tissue in vivo.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adipose Tissue; Animals; Dipyridamole; Dogs; Electric Stimulation; Female; Lipolysis; Norepinephrine; Sympathetic Nervous System; Theophylline; Vasodilation | 1981 |
Theophylline does not affect morphine inhibition of the isolated vas deferens.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Morphine; Theophylline; Vas Deferens | 1981 |
Evidence for adenosine mediation of atrioventricular block in the ischemic canine myocardium.
Topics: Adenosine; Aminophylline; Animals; Coronary Disease; Dipyridamole; Dogs; Electrocardiography; Female; Heart Block; Heart Conduction System; Male; Propranolol; Theophylline | 1981 |
Effect of adenosine on carotid chemoreceptor activity in the cat.
Topics: Adenosine; Aminophylline; Animals; Carotid Arteries; Cats; Chemoreceptor Cells; Electrophysiology; Female; Male; Naloxone; Theophylline | 1981 |
Methylxanthines antagonize adenosine but not morphine inhibition in guinea pig ileum.
Topics: Adenosine; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Theophylline; Xanthines | 1981 |
Vascular response of the chicken hindlimb to vasoactive agents, asphyxia, and exercise.
Topics: Acetylcholine; Adenosine; Animals; Chickens; Dose-Response Relationship, Drug; Histamine; Male; Muscles; Norepinephrine; Perfusion; Phenoxybenzamine; Physical Exertion; Prostaglandins E; Theophylline; Vascular Resistance; Vasomotor System | 1981 |
Adenosine antagonism, a less desirable characteristic of xanthine asthma drugs?
Topics: Adenosine; Animals; Asthma; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Rats; Theophylline; Xanthines | 1981 |
Evidence that morphine and opioid peptides do not share a common pathway with adenosine in inhibiting acetylcholine release from isolated intestine.
Topics: Acetylcholine; Adenosine; Animals; Electric Stimulation; Endorphins; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Intestines; Morphine; Muscle, Smooth; Myenteric Plexus; Theophylline | 1981 |
Action of coenzyme A on adenine derivative receptors in isolated tissues.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coenzyme A; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Rabbits; Rats; Receptors, Drug; Theophylline | 1980 |
Effect of adenosine triphosphate and related agents on [14C]choline uptake by guinea-pig neocortex synaptosomes [proceedings].
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Cerebral Cortex; Choline; Guanosine Triphosphate; Guinea Pigs; Synaptosomes; Theophylline | 1980 |
Role of adenosine in exercise vasodilation in dog gracilis muscle.
Topics: Adenosine; Animals; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Muscle Contraction; Muscles; Quinidine; Theophylline; Vasodilation | 1980 |
Adenosine inhibition of gamma-aminobutyric acid release from slices of rat cerebral cortex.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cerebral Cortex; Depression, Chemical; Dipyridamole; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Potassium; Rats; Theophylline; Time Factors | 1980 |
Role of adenosine in local control of intestinal circulation in the dog.
Topics: Adenosine; Animals; Blood Flow Velocity; Dipyridamole; Dogs; Fasting; Food; Homeostasis; Hyperemia; Injections, Intra-Arterial; Intestines; Mesenteric Arteries; Oxygen; Theophylline; Vasodilation | 1980 |
Effect of varying pH [H+] on the metabolism of adenosine in isolated heart cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Chick Embryo; Hydrogen-Ion Concentration; Hypoxanthines; Inosine; Myocardium; Theophylline | 1980 |
Inhibition of fundic strips from guinea-pig stomach: the effect of theophylline on responses to adenosine, ATP and intramural nerve stimulation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Stomach; Theophylline | 1980 |
Adenosine as a possible mediator of metabolic control of glomerular filtration rate.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Dipyridamole; Glomerular Filtration Rate; Kidney Tubules, Proximal; Kinetics; Osmolar Concentration; Rats; Theophylline | 1980 |
Reactivity of isolated canine cerebral arteries to adenine nucleotides and adenosine.
Topics: Adenine Nucleotides; Adenosine; Animals; Cerebral Arteries; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Theophylline | 1980 |
Metal ion and guanine nucleotide regulation of the inhibition of lung adenylate cyclase by adenosine analogs.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Guanine Nucleotides; Guinea Pigs; Kinetics; Lung; Magnesium; Male; Manganese; Theophylline | 1980 |
Effects of diazepam on adenosine and acetylcholine release from rat cerebral cortex: further evidence for a purinergic mechanism in action of diazepam.
Topics: Acetylcholine; Adenosine; Animals; Brain; Diazepam; Male; Pentobarbital; Purines; Rats; Theophylline | 1980 |
Aminophylline and theophylline derivatives as antagonists of neuronal depression by adenosine: a microiontophoretic study.
Topics: Adenosine; Aminophylline; Animals; Depression, Chemical; Ethylenediamines; Iontophoresis; Male; Neurons; Rats; Theophylline | 1980 |
Effects of adenosine and related compounds on an inhibitory process in rat cerebral cortex.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Animals; Cerebral Cortex; Dipyridamole; Evoked Potentials; gamma-Aminobutyric Acid; Hexobendine; Male; Neural Inhibition; Rats; Theophylline | 1980 |
Nephrotoxicity from contrast media: attenuation with theophylline.
Topics: Adenosine; Contrast Media; Creatinine; Diatrizoate; Glomerular Filtration Rate; Humans; Iopamidol; Kidney; Kidney Diseases; Osmolar Concentration; Phosphodiesterase Inhibitors; Theophylline | 1995 |
Nephrotoxicity from contrast media: attenuation with theophylline.
Topics: Adenosine; Age Factors; Contrast Media; Humans; Kidney; Kidney Diseases; Middle Aged; Phosphodiesterase Inhibitors; Placebos; Purinergic P1 Receptor Antagonists; Randomized Controlled Trials as Topic; Theophylline | 1995 |
Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor.
Topics: Adenosine; Animals; Cell Size; Cell Survival; Cells, Cultured; Glucose; Heart; Myocardial Ischemia; Myocardium; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rabbits; Theophylline; Time Factors | 1994 |
Differential effects of ATP- and 2-methylthioATP-induced relaxation in guinea pig coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Coronary Vessels; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinergic Antagonists; Theophylline; Thionucleotides | 1994 |
Regulation of adenosine receptor function by theophylline in rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Animals; Aorta; Colforsin; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norbornanes; Rats; Receptors, Purinergic P1; Theophylline | 1994 |
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocardial Ischemia; Myocardium; Naphthalenes; Phenethylamines; Phenylisopropyladenosine; Polycyclic Compounds; Protein Kinase C; Purinergic Antagonists; Pyruvates; Pyruvic Acid; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors; Trypan Blue; Xanthines | 1994 |
Role of adenosine in vasodilation of epimyocardial coronary microvessels during reduction in perfusion pressure.
Topics: Adenosine; Adenosine Deaminase; Administration, Topical; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Infusion Pumps; Male; Pressure; Theophylline; Vasodilation | 1994 |
A1 adenosine receptors differentially regulate the N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated components of hippocampal excitatory postsynaptic current in a Ca2+/Mg(2+)-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Calcium; Hippocampus; In Vitro Techniques; Ion Channels; Magnesium; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synapses; Theophylline | 1995 |
Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.
Topics: Adenosine; Amino Acid Oxidoreductases; Animals; Bucladesine; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression; Hematopoietic Stem Cells; Humans; Interferon-gamma; Kinetics; Leishmania; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nitric Oxide Synthase; Recombinant Proteins; RNA, Messenger; Theophylline; Tumor Necrosis Factor-alpha | 1995 |
Effect of adenosine and adenosine agonists on amylase release from rat pancreatic lobules.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amylases; Animals; Atropine; Dipyridamole; Dose-Response Relationship, Drug; Pancreatin; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Secretory Rate; Theophylline | 1995 |
Purinergic inhibition of GABA and glutamate release in the thalamus: implications for thalamic network activity.
Topics: Adenosine; Animals; Bicuculline; Electric Conductivity; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Quinoxalines; Rats; Receptors, Purinergic P1; Synapses; Thalamus; Theophylline | 1995 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Xanthines | 1995 |
Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
A role for mast cells in adenosine A3 receptor-mediated hypotension in the rat.
Topics: Adenosine; Animals; Antihypertensive Agents; Apnea; Cromolyn Sodium; Dose-Response Relationship, Drug; Hypotension; Injections, Intravenous; Male; Mast Cells; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Theophylline | 1995 |
Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline.
Topics: Adenosine; Animals; Blood Pressure; Blood Proteins; Heart Rate; Male; Models, Chemical; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1995 |
The purinoceptors of the guinea-pig isolated taenia caeci.
Topics: Adenosine; Animals; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Theophylline | 1995 |
8-substituted adenosine and theophylline-7-riboside analogues as potential partial agonists for the adenosine A1 receptor.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cells, Cultured; Heart Rate; In Vitro Techniques; Kinetics; Purinergic P1 Receptor Agonists; Rats; Theophylline; Xanthines | 1995 |
Effects of N6-cyclopentyladenosine on afterdepolarizations and triggered activity induced by isoproterenol in guinea pig papillary muscle.
Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Papillary Muscles; Theophylline | 1995 |
Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade.
Topics: Adenosine; Animals; Blood Flow Velocity; Cats; Choroid; Hemodynamics; Hyperemia; Ischemia; Microspheres; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Reperfusion; Retinal Vessels; Theophylline | 1995 |
Endogenous adenosine modulates alpha 2- but not alpha 1-adrenergic constriction of coronary arterioles.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Arterioles; Azepines; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart Rate; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Phenylephrine; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reference Values; Theophylline; Vasoconstriction | 1995 |
Role of cyclic AMP in stimulation-evoked release of 3H-noradrenaline from rabbit isolated ear artery.
Topics: Adenosine; Animals; Arteries; Colforsin; Cyclic AMP; Ear; Electric Stimulation; Female; Male; Naphthyridines; Norepinephrine; Phosphodiesterase Inhibitors; Pyrimidines; Rabbits; Theophylline; Tritium | 1995 |
Adenosine modulates hypoxia-induced atrial natriuretic peptide release in fetal sheep.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Blood Pressure; Fetal Blood; Gases; Heart Rate; Hemoglobins; Hydrogen-Ion Concentration; Hypoxia; Purinergic P1 Receptor Antagonists; Sheep; Theophylline | 1995 |
Direct in vivo observation of subendocardial arteriolar response during reactive hyperemia.
Topics: Adenosine; Animals; Arginine; Arterioles; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hyperemia; Male; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Theophylline; Vasodilation | 1995 |
Bidirectional effects of aminophylline on myocardial ischemia.
Topics: Adenosine; Aminophylline; Animals; Coronary Circulation; Dogs; Heart; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Prazosin; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P1; Reproducibility of Results; Theophylline | 1995 |
Evidence for, and characterization of, a lipopolysaccharide-inducible adenosine A2 receptor in human tracheal gland serous cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Cyclic AMP; Dipyridamole; Exocrine Glands; Humans; Lipopolysaccharides; Phenylisopropyladenosine; Proteinase Inhibitory Proteins, Secretory; Proteins; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Serine Proteinase Inhibitors; Theophylline; Trachea | 1995 |
Adenosine enhances nitric oxide production by vascular endothelial cells.
Topics: Adenosine; Animals; Arginine; Carotid Arteries; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Nitric Oxide; omega-N-Methylarginine; Saphenous Vein; Swine; Theophylline | 1995 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline | 1995 |
Role of adenosine in NMDA receptor modulation in the cerebral cortex of an anoxia-tolerant turtle (Chrysemys picta belli).
Topics: Adenosine; Animals; Calcium; Cerebral Cortex; Female; Fluorometry; Fura-2; Glutamates; Hypoxia, Brain; Male; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Theophylline; Turtles | 1995 |
Theophylline for the treatment of atrioventricular block after myocardial infarction.
Topics: Adenosine; Adult; Aged; Electrocardiography; Heart Block; Humans; Male; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Theophylline | 1995 |
Flow cytometric evaluation of platelet activation in blood collected into EDTA vs. Diatube-H, a sodium citrate solution supplemented with theophylline, adenosine, and dipyridamole.
Topics: Adenosine; Adult; Anticoagulants; Citrates; Citric Acid; Dipyridamole; Edetic Acid; Female; Flow Cytometry; Humans; Male; Platelet Activation; Solutions; Theophylline | 1995 |
Theophylline-induced nociceptive behavioral response in mice: possible indirect interaction with spinal N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Male; Mice; Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Spinal Cord; Substance P; Theophylline | 1993 |
Occupancy of P2 purinoceptors with unique properties modulates the function of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Triphosphate; Cell Membrane; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Iloprost; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Purinergic; Signal Transduction; Theophylline | 1993 |
Adenosine decreases permeability of in vitro endothelial monolayers.
Topics: Adenosine; Animals; Capillary Permeability; Cattle; Cells, Cultured; Dextrans; Dipyridamole; Endothelium, Vascular; Polyethylene Glycols; Purinergic Antagonists; Receptors, Purinergic; Theophylline | 1993 |
Adenosine inhibits efferent function of extrinsic capsaicin-sensitive sensory nerves in the enteric nervous system.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Capsaicin; Electric Stimulation; Electrophysiology; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mesentery; Muscle Contraction; Myenteric Plexus; Nerve Fibers; Neurons, Afferent; Neurons, Efferent; Substance P; Theophylline | 1993 |
Spinal adenosine modulates capsaicin-induced depressor reflex: involvement of adenosine A2 receptor.
Topics: Adenosine; Animals; Blood Pressure; Capsaicin; Hemodynamics; Injections, Spinal; Male; Nerve Fibers; Neurons, Afferent; Peptide Fragments; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex; Spinal Cord; Substance P; Theophylline | 1993 |
Blockade of adenosine receptors during ischaemia increases systolic dysfunction but does not affect diastolic creep in stunned myocardium.
Topics: Adenosine; Animals; Cats; Heart; Hemodynamics; Male; Myocardial Contraction; Myocardial Stunning; Purinergic P1 Receptor Antagonists; Theophylline; Ventricular Dysfunction, Left | 1994 |
Characterization of the adenosine A1 receptor-activated potassium current in rat locus ceruleus neurons.
Topics: 4-Aminopyridine; Adenosine; Animals; Barium; Dose-Response Relationship, Drug; Glyburide; Locus Coeruleus; Male; Membrane Potentials; Neurons; Potassium Channels; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Theophylline | 1995 |
Inhibitory effect of adenosine on electrical activity of frog melanotrophs mediated through A1 purinergic receptors.
Topics: Action Potentials; Adenosine; alpha-MSH; Animals; Cells, Cultured; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Membrane Potentials; Patch-Clamp Techniques; Pertussis Toxin; Phenylisopropyladenosine; Pituitary Gland; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinazolines; Rana ridibunda; Tachyphylaxis; Theophylline; Triazoles; Virulence Factors, Bordetella | 1994 |
The role of adenosine in promoting cardiac beta-adrenergic subsensitivity in aging humans.
Topics: Adenosine; Adult; Aged; Aging; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Norepinephrine; Posture; Purinergic P1 Receptor Antagonists; Renin; Theophylline | 1995 |
Effects of xanthine derivatives in a light/dark test in mice and the contribution of adenosine receptors.
Topics: Adenosine; Animals; Antihypertensive Agents; Anxiety; Behavior, Animal; Caffeine; Darkness; Drug Interactions; Light; Male; Mice; Phenethylamines; Purinergic P1 Receptor Antagonists; Structure-Activity Relationship; Theophylline; Xanthines | 1994 |
Effects of ethanol-induced changes in adenosine transport on cAMP production in rat hepatocytes.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport, Active; Cells, Cultured; Cyclic AMP; Ethanol; Liver; Rats; Receptors, Glucagon; Receptors, Purinergic P1; Theophylline; Virulence Factors, Bordetella | 1993 |
Relative binding orientations of adenosine A1 receptor ligands--a test case for Distributed Multipole Analysis in medicinal chemistry.
Topics: Adenosine; Computer Graphics; Drug Design; Electrochemistry; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Xanthines | 1995 |
Role of endothelium in hyperpolarization of coronary smooth muscle by adenosine and its analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Swine; Theophylline; Vasodilator Agents | 1995 |
Pronounced antiarrhythmic effects of preconditioning in anaesthetized dogs: is adenosine involved?
Topics: Adenosine; Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart; Heart Rate; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion; Purinergic P1 Receptor Antagonists; Theophylline; Time Factors; Vascular Resistance | 1995 |
[Mutagenesis, antimutagenesis and the cellular regulatory system].
Topics: Adenosine; Antimutagenic Agents; Caffeine; Colchicine; Cyclic AMP; Mutagenesis; Plant Cells; Plants; Seeds; Theophylline | 1995 |
Endogenous adenosine attenuates myocardial stunning by antiadrenergic effects exerted during ischemia and not during reperfusion.
Topics: Adenosine; Animals; Cats; Coronary Circulation; Doxazosin; Heart; Hemodynamics; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Propranolol; Purinergic P1 Receptor Antagonists; Sympathetic Nervous System; Theophylline | 1995 |
The role of acetate as a potential mediator of the effects of ethanol in the brain.
Topics: Acetates; Adenosine; Animals; Brain; Ethanol; Evoked Potentials; Hippocampus; In Vitro Techniques; Ion-Selective Electrodes; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1995 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Theophylline; Triazoles; Vasodilator Agents; Xanthines | 1995 |
Effects of adenosine receptor agonists and antagonists on physostigmine-induced yawning.
Topics: Adenosine; Animals; Atropine; Male; Physostigmine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Yawning | 1995 |
Adenosine antagonists have differential effects on induction of long-term potentiation in hippocampal slices.
Topics: Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1995 |
Characterization of the facilitatory prejunctional purinoceptor on adrenergic nerves of the rabbit ear artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adrenergic Fibers; Animals; Arteries; Ear; Female; In Vitro Techniques; Male; Norepinephrine; Purinergic Agonists; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Theophylline | 1995 |
Attenuation of traumatic cell death by an adenosine A1 agonist in rat hippocampal cells.
Topics: Adenosine; Animals; Brain Injuries; Cell Death; Cells, Cultured; Culture Media; Dizocilpine Maleate; Extracellular Space; Hippocampus; Rats; Rats, Sprague-Dawley; Theophylline | 1995 |
Anticonvulsant effects of intracerebroventricular adenocard in theophylline-induced seizures.
Topics: Adenosine; Aminophylline; Animals; Cerebral Ventricles; Male; Rats; Rats, Sprague-Dawley; Seizures; Theophylline | 1995 |
Acadesine reduces myocardial infarct size by an adenosine mediated mechanism.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Coronary Circulation; Extracellular Space; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Rabbits; Receptors, Purinergic P1; Regional Blood Flow; Ribonucleosides; Theophylline | 1995 |
Dopamine-independent and adenosine-dependent mechanisms involved in the effects of N-methyl-D-aspartate on motor activity in mice.
Topics: Adenosine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Antagonists; Drug Interactions; Haloperidol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Motor Activity; N-Methylaspartate; Reserpine; Theophylline | 1995 |
Role of adenosine A1 receptors in inhibition of receptor-stimulated cyclic AMP production by ethanol in hepatocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic AMP; Drug Interactions; Ethanol; Glucagon; Liver; Male; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1994 |
Action of adenosine receptor antagonists on the cardiovascular response to defence area stimulation in the rat.
Topics: Adenosine; Animals; Behavior, Animal; Blood Pressure; Ethanol; Heart Rate; Hemodynamics; Hypothalamus; In Vitro Techniques; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1994 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyperemia; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Nitroprusside; Oxygen Consumption; Physical Conditioning, Animal; Pinacidil; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Systole; Theophylline; Vasodilation | 1995 |
Differentiation of the peripherally mediated from the centrally mediated influences of adenosine in the rat during systemic hypoxia.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Blood Gas Analysis; Blood Pressure; Heart Rate; Hemodynamics; Hypoxia; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Respiration; Theophylline; Vascular Resistance; Vasodilation | 1994 |
A paradoxical inhibitory effect of xanthines on hippocampal excitability in calcium-free media.
Topics: Adenosine; Animals; Baclofen; Calcium; Carbamazepine; Culture Media; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Wistar; Theophylline; Xanthines | 1994 |
Adenosine modulation of primed human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Antihypertensive Agents; Drug Interactions; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Receptors, Purinergic P1; Superoxides; Theophylline | 1994 |
Strain-related differences in adenosine receptor density and in behavioral sensitivity to adenosine analogs in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Male; Membranes; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Motor Activity; Platelet Aggregation Inhibitors; Radioligand Assay; Receptors, Purinergic P1; Species Specificity; Theophylline | 1994 |
Metabolic determinants of defibrillation. Role of adenosine.
Topics: Adenosine; Animals; Catecholamines; Dogs; Electric Countershock; Lactates; Lactic Acid; Theophylline; Ventricular Fibrillation | 1995 |
Endogenous adenosine exerts inhibitory effects upon the development of spreading depression and glutamate release induced by microdialysis with high K+ in rat hippocampus.
Topics: Adenosine; Animals; Cortical Spreading Depression; Dipyridamole; Glutamic Acid; Hippocampus; Male; Microdialysis; Potassium; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Theophylline; Thioinosine; Xanthines | 1994 |
Contribution of prostaglandins in hypoxia-induced vasodilation in isolated rabbit hearts. Relation to adenosine and KATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cyclic AMP; Diclofenac; Epoprostenol; Heart; Hypoxia; Myocardium; Potassium Channels; Prostaglandins; Rabbits; Theophylline; Vasodilation | 1994 |
Comparison of A4 and A2a binding sites in striatum and COS cells transfected with adenosine A2a receptors.
Topics: Adenosine; Alamethicin; Animals; Binding Sites; Cell Line; Corpus Striatum; Guanosine 5'-O-(3-Thiotriphosphate); Phenethylamines; Potassium Channels; Rats; Receptors, Purinergic P1; Temperature; Theophylline; Transfection | 1995 |
Influences of different adenosine receptor subtypes on catalepsy in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dose-Response Relationship, Drug; Drug Interactions; Mice; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents | 1993 |
Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism.
Topics: Adenosine; Animals; Arginine; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits; Theophylline; Time Factors | 1995 |
Interdependence of respiratory and cardiovascular changes induced by systemic hypoxia in the rat: the roles of adenosine.
Topics: Adenosine; Animals; Cardiovascular System; Carotid Arteries; Cerebrovascular Circulation; Hypoxia; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Respiration; Respiration, Artificial; Theophylline | 1994 |
Chronic haloperidol treatment leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum.
Topics: Adenosine; Animals; Antihypertensive Agents; Binding, Competitive; Dopamine D2 Receptor Antagonists; Haloperidol; Kinetics; Male; Membranes; Motor Activity; Neostriatum; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Purinergic P1; Salicylamides; Theophylline | 1994 |
Interaction between adenosine and GABAA receptors on hippocampal neurones.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Barium; Chloride Channels; Drug Combinations; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA; Theophylline | 1994 |
Characterization of adenosine receptors in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1994 |
Modulation of anoxic injury in CNS white matter by adenosine and interaction between adenosine and GABA.
Topics: Action Potentials; Adenosine; Animals; Brain; Drug Interactions; Female; gamma-Aminobutyric Acid; Hypoxia, Brain; Neural Conduction; Optic Nerve; Patch-Clamp Techniques; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rats; Receptors, GABA-B; Theophylline | 1994 |
Characterization of the prejunctional adenosine receptors in the rat anococcygeus muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic P1; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Modulation of adrenergic coronary vasoconstriction via ATP-sensitive potassium channel.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Coronary Circulation; Dogs; Electric Stimulation; Glyburide; Guanidines; Neuropeptide Y; Nitric Oxide; Norepinephrine; Peptide Fragments; Pinacidil; Potassium Channels; Sympathetic Nervous System; Theophylline; Vascular Resistance; Vasoconstriction | 1995 |
Noradrenaline but not dopamine involved in NMDA receptor-mediated hyperalgesia induced by theophylline in awake rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Hyperalgesia; Male; Methyltyrosines; Norepinephrine; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reserpine; Sulpiride; Theophylline; Tyrosine 3-Monooxygenase | 1994 |
Functional adenosine A1 receptors in goldfish brain: regional distribution and inhibition of K(+)-evoked glutamate release from cerebellar slices.
Topics: Adenosine; Adenylyl Cyclases; Amino Acids; Animals; Calcium; Cerebellum; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; Goldfish; In Vitro Techniques; Membranes; Potassium; Receptors, Purinergic P1; Theophylline | 1994 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; Electric Stimulation; Extracellular Space; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serum Albumin, Bovine; Theobromine; Theophylline; Verapamil; Xanthines | 1993 |
Release of adenosine by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Enkephalins; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Male; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Theophylline | 1994 |
Modulation of DNA synthesis via adenosine receptors in human epidermoid carcinoma (A431) cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Carcinoma, Squamous Cell; DNA, Neoplasm; Epidermal Growth Factor; Humans; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tumor Cells, Cultured; Xanthines | 1994 |
ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog.
Topics: Acetylcholine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Glyburide; Guanidines; Ion Channel Gating; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Role of exogenous adenosine as a modulator of theophylline toxicity.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Injections, Intravenous; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Theophylline | 1994 |
Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Aminoimidazole Carboxamide; Animals; Aspirin; Blood Physiological Phenomena; Coronary Thrombosis; Coronary Vessels; Dipyridamole; Disease Models, Animal; Dogs; Erythrocytes; Humans; Male; Plasma; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Ribonucleosides; Theophylline; Tubercidin | 1994 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart.
Topics: Adenosine; Animals; Antihypertensive Agents; Female; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Ischemia; Perfusion; Purinergic Antagonists; Rabbits; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
Effects of adenosine on atrial refractoriness and arrhythmias.
Topics: Action Potentials; Adenosine; Animals; Atrial Fibrillation; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Myocardium; Theophylline | 1994 |
[A study on the interstitial level of endogenous adenosine and its cardioprotective effect during ischemia/reperfusion in the canine heart].
Topics: Adenosine; Animals; Dipyridamole; Dogs; Female; Male; Microdialysis; Myocardial Reperfusion Injury; Myocardium; Theophylline | 1994 |
A potential role of central A1 adenosine receptors in the responses to hypothalamic stimulation in the anaesthetized cat.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Cats; Chemoreceptor Cells; Electric Stimulation; Ethanol; Hypothalamus; Phrenic Nerve; Pressoreceptors; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
Opposite effects of cyclohexyladenosine and theophylline on hypoxic damage in cultured neurons.
Topics: Adenosine; Animals; Biological Transport; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Embryo, Mammalian; Kinetics; L-Lactate Dehydrogenase; Neurons; Rats; Theophylline | 1994 |
Evidence for deactivation of both ectosolic and cytosolic 5'-nucleotidase by adenosine A1 receptor activation in the rat cardiomyocytes.
Topics: 5'-Nucleotidase; Adenosine; Animals; Cell Compartmentation; Cell Separation; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Heart; Male; Myocardium; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Theophylline; Virulence Factors, Bordetella | 1994 |
Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning.
Topics: Adenosine; Animals; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors | 1994 |
Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; MPTP Poisoning; Receptors, Purinergic P1; Theophylline; Tyrosine 3-Monooxygenase | 1994 |
N6-substituted adenosine receptor agonists. Synthesis and pharmacological activity as potent antinociceptive agents.
Topics: Adenosine; Analgesia; Analgesics; Animals; Indoles; Methylation; Mice; Molecular Structure; Nitrogen; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline | 1994 |
Adenosine acts as an endogenous activator of the cellular antioxidant defense system.
Topics: Adenosine; Adenosine Deaminase; Animals; Antioxidants; Catalase; Cell Line; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Glutathione Peroxidase; Glutathione Reductase; Humans; Kinetics; Leukemia, Basophilic, Acute; Mast-Cell Sarcoma; Myocardium; Pertussis Toxin; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Superoxide Dismutase; Theophylline; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1994 |
Adenosine receptors are not involved in theophylline-induced seizures.
Topics: Adenosine; Animals; Carbamazepine; Dipyridamole; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Receptors, Purinergic P1; Seizures; Theophylline | 1994 |
Electrophysiological effects of N6-cyclopentyl-adenosine and [-]-N6-[phenylisopropyl]-adenosine on pacemaker cells in sinoatrial node of guinea pigs.
Topics: Action Potentials; Adenosine; Animals; Electrophysiology; Female; Glyburide; Guinea Pigs; Male; Microelectrodes; Phenylisopropyladenosine; Sinoatrial Node; Theophylline | 1993 |
Identification and functional characterization of A1 and A2 adenosine receptors in the rat vas deferens: a comparison with A1 receptors in guinea pig left atrium and A2 receptors in guinea pig aorta.
Topics: Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Heart; In Vitro Techniques; Male; Norbornanes; Phenethylamines; Rats; Receptors, Purinergic P1; Theophylline; Vas Deferens; Xanthines | 1994 |
Adenosine blockade as primary therapy for ischemia-induced accelerated idioventricular rhythm: rationale and potential clinical application.
Topics: Adenosine; Aged; Arrhythmia, Sinus; Bradycardia; Female; Humans; Male; Myocardial Ischemia; Streptokinase; Tachycardia, Ventricular; Theophylline | 1994 |
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Potassium Channels; Rabbits; Tetrodotoxin; Theophylline | 1994 |
Prostaglandin F2 alpha and D2 release from primary Ito cell cultures after stimulation with noradrenaline and ATP but not adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Dinoprost; Endothelium; Kupffer Cells; Liver; Male; Norepinephrine; Prazosin; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Stimulation, Chemical; Theophylline | 1994 |
Therapeutic and diagnostic utility of adenosine during tachycardia evaluation in children.
Topics: Adenosine; Adolescent; Adult; Apnea; Arrhythmia, Sinus; Atrial Fibrillation; Atrial Function; Atrioventricular Node; Bradycardia; Child; Child, Preschool; Drug Interactions; Electrocardiography; Electrophysiology; Heart Block; Humans; Infant; Infant, Newborn; Injections, Intravenous; Tachycardia; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Ventricular; Theophylline | 1994 |
Cardiovascular effects of a non-xanthine-selective antagonist of the A1 adenosine receptor in the anaesthetised pig: pharmacological and therapeutic implications.
Topics: Adenine; Adenosine; Anesthesia; Animals; Atropine; Cardiovascular System; Coronary Vessels; Female; Heart; Male; Norbornanes; Propranolol; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Swine; Theophylline | 1994 |
Different influences of adenosine receptor agonists and antagonists on morphine antinociception in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dipyridamole; Dose-Response Relationship, Drug; Male; Mice; Morphine; Nociceptors; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Tail; Theophylline | 1994 |
Prejunctional autoinhibition of purinergic transmission in circular muscle of guinea-pig ileum; a mechanism distinct from P1-purinoceptor activation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Electrophysiology; Guinea Pigs; Ileum; Intercellular Junctions; Male; Muscle, Smooth; Neural Inhibition; Purinergic Antagonists; Purines; Receptors, Purinergic; Synaptic Transmission; Theophylline; Xanthines | 1994 |
Subtypes of purinoceptors in rat and dog urinary bladder smooth muscles.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Urinary Bladder | 1994 |
Effects of P1 and P2Y purinoceptor antagonists on endothelium-dependent and -independent relaxations of rat mesenteric artery to GTP and guanosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Guanosine; Guanosine Triphosphate; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Triazines | 1994 |
Effects of adenosine receptor agonists and antagonists on acquisition of passive avoidance learning.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Avoidance Learning; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents | 1994 |
The role of endogenous adenosine in a poststimulation increase in the acetylcholine content of a sympathetic ganglion.
Topics: Acetylcholine; Adenosine; Animals; Benzodiazepinones; Biological Transport; Cats; Dipyridamole; Electric Stimulation; Female; Male; Purinergic P1 Receptor Antagonists; Superior Cervical Ganglion; Theophylline | 1994 |
Role of endothelium-derived nitric oxide and adenosine in functional myocardial hyperemia.
Topics: Adenosine; Animals; Arginine; Coronary Circulation; Dogs; Female; Hemodynamics; Hyperemia; Male; Nitric Oxide; Nitroarginine; Theophylline; Vascular Resistance | 1994 |
Coupling of cerebral blood flow to neuronal activation: role of adenosine and nitric oxide.
Topics: Adenosine; Adenosine Deaminase; Animals; Arginine; Brain; Cerebrovascular Circulation; Male; Neurons; Nitric Oxide; Nitroarginine; Nitroprusside; Physical Stimulation; Rats; Rats, Wistar; Theophylline; Vibrissae | 1994 |
Does endogenous adenosine have a role in the cardiac responses to isoprenaline and in the rapid fade of the inotropic response of perfused heart?
Topics: Adenosine; Adenosine Deaminase; Animals; Atrial Function, Left; Atrial Function, Right; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Theophylline | 1994 |
[Lymphocytes with receptors to streptococcal polysaccharide group A in the thymus of rheumatism patients. Change in the response of normal thymocytes to adenosine, theophylline and decantate].
Topics: Adenosine; Adjuvants, Immunologic; Adolescent; Cells, Cultured; Child; Humans; Levamisole; Lymphocytes; Polysaccharides, Bacterial; Reference Values; Rheumatic Diseases; Streptococcus pyogenes; Theophylline; Thymus Gland | 1993 |
Modulation of striatal adenosine A1 and A2 receptors induces rotational behaviour in response to dopaminergic stimulation in intact rats.
Topics: Adenosine; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dopamine; Injections, Intraperitoneal; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1994 |
Functional evidence for retinal adenosine receptors.
Topics: Adenosine; Animals; Cattle; Dopamine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Receptors, Purinergic P1; Retina; Retinal Vessels; Swine; Theophylline; Vasodilation | 1994 |
Dipyridamole increases oxygen-glucose deprivation-induced injury in cortical cell culture.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dipyridamole; Glucose; Glutamates; Hypoxia, Brain; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Theophylline | 1994 |
Adenosine A1 receptor inhibition of glutamate exocytosis and protein kinase C-mediated decoupling.
Topics: 4-Aminopyridine; Adenosine; Animals; Cerebral Cortex; Enzyme Activation; Exocytosis; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Potassium Chloride; Protein Kinase C; Receptors, Purinergic; Synaptosomes; Theophylline | 1993 |
The cardiovascular effects of selective adenosine A1 and A2 receptor agonists in the pithed rat: no role for glibenclamide-sensitive potassium channels.
Topics: Adenosine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cardiovascular System; Cyclopentanes; Glyburide; Heart Rate; Male; Parasympatholytics; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Sensitivity and Specificity; Theophylline; Time Factors | 1993 |
Effect of tienoxolol, a new diuretic beta-blocking agent, on urinary prostaglandin excretion in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Antagonists; Animals; Brain Chemistry; Dinoprostone; Diuresis; Epoprostenol; Furosemide; Male; Natriuresis; Propanolamines; Prostaglandins; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1993 |
Adenosine A1 receptor-mediated inhibition of evoked glutamate release is coupled to calcium influx decrease in goldfish brain synaptosomes.
Topics: Adenosine; Amino Acids; Animals; Brain; Calcium; Calcium Channel Blockers; Fura-2; Glutamates; Glutamic Acid; Goldfish; Kinetics; omega-Conotoxins; Peptides; Phenylisopropyladenosine; Potassium; Receptors, Purinergic; Synaptosomes; Theophylline | 1993 |
High-performance liquid chromatography of the adenosine A1 agonist N6-cyclopentyladenosine and the A1 antagonist 8-cyclopentyltheophylline and its application in a pharmacokinetic study in rats.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Ligands; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1993 |
Role of adenosine in the hypoxic ventilatory response of the newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Cerebrospinal Fluid; Citrates; Dipyridamole; Drug Combinations; Hypoxia; Oxygen; Purinergic P1 Receptor Antagonists; Respiration; Swine; Theophylline | 1994 |
Extracellular adenosine concentrations in hippocampal brain slices and the tonic inhibitory modulation of evoked excitatory responses.
Topics: Action Potentials; Adenosine; Animals; Dipyridamole; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Theophylline | 1994 |
Effect of pertussis toxin treatment on the putative adenosine A3 receptor-mediated hypotensive response in the rat.
Topics: Adenosine; Adenylate Cyclase Toxin; Animals; Blood Pressure; CHO Cells; Cricetinae; Heart Rate; Male; Pertussis Toxin; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Virulence Factors, Bordetella | 1993 |
Adenosine induces contractions in suncus ileum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Ileum; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Primates; Receptors, Purinergic; Theophylline | 1993 |
Endogenous adenosine does not activate ATP-sensitive potassium channels in the hypoxic guinea pig ventricle in vivo.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Cardiac Pacing, Artificial; Cell Hypoxia; Glyburide; Guanidines; Guinea Pigs; Heart Conduction System; Myocardium; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Stereoisomerism; Theophylline | 1994 |
Involvement of adenosine in postictal events in rats given electroshock.
Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Electroshock; Female; Hindlimb; Male; Rats; Rats, Wistar; Seizures; Theophylline; Valproic Acid | 1994 |
Identification of adenosine A2 receptor-cAMP system in human aortic endothelial cells.
Topics: Acetylcholine; Adenosine; Alkynes; Animals; Antihypertensive Agents; Aorta; Aorta, Thoracic; Base Sequence; Cells, Cultured; Cyclic AMP; DNA Primers; Endothelium, Vascular; Humans; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline | 1994 |
Synergistic effects of angiotensin and adenosine in the renal microvasculature.
Topics: Adenosine; Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Drug Synergism; In Vitro Techniques; Isoquinolines; Kidney; Male; Microcirculation; Muscle, Smooth, Vascular; Purinergic P1 Receptor Antagonists; Quinapril; Rabbits; Rats; Rats, Sprague-Dawley; Renal Circulation; Saralasin; Tetrahydroisoquinolines; Theophylline; Vasoconstriction | 1994 |
A1 receptor mediated myocardial infarct size reduction by endogenous adenosine is exerted primarily during ischaemia.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phenylisopropyladenosine; Rabbits; Random Allocation; Receptors, Adrenergic, alpha-1; Theophylline; Xanthines | 1994 |
A link between adenosine, ATP-sensitive K+ channels, potassium and muscle vasodilatation in the rat in systemic hypoxia.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Hypoxia; Muscles; Potassium; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Vasodilation | 1993 |
The effect of suramin on vasodilator responses to ATP and 2-methylthio-ATP in the Sprague-Dawley rat coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Vessels; Drug Interactions; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Perfusion; Rats; Rats, Sprague-Dawley; Suramin; Theophylline; Thionucleotides; Vasodilation; Vasodilator Agents | 1994 |
Pharmacological actions of the coenzymes NAD(H) and NADP(H) on the rat anococcygeus muscle.
Topics: Adenosine; Animals; Arginine; Electric Stimulation; Male; Muscle Contraction; Muscle Relaxation; NAD; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Theophylline | 1994 |
BW-A522 blocks adenosine A3 receptor-mediated hypotensive responses in the rat.
Topics: Adenosine; Animals; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1994 |
Role of adenosine in the sympathetic activation produced by isometric exercise in humans.
Topics: Adenosine; Adult; Blood Pressure; Dose-Response Relationship, Drug; Exercise; Female; Humans; Male; Muscles; Reflex; Sympathetic Nervous System; Theophylline | 1994 |
Adenosine receptor-mediated bronchoconstriction and bronchial hyperresponsiveness in allergic rabbit model.
Topics: Adenosine; Animals; Bronchi; Bronchoconstriction; Dust; Immunization; Mites; Rabbits; Receptors, Purinergic P1; Respiratory Hypersensitivity; Theophylline; Xanthines | 1994 |
Adenosine: differential effect on blood flow to subregions of the upper gastrointestinal tract.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Duodenum; Esophagus; Gastric Fundus; Gastric Mucosa; Ileum; Inosine; Intestine, Small; Jejunum; Mucous Membrane; Muscle, Smooth; Organ Specificity; Purinergic P1 Receptor Antagonists; Pyloric Antrum; Rabbits; Receptors, Purinergic P1; Regional Blood Flow; Theophylline; Vasodilator Agents | 1994 |
Acadesine extends the window of protection afforded by ischaemic preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Theophylline; Time Factors | 1994 |
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways.
Topics: Adenosine; Animals; Bronchi; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Humans; Isoproterenol; Male; Muscle Relaxation; Nicardipine; Nifedipine; Nitroprusside; Theophylline; Trachea | 1994 |
Combined effect of adenosine, alpha adrenergic and adenosine antagonists on serum insulin and insulin secretion from rat pancreatic islets.
Topics: Adenosine; Animals; Drug Interactions; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Prazosin; Rats; Rats, Wistar; Theophylline; Xanthines; Yohimbine | 1994 |
Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Muscle Denervation; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1994 |
Effects of adenosine infusion during reperfusion after cold cardioplegic ischemia in neonatal lambs.
Topics: Adenosine; Animals; Animals, Newborn; Heart Arrest, Induced; Myocardial Contraction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Receptors, Purinergic P1; Sheep; Theophylline; Ventricular Function, Left | 1993 |
Effects of adenosine agonists and antagonists on pulmonary ventilation in conscious rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Bronchoconstriction; Bronchodilator Agents; Lung; Male; Naloxone; Narcotics; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Theophylline; Vasodilator Agents; Xanthines | 1993 |
Effect of adenosine blockade on plasma renin activity and catecholamines.
Topics: Adenosine; Animals; Blood Pressure; Caffeine; Consciousness; Epinephrine; Hydralazine; Kidney; Male; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renin; Renin-Angiotensin System; Secretory Rate; Sodium, Dietary; Theophylline; Xanthines | 1993 |
Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Exercise Test; Hemodynamics; Myocardial Ischemia; Physical Exertion; Theophylline; Vasodilation | 1993 |
Adenosine and cerebrovascular hyperemia during insulin-induced hypoglycemia in newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Arterioles; Blood Glucose; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Hyperemia; Hypoglycemia; Insulin; Muscle, Smooth, Vascular; Oxygen; Partial Pressure; Pia Mater; Regional Blood Flow; Swine; Theophylline; Vasodilation | 1993 |
Effects of inosine on adenosine-induced coronary vasodilation in the open chest dog.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Heart; Heart Conduction System; Heart Rate; Hypoxanthines; Infusions, Intra-Arterial; Inosine; Male; Myocardium; Theophylline; Vasodilation | 1993 |
Inhibition of neutrophil function in vitro by nimesulide. Preliminary evidence of an adenosine-mediated mechanism.
Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Calcium; Free Radicals; Glucuronidase; Humans; In Vitro Techniques; Luminescent Measurements; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic P1; Sulfonamides; Superoxides; Theophylline | 1993 |
Involvement of adenosine-sensitive cyclic AMP-generating systems in cobalt-induced epileptic activity in the rat.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Electroencephalography; Epilepsy; In Vitro Techniques; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Theophylline | 1993 |
Effects of adenosine on rate-dependent atrioventricular nodal function. Potential roles in tachycardia termination and physiological regulation.
Topics: Adenosine; Animals; Atrioventricular Node; Cardiac Pacing, Artificial; Disease Models, Animal; Electric Stimulation; Guinea Pigs; Heart Rate; In Vitro Techniques; Models, Cardiovascular; Perfusion; Rabbits; Tachycardia, Atrioventricular Nodal Reentry; Theophylline | 1993 |
Effects of 5'-N-ethylcarboxamideadenosine (NECA) on erythropoietin production.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Erythropoietin; Female; Hypoxia; Liver Neoplasms; Mice; Mice, Inbred Strains; Osmolar Concentration; Polycythemia; Theophylline; Tumor Cells, Cultured | 1993 |
Effects of theophylline and cyclohexyladenosine on brain injury following normo- and hyperglycemic ischemia: a histopathologic study in the rat.
Topics: Adenosine; Animals; Blood Pressure; Brain; Brain Ischemia; Hyperglycemia; Male; Osmolar Concentration; Rats; Rats, Wistar; Reference Values; Theophylline | 1994 |
The P1-purinoceptors that mediate the prejunctional inhibitory effect of adenosine on capsaicin-sensitive nonadrenergic noncholinergic neurotransmission in the rat mesenteric arterial bed are of the A1 subtype.
Topics: Adenosine; Adrenergic Fibers; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cholinergic Fibers; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Tonus; Muscle, Smooth, Vascular; Neuromuscular Junction; Rats; Rats, Wistar; Receptors, Purinergic P1; Sensitivity and Specificity; Synaptic Transmission; Theophylline; Vasodilation; Xanthines | 1993 |
Adenosine contributes to neutrophil-mediated loss of myocardial function in post-ischemic guinea-pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Cardiac Output; Coronary Circulation; Disease Models, Animal; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Neutrophils; Receptors, Purinergic P1; Theophylline; Xanthines | 1993 |
Adenosine antagonists prevent hypoxia-induced depression of excitatory but not inhibitory synaptic currents.
Topics: Adenosine; Animals; Electrophysiology; Hypoxia; In Vitro Techniques; Models, Neurological; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Theophylline; Xanthines | 1993 |
Endogenous adenosine and coronary vasoconstriction in hypoperfused myocardium during exercise.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Coronary Vessels; Dogs; Myocardial Contraction; Myocardial Ischemia; Physical Exertion; Prostaglandin Endoperoxides, Synthetic; Regional Blood Flow; Theophylline; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1993 |
Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes.
Topics: Adenosine; Animals; Carbachol; Cell Death; Cells, Cultured; Iodoacetates; Iodoacetic Acid; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Theophylline | 1993 |
Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Spatial Behavior; Theophylline | 1993 |
Ca2+ preconditioning elicits a unique protection against the Ca2+ paradox injury in rat heart. Role of adenosine. Fixed.
Topics: Adenosine; Animals; Calcium; Male; Microscopy, Electron; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Theophylline; Virulence Factors, Bordetella | 1994 |
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Humans; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Radioligand Assay; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Theophylline; Threonine; Tritium | 1994 |
Adenosine mediates hypoxic release of arginine vasopressin in fetal sheep.
Topics: Adenosine; Animals; Arginine Vasopressin; Blood Pressure; Fetus; Gases; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Papaverine; Purinergic P1 Receptor Antagonists; Sheep; Theophylline | 1994 |
Adenosine, a "retaliatory" metabolite, promotes anoxia tolerance in turtle brain.
Topics: Adenosine; Animals; Brain; Cerebellum; Hypoxia; In Vitro Techniques; Purinergic Antagonists; Theophylline; Turtles; Xanthines | 1993 |
Attenuation of potassium cyanide-mediated neuronal cell death by adenosine.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Neurons; Osmolar Concentration; Potassium Cyanide; Purinergic Antagonists; Theobromine; Theophylline | 1993 |
Covalent binding of a selective agonist irreversibly activates guinea pig coronary artery A2 adenosine receptors.
Topics: Adenosine; Animals; Blood Flow Velocity; Coronary Vessels; Guinea Pigs; Isothiocyanates; Phenethylamines; Receptors, Purinergic; Theophylline; Thiocyanates; Vasodilation | 1993 |
Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart.
Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Regional Blood Flow; Theophylline | 1993 |
Modulation of vasopressin actions on human platelets by plasma adenosine and theophylline: gender differences.
Topics: Adenosine; Adult; Arginine Vasopressin; Blood Platelets; Female; Humans; Male; Middle Aged; Platelet Aggregation; Serotonin; Sex Characteristics; Theobromine; Theophylline | 1993 |
Adenosine stimulates proliferation of human endothelial cells in culture.
Topics: Adenosine; Adenosine Deaminase; Cell Division; Cells, Cultured; Endothelium, Vascular; Humans; Purinergic Antagonists; Theophylline; Thymidine | 1993 |
Effect of adenosine on heart rate in isolated muskrat and guinea pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Arvicolinae; Guinea Pigs; Heart Rate; In Vitro Techniques; Reference Values; Theophylline; Thioinosine; Xanthines | 1993 |
Adenosine-mediated autoregulation of retinal arteriolar tone in the piglet.
Topics: Adenosine; Animals; Arterioles; Homeostasis; Microcirculation; Muscle, Smooth, Vascular; Ocular Hypotension; Oxygen Consumption; Receptors, Purinergic; Retinal Artery; Swine; Theophylline; Thioinosine; Vasodilation; Video Recording | 1993 |
Adenosine modulates reactive hyperemia in rat gut.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Blood Pressure; Hyperemia; Intestines; Lipids; Male; Mesenteric Vascular Occlusion; Micelles; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1993 |
A2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide.
Topics: Adenosine; Animals; Antihypertensive Agents; Arginine; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Prostaglandins; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1993 |
Functional characterization of three adenosine receptor types.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adipose Tissue; Animals; Aorta, Thoracic; Blood Platelets; Coronary Vessels; Dogs; Female; Guinea Pigs; Heart; Humans; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neutrophils; Norepinephrine; Phenethylamines; Rats; Receptors, Purinergic; Theophylline; Vasodilator Agents; Xanthines | 1993 |
Glucose deprivation results in a lactate preventable increase in adenosine and depression of synaptic transmission in rat hippocampal slices.
Topics: Adenosine; Animals; Cytochalasin B; Electrophysiology; Glucose; Hippocampus; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Male; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Theophylline | 1993 |
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Animals; Chloride Channels; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Membrane Proteins; Mucous Membrane; Muscle Relaxation; Muscle, Smooth; Nucleotides; Prostaglandins; Theophylline; Trachea; Uridine Triphosphate | 1993 |
Differential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neurons.
Topics: Adenosine; Animals; Calcium Channels; Cyclic AMP; Electric Conductivity; Electrophysiology; Guinea Pigs; Hippocampus; Neurons; omega-Conotoxins; Peptides, Cyclic; Protein Kinase Inhibitors; Protein Kinases; Receptors, Purinergic; Theophylline | 1993 |
The effects of the adenosine reuptake inhibitor soluflazine on synaptic potentials and population hypoxic depolarizations in area CA1 of rat hippocampus in vitro.
Topics: Adenosine; Animals; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Piperazines; Rats; Rats, Inbred F344; Synapses; Synaptic Transmission; Theophylline | 1993 |
Myocardial adenosine stimulates release of cyclic adenosine monophosphate from capillary endothelial cells in guinea pig heart.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Alprostadil; Animals; Capillaries; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Guinea Pigs; Myocardium; Oxygen; Procaterol; Quinazolines; Theophylline; Triazoles; Vasodilation | 1993 |
Efficient induction of superoxide release from human neutrophils by the galactoside-specific lectin from Viscum album.
Topics: Adenosine; Concanavalin A; Galectins; Hemagglutinins; Humans; Lectins; Male; Mistletoe; Neutrophils; Oxidation-Reduction; Plant Lectins; Plants, Medicinal; Respiratory Burst; Superoxides; Theophylline | 1993 |
Effect of adenosine receptor ligands on cAMP content in human airways and peripheral lung.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Aged; Child; Cromolyn Sodium; Cyclic AMP; Female; Humans; Ligands; Lung; Male; Middle Aged; Phenethylamines; Receptors, Purinergic; Respiratory System; Theophylline; Xanthines | 1993 |
Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Baclofen; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; Male; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic; Synapses; Theophylline | 1993 |
[Increase in erythropoietin secretion mediated by adenosine A2 receptors].
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Carcinoma, Hepatocellular; Cell Hypoxia; Cyclic AMP; Erythropoietin; Humans; Liver Neoplasms; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured | 1993 |
Role of adenosine in heterosynaptic, posttetanic depression in area CA1 of hippocampus.
Topics: Adenosine; Animals; Dendrites; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neurons, Afferent; Purinergic Antagonists; Rats; Synapses; Synaptic Transmission; Theophylline; Xanthines | 1993 |
Adenosine release is a major cause of failure of synaptic transmission during hypoglycaemia in rat hippocampal slices.
Topics: Action Potentials; Adenosine; Animals; Caffeine; Cell Hypoxia; Energy Metabolism; Evoked Potentials; Glucose; Glyburide; Hippocampus; Hypoglycemia; Neural Inhibition; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline; Tolbutamide | 1993 |
The role of adenosine in hypoxic pulmonary vasoconstriction in the anaesthetized rat.
Topics: Adenosine; Animals; Blood Pressure; Hypoxia; Lung; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Wistar; Theophylline; Unconsciousness; Vasoconstriction | 1993 |
Pertussis toxin sensitive effects of dipyridamole on rat atrial rate.
Topics: Adenosine; Animals; Atrial Function; Depression, Chemical; Dipyridamole; Drug Interactions; Female; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine; Pertussis Toxin; Rats; Rats, Wistar; Sensitivity and Specificity; Theophylline; Tritium; Virulence Factors, Bordetella | 1993 |
Myocardial adenosine, flow, and metabolism during adenosine antagonism and adrenergic stimulation.
Topics: Adenosine; Animals; Coronary Circulation; Extracellular Space; Exudates and Transudates; Guinea Pigs; Hemodynamics; In Vitro Techniques; Male; Myocardium; Norepinephrine; Perfusion; Phosphorylation; Sympathomimetics; Theophylline | 1993 |
Superoxide dismutase restores contractile and metabolic dysfunction through augmentation of adenosine release in coronary microembolization.
Topics: 5'-Nucleotidase; Adenosine; Animals; Coronary Circulation; Dogs; Embolism; Injections; Lactates; Lactic Acid; Microspheres; Myocardial Contraction; Myocardial Ischemia; Myocardium; Superoxide Dismutase; Theophylline; Time Factors; Vasodilation | 1993 |
Effects of adenosine and its analogues on actin polymerization in human polymorphonuclear leucocytes.
Topics: Actins; Adenosine; Adenosine Deaminase; Biopolymers; Complement C5a; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Platelet Activating Factor; Theophylline | 1993 |
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicuculline; Cerebral Cortex; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Seizures; Theophylline; Thioinosine | 1993 |
Higher adenosine dosage required for supraventricular tachycardia in infants treated with theophylline.
Topics: Adenosine; Apnea; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Theophylline | 1993 |
Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; In Vitro Techniques; Injections, Intra-Arterial; Male; Muscle Contraction; Myocardial Contraction; Papillary Muscles; Potassium Channels; Theophylline; Vasodilation | 1993 |
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines | 1993 |
Homologous sensitisation of embryonic chick atrial myocytes to adenosine: mediation by adenosine A1 receptor and guanine nucleotide binding protein.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Cells, Cultured; Chick Embryo; GTP-Binding Proteins; Isoproterenol; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline; Up-Regulation | 1993 |
Adenosine is a mediator of ethanol-induced gastric vasodilation in dogs.
Topics: Adenosine; Animals; Cimetidine; Dogs; Ethanol; Histamine; Indomethacin; Male; Muscle, Smooth; Purinergic Antagonists; Pyrilamine; Regional Blood Flow; Stomach; Theophylline; Vascular Resistance; Vasodilation | 1993 |
Respiratory failure following adenosine administration.
Topics: Adenosine; Contraindications; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Respiratory Insufficiency; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Theophylline | 1993 |
The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Female; Heart; Hemodynamics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Necrosis; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Risk Factors; Theophylline | 1993 |
Adenosine A2a receptor modulation of electrically evoked endogenous GABA release from slices of rat globus pallidus.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Electric Stimulation; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Time Factors; Xanthines | 1993 |
Adenosine modulation of amino acid release in rat hippocampus during ischemia and veratridine depolarization.
Topics: Adenosine; Amino Acids; Animals; Brain Ischemia; Dialysis; Hippocampus; Infusions, Parenteral; Male; Membrane Potentials; Micromanipulation; Phenylisopropyladenosine; Rats; Rats, Wistar; Theophylline; Veratridine | 1993 |
Adenosine regulates coronary blood flow during increased work and decreased supply.
Topics: Adenosine; Animals; Coronary Circulation; Dobutamine; Dogs; Female; Heart; Hemodynamics; Male; Myocardium; Physical Exertion; Theophylline | 1993 |
Differential sensitization of cardiac actions of adenosine in rats after chronic theophylline treatment.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Heart; Heart Atria; Male; Myocardium; Rats; Rats, Wistar; Receptors, Purinergic; Theophylline; Time Factors; Up-Regulation; Xanthines | 1993 |
Inhibition of human monocyte TNF production by adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Assay; Cells, Cultured; Dexamethasone; Dipyridamole; Endotoxins; Humans; L Cells; Lipopolysaccharides; Male; Mice; Monocytes; Phenylisopropyladenosine; Rats; Rats, Inbred F344; Receptors, Purinergic; Theophylline; Tumor Necrosis Factor-alpha | 1993 |
Endogenous adenosine delays the onset of hypoxic depolarization in the rat hippocampus in vitro via an action at A1 receptors.
Topics: Adenosine; Animals; Evoked Potentials; Gerbillinae; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Purinergic Antagonists; Rats; Receptors, Purinergic; Theophylline | 1993 |
Role of adenosine triphosphate and adenosine in oxygen-induced pulmonary vasodilation in fetal lambs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Female; Fetus; Oxygen; Pregnancy; Pulmonary Circulation; Purinergic Antagonists; Sheep; Theophylline; Triazines; Vascular Resistance; Vasodilation | 1993 |
Activation of adenosine receptors before ischemia enhances tolerance against myocardial stunning in the rabbit heart.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Analysis of Variance; Animals; Cardiotonic Agents; Cardiovascular Agents; Hemodynamics; Humans; Infusions, Intravenous; Isoproterenol; Lactates; Male; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Rabbits; Receptors, Purinergic P1; Theophylline | 1996 |
Hypoxia preconditions rabbit myocardium via adenosine and catecholamine release.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Catecholamines; Heart; Hemodynamics; Hypoxia; In Vitro Techniques; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phenoxybenzamine; Rabbits; Theophylline; Time Factors | 1995 |
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Antihypertensive Agents; Cyclic AMP; Humans; Middle Aged; Phenethylamines; Phenylisopropyladenosine; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purines; Receptors, Purinergic P1; Serotonin; Sulfonamides; Theophylline; Vasodilator Agents; Xanthines | 1995 |
Adenosine modulates methylmercuric chloride (MeHgCl)-induced D-aspartate release from neonatal rat primary astrocyte cultures.
Topics: Adenosine; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Cells, Cultured; Glutamic Acid; Glutathione; Methylmercury Compounds; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Tritium | 1995 |
Preconditioning in isolated superfused human muscle.
Topics: Adenosine; Animals; Atrial Function; Female; Heart; Humans; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Perfusion; Rabbits; Receptors, Purinergic P1; Theophylline | 1995 |
Vasodilatation produced by adenosine in isolated rat perfused mesenteric artery: a role for endothelium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Glyburide; Male; Mesenteric Arteries; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Suramin; Theobromine; Theophylline; Vasodilation; Vasodilator Agents | 1995 |
Hypoglycemic hyperemia in retina of newborn pigs. Involvement of adenosine.
Topics: Adenosine; Animals; Animals, Newborn; Blood Glucose; Blood Pressure; Fluorescein Angiography; Hyperemia; Hypoglycemia; Image Processing, Computer-Assisted; Injections, Intravenous; Insulin; Purinergic P1 Receptor Antagonists; Random Allocation; Regional Blood Flow; Retinal Vessels; Swine; Theophylline; Video Recording | 1996 |
A study on rats of the effects of chronic hypoxia from birth on respiratory and cardiovascular responses evoked by acute hypoxia.
Topics: Adenosine; Animals; Animals, Newborn; Blood Gas Analysis; Cardiovascular System; Hypoxia; Potassium; Rats; Rats, Wistar; Respiration; Theophylline | 1995 |
Combined inhibitory effects of ethanol and adenosine on the responses of rabbit platelets to thrombin.
Topics: Adenosine; Animals; Blood Platelets; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline; Thrombin | 1995 |
Brain tissue hydrolysate acts on presynaptic adenosine receptors in the rat hippocampus.
Topics: Adenosine; Amino Acids; Animals; Hippocampus; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Time Factors | 1995 |
Adenosine mediates metabolic and cardiovascular responses to hypoxia in fetal sheep.
Topics: Acidosis; Adenosine; Animals; Blood Pressure; Female; Fetus; Glycolysis; Heart Rate; Hypoxia; Pregnancy; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Tromethamine | 1995 |
Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway.
Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Caffeine; Dopamine Agonists; Ergolines; Genes, fos; Globus Pallidus; Immunohistochemistry; Male; Neostriatum; Neural Pathways; Phosphodiesterase Inhibitors; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reserpine; Theobromine; Theophylline | 1995 |
Pharmacological activities of imidazo[1,2-alpha]pyrazine derivatives.
Topics: Adenosine; Animals; Calcium; Cardiovascular Agents; Cattle; Diuresis; Guinea Pigs; Heart Atria; Heart Rate; Ileum; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Phosphodiesterase Inhibitors; Pyrazines; Rabbits; Rats; Rats, Wistar; Theophylline; Trachea | 1995 |
The role of adenosine in the hypotensive actions of morphine.
Topics: Adenosine; Animals; Blood Pressure; Female; Guanethidine; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1995 |
Adenosine A2 receptor-mediated stimulation of cyclic AMP in cultured chicken pineal cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Kinetics; Pineal Gland; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
Role of K+ ATP channels and adenosine in the regulation of coronary blood flow during exercise with normal and restricted coronary blood flow.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Glyburide; Guanidines; Hemodynamics; Myocardial Contraction; Physical Exertion; Pinacidil; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents | 1996 |
Theophylline increases coronary vascular tone in humans: evidence for a role of endogenous adenosine in flow regulation.
Topics: Adenosine; Adult; Blood Pressure; Coronary Circulation; Coronary Vessels; Female; Heart Rate; Humans; Hypoxia; Male; Myocardium; Oxygen; Oxygen Consumption; Oxyhemoglobins; Physical Exertion; Purinergic P1 Receptor Antagonists; Respiration; Theophylline; Vasodilator Agents | 1995 |
Purine suppression of proliferation of Sertoli-like TM4 cells in culture.
Topics: Adenosine; Animals; Caffeine; Cell Division; Cells, Cultured; Male; Mice; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1; Sertoli Cells; Theobromine; Theophylline | 1995 |
Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor.
Topics: Adenosine; Animals; Arterioles; Cricetinae; Iodine Radioisotopes; Iodobenzenes; Male; Mast Cells; Mesocricetus; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasomotor System; Xanthines | 1996 |
Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization.
Topics: Actin Cytoskeleton; Actins; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Biological Factors; Blood Platelets; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytochalasin B; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Receptors, Purinergic P1; Respiratory Burst; Theophylline | 1996 |
Action of adenosine receptor antagonists on hypoxia-induced effects in the rat hippocampus in vitro.
Topics: Adenosine; Animals; Corpus Striatum; Dizocilpine Maleate; Hypoxia; Male; Membrane Potentials; Microelectrodes; Neuroglia; Neuroprotective Agents; Phosphodiesterase Inhibitors; Potassium; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1995 |
Anxiolytic activity of adenosine receptor activation in mice.
Topics: Adenosine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Male; Maze Learning; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
Adenosine in acute theophylline intoxication.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Bronchodilator Agents; Drug Interactions; Humans; Theophylline | 1995 |
The involvement of ATP-sensitive potassium channels and adenosine in the regulation of coronary flow in the isolated perfused rat heart.
Topics: Adenosine; Adenosine Triphosphate; Animals; Benzopyrans; Coronary Circulation; Cromakalim; Glyburide; Heart; In Vitro Techniques; Male; Perfusion; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Theophylline; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Enhancement of myocardial reactive hyperemia with manganese-superoxide dismutase: role of endothelium-derived nitric oxide.
Topics: Adenosine; Animals; Arginine; Catalase; Dogs; Female; Male; Manganese; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Reactive Oxygen Species; Superoxide Dismutase; Theophylline; Time Factors | 1996 |
A novel irreversible antagonist of the A1-adenosine receptor.
Topics: Adenosine; Animals; Carbachol; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
Interstitial adenosine and function in rat heart in vivo: effects of adrenaline and 8-cyclopentyl-1,3-dimethylxanthine.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Epinephrine; Extracellular Space; Heart Ventricles; In Vitro Techniques; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Ventricular Function, Left | 1996 |
Role of adenosine in the renal responses to contrast medium.
Topics: Adenosine; Animals; Calcium Channel Blockers; Contrast Media; Diltiazem; Dogs; Glomerular Filtration Rate; Humans; Iohexol; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Radiography; Receptors, Purinergic P1; Renal Circulation; Renal Plasma Flow, Effective; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Effects of adenosine analogues on apomorphine-induced penile erection in rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Male; Penile Erection; Rats; Receptors, Purinergic P1; Theophylline | 1995 |
Role of nitric oxide, adenosine, N-methyl-D-aspartate receptors, and neuronal activation in hypoxia-induced pial arteriolar dilation in rats.
Topics: Adenosine; Animals; Arginine; Arterioles; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hypoxia, Brain; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pia Mater; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Theophylline; Vasodilation | 1995 |
Simultaneous measurement of cyclopentyladenosine-induced contraction and intracellular calcium in bronchial rings from allergic rabbits and it's antagonism.
Topics: Adenosine; Animals; Bronchi; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth; Rabbits; Theophylline | 1996 |
Modulation of the hyperpolarization-activated current (I(f)) by adenosine in rabbit sinoatrial myocytes.
Topics: Acetylcholine; Action Potentials; Adenosine; Analysis of Variance; Animals; Barium Compounds; Cells, Cultured; Chlorides; Egtazic Acid; Heart Conduction System; Manganese Compounds; Membrane Potentials; Models, Cardiovascular; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Sinoatrial Node; Theophylline | 1996 |
Role of adenosine in regulation of coronary flow in dogs with inhibited synthesis of endothelium-derived nitric oxide.
Topics: Adenosine; Animals; Atrial Function; Cardiac Pacing, Artificial; Coronary Circulation; Dogs; Endothelium, Vascular; Gases; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Lactic Acid; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Theophylline | 1996 |
Quantitative relation between interstitial adenosine concentration and coronary blood flow.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Models, Cardiovascular; Osmolar Concentration; Theophylline | 1996 |
An adenosine agonist increases blood flow and density of capillary branches in the optic tectum of Xenopus laevis tadpoles.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Capillaries; Microcirculation; Microscopy, Video; Neovascularization, Physiologic; Nitroglycerin; Regional Blood Flow; Superior Colliculi; Theophylline; Time Factors; Vasodilator Agents; Xenopus laevis | 1994 |
Regulation of rhythmic movements by purinergic neurotransmitters in frog embryos.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Culture Techniques; Embryo, Nonmammalian; Glutamic Acid; Ion Channel Gating; Motor Neurons; Movement; N-Methylaspartate; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spinal Cord; Suramin; Swimming; Synapses; Theophylline; Xenopus | 1996 |
Adenosine transport inhibitors enhance high K(+)-evoked taurine release from rat hippocampus.
Topics: Adenosine; Animals; Biological Transport; Calcium; Cortical Spreading Depression; Dipyridamole; Glutamic Acid; Hippocampus; Male; Microdialysis; Potassium; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Taurine; Theophylline; Thioinosine | 1996 |
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae.
Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Muscle, Smooth; Rats; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
A biphasic response to adenosine in the coronary vasculature of the K(+)-arrested perfused rat heart.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Heart; Heart Arrest, Induced; In Vitro Techniques; Male; Muscle Relaxation; Perfusion; Potassium; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Theophylline; Vasodilator Agents | 1996 |
Activation of multiple sites by adenosine analogues in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Sulfonamides; Theophylline; Triazines; Triazoles; Xanthines | 1996 |
Branchial and systemic roles of adenosine receptors in rainbow trout: an in vivo microscopy study.
Topics: Adenosine; Animals; Blood Circulation; Branchial Region; Female; Male; Oncorhynchus mykiss; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilator Agents | 1996 |
Adrenergic activation confers cardioprotection mediated by adenosine, but is not required for ischemic preconditioning.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Norepinephrine; Phentolamine; Prazosin; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Theophylline; Tyramine | 1996 |
Chronic exposure to adenosine receptor agonists and antagonists reciprocally regulates the A1 adenosine receptor-adenylyl cyclase system in cerebellar granule cells.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cerebellum; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 1996 |
The role of adenosine receptors in the rostral ventrolateral medulla in the cardiovascular response to defence area stimulation in the rat.
Topics: Adenosine; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Defense Mechanisms; Electric Stimulation; Heart Rate; Hypothalamus; Male; Medulla Oblongata; Microinjections; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regional Blood Flow; Theophylline | 1996 |
Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth-promoting effect of myenteric plexus explants.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Aminohydrolases; Animals; Cells, Cultured; Colforsin; Drug Interactions; Fibroblast Growth Factors; Fibronectins; Gangliosides; Guanosine Triphosphate; Laminin; Myenteric Plexus; Neostriatum; Nerve Growth Factors; Neurites; Neurons; Neuropeptides; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin; Theophylline | 1996 |
Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia.
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypoxia; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline; Vasodilation | 1996 |
Altered sensory behaviors in mice following manipulation of endogenous spinal adenosine neurotransmission.
Topics: Adenosine; Animals; Deoxyadenosines; Grooming; Male; Mice; Neurotransmitter Agents; Pain; Spinal Cord; Substance P; Theophylline | 1996 |
Metabolic effects of ischemic preconditioning and adenosine receptor blockade in dogs.
Topics: Adenosine; Animals; Creatine; Dogs; Female; Lactic Acid; Male; Myocardial Ischemia; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasodilator Agents | 1996 |
Ischemia and reperfusion injury of the human colon and ileum.
Topics: Adenosine; Allopurinol; Biomarkers; Colon; Glutathione; Humans; Ileum; Insulin; Intestinal Mucosa; Membrane Potentials; Muscle, Smooth; Organ Preservation; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Theophylline; Transplantation, Homologous | 1996 |
Differential antagonism of cardiac actions of adenosine by theophylline.
Topics: Adenosine; Adult; Aged; Animals; Binding, Competitive; Coronary Circulation; Endothelium, Vascular; Female; Guinea Pigs; Heart; Heart Conduction System; Humans; Male; Middle Aged; Perfusion; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1996 |
Release of adenosine from human sensitized lung fragments and its effect on antigen-induced mediator release.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens; Guinea Pigs; Histamine Release; Humans; Immunization; In Vitro Techniques; Leukotrienes; Lung; Mast Cells; Theophylline | 1996 |
Ethanol-induced alterations in beta-endorphin levels in specific rat brain regions: modulation by adenosine agonist and antagonist.
Topics: Adenosine; Animals; beta-Endorphin; Drug Interactions; Ethanol; Frontal Lobe; Hippocampus; Hypothalamus; Injections, Intraperitoneal; Male; Mesencephalon; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Theophylline | 1995 |
Effect of temperature on myocardial infarction in swine.
Topics: Adenosine; Adenosine Deaminase; Animals; Body Temperature; Coronary Circulation; Female; Heart; Hemodynamics; Male; Myocardial Infarction; Theophylline | 1996 |
Integration of vascular, contractile and metabolic responses to hypoxia: effects of maturation and adenosine.
Topics: Adenosine; Aging; Animals; Coronary Circulation; Coronary Vessels; Energy Metabolism; Heart; Hemodynamics; Hypoxia; In Vitro Techniques; Myocardial Contraction; Myocardium; Rabbits; Theophylline | 1996 |
Role of nitric oxide, cyclic nucleotides, and the activation of ATP-sensitive K+ channels in the contribution of adenosine to hypoxia-induced pial artery dilation.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Arteries; Blood Pressure; Cyclic AMP; Cyclic GMP; Enkephalin, Leucine; Enkephalin, Methionine; Female; Glyburide; Hypoxia; Male; Nitric Oxide; Nucleotides, Cyclic; Pia Mater; Potassium Channels; Swine; Theophylline; Vasodilation; Vasodilator Agents | 1997 |
Effect of buflomedil on the neutrophil-endothelial cell interaction under inflammatory and hypoxia conditions.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Cell Adhesion; Cell Hypoxia; Cells, Cultured; Cytokines; Endothelium, Vascular; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1; Neutrophils; P-Selectin; Pyrrolidines; Theophylline; Umbilical Veins | 1996 |
Adenosine modulates endothelin-induced bronchoconstriction in guinea pig airway.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Bronchoconstriction; Drug Synergism; Endothelin-1; Endothelin-3; Guinea Pigs; Histamine; Male; Muscle, Smooth; Respiratory System; Theophylline; Vasodilator Agents | 1997 |
Interplay between milrinone and adenosine in the inhibition of human platelet response.
Topics: Adenosine; Adenosine Diphosphate; Adult; Blood Platelets; Collagen; Cyclic AMP; Dipyridamole; Epinephrine; Humans; In Vitro Techniques; Male; Milrinone; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridones; Theophylline | 1996 |
The contribution of adenosine to paired-pulse inhibition in the normal and disinhibited hippocampal slice.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Central Nervous System Stimulants; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline | 1996 |
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Catecholamines; Corpus Striatum; Hippocampus; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Xanthines | 1997 |
Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection.
Topics: Adenosine; Animals; Female; Heart; Hemodynamics; Hypoxanthines; In Vitro Techniques; Inosine; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rabbits; Receptors, Purinergic P1; Theophylline | 1996 |
Suppressive action of endogenous adenosine on ovine fetal nonshivering thermogenesis.
Topics: Adenosine; Animals; Body Temperature; Female; Glycerol; Pregnancy; Sheep; Theophylline | 1996 |
The role of the A(2A) adenosine receptor subtype in functional hyperaemia in the hindlimb of anaesthetized cats.
Topics: Adenosine; Animals; Arteries; Cats; Gases; Hindlimb; Hydrogen-Ion Concentration; Hyperemia; Isometric Contraction; Male; Muscles; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Regional Blood Flow; Theophylline; Triazines; Triazoles | 1996 |
Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine.
Topics: 2-Chloroadenosine; Adenosine; Aging; Animals; Animals, Newborn; Cardiovascular System; Hypoxia; Respiration; Swine; Theophylline | 1996 |
Role of adenosine receptor subtypes in neural stunning of sympathetic coronary innervation.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Male; Myocardial Stunning; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sympathetic Nervous System; Theobromine; Theophylline; Vasoconstriction; Xanthines | 1997 |
A role for adenosine in metabolic depression in the marine invertebrate Sipunculus nudus.
Topics: Adenosine; Animals; Hypercapnia; Hypoxia; Nematoda; Nerve Tissue; Neurotransmitter Agents; Oxygen Consumption; Sodium Chloride; Theophylline | 1997 |
Adenosine receptor blockade enhance glycolysis in hypoperfused guinea-pig myocardium.
Topics: Adenosine; Animals; Enzyme Activation; Glucose; Glycogen; Glycolysis; Guinea Pigs; In Vitro Techniques; Lactic Acid; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Perfusion; Phosphofructokinase-1; Purinergic P1 Receptor Antagonists; Theophylline; Ventricular Function, Left | 1997 |
The action of ATP on the hepatic arterial and portal venous vascular networks of the rabbit liver: the role of adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Hepatic Artery; Liver; Liver Circulation; Perfusion; Portal Vein; Rabbits; Theophylline; Vasoconstriction; Vasodilation | 1997 |
Adenosine release mediates cyanide-induced suppression of CA1 neuronal activity.
Topics: Adenosine; Animals; Dipyridamole; Evoked Potentials; Excitatory Postsynaptic Potentials; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Cyanide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Theophylline; Xanthines | 1997 |
Adenosine activates mesangial cell proliferation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; Glomerular Mesangium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Thymidine; Xanthines | 1997 |
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Coronary Circulation; Cyclic GMP; Cyclooxygenase Inhibitors; Electrocardiography; Endothelins; Epoprostenol; Guinea Pigs; Hyperemia; In Vitro Techniques; Indomethacin; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Prostaglandin Antagonists; Purinergic P1 Receptor Antagonists; Purines; Theophylline | 1996 |
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1997 |
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs; Enzyme Activation; Enzyme Inhibitors; Infusions, Intra-Arterial; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Pyrazines; Quinolines; Receptors, Purinergic P1; Theophylline | 1997 |
Protection against global ischemia in the rabbit isolated heart 24 hours after transient adenosine A1 receptor activation.
Topics: Adenosine; Animals; Blood Pressure; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 1997 |
The effect of age on adenosine A1 receptor function in the rat heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Carbachol; Cardiovascular Agents; Cell Membrane; Colforsin; Heart; Isoproterenol; Male; Muscarinic Agonists; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sulfonic Acids; Theophylline | 1997 |
Endogenous adenosine on membrane properties of CA1 neurons in rat hippocampal slices during normoxia and hypoxia.
Topics: Adenosine; Adenosine Deaminase; Animals; Electric Stimulation; Hippocampus; Hypoxia; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Theophylline | 1997 |
Role of adenosine in the ethanol-induced potentiation of the effects of general anesthetics in rats.
Topics: Acetic Acid; Adenosine; Anesthetics, Inhalation; Animals; Drug Synergism; Ethanol; Ethers; Isoflurane; Male; Methyl Ethers; Pulmonary Alveoli; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sevoflurane; Theophylline | 1997 |
Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses.
Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Glipizide; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Theophylline; Tolbutamide; Xanthines | 1997 |
Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence.
Topics: Adenosine; Animals; Coronary Disease; Dogs; Glucose; Glycolysis; Hemodynamics; Iodoacetates; Iodoacetic Acid; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Theophylline | 1997 |
Purine nucleotides contribute to pulmonary vasodilation caused by birth-related stimuli in the ovine fetus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Gas Analysis; Erythrocytes; Female; Hydrogen-Ion Concentration; Labor, Obstetric; Oxygen; Pregnancy; Pulmonary Circulation; Purine Nucleotides; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Respiration; Sheep; Theophylline; Triazines; Vasodilation | 1997 |
Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia.
Topics: Adenosine; Analysis of Variance; Animals; Cell Membrane; Coronary Vessels; Female; Heart; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Radioligand Assay; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Theophylline; Vascular Resistance | 1997 |
Inadequate quality of a blood collection tube containing an anticoagulant/platelet inhibitor mixture.
Topics: Adenosine; Anticoagulants; Blood Specimen Collection; Dipyridamole; Equipment and Supplies; Humans; Platelet Aggregation Inhibitors; Quality Control; Theophylline | 1997 |
Evidence that adenosine contributes to maintenance of hepatosplanchnic blood flow during peritoneal sepsis in rats.
Topics: Adenosine; Animals; Liver Circulation; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sepsis; Splanchnic Circulation; Theophylline | 1997 |
A role for adenosine A2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adenosine; Animals; Hippocampus; Long-Term Potentiation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1997 |
Roles of nitric oxide and adenosine in the regulation of coronary conductance in the basal state and during reactive hyperemia.
Topics: Adenosine; Animals; Coronary Circulation; Enzyme Inhibitors; Hyperemia; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline; Vascular Resistance | 1997 |
The roles of adenosine in regulating the respiratory and cardiovascular systems in chronically hypoxic, adult rats.
Topics: Adenosine; Animals; Blood Gas Analysis; Cerebrovascular Circulation; Hemodynamics; Hindlimb; Hypoxia; Male; Potassium; Rats; Rats, Wistar; Regional Blood Flow; Respiratory Function Tests; Respiratory Mechanics; Theophylline; Vascular Resistance | 1997 |
Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo.
Topics: Adenosine; Administration, Cutaneous; Animals; Blood Proteins; Cell Degranulation; Cyproheptadine; Dinitrophenols; Female; Humans; In Vitro Techniques; Injections, Intravenous; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Pleura; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Serotonin Antagonists; Serum Albumin; Skin; Theophylline; Triazoles; Xanthines | 1997 |
Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1997 |
Adenosine modulates inspiratory neurons and the respiratory pattern in the brainstem of neonatal rats.
Topics: Adenosine; Animals; Animals, Newborn; Brain Stem; Dipyridamole; In Vitro Techniques; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Spinal Cord; Theophylline | 1997 |
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antagonists; Haloperidol; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Scopolamine; Theobromine; Theophylline; Xanthines | 1997 |
Prevention of radiocontrast-induced nephropathy by adenosine antagonists in rats with chronic nitric oxide deficiency.
Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Contrast Media; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1997 |
Intermittent ischemia: energy metabolism, cellular volume regulation, adenosine and insights into preconditioning.
Topics: Adenosine; Animals; Cell Size; Creatine; Energy Metabolism; Glyburide; Glycogen; Glycolysis; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Perfusion; Phosphorus; Phosphorylation; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Rational design of allosteric ribozymes.
Topics: Adenosine; Adenosine Triphosphate; Allosteric Regulation; Base Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genetic Engineering; Kinetics; Molecular Sequence Data; Mutation; Nucleotides; Polymerase Chain Reaction; RNA; RNA, Catalytic; Theophylline | 1997 |
Adenosine stimulates nitric oxide synthesis in rat cardiac myocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Dactinomycin; Enzyme Inhibitors; Heart; Humans; Interleukin-1; Isoproterenol; Myocardium; Naphthalenes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Stereoisomerism; Theophylline; Xanthines | 1997 |
Adenosine receptor agents and conditioned place preference.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1997 |
Adenosine depresses transmitter release but is not the basis for 'tetanic fade' at the neuromuscular junction of the rat.
Topics: Adenosine; Animals; Diaphragm; Electric Stimulation; Feedback; Female; In Vitro Techniques; Motor Endplate; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Theophylline; Xanthines | 1997 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Enzyme Inhibitors; Hippocampus; Neurons; Neurotoxins; Nitric Oxide; Organ Culture Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1997 |
Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Animals; Antihypertensive Agents; Carbon Monoxide; Dipyridamole; Diuretics; Drug Synergism; Enzyme Inhibitors; Erythropoietin; Gene Expression; Hypoxia; Kidney; Male; Oxygen; Phenethylamines; Phosphodiesterase Inhibitors; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Oxygen-induced pulmonary vasodilation is mediated by adenosine triphosphate in newborn lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Nitroarginine; Oxygen; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Purinergic Antagonists; Sheep; Theophylline; Thromboxane A2; Triazines; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1997 |
Role of adenosine in the hypoxic induction of vascular endothelial growth factor in porcine brain derived microvascular endothelial cells.
Topics: Adenosine; Animals; Brain; Capillaries; Cell Hypoxia; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Gene Expression Regulation; Lymphokines; Protein Biosynthesis; Purinergic P1 Receptor Antagonists; RNA, Messenger; Swine; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Role of adenosine in norepinephrine-induced coronary vasodilation.
Topics: Adenosine; Animals; Arteries; Coronary Circulation; Coronary Vessels; Dogs; Male; Myocardium; Norepinephrine; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilation; Veins | 1997 |
Efficacy of enalapril after ineffective theophylline treatment on erythrocytosis after renal transplantation.
Topics: Adenosine; Adult; Angiotensin-Converting Enzyme Inhibitors; Enalapril; Erythropoietin; Humans; Kidney Transplantation; Male; Polycythemia; Postoperative Complications; Theophylline | 1997 |
Myocardial infarction related atrial fibrillation: role of endogenous adenosine.
Topics: Adenosine; Aged; Atrial Fibrillation; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1997 |
Intrathecal adenosine analog administration reduces substance P in cerebrospinal fluid along with behavioral effects that suggest antinociception in rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesia; Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Injections, Spinal; Male; Motor Activity; Pain Threshold; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Substance P; Theophylline | 1997 |
[The protective action of adenosine in the development of the "calcium paradox" in the isolated heart].
Topics: Adenosine; Animals; Calcium; Cardiovascular Agents; Dipyridamole; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Myocardial Reperfusion; Myocardium; Myoglobin; Perfusion; Rats; Theophylline | 1997 |
Dilazep, an antiplatelet agent, inhibits tissue factor expression in endothelial cells and monocytes.
Topics: Adenosine; Dilazep; Endothelium, Vascular; Gene Expression; Humans; Monocytes; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Tetradecanoylphorbol Acetate; Theophylline; Thrombin; Thromboplastin; Tumor Necrosis Factor-alpha | 1997 |
Influence of adenosine, dipyridamole, adenosine antagonists and antiepileptic drugs on EEG after discharge following cortical stimulation.
Topics: Adenosine; Aminophylline; Animals; Anticonvulsants; Cerebral Cortex; Dipyridamole; Electric Stimulation; Electroencephalography; Female; Male; Rats; Rats, Wistar; Seizures; Theophylline | 1997 |
Characterization of adenosine receptors mediating spinal sensory transmission related to nociceptive information in the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Dose-Response Relationship, Drug; Female; Male; Pain; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex, Monosynaptic; Spinal Cord; Theophylline | 1997 |
Effect of adenosine and histamine receptor stimulation on canine histamine release to pentagastrin.
Topics: Adenosine; Animals; Dimaprit; Disease Models, Animal; Dogs; Female; Gas Chromatography-Mass Spectrometry; Gastric Mucosa; Histamine Agonists; Histamine Antagonists; Histamine Release; Male; Methylhistamines; Multivariate Analysis; Pentagastrin; Piperidines; Receptors, Histamine; Reference Values; Regional Blood Flow; Statistics, Nonparametric; Theophylline | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Effect of adenosine on the ouabain-insensitive Na+-ATPase activity from basolateral membrane of the proximal tubule.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cation Transport Proteins; Cell Membrane; Cholera Toxin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Furosemide; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Ouabain; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Sodium-Potassium-Exchanging ATPase; Swine; Theophylline | 1997 |
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenethylamines; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Vasodilator Agents | 1997 |
Modulation of lithium-pilocarpine-induced status epilepticus by adenosinergic agents.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Carbamazepine; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Theophylline; Vasodilator Agents | 1997 |
Importance of endogenous adenosine during ischemia and reperfusion in neonatal porcine hearts.
Topics: Adenosine; Animals; Animals, Newborn; Creatine Kinase; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Piperazines; Swine; Theophylline | 1997 |
[Effects of adenosine on cochlear function in guinea pigs].
Topics: Adenosine; Animals; Cochlea; Cochlear Microphonic Potentials; Dipyridamole; Female; Guinea Pigs; Male; Theophylline | 1996 |
Use of a newly developed technique to isolate rat pinealocytes and study the effects of adenosine agonists on melatonin production.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Separation; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Phenethylamines; Pineal Gland; Radioimmunoassay; Rats; Rats, Wistar; Theophylline | 1997 |
Congenital erythropoietin-dependent erythrocytosis responsive to theophylline treatment.
Topics: Adenosine; Adolescent; Erythropoiesis; Erythropoietin; Female; Humans; Polycythemia; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Transferrin; Second Messenger Systems; Theophylline | 1998 |
Adenosine-induced relaxation of cultured bovine retinal pericytes.
Topics: Adenosine; Animals; Capillaries; Cattle; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Purinergic P1 Receptor Antagonists; Pyrazines; Receptors, Purinergic P1; Retinal Vessels; Theophylline; Vasodilator Agents; Xanthines | 1997 |
Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Arrhythmia Agents; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation; Vasodilator Agents | 1997 |
Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets.
Topics: Adenosine; Adenosine Triphosphate; Administration, Topical; Analysis of Variance; Animals; Arterioles; Brain; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Female; Glyburide; Hypercapnia; Hypoglycemic Agents; Hypoxia; Injections, Intravenous; Intracranial Hypertension; Male; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Reperfusion; Swine; Theophylline; Vasodilation; Vasodilator Agents | 1998 |
Non-selective effects of adenosine A1 receptor ligands on energy metabolism and macromolecular biosynthesis in cultured central neurons.
Topics: Adenosine; Adenylyl Cyclases; Animals; Biological Transport; Cell Survival; Cells, Cultured; Cyclic AMP; Deoxyglucose; Embryo, Mammalian; Energy Metabolism; Female; Kinetics; Leucine; Ligands; Neurons; Prosencephalon; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA; Theophylline; Uridine | 1998 |
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline | 1998 |
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
Adenosine modulates hypoxia-induced responses in rat PC12 cells via the A2A receptor.
Topics: Adenosine; Adenosine Deaminase; Adrenal Gland Neoplasms; Animals; Calcium; Cell Hypoxia; Fluorescent Dyes; Fura-2; Lung; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pheochromocytoma; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Transcription, Genetic; Triazines; Triazoles | 1998 |
Inhibitory effects of hypoxia and adenosine on N-methyl-D-aspartate-induced pial arteriolar dilation in piglets.
Topics: Adenosine; Animals; Animals, Newborn; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Female; Hypoxia; Immunohistochemistry; Male; N-Methylaspartate; Nitric Oxide; Nitroprusside; Pia Mater; Receptors, N-Methyl-D-Aspartate; Swine; Theophylline; Vasodilator Agents | 1998 |
Effect of aging on A1-adenosine receptor-mediated inhibition of norepinephrine release in the rat heart.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Heart; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Synaptosomes; Theophylline | 1998 |
Low concentrations of adenosine receptor blocker decrease protection by hypoxic preconditioning in ischemic rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Creatine Kinase; Hypoxia; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Reperfusion Injury; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Ventricular Function, Left | 1998 |
ATP and glutamate are released from separate neurones in the rat medial habenula nucleus: frequency dependence and adenosine-mediated inhibition of release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Aniline Compounds; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Habenula; Male; Neurons; Nucleotidases; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, Purinergic P1; Suramin; Synaptic Transmission; Synaptic Vesicles; Theophylline | 1998 |
Spinal R-phenyl-isopropyl adenosine inhibits spinal dorsal horn neurons responding to noxious heat stimulation in the absence and presence of sensitization.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Hot Temperature; Male; Mustard Plant; Neurons, Afferent; Nociceptors; Pain Threshold; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley; Spinal Cord; Theophylline; Vasodilator Agents | 1998 |
Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs.
Topics: Adenosine; Animals; Antibodies, Monoclonal; Blood Platelets; Cell Adhesion; Coronary Circulation; Coronary Thrombosis; Dogs; Female; Male; Neutrophils; P-Selectin; Platelet Adhesiveness; Purinergic P1 Receptor Antagonists; Theophylline; Thromboembolism | 1998 |
Mitogenic action of adenosine on osteoblast-like cells, MC3T3-E1.
Topics: Adenosine; Animals; Becaplermin; Calcium; Cell Division; Cell Line; Dipyridamole; DNA; Humans; Kinetics; Mice; Osteoblasts; Pertussis Toxin; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Purinergic P1 Receptor Antagonists; Theophylline; Thymidine; Virulence Factors, Bordetella | 1998 |
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation | 1998 |
Effects of adenosine on cholinergic transmission in mammalian vesical parasympathetic ganglia.
Topics: Adenosine; Animals; Cats; Excitatory Postsynaptic Potentials; Female; Ganglia, Parasympathetic; Hexamethonium; Hypogastric Plexus; In Vitro Techniques; Male; Nicotinic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Synaptic Transmission; Theophylline | 1997 |
Antagonism of an adenosine/ATP receptor in follicular Xenopus oocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Oocytes; Potassium Channels; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Xenopus laevis | 1998 |
Influence of chronic nitric oxide inhibition of coronary blood flow regulation: a study of the role of endogenous adenosine in anesthetized, open-chested dogs.
Topics: Acetylcholine; Adenosine; Anesthesia, General; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Theophylline; Time Factors; Vasodilator Agents; Ventricular Function, Left | 1998 |
Adenosine acts by A1 receptors to stimulate release of prolactin from anterior-pituitaries in vitro.
Topics: Adenosine; Animals; Follicle Stimulating Hormone; In Vitro Techniques; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Prolactin; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline | 1998 |
Cyclopentyladenosine-induced homologous down-regulation of A1 adenosine receptors (A1AR) in intact neurons is accompanied by receptor sequestration but not a reduction in A1AR mRNA expression or G protein alpha-subunit content.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Cerebellum; Down-Regulation; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Neurons; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Tritium; Xanthines | 1998 |
On the mechanisms of adenosine induced pulmonary vasoconstriction in rats.
Topics: Adenosine; Adrenergic Antagonists; Animals; Cyclooxygenase Inhibitors; Cyproheptadine; Dihydroergotoxine; Endothelium, Vascular; Female; Flavonoids; Ginkgo biloba; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Plant Extracts; Platelet Activating Factor; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Quinidine; Rats; Rats, Sprague-Dawley; Theophylline; Vasoconstriction | 1997 |
Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation.
Topics: Adenosine; Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hindlimb; Hyperesthesia; Male; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Theophylline | 1998 |
Exogenous adenosine potentiates hypnosis induced by intravenous anaesthetics.
Topics: 2-Chloroadenosine; Adenosine; Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Dipyridamole; Drug Synergism; Female; Male; Mice; Midazolam; Propofol; Reflex; Sleep; Theophylline; Thiopental | 1998 |
Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation.
Topics: Adenosine; Animals; Atropine; Brain Mapping; Carbachol; Infusions, Parenteral; Male; Microinjections; Muscarinic Antagonists; Pons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Reticular Formation; Sleep; Sleep, REM; Theophylline; Time Factors; Wakefulness | 1998 |
Rapid temperature changes induce adenosine-mediated depression of synaptic transmission in hippocampal slices from rats (non-hibernators) but not in slices from golden hamsters (hibernators).
Topics: Acclimatization; Adenosine; Animals; Cricetinae; Hibernation; Hippocampus; In Vitro Techniques; Mesocricetus; Pyramidal Cells; Rats; Rats, Wistar; Species Specificity; Synaptic Transmission; Temperature; Theophylline | 1998 |
Adenosine is worth trying in patients with paroxysmal supraventricular tachycardia on chronic theophylline medication.
Topics: Adenosine; Aged; Bronchodilator Agents; Drug Interactions; Humans; Lung Diseases, Obstructive; Male; Pneumothorax; Receptors, Purinergic P1; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Paroxysmal; Theophylline; Up-Regulation | 1998 |
Adenosine and adenosine antagonism in asthma.
Topics: Adenosine; Anti-Asthmatic Agents; Humans; Theophylline; Xanthines | 1998 |
Theophylline dilates rat diaphragm arterioles via the prostaglandins pathway.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Diaphragm; Male; Nitric Oxide; Prostaglandins; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Vasodilator Agents; Xanthines | 1998 |
Effect of exogenous adenosine and its monophosphate on the contractile response to acetylcholine in the human isolated detrusor muscle strips.
Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Dipyridamole; Drug Interactions; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Theophylline; Vasodilator Agents | 1998 |
[Measurement of coronary flow reserve using adenosine 5'-triphosphate in dogs].
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Papaverine; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents | 1998 |
Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures.
Topics: Adenosine; Adenosine Kinase; Animals; Cell Hypoxia; Cells, Cultured; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glucose; Neocortex; Neuroglia; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyridamole; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Thioinosine; Vasodilator Agents; Xanthines | 1998 |
Neuromodulators and hypoxic hypothermia in the rat.
Topics: Adenosine; Animals; Body Temperature; Carbon Monoxide; Hypothermia; Hypoxia; Male; Naloxone; Narcotic Antagonists; Neurotransmitter Agents; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Theophylline | 1998 |
The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis.
Topics: Acidosis; Acidosis, Respiratory; Adenosine; Animals; Caffeine; Coronary Circulation; Hypercapnia; Male; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Theophylline; Triazines; Triazoles | 1998 |
Endogenous adenosine suppresses norepinephrine-induced ventricular arrhythmias in rat heart.
Topics: Adenosine; Animals; Electrocardiography; Heart; In Vitro Techniques; Male; Myocardium; Norepinephrine; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Thioinosine; Vasoconstrictor Agents; Ventricular Fibrillation | 1998 |
Metabolic regulation of endogenous adenosine release from single neurons.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dinucleoside Phosphates; Drug Administration Routes; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Models, Biological; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Theophylline; Tubercidin | 1998 |
The effect of pyrimidine nucleosides on adenosine-induced apoptosis in HL-60 cells.
Topics: Adenosine; Apoptosis; Blotting, Western; Dipyridamole; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Agar Gel; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Proto-Oncogene Proteins c-myc; Pyrimidine Nucleosides; Theophylline | 1998 |
Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
Topics: Adenosine; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; CHO Cells; Cricetinae; Entropy; Humans; Kinetics; Point Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Theophylline; Thermodynamics; Threonine; Transfection; Xanthines | 1998 |
Modulatory role of endothelium-derived relaxing factors on the flow-regulated coronary vascular resistance.
Topics: Adenosine; Animals; Coronary Vessels; Guinea Pigs; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Theophylline; Vascular Resistance | 1998 |
Optimal myocardial preconditioning in a human model of ischemia and reperfusion.
Topics: Adenosine; Dose-Response Relationship, Drug; Humans; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Protein Kinase C; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
Adenosine A2A receptors inhibit the conductance of NMDA receptor channels in rat neostriatal neurons.
Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Neostriatum; Neurons; Patch-Clamp Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Theophylline | 1998 |
Adenosine receptor antagonism affects regional resting vascular resistance during rat peritoneal sepsis.
Topics: Adenosine; Animals; Cardiac Output; Disease Models, Animal; Hemodynamics; Male; Organ Specificity; Peritonitis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sepsis; Theophylline; Vascular Resistance | 1998 |
Pharmacological interactions between magnesium ion and adenosine on monoaminergic system in the central nervous system.
Topics: Adenosine; Animals; Biogenic Monoamines; Caffeine; Carbamazepine; Central Nervous System; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Magnesium; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline; Visual Cortex | 1998 |
Modulation of cochlear blood flow by extracellular purines.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cochlea; Guinea Pigs; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Purines; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Regional Blood Flow; Theophylline; Triazines; Uridine Triphosphate | 1999 |
Involvement of P1 receptors in the effect of forskolin on cyclic AMP accumulation and export in PC12 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; PC12 Cells; Probenecid; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Time Factors | 1999 |
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents | 1999 |
Adenosine inhibits L-type Ca2+ current and catecholamine release in the rabbit carotid body chemoreceptor cells.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carotid Body; Catecholamines; Chemoreceptor Cells; Dose-Response Relationship, Drug; Electrophysiology; Hypoxia; Ion Channel Gating; Membrane Potentials; Neuroprotective Agents; omega-Conotoxin GVIA; Peptides; Potassium; Rabbits; Sodium; Tetrodotoxin; Theophylline; Tritium; Xanthines | 1999 |
Cytochrome P-450 content and activity after cold storage of rat hepatocytes in university of wisconsin and sodium-lactobionate-sucrose solutions.
Topics: Adenosine; Allopurinol; Animals; Cell Survival; Chlorpromazine; Cryopreservation; Cytochrome P-450 Enzyme System; Disaccharides; Glutathione; Insulin; Liver; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Sucrose; Theophylline | 1999 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Plasma adenosine levels and platelet activation in patients with atrial fibrillation.
Topics: Adenosine; Adult; Atrial Fibrillation; Case-Control Studies; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Receptors, Purinergic P1; Theophylline | 1999 |
Microelectrode measurements of the effects of basolateral adenosine in polarized human intestinal epithelial cells in culture.
Topics: Acetophenones; Adenosine; Bumetanide; Cell Line; Cell Membrane; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Humans; Intestines; Membrane Potentials; Microelectrodes; Phospholipases A; Phospholipases A2; Receptors, Purinergic P1; Theophylline | 1999 |
A2B adenosine receptors mediate relaxation of the pig intravesical ureter: adenosine modulation of non adrenergic non cholinergic excitatory neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Indomethacin; Male; Muscle Relaxation; Receptors, Purinergic P1; Swine; Synaptic Transmission; Theophylline; Ureter; Xanthines | 1999 |
Molecular and behavioral effects mediated by Gs-coupled adenosine A2a, but not serotonin 5-Ht4 or 5-Ht6 receptors following antipsychotic administration.
Topics: Adenosine; Animals; Antipsychotic Agents; Behavior, Animal; Caffeine; Catalepsy; Clozapine; Corpus Striatum; Cyclic AMP; Dopamine D2 Receptor Antagonists; Gene Expression Regulation; Genes, fos; GTP-Binding Protein alpha Subunits, Gs; Haloperidol; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, Purinergic P1; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Second Messenger Systems; Serotonin; Serotonin Antagonists; Theophylline | 1999 |
Factors modulating N-methyl-D-aspartate (NMDA)-induced cerebral vasodilation after hypoxia/ischemia in piglets.
Topics: Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Hypoxia, Brain; Ischemic Attack, Transient; N-Methylaspartate; Nitroprusside; Pia Mater; Swine; Theophylline; Vasodilation | 1998 |
Effect of adenosinergic modulation on the anticonvulsant effect of phenobarbitone and carbamazepine.
Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Convulsants; Drug Combinations; Male; Pentylenetetrazole; Phenobarbital; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1999 |
Adenosine modulates corticotropin and cortisol release during hypoxia in fetal sheep.
Topics: Adenosine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Bradycardia; Female; Fetal Blood; Fetal Hypoxia; Heart Rate, Fetal; Hydrocortisone; Hydrogen-Ion Concentration; Hypertension; Kinetics; Oxygen; Pregnancy; Purinergic P1 Receptor Antagonists; Sheep; Theophylline | 1999 |
Role of adenosine in local metabolic coronary vasodilation.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Electrocardiography; Heart Rate; Heart Ventricles; Hyperemia; Lactic Acid; Male; Oxygen; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasodilation; Ventricular Function | 1999 |
A novel influence of adenosine on ongoing activity in rat rostral ventrolateral medulla.
Topics: Adenosine; Animals; Antihypertensive Agents; Bicuculline; Electric Stimulation; GABA Antagonists; Hypothalamus; Male; Medulla Oblongata; Neurons; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1999 |
Effects of adenosinergic agents on the vascular resistance and on the optic nerve response in the perfused cat eye.
Topics: Adenosine; Animals; Cats; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Female; Optic Nerve; Perfusion; Phenethylamines; Photic Stimulation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retina; Theobromine; Theophylline; Vascular Resistance | 1999 |
Preanalytical requirements for flow cytometric evaluation of platelet activation: choice of anticoagulant.
Topics: Adenosine; Adult; Anticoagulants; Antigens, CD; Blood Platelets; Blood Preservation; Citrates; Dipyridamole; Female; Flow Cytometry; Humans; Male; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Sodium Citrate; Tetraspanin 30; Theophylline; Thrombin | 1999 |
Metabolic and cardiorespiratory responses to hypoxia in fetal sheep: adenosine receptor blockade.
Topics: Acids; Adenosine; Animals; Cerebral Cortex; Fetal Hypoxia; Fetus; Heart; Heart Rate; Hypertension; Injections, Intra-Arterial; Oxygen; Partial Pressure; Purinergic P1 Receptor Antagonists; Reference Values; Respiration; Sheep; Sleep, REM; Theophylline | 1999 |
Effects of A1-adenosine receptor antagonists on purinergic transmission in the guinea-pig vas deferens in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Neuroeffector Junction; Phentolamine; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Thioinosine; Vas Deferens; Xanthines; Yohimbine | 1999 |
Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices.
Topics: Adenosine; Animals; Brain Ischemia; Extracellular Space; Hippocampus; In Vitro Techniques; Kinetics; Male; Oxygen; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Xanthines | 1999 |
Amplification of the cyclic AMP response to forskolin in pheochromocytoma PC12 cells through adenosine A(2A) purinoceptors.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Inosine; Kinetics; PC12 Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sulfonamides; Theophylline | 1999 |
Optimal myocardial preconditioning in humans.
Topics: Adenosine; Adenosine Triphosphate; Cells, Cultured; Coronary Artery Bypass; Energy Metabolism; Heart Ventricles; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1999 |
Pharmacological characterization of adenosine A1 receptors and its functional role in brown trout (Salmo trutta) brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Brain; Cell Membrane; Glutamic Acid; Guanosine Diphosphate; Kinetics; Neuroprotective Agents; Radioligand Assay; Receptors, Purinergic P1; Synaptosomes; Theophylline; Tritium; Trout; Xanthines | 1999 |
Contributions of adenosine receptor activation to the ocular actions of epinephrine.
Topics: Adenosine; Adrenergic Agonists; Animals; Aqueous Humor; Epinephrine; Inosine; Intraocular Pressure; Ophthalmic Solutions; Pupil; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Role of K(+)(ATP) channels and adenosine in regulation of coronary blood flow in the hypertrophied left ventricle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Drug Combinations; Glyburide; Hypertrophy, Left Ventricular; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Theophylline | 1999 |
Possible mechanism of interaction of GABAergic-adenosinergic systems in the regulation of theophylline-induced locomotor activity under its nontolerant and tolerant conditions.
Topics: Adenosine; Animals; Cholinergic Agents; Dopamine Agents; Drug Tolerance; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Motor Activity; Rats; Serotonin Agents; Theophylline | 1999 |
The role of adenosine in insulin-induced vasodilation.
Topics: Adenosine; Adolescent; Adult; Analysis of Variance; Forearm; Humans; Insulin; Piperazines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Regional Blood Flow; Theophylline; Vascular Resistance; Vasodilation; Vasodilator Agents | 1999 |
Role of adenosine in regulation of brain temperature in fetal sheep.
Topics: Adenosine; Animals; Body Temperature Regulation; Brain; Constriction; Female; Fetal Hypoxia; Fetus; Kinetics; Pregnancy; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Umbilical Cord | 1999 |
The effects of adenosine ligands R-PIA and CPT on ethanol withdrawal.
Topics: Adenosine; Alcohol Drinking; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Ethanol; Male; Maze Learning; Purinergic P1 Receptor Agonists; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome; Theophylline | 1999 |
Interbeat interval variability in isolated working rat hearts at various dynamic conditions and temperatures.
Topics: Adenosine; Animals; Cardiac Output; Cardiotonic Agents; Chi-Square Distribution; Electrocardiography; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted; Temperature; Theophylline; Vasodilator Agents; Ventricular Function, Left | 1999 |
Role of peripheral adenosine A(1) receptors in the regulation of sleep apneas in rats.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Respiration; Sleep Apnea Syndromes; Sleep Stages; Theophylline | 1999 |
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors.
Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Caffeine; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Tritium; Xanthines | 1999 |
Elevated levels of endogenous adenosine alter metabolism and enhance reduction in contractile function during low-flow ischemia: associated changes in expression of Ca(2+)-ATPase and phospholamban.
Topics: Adenosine; Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiotonic Agents; Energy Metabolism; Female; Gene Expression Regulation; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oxygen Consumption; Piperazines; Swine; Theophylline; Ventricular Function, Left | 1999 |
Systemic adenosine increase during cold pressor test is dependent on sympathetic activation.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clonidine; Cold Temperature; Female; Heart Rate; Humans; Male; Norepinephrine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Sympathetic Nervous System; Theophylline; Vasoconstriction; Vasodilator Agents | 1999 |
The role of adenosine receptor engagement in murine fetal thymocyte development.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apoptosis; CD4 Antigens; CD8 Antigens; Cell Differentiation; Female; GTP-Binding Proteins; Mice; Mice, Inbred DBA; Organ Culture Techniques; Receptors, Purinergic P1; Signal Transduction; T-Lymphocyte Subsets; Theophylline; Thymus Gland | 1999 |
An adenosine A3 receptor-selective agonist does not modulate calcium-activated potassium currents in hippocampal CA1 pyramidal neurons.
Topics: Adenosine; Animals; Calcium; Hippocampus; In Vitro Techniques; Male; Potassium Channels; Purinergic P1 Receptor Agonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Acute peroxide treatment of rat hippocampal slices induces adenosine-mediated inhibition of excitatory transmission in area CA1.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Excitatory Postsynaptic Potentials; Ferrous Compounds; Hippocampus; Hydrogen Peroxide; Male; Neural Inhibition; Organ Culture Techniques; Oxidants; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline; Xanthines | 1999 |
Endogenous adenosine protects CA1 neurons from kainic acid-induced neuronal cell loss in the rat hippocampus.
Topics: Adenosine; Animals; Apoptosis; Disease Models, Animal; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Histocompatibility Antigens Class II; Injections, Intraventricular; Kainic Acid; Macrophage-1 Antigen; Male; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Phosphorylation; Proto-Oncogene Proteins c-jun; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1999 |
[Platelet activation in cardiology: methods, indications and therapeutic perspectives].
Topics: Adenosine; Adenosine Diphosphate; Antigens, CD; Blood Platelets; CD40 Ligand; Coronary Disease; Dipyridamole; Humans; In Vitro Techniques; Ligands; Membrane Glycoproteins; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Reference Values; Tetraspanin 30; Theophylline | 1999 |
Resistance to antagonism of atrial P(1) purinoceptor responses in the presence of K(+) channel blockade.
Topics: 4-Aminopyridine; Adenosine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Heart Atria; Male; Myocardial Contraction; Potassium Channel Blockers; Propranolol; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Reserpine; Signal Transduction; Theophylline | 1999 |
Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine; Animals; Antiparkinson Agents; Antipsychotic Agents; Caffeine; Catalepsy; Dopamine Agents; Hypokinesia; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Reserpine; Theophylline | 1999 |
Ischemic preconditioning and glucose metabolism during low-flow ischemia: role of the adenosine A1 receptor.
Topics: Adenosine; Animals; Glucose; Glycolysis; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline | 1999 |
Adenosine receptor expression and modulation of Ca(2+) channels in rat striatal cholinergic interneurons.
Topics: Adenosine; Animals; Calcium Channels, N-Type; Choline O-Acetyltransferase; Corpus Striatum; Ethylmaleimide; GTP-Binding Proteins; Guanosine Diphosphate; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Rats; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theophylline; Thionucleotides | 2000 |
Suramin-sensitive suppression of paired-pulse inhibition by adenine nucleotides in rat hippocampal slices.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Hippocampus; Male; Nerve Tissue Proteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Endothelin; Tetrazoles; Theophylline | 2000 |
Endogenous adenosine regulates the effects of low-frequency stimulation on the induction of long-term potentiation in CA1 neurons of guinea pig hippocampal slices.
Topics: Adenosine; Afferent Pathways; Animals; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Pyrazines; Receptors, Purinergic P1; Theophylline | 2000 |
The potentiation of the histamine release induced by adenosine in mast cells from guinea pig lung and heart: sharp dependence on the time of preincubation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bucladesine; Dipyridamole; Drug Interactions; Female; Guinea Pigs; Histamine Release; Lung; Male; Mast Cells; Myocardium; Theophylline; Time Factors; Vasodilator Agents | 2000 |
Effects of adenosine receptor antagonists on the responses to contrast media in the isolated rat kidney.
Topics: Adenosine; Analysis of Variance; Animals; Contrast Media; Diatrizoate; Glomerular Filtration Rate; Kidney; Male; Perfusion; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Triiodobenzoic Acids; Xanthines | 2000 |
Cellular adaptations in fat tissue of exercise-trained miniature swine: role of excess energy intake.
Topics: Adaptation, Physiological; Adenosine; Adipocytes; Adrenergic beta-Agonists; Animals; Cell Size; Dipyridamole; Energy Intake; Energy Metabolism; Epinephrine; Female; In Vitro Techniques; Lipolysis; Physical Conditioning, Animal; Receptors, Purinergic P1; Swine; Swine, Miniature; Theophylline | 2000 |
Adenosine receptors are involved in the control of acute naloxone-precipitated withdrawal: in vitro evidence.
Topics: Adenosine; Animals; Caffeine; Dipyridamole; Guinea Pigs; Ileum; In Vitro Techniques; Male; Naloxone; Narcotic Antagonists; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2000 |
Complex hippocampal responses to ATP: fade due to nucleotidase inhibition and P2-receptor-mediated adenosine release.
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Enzyme Inhibitors; Hippocampus; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Histamine H(2) receptor activated chloride conductance in myenteric neurons from guinea pig small intestine.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Calcium Channel Blockers; Chlorides; Cyclic AMP; Cyclooxygenase Inhibitors; Electric Conductivity; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guinea Pigs; Histamine; Intestine, Small; Membrane Potentials; Myenteric Plexus; Neurons; Niflumic Acid; omega-Conotoxins; Paracrine Communication; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Receptors, Histamine H2; Stress, Psychological; Theophylline; Thionucleotides | 2000 |
Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism.
Topics: Adenosine; Apoptosis; Carbazoles; Cells, Cultured; Humans; Indoles; Neutrophils; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrroles; Receptor, Adenosine A2A; Signal Transduction; Theophylline; Xanthines | 2000 |
Long-term theophylline treatment changes the effects of angiotensin II and adenosinergic agents on the seizure threshold.
Topics: Adenosine; Angiotensin II; Animals; Convulsants; Differential Threshold; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Seizures; Theophylline; Time Factors | 2000 |
Adenosine release upon spinal cord injury.
Topics: Adenosine; Animals; Glutamic Acid; Microdialysis; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Theophylline | 2000 |
Activation of adenosine A2 alpha receptors inhibits mast cell degranulation and mast cell-dependent vasoconstriction.
Topics: Adenosine; Animals; Cricetinae; Histamine Release; Inosine; Mast Cells; Mesocricetus; Microcirculation; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilator Agents | 2000 |
Cardiovascular and pulmonary response to oral administration of ATP in rabbits.
Topics: Adenosine; Adenosine Triphosphate; Administration, Oral; Animals; Cardiovascular System; Erythrocytes; Lung; Male; Purinergic Antagonists; Purines; Rabbits; Respiration; Theophylline; Time Factors; Triazines; Vascular Resistance | 2000 |
N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats.
Topics: Adenosine; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Kindling, Neurologic; Male; Rats; Rats, Wistar; Theophylline; Valproic Acid | 2000 |
Influence of adenosine agonists and antiepileptic drugs on theophylline-induced seizures in rats.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Male; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Seizures; Theophylline | 1998 |
Direct inotropic effects of propofol and adenosine on rat atrial muscle: possible mechanisms.
Topics: Adenosine; Anesthetics, Intravenous; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Glyburide; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Potassium Channel Blockers; Potassium Channels; Propofol; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Theophylline; Vasodilator Agents | 2000 |
Effects of adenosine agonists and an antagonist on excitatory transmitter release from the ischemic rabbit hippocampus.
Topics: Adenosine; Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Electroencephalography; Extracellular Space; Glutamic Acid; Hippocampus; Hypothermia, Induced; Injections, Intravenous; Microdialysis; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion; Theophylline; Xanthines | 2000 |
Adenosine primes the opening of mitochondrial ATP-sensitive potassium channels: a key step in ischemic preconditioning?
Topics: Adenosine; Animals; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Flavoproteins; Hydroxy Acids; Ischemic Preconditioning; Membrane Proteins; Oxidation-Reduction; Polymyxin B; Potassium Channels; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline; Time Factors | 2000 |
Endothelin, angiotensin II and adenosine in acute cyclosporine A nephrotoxicity.
Topics: Acute Disease; Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclosporine; Endothelins; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Perindopril; Rabbits; Renal Circulation; Theophylline; Vascular Resistance; Water | 2000 |
Adenosine receptor blockade reveals N-methyl-D-aspartate receptor- and voltage-sensitive dendritic spikes in rat hippocampal CA1 pyramidal cells in vitro.
Topics: Action Potentials; Adenosine; Animals; Dendrites; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Theophylline | 2000 |
Adenosine: A partial agonist of the growth hormone secretagogue receptor.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aequorin; Animals; Binding Sites; Cell Extracts; Cell Line; Chromatography, High Pressure Liquid; Dopamine; Humans; Hypothalamus; Indoles; Ligands; Luminescent Measurements; Mass Spectrometry; Models, Biological; Mutagenesis, Site-Directed; Neurons; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Spiro Compounds; Swine; Theophylline | 2000 |
Interdependence of adenosine and nitric oxide in hepato-splanchnic circulation during sepsis.
Topics: Adenosine; Animals; Liver Circulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Splanchnic Circulation; Theophylline | 2000 |
Role of adenosine in the spinal antinociceptive and morphine modulatory actions of neuropeptide FF analogs.
Topics: Adenosine; Analgesics, Opioid; Animals; Male; Morphine; Oligopeptides; Rats; Rats, Sprague-Dawley; Spinal Cord; Theophylline | 2000 |
The effect of adenosine on blood pressure variability in sinoaortic denervated rats is mediated by adenosine A2a-Receptor.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Blood Pressure; Denervation; Drug Interactions; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline | 2000 |
Mediation of the cardiovascular response to spinal gamma-aminobutyric acid(B) receptor stimulation by adenosine A(1) receptors in anesthetized rats.
Topics: Adenosine; Amino Acids, Neutral; Animals; Baclofen; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Spinal Cord; Sympathetic Nervous System; Theobromine; Theophylline | 2000 |
Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta.
Topics: 2-Chloroadenosine; Adenosine; Animals; Aorta; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesocricetus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Receptors, Purinergic P1; Theophylline; Thioinosine; Vasodilation | 2000 |
The liver protective effect of ischemic preconditioning may be mediated by adenosine.
Topics: Adenosine; Alanine Transaminase; Animals; Ischemia; Ischemic Preconditioning; Liver; Liver Circulation; Rats; Rats, Wistar; Reperfusion; Theophylline | 2000 |
A transient increase in temperature induces persistent potentiation of synaptic transmission in rat hippocampal slices.
Topics: Adenosine; Animals; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Temperature; Theophylline; Time Factors | 2000 |
A novel transverse push-pull microprobe: in vitro characterization and in vivo demonstration of the enzymatic production of adenosine in the spinal cord dorsal horn.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Male; Microdialysis; Nitrophenols; Physical Stimulation; Posterior Horn Cells; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Spinal Cord; Theophylline | 2001 |
K(ATP)(+) channels, nitric oxide, and adenosine are not required for local metabolic coronary vasodilation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; Male; Myocardium; Nitric Oxide; Nitroarginine; Oxygen; Oxygen Consumption; Physical Exertion; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Rest; Theophylline; Vasodilation | 2001 |
Caffeine increases paragigantocellularis neuronal firing rate and induces withdrawal signs in morphine-dependent rats.
Topics: Adenosine; Analgesics, Opioid; Animals; Caffeine; Electrophysiology; Male; Medulla Oblongata; Microinjections; Morphine; Morphine Dependence; Neurons; Purinergic P1 Receptor Agonists; Rats; Substance Withdrawal Syndrome; Theophylline | 2001 |
Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo.
Topics: Acid-Base Equilibrium; Adenosine; Animals; Blood Pressure; Caffeine; Carotid Artery, Common; Constriction; Excitatory Postsynaptic Potentials; Heart Rate; Hippocampus; Hypoxia-Ischemia, Brain; Male; Oxygen; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline | 2001 |
The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (Salmo trutta) optic tectum is inhibited by adenosine A1 receptors: effects of enucleation on A1 receptor density and cholinergic markers.
Topics: Acetylcholine; Acetylcholinesterase; Adenosine; Afferent Pathways; Animals; Calcium; Calcium Channel Blockers; Choline O-Acetyltransferase; Kinetics; Membrane Potentials; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Superior Colliculi; Synaptosomes; Theophylline; Tritium; Trout | 2001 |
Hepatic arteriolo-portal venular shunting guarantees maintenance of nutritional microvascular supply in hepatic arterial buffer response of rat livers.
Topics: Adenosine; Animals; Arteriovenous Shunt, Surgical; Erythrocytes; Hepatic Artery; Liver; Liver Circulation; Male; Microcirculation; Microscopy, Fluorescence; Oxygen Consumption; Portal Vein; Rats; Rats, Sprague-Dawley; Theophylline | 2001 |
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.
Topics: Adenosine; Animals; Caffeine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theobromine; Theophylline; Transfection | 2001 |
Antiarrhythmic effects of adenosine on ischemia-induced ventricular fibrillation.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Theophylline; Ventricular Fibrillation | 2001 |
Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.
Topics: Adenosine; Analysis of Variance; Animals; Brimonidine Tartrate; Electric Stimulation; Enzyme Inhibitors; Male; Myocardial Stunning; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Phenylisopropyladenosine; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Theophylline; Time Factors; Xanthines | 2001 |
Role of adenosine and glycogen in ischemic preconditioning of rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Glycogen; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Male; Myocardium; Phosphates; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 2001 |
Plasma adenosine levels and P-selectin expression on platelets in preeclampsia.
Topics: Adenosine; Adult; Case-Control Studies; Female; Humans; P-Selectin; Platelet Activation; Pre-Eclampsia; Pregnancy; Theophylline | 2001 |
Evidence that the renin decrease during hypoxia is adenosine mediated in conscious dogs.
Topics: Acute Disease; Adenosine; Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carbon Dioxide; Consciousness; Diet, Sodium-Restricted; Dogs; Female; Heart Rate; Hemodynamics; Hypoxia; Oxygen; Partial Pressure; Potassium; Purinergic P1 Receptor Antagonists; Renin; Renin-Angiotensin System; Theophylline | 2001 |
Effect of pre-analytical handling on haematological variables in minipigs.
Topics: Adenosine; Animals; Anticoagulants; Blood Specimen Collection; Citric Acid; Dipyridamole; Edetic Acid; Erythrocyte Count; Guidelines as Topic; Hematocrit; Hemoglobins; Leukocyte Count; Male; Platelet Count; Random Allocation; Statistics, Nonparametric; Swine; Swine, Miniature; Temperature; Theophylline; Time Factors | 2001 |
Role of adenosine in exercise-induced human skeletal muscle vasodilatation.
Topics: Adenosine; Adult; Electrophysiology; Exercise; Exercise Test; Femoral Artery; Hemodynamics; Humans; Injections, Intra-Arterial; Male; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilation; Vasodilator Agents | 2001 |
Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Antineoplastic Agents; Cilia; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Nasal Mucosa; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Theophylline; Uridine Triphosphate | 2001 |
Effect of intracarotid injection of adenosine on the activity of RVLM neurons in barodenervated rats.
Topics: Adenosine; Animals; Carotid Arteries; Carotid Sinus; Electrophysiology; Injections, Intra-Arterial; Medulla Oblongata; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1998 |
Involvement of A(3) receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: possible novel mechanism of the anti-inflammatory action of theophylline.
Topics: Adenosine; Anti-Inflammatory Agents; Cell Degranulation; Drug Interactions; Drug Synergism; Eosinophil Peroxidase; Eosinophils; Humans; In Vitro Techniques; Peroxidases; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Theophylline | 2001 |
Interaction between angiotensin IV and adenosine A(1) receptor related drugs in passive avoidance conditioning in rats.
Topics: 2-Chloroadenosine; Adenosine; Angiotensin II; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2001 |
Effect of lactate on the synaptic potential, energy metabolism, calcium homeostasis and extracellular glutamate concentration in the dentate gyrus of the hippocampus from guinea-pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycolysis; Guinea Pigs; Homeostasis; Intracellular Fluid; Lactic Acid; Neurons; Nimodipine; Organ Culture Techniques; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Theophylline | 2001 |
Hypoxic ventilatory depression in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes.
Topics: Adenosine; Adult; Humans; Hypoventilation; Hypoxia; Male; MELAS Syndrome; Theophylline; Vital Capacity | 2001 |
Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor?
Topics: Adenosine; Animals; Astrocytes; Brain; Calcium; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Extracellular Space; Guanosine; Mice; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Theophylline; Triazoles; Xanthines | 2001 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
Effect of intracarotid administration of adenosine on the activity of area postrema neurons in barodenervated rats.
Topics: Adenosine; Animals; Carotid Arteries; Carotid Sinus; Denervation; Electrophysiology; Injections, Intra-Arterial; Male; Medulla Oblongata; Neurons; Pressoreceptors; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1999 |
Role of adenosine in ischemic preconditioning in rats depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors.
Topics: Acetamides; Adenosine; Analysis of Variance; Animals; Cryoprotective Agents; Dihydropyridines; Histamine H1 Antagonists; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Pyrilamine; Rats; Rats, Wistar; Receptors, Purinergic; Receptors, Purinergic P1; Theophylline; Time Factors | 2001 |
Role of adenosine in asthma.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Bronchodilator Agents; Dogs; Humans; Lung; Mast Cells; Mice; Rats; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Theophylline; Xanthines | 1996 |
Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tubercidin | 2001 |
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines | 2001 |
Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves.
Topics: Adenosine; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Digestive System; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfones; Theophylline; Time Factors | 2001 |
Activation of adenosine A1 receptors by drugs to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Adenosine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Streptozocin; Theophylline; Triglycerides; Xanthines | 2000 |
Platelet aggregability in syndrome X: a role for adenosine.
Topics: Adenosine; Exercise Test; Humans; Microvascular Angina; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2001 |
Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Astrocytoma; Brain Neoplasms; Cell Death; Cell Division; Humans; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Theophylline; Tumor Cells, Cultured; Uridine Triphosphate | 2001 |
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2001 |
Role of adenosine and P2 receptors in the penile tumescence in anesthetized dogs.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Penile Erection; Penis; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Triazoles | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
Topics: Adenosine; Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Ischemia; Ischemic Preconditioning; Kidney; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery Obstruction; Renal Circulation; Reperfusion Injury; Theobromine; Theophylline; Time Factors; Ultrasonography, Doppler, Pulsed; Xanthines | 2001 |
Catalepsy induced by a blockade of dopamine D1 or D2 receptors was reversed by a concomitant blockade of adenosine A(2A) receptors in the caudate-putamen of rats.
Topics: Adenosine; Animals; Benzazepines; Catalepsy; Caudate Nucleus; Dopamine Antagonists; Drug Interactions; Male; Phosphodiesterase Inhibitors; Prodrugs; Purinergic P1 Receptor Antagonists; Putamen; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; Sulpiride; Theophylline; Xanthines | 2001 |
Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amnesia; Analysis of Variance; Animals; Avoidance Learning; Convulsants; Dose-Response Relationship, Drug; Male; Mice; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retention, Psychology; Theophylline | 2001 |
Decreases in portal flow trigger a hepatorenal reflex to inhibit renal sodium and water excretion in rats: role of adenosine.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Denervation; Diuresis; Hepatorenal Syndrome; Kidney; Ligation; Liver; Male; Mesenteric Artery, Superior; Natriuresis; Portacaval Shunt, Surgical; Portal System; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reflex; Renal Artery; Theophylline | 2002 |
Hippocampal injury and neurobehavioral deficits following hyperglycemic cerebral ischemia: effect of theophylline and ZM 241385.
Topics: Adenosine; Animals; Blood Glucose; Cell Death; Cerebral Infarction; Escape Reaction; Hippocampus; Injections, Intraperitoneal; Male; Maze Learning; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles | 2002 |
Regulation of renal A(1) adenosine receptors in vivo.
Topics: Adenosine; Animals; Cell Membrane; GTP-Binding Proteins; Immunoblotting; Kidney; Kidney Cortex; Kinetics; Male; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renin; Theophylline; Time Factors; Xanthines | 2002 |
Interaction of angiotensin II and III with adenosine A(1) receptor-related drugs in passive avoidance conditioning in rats.
Topics: Adenosine; Angiotensin II; Angiotensin III; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Memory; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2002 |
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Nucleotides; Potassium; Rats; Rats, Wistar; Theophylline; Thionucleotides; Vas Deferens | 2002 |
Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.
Topics: Adenosine; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium; Cells, Cultured; Dermis; DNA Primers; Endothelial Growth Factors; Gene Expression; Hair; Humans; Hypertrichosis; Lymphokines; Minoxidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Antagonists; Receptors, Drug; Receptors, Purinergic P1; Sulfonylurea Receptors; Theobromine; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2001 |
Enhancement of cellular adenosine triphosphate levels in PC12 cells by extracellular adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coformycin; Dipyridamole; PC12 Cells; Rats; Receptors, Purinergic P1; Theophylline; Tubercidin | 2002 |
Dopaminergic mechanism for caffeine-produced cocaine seeking in rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzazepines; Caffeine; Central Nervous System Stimulants; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Self Administration; Theophylline; Vasodilator Agents | 2002 |
[The role of theophylline in the improvement of scop-induced learning and memory impairment].
Topics: Acetylcholine; Adenosine; Animals; Brain; Chromatography, High Pressure Liquid; Learning; Male; Memory Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Scopolamine; Theophylline | 2000 |
Systemic theophylline augments the blood oxygen level-dependent response to forepaw stimulation in rats.
Topics: Adenosine; Animals; Brain Mapping; Cerebrovascular Circulation; Electric Stimulation; Forelimb; Magnetic Resonance Imaging; Male; Oxygen; Rats; Rats, Sprague-Dawley; Theophylline; Vasodilation | 2002 |
Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats.
Topics: Adenosine; Animals; Blood Pressure; Glyburide; Heart Rate; Kidney; Medulla Oblongata; Microinjections; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Theophylline; Xanthines | 2000 |
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure | 2002 |
Adenosine inhibition via A(1) receptor of N-type Ca(2+) current and peptide release from isolated neurohypophysial terminals of the rat.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine Vasopressin; Barium; Calcium Channels, N-Type; In Vitro Techniques; Kinetics; Membrane Potentials; Nerve Endings; Oxytocin; Patch-Clamp Techniques; Pituitary Gland, Posterior; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline | 2002 |
Evaluation of the anticoagulants EDTA and citrate, theophylline, adenosine, and dipyridamole (CTAD) for assessing platelet activation on the ADVIA 120 hematology system.
Topics: Adenosine; Adult; Anticoagulants; Blood Platelets; Blood Specimen Collection; Cell Aggregation; Cell Size; Citrates; Dipyridamole; Edetic Acid; Flow Cytometry; Hematologic Tests; Humans; In Vitro Techniques; Leukocytes; P-Selectin; Platelet Activation; Platelet Count; Temperature; Theophylline | 2002 |
Magnesium reduces myocardial infarct size via enhancement of adenosine mechanism in rabbits.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Analysis of Variance; Animals; Calcium; Drug Synergism; Enzyme Inhibitors; Magnesium; Male; Models, Animal; Myocardial Infarction; Myocardium; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 2002 |
Protective effect of resveratrol against pentylenetetrazole-induced seizures and its modulation by an adenosinergic system.
Topics: Adenosine; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Resveratrol; Seizures; Stilbenes; Theophylline | 2002 |
Sites of action of adenosine in interorgan preconditioning of the heart.
Topics: Adenosine; Animals; Blood Pressure; Coronary Vessels; Ganglionic Blockers; Heart Rate; Hexamethonium; Injections, Intra-Arterial; Injections, Intravenous; Intestine, Small; Ischemia; Ischemic Preconditioning, Myocardial; Male; Mesenteric Arteries; Mesentery; Myocardial Infarction; Myocardial Ischemia; Myocardium; Portal Vein; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2002 |
Complementary effects of adenosine and angiotensin II in hypoxemia-induced renal dysfunction in the rabbit.
Topics: Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Gas Analysis; Hypoxia; Indoles; Inulin; Kidney Diseases; Kidney Function Tests; Male; Rabbits; Renal Circulation; Theophylline; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Adenosine-mediated bronchoconstriction and lung inflammation in an allergic mouse model.
Topics: Adenosine; Allergens; Animals; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Theophylline; Vasodilator Agents | 2002 |
Inhibition of vaccinia virus replication by adenosine in BSC-40 cells: involvement of A(2) receptor-mediated PKA activation.
Topics: Adenosine; Animals; Antiviral Agents; Carrier Proteins; Cell Line; Coculture Techniques; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Intracellular Signaling Peptides and Proteins; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Theobromine; Theophylline; Vaccinia virus; Virus Replication | 2002 |
Effect of hypoxia on excitatory transmission in the rat substantia gelatinosa neurons.
Topics: Adenosine; Analgesics; Animals; Electrophysiology; Hypoxia; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Synapses; Theophylline; Time Factors | 2002 |
[The effect of dipyridamole and adenosine on pulmonary fibrosis in mice].
Topics: Adenosine; Animals; Bleomycin; Cell Count; Dipyridamole; Lung; Macrophages, Alveolar; Mice; Microscopy, Electron; Pulmonary Alveoli; Pulmonary Circulation; Pulmonary Fibrosis; Theophylline; Time Factors; Vasodilator Agents | 2002 |
Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo.
Topics: Adenosine; Animals; Cell Death; Cerebrovascular Circulation; Hippocampus; Hypoxia-Ischemia, Brain; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Organ Culture Techniques; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Subcellular Fractions; Synaptic Transmission; Theophylline; Up-Regulation | 2002 |
Optimized flow cytometric assay for the measurement of platelet microparticles in plasma: pre-analytic and analytic considerations.
Topics: Adenosine; Adult; Anticoagulants; beta-Thromboglobulin; Biomarkers; Blood Platelets; Blood Preservation; Blood Specimen Collection; Citrates; Dipyridamole; Flow Cytometry; Humans; Microspheres; Particle Size; Platelet Activation; Reproducibility of Results; Sensitivity and Specificity; Sodium Citrate; Solutions; Theophylline | 2002 |
A1 adenosine receptor activation induces ventriculomegaly and white matter loss.
Topics: Adenosine; Animals; Animals, Newborn; Body Weight; Cell Count; Cerebral Cortex; Cerebral Ventricles; Drug Combinations; Drug Interactions; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Microscopy, Electron; Myelin Basic Protein; Nerve Degeneration; Nerve Fibers, Myelinated; Neuroglia; Neurons; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Telencephalon; Theophylline | 2002 |
Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators.
Topics: Adenosine; Animals; Dipyridamole; Glucose; Islets of Langerhans; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Theobromine; Theophylline; Vagotomy; Vasodilator Agents; Xanthines | 2002 |
Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells.
Topics: Adenosine; Animals; Cattle; Cell Line, Transformed; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Time Factors; Trabecular Meshwork | 2002 |
Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus.
Topics: Adenosine; Animals; Cardiovascular Physiological Phenomena; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline | 2002 |
The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Gestational Age; Heart Rate; Hemoglobins; Hydrogen-Ion Concentration; Hypoxia, Brain; Injections, Intravenous; Lactic Acid; Laser-Doppler Flowmetry; Oxygen; Pregnancy; Purinergic P1 Receptor Antagonists; Theophylline; Vascular Resistance; Vasodilator Agents | 2002 |
Interactions of adenosine, prostaglandins and nitric oxide in hypoxia-induced vasodilatation: in vivo and in vitro studies.
Topics: Adenosine; Animals; Aorta; Cyclooxygenase Inhibitors; Diclofenac; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle, Skeletal; Nitric Oxide; Prostaglandins; Rats; Rats, Wistar; Theophylline; Vasodilation | 2002 |
The adenosine antagonist theophylline impairs p50 auditory sensory gating in normal subjects.
Topics: Acoustic Stimulation; Adenosine; Adult; Auditory Pathways; Auditory Perception; Brain; Evoked Potentials, Auditory; Female; Humans; Male; Middle Aged; Neural Inhibition; Phosphodiesterase Inhibitors; Reaction Time; Schizophrenia; Sex Factors; Theophylline | 2002 |
Possible role of mast cells in cineole-induced scratching behavior in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Cyclohexanols; Cyproheptadine; Diphenhydramine; Eucalyptol; Histamine H1 Antagonists; Male; Mast Cells; Mice; Monoterpenes; Naloxone; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Serotonin Antagonists; Terpenes; Theophylline | 2002 |
Adenosine uptake inhibition ameliorates cerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Adenosine; Amylases; Animals; Biological Transport; Ceruletide; Dipyridamole; Female; Lipase; Mice; Mice, Inbred BALB C; Models, Chemical; Pancreatitis; Piperazines; Pyrimidinones; Quinazolines; Theophylline | 2002 |
Role of changes in tissular nucleotides on the development of apoptosis during ischemia/reperfusion in rat small bowel.
Topics: Adenosine; Animals; Apoptosis; Caspase 3; Caspases; Cold Temperature; Intestinal Mucosa; Intestine, Small; Male; Nitric Oxide; Nitrogen Oxides; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reperfusion Injury; Spermine; Theophylline; Xanthine | 2002 |
Spinal adenosine receptor activation inhibits inflammation and joint destruction in rat adjuvant-induced arthritis.
Topics: Adenosine; Animals; Arthritis, Experimental; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Lew; Receptors, Purinergic P1; Spinal Cord; Theophylline; Transcription Factor AP-1 | 2002 |
The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics, Opioid; Animals; Learning; Male; Memory; Mice; Morphine; Receptors, Purinergic P1; Theophylline; Vasodilator Agents | 2002 |
Saturation of neuroprotective effects of adenosine in cortical culture.
Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular Space; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2002 |
Resetting intrinsic purinergic modulation of neural activity: an associative mechanism?
Topics: 5'-Nucleotidase; Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Association; Behavior, Animal; Calcium; Electric Stimulation; Embryo, Nonmammalian; Enzyme Activation; Feedback, Physiological; Kinetics; Models, Neurological; Motor Activity; Nerve Net; Neurons; Potassium; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Swimming; Synaptic Transmission; Theophylline; Xenopus | 2002 |
Purinergic modulation of neuronal activity in the mesolimbic dopaminergic system in vivo.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dopamine; Electroencephalography; Male; Microdialysis; Neurons; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Purines; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Ventral Tegmental Area | 2003 |
Regulation by Rab3A of an endogenous modulator of neurotransmitter release at mouse motor nerve endings.
Topics: Acetylcholine; Adenosine; Animals; Diaphragm; Electric Stimulation; Electrophysiology; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Patch-Clamp Techniques; Phenotype; Phrenic Nerve; Purinergic P1 Receptor Antagonists; rab3A GTP-Binding Protein; Theophylline | 2002 |
Ethylenediaminetetraacetic acid plus citrate-theophylline-adenosine-dipyridamole (EDTA-CTAD): a novel anticoagulant for the flow cytometric assessment of platelet and neutrophil activation ex vivo in whole blood.
Topics: Adenosine; Adult; Anticoagulants; Blood Platelets; CD11b Antigen; Citrates; Dipyridamole; Edetic Acid; Female; Flow Cytometry; Humans; L-Selectin; Leukocyte Common Antigens; Male; Membrane Glycoproteins; Middle Aged; Neutrophil Activation; Neutrophils; P-Selectin; Particle Size; Platelet Activation; Theophylline | 2003 |
Intrarenal kinetics: effect of adenosine and theophylline.
Topics: Adenosine; Contrast Media; Humans; Kidney Diseases; Kidney Failure, Chronic; Theophylline; Vasodilator Agents | 2003 |
Characterisation of an uridine-specific binding site in rat cerebrocortical homogenates.
Topics: Adenosine; Animals; Binding Sites; Binding, Competitive; Bromouracil; Cell Fractionation; Cerebral Cortex; Dizocilpine Maleate; Kainic Acid; Kinetics; Male; Rats; Rats, Wistar; Suramin; Synaptic Membranes; Theophylline; Uridine | 2003 |
Coronary blood flow regulation in exercising swine involves parallel rather than redundant vasodilator pathways.
Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Circulation; Enzyme Inhibitors; Female; Glyburide; Hemodynamics; Hypoglycemic Agents; In Vitro Techniques; KATP Channels; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxygen Consumption; Physical Exertion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rest; Swine; Theophylline; Vasodilation | 2003 |
Resveratrol provides late-phase cardioprotection by means of a nitric oxide- and adenosine-mediated mechanism.
Topics: Adenosine; Animals; Cardiotonic Agents; Coronary Circulation; Enzyme Inhibitors; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Theophylline; Time Factors; Vasodilator Agents | 2003 |
Adenosine receptors do not mediate the melatonin protection against pentylenetetrazole induced seizures in rats.
Topics: Adenosine; Animals; Anticonvulsants; Male; Melatonin; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Seizures; Theophylline | 2001 |
The influence of adenosine A3 receptor agonist: IB-MECA, on scopolamine- and MK-801-induced memory impairment.
Topics: Adenosine; Animals; Avoidance Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Maze Learning; Memory; Memory Disorders; Mice; Motor Activity; Muscarinic Antagonists; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Scopolamine; Theophylline | 2003 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Systemic hypoxia and the depression of synaptic transmission in rat hippocampus after carotid artery occlusion.
Topics: Adenosine; Animals; Carotid Arteries; Cerebrovascular Circulation; Electrophysiology; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; Hypoxia; In Vitro Techniques; Injections, Intraventricular; Laser-Doppler Flowmetry; Male; Oxygen; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Theophylline | 2003 |
Benefit of theophylline administration in tacrolimus-induced nephrotoxicity in rats.
Topics: Adenosine; Animals; Creatinine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Tacrolimus; Theophylline; Vasoconstriction; Vasodilator Agents | 2003 |
The effect of acute hypoxemia and hypotension on adenosine-mediated depression of evoked hippocampal synaptic transmission.
Topics: Acute Disease; Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Carotid Artery, Common; Cerebrovascular Circulation; Excitatory Postsynaptic Potentials; Hippocampus; Hypotension; Hypoxia; Male; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Production of piglets derived from in vitro-produced blastocysts fertilized and cultured in chemically defined media: effects of theophylline, adenosine, and cysteine during in vitro fertilization.
Topics: Adenosine; Animals; Blastocyst; Cells, Cultured; Culture Media; Cysteine; Dose-Response Relationship, Drug; Embryo Transfer; Female; Fertilization in Vitro; Male; Semen; Swine; Theophylline; Time Factors | 2003 |
Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
Topics: Adenosine; Animals; Auditory Pathways; Baclofen; Blotting, Western; Brain Stem; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Neural Inhibition; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Synaptophysin; Tetrodotoxin; Theophylline | 2003 |
[Treatment of myocardial infarct].
Topics: Adenosine; Humans; Myocardial Infarction; Nikethamide; Theophylline | 1954 |
[Effect of lacarnol, oxyethyltheophyllin, dioxypropyltheophyllin and of combinations of these substances on coronary circulation and cardiac metabolism].
Topics: Adenosine; Coronary Circulation; Heart; Humans; Theophylline; Tissue Extracts | 1957 |
[Clinical experiences with the new vasodilator permanil].
Topics: Adenosine; Cardiovascular Diseases; Theophylline; Tissue Extracts; Vasodilator Agents | 1957 |
[Clinical research on cardiac and dynamic circulatory effect of a theophylline-adenosine combination (parmanil)].
Topics: Adenosine; Biomedical Research; Cardiovascular System; Heart; Theophylline; Vasoconstrictor Agents; Vasodilator Agents | 1957 |
[Some effects of adenosine in combination with beta-hydroxypropyltheophylline].
Topics: Adenosine; Theophylline | 1957 |
[Theophylline-nucleoside therapy in coronary and cerebral circulatory disorders with parmanil].
Topics: Adenosine; Brain; Cerebrovascular Circulation; Coronary Disease; Theophylline; Vasoconstrictor Agents; Vasodilator Agents | 1957 |
[Coronary insufficiency treated with adenosinetheophylline].
Topics: Adenosine; Anti-Arrhythmia Agents; Coronary Artery Disease; Coronary Disease; Diuretics; Humans; Theophylline | 1959 |
[Rational heart therapy with digoxin-purine body combinations].
Topics: Adenosine; Digoxin; Diuretics; Heart Diseases; Humans; Purines; Theobromine; Theophylline | 1959 |
[Adenosine in cardiovascular disorders].
Topics: Adenosine; Cardiovascular Diseases; Theophylline | 1959 |
ACTIVATION OF AN EPINEPHRINE-SENSITIVE LIPOLYTIC ACTIVITY FROM ADIPOSE TISSUE BY ADENOSINE 3',5'-PHOSPHATE.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adipose Tissue; Caffeine; Calcium; Epididymis; Epinephrine; Humans; Lipid Metabolism; Lipolysis; Male; Pharmacology; Phosphates; Rats; Research; Theophylline | 1964 |
THE ASSAY OF ADENOSINE-3' ,5'-PHOSPHATE IN SKELETAL MUSCLE.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Histocytochemistry; Hot Temperature; Magnesium; Muscle, Skeletal; Muscles; Phosphates; Phosphorylase Kinase; Research; Theophylline; Tissue Extracts; Trypsin; Xanthines | 1964 |
EFFECT OF PROSTAGLANDIN (PGE-1) ON THE PERMEABILITY RESPONSE OF TOAD BLADDER TO VASOPRESSIN, THEOPHYLLINE AND ADENOSINE 3',5'-MONOPHOSPHATE.
Topics: Adenine Nucleotides; Adenosine; Animals; Anura; Biological Products; Bufonidae; Permeability; Pharmacology; Prostaglandins; Prostaglandins E; Research; Theophylline; Urinary Bladder; Vasopressins | 1965 |
[PARENTERAL EFFICACY OF HIGH-DOSED ADENOSINE-THEOPHYLLINE ADMINISTRATION COMBINED WITH NICOTINATE].
Topics: Adenosine; Niacin; Nicotinic Acids; Nucleosides; Theophylline; Thromboembolism | 1965 |
[Clinical experimental studies on the metabolic effects of digitoxin, hydroxyethyltheophylline-adenosine and the combination of these substances].
Topics: Adenosine; Digitalis; Digitalis Glycosides; Digitoxin; Fructose-Bisphosphate Aldolase; Humans; Lactates; Nucleosides; Nucleotides; Theophylline | 1962 |
The similarity of effects of vasopressin, adenosine-3',5'-phosphate (cyclic AMP) and theophylline on the toad bladder.
Topics: Adenine Nucleotides; Adenosine; Cyclic AMP; Phosphates; Theophylline; Urinary Bladder; Vasopressins | 1962 |
Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Fetal Hypoxia; Gestational Age; Hemoglobins; Infusions, Intravenous; Lactic Acid; Oxyhemoglobins; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Xanthines | 2003 |
Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning.
Topics: Adenosine; Animals; Bradycardia; Chemical Warfare Agents; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Heart Diseases; Hypotension; Injections, Intramuscular; Male; Poisoning; Purinergic P1 Receptor Agonists; Rats; Sarin; Theophylline | 2004 |
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Guinea Pigs; Histamine; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Signal Transduction; Tetrodotoxin; Theophylline | 2003 |
Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Methamphetamine; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Xanthines | 2003 |
Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine.
Topics: Adenosine; Adenosine Monophosphate; Amino Acid Sequence; Animals; Calcium; Cell Line; Cell Line, Tumor; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Kinetics; Ligands; Mice; Molecular Sequence Data; Phosphorylation; Phylogeny; Protein Binding; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Purinergic P1; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sequence Homology, Amino Acid; Signal Transduction; Theophylline; Time Factors; Tissue Distribution | 2004 |
Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts.
Topics: 2-Aminoadipic Acid; Adenosine; Animals; Cardiotonic Agents; Dogs; Methotrexate; Myocardial Infarction; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2004 |
Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner.
Topics: Adenosine; Animals; Animals, Newborn; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indoles; Maleimides; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Seizures; Theophylline; Time Factors; Triazines; Triazoles | 2004 |
The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System; Synaptic Transmission; Theobromine; Theophylline; Triazines; Triazoles | 2004 |
Effects of extracellular nucleotides and their hydrolysis products on regulatory volume decrease of trout hepatocytes.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Algorithms; Animals; Cell Size; Extracellular Space; Goldfish; Hepatocytes; Hydrolysis; In Vitro Techniques; Kinetics; Nucleotides; Oncorhynchus mykiss; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline | 2004 |
Glutamate-evoked release of adenosine and regulation of peripheral nociception.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrates; Conditioning, Psychological; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Gliosis; Glutamic Acid; Male; Microglia; Neural Inhibition; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Theophylline | 2004 |
Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion.
Topics: Adenosine; Animals; Drug Administration Routes; Extracellular Fluid; Infusions, Parenteral; Kynurenic Acid; Male; Microdialysis; Neostriatum; Neurons; Phenethylamines; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Theophylline; Wakefulness | 2004 |
Theophylline, a methylxanthine derivative, suppresses absence epileptic seizures in WAG/Rij rats.
Topics: Adenosine; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Epilepsy, Absence; Rats; Rats, Wistar; Theophylline | 2004 |
Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials, Motor; Female; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Reflex, Monosynaptic; Spinal Cord; Spinal Nerve Roots; Stress, Mechanical; Theophylline | 2004 |
Adenosine A(1)-receptor-mediated tonic inhibition of glutamate release at rat hippocampal CA3-CA1 synapses is primarily due to inhibition of N-type Ca(2+) channels.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; Rats; Rats, Wistar; Receptor, Adenosine A1; Synapses; Synaptic Transmission; Theophylline | 2004 |
Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synaptic Transmission; Theophylline | 2004 |
Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.
Topics: 4-Aminopyridine; Adenosine; alpha-Synuclein; Analgesics; Anesthetics, Local; Animals; Blotting, Western; Drug Interactions; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Potassium Channel Blockers; Synaptic Transmission; Synucleins; Tetrodotoxin; Theophylline; Time Factors | 2004 |
Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 2005 |
Effect of caffeine on cerebral blood flow response to somatosensory stimulation.
Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Cerebrovascular Circulation; Electric Stimulation; Injections, Intravenous; Male; Physical Stimulation; Pia Mater; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Somatosensory Cortex; Theophylline; Vasodilation; Vasodilator Agents | 2005 |
Adenosine and ATP-sensitive potassium channels modulate dopamine release in the anoxic turtle (Trachemys scripta) striatum.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Diacetyl; Dopamine; Dopamine Uptake Inhibitors; Hypoxia; Piperazines; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Time Factors; Turtles | 2005 |
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Potassium Chloride; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana ridibunda; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Temperature; Theophylline | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Enzyme Inhibitors; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Protein Kinase C; Quinazolines; Rabbits; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-1; Staurosporine; Theophylline; Tyramine; Vasodilator Agents | 2005 |
Apoptosis inhibition during preservation by fructose-1,6-diphosphate and theophylline in rat intestinal transplantation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Bacterial Translocation; Disease Models, Animal; Fructosediphosphates; Ischemia; Jejunum; Male; Neutrophil Infiltration; Organ Preservation Solutions; Prospective Studies; Rats; Rats, Wistar; Reference Values; Theophylline | 2005 |
Blockade of intrahepatic adenosine receptors improves urine excretion in cirrhotic rats induced by thioacetamide.
Topics: Adenosine; Animals; Female; Injections, Intravenous; Kidney; Liver; Liver Circulation; Liver Cirrhosis; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Sodium; Theophylline; Thioacetamide; Urine | 2005 |
Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy.
Topics: Adenosine; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Neural Conduction; Phenethylamines; Purinergic P2 Receptor Agonists; Rats; Regional Blood Flow; Sciatic Nerve; Staining and Labeling; Streptozocin; Theophylline; Time Factors; Triazines; Triazoles | 2005 |
Adenosinergic modulation of ventilation in obese zucker rats.
Topics: Adenosine; Aminophylline; Animals; Carbon Dioxide; Hypercapnia; Hypoxia; Male; Obesity; Oxygen; Oxygen Consumption; Rats; Rats, Zucker; Respiration; Theophylline | 2005 |
Phase-specific central regulatory systems of hibernation in Syrian hamsters.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Antibodies; Arousal; Basal Metabolism; Body Temperature; Body Temperature Regulation; Brain; Circadian Rhythm; Cricetinae; Female; Hibernation; Injections, Intraventricular; Male; Mesocricetus; Narcotic Antagonists; Opioid Peptides; Receptor, Adenosine A1; Receptors, Opioid, mu; Respiratory Physiological Phenomena; Theophylline; Thyrotropin-Releasing Hormone; Time Factors | 2005 |
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Xanthines | 2005 |
Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.
Topics: Adenosine; Adenosine Deaminase; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Emodin; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Valine | 2005 |
Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine.
Topics: 3-O-Methylglucose; Adenosine; Adenosine Monophosphate; Animals; Colforsin; Female; Glucose; Intestinal Absorption; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Signal Transduction; Sodium-Glucose Transporter 1; Stimulation, Chemical; Theobromine; Theophylline | 2005 |
A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts.
Topics: Adenosine; Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Dogs; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Superoxide Dismutase; Theophylline; Vasodilator Agents | 2005 |
Platelet release of beta-thromboglobulin and platelet factor 4 and serotonin in plasma samples.
Topics: Adenosine; Adult; beta-Thromboglobulin; Blood Platelets; Chemokines, CXC; Citric Acid; Dipyridamole; Edetic Acid; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Factor 4; Serotonin; Theophylline | 2005 |
Factors influencing adenovirus-mediated airway transduction in fetal mice.
Topics: Adenosine; Adenoviridae; Animals; Carbon; Carbon Dioxide; Colloids; Cystic Fibrosis; Enzyme-Linked Immunosorbent Assay; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Lung; Mice; Theophylline; Time Factors; Trachea; Transgenes | 2005 |
In vitro fertilization and subsequent development of porcine oocytes using cryopreserved and liquid-stored spermatozoa from various boars.
Topics: Adenosine; Animals; Blastocyst; Culture Media; Cysteine; Female; Fertilization in Vitro; Male; Oocytes; Pregnancy; Semen Preservation; Sperm Capacitation; Sperm Motility; Spermatozoa; Swine; Theophylline | 2005 |
Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anterior Eye Segment; Aqueous Humor; Cattle; Dipeptides; Dose-Response Relationship, Drug; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Protease Inhibitors; Receptor, Adenosine A1; Theophylline; Time Factors | 2005 |
A structural study of new potent and selective antagonists to the A2B adenosine receptor.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Asparagine; Caffeine; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Histidine; Humans; Hydrogen Bonding; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Theophylline; Xanthines | 2005 |
Effects of single and long-term theophylline treatment on the threshold of mechanical nociception: contribution of adenosine A1 and alpha2-adrenoceptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analgesics; Animals; Male; Pain Measurement; Pain Threshold; Prazosin; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline | 2005 |
Modulation of visual inputs to accessory optic system by theophylline during hypoxia.
Topics: Action Potentials; Adenosine; Animals; Brain Stem; Excitatory Postsynaptic Potentials; Hypoxia; Neurons; Oxygen Consumption; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Reflex; Retina; Theophylline; Turtles; Visual Pathways; Visual Perception | 2006 |
Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Endocytosis; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline; Xanthines | 2006 |
A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death.
Topics: Adenosine; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Astrocytoma; Caspases; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Immunohistochemistry; Mitochondrial Membranes; Models, Biological; Multienzyme Complexes; Protein Serine-Threonine Kinases; Rats; Receptor, Adenosine A1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Theophylline; Thiazoles | 2006 |
Activity-dependent feedback modulation of spike patterning of supraoptic nucleus neurons by endogenous adenosine.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Feedback, Physiological; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Supraoptic Nucleus; Theophylline | 2006 |
Molecular mechanisms of adenosine-induced apoptosis in human HepG2 cells.
Topics: Adenosine; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dipyridamole; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Liver Neoplasms; Membrane Potentials; Mitochondria, Liver; Theophylline | 2006 |
Acute dilatory and negative inotropic effects of homocysteine are inhibited by an adenosine blocker.
Topics: Acetylcholine; Adenosine; Animals; Anti-Arrhythmia Agents; Atropine; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relationship, Drug; Heart Rate; Homocysteine; In Vitro Techniques; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Rats; Rats, Sprague-Dawley; Theophylline; Vasodilation; Vasodilator Agents | 2006 |
Post- and prejunctional consequences of ecto-ATPase inhibition: electrical and contractile studies in guinea-pig vas deferens.
Topics: Action Potentials; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Electrophysiology; Guinea Pigs; Male; Muscle Contraction; Neuromuscular Junction; Receptor, Adenosine A1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Signal Transduction; Synaptic Transmission; Theophylline; Time Factors; Vas Deferens | 2006 |
The role of adenosine in the early respiratory and cardiovascular changes evoked by chronic hypoxia in the rat.
Topics: Adenosine; Animals; Blood Pressure; Cardiovascular System; Enzyme Inhibitors; Guanidines; Heart Rate; Hemodynamics; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptor, Adenosine A1; Respiration; Respiratory Function Tests; Theophylline; Xanthines | 2006 |
Changes in atrium and thoracic aorta reactivity to adenosinergic and adrenergic agonists in experimental hyperhomocysteinemia.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Blood Pressure; Dipyridamole; Heart Atria; Heart Rate; Homocysteine; Hyperhomocysteinemia; Isoproterenol; Male; Methionine; Phenylephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Vasoconstriction; Vasodilation | 2006 |
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Angiotensin II; Animals; Arterioles; Feedback; Female; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Purines; Receptor, Adenosine A1; Receptors, Adenosine A2; Theophylline; Triazines; Triazoles; Vasoconstriction; Vasodilation | 2006 |
Accumulation of extracellular ATP protects against acute reperfusion injury in rat heart endothelial cells.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apyrase; Cells, Cultured; Coronary Vessels; Endothelial Cells; Extracellular Fluid; Male; Myocardial Reperfusion Injury; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline | 2006 |
Regional vascular responses to ATP and ATP analogues in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cyclooxygenase Inhibitors; Ibuprofen; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Receptors, Purinergic P2; Regional Blood Flow; Renal Circulation; Theophylline | 2006 |
Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Drug Administration Schedule; Functional Laterality; Guanosine 5'-O-(3-Thiotriphosphate); Physical Stimulation; Protein Binding; Rats; Receptor, Adenosine A1; Sensory Thresholds; Spinal Cord; Spinal Cord Diseases; Sulfur Isotopes; Theophylline | 2006 |
The impact of hypoxia on in vivo glucose uptake in a hypoglycemic fish, Myoxocephalus scorpius.
Topics: Adenosine; Animals; Atropine; Blood Glucose; Brain Chemistry; Carbohydrate Metabolism; Cardiac Output; Deoxyglucose; Extracellular Fluid; Fishes; Glucose; Glucose-6-Phosphate; Heart Rate; Hypoxia; Lactic Acid; Muscarinic Antagonists; Phosphorylation; Purinergic P1 Receptor Antagonists; Theophylline; Tissue Distribution | 2007 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Receptor, Adenosine A1; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2007 |
Anticonvulsant effects of focal and intracerebroventricular adenosine on penicillin-induced epileptiform activity in rats.
Topics: Action Potentials; Adenosine; Animals; Anticonvulsants; Brain; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Penicillins; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2007 |
Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Ischemic Preconditioning; Lung; Male; Malondialdehyde; Muscle Contraction; Muscle, Smooth, Vascular; Organ Size; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Theophylline; Xanthines | 2007 |
Theophylline attenuates microwave-induced impairment of memory acquisition.
Topics: Adenosine; Animals; Avoidance Learning; Body Temperature; Fever; Hippocampus; Male; Memory; Memory Disorders; Mice; Microwaves; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Radiation Dosage; Receptors, Purinergic P1; Theophylline; Treatment Outcome | 2007 |
Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline | 2007 |
Changes in neuromodulatory effect of adenosine A1 receptors on piriform cortex field potentials in amygdala kindled rats.
Topics: Adenosine; Amygdala; Animals; Excitatory Postsynaptic Potentials; Kindling, Neurologic; Male; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Theophylline | 2007 |
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide Synthase; Nitrites; Perfusion; Rats; Regional Blood Flow; Theophylline; Time Factors; Troponin I; Ventricular Function, Left | 2007 |
Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids.
Topics: Adenosine; Adult; Anticoagulants; beta-Thromboglobulin; Blood Chemical Analysis; Citric Acid; Dipyridamole; Edetic Acid; Humans; In Vitro Techniques; Lysophosphatidylcholines; Lysophospholipids; Multienzyme Complexes; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphodiesterase I; Phosphoric Diester Hydrolases; Platelet Activation; Pyrophosphatases; Theophylline | 2007 |
Involvement of adenosinergic receptors in anxiety related behaviours.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Caffeine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Female; Male; Maze Learning; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2007 |
The central role of adenosine in statin-induced ERK1/2, Akt, and eNOS phosphorylation.
Topics: 5'-Nucleotidase; Adenosine; Animals; Atorvastatin; Butadienes; Enzyme Inhibitors; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 3; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Nitriles; Phosphodiesterase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Receptors, Purinergic P1; Theophylline | 2007 |
Anticonvulsant effect of A1 but not A2A adenosine receptors of piriform cortex in amygdala-kindled rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amygdala; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Kindling, Neurologic; Male; Microinjections; Models, Anatomic; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Triazines; Triazoles | 2007 |
Role of adenosine in regulating the heterogeneity of skeletal muscle blood flow during exercise in humans.
Topics: Adenosine; Adult; Blood Flow Velocity; Blood Pressure; Exercise; Female; Heart Rate; Humans; Infusions, Intravenous; Isometric Contraction; Positron-Emission Tomography; Purinergic P1 Receptor Antagonists; Quadriceps Muscle; Receptors, Purinergic P1; Regional Blood Flow; Theophylline | 2007 |
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2008 |
Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.
Topics: 4-Aminopyridine; Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hyperemia; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Time Factors; Triterpenes; Vasodilation | 2008 |
Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor.
Topics: Acetamides; Adenine Nucleotides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens, Surface; Arginase; Cyclic AMP; Cytokines; Dendritic Cells; Gene Expression; Gene Expression Profiling; Interleukin-12; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrites; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Signal Transduction; Theophylline | 2008 |
N-methyl-D-aspartic acid causes relaxation of porcine retinal arterioles through an adenosine receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine Triphosphate; Animals; Arterioles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrolysis; Muscle, Smooth, Vascular; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Retinal Artery; Swine; Theophylline; Vasodilation | 2008 |
Nitric oxide modulates the discharge rate of basal forebrain neurons.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Diagonal Band of Broca; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Extracellular Space; Male; Microdialysis; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Physical Stimulation; Preoptic Area; Prosencephalon; Rats; Rats, Wistar; Substantia Innominata; Theophylline; Touch Perception; Urethane | 2008 |
Intermittent adenosine at the beginning of reperfusion does not trigger cardioprotection.
Topics: Adenosine; Animals; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Vasodilator Agents | 2009 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
Correlation of intrinsic optical signal, cerebral blood flow, and evoked potentials during activation of rat somatosensory cortex.
Topics: Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Evoked Potentials, Somatosensory; Hindlimb; Male; Optics and Photonics; Pia Mater; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Theophylline; Vasodilator Agents | 2008 |
Microdialysis elevation of adenosine in the basal forebrain produces vigilance impairments in the rat psychomotor vigilance task.
Topics: Adenosine; Animals; Appetitive Behavior; Arousal; Attention; Microdialysis; Prosencephalon; Psychomotor Performance; Rats; Rats, Inbred F344; Reaction Time; Sleep; Theophylline | 2008 |
Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Biological Clocks; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Fourier Analysis; Hippocampus; Hypoxia; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Thioinosine; Time Factors; Triazines; Triazoles | 2009 |
Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus.
Topics: Adenosine; Adenosine Kinase; Animals; Animals, Newborn; Astrocytes; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Hippocampus; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Seizures; Synapses; Theophylline; Time Factors; Tubercidin | 2009 |
Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Biomarkers; Cerebral Cortex; Dose-Response Relationship, Drug; Gene Expression Regulation; Limbic System; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Theophylline; Ventral Tegmental Area | 2009 |
ATP-induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine.
Topics: Adenosine; Adenosine Triphosphate; Adult; Blood Flow Velocity; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indomethacin; Infusions, Intra-Arterial; Lower Extremity; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Regional Blood Flow; RNA, Messenger; Signal Transduction; Theophylline; Vasodilation; Young Adult | 2009 |
Activation of NTS A2a adenosine receptors differentially resets baroreflex control of renal vs. adrenal sympathetic nerve activity.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenal Glands; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Heart Rate; Kidney; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Solitary Nucleus; Sympathetic Nervous System; Theophylline; Triazines; Triazoles | 2009 |
Elucidation in the rat of the role of adenosine and A2A-receptors in the hyperaemia of twitch and tetanic contractions.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Carbon Dioxide; Electric Stimulation; Femoral Artery; Hydrogen-Ion Concentration; Hyperemia; Isometric Contraction; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Oxygen; Rats; Rats, Wistar; Receptor, Adenosine A2A; Regional Blood Flow; Sciatic Nerve; Theophylline; Time Factors; Triazines; Triazoles; Vasodilation | 2009 |
Interaction of hydrocortisone with ATP and adenosine on nerve-mediated contractions of frog skeletal muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Hydrocortisone; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana ridibunda; Theophylline; Time Factors | 2009 |
Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.
Topics: Adenosine; Animals; Biological Transport; Hypoglycemic Agents; In Vitro Techniques; Male; Metformin; Myocardial Infarction; Myocardial Reperfusion Injury; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Thioinosine | 2009 |
Roles of purines in synaptic modulation evoked by hypercapnia in isolated spinal cord of neonatal rat in vitro.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Animals, Newborn; Electrophysiology; Evoked Potentials; Extracellular Space; Female; Hypercapnia; In Vitro Techniques; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Reflex; Spinal Cord; Synaptic Transmission; Theophylline | 2009 |
Adenosine contributes to blood flow regulation in the exercising human leg by increasing prostaglandin and nitric oxide formation.
Topics: Adenosine; Adult; Analysis of Variance; Cohort Studies; Exercise; Humans; Hyperemia; Indomethacin; Leg; Male; Muscle, Skeletal; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Reference Values; Regional Blood Flow; Sensitivity and Specificity; Theophylline; Vasodilation; Young Adult | 2009 |
Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Analgesics, Opioid; Animals; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle, Smooth; Naloxone; Narcotic Antagonists; Narcotics; Phenethylamines; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinidine; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Purinergic P2; Substance Withdrawal Syndrome; Theobromine; Theophylline | 2009 |
Photochemical decomposition of dipyridamole in aqueous solution and the utilization of citrate-theophylline-adenosine-dipyridamole anticoagulant for monitoring of heparin.
Topics: Adenosine; Anticoagulants; Citric Acid; Clinical Laboratory Techniques; Dipyridamole; Heparin; Humans; Light; Photochemistry; Solutions; Theophylline; Water | 2010 |
Theophylline attenuates hippocampal blood flow responses induced by tooth pulp stimulation in rats.
Topics: Adenosine; Afferent Pathways; Animals; Cerebral Arteries; Cerebrovascular Circulation; Dental Pulp Cavity; Disease Models, Animal; Electric Stimulation; Hippocampus; Injections, Intraperitoneal; Laser-Doppler Flowmetry; Male; Nociceptors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Toothache; Vasodilator Agents | 2009 |
The effect of anticoagulants on the quality and biological efficacy of platelet-rich plasma.
Topics: Adenosine; Adolescent; Adult; Anticoagulants; Blood Platelets; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Citric Acid; Dipyridamole; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Heparin; Humans; Male; Microscopy, Electron, Transmission; P-Selectin; Platelet-Rich Plasma; Stromal Cells; Theophylline; Transforming Growth Factor beta1; Young Adult | 2009 |
Differential effects of adenosine antagonists in two models of parkinsonian tremor.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Synergism; Jaw; Male; Parkinsonian Disorders; Pimozide; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Theophylline; Tremor; Triazoles | 2009 |
Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning.
Topics: Adenosine; Animals; Animals, Newborn; Cells, Cultured; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lysophospholipids; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Receptors, Purinergic P1; Recovery of Function; Signal Transduction; Sphingosine; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2009 |
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relationship, Drug; Enteric Nervous System; Gastrointestinal Motility; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Intestinal Secretions; Male; Mecamylamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neural Inhibition; Neurogenic Bowel; Neurokinin-1 Receptor Antagonists; Nicotinic Antagonists; Piperidines; Propane; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Histamine H2; Receptors, Neurokinin-1; Reflex; Theophylline; Xanthines | 2009 |
Adenosine A1 receptor blockage mediates theophylline-associated seizures.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Behavior, Animal; Body Temperature; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Lew; Seizures; Theophylline; Tubercidin | 2010 |
Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Adult; Apoptosis; Caspase 3; CD11c Antigen; Cell Differentiation; Dendritic Cells; Granulocyte-Macrophage Colony-Stimulating Factor; HLA-DR Antigens; Humans; Interleukin-4; Male; Monocytes; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptors, Purinergic P1; Recombinant Proteins; RNA, Small Interfering; Rolipram; Theophylline; Xanthines | 2009 |
Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dilazep; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Muscle Contraction; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Vasodilator Agents | 2010 |
A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatic Artery; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
Hypoxia enhances the relaxing influence of perivascular adipose tissue in isolated mice aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adipose Tissue; Animals; Aorta, Thoracic; Arteries; Cell Hypoxia; Dinoprost; Glyburide; Guanylate Cyclase; Male; Mice; Norepinephrine; Potassium; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfides; Tetraethylammonium; Theophylline; Vasodilation | 2010 |
Metabolic regulation of coronary vascular tone: role of hydrogen peroxide, purinergic components, and angiotensin.
Topics: Adenosine; Adenosine Diphosphate; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arterioles; Catalase; Coronary Vessels; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Lactic Acid; Male; Myocytes, Cardiac; Oxygen; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Superoxides; Tetrazoles; Theophylline; Vascular Resistance; Vasoconstriction; Vasodilation | 2010 |
Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.
Topics: Adenosine; Disulfides; Humans; Ligands; Protein Denaturation; Protein Stability; Receptors, Adenosine A2; Receptors, G-Protein-Coupled; Theophylline | 2010 |
Endogenous adenosine A1 receptor activation underlies the transient post-ischemic rhythmic delta EEG activity.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Delta Rhythm; Disease Models, Animal; Electrocardiography; Electroencephalography; Heart Rate; Ischemic Attack, Transient; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Statistics, Nonparametric; Theophylline; Xanthines | 2011 |
Monitoring treatments with unfractionated heparin: CTAD must be used instead of citrate as the anticoagulant solution when using partial-draw collection tubes. Results of a multicenter evaluation.
Topics: Adenosine; Anticoagulants; Blood Coagulation Tests; Blood Specimen Collection; Citrates; Dipyridamole; Drug Monitoring; Heparin; Humans; Theophylline | 2010 |
Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bradycardia; Endothelium, Vascular; Female; Hypoxia; Male; Muscle, Skeletal; Pregnancy; Prenatal Exposure Delayed Effects; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Theophylline; Vasodilation; Xanthines | 2010 |
Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants.
Topics: Adenosine; Animals; Chorionic Villi; Enzyme-Linked Immunosorbent Assay; Female; Hypoxia; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2010 |
Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.
Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Amino Acids; Animals; Baclofen; Barium; Bee Venoms; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cesium; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Potassium Channel Blockers; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Theophylline; Xanthenes | 2011 |
Remote ischaemic preconditioning by brief hind limb ischaemia protects against renal ischaemia-reperfusion injury: the role of adenosine.
Topics: Adenosine; Animals; Hindlimb; Ischemic Preconditioning; Kidney; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Theophylline | 2011 |
Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice.
Topics: Adenosine; Analysis of Variance; Animals; Astrocytes; Electrophysiology; Exocytosis; Female; Hippocampus; Male; Memory; Mice; Mice, Transgenic; Neuronal Plasticity; Receptor, Adenosine A1; Sleep Deprivation; SNARE Proteins; Synapses; Theophylline | 2011 |
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Hydroxy Acids; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion Injury; Superoxides; Tetrazoles; Theophylline | 2011 |
[Effects of anticoagulants and storage temperature on immature platelet fraction % (IPF%) values in stored samples measured by the automated hematology analyzer, XE-5000--utility of CTAD-anticoagulation and room temperature storage].
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Preservation; Citric Acid; Dipyridamole; Female; Hematologic Tests; Humans; Male; Middle Aged; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Sodium Fluoride; Solutions; Temperature; Theophylline | 2011 |
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial Infarction; Naloxone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Opioid; Receptors, Purinergic P1; Theophylline; Time Factors | 2012 |
The interactions of nitric oxide and adenosine on penicillin-induced epileptiform activity in rats.
Topics: Action Potentials; Adenosine; Animals; Brain Waves; Disease Models, Animal; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Theophylline | 2011 |
Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A(1) receptors.
Topics: Adenosine; Animals; Arctic Regions; Body Temperature; Body Temperature Regulation; Brain; Hibernation; Injections, Intraventricular; Oxygen Consumption; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Sciuridae; Seasons; Telemetry; Theophylline; Xanthines | 2011 |
Inducing hibernation in the arctic ground squirrel.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Arctic Regions; Brain; Hibernation; Receptor, Adenosine A1; Sciuridae; Seasons; Theophylline | 2011 |
Platelet-stored angiogenesis factors: clinical monitoring is prone to artifacts.
Topics: Adenosine; Adult; Aged; Analytic Sample Preparation Methods; Angiogenic Proteins; Artifacts; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Platelets; Citric Acid; Dipyridamole; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Neovascularization, Pathologic; Plasma; Platelet Factor 4; Theophylline; Thymidine Phosphorylase; Vascular Endothelial Growth Factor A | 2011 |
Comparison of platelet clumping and complete blood count results with Sysmex XT-2000iV in feline blood sampled on EDTA or EDTA plus CTAD (citrate, theophylline, adenosine and dipyridamole).
Topics: Adenosine; Animals; Blood Cell Count; Cat Diseases; Cats; Citric Acid; Dipyridamole; Edetic Acid; Flow Cytometry; Platelet Aggregation; Platelet Count; Theophylline; Thrombocytopenia | 2011 |
Presynaptic inhibition of GABAergic synaptic transmission by adenosine in mouse hypothalamic hypocretin neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neural Inhibition; Neuropeptides; Orexins; Patch-Clamp Techniques; Presynaptic Terminals; Purinergic Antagonists; Synaptic Transmission; Theobromine; Theophylline; Valine | 2012 |
Regulation of subcutaneous adipose tissue blood flow during exercise in humans.
Topics: Adenosine; Blood Pressure; Exercise; Female; Heart Rate; Humans; Leg; Muscle, Skeletal; Positron-Emission Tomography; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Rest; Subcutaneous Fat; Theophylline; Young Adult | 2012 |
Opposing effects of ATP and adenosine on barrier function of rat coronary microvasculature.
Topics: Actin Cytoskeleton; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cadherins; Cells, Cultured; Coronary Vessels; Edema, Cardiac; Endothelial Cells; Male; Myocardium; Permeability; Protein Transport; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Venules | 2012 |
Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Rana ridibunda; Receptors, Purinergic P1; Signal Transduction; Suramin; Theophylline | 2011 |
Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine.
Topics: Adenosine; Animals; Astrocytes; Cerebral Cortex; Excitatory Postsynaptic Potentials; Extracellular Fluid; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptor, Adenosine A1; Sleep Deprivation; Synaptic Transmission; Theophylline; Vesicle-Associated Membrane Protein 2; Wakefulness | 2012 |
Activation of NTS A(1) adenosine receptors inhibits regional sympathetic responses evoked by activation of cardiopulmonary chemoreflex.
Topics: Adenosine; Animals; Biguanides; Blood Pressure; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Dose-Response Relationship, Drug; Feedback, Physiological; Heart Rate; Lung; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Theophylline | 2012 |
Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biophysics; Brain; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nerve Fibers; Neural Inhibition; Potassium Chloride; Quinoxalines; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 2012 |
Heterosynaptic long-term depression mediated by ATP released from astrocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens; Astrocytes; Biophysics; Calcium; Calcium Signaling; Cells, Cultured; Channelrhodopsins; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Genetic Vectors; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Neurons; Optical Phenomena; Patch-Clamp Techniques; Proteoglycans; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Serine; Theophylline; Time Factors; Transfection | 2013 |
Changes in haematology measurements with the Sysmex XT-2000iV during storage of feline blood sampled in EDTA or EDTA plus CTAD.
Topics: Adenosine; Animals; Blood Cell Count; Cats; Citric Acid; Dipyridamole; Edetic Acid; Specimen Handling; Theophylline | 2013 |
Cortical spreading depression-induced preconditioning in mouse neocortex is lamina specific.
Topics: Adenosine; Animals; Brain Waves; Calcium; Carbon Dioxide; Cell Hypoxia; Cortical Spreading Depression; Dipyridamole; Dose-Response Relationship, Drug; Glucose; Ischemic Preconditioning; Membrane Potentials; Mice; Neocortex; Neural Inhibition; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Theophylline | 2013 |
Acute intravenous infusion of an adenosine regulating agent improves left ventricular function in dogs with advanced heart failure.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Deoxyribonucleosides; Dogs; Heart Failure; Hemodynamics; Infusions, Intravenous; Purinergic P1 Receptor Antagonists; Theophylline; Ventricular Function, Left | 2013 |
Remote cardioprotection by transfer of coronary effluent from ischemic preconditioned rabbit heart preserves mitochondrial integrity and function via adenosine receptor activation.
Topics: Adenosine; Animals; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Mitochondria; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Reactive Oxygen Species; Receptors, Purinergic P1; Theophylline | 2014 |
Adenosine receptor inhibition attenuates the decrease in cutaneous vascular conductance during whole-body cooling from hyperthermia.
Topics: Adenosine; Adult; Body Temperature Regulation; Female; Fever; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Reflex; Regional Blood Flow; Skin; Theophylline; Vasoconstriction; Vasodilation; Young Adult | 2014 |
Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine.
Topics: Action Potentials; Adenosine; Alcohols; Animals; Brain Waves; Electroencephalography; Excitatory Postsynaptic Potentials; Extracellular Fluid; Hippocampus; Homeostasis; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Movement Disorders; Neurons; Purinergic P1 Receptor Antagonists; Sleep Deprivation; Sleep Stages; Theophylline; Thioinosine; Time Factors; Wakefulness | 2014 |
The influence of four different anticoagulants on dynamic light scattering of platelets.
Topics: Adenine; Adenosine; Anticoagulants; Blood Platelets; Cell Size; Chelating Agents; Citrates; Dipyridamole; Edetic Acid; Glucose; Humans; Light; Phosphates; Platelet-Rich Plasma; Scattering, Radiation; Theophylline | 2014 |
Adenosinergic regulation of the cardiovascular system in the red-eared slider Trachemys scripta.
Topics: Adenosine; Animals; Bradycardia; Cardiovascular System; Heart Rate; Hemodynamics; Pulmonary Circulation; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Reptilian Proteins; Theophylline; Turtles; Vasodilation; Vasodilator Agents | 2014 |
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Atrial Fibrillation; Bradycardia; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; Fibrosis; Heart Conduction System; Heart Failure; Receptor, Adenosine A1; Sinoatrial Node; Tachycardia; Theophylline; Up-Regulation; Voltage-Sensitive Dye Imaging; Xanthines | 2014 |
[Roles of adenosine and cytokines in the prostate tissue of rats with acute bacterial prostatitis].
Topics: Adenosine; Animals; Escherichia coli O157; Interleukin-10; Male; Prostate; Prostatitis; Random Allocation; Rats; Rats, Wistar; Theophylline; Tumor Necrosis Factor-alpha | 2014 |
Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Coronary Circulation; Free Radical Scavengers; Glyburide; Heart; Hydrogen Peroxide; Hyperemia; In Vitro Techniques; KATP Channels; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Potassium Channel Blockers; Pyrimidines; Receptors, Purinergic P1; Theophylline; Triazoles | 2014 |
The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anticonvulsants; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Pentylenetetrazole; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Seizures; Theophylline; Yohimbine | 2014 |
Adenosine signaling in reserpine-induced depression in rats.
Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Brain; Caffeine; Depressive Disorder; Dose-Response Relationship, Drug; Flavins; Male; Neuropsychological Tests; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Random Allocation; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reserpine; Swimming; Theophylline | 2015 |
An interaction between glucagon-like peptide-1 and adenosine contributes to cardioprotection of a dipeptidyl peptidase 4 inhibitor from myocardial ischemia-reperfusion injury.
Topics: Adenosine; Adenosine Deaminase; Animals; Apoptosis; Cardiotonic Agents; Cyclic AMP Response Element-Binding Protein; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dogs; Extracellular Signal-Regulated MAP Kinases; Female; Glucagon-Like Peptide 1; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hemodynamics; Myocardial Reperfusion Injury; Piperidines; Protein Binding; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Antagonists; Theophylline; Uracil | 2015 |
Translating drug-induced hibernation to therapeutic hypothermia.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Body Temperature; CA1 Region, Hippocampal; Cell Death; Disease Models, Animal; Heart Arrest; Heart Rate; Hibernation; Hypothermia, Induced; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Temperature; Theophylline | 2015 |
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Interleukin-1beta; Medicine, Chinese Traditional; Mice; Monoterpenes; Motor Activity; Paclitaxel; Pain Measurement; Theobromine; Theophylline; Xanthines | 2015 |
[The study of anticoagulants selection in platelet-rich plasma preparation].
Topics: Adenosine; Anticoagulants; Blood Platelets; Citrates; Citric Acid; Dipyridamole; Drug Combinations; Glucose; Heparin; Platelet Activation; Platelet-Rich Plasma; Theophylline; Transforming Growth Factor beta1 | 2015 |
Efficacy of theophylline in patients affected by low adenosine syncope.
Topics: Adenosine; Adult; Aged; Dose-Response Relationship, Drug; Electrocardiography; Female; Follow-Up Studies; Forecasting; Heart Rate; Humans; Male; Middle Aged; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Recurrence; Retrospective Studies; Syncope; Theophylline; Young Adult | 2016 |
ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform.
Topics: Adenosine; Aptamers, Nucleotide; Benzidines; Chromogenic Compounds; Colorimetry; Enzyme Assays; Horseradish Peroxidase; Humans; Streptavidin; Theophylline | 2016 |
Comparison of different anticoagulant associations on haemostasis and biochemical analyses in feline blood specimens.
Topics: Adenosine; Animals; Anticoagulants; Blood Specimen Collection; Cats; Citric Acid; Dipyridamole; Flow Cytometry; Hemostasis; Platelet Aggregation; Reproducibility of Results; Specimen Handling; Theophylline | 2017 |
Effects of ATP and adenosine on contraction amplitude of rat soleus muscle at different temperatures.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Hypothermia; Male; Muscle Contraction; Muscle, Skeletal; Nicotinic Antagonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Temperature; Theophylline; Tubocurarine | 2017 |
Evaluation of CTAD (citrate-theophylline-adenosine-dipyridamole) as a universal anticoagulant in dogs.
Topics: Adenosine; Animals; Anticoagulants; Blood Cell Count; Blood Coagulation; Blood Specimen Collection; Citric Acid; Dipyridamole; Dogs; Platelet Aggregation; Prospective Studies; Reference Values; Theophylline | 2017 |
Adenosinergic signaling inhibits oxalate transport by human intestinal Caco2-BBE cells through the A
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine Triphosphate; Amino Acid Transport Systems; Biological Transport; Caco-2 Cells; Humans; Hyperoxaluria; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Kidney Calculi; Oxalates; Receptor, Adenosine A2B; Risk Factors; Signal Transduction; Symporters; Theophylline; Type C Phospholipases | 2018 |
Prediction of self-assembly of adenosine analogues in solution: a computational approach validated by isothermal titration calorimetry.
Topics: Adenosine; Caffeine; Calorimetry; Dimerization; Models, Molecular; Molecular Structure; Solvents; Structure-Activity Relationship; Surface Properties; Theophylline; Thermodynamics; Water | 2019 |
Efficacy of theophylline in patients with syncope without prodromes with normal heart and normal ECG.
Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Dose-Response Relationship, Drug; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Purinergic P1 Receptor Antagonists; Syncope; Theophylline; Time Factors; Treatment Outcome; Young Adult | 2019 |
Lipotoxicity-associated inflammation is prevented by guarana (
Topics: Adenosine; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperlipidemias; Inflammation; Lymphocytes; Male; Rats; Rats, Wistar; Simvastatin; Theobromine; Theophylline | 2021 |
Effect and Mechanism of Phosphodiesterase Inhibitors on Trabecular Outflow.
Topics: Adenosine; Blotting, Western; Cells, Cultured; Dipyridamole; Humans; Matrix Metalloproteinases; Nitric Oxide; Phosphodiesterase Inhibitors; Theophylline; Trabecular Meshwork | 2019 |
[Theophylline adenosine dipyridamole (CTAD) and citrate evaluation to survey unfractionated heparin treatment: a delayed centrifugation validation for anti-Xa measurement?].
Topics: Adenosine; Anticoagulants; Blood Coagulation Tests; Blood Preservation; Blood Specimen Collection; Centrifugation; Chemical Fractionation; Citric Acid; Dipyridamole; Drug Monitoring; Factor Xa; Factor Xa Inhibitors; Heparin; Humans; Partial Thromboplastin Time; Theophylline; Thrombin Time; Time Factors | 2020 |
Interplay of the adenosine system and NO in control of renal haemodynamics and excretion: Comparison of normoglycaemic and streptozotocin diabetic rats.
Topics: Adenosine; Animals; Arterial Pressure; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Renal Circulation; Renal Elimination; Streptozocin; Theophylline | 2020 |
A New Series of 1,3-Dimethylxanthine Based Adenosine A
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Molecular Docking Simulation; Parkinson Disease; Rats; Receptor, Adenosine A2A; Structure-Activity Relationship; Theophylline | 2021 |
GLP-1 vasodilatation in humans with coronary artery disease is not adenosine mediated.
Topics: Adenosine; Aged; Aged, 80 and over; Coronary Artery Disease; Coronary Vessels; Female; Glucagon-Like Peptide 1; Humans; Male; Middle Aged; Purinergic P1 Receptor Antagonists; Signal Transduction; Theophylline; Vasodilation; Vasodilator Agents | 2021 |
The Impact of the Anticoagulant Type in Blood Collection Tubes on Circulating Extracellular Plasma MicroRNA Profiles Revealed by Small RNA Sequencing.
Topics: Adenosine; Adult; Anticoagulants; Blood Specimen Collection; Circulating MicroRNA; Citrates; Dipyridamole; Edetic Acid; Female; Hemolysis; Humans; Male; MicroRNAs; Sequence Analysis, RNA; Sodium Citrate; Theophylline | 2022 |
Cross-Binding of Four Adenosine/ATP Aptamers to Caffeine, Theophylline, and Other Methylxanthines.
Topics: Adenosine; Adenosine Triphosphate; Aptamers, Nucleotide; Caffeine; Theophylline | 2023 |
Cross-Binding of Adenosine by Aptamers Selected Using Theophylline.
Topics: Adenosine; Aptamers, Nucleotide; Caffeine; Nucleotide Motifs; Theophylline | 2023 |