theophylline has been researched along with 8-cyclopentyl-1,3-dimethylxanthine in 236 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (2.54) | 18.7374 |
| 1990's | 122 (51.69) | 18.2507 |
| 2000's | 88 (37.29) | 29.6817 |
| 2010's | 20 (8.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F | 1 |
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Bey, P; Demeter, DA; Dudley, MW; Lentz, NL; Meng, EC; Ogden, AM; Peet, NP; Weintraub, HJ | 1 |
| Daly, JW; Padgett, WL; Shamim, MT; Ukena, D | 1 |
| Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S | 1 |
| Catarzi, D; Cecchi, L; Colotta, V; Filacchioni, G; Lucacchini, A; Martini, C; Trincavelli, L; Varano, F | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Koyama, I; Sekino, Y | 1 |
| Garaschuk, O; Kovalchuk, Yu; Krishtal, O | 1 |
| Breyer, MD; Noland, TD; Snyder, HM | 1 |
| Fredholm, BB; Gerwins, P | 1 |
| Bowmer, CJ; Collis, MG; Munsey, TS; Panjehshahin, MR; Yates, MS | 1 |
| Jin, ZL; Lee, TF; Wang, LC | 1 |
| Bauman, LA; Gribkoff, VK | 1 |
| Baumgold, J; Jacobson, KA; Nikodijevic, O | 1 |
| Boissard, CG; Gribkoff, VK; Lindner, MD | 1 |
| Lambert, NA; Teyler, TJ | 1 |
| Barajas-Lopez, C; North, RA; Surprenant, A | 1 |
| Brown, SJ; Evenden, JL; Gill, R; Iversen, SD; Richardson, PJ | 1 |
| Bissonnette, JM; Reddington, M | 1 |
| Daly, JW; Jacobson, KA; Nikodijević, O; Sarges, R | 1 |
| Lee, TF; Wang, LC; Wang, XL | 1 |
| Bauman, LA; Gribkoff, VK; VanderMaelen, CP | 1 |
| Gustafsson, LE; Hedqvist, P; Lindbom, L; Ohlén, A; Persson, MG | 1 |
| Pilditch, M; Radulovacki, M; Ticho, S; Virus, RM | 1 |
| Dunér-Engström, M; Fredholm, BB | 1 |
| Bowmer, CJ; Collis, MG; Kellett, R; Yates, MS | 1 |
| Brod, I; Bucher, B; Illes, P; Rickmann, H; Stoclet, JC | 1 |
| Dragunow, M; Robertson, HA | 1 |
| Klishin, A; Krishtal, O; Lozovaya, N | 2 |
| Huguenard, JR; Ulrich, D | 1 |
| Appel, S; Danhof, M; IJzerman, AP; Langemeijer, MW; Mathôt, RA | 1 |
| Dragunow, M; Young, D | 1 |
| Osmanović, SS; Pan, WJ; Shefner, SA | 1 |
| Cazin, L; Mei, YA; Vaudry, H | 1 |
| Nagy, LE | 2 |
| Brooker, RW; Frisella, WA; Mitchell, HL; Yoon, KW | 1 |
| Florio, C; Rosati, AM; Traversa, U; Vertua, R | 2 |
| Engelstein, ED; Lerman, BB | 1 |
| Linden, J; Luthin, DR | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| Barnabei, O; Lucchi, R; Poli, A; Traversa, U | 1 |
| Manabe, T; Manzoni, OJ; Nicoll, RA | 1 |
| Abdul Majid, M; Akbar, M; Kondo, Y; Okajima, F; Sho, K; Tomura, H | 1 |
| Delle Donne, KT; Sonsalla, PK | 1 |
| Camborde, F; Caussade, F; Cloarec, A; Güngör, T; Hertz, F; Malabre, P; Meignen, J; Teulon, JM; Virone-Oddos, A | 1 |
| Collier, B; Tandon, A | 1 |
| de Carolis, AS; Pèzzola, A; Popoli, P | 1 |
| Crosson, CE; DeBenedetto, R; Gidday, JM | 1 |
| Adén, U; Bona, E; Fredholm, BB; Hagberg, H; Lindström, K | 1 |
| Choi, DW; Lobner, D | 1 |
| Barrie, AP; Nicholls, DG | 1 |
| Lucchi, R; Poli, A; Traversa, U; Zottini, M | 1 |
| Appel, S; Danhof, M; IJzerman, AP; Mathôt, RA; Soudijn, W; van Schaick, EA | 1 |
| Hurt, CM; Pelleg, A; Wang, L; Xu, J | 1 |
| David, J; Joseph, T; Kulkarni, C | 2 |
| Briggs, JP; Lorenz, JN; Schnermann, J; Weihprecht, H | 1 |
| Klishin, A; Krishtal, O; Lozovaya, N; Miras-Portugal, MT; Pintor, J | 1 |
| Andersson, KB; Blomhoff, HK; Christoffersen, J; Smeland, EB; Stokke, T; Taskén, K | 1 |
| Patil, RV; Wax, MB | 1 |
| MacGregor, DG; Miller, WJ; Stone, TW | 1 |
| Bartus, RT; Jacobson, KA; Paul, IA; Von Lubitz, DK | 1 |
| Schofield, PR; Townsend-Nicholson, A | 1 |
| Lutz, PL; Pérez-Pinzón, MA; Rosenthal, M; Sick, TJ | 1 |
| Frisella, WA; Sturm, CD; Yoon, KW | 1 |
| Adams, ME; Fox, AP; Mogul, DJ | 1 |
| Boissard, CG; Gribkoff, VK | 1 |
| Dunwiddie, TV; Lupica, CR; Mitchell, JB | 1 |
| Grover, LM; Teyler, TJ | 1 |
| Heffner, TG; Li, AA; Marek, GJ; Richards, JB; Seiden, LS; Shaughnessy, RA | 1 |
| Lee, KS; Lowenkopf, T | 1 |
| Baskys, A; Wojtowicz, JM; Xiong, H | 1 |
| Klishin, A; Krishtal, O; Lozovaya, N; Tsintsadze, T | 1 |
| Shaban, M; Smith, RA; Stone, TW | 1 |
| Baker, SP; Belardinelli, L; Ruble, J; Scammells, PJ; Shryock, JC; Srinivas, M | 1 |
| Headrick, JP | 1 |
| Breimer, DD; Danhof, M; Ijzerman, AP; Mathoôt, RA; Soudijn, W | 1 |
| Chalfant, CE; Cooper, DR; Coulson, R; Olsson, RA; Proch, PS | 1 |
| Ferré, S; Fuxe, K; Giménez-Llort, L; Martínez, E; Pezzola, A; Popoli, P; Reggio, R | 1 |
| Higgins, MJ; Stone, TW | 1 |
| Fredholm, BB; Jin, S | 1 |
| Hansson, V; Levy, FO; Rolstad, B; Taskén, K; Torgersen, KM; Vaage, JT | 1 |
| Chessell, IP; Humphrey, PP; Michel, AD | 1 |
| Broadley, KJ; Maddock, HL | 1 |
| Chen, YH; Fu, WM; Lee, KF; Liou, JC | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A | 2 |
| Ji, T; Kessey, K; Mogul, DJ; Overstreet, LS; Trommer, BL | 1 |
| Broadley, KJ; Ford, WR | 1 |
| Colley, PA; Overstreet, LS; Pasternak, JF; Slater, NT; Trommer, BL | 1 |
| Ikeda, U; Kurosaki, K; Okada, K; Saito, T; Shimada, K; Shimpo, M | 1 |
| Barr, PM; Cannady, SB; Malinowski, MN; Schmit, KV; Schrock, JW; Wilson, DF | 1 |
| Fujii, S; Ito, K; Kato, H; Kuroda, Y; Sasaki, H; Sekino, Y | 1 |
| Doak, GJ; Reid, AR; Sawynok, J; Zarrindast, MR | 1 |
| Kemmotsu, O; Nakamura, I; Ohta, Y | 1 |
| Daval, JL; Nicolas, F | 1 |
| Brodie, MJ; Ross, FM; Stone, TW | 1 |
| Dumas, TC; Foster, TC | 1 |
| Edwards, FA; Robertson, SJ | 1 |
| Shimegi, S | 1 |
| Nishimura, T | 1 |
| Kimura, M; McCann, SM; Porter, JC; Walczewska, A; Yu, WH | 1 |
| Dormer, RL; McPherson, MA; Pereira, MM | 1 |
| Cui, JG; Linderoth, B; Meyerson, BA; Sollevi, A | 1 |
| Lasater, EM; Pfeiffer-Linn, CL | 1 |
| Nilsson, GE; Sundin, L | 1 |
| Birabil, CG; Marks, GA | 1 |
| Ferré, S; Fuxe, K; Pèzzola, A; Popoli, P; Reggio, R | 1 |
| Alexander, KM; Jarvis, MF; Kowaluk, EA; Lynch, JJ | 1 |
| Bockaert, J; Manzoni, O; Pujalte, D; Williams, J | 1 |
| Beukers, MW; Dalpiaz, A; IJzerman, AP; Schofield, PR; Townsend-Nicholson, A | 1 |
| Dormer, RL; Lloyd Mills, C; McPherson, MA; Pereira, MM | 1 |
| Kaneko, S; Okada, M | 1 |
| Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K | 1 |
| Almaraz, L; Gonzalez, C; Rocher, A | 1 |
| Detmar-Hanna, D; Gerber, JG; Zahniser, NR | 1 |
| Spyer, KM; Thomas, T | 1 |
| Kaneko, S; Kawata, Y; Mizuno, K; Murakami, T; Okada, M; Wada, K | 1 |
| Jurklies, B; Kaelin-Lang, A; Niemeyer, G | 1 |
| Fredholm, BB; Johansson, B; Kuzmin, A; Zvartau, EE | 1 |
| Gatch, MB; Lal, H; Wallis, CJ | 1 |
| Bocking, AD; Brien, JF; Fraher, L; Homan, JH; Watson, CS; White, SE | 1 |
| Diao, L; Dunwiddie, TV; Jacobson, KA | 1 |
| Kitamura, Y; Matsuoka, Y; Ohta, S; Okazaki, M; Sekino, Y; Takata, K; Taniguchi, T | 1 |
| Fujii, S; Ito, Ki; Kaneko, K; Kato, H; Kuroda, Y | 1 |
| Song, WJ; Surmeier, DJ; Tkatch, T | 1 |
| Fujii, S; Ito, KL; Kaneko, K; Kato, H; Kuroda, Y; Sasaki, H; Yamazaki, Y; Yoshioka, M | 1 |
| Starodub, AM; Wood, JD | 1 |
| Fujii, S; Ito, K; Itoh, S; Kato, H; Kuroda, Y; Sasaki, H; Yamazaki, Y | 1 |
| Diamond, JS; Jahr, CE | 1 |
| Borowicz, KK; Czuczwar, SJ; Kleinrok, Z | 1 |
| Becq, F; Bulteau, L; Dérand, R; Dormer, RL; Folli, C; Galietta, LJ; Joffre, M; Jougla, C; McNeilly, CM; Métayé, T; Mettey, Y; Morris, MR; Pereira, MM; Vierfond, JM; Zegarra-Moran, O | 1 |
| Kang, JH; Kang, JS; Kim, BS; Koh, HC; Lee, H; Om, SA; Shin, IC | 1 |
| Arnold, MA; Patterson, SL; Sluka, KA | 1 |
| Kato, F; Shigetomi, E | 1 |
| Davies, DG; Fowler, JC; Gervitz, LM; Lutherer, LO; Pirch, JH | 1 |
| Beraudi, A; Di Iorio, P; Notari, S; Poli, A; Traversa, U; Villani, L; Zaccanti, F | 1 |
| Shiomi, H; Tamura, Y | 1 |
| Okada, Y; Sakurai, T; Takata, T; Yang, B; Yokono, K | 1 |
| Bjorvatn, B; Ursin, R | 1 |
| Hattori, G; Higashi, H; Matsuyama, S; Niiyama, S; Tanaka, E; Yasumoto, S | 1 |
| Dall'Igna, OP; Dietrich, MO; Hoffmann, A; Lara, DR; Neto, W; Souza, DO; Vendite, D | 1 |
| Dormer, RL; McNeilly, CM; McPherson, MA; Morris, RM; Pereira, MM; Russell, D; Stratford, FL | 1 |
| Arase, S; Fukui, K; Li, M; Marubayashi, A; Nakaya, Y | 1 |
| Cassiman, JJ; Segal, A; Van Driessche, W; Vankeerberghen, A; Webe, WM | 1 |
| Custer, EE; Dayanithi, G; Lemos, JR; Wang, G | 1 |
| Harayama, H; Kato, S | 1 |
| Fowler, JC; Gervitz, LM; Nalbant, D; Williams, SC | 1 |
| Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Popoli, P; Solinas, M; You, ZB | 1 |
| Crosson, CE; Shearer, TW | 1 |
| Fowler, JC; Gervitz, LM; Hamilton, ME; Lutherer, LO | 1 |
| Lobner, D | 1 |
| Hirsh, JK; Searl, TJ; Silinsky, EM | 1 |
| Rubaj, A; Sieklucka-Dziuba, M; Zgodziński, W | 1 |
| Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
| Cunha, RA; Dall'Igna, OP; Dall'lgna, OP; Lara, DR; Porciúncula, LO; Souza, DO | 1 |
| Aandahl, EM; Aukrust, P; Frøland, SS; Holm, AM; Müller, F; Taskén, K | 1 |
| Fowler, JC; Gervitz, LM; Hamilton, ME; Walker, JA | 1 |
| Davies, DG; Fowler, JC; Gervitz, LM; Omidvar, K | 1 |
| Kimura, M; Saitoh, N; Takahashi, T | 1 |
| Antoniou, K; Ferre, S; Goldberg, SR; Highkin, JL; Hockemeyer, J; Justinova, Z; Munzar, P; Pappas, LA; Segal, PN; Solinas, M | 1 |
| Ferré, S; Goldberg, SR; Hockemeyer, J; Popoli, P; Quarta, D; Solinas, M; You, ZB | 1 |
| Etherington, LA; Frenguelli, BG | 1 |
| Ho, CM; Ho, ST; Peng, SC; Su, CK; Tsai, SK | 1 |
| Allen, G; Aumeerally, N; Sawynok, J | 1 |
| Fuxe, K; Schwarcz, R; Wu, HQ | 1 |
| Asztély, F; Cronberg, T; Fredholm, BB; Olsson, T; Rytter, A; Smith, ML; Wieloch, T | 1 |
| Cordis, GA; Das, DK; Das, S; Maulik, N | 1 |
| Herrero, JF; Ramos-Zepeda, G; Rosenow, S; Schröder, W | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Sato, K | 1 |
| Borycz, J; Ciruela, F; Ferré, S; Franco, R; Goldberg, SR; Hockemeyer, J; Lluis, C; Patkar, K; Quarta, D; Solinas, M; Woods, AS | 1 |
| Ceña, V; Fariñas, I; González-García, C; Martín, ED; Milán, M | 1 |
| Galligan, JJ; Ren, J | 1 |
| Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Müller, CE; Schindler, CW; Tella, SR; Thorndike, EB | 1 |
| de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA | 1 |
| Buño, W; Martín, ED | 1 |
| Arrigoni, E; Crocker, AJ; Greene, RW; Saper, CB; Scammell, TE | 1 |
| Amico, MC; Morrone, LA; Palmery, M; Romanelli, L; Tucci, P; Valeri, P | 2 |
| Monden, M; Nakamura, A; Shintani, M; Shiomi, H; Tamura, Y | 1 |
| Herrera, S; Kasza, K; Mendelson, WB; Szafran, MJ; Tung, A | 1 |
| Fujii, S; Hozumi, Y; Kaneko, K; Kato, H; Kudo, Y; Li, J; Miyakawa, H; Yamazaki, Y | 1 |
| Boeck, CR; Bronzatto, MJ; Kroth, EH; Vendite, D | 1 |
| Akasu, T; Gu, JW; Hasuo, H; Takeya, M | 1 |
| Crosson, CE; Sloan, CF; Yates, PW | 1 |
| Atwood, HL; Cheung, U; Zucker, RS | 1 |
| Holý, A; Kmonícková, E; Potmesil, P; Zídek, Z | 1 |
| Fujikawa, H; Nagata, T; Nishizaki, T; Sai, K; Saito, M; Yamamoto, H; Yamamoto, S; Yamamura, T; Yang, D | 1 |
| Brown, CH; Bull, PM; Ludwig, M; Russell, JA | 1 |
| Feng, JL; Li, GP; Pu, ZJ; Wu, LF | 1 |
| Fang, X; Gao, N; Hu, HZ; Liu, S; Wang, GD; Wang, XY; Wood, JD; Xia, Y | 1 |
| Brown, R; Fredholm, BB; Lai, EY; Mrowka, R; Patzak, A; Persson, AE; Persson, PB; Spielmann, N; Steege, A | 1 |
| Childers, SR; Eisenach, JC; Martin, TJ; Misler, J | 1 |
| Gao, C; Gao, N; Hu, HZ; Liu, S; Wood, JD; Xia, Y | 1 |
| Sekino, Y; Yuan, XH; Zhang, J | 1 |
| Borycz, J; Cunha, RA; Ferré, S; Goldberg, SR; Köfalvi, A; Melani, A; Panlilio, L; Pedata, F; Pereira, MF; Rodrigues, RJ | 1 |
| Fathollahi, Y; Mirnajafi-Zadeh, J; Palizvan, MR; Rezvani, ME | 2 |
| Inoue, M; Kudo, Y; Manita, S; Miyakawa, H; Suzuki, T | 1 |
| Battastini, AM; Bavaresco, L; Bernardi, A; Delgado-Cañedo, A; Jacques-Silva, MC; Lenz, G; Wink, MR | 1 |
| Kalinchuk, AV; Kostin, A; Porkka-Heiskanen, T; Stenberg, D | 1 |
| Haglund, MM; Hochman, DW; Meno, JR; Ngai, AC; Winn, HR | 1 |
| Hamilton, JB; Lancaster, DM; Patel, N; Pietersen, AN; Vreugdenhil, M | 1 |
| Boison, D; Dale, N; Etherington, LA; Frenguelli, BG; Irving, AJ; Meechan, L; Patterson, GE | 1 |
| Martini, CN; Plaza, MV; Vila, Mdel C | 1 |
| Fan, W; Kaplan, GB; Klufas, MA; Leite-Morris, KA | 1 |
| Ban, M; Ito, S; Ohta, T; Otsuguro, K | 1 |
| Gass, N; Kalinchuk, AV; Porkka-Heiskanen, T | 1 |
| Jalali, A; Kawa, K; Larsen, C; Trevitt, J | 1 |
| Misra, UK; Pizzo, SV | 1 |
| Barbolina, MV; Cahill, ME; Jones, KA; Penzes, P; Photowala, H; Prakriya, M; Quilliam, LA; Srivastava, DP; Woolfrey, KM; Xie, Z; Yamashita, M | 1 |
| Alhaj, M; Bozarov, A; Christofi, FL; Cooke, HJ; Grants, I; Hassanain, HH; Ren, T; Wang, YZ; Wunderlich, J; Yu, JG | 1 |
| Crozatier, B; Derangeon, M; Duquesnes, N; Lezoualc'h, F; Li, L; Lucas, A; Mateo, P; Métrich, M; Morel, E | 1 |
| Cao, Y; Ling, L; Liu, C; Malhotra, A | 1 |
| Andreasen, M; Hablitz, JJ; Nedergaard, S; Skov, J | 1 |
| Abel, T; Florian, C; Halassa, MM; Haydon, PG; Vecsey, CG | 1 |
| Ferré, S; Goldberg, SR; Panlilio, LV; Schindler, CW; Thorndike, EB; Yasar, S | 1 |
| Drew, KL; Jinka, TR; Tøien, Ø | 1 |
| Rosania, K | 1 |
| Duan, SM; Hu, ZA; Wang, HK; Xia, JX; Xiong, JX; Ye, JN | 1 |
| Dale, N; Haydon, PG; Schmitt, LI; Sims, RE | 1 |
| Searl, TJ; Silinsky, EM | 1 |
| Lindquist, BE; Shuttleworth, CW | 1 |
| Bu, B; Chen, J; Duan, S; Gao, W; He, Y; Li, Y; Tan, Z; Wang, W; Wu, X; Zeng, L; Zhang, X | 1 |
| Gniel, HM; Martin, RL | 1 |
| Clasadonte, J; Halassa, MM; Haydon, PG; McIver, SR; Schmitt, LI | 1 |
| Mansoori, E; Moezi, L; Niknahad, H; Shafaroodi, H | 1 |
| Hanff, TC; Minor, TR | 1 |
| Chen, CR; Chen, JF; Huang, ZL; Luo, YJ; Qu, WM; Sun, Y; Yanagawa, Y; Zhao, X | 1 |
| Kimura, E; Midorikawa, T; Monoi, N; Murakoshi, M; Murata-Matsuno, A; Nakamura, Y; Nishino, H; Oka, K; Sano, T; Sugafuji, T; Sugiyama, K; Uchiyama, A; Urade, Y | 1 |
| Dudka, J; Gawronska-Grzywacz, M; Gieroba, R; Herbet, M; Izdebska, M; Janas, M; Korga, A; Piatkowska-Chmiel, I; Poleszak, E; Serefko, A; Szopa, A; Wosko, S | 1 |
| Andrade-Talavera, Y; Armengol, JA; Arroyo-García, LE; Duque-Feria, P; Flores, G; Pérez-Rodríguez, M; Pérez-Villegas, EM; Prius-Mengual, J; Rodríguez-Moreno, A | 1 |
2 review(s) available for theophylline and 8-cyclopentyl-1,3-dimethylxanthine
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
[Pharmacological aspects of mammalian hibernation: central thermoregulation factors in hibernation cycle].
Topics: Adenosine; Animals; Body Temperature; Body Temperature Regulation; Central Nervous System; Cricetinae; Hibernation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Thyrotropin-Releasing Hormone | 2000 |
234 other study(ies) available for theophylline and 8-cyclopentyl-1,3-dimethylxanthine
| Article | Year |
|---|---|
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines | 1992 |
A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.
Topics: Adenosine; Animals; Dogs; Humans; Molecular Conformation; Molecular Structure; Protein Binding; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines | 1990 |
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines | 1989 |
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines | 1989 |
1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists.
Topics: Animals; Binding, Competitive; Cattle; Cell Line; Cerebral Cortex; Corpus Striatum; Humans; In Vitro Techniques; Purinergic P1 Receptor Antagonists; Quinoxalines; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship | 2000 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Selective inhibition of homosynaptic depression in a tetanized pathway by an adenosine A1 blocker in the CA1 region of rat hippocampal slice.
Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Purinergic Antagonists; Pyramidal Tracts; Rats; Rats, Wistar; Synapses; Theophylline; Time Factors | 1992 |
Adenosine-dependent enhancement by methylxanthines of excitatory synaptic transmission in hippocampus of rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Theophylline | 1992 |
cAMP-dependent protein kinase mediates hydrosmotic effect of vasopressin in collecting duct.
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Isoquinolines; Kidney Tubules, Collecting; Osmosis; Permeability; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Stereoisomerism; Sulfonamides; Theophylline; Vasopressins; Water | 1992 |
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Muscle, Smooth; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Type C Phospholipases; Virulence Factors, Bordetella | 1992 |
Further characterization of the protective effect of 8-cyclopentyl-1,3-dipropylxanthine on glycerol-induced acute renal failure in the rat.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acute Kidney Injury; Adenosine; Animals; Creatinine; Glycerol; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation; Theophylline; Urea | 1992 |
Decrease in cold tolerance of aged rats caused by the enhanced endogenous adenosine activity.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Body Temperature Regulation; Cold Temperature; Lysine; Male; Neck Muscles; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1992 |
Endogenous adenosine contributes to hypoxic synaptic depression in hippocampus from young and aged rats.
Topics: Adenosine; Aging; Animals; Cell Hypoxia; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Nitrogen; Rats; Rats, Inbred F344; Synapses; Theophylline | 1992 |
Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding.
Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Injections, Intraperitoneal; Locomotion; Male; Mice; Receptors, Purinergic; Theophylline; Time Factors; Xanthines | 1992 |
Hypoxia produces cell death in the rat hippocampus in the presence of an A1 adenosine receptor antagonist: an anatomical and behavioral study.
Topics: Animals; Avoidance Learning; Cell Death; Cognition; Hippocampus; Hypoxia; Male; Memory; Motor Activity; Purinergic Antagonists; Pyramidal Tracts; Rats; Rats, Inbred F344; Reference Values; Theophylline | 1992 |
Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Evoked Potentials; Hippocampus; In Vitro Techniques; Membrane Potentials; Quinoxalines; Rats; Synapses; Synaptic Transmission; Theophylline | 1991 |
Adenosine A1 and A2 receptors mediate presynaptic inhibition and postsynaptic excitation in guinea pig submucosal neurons.
Topics: Acetylcholine; Adenosine; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Intestinal Mucosa; Male; Membrane Potentials; Neurons; Norepinephrine; Receptors, Nicotinic; Receptors, Purinergic; Theophylline | 1991 |
Striatal A2 receptor regulates apomorphine-induced turning in rats with unilateral dopamine denervation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Apomorphine; Brain Chemistry; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Oxidopamine; Rats; Receptors, Purinergic; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical; Theophylline | 1991 |
Autoradiographic localization of adenosine A1 receptors in brainstem of fetal sheep.
Topics: Animals; Autoradiography; Brain Stem; Fetus; Kinetics; Neurons; Organ Specificity; Receptors, Purinergic; Sheep; Theophylline; Tritium | 1991 |
Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Injections, Intraperitoneal; Locomotion; Male; Mice; Phenethylamines; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1991 |
Do adenosine antagonists improve cold tolerance by reducing hypothalamic adenosine activity in rats?
Topics: Adenosine Deaminase; Animals; Anterior Hypothalamic Nucleus; Body Temperature Regulation; Cold Temperature; Humans; Male; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Theophylline | 1990 |
The adenosine antagonist 8-cyclopentyltheophylline reduces the depression of hippocampal neuronal responses during hypoxia.
Topics: Action Potentials; Animals; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Purinergic Antagonists; Rats; Receptors, Purinergic; Theophylline | 1990 |
Adenosine modulation of resting vascular tone in rabbit skeletal muscle.
Topics: Adenosine; Animals; Arteries; Arterioles; Dose-Response Relationship, Drug; Microcirculation; Muscles; Rabbits; Theophylline; Vasoconstriction; Vasomotor System; Xanthines | 1990 |
A comparison of the effects of caffeine, 8-cyclopentyltheophylline, and alloxazine on sleep in rats. Possible roles of central nervous system adenosine receptors.
Topics: Animals; Brain; Caffeine; Flavins; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reference Values; Sleep; Sleep Stages; Sleep, REM; Theophylline | 1990 |
Propentofylline and a hydroxy metabolite augment A2-receptor mediated cyclic AMP accumulation and attenuate A1-receptor mediated inhibition of acetylcholine release in the rat hippocampus.
Topics: Acetylcholine; Adenosine; Animals; Cyclic AMP; Dipyridamole; Hippocampus; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Xanthines | 1989 |
Amelioration of glycerol-induced acute renal failure in the rat with 8-cyclopentyl-1,3-dipropylxanthine.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Glycerol; Heart Rate; Inulin; Kidney; Male; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Regional Blood Flow; Theophylline | 1989 |
Subsensitivity of presynaptic adenosine A1-receptors in caudal arteries of spontaneously hypertensive rats.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Electric Stimulation; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Purinergic; Species Specificity; Theophylline; Vasoconstriction | 1989 |
8-Cyclopentyl 1,3-dimethylxanthine prolongs epileptic seizures in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy; Male; Rats; Rats, Inbred Strains; Theophylline | 1987 |
Persistently enhanced ratio of NMDA and non-NMDA components of rat hippocampal EPSC after block of A1 adenosine receptors at increased [Ca2+]o/[Mg2+]o.
Topics: Animals; Calcium; Electrophysiology; Hippocampus; In Vitro Techniques; Ion Channels; Magnesium; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glutamate; Synapses; Theophylline | 1994 |
A1 adenosine receptors differentially regulate the N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated components of hippocampal excitatory postsynaptic current in a Ca2+/Mg(2+)-dependent manner.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Calcium; Hippocampus; In Vitro Techniques; Ion Channels; Magnesium; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synapses; Theophylline | 1995 |
Purinergic inhibition of GABA and glutamate release in the thalamus: implications for thalamic network activity.
Topics: Adenosine; Animals; Bicuculline; Electric Conductivity; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Quinoxalines; Rats; Receptors, Purinergic P1; Synapses; Thalamus; Theophylline | 1995 |
Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline.
Topics: Adenosine; Animals; Blood Pressure; Blood Proteins; Heart Rate; Male; Models, Chemical; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1995 |
Neuronal injury following electrically induced status epilepticus with and without adenosine receptor antagonism.
Topics: Animals; Calbindin 1; Calbindins; Cell Death; Electric Stimulation; Electrophysiology; Fibroblast Growth Factor 2; Immunohistochemistry; Insulin-Like Growth Factor I; Male; Nerve Tissue Proteins; Neurons; Parvalbumins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; S100 Calcium Binding Protein G; Somatostatin; Status Epilepticus; Theophylline | 1995 |
Characterization of the adenosine A1 receptor-activated potassium current in rat locus ceruleus neurons.
Topics: 4-Aminopyridine; Adenosine; Animals; Barium; Dose-Response Relationship, Drug; Glyburide; Locus Coeruleus; Male; Membrane Potentials; Neurons; Potassium Channels; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Theophylline | 1995 |
Inhibitory effect of adenosine on electrical activity of frog melanotrophs mediated through A1 purinergic receptors.
Topics: Action Potentials; Adenosine; alpha-MSH; Animals; Cells, Cultured; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Membrane Potentials; Patch-Clamp Techniques; Pertussis Toxin; Phenylisopropyladenosine; Pituitary Gland; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinazolines; Rana ridibunda; Tachyphylaxis; Theophylline; Triazoles; Virulence Factors, Bordetella | 1994 |
Effects of ethanol-induced changes in adenosine transport on cAMP production in rat hepatocytes.
Topics: Adenosine; Adenosine Deaminase; Animals; Biological Transport, Active; Cells, Cultured; Cyclic AMP; Ethanol; Liver; Rats; Receptors, Glucagon; Receptors, Purinergic P1; Theophylline; Virulence Factors, Bordetella | 1993 |
Attenuation of traumatic cell death by an adenosine A1 agonist in rat hippocampal cells.
Topics: Adenosine; Animals; Brain Injuries; Cell Death; Cells, Cultured; Culture Media; Dizocilpine Maleate; Extracellular Space; Hippocampus; Rats; Rats, Sprague-Dawley; Theophylline | 1995 |
Role of adenosine A1 receptors in inhibition of receptor-stimulated cyclic AMP production by ethanol in hepatocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Cyclic AMP; Drug Interactions; Ethanol; Glucagon; Liver; Male; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1994 |
Strain-related differences in adenosine receptor density and in behavioral sensitivity to adenosine analogs in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Male; Membranes; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Motor Activity; Platelet Aggregation Inhibitors; Radioligand Assay; Receptors, Purinergic P1; Species Specificity; Theophylline | 1994 |
Metabolic determinants of defibrillation. Role of adenosine.
Topics: Adenosine; Animals; Catecholamines; Dogs; Electric Countershock; Lactates; Lactic Acid; Theophylline; Ventricular Fibrillation | 1995 |
Comparison of A4 and A2a binding sites in striatum and COS cells transfected with adenosine A2a receptors.
Topics: Adenosine; Alamethicin; Animals; Binding Sites; Cell Line; Corpus Striatum; Guanosine 5'-O-(3-Thiotriphosphate); Phenethylamines; Potassium Channels; Rats; Receptors, Purinergic P1; Temperature; Theophylline; Transfection | 1995 |
Interaction between adenosine and GABAA receptors on hippocampal neurones.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Barium; Chloride Channels; Drug Combinations; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA; Theophylline | 1994 |
Functional adenosine A1 receptors in goldfish brain: regional distribution and inhibition of K(+)-evoked glutamate release from cerebellar slices.
Topics: Adenosine; Adenylyl Cyclases; Amino Acids; Animals; Calcium; Cerebellum; Colforsin; Cyclic AMP; Glutamates; Glutamic Acid; Goldfish; In Vitro Techniques; Membranes; Potassium; Receptors, Purinergic P1; Theophylline | 1994 |
Release of adenosine by activation of NMDA receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Electric Stimulation; Enkephalins; GABA-B Receptor Antagonists; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Male; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Theophylline | 1994 |
Genistein, an inhibitor of protein tyrosine kinase, is also a competitive antagonist for P1-purinergic (adenosine) receptor in FRTL-5 thyroid cells.
Topics: Adenosine Deaminase; Animals; Cell Line; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Inositol Phosphates; Isoflavones; Kinetics; Phenylisopropyladenosine; Protein-Tyrosine Kinases; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Theophylline; Thyroid Gland; Thyrotropin; Type C Phospholipases | 1994 |
Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; MPTP Poisoning; Receptors, Purinergic P1; Theophylline; Tyrosine 3-Monooxygenase | 1994 |
N6-substituted adenosine receptor agonists. Synthesis and pharmacological activity as potent antinociceptive agents.
Topics: Adenosine; Analgesia; Analgesics; Animals; Indoles; Methylation; Mice; Molecular Structure; Nitrogen; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theophylline | 1994 |
The role of endogenous adenosine in a poststimulation increase in the acetylcholine content of a sympathetic ganglion.
Topics: Acetylcholine; Adenosine; Animals; Benzodiazepinones; Biological Transport; Cats; Dipyridamole; Electric Stimulation; Female; Male; Purinergic P1 Receptor Antagonists; Superior Cervical Ganglion; Theophylline | 1994 |
Modulation of striatal adenosine A1 and A2 receptors induces rotational behaviour in response to dopaminergic stimulation in intact rats.
Topics: Adenosine; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dopamine; Injections, Intraperitoneal; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1994 |
Functional evidence for retinal adenosine receptors.
Topics: Adenosine; Animals; Cattle; Dopamine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Receptors, Purinergic P1; Retina; Retinal Vessels; Swine; Theophylline; Vasodilation | 1994 |
Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia.
Topics: Animals; Animals, Newborn; Brain; Cerebral Cortex; Down-Regulation; Female; Guanosine Triphosphate; Hippocampus; Hypoxia; Ischemic Attack, Transient; Male; Neurons; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Tritium | 1994 |
Dipyridamole increases oxygen-glucose deprivation-induced injury in cortical cell culture.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dipyridamole; Glucose; Glutamates; Hypoxia, Brain; Kainic Acid; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Theophylline | 1994 |
Adenosine A1 receptor inhibition of glutamate exocytosis and protein kinase C-mediated decoupling.
Topics: 4-Aminopyridine; Adenosine; Animals; Cerebral Cortex; Enzyme Activation; Exocytosis; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Potassium Chloride; Protein Kinase C; Receptors, Purinergic; Synaptosomes; Theophylline | 1993 |
Adenosine A1 receptor-mediated inhibition of evoked glutamate release is coupled to calcium influx decrease in goldfish brain synaptosomes.
Topics: Adenosine; Amino Acids; Animals; Brain; Calcium; Calcium Channel Blockers; Fura-2; Glutamates; Glutamic Acid; Goldfish; Kinetics; omega-Conotoxins; Peptides; Phenylisopropyladenosine; Potassium; Receptors, Purinergic; Synaptosomes; Theophylline | 1993 |
High-performance liquid chromatography of the adenosine A1 agonist N6-cyclopentyladenosine and the A1 antagonist 8-cyclopentyltheophylline and its application in a pharmacokinetic study in rats.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Ligands; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1993 |
Endogenous adenosine does not activate ATP-sensitive potassium channels in the hypoxic guinea pig ventricle in vivo.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Cardiac Pacing, Artificial; Cell Hypoxia; Glyburide; Guanidines; Guinea Pigs; Heart Conduction System; Myocardium; Pinacidil; Potassium Channels; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Stereoisomerism; Theophylline | 1994 |
Involvement of adenosine in postictal events in rats given electroshock.
Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Electroshock; Female; Hindlimb; Male; Rats; Rats, Wistar; Seizures; Theophylline; Valproic Acid | 1994 |
Synergistic effects of angiotensin and adenosine in the renal microvasculature.
Topics: Adenosine; Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Drug Synergism; In Vitro Techniques; Isoquinolines; Kidney; Male; Microcirculation; Muscle, Smooth, Vascular; Purinergic P1 Receptor Antagonists; Quinapril; Rabbits; Rats; Rats, Sprague-Dawley; Renal Circulation; Saralasin; Tetrahydroisoquinolines; Theophylline; Vasoconstriction | 1994 |
Possible functional role of diadenosine polyphosphates: negative feedback for excitation in hippocampus.
Topics: Animals; Dinucleoside Phosphates; Feedback; Hippocampus; In Vitro Techniques; Membrane Potentials; Rats; Rats, Wistar; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline | 1994 |
Retinoblastoma protein is rapidly dephosphorylated by elevated cyclic adenosine monophosphate levels in human B-lymphoid cells.
Topics: B-Lymphocytes; Cell Cycle; Cell Division; Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Humans; Mitotic Index; Phosphoproteins; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinoblastoma Protein; Theophylline; Thymidine; Tumor Cells, Cultured | 1994 |
Immunoprecipitation of A1 adenosine receptor-GTP-binding protein complexes in ciliary epithelial cells.
Topics: Animals; Cattle; Cell Line; Cell Membrane; Cell Transformation, Viral; Cells, Cultured; Ciliary Body; GTP-Binding Proteins; Humans; Immunoglobulin G; Pigment Epithelium of Eye; Precipitin Tests; Radioligand Assay; Receptors, Purinergic P1; Simian virus 40; Theophylline | 1994 |
Mediation of the neuroprotective action of R-phenylisopropyl-adenosine through a centrally located adenosine A1 receptor.
Topics: Animals; Clonazepam; Hippocampus; Isoquinolines; Kainic Acid; Male; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Purinergic P1; Theophylline | 1993 |
Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Spatial Behavior; Theophylline | 1993 |
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Humans; Kinetics; Mutagenesis, Site-Directed; Point Mutation; Radioligand Assay; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Theophylline; Threonine; Tritium | 1994 |
Adenosine, a "retaliatory" metabolite, promotes anoxia tolerance in turtle brain.
Topics: Adenosine; Animals; Brain; Cerebellum; Hypoxia; In Vitro Techniques; Purinergic Antagonists; Theophylline; Turtles; Xanthines | 1993 |
Attenuation of potassium cyanide-mediated neuronal cell death by adenosine.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Neurons; Osmolar Concentration; Potassium Cyanide; Purinergic Antagonists; Theobromine; Theophylline | 1993 |
Differential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neurons.
Topics: Adenosine; Animals; Calcium Channels; Cyclic AMP; Electric Conductivity; Electrophysiology; Guinea Pigs; Hippocampus; Neurons; omega-Conotoxins; Peptides, Cyclic; Protein Kinase Inhibitors; Protein Kinases; Receptors, Purinergic; Theophylline | 1993 |
The effects of the adenosine reuptake inhibitor soluflazine on synaptic potentials and population hypoxic depolarizations in area CA1 of rat hippocampus in vitro.
Topics: Adenosine; Animals; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Piperazines; Rats; Rats, Inbred F344; Synapses; Synaptic Transmission; Theophylline | 1993 |
Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Baclofen; Electric Stimulation; Electrophysiology; Evoked Potentials; Hippocampus; Male; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic; Synapses; Theophylline | 1993 |
Role of adenosine in heterosynaptic, posttetanic depression in area CA1 of hippocampus.
Topics: Adenosine; Animals; Dendrites; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neurons, Afferent; Purinergic Antagonists; Rats; Synapses; Synaptic Transmission; Theophylline; Xanthines | 1993 |
Effects of caffeine and PD 116,600 on the differential-reinforcement-of-low rate 72-S (DRL 72-S) schedule of reinforcement.
Topics: Animals; Antidepressive Agents; Caffeine; Conditioning, Operant; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Theophylline | 1993 |
Endogenous adenosine delays the onset of hypoxic depolarization in the rat hippocampus in vitro via an action at A1 receptors.
Topics: Adenosine; Animals; Evoked Potentials; Gerbillinae; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Purinergic Antagonists; Rats; Receptors, Purinergic; Theophylline | 1993 |
Brain tissue hydrolysate acts on presynaptic adenosine receptors in the rat hippocampus.
Topics: Adenosine; Amino Acids; Animals; Hippocampus; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Time Factors | 1995 |
Latent N-methyl-D-aspartate receptors in the recurrent excitatory pathway between hippocampal CA1 pyramidal neurons: Ca(2+)-dependent activation by blocking A1 adenosine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Dizocilpine Maleate; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Models, Neurological; N-Methylaspartate; Picrotoxin; Potassium Chloride; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline; Time Factors | 1995 |
Purine suppression of proliferation of Sertoli-like TM4 cells in culture.
Topics: Adenosine; Animals; Caffeine; Cell Division; Cells, Cultured; Male; Mice; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1; Sertoli Cells; Theobromine; Theophylline | 1995 |
A novel irreversible antagonist of the A1-adenosine receptor.
Topics: Adenosine; Animals; Carbachol; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylyl Imidodiphosphate; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Kinetics; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Theophylline; Xanthines | 1996 |
Interstitial adenosine and function in rat heart in vivo: effects of adrenaline and 8-cyclopentyl-1,3-dimethylxanthine.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Epinephrine; Extracellular Space; Heart Ventricles; In Vitro Techniques; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Ventricular Function, Left | 1996 |
Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2a receptors in vivo.
Topics: 2-Chloroadenosine; Animals; Caffeine; Hemodynamics; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1996 |
Upregulated renal adenosine A1 receptors augment PKC and glucose transport but inhibit proliferation.
Topics: Adenosine Deaminase; Animals; Biological Transport; Caffeine; Cell Division; Cell Line; Glucose; Kidney; LLC-PK1 Cells; Phenylisopropyladenosine; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Swine; Theophylline; Up-Regulation | 1996 |
Adenosine A1 receptor blockade selectively potentiates the motor effects induced by dopamine D1 receptor stimulation in rodents.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; Motor Neurons; Oxidopamine; Purinergic P1 Receptor Antagonists; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Sympatholytics; Theophylline | 1996 |
The contribution of adenosine to paired-pulse inhibition in the normal and disinhibited hippocampal slice.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Central Nervous System Stimulants; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline | 1996 |
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Catecholamines; Corpus Striatum; Hippocampus; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Xanthines | 1997 |
Selective activation of cAMP-dependent protein kinase type I inhibits rat natural killer cell cytotoxicity.
Topics: Animals; Calcium; Carrier Proteins; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cytotoxicity, Immunologic; Enzyme Activation; Interleukin-2; Intracellular Signaling Peptides and Proteins; Ionomycin; Isoenzymes; Killer Cells, Natural; Lymphocytes; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Theophylline | 1997 |
Functional evidence for multiple purinoceptor subtypes in the rat medial vestibular nucleus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Evoked Potentials; In Vitro Techniques; Male; Neurons; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Theophylline; Thionucleotides; Time Factors; Vestibular Nuclei | 1997 |
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines | 1997 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Regulation of quantal transmitter secretion by ATP and protein kinases at developing neuromuscular synapses.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine Triphosphate; Animals; Cells, Cultured; Coculture Techniques; Embryo, Nonmammalian; Enzyme Inhibitors; Evoked Potentials; Kinetics; Muscle, Skeletal; Neuromuscular Junction; Neurons; Protein Kinases; Quantum Theory; Suramin; Synapses; Synaptic Transmission; Theophylline; Triazines; Xenopus laevis | 1997 |
Endogenous adenosine mediates the presynaptic inhibition induced by aglycemia at corticostriatal synapses.
Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Evoked Potentials; Glipizide; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Membrane Potentials; Neurons; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synapses; Theophylline; Tolbutamide; Xanthines | 1997 |
A role for adenosine A2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adenosine; Animals; Hippocampus; Long-Term Potentiation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1997 |
Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1997 |
Metabotropic glutamate receptor mediated long-term depression in developing hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Depression, Chemical; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neuroprotective Agents; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Theophylline | 1997 |
Adenosine stimulates nitric oxide synthesis in rat cardiac myocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Dactinomycin; Enzyme Inhibitors; Heart; Humans; Interleukin-1; Isoproterenol; Myocardium; Naphthalenes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Stereoisomerism; Theophylline; Xanthines | 1997 |
Adenosine depresses transmitter release but is not the basis for 'tetanic fade' at the neuromuscular junction of the rat.
Topics: Adenosine; Animals; Diaphragm; Electric Stimulation; Feedback; Female; In Vitro Techniques; Motor Endplate; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Theophylline; Xanthines | 1997 |
8-cyclopentyltheophylline, an adenosine A1 receptor antagonist, inhibits the reversal of long-term potentiation in hippocampal CA1 neurons.
Topics: Animals; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Neurons; Purinergic P1 Receptor Antagonists; Synaptic Transmission; Theophylline | 1997 |
Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine.
Topics: Animals; Behavior, Animal; Body Temperature; Edema; Histamine Release; Injections, Subcutaneous; Male; Pain; Plethysmography; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline | 1997 |
Influence of adenosine, dipyridamole, adenosine antagonists and antiepileptic drugs on EEG after discharge following cortical stimulation.
Topics: Adenosine; Aminophylline; Animals; Anticonvulsants; Cerebral Cortex; Dipyridamole; Electric Stimulation; Electroencephalography; Female; Male; Rats; Rats, Wistar; Seizures; Theophylline | 1997 |
Characterization of adenosine receptors mediating spinal sensory transmission related to nociceptive information in the rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Dose-Response Relationship, Drug; Female; Male; Pain; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex, Monosynaptic; Spinal Cord; Theophylline | 1997 |
A possible mechanism for the aglycemia-induced depression of glutamatergic excitation in the striatum.
Topics: Adenosine Triphosphate; Animals; Corpus Striatum; Electric Conductivity; Electrophysiology; Glucose; Glutamic Acid; Hypoglycemia; Microelectrodes; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Xanthines | 1997 |
Non-selective effects of adenosine A1 receptor ligands on energy metabolism and macromolecular biosynthesis in cultured central neurons.
Topics: Adenosine; Adenylyl Cyclases; Animals; Biological Transport; Cell Survival; Cells, Cultured; Cyclic AMP; Deoxyglucose; Embryo, Mammalian; Energy Metabolism; Female; Kinetics; Leucine; Ligands; Neurons; Prosencephalon; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA; Theophylline; Uridine | 1998 |
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline | 1998 |
Late developmental changes in the ability of adenosine A1 receptors to regulate synaptic transmission in the hippocampus.
Topics: Aging; Animals; Calcium; Colforsin; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theophylline | 1998 |
ATP and glutamate are released from separate neurones in the rat medial habenula nucleus: frequency dependence and adenosine-mediated inhibition of release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Aniline Compounds; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Habenula; Male; Neurons; Nucleotidases; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, Purinergic P1; Suramin; Synaptic Transmission; Synaptic Vesicles; Theophylline | 1998 |
Mitogenic action of adenosine on osteoblast-like cells, MC3T3-E1.
Topics: Adenosine; Animals; Becaplermin; Calcium; Cell Division; Cell Line; Dipyridamole; DNA; Humans; Kinetics; Mice; Osteoblasts; Pertussis Toxin; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Purinergic P1 Receptor Antagonists; Theophylline; Thymidine; Virulence Factors, Bordetella | 1998 |
Effects of adenosine on cholinergic transmission in mammalian vesical parasympathetic ganglia.
Topics: Adenosine; Animals; Cats; Excitatory Postsynaptic Potentials; Female; Ganglia, Parasympathetic; Hexamethonium; Hypogastric Plexus; In Vitro Techniques; Male; Nicotinic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Synaptic Transmission; Theophylline | 1997 |
Adenosine acts by A1 receptors to stimulate release of prolactin from anterior-pituitaries in vitro.
Topics: Adenosine; Animals; Follicle Stimulating Hormone; In Vitro Techniques; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Prolactin; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline | 1998 |
CPT (8-cyclopentyl theophylline) corrects CFTR antibody inhibited mucin secretion.
Topics: Adrenergic beta-Agonists; Animals; Antibodies; Cells, Cultured; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Isoproterenol; Mucins; Purinergic P1 Receptor Antagonists; Rats; Submandibular Gland; Theobromine; Theophylline | 1998 |
Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation.
Topics: Adenosine; Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hindlimb; Hyperesthesia; Male; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Theophylline | 1998 |
Multiple second-messenger system modulation of voltage-activated calcium currents in teleost retinal horizontal cells.
Topics: Animals; Bass; Calcium Channels; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Dopamine; Enzyme Activation; GTP-Binding Proteins; Membrane Potentials; Models, Biological; Neurons; Protein Kinase C; Retina; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Theophylline | 1998 |
Acute defense mechanisms against hemorrhage from mechanical gill injury in rainbow trout.
Topics: Animals; Arteries; Atropine; Cholinergic Antagonists; Gills; Hematocrit; Hemorrhage; Hemostatics; Indomethacin; Methysergide; Oncorhynchus mykiss; Purinergic P1 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin; Theophylline; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Enhancement of rapid eye movement sleep in the rat by cholinergic and adenosinergic agonists infused into the pontine reticular formation.
Topics: Adenosine; Animals; Atropine; Brain Mapping; Carbachol; Infusions, Parenteral; Male; Microinjections; Muscarinic Antagonists; Pons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Reticular Formation; Sleep; Sleep, REM; Theophylline; Time Factors; Wakefulness | 1998 |
Adenosine A1 and A2A receptor antagonists stimulate motor activity: evidence for an increased effectiveness in aged rats.
Topics: Aging; Animals; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Theophylline; Triazoles | 1998 |
Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures.
Topics: Adenosine; Adenosine Kinase; Animals; Cell Hypoxia; Cells, Cultured; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glucose; Neocortex; Neuroglia; Neurons; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyridamole; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Thioinosine; Vasodilator Agents; Xanthines | 1998 |
Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
Topics: Adenosine; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; CHO Cells; Cricetinae; Entropy; Humans; Kinetics; Point Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Theophylline; Thermodynamics; Threonine; Transfection; Xanthines | 1998 |
Actions of adenosine A1 and A2 receptor antagonists on CFTR antibody-inhibited beta-adrenergic mucin secretion response.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies; Chromatography, Gel; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electrophoresis, Cellulose Acetate; Mucins; Phosphorylation; Precipitin Tests; Purinergic P1 Receptor Antagonists; Rats; Receptors, Adrenergic, beta; Submandibular Gland; Theobromine; Theophylline | 1998 |
Pharmacological interactions between magnesium ion and adenosine on monoaminergic system in the central nervous system.
Topics: Adenosine; Animals; Biogenic Monoamines; Caffeine; Carbamazepine; Central Nervous System; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Magnesium; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline; Visual Cortex | 1998 |
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents | 1999 |
Adenosine inhibits L-type Ca2+ current and catecholamine release in the rabbit carotid body chemoreceptor cells.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carotid Body; Catecholamines; Chemoreceptor Cells; Dose-Response Relationship, Drug; Electrophysiology; Hypoxia; Ion Channel Gating; Membrane Potentials; Neuroprotective Agents; omega-Conotoxin GVIA; Peptides; Potassium; Rabbits; Sodium; Tetrodotoxin; Theophylline; Tritium; Xanthines | 1999 |
Lack of an effect of age on beta-adrenoceptor-mediated lipolysis in isolated human adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Biopsy; Buttocks; Cell Membrane; Cells, Cultured; Glycerol; Humans; Iodine Radioisotopes; Iodocyanopindolol; Isoproterenol; Lipolysis; Middle Aged; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Radiopharmaceuticals; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sodium, Dietary; Theophylline | 1999 |
A novel influence of adenosine on ongoing activity in rat rostral ventrolateral medulla.
Topics: Adenosine; Animals; Antihypertensive Agents; Bicuculline; Electric Stimulation; GABA Antagonists; Hypothalamus; Male; Medulla Oblongata; Neurons; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1999 |
Interaction between purinoceptor subtypes on hippocampal serotonergic transmission using in vivo microdialysis.
Topics: Adenosine Triphosphate; Animals; Hippocampus; Male; Microdialysis; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Serotonin; Theobromine; Theophylline; Thionucleotides | 1999 |
Effects of adenosinergic agents on the vascular resistance and on the optic nerve response in the perfused cat eye.
Topics: Adenosine; Animals; Cats; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Female; Optic Nerve; Perfusion; Phenethylamines; Photic Stimulation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retina; Theobromine; Theophylline; Vascular Resistance | 1999 |
Caffeine, acting on adenosine A(1) receptors, prevents the extinction of cocaine-seeking behavior in mice.
Topics: Animals; Behavior, Animal; Caffeine; Cocaine; Extinction, Psychological; Male; Mice; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Reward; Substance Abuse, Intravenous; Theophylline; Triazoles; Xanthines | 1999 |
The effects of adenosine ligands R-PIA and CPT on ethanol withdrawal.
Topics: Adenosine; Alcohol Drinking; Animals; Anti-Anxiety Agents; Central Nervous System Depressants; Ethanol; Male; Maze Learning; Purinergic P1 Receptor Agonists; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome; Theophylline | 1999 |
The adenosine A(1)-receptor antagonist 8-CPT reverses ethanol-induced inhibition of fetal breathing movements.
Topics: Animals; Blood Glucose; Blood Pressure; Electrocardiography; Ethanol; Eye Movements; Female; Fetal Blood; Fetal Movement; Fetus; Gases; Heart Rate, Fetal; Hemoglobins; Hydrogen-Ion Concentration; Lactic Acid; Pregnancy; Purinergic P1 Receptor Antagonists; Respiration; Sheep; Theophylline | 1999 |
An adenosine A3 receptor-selective agonist does not modulate calcium-activated potassium currents in hippocampal CA1 pyramidal neurons.
Topics: Adenosine; Animals; Calcium; Hippocampus; In Vitro Techniques; Male; Potassium Channels; Purinergic P1 Receptor Agonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Endogenous adenosine protects CA1 neurons from kainic acid-induced neuronal cell loss in the rat hippocampus.
Topics: Adenosine; Animals; Apoptosis; Disease Models, Animal; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Histocompatibility Antigens Class II; Injections, Intraventricular; Kainic Acid; Macrophage-1 Antigen; Male; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Phosphorylation; Proto-Oncogene Proteins c-jun; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1999 |
Effects of adenosine receptors on the synaptic and EPSP-spike components of long-term potentiation and depotentiation in the guinea-pig hippocampus.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Excitatory Postsynaptic Potentials; Guinea Pigs; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Organ Culture Techniques; Pyrazines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Theophylline | 1999 |
Adenosine receptor expression and modulation of Ca(2+) channels in rat striatal cholinergic interneurons.
Topics: Adenosine; Animals; Calcium Channels, N-Type; Choline O-Acetyltransferase; Corpus Striatum; Ethylmaleimide; GTP-Binding Proteins; Guanosine Diphosphate; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Rats; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theophylline; Thionucleotides | 2000 |
Endogenous adenosine regulates the effects of low-frequency stimulation on the induction of long-term potentiation in CA1 neurons of guinea pig hippocampal slices.
Topics: Adenosine; Afferent Pathways; Animals; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Pyrazines; Receptors, Purinergic P1; Theophylline | 2000 |
Histamine H(2) receptor activated chloride conductance in myenteric neurons from guinea pig small intestine.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Calcium Channel Blockers; Chlorides; Cyclic AMP; Cyclooxygenase Inhibitors; Electric Conductivity; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guinea Pigs; Histamine; Intestine, Small; Membrane Potentials; Myenteric Plexus; Neurons; Niflumic Acid; omega-Conotoxins; Paracrine Communication; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Receptors, Histamine H2; Stress, Psychological; Theophylline; Thionucleotides | 2000 |
Effects of A1 and A2 adenosine receptor antagonists on the induction and reversal of long-term potentiation in guinea pig hippocampal slices of CA1 neurons.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Dendrites; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Guinea Pigs; Hippocampus; Long-Term Potentiation; Neuronal Plasticity; Organ Culture Techniques; Pyramidal Cells; Pyrazines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Theophylline | 2000 |
Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline | 2000 |
N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats.
Topics: Adenosine; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Kindling, Neurologic; Male; Rats; Rats, Wistar; Theophylline; Valproic Acid | 2000 |
Properties of CFTR activated by the xanthine derivative X-33 in human airway Calu-3 cells.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Caffeine; Calcium Channel Blockers; Chlorides; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Iodides; Iodine Radioisotopes; Membrane Potentials; Membrane Proteins; ortho-Aminobenzoates; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Respiratory Mucosa; Theophylline; Xanthines | 2000 |
Mediation of the cardiovascular response to spinal gamma-aminobutyric acid(B) receptor stimulation by adenosine A(1) receptors in anesthetized rats.
Topics: Adenosine; Amino Acids, Neutral; Animals; Baclofen; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Spinal Cord; Sympathetic Nervous System; Theobromine; Theophylline | 2000 |
A novel transverse push-pull microprobe: in vitro characterization and in vivo demonstration of the enzymatic production of adenosine in the spinal cord dorsal horn.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Capsaicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Male; Microdialysis; Nitrophenols; Physical Stimulation; Posterior Horn Cells; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Spinal Cord; Theophylline | 2001 |
Distinct modulation of evoked and spontaneous EPSCs by purinoceptors in the nucleus tractus solitarii of the rat.
Topics: Adenosine Triphosphate; Animals; Brain Stem; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Male; Neurons; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic; Solitary Nucleus; Theophylline; Uridine Triphosphate; Xanthines | 2001 |
Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo.
Topics: Acid-Base Equilibrium; Adenosine; Animals; Blood Pressure; Caffeine; Carotid Artery, Common; Constriction; Excitatory Postsynaptic Potentials; Heart Rate; Hippocampus; Hypoxia-Ischemia, Brain; Male; Oxygen; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline | 2001 |
The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (Salmo trutta) optic tectum is inhibited by adenosine A1 receptors: effects of enucleation on A1 receptor density and cholinergic markers.
Topics: Acetylcholine; Acetylcholinesterase; Adenosine; Afferent Pathways; Animals; Calcium; Calcium Channel Blockers; Choline O-Acetyltransferase; Kinetics; Membrane Potentials; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Superior Colliculi; Synaptosomes; Theophylline; Tritium; Trout | 2001 |
Effect of lactate on the synaptic potential, energy metabolism, calcium homeostasis and extracellular glutamate concentration in the dentate gyrus of the hippocampus from guinea-pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycolysis; Guinea Pigs; Homeostasis; Intracellular Fluid; Lactic Acid; Neurons; Nimodipine; Organ Culture Techniques; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Theophylline | 2001 |
Sleep-wake and eeg effects following adenosine a1 agonism and antagonism: similarities and interactions with sleep-wake and eeg effects following a serotonin reuptake inhibitor in rats.
Topics: Analysis of Variance; Animals; Drug Synergism; Electroencephalography; Male; Purinergic P1 Receptor Antagonists; Rats; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Stages; Sleep, REM; Theophylline; Wakefulness; Zimeldine | 1998 |
Mechanisms underlying the depression of evoked fast EPSCs following in vitro ischemia in rat hippocampal CA1 neurons.
Topics: Animals; Brain Ischemia; Calcium; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Neurons; Presynaptic Terminals; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Tetrodotoxin; Theophylline | 2001 |
Catalepsy and hypolocomotion induced by a nitric oxide donor: attenuation by theophylline.
Topics: Animals; Behavior, Animal; Catalepsy; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Nitric Oxide Donors; Nitroprusside; Purinergic P1 Receptor Antagonists; Theophylline; Time Factors; Vasodilator Agents | 2001 |
The CFTR-mediated protein secretion defect: pharmacological correction.
Topics: Adrenergic beta-Agonists; Animals; Cell Line; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Humans; Isoproterenol; Lactoferrin; Mucins; Nasal Mucosa; Rats; Submandibular Gland; Theophylline; Thionucleotides | 2001 |
Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.
Topics: Adenosine; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium; Cells, Cultured; Dermis; DNA Primers; Endothelial Growth Factors; Gene Expression; Hair; Humans; Hypertrichosis; Lymphokines; Minoxidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Antagonists; Receptors, Drug; Receptors, Purinergic P1; Sulfonylurea Receptors; Theobromine; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2001 |
Different activation mechanisms of cystic fibrosis transmembrane conductance regulator expressed in Xenopus laevis oocytes.
Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Microinjections; Oocytes; Theophylline; Xenopus laevis | 2001 |
Adenosine inhibition via A(1) receptor of N-type Ca(2+) current and peptide release from isolated neurohypophysial terminals of the rat.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine Vasopressin; Barium; Calcium Channels, N-Type; In Vitro Techniques; Kinetics; Membrane Potentials; Nerve Endings; Oxytocin; Patch-Clamp Techniques; Pituitary Gland, Posterior; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline | 2002 |
Relationship between bicarbonate and cyclic nucleotide in the promoting effects on head-to-head agglutination in boar spermatozoa.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Male; Papaverine; Purinergic P1 Receptor Antagonists; Sodium Bicarbonate; Sperm Agglutination; Sperm Head; Swine; Theophylline | 2002 |
Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo.
Topics: Adenosine; Animals; Cell Death; Cerebrovascular Circulation; Hippocampus; Hypoxia-Ischemia, Brain; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Organ Culture Techniques; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Subcellular Fractions; Synaptic Transmission; Theophylline; Up-Regulation | 2002 |
Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens.
Topics: Animals; Behavior, Animal; Caffeine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Injections, Intraperitoneal; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Theophylline; Triazoles; Wakefulness | 2002 |
Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells.
Topics: Adenosine; Animals; Cattle; Cell Line, Transformed; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Time Factors; Trabecular Meshwork | 2002 |
Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus.
Topics: Adenosine; Animals; Cardiovascular Physiological Phenomena; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline | 2002 |
Saturation of neuroprotective effects of adenosine in cortical culture.
Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular Space; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2002 |
Regulation by Rab3A of an endogenous modulator of neurotransmitter release at mouse motor nerve endings.
Topics: Acetylcholine; Adenosine; Animals; Diaphragm; Electric Stimulation; Electrophysiology; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Patch-Clamp Techniques; Phenotype; Phrenic Nerve; Purinergic P1 Receptor Antagonists; rab3A GTP-Binding Protein; Theophylline | 2002 |
The influence of adenosine A3 receptor agonist: IB-MECA, on scopolamine- and MK-801-induced memory impairment.
Topics: Adenosine; Animals; Avoidance Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Maze Learning; Memory; Memory Disorders; Mice; Motor Activity; Muscarinic Antagonists; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Scopolamine; Theophylline | 2003 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity.
Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Caffeine; Cells, Cultured; Central Nervous System Diseases; Cerebellum; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar; Receptor, Adenosine A2A; Theophylline; Triazines; Triazoles | 2003 |
Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adolescent; Adult; CD4-Positive T-Lymphocytes; Cells, Cultured; Child; Child, Preschool; Common Variable Immunodeficiency; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Female; Humans; Interleukin-10; Leukocyte Common Antigens; Lymphocyte Activation; Male; Middle Aged; Protein Subunits; T-Lymphocyte Subsets; Theophylline; Thionucleotides; Up-Regulation | 2003 |
Systemic hypoxia and the depression of synaptic transmission in rat hippocampus after carotid artery occlusion.
Topics: Adenosine; Animals; Carotid Arteries; Cerebrovascular Circulation; Electrophysiology; Excitatory Postsynaptic Potentials; Functional Laterality; Hippocampus; Hypoxia; In Vitro Techniques; Injections, Intraventricular; Laser-Doppler Flowmetry; Male; Oxygen; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Theophylline | 2003 |
The effect of acute hypoxemia and hypotension on adenosine-mediated depression of evoked hippocampal synaptic transmission.
Topics: Acute Disease; Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Carotid Artery, Common; Cerebrovascular Circulation; Excitatory Postsynaptic Potentials; Hippocampus; Hypotension; Hypoxia; Male; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
Topics: Adenosine; Animals; Auditory Pathways; Baclofen; Blotting, Western; Brain Stem; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Neural Inhibition; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Synaptophysin; Tetrodotoxin; Theophylline | 2003 |
Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Methamphetamine; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Xanthines | 2003 |
Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Time; Xanthines | 2004 |
Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner.
Topics: Adenosine; Animals; Animals, Newborn; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indoles; Maleimides; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Seizures; Theophylline; Time Factors; Triazines; Triazoles | 2004 |
The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System; Synaptic Transmission; Theobromine; Theophylline; Triazines; Triazoles | 2004 |
Glutamate-evoked release of adenosine and regulation of peripheral nociception.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrates; Conditioning, Psychological; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Gliosis; Glutamic Acid; Male; Microglia; Neural Inhibition; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Theophylline | 2004 |
Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion.
Topics: Adenosine; Animals; Drug Administration Routes; Extracellular Fluid; Infusions, Parenteral; Kynurenic Acid; Male; Microdialysis; Neostriatum; Neurons; Phenethylamines; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Theophylline; Wakefulness | 2004 |
Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro.
Topics: Adenosine A1 Receptor Antagonists; Animals; Brain Ischemia; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Receptor, Adenosine A1; Theophylline | 2004 |
Pharmacological preconditioning with resveratrol: role of CREB-dependent Bcl-2 signaling via adenosine A3 receptor activation.
Topics: Adenosine A3 Receptor Antagonists; Animals; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Heart; Male; Myocardial Infarction; Myocytes, Cardiac; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Resveratrol; Signal Transduction; Stilbenes; Theophylline | 2005 |
Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials, Motor; Female; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Reflex, Monosynaptic; Spinal Cord; Spinal Nerve Roots; Stress, Mechanical; Theophylline | 2004 |
Adenosine A(1)-receptor-mediated tonic inhibition of glutamate release at rat hippocampal CA3-CA1 synapses is primarily due to inhibition of N-type Ca(2+) channels.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; Rats; Rats, Wistar; Receptor, Adenosine A1; Synapses; Synaptic Transmission; Theophylline | 2004 |
Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Nucleus Accumbens; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Synaptic Transmission; Theophylline | 2004 |
Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.
Topics: 4-Aminopyridine; Adenosine; alpha-Synuclein; Analgesics; Anesthetics, Local; Animals; Blotting, Western; Drug Interactions; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Potassium Channel Blockers; Synaptic Transmission; Synucleins; Tetrodotoxin; Theophylline; Time Factors | 2004 |
Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum.
Topics: Acetylcholine; Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Animals; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Estriol; Excitatory Postsynaptic Potentials; GABA Antagonists; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Iontophoresis; Male; Mecamylamine; Myenteric Plexus; Naloxone; Narcotic Antagonists; Neural Inhibition; Neurons; Nicotinic Antagonists; Peptides; Picrotoxin; Piperazines; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Serotonin 5-HT1 Receptor Antagonists; Theophylline; Time Factors | 2005 |
Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
Stabilizing effects of extracellular ATP on synaptic efficacy and plasticity in hippocampal pyramidal neurons.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Caffeine; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Purinergic P2 Receptor Antagonists; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Time Factors | 2005 |
Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia.
Topics: Adenosine A1 Receptor Antagonists; Animals; Dependovirus; Electric Stimulation; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Hypoxia; In Situ Hybridization; In Vitro Techniques; Integrases; Mice; Mice, Knockout; Neural Inhibition; Presynaptic Terminals; Receptor, Adenosine A1; Recovery of Function; Synaptic Transmission; Theophylline; Time Factors | 2005 |
Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Cholecystokinin; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Receptor, Adenosine A1; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Theophylline | 2005 |
Phase-specific central regulatory systems of hibernation in Syrian hamsters.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Antibodies; Arousal; Basal Metabolism; Body Temperature; Body Temperature Regulation; Brain; Circadian Rhythm; Cricetinae; Female; Hibernation; Injections, Intraventricular; Male; Mesocricetus; Narcotic Antagonists; Opioid Peptides; Receptor, Adenosine A1; Receptors, Opioid, mu; Respiratory Physiological Phenomena; Theophylline; Thyrotropin-Releasing Hormone; Time Factors | 2005 |
Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Benzoxazines; Cholecystokinin; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naloxone; Naphthalenes; Narcotic Antagonists; Neurons; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rimonabant; Substance Withdrawal Syndrome; Theophylline | 2005 |
Effect of sleep deprivation on righting reflex in the rat is partially reversed by administration of adenosine A1 and A2 receptor antagonists.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Drug Combinations; Male; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Reflex; Sleep Deprivation; Theophylline; Triazines; Triazoles | 2005 |
Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.
Topics: 4-Aminopyridine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Cell Communication; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; In Vitro Techniques; Interneurons; Lysine; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Tetraethylammonium; Theophylline | 2005 |
Adenosine receptors co-operate with NMDA preconditioning to protect cerebellar granule cells against glutamate neurotoxicity.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; Cyclic AMP; Drug Antagonism; Excitatory Amino Acid Agonists; Glutamic Acid; Hydrolysis; N-Methylaspartate; Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles | 2005 |
Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.
Topics: Adenosine; Adenosine Deaminase; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Emodin; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Valine | 2005 |
Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anterior Eye Segment; Aqueous Humor; Cattle; Dipeptides; Dose-Response Relationship, Drug; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Protease Inhibitors; Receptor, Adenosine A1; Theophylline; Time Factors | 2005 |
Presynaptic effectors contributing to cAMP-induced synaptic potentiation in Drosophila.
Topics: Animals; Brefeldin A; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Drosophila; Guanine Nucleotide Exchange Factors; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Long-Term Potentiation; Neuromuscular Junction; Patch-Clamp Techniques; Potassium Channels; Protein Synthesis Inhibitors; Synaptic Transmission; Theophylline | 2006 |
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine.
Topics: 2-Aminopurine; Adenine; Adjuvants, Immunologic; Animals; Anti-HIV Agents; Caffeine; Cell Survival; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Dihydropyridines; Dose-Response Relationship, Drug; Female; Flavins; Humans; Interleukin-10; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Organophosphonates; Purinergic P1 Receptor Antagonists; Quinazolines; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death.
Topics: Adenosine; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Astrocytoma; Caspases; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Immunohistochemistry; Mitochondrial Membranes; Models, Biological; Multienzyme Complexes; Protein Serine-Threonine Kinases; Rats; Receptor, Adenosine A1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Theophylline; Thiazoles | 2006 |
Activity-dependent feedback modulation of spike patterning of supraoptic nucleus neurons by endogenous adenosine.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Feedback, Physiological; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Supraoptic Nucleus; Theophylline | 2006 |
Molecular mechanisms of adenosine-induced apoptosis in human HepG2 cells.
Topics: Adenosine; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dipyridamole; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Liver Neoplasms; Membrane Potentials; Mitochondria, Liver; Theophylline | 2006 |
Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bumetanide; Chlorides; Dose-Response Relationship, Drug; Electric Stimulation; Electrolytes; Gene Expression; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Vasoactive Intestinal Polypeptide, Type I; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors; Tetrodotoxin; Theophylline; Triazines; Triazoles; Vasoactive Intestinal Peptide | 2006 |
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Angiotensin II; Animals; Arterioles; Feedback; Female; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Purines; Receptor, Adenosine A1; Receptors, Adenosine A2; Theophylline; Triazines; Triazoles; Vasoconstriction; Vasodilation | 2006 |
Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Drug Administration Schedule; Functional Laterality; Guanosine 5'-O-(3-Thiotriphosphate); Physical Stimulation; Protein Binding; Rats; Receptor, Adenosine A1; Sensory Thresholds; Spinal Cord; Spinal Cord Diseases; Sulfur Isotopes; Theophylline | 2006 |
Stimulation of adenosine A1 and A2A receptors by AMP in the submucosal plexus of guinea pig small intestine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Boron Compounds; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Guinea Pigs; Ileum; Indoles; Male; Maleimides; Norepinephrine; Phenethylamines; Pyrrolidinones; Quinazolines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Signal Transduction; Submucous Plexus; Synaptic Transmission; Tetrodotoxin; Theophylline; Triazines; Triazoles | 2007 |
Forskolin and 8-cyclopentyltheophylline synergistically facilitate the neuronal activity in the CA2 area of rat hippocampus via cAMP and non-cAMP cascades.
Topics: Adenosine A1 Receptor Antagonists; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Synergism; Hippocampus; Long-Term Potentiation; Male; Neurons; Rats; Rats, Wistar; Theophylline | 2006 |
Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline | 2007 |
Changes in neuromodulatory effect of adenosine A1 receptors on piriform cortex field potentials in amygdala kindled rats.
Topics: Adenosine; Amygdala; Animals; Excitatory Postsynaptic Potentials; Kindling, Neurologic; Male; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Theophylline | 2007 |
Paired-pulse ratio of synaptically induced transporter currents at hippocampal CA1 synapses is not related to release probability.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Neurons; Probability; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synapses; Theophylline | 2007 |
Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.
Topics: 5'-Nucleotidase; Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glioma; Humans; Indomethacin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Theophylline; Time Factors; Triazoles; Xanthines | 2007 |
Anticonvulsant effect of A1 but not A2A adenosine receptors of piriform cortex in amygdala-kindled rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amygdala; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Kindling, Neurologic; Male; Microinjections; Models, Anatomic; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Triazines; Triazoles | 2007 |
Nitric oxide modulates the discharge rate of basal forebrain neurons.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Diagonal Band of Broca; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Extracellular Space; Male; Microdialysis; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Physical Stimulation; Preoptic Area; Prosencephalon; Rats; Rats, Wistar; Substantia Innominata; Theophylline; Touch Perception; Urethane | 2008 |
Correlation of intrinsic optical signal, cerebral blood flow, and evoked potentials during activation of rat somatosensory cortex.
Topics: Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Evoked Potentials, Somatosensory; Hindlimb; Male; Optics and Photonics; Pia Mater; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Theophylline; Vasodilator Agents | 2008 |
Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Biological Clocks; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Fourier Analysis; Hippocampus; Hypoxia; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Thioinosine; Time Factors; Triazines; Triazoles | 2009 |
Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus.
Topics: Adenosine; Adenosine Kinase; Animals; Animals, Newborn; Astrocytes; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Hippocampus; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Seizures; Synapses; Theophylline; Time Factors; Tubercidin | 2009 |
PKA-dependent and independent cAMP signaling in 3T3-L1 fibroblasts differentiation.
Topics: 1-Methyl-3-isobutylxanthine; 3T3-L1 Cells; Adipogenesis; Animals; Cell Differentiation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Fibroblasts; Insulin; Isoquinolines; Mice; Mitosis; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Theophylline | 2009 |
Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Biomarkers; Cerebral Cortex; Dose-Response Relationship, Drug; Gene Expression Regulation; Limbic System; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Theophylline; Ventral Tegmental Area | 2009 |
Roles of purines in synaptic modulation evoked by hypercapnia in isolated spinal cord of neonatal rat in vitro.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Animals, Newborn; Electrophysiology; Evoked Potentials; Extracellular Space; Female; Hypercapnia; In Vitro Techniques; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Reflex; Spinal Cord; Synaptic Transmission; Theophylline | 2009 |
The role of the basal forebrain adenosine receptors in sleep homeostasis.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Catheterization; Electrodes, Implanted; Electroencephalography; Homeostasis; Male; Prosencephalon; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sleep; Sleep Deprivation; Theobromine; Theophylline | 2009 |
Differential effects of adenosine antagonists in two models of parkinsonian tremor.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Synergism; Jaw; Male; Parkinsonian Disorders; Pimozide; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Tacrine; Theophylline; Tremor; Triazoles | 2009 |
Epac1-induced cellular proliferation in prostate cancer cells is mediated by B-Raf/ERK and mTOR signaling cascades.
Topics: Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; Humans; Intracellular Signaling Peptides and Proteins; Male; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins B-raf; Signal Transduction; Theophylline; TOR Serine-Threonine Kinases | 2009 |
Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines.
Topics: Animals; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Dendritic Spines; Depression; Dopamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Gene Expression Regulation; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Humans; Immunoprecipitation; Membrane Potentials; Neurons; Patch-Clamp Techniques; Point Mutation; rap1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; RNA, Small Interfering; Synapses; Synaptic Transmission; Theophylline; Transfection | 2009 |
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relationship, Drug; Enteric Nervous System; Gastrointestinal Motility; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Intestinal Secretions; Male; Mecamylamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neural Inhibition; Neurogenic Bowel; Neurokinin-1 Receptor Antagonists; Nicotinic Antagonists; Piperidines; Propane; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Histamine H2; Receptors, Neurokinin-1; Reflex; Theophylline; Xanthines | 2009 |
Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect.
Topics: Adrenergic beta-Agonists; Animals; Blotting, Western; Cell Communication; Cells, Cultured; Connexin 43; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gap Junctions; Guanine Nucleotide Exchange Factors; Ischemic Preconditioning, Myocardial; Isoproterenol; Myocytes, Cardiac; Organ Culture Techniques; Phosphorylation; Protein Kinase C-epsilon; Rats; Theophylline | 2010 |
Sleep fragmentation attenuates the hypercapnic (but not hypoxic) ventilatory responses via adenosine A1 receptors in awake rats.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Blood Gas Analysis; Hypercapnia; Locomotion; Male; Plethysmography; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Respiration; Sleep Deprivation; Theophylline; Time Factors; Wakefulness | 2011 |
Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.
Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Amino Acids; Animals; Baclofen; Barium; Bee Venoms; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cesium; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Potassium Channel Blockers; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Theophylline; Xanthenes | 2011 |
Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice.
Topics: Adenosine; Analysis of Variance; Animals; Astrocytes; Electrophysiology; Exocytosis; Female; Hippocampus; Male; Memory; Mice; Mice, Transgenic; Neuronal Plasticity; Receptor, Adenosine A1; Sleep Deprivation; SNARE Proteins; Synapses; Theophylline | 2011 |
Combined effects of THC and caffeine on working memory in rats.
Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Dronabinol; Drug Synergism; Male; Memory, Short-Term; Rats; Rats, Long-Evans; Receptor, Adenosine A1; Theophylline | 2012 |
Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A(1) receptors.
Topics: Adenosine; Animals; Arctic Regions; Body Temperature; Body Temperature Regulation; Brain; Hibernation; Injections, Intraventricular; Oxygen Consumption; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Sciuridae; Seasons; Telemetry; Theophylline; Xanthines | 2011 |
Inducing hibernation in the arctic ground squirrel.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Arctic Regions; Brain; Hibernation; Receptor, Adenosine A1; Sciuridae; Seasons; Theophylline | 2011 |
Presynaptic inhibition of GABAergic synaptic transmission by adenosine in mouse hypothalamic hypocretin neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Animals; Animals, Newborn; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agents; GABAergic Neurons; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neural Inhibition; Neuropeptides; Orexins; Patch-Clamp Techniques; Presynaptic Terminals; Purinergic Antagonists; Synaptic Transmission; Theobromine; Theophylline; Valine | 2012 |
Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine.
Topics: Adenosine; Animals; Astrocytes; Cerebral Cortex; Excitatory Postsynaptic Potentials; Extracellular Fluid; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptor, Adenosine A1; Sleep Deprivation; Synaptic Transmission; Theophylline; Vesicle-Associated Membrane Protein 2; Wakefulness | 2012 |
Evidence for constitutively-active adenosine receptors at mammalian motor nerve endings.
Topics: Acetylcholine; Adenosine A1 Receptor Antagonists; Adenosine Deaminase; Animals; Calcium; Dose-Response Relationship, Drug; Drug Inverse Agonism; Magnesium; Mice; Motor Neurons; Nerve Endings; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Xanthines | 2012 |
Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biophysics; Brain; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nerve Fibers; Neural Inhibition; Potassium Chloride; Quinoxalines; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 2012 |
Heterosynaptic long-term depression mediated by ATP released from astrocytes.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antigens; Astrocytes; Biophysics; Calcium; Calcium Signaling; Cells, Cultured; Channelrhodopsins; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Genetic Vectors; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Neurons; Optical Phenomena; Patch-Clamp Techniques; Proteoglycans; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Serine; Theophylline; Time Factors; Transfection | 2013 |
Cortical spreading depression-induced preconditioning in mouse neocortex is lamina specific.
Topics: Adenosine; Animals; Brain Waves; Calcium; Carbon Dioxide; Cell Hypoxia; Cortical Spreading Depression; Dipyridamole; Dose-Response Relationship, Drug; Glucose; Ischemic Preconditioning; Membrane Potentials; Mice; Neocortex; Neural Inhibition; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Theophylline | 2013 |
Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine.
Topics: Action Potentials; Adenosine; Alcohols; Animals; Brain Waves; Electroencephalography; Excitatory Postsynaptic Potentials; Extracellular Fluid; Hippocampus; Homeostasis; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Movement Disorders; Neurons; Purinergic P1 Receptor Antagonists; Sleep Deprivation; Sleep Stages; Theophylline; Thioinosine; Time Factors; Wakefulness | 2014 |
The role of alpha-2 adrenoceptors in the anticonvulsant effects of adenosine on pentylenetetrazole-induced seizure threshold in mice.
Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Anticonvulsants; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Pentylenetetrazole; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Seizures; Theophylline; Yohimbine | 2014 |
Adenosine signaling in reserpine-induced depression in rats.
Topics: Adenosine; Adrenergic Uptake Inhibitors; Animals; Brain; Caffeine; Depressive Disorder; Dose-Response Relationship, Drug; Flavins; Male; Neuropsychological Tests; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Random Allocation; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reserpine; Swimming; Theophylline | 2015 |
Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors.
Topics: Animals; Central Nervous System Depressants; Electroencephalography; Electromyography; Gene Expression; Genes, fos; Glucosides; Histamine; Injections, Intraperitoneal; Male; Mammillary Bodies; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoterpenes; Neurons; Paeonia; Patch-Clamp Techniques; Receptor, Adenosine A1; Sleep; Theophylline | 2016 |
Oral administration of Japanese sake yeast (Saccharomyces cerevisiae sake) promotes non-rapid eye movement sleep in mice via adenosine A
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Administration, Oral; Alcoholic Beverages; Animals; Electroencephalography; Electromyography; Eye Movements; Japan; Locomotion; Male; Mice; Mice, Inbred C57BL; Receptor, Adenosine A2A; Saccharomyces cerevisiae; Sleep; Sleep, REM; Theophylline; Time Factors; Triazines; Triazoles | 2016 |
The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex.
Topics: Animals; Antioxidants; Behavior, Animal; Cerebral Cortex; Dizocilpine Maleate; Drug Synergism; Immobility Response, Tonic; Lipid Peroxidation; Male; Mice; Motor Activity; Oxidation-Reduction; Theophylline | 2017 |
Adenosine Receptor-Mediated Developmental Loss of Spike Timing-Dependent Depression in the Hippocampus.
Topics: Action Potentials; Adenosine A1 Receptor Agonists; Animals; Animals, Newborn; Astrocytes; Bicuculline; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; Hippocampus; Immunohistochemistry; Long-Term Synaptic Depression; Mice; Microscopy, Electron; Neuronal Plasticity; Patch-Clamp Techniques; Presynaptic Terminals; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline | 2019 |