theophylline has been researched along with 4-aminopyridine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (26.92) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Luk'ianets, EA | 1 |
| Broadley, KJ; Rothaul, AL; Urquhart, RA | 1 |
| Peracchia, C | 1 |
| Garrino, MG; Henquin, JC; Hermans, M; Nenquin, M; Paolisso, G | 1 |
| Simpson, LL | 1 |
| Chaudhry, IA; Duncalf, D; Foldes, FF; Goldiner, PL; Nagashima, H; Somogyi, GT; Vizi, ES | 1 |
| Heinemann, U; Schubert, P | 1 |
| Alkadhi, KA; Brown, TR; Sabouni, MH | 1 |
| Gundersen, CB; Jenden, DJ | 1 |
| Osmanović, SS; Pan, WJ; Shefner, SA | 1 |
| Barrie, AP; Nicholls, DG | 1 |
| Broadley, KJ; Gardner, NM | 1 |
| Bardou, M; Dumas, J; Dumas, M; Goirand, F; Rochette, L | 1 |
| Küçukhüseyin, C; Oncel, H; Silan, C | 1 |
| Antończyk, A; Kochman, K; Magdalan, J; Przewłocki, M; Smolarek, M | 1 |
| Ceña, V; Fariñas, I; González-García, C; Martín, ED; Milán, M | 1 |
| Fujii, S; Hozumi, Y; Kaneko, K; Kato, H; Kudo, Y; Li, J; Miyakawa, H; Yamazaki, Y | 1 |
| Peikov, P; Tencheva, J; Tsvetkova, B | 1 |
| Leniger, T; Splettstösser, F; Thöne, J; Wiemann, M | 1 |
| Borbouse, L; Bratz, IN; Dick, GM; Dincer, UD; Knudson, JD; Payne, GA; Rogers, PA; Tune, JD | 1 |
| Andreasen, M; Hablitz, JJ; Nedergaard, S; Skov, J | 1 |
26 other study(ies) available for theophylline and 4-aminopyridine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
[The effect of intracellular calcium on an increase in the cAMP-mediated calcium current].
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Animals; Calcium; Calcium Channels; Creatinine; Cyclic AMP; Drug Combinations; Drug Interactions; Egtazic Acid; Helix, Snails; In Vitro Techniques; Membrane Potentials; Neurons; Serotonin; Theophylline; Trifluoperazine | 1991 |
86Rubidium efflux and negative inotropy induced by P1- and muscarinic-receptor agonists in guinea-pig left atria. Effects of potassium channel blockers.
Topics: 4-Aminopyridine; Adenosine; Amantadine; Animals; Carbachol; Drug Interactions; Guinea Pigs; Half-Life; Heart Atria; Male; Parasympathomimetics; Phenylisopropyladenosine; Potassium; Potassium Channels; Rubidium Radioisotopes; Theophylline | 1991 |
Effects of the anesthetics heptanol, halothane and isoflurane on gap junction conductance in crayfish septate axons: a calcium- and hydrogen-independent phenomenon potentiated by caffeine and theophylline, and inhibited by 4-aminopyridine.
Topics: 4-Aminopyridine; Alcohols; Anesthetics; Animals; Astacoidea; Axons; Caffeine; Calcium; Electric Conductivity; Halothane; Heptanol; Hydrogen-Ion Concentration; Intercellular Junctions; Isoflurane; Kinetics; Membrane Potentials; Theophylline | 1991 |
Pharmacological control of 86Rb efflux from mouse pancreatic islets.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Female; In Vitro Techniques; Insulin; Insulin Secretion; Ion Channels; Islets of Langerhans; Kinetics; Mice; Mice, Inbred Strains; Quinine; Radioisotopes; Rubidium; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
Use of pharmacologic antagonists to deduce commonalities of biologic activity among clostridial neurotoxins.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; Acetylcholine; Amifampridine; Aminopyridines; Ammonium Chloride; Animals; Botulinum Toxins; Calcium; Cholera Toxin; Colforsin; Female; Guanidine; Guanidines; In Vitro Techniques; Methylamines; Mice; Neuromuscular Junction; Neurotoxins; Tetanus Toxin; Theophylline | 1988 |
Modulation of stimulation-evoked release of newly formed acetylcholine from mouse hemidiaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine; Aminopyridines; Animals; Atropine; Calcium; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Mice; Neuromuscular Junction; Oxotremorine; Tetrodotoxin; Theophylline; Xylazine | 1987 |
Adenosine antagonists combined with 4-aminopyridine cause partial recovery of synaptic transmission in low Ca media.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Deaminase; Aminopyridines; Animals; Calcium; Electric Stimulation; Hippocampus; In Vitro Techniques; Nucleoside Deaminases; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1988 |
Inhibitory effect of adenosine on transmission in sympathetic ganglia.
Topics: 2-Chloroadenosine; 4-Aminopyridine; Action Potentials; Adenosine; Aminopyridines; Animals; Dipyridamole; Electric Stimulation; Female; Ganglia, Sympathetic; In Vitro Techniques; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1984 |
Studies of the effects of agents which alter calcium metabolism on acetylcholine turnover in the rat diaphragm preparation.
Topics: 4-Aminopyridine; Acetylcholine; Aminopyridines; Animals; Bungarotoxins; Calcimycin; Calcium; Diaphragm; Dinitrophenols; Guanidine; Guanidines; In Vitro Techniques; Lanthanum; Male; Ouabain; Rats; Tetraethylammonium Compounds; Theophylline | 1981 |
Characterization of the adenosine A1 receptor-activated potassium current in rat locus ceruleus neurons.
Topics: 4-Aminopyridine; Adenosine; Animals; Barium; Dose-Response Relationship, Drug; Glyburide; Locus Coeruleus; Male; Membrane Potentials; Neurons; Potassium Channels; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Theophylline | 1995 |
Adenosine A1 receptor inhibition of glutamate exocytosis and protein kinase C-mediated decoupling.
Topics: 4-Aminopyridine; Adenosine; Animals; Cerebral Cortex; Enzyme Activation; Exocytosis; Fura-2; Glutamates; Glutamic Acid; Guinea Pigs; Potassium Chloride; Protein Kinase C; Receptors, Purinergic; Synaptosomes; Theophylline | 1993 |
Resistance to antagonism of atrial P(1) purinoceptor responses in the presence of K(+) channel blockade.
Topics: 4-Aminopyridine; Adenosine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Heart Atria; Male; Myocardial Contraction; Potassium Channel Blockers; Propranolol; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Reserpine; Signal Transduction; Theophylline | 1999 |
Effects of phosphodiesterase inhibitors on hypoxic pulmonary vasoconstriction. Influence of K(+) channels and nitric oxide.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Potassium Channels; Purinones; Rats; Rats, Wistar; Rolipram; Theophylline; Vasoconstriction | 2001 |
On the mechanisms of post-rest adaptation in the isolated electrically driven left atria of rats.
Topics: 4-Aminopyridine; Adaptation, Physiological; Animals; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Electric Stimulation; Female; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Rest; Theophylline; Vasodilator Agents; Verapamil | 2002 |
[Severe felodipine and theophylline poisoning successfully treated by 4-aminopyridine: a case report].
Topics: 4-Aminopyridine; Felodipine; Humans; Hypotension; Intestinal Pseudo-Obstruction; Male; Middle Aged; Potassium Channel Blockers; Suicide, Attempted; Tachycardia; Theophylline; Vasodilator Agents | 2003 |
Stressor-related impairment of synaptic transmission in hippocampal slices from alpha-synuclein knockout mice.
Topics: 4-Aminopyridine; Adenosine; alpha-Synuclein; Analgesics; Anesthetics, Local; Animals; Blotting, Western; Drug Interactions; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Potassium Channel Blockers; Synaptic Transmission; Synucleins; Tetrodotoxin; Theophylline; Time Factors | 2004 |
Direct evidence for mutual interactions between perineuronal astrocytes and interneurons in the CA1 region of the rat hippocampus.
Topics: 4-Aminopyridine; Adenosine A1 Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Cell Communication; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; In Vitro Techniques; Interneurons; Lysine; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Quinoxalines; Rats; Tetraethylammonium; Theophylline | 2005 |
Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether.
Topics: 4-Aminopyridine; Dicyclohexylcarbodiimide; Esterification; Ethylene Glycols; Kinetics; Theophylline; Urea | 2006 |
Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Electrophysiology; Epilepsy; Female; Guinea Pigs; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Isoxazoles; Membrane Potentials; Microelectrodes; Neurons; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Theophylline; Zonisamide | 2008 |
Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation.
Topics: 4-Aminopyridine; Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hyperemia; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Time Factors; Triterpenes; Vasodilation | 2008 |
Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade.
Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Amino Acids; Animals; Baclofen; Barium; Bee Venoms; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cesium; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Potassium Channel Blockers; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Theophylline; Xanthenes | 2011 |