theasinensin-a and afzelechin

theasinensin-a has been researched along with afzelechin* in 1 studies

Other Studies

1 other study(ies) available for theasinensin-a and afzelechin

Article	Year
An emerging strategy for evaluating the grades of Keemun black tea by combinatory liquid chromatography-Orbitrap mass spectrometry-based untargeted metabolomics and inhibition effects on α-glucosidase and α-amylase. Food chemistry, 2018, Apr-25, Volume: 246 Quantitative analysis and untargeted liquid chromatography mass spectrum (LC-MS) based metabolomics of different grades of Keemun black tea (KBT) were conducted. Quantitative analysis did not show tight correlation between tea grades and contents of polyphenols, but untargeted metabolomics analysis revealed that high-grades KBT were distinguished from the low-grades. S-plot and Variable Importance (VIP) analysis gave 28 marker compounds responsible for the discrimination of different grades of KBT. The inhibitory effects of KBT on α-amylase and α-glucosidase were positively correlated to tea grades, and the correlation coefficient between each marker compound and inhibitory rate were calculated. Thirteen compounds were positively related to the anti-glycemic activity, and theasinensin A, afzelechin gallate and kaempferol-glucoside were confirmed as grade-related bioactive marker compounds by chemical and bioassay in effective fractions. This study suggested that combinatory metabolomics and bioactivities assay provided a new strategy for the classification of tea grades. Topics: alpha-Amylases; alpha-Glucosidases; Benzopyrans; Biomarkers; Chromatography, High Pressure Liquid; Cluster Analysis; Flavonoids; Food Analysis; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Metabolomics; Phenols; Polyphenols; Tandem Mass Spectrometry; Tea	2018

Article

Year

An emerging strategy for evaluating the grades of Keemun black tea by combinatory liquid chromatography-Orbitrap mass spectrometry-based untargeted metabolomics and inhibition effects on α-glucosidase and α-amylase.

Food chemistry, 2018, Apr-25, Volume: 246

Quantitative analysis and untargeted liquid chromatography mass spectrum (LC-MS) based metabolomics of different grades of Keemun black tea (KBT) were conducted. Quantitative analysis did not show tight correlation between tea grades and contents of polyphenols, but untargeted metabolomics analysis revealed that high-grades KBT were distinguished from the low-grades. S-plot and Variable Importance (VIP) analysis gave 28 marker compounds responsible for the discrimination of different grades of KBT. The inhibitory effects of KBT on α-amylase and α-glucosidase were positively correlated to tea grades, and the correlation coefficient between each marker compound and inhibitory rate were calculated. Thirteen compounds were positively related to the anti-glycemic activity, and theasinensin A, afzelechin gallate and kaempferol-glucoside were confirmed as grade-related bioactive marker compounds by chemical and bioassay in effective fractions. This study suggested that combinatory metabolomics and bioactivities assay provided a new strategy for the classification of tea grades.

Topics: alpha-Amylases; alpha-Glucosidases; Benzopyrans; Biomarkers; Chromatography, High Pressure Liquid; Cluster Analysis; Flavonoids; Food Analysis; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Metabolomics; Phenols; Polyphenols; Tandem Mass Spectrometry; Tea

2018