Page last updated: 2024-08-16

thalidomide and zoledronic acid

thalidomide has been researched along with zoledronic acid in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (50.00)29.6817
2010's14 (41.18)24.3611
2020's3 (8.82)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Hussein, MA; Juturi, JV; Lieberman, I1
Dolan, G; Jones, SG; Lengyel, K; Myers, B1
Avcu, F; Nevruz, O; Pekel, A; Sengul, A; Ural, AU; Yalcin, A; Yilmaz, MI; Zerman, M1
Rajkumar, SV1
Chou, T1
Baccarani, M; Boni, P; Cangini, D; Cavo, M; Ceccolini, M; Cellini, C; Parente, R; Perrone, G; Tacchetti, P; Tosi, P; Tura, S; Zamagni, E1
Bemardeschi, P; Dentico, P; Fiorentini, G; Giustarini, G; Rossi, S; Turano, E1
Do, KA; Jonasch, E; Lin, P; Lin, SH; Mathew, P; Pagliaro, LC; Rhines, L; Siefker-Radtke, A; Tannir, N; Tibbs, R; Tu, SM1
McKenna, KE; Morris, TC; Ramadan, KM1
Baccarani, M; Brioli, A; Cangini, D; Catalano, L; Cavo, M; Ceccolini, M; Cellini, C; D'Arco, A; Di Raimondo, F; Offidani, M; Perrone, G; Ronconi, S; Tacchetti, P; Tosi, P; Tura, S; Zamagni, E1
Alpay, N; Ayer, M; Küçükkaya, RD; Mete, O; Nalçaci, M; Yavuz, AS; Yenerel, MN; Yildirim, ND1
Bilic, S; Copeman, M; Cremers, S; Kennedy, N; Lynch, K; Neeman, T; Ravera, C; Roberts, A; Schran, H; Spencer, A1
Adam, Z; Krejcí, M; Krikavová, L; Mechl, M; Moulis, M; Navrátil, M; Neumann, C; Pour, L; Vanícek, J; Veselý, K; Vorlícek, J1
Bamia, C; Bamias, A; Christoulas, D; Dimopoulos, MA; Eleftherakis-Papaiakovou, E; Gika, D; Kastritis, E; Melakopoulos, I; Migkou, M; Roussou, M; Terpos, E1
Arima, S; Hayakawa, K; Hoshinaga, K; Kusaka, M; Maruyama, T; Miyakawa, S; Mori, S; Sasaki, H; Shiroki, R1
Aki, SZ; Cetiner, M; Cetiner, S; Gultekin, SE; Haznedar, R; Kahraman, SA; Kocakahyaoglu, B; Sucak, GT1
Gnanapandithan, K; Kumar, S; Malhotra, P; Sharma, A; Singh, S; Varma, S1
Chen, Y; Kim, K; Kim, YK; Pai, VR; Srivastava, A; Suh, C; Teoh, G; Yoon, SS1
Iida, S1
Ashcroft, AJ; Bell, SE; Child, JA; Davies, FE; Drayson, MT; Gregory, WM; Jackson, GH; Morgan, GJ; Owen, RG; Szubert, AJ1
Dispenzieri, A; Gertz, MA; Greipp, PR; Hassoun, H; Hayman, SR; Kumar, S; Lacy, MQ; Laumann, KM; Lust, JA; Mandrekar, SJ; Rajkumar, SV; Reeder, CB; Roy, V; Witzig, TE1
Locke, FL; Morgan, GJ1
Suzuki, K1
McCarthy, PL1
Anderson, KC; Bianchi, G; Richardson, PG1
Dong, W; Liu, J; Qi, M; Song, Z; Sun, H; Yin, L1
Abe, M; Aihara, K; Amachi, R; Bat-Erdene, A; Cui, Q; Endo, I; Fujii, S; Harada, T; Iwasa, M; Kagawa, K; Matsumoto, T; Miki, H; Nakamura, S; Oda, A; Ozaki, S; Sogabe, K; Teramachi, J; Yoshida, S1
Li, Z; Mao, T; Sheng, J; Xu, L; Yu, Y1
Bell, SE; Cairns, DA; Child, JA; Cook, G; Davies, FE; Drayson, MT; Gregory, WM; Jackson, GH; Morgan, GJ; Owen, RG; Royle, KL1
Dalgleish, AG; Kasow, S; Samad, M; Smith, PL; Yogaratnam, Y1
Kasinathan, G1

Reviews

9 review(s) available for thalidomide and zoledronic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Multiple myeloma: present and future.
    Current opinion in oncology, 2002, Volume: 14, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Bone Marrow Transplantation; Diphosphonates; Humans; Imidazoles; Multiple Myeloma; Oxides; Pamidronate; Thalidomide; Zoledronic Acid

2002
Thalidomide in newly diagnosed multiple myeloma and overview of experience in smoldering/indolent disease.
    Seminars in hematology, 2003, Volume: 40, Issue:4 Suppl 4

    Topics: Adjuvants, Immunologic; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dexamethasone; Diphosphonates; Female; Humans; Imidazoles; Life Tables; Male; Middle Aged; Multiple Myeloma; Randomized Controlled Trials as Topic; Survival Analysis; Thalidomide; Treatment Outcome; Zoledronic Acid

2003
[Multiple myeloma--recent advances in diagnosis and treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:3

    Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Combined Modality Therapy; Diphosphonates; Dose-Response Relationship, Drug; Hematopoietic Stem Cell Transplantation; Humans; Imidazoles; Multiple Myeloma; Neoplasm Staging; Pamidronate; Protease Inhibitors; Pyrazines; Thalidomide; Zoledronic Acid

2005
[Multiple myeloma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2012, Volume: 53, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Denosumab; Diphosphonates; Humans; Imidazoles; Melphalan; Multiple Myeloma; Peripheral Nervous System Diseases; Prednisolone; Pyrazines; Randomized Controlled Trials as Topic; Thalidomide; Zoledronic Acid

2012
What is the evidence for the use of bisphosphonate therapy in newly diagnosed multiple myeloma patients lacking bone disease?
    Hematology. American Society of Hematology. Education Program, 2012, Volume: 2012

    Topics: Bone Diseases; Boronic Acids; Bortezomib; Dexamethasone; Diphosphonates; Fatigue; Fractures, Bone; Humans; Imidazoles; In Situ Hybridization, Fluorescence; Lenalidomide; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Myeloma; Proteinuria; Pyrazines; Randomized Controlled Trials as Topic; Thalidomide; Time Factors; Translocation, Genetic; Treatment Outcome; Zoledronic Acid

2012
Current therapeutic strategy for multiple myeloma.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:2

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Density Conservation Agents; Boronic Acids; Bortezomib; Clinical Trials as Topic; Creatinine; Cyclophosphamide; Denosumab; Dexamethasone; Diphosphonates; Doxorubicin; Hematopoietic Stem Cell Transplantation; Humans; Imidazoles; Immunoglobulins; Kidney; Lenalidomide; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Melphalan; Molecular Targeted Therapy; Multiple Myeloma; Neoplasms, Second Primary; Precision Medicine; Prednisolone; Pyrazines; Quality of Life; Recurrence; Remission Induction; Survival Rate; Thalidomide; Zoledronic Acid

2013
Part I: the role of maintenance therapy in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2013, Jan-01, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Bone Density Conservation Agents; Boronic Acids; Bortezomib; Diphosphonates; Hematopoietic Stem Cell Transplantation; Humans; Imidazoles; Immunologic Factors; Lenalidomide; Maintenance Chemotherapy; Multiple Myeloma; Pyrazines; Thalidomide; Transplantation, Autologous; Zoledronic Acid

2013
Use of zoledronic acid combined with thalidomide in the treatment of Gorham-Stout disease.
    Rheumatology (Oxford, England), 2018, Jun-01, Volume: 57, Issue:6

    Topics: Adult; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, Combination; Follow-Up Studies; Humans; Imidazoles; Immunosuppressive Agents; Male; Osteolysis, Essential; Thalidomide; Tomography, X-Ray Computed; Zoledronic Acid

2018

Trials

9 trial(s) available for thalidomide and zoledronic acid

ArticleYear
First-line therapy with thalidomide, dexamethasone and zoledronic acid decreases bone resorption markers in patients with multiple myeloma.
    European journal of haematology, 2006, Volume: 76, Issue:5

    Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Remodeling; Bone Resorption; Collagen Type I; Dexamethasone; Diphosphonates; Female; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Osteocalcin; Pain; Peptides; Thalidomide; Treatment Outcome; Zoledronic Acid

2006
Low-dose thalidomide plus monthly high-dose oral dexamethasone (Thali-Dexa): results, prognostic factors and side effects in eight patients previously treated with multiple myeloma.
    Journal of experimental & clinical cancer research : CR, 2003, Volume: 22, Issue:4 Suppl

    Topics: Administration, Oral; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Sedimentation; Dexamethasone; Diphosphonates; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Pamidronate; Prognosis; Salvage Therapy; Survival Analysis; Thalidomide; Treatment Outcome; Zoledronic Acid

2003
Pilot trial of bone-targeted therapy with zoledronate, thalidomide, and interferon-gamma for metastatic renal cell carcinoma.
    Cancer, 2006, Aug-01, Volume: 107, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Renal Cell; Diphosphonates; Female; Humans; Imidazoles; Interferon-gamma; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Thalidomide; Zoledronic Acid

2006
Osteonecrosis of the jaws in newly diagnosed multiple myeloma patients treated with zoledronic acid and thalidomide-dexamethasone.
    Blood, 2006, Dec-01, Volume: 108, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Dexamethasone; Diphosphonates; Female; Humans; Imidazoles; Jaw Diseases; Male; Multiple Myeloma; Osteonecrosis; Retrospective Studies; Thalidomide; Zoledronic Acid

2006
Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study.
    BMC clinical pharmacology, 2008, Mar-31, Volume: 8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Diphosphonates; Female; Humans; Imidazoles; Kidney; Male; Middle Aged; Multiple Myeloma; Prednisolone; Thalidomide; Zoledronic Acid

2008
Lower dose dexamethasone/thalidomide and zoledronic acid every 3 weeks in previously untreated multiple myeloma.
    Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Diphosphonates; Female; Humans; Imidazoles; Male; Middle Aged; Models, Biological; Multiple Myeloma; Thalidomide; Treatment Outcome; Zoledronic Acid

2012
Effects of induction and maintenance plus long-term bisphosphonates on bone disease in patients with multiple myeloma: the Medical Research Council Myeloma IX Trial.
    Blood, 2012, Jun-07, Volume: 119, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Bone Diseases; Clodronic Acid; Diphosphonates; Female; Follow-Up Studies; Humans; Imidazoles; Induction Chemotherapy; Male; Middle Aged; Multiple Myeloma; Thalidomide; Zoledronic Acid

2012
A phase III randomized trial of thalidomide plus zoledronic acid versus zoledronic acid alone in patients with asymptomatic multiple myeloma.
    Leukemia, 2013, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Diphosphonates; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Imidazoles; Immunosuppressive Agents; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Prognosis; Survival Rate; Thalidomide; Zoledronic Acid

2013
Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study.
    British journal of haematology, 2018, Volume: 182, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clodronic Acid; Consolidation Chemotherapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Longitudinal Studies; Maintenance Chemotherapy; Male; Middle Aged; Multiple Myeloma; Quality of Life; Remission Induction; Self Report; Surveys and Questionnaires; Thalidomide; Transplantation, Autologous; Young Adult; Zoledronic Acid

2018

Other Studies

16 other study(ies) available for thalidomide and zoledronic acid

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Severe increase in creatinine with hypocalcaemia in thalidomide-treated myeloma patients receiving zoledronic acid infusions.
    British journal of haematology, 2002, Volume: 119, Issue:2

    Topics: Aged; Creatinine; Diphosphonates; Female; Humans; Hypocalcemia; Imidazoles; Immunosuppressive Agents; Male; Multiple Myeloma; Thalidomide; Zoledronic Acid

2002
The bisphosphonate zoledronic acid induces cytotoxicity in human myeloma cell lines with enhancing effects of dexamethasone and thalidomide.
    International journal of hematology, 2003, Volume: 78, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Calcium; Cell Cycle; Cell Division; Dexamethasone; Diphosphonates; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Humans; Imidazoles; Leukemia, Plasma Cell; Multiple Myeloma; Neoplasm Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protein Kinase C; Staurosporine; Thalidomide; Tumor Cells, Cultured; Zoledronic Acid

2003
Clinical response of cutaneous squamous-cell carcinoma to bortezomib given for myeloma.
    The Lancet. Oncology, 2006, Volume: 7, Issue:11

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Carcinoma, Squamous Cell; Clarithromycin; Dexamethasone; Diphosphonates; Glomerulonephritis; Humans; Idarubicin; Imidazoles; Immunosuppressive Agents; Male; Melphalan; Middle Aged; Multiple Myeloma; Nephrotic Syndrome; Pamidronate; Protein Synthesis Inhibitors; Pyrazines; Skin Neoplasms; Thalidomide; Zoledronic Acid

2006
Leukocytoclastic vasculitis due to thalidomide in multiple myeloma.
    Japanese journal of clinical oncology, 2007, Volume: 37, Issue:9

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Bone Density Conservation Agents; Diphosphonates; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Recurrence; Thalidomide; Vasculitis, Leukocytoclastic, Cutaneous; Zoledronic Acid

2007
[Treatment of multiple angiomatosis involving the skeleton and the abdominal and thoracic cavities with interferon alpha, thalidomide and zoledronate].
    Vnitrni lekarstvi, 2008, Volume: 54, Issue:6

    Topics: Adult; Angiogenesis Inhibitors; Angiomatosis; Diagnosis, Differential; Diphosphonates; Drug Therapy, Combination; Humans; Imidazoles; Interferon-alpha; Male; Mediastinal Diseases; Peritoneal Diseases; Spinal Diseases; Thalidomide; Zoledronic Acid

2008
Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Density Conservation Agents; Boronic Acids; Bortezomib; Dental Prophylaxis; Diphosphonates; Female; Humans; Imidazoles; Incidence; Jaw Diseases; Male; Middle Aged; Multiple Myeloma; Osteonecrosis; Pyrazines; Retrospective Studies; Thalidomide; Young Adult; Zoledronic Acid

2009
[Zoledronic acid for bone metastases due to advanced renal cell carcinoma under chronic hemodialysis--a report of two cases].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2008, Volume: 99, Issue:5

    Topics: Aged; Bone Density Conservation Agents; Bone Neoplasms; Calcium; Carcinoma, Renal Cell; Chronic Disease; Diphosphonates; Drug Therapy, Combination; Humans; Imidazoles; Infusions, Intravenous; Interleukin-2; Kidney Failure, Chronic; Kidney Neoplasms; Male; Middle Aged; Monitoring, Physiologic; Renal Dialysis; Thalidomide; Zoledronic Acid

2008
Osteonecrosis of the jaw in patients with multiple myeloma treated with zoledronic acid.
    Journal of bone and mineral metabolism, 2009, Volume: 27, Issue:4

    Topics: Adult; Aged; Bone Density Conservation Agents; Bone Resorption; Dexamethasone; Diphosphonates; Female; Humans; Imidazoles; Jaw; Male; Middle Aged; Multiple Myeloma; Necrosis; Osteoclasts; Osteonecrosis; Thalidomide; Zoledronic Acid

2009
Development of multiple myeloma in a case of longstanding ankylosing spondylitis: more than a coincidence?
    International journal of rheumatic diseases, 2011, Volume: 14, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Diphosphonates; Etoricoxib; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Pyridines; Sacroiliitis; Spondylitis, Ankylosing; Sulfones; Thalidomide; Zoledronic Acid

2011
Best treatment strategies in high-risk multiple myeloma: navigating a gray area.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jul-10, Volume: 32, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Back Pain; Biopsy; Bone Density Conservation Agents; Bone Marrow; Boronic Acids; Bortezomib; Dexamethasone; Diphosphonates; Fatigue; Hematopoietic Stem Cell Transplantation; Humans; Imidazoles; Immunoglobulin G; Immunoglobulin lambda-Chains; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Pyrazines; Referral and Consultation; Thalidomide; Translocation, Genetic; Transplantation, Autologous; Zoledronic Acid

2014
[Effect of thalidomide on development of bisphosphonate-related osteonecrosis of the jaws in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2015, Volume: 35, Issue:8

    Topics: Animals; Apoptosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density; Diphosphonates; Disease Models, Animal; Imidazoles; Molar; Neovascularization, Physiologic; Rats; Thalidomide; Tooth Extraction; Zoledronic Acid

2015
Expansion of Th
    Leukemia, 2017, Volume: 31, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Diphosphonates; Humans; Imidazoles; Immunologic Factors; Lenalidomide; Multiple Myeloma; T-Lymphocytes; Th1 Cells; Thalidomide; Zoledronic Acid

2017
Effect of Gemcitabine based chemotherapy on the immunogenicity of pancreatic tumour cells and T-cells.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:1

    Topics: Annexin A5; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Dendritic Cells; Deoxycytidine; Drug Interactions; Gemcitabine; Histocompatibility Antigens Class I; Humans; Immunomodulation; Interferon-gamma; Lymphocyte Activation; Oxaliplatin; Pancreatic Neoplasms; Thalidomide; Zoledronic Acid

2021
Primary plasma cell leukaemia in a 39-year-old man.
    BMJ case reports, 2020, Jul-23, Volume: 13, Issue:7

    Topics: Adult; Antineoplastic Agents; Bone Density Conservation Agents; Bone Marrow; Bortezomib; Dexamethasone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Immunoglobulin G; Immunoglobulin lambda-Chains; Immunosuppressive Agents; Leukemia, Plasma Cell; Male; Thalidomide; Zoledronic Acid

2020