Page last updated: 2024-08-16

thalidomide and transforming growth factor beta

thalidomide has been researched along with transforming growth factor beta in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.35)18.2507
2000's12 (52.17)29.6817
2010's6 (26.09)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
Flockhart, DA; Greenlee, BM; Karp, CL; Ma, X; Moller, DR; Trinchieri, G; Wahl, L; Wysocka, M1
Allampallam, K; Dar, S; Dutt, D; Gezer, S; Lisak, L; Nascimben, F; Raza, A; Shetty, V; Venugopal, P; York, A; Zorat, F1
Pozzato, G; Zorat, F1
Chen, MF; Ho, YP; Huang, SF; Jan, YY; Yeh, JN; Yeh, TS1
Hunt, BJ; Jones, R; Parmar, K; Schey, S; Streetly, M; Zeldis, J1
Haruta, S; Inagaki, K; Kanayama, N; Kawaguchi, R; Kitanaka, T; Kobayashi, H; Kondo, T; Kurita, N; Sakamoto, Y; Terao, T; Yagyu, T; Yamada, Y1
Chiu, YT; Chong, LW; Hsu, YC; Huang, YT; Yang, KC1
Crisafulli, C; Cuzzocrea, S; Di Paola, R; Genovese, T; Malleo, G; Mazzon, E; Muià, C; Siriwardena, AK1
Asaoku, H; Katayama, Y; Kimura, A; Kubo, T; Kuroda, Y; Munemasa, S; Okikawa, Y; Sakai, A; Shimose, S1
Bartlett, JB; Chen, R; Dalgleish, AG; Dredge, K; Galustian, C; Henry, J; Klaschka, D; Labarthe, MC; Meyer, B; Muller, G; Schafer, P; Stirling, D; Todryk, S1
Aloisi, C; Buemi, M; Crisafulli, C; Cuzzocrea, S; Di Paola, R; Mazzon, E; Mondello, P; Mondello, S1
Bueso-Ramos, C; Cortes, J; Ferrajoli, A; Garcia-Manero, G; Kantarjian, HM; Manshouri, T; Quintás-Cardama, A; Ravandi, F; Thomas, D; Verstovsek, S1
Alexandrescu, S; Brown, RE; Burns, NK; Covinsky, MH; Czerniak, BA; Tatevian, N1
List, AF1
Han, W; Liu, J; Wang, S; Wang, X; Yan, Q; Yang, X1
Balaian, E; Bornhäuser, M; Ehninger, G; Germing, U; Haase, D; Mohr, B; Oelschlaegel, U; Ordemann, R; Platzbecker, U; Schönefeldt, C; Schuster, C; Tuve, S; von Bonin, M; Wermke, M1
Giagounidis, A1
Bian, C; Chen, J; Qin, WJ; Wang, YY; Zhang, CY; Zhao, R; Zhe, H; Zhu, YZ; Zou, GL1
Marafini, I; Monteleone, G; Salvatori, S; Troncone, E1
Fan, LJ; Jiang, P; Li, XG; Lv, P; Meng, QS; Zhang, J; Zhao, ZH1
Alampady, V; Baby, K; Byregowda, BH; Dsouza, NN; Maity, S; Nayak, Y1
Guo, R; He, J; Hou, M; Jiang, JH; Ren, T; Wang, T1

Reviews

6 review(s) available for thalidomide and transforming growth factor beta

ArticleYear
Thalidomide in myelodysplastic syndromes.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2002, Volume: 56, Issue:1

    Topics: Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents; Chromosome Aberrations; Constipation; Cytokines; Dyspnea; Fatigue; Humans; Immunosuppressive Agents; Interleukin-1; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Thalidomide; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2002
[Pathophysiology of and therapy for primary myelofibrosis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Aug-10, Volume: 96, Issue:8

    Topics: Animals; Cytokines; Hematopoietic Stem Cell Transplantation; Humans; Janus Kinase 2; Mutation; Primary Myelofibrosis; Signal Transduction; Thalidomide; Transforming Growth Factor beta; Transplantation, Homologous

2007
New therapeutics for myelodysplastic syndromes.
    Leukemia research, 2012, Volume: 36, Issue:12

    Topics: Antineoplastic Agents; Azacitidine; Bone Marrow; Chromosomes, Human, Pair 5; Glycine; Humans; Hydroxamic Acids; Lenalidomide; Myelodysplastic Syndromes; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Sequence Deletion; Sulfones; Thalidomide; Transforming Growth Factor beta; Tumor Microenvironment

2012
Current treatment algorithm for the management of lower-risk MDS.
    Hematology. American Society of Hematology. Education Program, 2017, 12-08, Volume: 2017, Issue:1

    Topics: Algorithms; Allografts; Erythrocyte Transfusion; Erythropoietin; Hematinics; Humans; Immunosuppressive Agents; Lenalidomide; Myelodysplastic Syndromes; Stem Cell Transplantation; Thalidomide; Transforming Growth Factor beta

2017
TGF-β activity restoration and phosphodiesterase 4 inhibition as therapeutic options for inflammatory bowel diseases.
    Pharmacological research, 2020, Volume: 155

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammatory Bowel Diseases; Oligonucleotides; Phosphodiesterase 4 Inhibitors; Thalidomide; Thiazoles; Transforming Growth Factor beta

2020
Thalidomide interaction with inflammation in idiopathic pulmonary fibrosis.
    Inflammopharmacology, 2023, Volume: 31, Issue:3

    Topics: COVID-19; Humans; Idiopathic Pulmonary Fibrosis; Inflammation; Lung; Pandemics; Thalidomide; Transforming Growth Factor beta

2023

Trials

2 trial(s) available for thalidomide and transforming growth factor beta

ArticleYear
Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Oct-01, Volume: 27, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factor 2; Glucocorticoids; Humans; Janus Kinase 2; Lenalidomide; Male; Middle Aged; Mutation; Neutropenia; Platelet-Derived Growth Factor; Prednisone; Primary Myelofibrosis; Thalidomide; Thrombocytopenia; Transforming Growth Factor beta; Treatment Outcome

2009
Selective expansion of regulatory T cells during lenalidomide treatment of myelodysplastic syndrome with isolated deletion 5q.
    Annals of hematology, 2016, Volume: 95, Issue:11

    Topics: Aged; Aged, 80 and over; Anemia, Macrocytic; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 5; Female; Humans; Immunologic Factors; Lenalidomide; Male; Middle Aged; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thalidomide; Transforming Growth Factor beta

2016

Other Studies

15 other study(ies) available for thalidomide and transforming growth factor beta

ArticleYear
Inhibition of IL-12 production by thalidomide.
    Journal of immunology (Baltimore, Md. : 1950), 1997, Nov-15, Volume: 159, Issue:10

    Topics: Antibodies, Monoclonal; Cells, Cultured; Humans; Immunosuppressive Agents; Indomethacin; Interleukin-10; Interleukin-12; Leukocytes, Mononuclear; Lymphocyte Activation; Monocytes; RNA, Messenger; Thalidomide; Transforming Growth Factor beta

1997
The clinical and biological effects of thalidomide in patients with myelodysplastic syndromes.
    British journal of haematology, 2001, Volume: 115, Issue:4

    Topics: Aged; Case-Control Studies; Cytokines; Endothelial Growth Factors; Female; Hemoglobins; Humans; Immunosuppressive Agents; Lymphokines; Male; Myelodysplastic Syndromes; Platelet Count; Remission Induction; Thalidomide; Transforming Growth Factor alpha; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Thalidomide salvages lethal hepatic necroinflammation and accelerates recovery from cirrhosis in rats.
    Journal of hepatology, 2004, Volume: 41, Issue:4

    Topics: Animals; Collagenases; Hepatitis; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Male; Matrix Metalloproteinase 13; Necrosis; Rats; Rats, Sprague-Dawley; Salvage Therapy; Thalidomide; Time Factors; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2004
Markers of endothelial and haemostatic function in the treatment of relapsed myeloma with the immunomodulatory agent Actimid (CC-4047) and their relationship with venous thrombosis.
    European journal of haematology, 2005, Volume: 74, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; Female; Fibrin Fibrinogen Degradation Products; Hemostasis; Humans; Immunologic Factors; Interleukin-6; Male; Middle Aged; Multiple Myeloma; Thalidomide; Transforming Growth Factor beta; Transforming Growth Factor beta2; Vascular Endothelial Growth Factor A; Venous Thrombosis

2005
Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kappaB activation and subsequently suppressed ovarian cancer dissemination.
    Cancer research, 2005, Nov-15, Volume: 65, Issue:22

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chondrosarcoma; Drug Synergism; Female; Gene Expression; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Ovarian Neoplasms; Paclitaxel; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Thalidomide; Transforming Growth Factor beta; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator; Xenograft Model Antitumor Assays

2005
Anti-fibrotic effects of thalidomide on hepatic stellate cells and dimethylnitrosamine-intoxicated rats.
    Journal of biomedical science, 2006, Volume: 13, Issue:3

    Topics: Actins; Animals; Collagen; Dimethylnitrosamine; Fibrosis; I-kappa B Proteins; Immunosuppressive Agents; Liver; Liver Cirrhosis, Experimental; Muscle, Smooth; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Thalidomide; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2006
Effects of thalidomide in a mouse model of cerulein-induced acute pancreatitis.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:1

    Topics: Animals; Apoptosis; Ceruletide; Disease Models, Animal; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Mice; Neutrophils; P-Selectin; Pancreatitis, Acute Necrotizing; Thalidomide; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2008
Osteoprogenitor differentiation is not affected by immunomodulatory thalidomide analogs but is promoted by low bortezomib concentration, while both agents suppress osteoclast differentiation.
    International journal of oncology, 2008, Volume: 33, Issue:1

    Topics: Alkaline Phosphatase; Apoptosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Boronic Acids; Bortezomib; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Immunologic Factors; Lenalidomide; Multiple Myeloma; Osteoblasts; Osteoclasts; Pyrazines; Thalidomide; Transforming Growth Factor beta

2008
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.
    Cancer immunology, immunotherapy : CII, 2009, Volume: 58, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Female; Forkhead Transcription Factors; Glucocorticoid-Induced TNFR-Related Protein; Humans; Immunosuppressive Agents; Interleukin-10; Lenalidomide; Mice; Mice, Inbred BALB C; Receptors, Nerve Growth Factor; Receptors, OX40; Receptors, Transforming Growth Factor beta; Receptors, Tumor Necrosis Factor; T-Lymphocytes, Regulatory; Thalidomide; Transforming Growth Factor beta

2009
Thalidomide suppresses sclerosing encapsulating peritonitis in a rat experimental model.
    Shock (Augusta, Ga.), 2009, Volume: 32, Issue:3

    Topics: Animals; Anti-Infective Agents; Blotting, Western; Chlorhexidine; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; I-kappa B Proteins; Immunohistochemistry; Immunosuppressive Agents; NF-kappa B; Nitric Oxide Synthase Type II; Peritonitis; Peroxidase; Poly Adenosine Diphosphate Ribose; Rats; Thalidomide; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Endothelial Growth Factor A

2009
Morphoproteomics provides support for TGF-β pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis.
    International journal of clinical and experimental pathology, 2012, Volume: 5, Issue:6

    Topics: Biomarkers; Cell Differentiation; Cell Membrane; Cell Nucleus; Child; Child, Preschool; Cytoplasm; Female; Histiocytosis, Langerhans-Cell; Humans; Kruppel-Like Transcription Factors; Male; Nuclear Proteins; Osteoclasts; Osteolysis; Proteomics; Signal Transduction; Thalidomide; Transforming Growth Factor beta; Zinc Finger Protein Gli2

2012
Investigating the role of angiogenesis in systemic lupus erythematosus.
    Lupus, 2015, Volume: 24, Issue:6

    Topics: Adult; Angiogenesis Inhibitors; Autoantibodies; Biomarkers; Endostatins; Female; Fibroblast Growth Factor 2; Hepatocyte Growth Factor; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neovascularization, Pathologic; Placenta Growth Factor; Pregnancy Proteins; Thalidomide; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2015
Thalidomide (THD) alleviates radiation induced lung fibrosis (RILF) via down-regulation of TGF-β/Smad3 signaling pathway in an Nrf2-dependent manner.
    Free radical biology & medicine, 2018, Volume: 129

    Topics: A549 Cells; Animals; Cell Line, Tumor; Epithelial Cells; Female; Gene Expression Regulation; Humans; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Pulmonary Fibrosis; Radiation Injuries, Experimental; Radiation-Protective Agents; Reactive Oxygen Species; Signal Transduction; Smad3 Protein; Thalidomide; THP-1 Cells; Transforming Growth Factor beta; X-Rays

2018
Thalidomide Reduces Activation of Murine Pancreatic Stellate Cells by Inhibiting the TGF-β/Smad Pathway.
    Annals of clinical and laboratory science, 2021, Volume: 51, Issue:3

    Topics: Actins; Angiogenesis Inhibitors; Animals; Collagen Type I; Male; Mice; Mice, Inbred C57BL; Pancreatic Stellate Cells; Signal Transduction; Smad3 Protein; Smad7 Protein; Thalidomide; Transforming Growth Factor beta

2021
Selective Proteolysis of Activated Transcriptional Factor by NIR-Responsive Palindromic DNA Thalidomide Conjugate Inhibits the Canonical Smad Pathway.
    Small (Weinheim an der Bergstrasse, Germany), 2023, Volume: 19, Issue:44

    Topics: DNA; Gene Expression Regulation; Proteolysis; Thalidomide; Transcription Factors; Transforming Growth Factor beta

2023